ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0655 good J KOG0188 Translation, ribosomal structure and biogenesis Alanyl-tRNA synthetase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0655 220848 223715 956
(956 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR335c [J] KOG0188 Alanyl-tRNA synthetase 1498 0.0
SPAC23C11.09 [J] KOG0188 Alanyl-tRNA synthetase 1083 0.0
Hs4501841 [J] KOG0188 Alanyl-tRNA synthetase 854 0.0
At1g50200 [J] KOG0188 Alanyl-tRNA synthetase 851 0.0
7297398 [J] KOG0188 Alanyl-tRNA synthetase 839 0.0
CE09768 [J] KOG0188 Alanyl-tRNA synthetase 827 0.0
Hs20555071 [J] KOG0188 Alanyl-tRNA synthetase 600 e-171
ECU02g1490 [J] KOG0188 Alanyl-tRNA synthetase 517 e-146
CE28096 [J] KOG0188 Alanyl-tRNA synthetase 467 e-131
7295490 [J] KOG0188 Alanyl-tRNA synthetase 407 e-113
Hs13376886_2 [R] KOG2105 Predicted metal-dependent hydrolase con... 52 4e-06
>YOR335c [J] KOG0188 Alanyl-tRNA synthetase
Length = 958
Score = 1498 bits (3877), Expect = 0.0
Identities = 734/958 (76%), Positives = 823/958 (85%), Gaps = 2/958 (0%)
Query: 1 MTIGDKSKWTAANVRSTFLDYFKSKGHTFVPSSPVIPFDDPTLLFANAGMNQYKPIFLGT 60
MTIGDK KWTA NVR+TFLDYFKSK H FV SSPV+PFDDPTLLFANAGMNQYKPIFLGT
Sbjct: 1 MTIGDKQKWTATNVRNTFLDYFKSKEHKFVKSSPVVPFDDPTLLFANAGMNQYKPIFLGT 60
Query: 61 VDPSSDFYKLKRATNSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSFGDYFKKEAIE 120
VDP+SDFY LKRA NSQKCIRAGGKHNDLEDVG+DSYHHTFFEMLGNWSFGDYFKKEAI
Sbjct: 61 VDPASDFYTLKRAYNSQKCIRAGGKHNDLEDVGKDSYHHTFFEMLGNWSFGDYFKKEAIT 120
Query: 121 YSWELLTKVYGIPGDRLYVTYFEGDEKLGLEPDFEARDLWKSVGVKDDHILPGNAKDNFW 180
YSW LLT+VYGIP DRLYVTYFEGDEKLGLEPD EAR+LWK+VGV DDHILPGNAKDNFW
Sbjct: 121 YSWTLLTEVYGIPKDRLYVTYFEGDEKLGLEPDTEARELWKNVGVPDDHILPGNAKDNFW 180
Query: 181 EMGEQGPCGPCSEVHYDRIGGRNAAHLVNQDDPDVLEIWNNVFIQFNREQDRSLRALPAK 240
EMG+QGPCGPCSE+HYDRIGGRNAA LVN DDPDVLE+WN VFIQFNREQD SL+ LPAK
Sbjct: 181 EMGDQGPCGPCSEIHYDRIGGRNAASLVNMDDPDVLEVWNLVFIQFNREQDGSLKPLPAK 240
Query: 241 HVDTGMGFERLVSVLHDVRSNYDTDVFEPLFNRIQEITGVRSYTGKFGAEDTDGIDTAYR 300
H+DTGMGFERLVSVL DVRSNYDTDVF PLF RIQEIT VR Y+G FG D DGIDTAYR
Sbjct: 241 HIDTGMGFERLVSVLQDVRSNYDTDVFTPLFERIQEITSVRPYSGNFGENDKDGIDTAYR 300
Query: 301 VLADHVRTLTFALADGGVPNNEGRGYVXXXXXXXXXXXXXKYMNYPIGNFFSQLSVTLIE 360
VLADHVRTLTFALADGGVPNNEGRGYV KYMNYPIGNFFS L+ TLI
Sbjct: 301 VLADHVRTLTFALADGGVPNNEGRGYVLRRILRRGARYARKYMNYPIGNFFSTLAPTLIS 360
Query: 361 QVKDMFPEVARDPSYLFEILDEEEASFAKTLDRGEKLFEKYAEDALKKADKTLDGKQVWR 420
QV+D+FPE+A+DP++LFEILDEEEASFAKTLDRGE+LFEKYA A K KTLDGKQVWR
Sbjct: 361 QVQDIFPELAKDPAFLFEILDEEEASFAKTLDRGERLFEKYASAASKTESKTLDGKQVWR 420
Query: 421 LYDTYGFPVDLTELMAEEQGLKIDTIGFEKAKQESYEASXXXXXXXASDLIRLNVHELSQ 480
LYDTYGFPVDLTELMAEEQGLKID GFEKAKQESYEAS SDLI+LNVHELS+
Sbjct: 421 LYDTYGFPVDLTELMAEEQGLKIDGPGFEKAKQESYEASKRGGKKDQSDLIKLNVHELSE 480
Query: 481 LNGDNVAKTDDSSKYGTENVEATILRIYDGEKFVDSMTEIGKQYGVILDKTCFYAEQGGQ 540
LN V KT+D KYG+ NVE TIL+++DG FVD +TE GK+YG+ILDKTCFYAEQGGQ
Sbjct: 481 LNDAKVPKTNDEFKYGSANVEGTILKLHDGTNFVDEITEPGKKYGIILDKTCFYAEQGGQ 540
Query: 541 EFDTGKLVIDGEAEFNVDNVQAYNGYVFHTGSLGDGKLSIGDSIIASYEELRRHPLRNNH 600
E+DTGK+VID AEFNV+NVQ YNG+VFHTGSL +GKLS+GD IIAS++ELRR P++NNH
Sbjct: 541 EYDTGKIVIDDAAEFNVENVQLYNGFVFHTGSLEEGKLSVGDKIIASFDELRRFPIKNNH 600
Query: 601 TGTHILNFALKEVLGNDVDQKGSLVAPEKLRFDFSHKRALSYEELVEVEKLSNEKIRDNL 660
TGTHILNFALKE LGNDVDQKGSLVAPEKLRFDFSHK+A+S EEL +VE + NE+I++NL
Sbjct: 601 TGTHILNFALKETLGNDVDQKGSLVAPEKLRFDFSHKKAVSNEELKKVEDICNEQIKENL 660
Query: 661 TVYYKEVALDLAKTISSVRAVFGETYPDPVRVVSIGKAVEEVLENPTSEEWQKYSIEFCG 720
V+YKE+ LDLAK+I VRAVFGETYPDPVRVVS+GK +EE+L NP +EEW KYSIEFCG
Sbjct: 661 QVFYKEIPLDLAKSIDGVRAVFGETYPDPVRVVSVGKPIEELLANPANEEWTKYSIEFCG 720
Query: 721 GTHVAKTSDIKEFVIVEESGIAKGIRRIVAVSGPEAYEVQRIATEFDGELTAVEKLPFSP 780
GTHV KT DIK FVI+EESGIAKGIRRIVAV+G EA+E QR+A +F +L A +KLPFSP
Sbjct: 721 GTHVNKTGDIKYFVILEESGIAKGIRRIVAVTGTEAFEAQRLAEQFAADLDAADKLPFSP 780
Query: 781 LKAQKLKELGVRLGQLTISVITKTDLKDKFNKIEKEVKDELKSRAKKEIKQTLDDVKHHF 840
+K +KLKELGV+LGQL+ISVITK +LK KFNKIEK VKDE+KSRAKKE KQTLD+VK F
Sbjct: 781 IKEKKLKELGVKLGQLSISVITKNELKQKFNKIEKAVKDEVKSRAKKENKQTLDEVKTFF 840
Query: 841 DANKESSFYVKHIDIPTNAKAITEAINHIKTNS--KDKSIYLFTCNEPDGKVAHGCYISD 898
+ N+ + + VK IDI NAKAITEAIN++K+N KDKSIYL N+P+G+VAHGCYIS+
Sbjct: 841 ETNENAPYLVKFIDISPNAKAITEAINYMKSNDSVKDKSIYLLAGNDPEGRVAHGCYISN 900
Query: 899 AAIAQGVDGSSLAKTVSSSIXXXXXXXXNVFQGMGDKPNGIDSAVAEVEALLKERLTI 956
AA+A+G+DGS+LAK VSS I NVFQGMGDKP I AV ++E+L KE+L+I
Sbjct: 901 AALAKGIDGSALAKKVSSIIGGKAGGKGNVFQGMGDKPAAIKDAVDDLESLFKEKLSI 958
>SPAC23C11.09 [J] KOG0188 Alanyl-tRNA synthetase
Length = 959
Score = 1083 bits (2802), Expect = 0.0
Identities = 545/953 (57%), Positives = 683/953 (71%), Gaps = 8/953 (0%)
Query: 9 WTAANVRSTFLDYFKSKGHTFVPSSPVIPFDDPTLLFANAGMNQYKPIFLGTVDPSSDFY 68
W A +R TFL YF+ GHT VPSS VIP+DDPTLLFANAGMNQ+KPIFLGTVDPSSDF
Sbjct: 10 WPANEIRRTFLKYFEDHGHTIVPSSSVIPYDDPTLLFANAGMNQFKPIFLGTVDPSSDFA 69
Query: 69 KLKRATNSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSFGDYFKKEAIEYSWELLTK 128
KLKRA +SQKCIRAGGKHNDLEDVG+D+YHHT FEMLGNWSFGDYFKKEAI +W+LLT
Sbjct: 70 KLKRACDSQKCIRAGGKHNDLEDVGKDNYHHTMFEMLGNWSFGDYFKKEAIAMAWDLLTN 129
Query: 129 VYGIPGDRLYVTYFEGDEKLGLEPDFEARDLWKSVGVKDDHILPGNAKDNFWEMGEQGPC 188
VYG+ D+LYVTYF G E+ GLEPD EAR LW +G+ + ++PG+ KDNFWEMG+QGPC
Sbjct: 130 VYGLKKDQLYVTYFGGHEESGLEPDLEARQLWLDIGIDESRVIPGSLKDNFWEMGDQGPC 189
Query: 189 GPCSEVHYDRIGGRNAAHLVNQDDPDVLEIWNNVFIQFNREQDRSLRALPAKHVDTGMGF 248
GPCSE+HYDRIG R LVN DDP+VLEIWN VFIQFNRE+D SLR LP +HVDTGMGF
Sbjct: 190 GPCSEIHYDRIGNRTVPELVNMDDPNVLEIWNIVFIQFNREKDGSLRPLPNRHVDTGMGF 249
Query: 249 ERLVSVLHDVRSNYDTDVFEPLFNRIQEITGVRSYTGKFGAEDTDGIDTAYRVLADHVRT 308
ERLVSV+ + SNYDTDVF P+F +IQE+T R YTGK G ED DGIDTAYRV+ADHVRT
Sbjct: 250 ERLVSVIQNKTSNYDTDVFSPIFAKIQELTNARPYTGKMGDEDVDGIDTAYRVVADHVRT 309
Query: 309 LTFALADGGVPNNEGRGYVXXXXXXXXXXXXXKYMNYPIGNFFSQLSVTLIEQVKDMFPE 368
LTFA++DGGVPNNEGRGYV K PIGNFFS+LS+T++EQ+ D FPE
Sbjct: 310 LTFAISDGGVPNNEGRGYVLRRILRRGARYVRKKFGVPIGNFFSRLSLTVVEQMGDFFPE 369
Query: 369 VARDPSYLFEILDEEEASFAKTLDRGEKLFEKYAEDALKKADKTLDGKQVWRLYDTYGFP 428
+ R + E+LDEEE SF++TLDRGEK+FE+YA A K KTL G VWRLY+TYGFP
Sbjct: 370 LKRKVDDVRELLDEEEESFSRTLDRGEKMFEQYAAAAKKTPSKTLQGNDVWRLYETYGFP 429
Query: 429 VDLTELMAEEQGLKIDTIGFEKAKQESYEASXXXXXXXAS--DLIRLNVHELSQLNG-DN 485
VDLT LMAEE G+KID GFE A+ S E S +S DL+ L+VH L L+ D+
Sbjct: 430 VDLTHLMAEEAGIKIDEPGFEAAQARSKEISKQASKGGSSGDDLLVLDVHALGALSKMDD 489
Query: 486 VAKTDDSSKYGTENVEATILRIYDGEKFVDSMT--EIGKQYGVILDKTCFYAEQGGQEFD 543
+ +TDD K+ + ++++ I IY F S G+Q G++LD+T FYAEQGGQE+D
Sbjct: 490 IPETDDVFKHNSVSLKSVIKGIYHKGGFQKSTEGFNSGEQLGLLLDRTNFYAEQGGQEYD 549
Query: 544 TGKLVIDGEAEFNVDNVQAYNGYVFHTGSLGDGKLSIGDSIIASYEELRRHPLRNNHTGT 603
TG +VIDG A+F V NVQ Y GYV HTG L G L++ DS++ Y+E+RR L NNHT T
Sbjct: 550 TGHIVIDGVADFRVTNVQVYAGYVLHTGFLEYGNLTVNDSVVCEYDEIRRWHLMNNHTVT 609
Query: 604 HILNFALKEVLGNDVDQKGSLVAPEKLRFDFSHKRALSYEELVEVEKLSNEKIRDNLTVY 663
HILN AL+ LG+ +DQ+GSLV+ EKLRFDFS+K ++ ++L+ VE N I+DNL+VY
Sbjct: 610 HILNLALRNTLGDGIDQRGSLVSQEKLRFDFSYKSSIPIDKLLLVENYCNNVIQDNLSVY 669
Query: 664 YKEVALDLAKTISSVRAVFGETYPDPVRVVSIGKAVEEVLENPTSEEWQKYSIEFCGGTH 723
KEVAL AK I+ +RAVFGE YPDPVRVV IG ++ +L+ P +W KYSIEFCGGTH
Sbjct: 670 SKEVALSKAKEINGLRAVFGEVYPDPVRVVCIGVDIDTLLQEPKKPDWTKYSIEFCGGTH 729
Query: 724 VAKTSDIKEFVIVEESGIAKGIRRIVAVSGPEAYEVQRIATEFDGELTAVEKLPFSPLKA 783
K+ +IK+FVI+EE+GIAKGIRRIVAV+ EA V R+A EFD + +EK+PFSP K
Sbjct: 730 CDKSGEIKDFVILEENGIAKGIRRIVAVTSTEANRVSRLANEFDARIAKLEKMPFSPAKE 789
Query: 784 QKLKELGVRLGQLTISVITKTDLKDKFNKIEKEVKDELKSRAKKEIKQTLDDVKHHFDAN 843
+LK++ V L +L ++ + K +K++ KI K+V++ +K+ E K+ ++ V +F N
Sbjct: 790 AELKKISVDLSKLVVAAVRKHAMKERIAKITKQVQEHVKAINAAEQKEVVNVVTEYFKEN 849
Query: 844 KESSFYVKHIDIPTNAKAITEAINHIKTNSKDKSIYLFTCNEPDGKVAHGCYISDAAIAQ 903
+ SF V + I N KA++ A+ + K N KDKSIYL + D KVAH C +S A+ +
Sbjct: 850 PDMSFVVAKVPISANPKALSFALTYAKKNLKDKSIYLLASD--DTKVAHACLVSPEAMKK 907
Query: 904 GVDGSSLAKTVSSSIXXXXXXXXNVFQGMGDKPNGIDSAVAEVEALLKERLTI 956
+ ++ V SI + QG+GDKP ID AV E + +LTI
Sbjct: 908 -LTPQEWSQKVCHSIGGRSGGKGDTCQGVGDKPLSIDVAVEEAIEFFQGKLTI 959
>Hs4501841 [J] KOG0188 Alanyl-tRNA synthetase
Length = 968
Score = 854 bits (2207), Expect = 0.0
Identities = 456/930 (49%), Positives = 601/930 (64%), Gaps = 29/930 (3%)
Query: 7 SKWTAANVRSTFLDYFKSKGHTFVPSSPVIPFDDPTLLFANAGMNQYKPIFLGTVDPSSD 66
S TA+ +R F+D+FK HT+V SS IP DDPTLLFANAGMNQ+KPIFL T+DPS
Sbjct: 3 STLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHP 62
Query: 67 FYKLKRATNSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSFGDYFKKEAIEYSWELL 126
KL RA N+QKCIRAGGK NDL+DVG+D YHHTFFEMLG+WSFGDYFK+ A + + ELL
Sbjct: 63 MAKLSRAANTQKCIRAGGKQNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELL 122
Query: 127 TKVYGIPGDRLYVTYFEGDEKLGLEPDFEARDLWKSVGVKDDHILPGNAKDNFWEMGEQG 186
T+ +GIP +RLYVTYF GDE GLE D E + +W+++G+ D ILPGN KDNFWEMG+ G
Sbjct: 123 TQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTG 182
Query: 187 PCGPCSEVHYDRIGGRNAAHLVNQDDPDVLEIWNNVFIQFNREQDRSLRALPAKHVDTGM 246
PCGPCSE+HYDRIGGR+AAHLVNQDDP+VLEIWN VFIQ+NRE D L+ LP K +DTGM
Sbjct: 183 PCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGM 242
Query: 247 GFERLVSVLHDVRSNYDTDVFEPLFNRIQEITGVRSYTGKFGAEDTDGIDTAYRVLADHV 306
G ERLVSVL + SNYDTD+F P F IQ+ TG R YTGK GAED DGID AYRVLADH
Sbjct: 243 GLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHA 302
Query: 307 RTLTFALADGGVPNNEGRGYVXXXXXXXXXXXXXKYMNYPIGNFFSQLSVTLIEQVKDMF 366
RT+T ALADGG P+N GRGYV + +N G FF+ L +++ + D F
Sbjct: 303 RTITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRG-FFATLVDVVVQSLGDAF 361
Query: 367 PEVARDPSYLFEILDEEEASFAKTLDRGEKLFEKYAEDALKKADKTLDGKQVWRLYDTYG 426
PE+ +DP + +I++EEE F KTL RG ++ ++ + KT+ G W LYDTYG
Sbjct: 362 PELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSL--GDSKTIPGDTAWLLYDTYG 419
Query: 427 FPVDLTELMAEEQGLKIDTIGFEKAKQESYEASXXXXXXXASDLIRLNVHELSQLNGDNV 486
FPVDLT L+AEE+GL +D GFE+ ++ + + DLI L+++ + +L +
Sbjct: 420 FPVDLTGLIAEEKGLVVDMDGFEEERKLA-QLKSQGKGAGGEDLIMLDIYAIEELRARGL 478
Query: 487 AKTDDSSKYG----------TENVEATILRIYDGEKFVDSMTEIGKQYGVILDKTCFYAE 536
TDDS KY EN AT++ + + FV+ ++ G++ GV+LDKTCFYAE
Sbjct: 479 EVTDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVS-TGQECGVVLDKTCFYAE 537
Query: 537 QGGQEFDTGKLV-----IDGEAEFNVDNVQAYNGYVFHTGSLGDGKLSIGDSIIASYEEL 591
QGGQ +D G LV + + EF V N Q GYV H G++ G L +GD + +E
Sbjct: 538 QGGQIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTI-YGDLKVGDQVWLFIDEP 596
Query: 592 RRHPLRNNHTGTHILNFALKEVLGNDVDQKGSLVAPEKLRFDFSHKRALSYEELVEVEKL 651
RR P+ +NHT THILNFAL+ VLG + DQKGSLVAP++LRFDF+ K A+S +++ + E++
Sbjct: 597 RRRPIMSNHTATHILNFALRSVLG-EADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEI 655
Query: 652 SNEKIRDNLTVYYKEVALDLAKTISSVRAVFGETYPDPVRVVSIGKAVEEVLENPTSEEW 711
+NE I VY ++ L AK I +RAVF ETYPDPVRVVSIG V E+L++P+
Sbjct: 656 ANEMIEAAKAVYTQDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPSGPAG 715
Query: 712 QKYSIEFCGGTHVAKTSDIKEFVIVEESGIAKGIRRIVAVSGPEAYEVQRIATEFDGELT 771
S+EFCGGTH+ +S FVIV E IAKGIRRIVAV+G EA + R A L+
Sbjct: 716 SLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLS 775
Query: 772 AVE---KLPFSPLK--AQKLKELGVRLGQLTISVITKTDLKDKFNKIEKEVKDELKSRAK 826
+E K +P K +++ +LG L I K +L++ + K+V D+L +K
Sbjct: 776 VMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSL-KKVMDDLDRASK 834
Query: 827 KEI-KQTLDDVKHHFDANKESSFYVKHIDIPTNAKAITEAINHIKTNSKDKSIYLFTCNE 885
++ K+ L+ K D+N + ++ +AKA+ EA+ K +S S LFT +
Sbjct: 835 ADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFTVDN 894
Query: 886 PDGKVAHGCYISDAAIAQGVDGSSLAKTVS 915
GK+ C + A +G+ S + VS
Sbjct: 895 EAGKITCLCQVPQNAANRGLKASEWVQQVS 924
>At1g50200 [J] KOG0188 Alanyl-tRNA synthetase
Length = 1027
Score = 851 bits (2199), Expect = 0.0
Identities = 447/913 (48%), Positives = 590/913 (63%), Gaps = 38/913 (4%)
Query: 6 KSKWTAANVRSTFLDYFKSKGHTFVPSSPVIPFDDPTLLFANAGMNQYKPIFLGTVDPSS 65
+++W A VR T++D+F+ KGH F PSSPV+P +DPTLLFANAGMNQYKPIFLGT DP++
Sbjct: 56 ETQWPAKRVRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPNT 115
Query: 66 DFYKLKRATNSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSFGDYFKKEAIEYSWEL 125
+ KL RA N+QKCIRAGGKHNDL+DVG+D+YHHTFFEMLGNWSFGDYFKKEAIE++WEL
Sbjct: 116 ELSKLSRACNTQKCIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIEWAWEL 175
Query: 126 LTKVYGIPGDRLYVTYFEGDEKLGLEPDFEARDLWKSVGVKDDHILPGNAKDNFWEMGEQ 185
LTKVYG+P DR+Y TYF GDEK GL+PD EARD+W V + +LP KDNFWEMG+
Sbjct: 176 LTKVYGLPTDRIYATYFGGDEKAGLQPDNEARDIWLKV-LPSGRVLPFGCKDNFWEMGDT 234
Query: 186 GPCGPCSEVHYDRIGGRNAAHLVNQDDPDVLEIWNNVFIQFNREQDRSLRALPAKHVDTG 245
GPCGPC+E+HYDRIG R+AA LVN DDP LEIWN VFIQFNRE D SL+ LPAKHVDTG
Sbjct: 235 GPCGPCTEIHYDRIGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLKPLPAKHVDTG 294
Query: 246 MGFERLVSVLHDVRSNYDTDVFEPLFNRIQEITGVRSYTGKFGAEDTDGIDTAYRVLADH 305
MGFERL SVL + SNYDTDVF P+F+ IQ+ TG R Y+GK G ED D +D AYRV+ADH
Sbjct: 295 MGFERLTSVLQNKMSNYDTDVFMPIFDDIQKATGARPYSGKVGPEDVDRVDMAYRVVADH 354
Query: 306 VRTLTFALADGGVPNNEGRGYVXXXXXXXXXXXXXKYMNYPIGNFFSQLSVTLIEQVKDM 365
+RTL+FA+ADG P NEGR YV + + G FF+ L ++I + D+
Sbjct: 355 IRTLSFAIADGSRPGNEGREYVLRRILRRAVRYGKEILKAEEG-FFNGLVSSVIRVMGDV 413
Query: 366 FPEVARDPSYLFEILDEEEASFAKTLDRGEKLFEKYAEDALKKADKTLDGKQVWRLYDTY 425
F E+ + +I+ EEEASF KTL +G EK+ + TL G + L+DTY
Sbjct: 414 FTELKEHEKKITDIIKEEEASFCKTLAKG---IEKFRKAGQAVQGNTLSGDDAFILWDTY 470
Query: 426 GFPVDLTELMAEEQGLKIDTIGFEKAKQESYEASXXXXXXXASDLIRLNVHELSQLNGDN 485
GFP+DLT+LMAEE+GL +D GF KA +E+ E S A I ++ S L+
Sbjct: 471 GFPLDLTQLMAEERGLLVDVDGFNKAMEEARERSRSAQNKQAGGAIVMDADATSTLHKAG 530
Query: 486 VAKTDDSSKY-------------------------GTENVEATILRIYDGEKFVDSMTEI 520
V+ TDDS KY E+ E+ + IY G F++S +
Sbjct: 531 VSATDDSFKYIWFQVCPFIPENLHVAPEMFLCWRRNEEDHESELKAIYTGSTFLES-SAA 589
Query: 521 GKQYGVILDKTCFYAEQGGQEFDTGKLVIDGEAEFNVDNVQAYNGYVFHTGSLG--DGKL 578
G++L T FYAEQGGQ FDTG L+ FNV NVQ + G+V H G L G++
Sbjct: 590 SDNVGLVLGSTSFYAEQGGQIFDTG-LIEGSFGTFNVCNVQIFGGFVLHIGYLSKETGEV 648
Query: 579 SIGDSIIASYEELRRHPLRNNHTGTHILNFALKEVLGNDVDQKGSLVAPEKLRFDFSHKR 638
S+GD +I + RR + NHT TH+LN+ALKEVLG+ +DQKGS+V PEKLRFDFSH +
Sbjct: 649 SVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGK 708
Query: 639 ALSYEELVEVEKLSNEKIRDNLTVYYKEVALDLAKTISSVRAVFGETYPDPVRVVSIGKA 698
+ E+L +E + N++I+D L V+ KE L AK I +RAVFGE YPDPVRVVSIG+
Sbjct: 709 PVDPEDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEVYPDPVRVVSIGRK 768
Query: 699 VEEVLENPTSEEWQKYSIEFCGGTHVAKTSDIKEFVIVEESGIAKGIRRIVAVSGPEAYE 758
VE++L +P + EW S EFCGGTH+ T + K F ++ E GIAKGIRR+ AV+ A++
Sbjct: 769 VEDLLADPENNEWSLLSSEFCGGTHITNTREAKAFALLSEEGIAKGIRRVTAVTTECAFD 828
Query: 759 VQRIATEFDGELTAVEKLPFSPLKAQKLKELGVRLGQLTISVITKTDLKDKFNKIEKEVK 818
A+ + E+ + S L+ +K+ L R+ I K D++ K ++ EV+
Sbjct: 829 ALNAASLLEREVEDASRAEGSALE-KKVSALKSRVDAAIIPAAKKADIRTKIASLQNEVR 887
Query: 819 DELKSRAKKEIKQTLDDVKHHFD--ANKESSFYVKHIDIPTNAKAITEAINHIKTNSKDK 876
K A++ +K+++ + A+ +F + +D+ +A A+ EA++ + K
Sbjct: 888 KAQKKIAEQNLKKSVKLATEAAESAASDGKTFCIIQLDVGLDAAAVREAVSKV-MEKKGM 946
Query: 877 SIYLFTCNEPDGK 889
SI +F+ +E K
Sbjct: 947 SIMVFSTDESTNK 959
>7297398 [J] KOG0188 Alanyl-tRNA synthetase
Length = 966
Score = 839 bits (2167), Expect = 0.0
Identities = 442/968 (45%), Positives = 603/968 (61%), Gaps = 28/968 (2%)
Query: 10 TAANVRSTFLDYFKSKGHTFVPSSPVIPFDDPTLLFANAGMNQYKPIFLGTVDPSSDFYK 69
TA VR+ +LD+FK + H +V SS IP DDPTLLFANAGMNQ+KPIFLGT DP+S+ K
Sbjct: 5 TAKEVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPNSEMSK 64
Query: 70 LKRATNSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSFGDYFKKEAIEYSWELLTKV 129
R N+QKCIRAGGKHNDL+DVG+D YHHTFFEMLGNWSFGDYFKKE ++WE LT+
Sbjct: 65 WVRVANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQR 124
Query: 130 YGIPGDRLYVTYFEGDEKLGLEPDFEARDLWKSVGVKDDHILPGNAKDNFWEMGEQGPCG 189
+P DRLYVTYF GD GLEPD E + +W +G+K +HILPG+ KDNFWEMGE GPCG
Sbjct: 125 LALPKDRLYVTYFGGDAASGLEPDLECKQMWLDLGLKPEHILPGSMKDNFWEMGETGPCG 184
Query: 190 PCSEVHYDRIGGRNAAHLVNQDDPDVLEIWNNVFIQFNREQDRSLRALPAKHVDTGMGFE 249
PCSE+H+DRIGGR+ LVN DDPDVLEIWN VFIQ+NRE D SL+ LP KH+D GMGFE
Sbjct: 185 PCSELHFDRIGGRSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGFE 244
Query: 250 RLVSVLHDVRSNYDTDVFEPLFNRIQEITGVRSYTGKFGAEDTDGIDTAYRVLADHVRTL 309
RLVSV+ + RSNYDTD+F PLF+ IQ TG Y G+ GA+D DGID AYRVLADH RT+
Sbjct: 245 RLVSVIQNKRSNYDTDLFVPLFDAIQAGTGAPPYQGRVGADDVDGIDMAYRVLADHARTI 304
Query: 310 TFALADGGVPNNEGRGYVXXXXXXXXXXXXXKYMNYPIGNFFSQLSVTLIEQVKDMFPEV 369
T ALADGG P+N GRGYV + +N G FF+ L T+++ + D FPEV
Sbjct: 305 TIALADGGTPDNTGRGYVLRRILRRAVRYATEKLNAKPG-FFATLVNTVVDLLGDAFPEV 363
Query: 370 ARDPSYLFEILDEEEASFAKTLDRGEKLFEKYAEDALKKADKTLDGKQVWRLYDTYGFPV 429
+DP ++ +I++EEE F KTL RG L + E + T+ G WRLYDTYGFPV
Sbjct: 364 KKDPQHIIDIINEEELQFLKTLTRGRNLLNRTIEKLGNQT--TIPGDVAWRLYDTYGFPV 421
Query: 430 DLTELMAEEQGLKIDTIGFEKAKQESYEASXXXXXXXASDLIRLNVHELSQLNGDNVAKT 489
DLT+LMAEE+ LKID G+E AK SY S + I L+VH +SQL V T
Sbjct: 422 DLTQLMAEEKSLKIDMDGYEAAKHNSYVLSQGKGASKIEE-INLDVHAISQLQEQGVPPT 480
Query: 490 DDSSKYGTENV-------------EATILRIYDGEKFVDSMTEIGKQYGVILDKTCFYAE 536
+D+ KY E V + I+ + +FV+ +T G++ G++LDKT FYAE
Sbjct: 481 NDTFKYKYEAVSDERDSAYNYGVCNSKIVALRFENQFVNEITS-GQKAGIVLDKTNFYAE 539
Query: 537 QGGQEFDTGKLV-IDGEA-EFNVDNVQAYNGYVFHTGSLGDGKLSIGDSIIASYEELRRH 594
GGQ +D G LV ++ EA EF VD V GY+ H G + +G L +GD + + RR
Sbjct: 540 SGGQIYDQGALVKVNDEANEFLVDRVYNRGGYILHIGVV-EGTLKVGDELELHIDVERRW 598
Query: 595 PLRNNHTGTHILNFALKEVLGNDVDQKGSLVAPEKLRFDFSHKRALSYEELVEVEKLSNE 654
NH+ TH LN L +VLG D +QKGSLV PEKLRFDF+ K A++ E++ + E+L+ E
Sbjct: 599 LTMKNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLRFDFNSKAAMTIEQVSKTEQLTKE 658
Query: 655 KIRDNLTVYYKEVALDLAKTISSVRAVFGETYPDPVRVVSIGKAVEEVLENPTSEEWQKY 714
+ N+ +Y KE L LAK I +R+VF E YPDPVRV+S G V+E+ +NP SE ++
Sbjct: 659 MVYKNVPIYAKESKLALAKKIRGLRSVFDEVYPDPVRVISFGVPVDELEQNPDSEAGEQT 718
Query: 715 SIEFCGGTHVAKTSDIKEFVIVEESGIAKGIRRIVAVSGPEAYEVQRIATEFDGELTAVE 774
S+EFCGGTH+ ++ I +FVI E IAKGIRRIVA++GPEA + + + F+ E+ ++
Sbjct: 719 SVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAFEQEIVRLK 778
Query: 775 KL-------PFSPLKAQKLKELGVRLGQLTISVITKTDLKDKFNKIEKEVKDELKSRAKK 827
S +++ EL ++ TI + K ++++ ++K + D+ ++
Sbjct: 779 ATIDNDKSGKDSKSHVKEIVELTEQISHATIPYVKKDEMRNLLKGLKKTLDDKERALRAA 838
Query: 828 EIKQTLDDVKHHFDANKESSFYVKHIDIPTNAKAITEAINHIKTNSKDKSIYLFTCNEPD 887
++ K +AN ++ V+ ++ N KA+ A+ +++ D + + +
Sbjct: 839 VSVTVVERAKTLCEANPNATVLVEQLEAFNNTKALDAALKQVRSQLPDAAAMFLSVDADS 898
Query: 888 GKVAHGCYISDAAIAQGVDGSSLAKTVSSSIXXXXXXXXNVFQGMGDKPNGIDSAVAEVE 947
K+ + +A+ +G+ + + VS+++ Q G +D V
Sbjct: 899 KKIFCLSSVPKSAVEKGLKANEWVQHVSATLGGKGGGKPESAQASGTNYEKVDEIVQLAS 958
Query: 948 ALLKERLT 955
+ +L+
Sbjct: 959 KFAQSKLS 966
>CE09768 [J] KOG0188 Alanyl-tRNA synthetase
Length = 968
Score = 827 bits (2136), Expect = 0.0
Identities = 444/961 (46%), Positives = 602/961 (62%), Gaps = 36/961 (3%)
Query: 10 TAANVRSTFLDYFKSKG-HTFVPSSPVIPFDDPTLLFANAGMNQYKPIFLGTVDPSSDFY 68
TA+ VRSTF+++F+ K HT+V SS VIP DDPTLLFANAGMNQ+KP+FLG DP+SD
Sbjct: 5 TASEVRSTFINFFREKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSDLA 64
Query: 69 KLKRATNSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSFGDYFKKEAIEYSWELLTK 128
KLKRA N+QKCIRAGGKHNDL+DVG+D YHHT+FEMLGNWSFGDYFKKE I ++WELLT
Sbjct: 65 KLKRAVNTQKCIRAGGKHNDLDDVGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTT 124
Query: 129 VYGIPGDRLYVTYFEGDEKLGLEPDFEARDLWKSVGVKDDHILPGNAKDNFWEMGEQGPC 188
VYGIP +RLYV+ F GDE G+ D EARD+W+SVGV D+ IL KDNFWEMG+ GPC
Sbjct: 125 VYGIPAERLYVSVFGGDEANGVPADSEARDIWRSVGVPDERILNFGMKDNFWEMGDVGPC 184
Query: 189 GPCSEVHYDRIGGRNAAHLVNQDDPDVLEIWNNVFIQFNREQDRSLRALPAKHVDTGMGF 248
GPCSE+HYDRIG R+A+HLVN DDP V+EIWN VFIQFNRE+ L+ LPAKH+D G+G
Sbjct: 185 GPCSEIHYDRIGNRDASHLVNADDPMVVEIWNLVFIQFNREEGGVLKPLPAKHIDCGLGL 244
Query: 249 ERLVSVLHDVRSNYDTDVFEPLFNRIQEITGVRSYTGKFGAEDTDGIDTAYRVLADHVRT 308
ERL++V+ D SNYDTD+F+P+F I + +GVR+YTG G ED DG+D AYRV+ADHVRT
Sbjct: 245 ERLIAVMQDKTSNYDTDIFQPIFEAIHKGSGVRAYTGFIGDEDKDGVDMAYRVVADHVRT 304
Query: 309 LTFALADGGVPNNEGRGYVXXXXXXXXXXXXXKYMNYPIGNFFSQLSVTLIEQVKDMFPE 368
LT AL+DGG P+N GRGYV + +N G FF+ L +I + + FPE
Sbjct: 305 LTIALSDGGRPDNSGRGYVLRRILRRGVRYASEKLNAQPG-FFASLVPVVISILGETFPE 363
Query: 369 VARDPSYLFEILDEEEASFAKTLDRGEKLFEKYAEDALKKADKTLDGKQVWRLYDTYGFP 428
++RDP + +I+++EE F KTL RG LF++ A +L + T G WRLYDTYGFP
Sbjct: 364 LSRDPVTVMDIINDEEKQFLKTLSRGRVLFQR-AVQSLPEGTMTFPGDVSWRLYDTYGFP 422
Query: 429 VDLTELMAEEQGLKIDTIGFEKAKQESYEASXXXXXXXASDLIRLNVHELSQLNGDNVAK 488
DLT+LMAEE+GL +D FE+A++++ E S D + L+VH L++L V
Sbjct: 423 ADLTQLMAEEKGLSVDNTAFEEARRKAIETSSAGTGKF-RDTLDLDVHALAELQQKGVPT 481
Query: 489 TDDSSKYG-------------TENVEATILRIYDGEKFVDSMTEIGKQYGVILDKTCFYA 535
TDDS KY E IL I KFVD + G++ ++LD+T FYA
Sbjct: 482 TDDSPKYAYTFTGEGSDAVYKFEPCVGKILAIRRDGKFVDQLA-AGEEGAILLDRTNFYA 540
Query: 536 EQGGQEFDTGKL--VIDGEAEFNVDNVQAYNGYVFHTGSLGDGKLSIGDSIIASYEELRR 593
EQGGQ +D G L V D EFNV N Q GY+ GS +G S+GD + ++E R+
Sbjct: 541 EQGGQIYDVGVLTKVNDESNEFNVSNCQVRGGYIVLVGS-AEGSFSVGDQVNERFDEDRK 599
Query: 594 HPLRNNHTGTHILNFALKEVLGNDVDQKGSLVAPEKLRFDFSHKRALSYEELVEVEKLSN 653
+ NHTGTH+LN+AL++VL D DQKGSLVAP+++RFDF++K ++ +++ + E+ +
Sbjct: 600 QLIMKNHTGTHVLNYALRKVLA-DSDQKGSLVAPDRMRFDFTNKAGMTVQQVKKAEEYAQ 658
Query: 654 EKIRDNLTVYYKEVALDLAKTISSVRAVFGETYPDPVRVVSIGKAVEEVLENPTSEEWQK 713
+ I VY K L AK + +RA+F ETYPDPVRVV++G VE++L+NP +EE Q
Sbjct: 659 QLIDTKGQVYAKNSPLGEAKKVKGLRAMFDETYPDPVRVVAVGTPVEQLLQNPDAEEGQN 718
Query: 714 YSIEFCGGTHVAKTSDIKEFVIVEESGIAKGIRRIVAVSGPEA----YEVQRIATEFDGE 769
++EFCGGTH+ S I VI E IAKGIRRIVA++GPEA R+ + E
Sbjct: 719 TTVEFCGGTHLQNVSHIGRIVIASEEAIAKGIRRIVALTGPEAERAIARADRLTARLEEE 778
Query: 770 LTAVEKLPFSPLKAQKLKELGVRLGQLT-------ISVITKTDLKDKFNKIEKEVKDELK 822
+K K K L ++ ++ + K +++K I+K + K
Sbjct: 779 SKHADKKDELLANKDKFKALQKKIQEIVDEANGAQLPYWRKDSIREKAKAIQKTLDGYTK 838
Query: 823 SRAKKEIKQTLDDVKHHFDANKESSFYVKHIDIPTNAKAITEAINHIKTNSKDKSIYLFT 882
++ ++ L + K ++ + V N+KAI A+ +K K++ F+
Sbjct: 839 AQQAAVAEKVLGEAKELAAVAEQPTVLVHVFAANANSKAIDNALKLLKDT---KAVMAFS 895
Query: 883 CNEPDGKVAHGCYISDAAIAQGVDGSSLAKTVSSSIXXXXXXXXNVFQGMGDKPNGIDSA 942
NE GKV + + ++ G+ + V + + Q G+ + +D+A
Sbjct: 896 VNEDSGKVLCLAKVDKSLVSNGLKANEWVNEVCTVLGGKGGGKDANAQLTGENVDKLDAA 955
Query: 943 V 943
V
Sbjct: 956 V 956
>Hs20555071 [J] KOG0188 Alanyl-tRNA synthetase
Length = 985
Score = 600 bits (1548), Expect = e-171
Identities = 346/913 (37%), Positives = 514/913 (55%), Gaps = 39/913 (4%)
Query: 11 AANVRSTFLDYFKSK-GHTFVPSSPVIPFDDPTLLFANAGMNQYKPIFLGTVDPSSDFYK 69
A+ VR+ FL++F+ + GH VPS+ V P DP+LLF NAGMNQ+KPIFLGTVDP S+
Sbjct: 39 ASAVRAAFLNFFRDRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAG 98
Query: 70 LKRATNSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSF-GDYFKKEAIEYSWELLTK 128
+R NSQKC+RAGG HNDLEDVGRD HHTFFEMLGNW+F G+YFK+EA +WELLT+
Sbjct: 99 FRRVANSQKCVRAGGHHNDLEDVGRDLSHHTFFEMLGNWAFGGEYFKEEACNMAWELLTQ 158
Query: 129 VYGIPGDRLYVTYFEGDEKLGLEPDFEARDLWKSVGVKDDHILPGNAKDNFWEMGEQGPC 188
VYGIP +RL+++YF+GD K GL+PD E RD+W S+GV +L ++NFWEMG+ GPC
Sbjct: 159 VYGIPEERLWISYFDGDPKAGLDPDLETRDIWLSLGVPASRVLSFGPQENFWEMGDTGPC 218
Query: 189 GPCSEVHYDRIGGRNAAHLVNQDDPDVLEIWNNVFIQFNREQDRSLRALPAKHVDTGMGF 248
GPC+E+HYD GG A P ++E+WN VF+Q NRE D SL+ LP +HVDTGMG
Sbjct: 219 GPCTEIHYDLAGGVGA--------PQLVELWNLVFMQHNREADGSLQPLPQRHVDTGMGL 270
Query: 249 ERLVSVLHDVRSNYDTDVFEPLFNRIQEITGVRSYTGKFGAEDTDGIDTAYRVLADHVRT 308
ERLV+VL S YDTD+F PL N IQ+ Y G+ G D DTAYRV+ADH+RT
Sbjct: 271 ERLVAVLQGKHSTYDTDLFSPLLNAIQQGCRAPPYLGRVGVADEGRTDTAYRVVADHIRT 330
Query: 309 LTFALADGGVPNNEGRGYVXXXXXXXXXXXXXKYMNYPIGNFFSQLSVTLIEQVKDMFPE 368
L+ ++DG P G V + + P G F L ++E + D +PE
Sbjct: 331 LSVCISDGIFPGMSGPPLVLRRILRRAVRFSMEILKAPPG-FLGSLVPVVVETLGDAYPE 389
Query: 369 VARDPSYLFEILDEEEASFAKTLDRGEKLFEKYAEDALKKADKTLDGKQVW--RLYDTYG 426
+ R+ + + ++ E+EA+F +L+RG ++ ++ L +D + W L G
Sbjct: 390 LQRNSAQIANLVSEDEAAFLASLERGRRIIDRTLR-TLGPSD-MFPAEVAWSLSLCGDLG 447
Query: 427 FPVDLTELMAEEQGLKIDTIGFEKAKQESYEASXXXXXXXASDLIRLNVHELSQLNGDNV 486
P+D+ ELM EE+G+++D+ G E+ QE + + L+VH L +L V
Sbjct: 448 LPLDMVELMLEEKGVQLDSAGLERLAQEEAQHRARQAEPVQKQGLWLDVHALGELQRQGV 507
Query: 487 AKTDDSSKYGTE----------NVEATILRIYDGEKFVDSMTEIGKQYGVILDKTCFYAE 536
TDDS KY EA +L++Y + + G++ G++LD+T FYAE
Sbjct: 508 PPTDDSPKYNYSLRPSGSYEFGTCEAQVLQLYTEDGTAVASVGKGQRCGLLLDRTNFYAE 567
Query: 537 QGGQEFDTGKLVIDGEAE--FNVDNVQAYNGYVFHTGSLGDGKLSIGDSIIASYEELRRH 594
QGGQ D G LV G+ + F V Q G++ H ++ L +GD + +E R
Sbjct: 568 QGGQASDRGYLVRAGQEDVLFPVARAQVCGGFILHE-AVAPECLRLGDQVQLHVDEAWRL 626
Query: 595 PLRNNHTGTHILNFALKEVLGNDVDQKGSLVAPEKLRFDFSHKRALSYEELVEVEKLSNE 654
HT TH+LN+AL++ LG +Q+GS + PE+LR D + + L+ E+L VE E
Sbjct: 627 GCMAKHTATHLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQTPLTPEQLRAVENTVQE 686
Query: 655 KIRDNLTVYYKEVALDLAKTISSVRAVFGETYPDPVRVVSIGKAVEEVLENPTSEEWQKY 714
+ + VY +EV L L + +R++ E YPDPVRVVS+G V L+ P S+ +
Sbjct: 687 AVGQDEAVYMEEVPLALTAQVPGLRSL-DEVYPDPVRVVSVGVPVAHALD-PASQAALQT 744
Query: 715 SIEFCGGTHVAKTSDIKEFVIVEESGIAKGIRRIVAVSGPEAYEVQRIATEFDGEL-TAV 773
S+E C GTH+ +T + + VI+ + ++KG R++AV+G +A + + + E+ A
Sbjct: 745 SVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRLLAVTGEQAQQARELGQSLAQEVKAAT 804
Query: 774 EKLPFSPLKAQKLKELGVRLGQLTISVITKTDLKDKFNKIEKEVKDELKSRA-----KKE 828
E+L + L +G+L +V T + + ++ VK L+ RA K +
Sbjct: 805 ERLSLGSRDVAEALRLSKDIGRLIEAVETAVMPQWQRRELLATVK-MLQRRANTAIRKLQ 863
Query: 829 IKQTLDDVKHHFDANKESSFYVKHIDIPTNAKAITEAINHIKTNSKDKSIYLFTCNEPDG 888
+ Q + + + + V + + + + + + + S+ L + +P G
Sbjct: 864 MGQAAKKTQELLERHSKGPLIVDTVS-AESLSVLVKVVRQLCEQAPSTSVLLLS-PQPMG 921
Query: 889 KVAHGCYISDAAI 901
KV C ++ A+
Sbjct: 922 KVLCACQVAQGAM 934
>ECU02g1490 [J] KOG0188 Alanyl-tRNA synthetase
Length = 864
Score = 517 bits (1332), Expect = e-146
Identities = 336/852 (39%), Positives = 476/852 (55%), Gaps = 92/852 (10%)
Query: 9 WTAANVRSTFLDYFKSKGHTFVPSSPVIPFDDPTLLFANAGMNQYKPIFLGTVDPSSDFY 68
WT +R +FL+YF SK H V SS V+P++D TLLF N+GM Q+K LG +
Sbjct: 3 WTTEKLRQSFLNYFASKSHKIVNSSSVVPYEDDTLLFTNSGMVQFKKNLLG------EKK 56
Query: 69 KLKRATNSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSFGDYFKKEAIEYSWELLTK 128
L+RA + Q+CIRAGGKHNDL+DVG+D+YHHT+FEM+GNWSFGDYFK+E I ++WE L +
Sbjct: 57 DLRRACSVQRCIRAGGKHNDLDDVGKDTYHHTYFEMMGNWSFGDYFKEEGIGFAWEFLVE 116
Query: 129 VYGIPGDRLYVTYFEGDEKLGLEPDFEARDLWKSVGVKDDHILPGNAKDNFWEMGEQGPC 188
V + DRLYVTY++ E D E+ +W+ + I+ + KDNFWEMG+ GPC
Sbjct: 117 VLKLDTDRLYVTYYD-------ELDKESGRIWRKY-LPPSRIIAASYKDNFWEMGDTGPC 168
Query: 189 GPCSEVHYDRIGGRNAAHLVNQDDPDVLEIWNNVFIQFNREQDRSLRALPAKHVDTGMGF 248
GPC+E+HYDRIG R+A+ LVN+DDP+V+EIWN VFI++NR L L K +DTG+G
Sbjct: 169 GPCTEIHYDRIGSRDASRLVNKDDPNVIEIWNIVFIEYNRTTS-GLAPLERKCIDTGIGL 227
Query: 249 ERLVSVLHDVRSNYDTDVFEPLFNRIQEITGVRSYTGKFGAEDTDGIDTAYRVLADHVRT 308
ERL+S+L DV+SNY D F + ++ + Y K AE T D A+RV+ADH RT
Sbjct: 228 ERLLSILMDVKSNYLIDSFSTIIKAMESHCSFK-YNDK--AEST---DVAFRVVADHCRT 281
Query: 309 LTFALADGGVPNNEGRGYVXXXXXXXXXXXXXKYMNYPIGNFFSQLSVTLIEQVKDMFPE 368
+ + D +N+G GYV + + G +L V +
Sbjct: 282 IAVCVYDKVDFSNDGVGYVLRRILRRAVRYAHEVLGLKEG-VLGELVVVAAHAIGIELES 340
Query: 369 VARDPSYLFEILDEEEASFAKTLDRGEKLFEKYAEDALKKADKTLDGKQVWRLYDTYGFP 428
V E +++EE F +TL +G + F + AE + K + G+ ++ LYDTYGFP
Sbjct: 341 V--------ECVNKEELLFMRTLKKGIERFNRLAESSNK-----ISGEDLFLLYDTYGFP 387
Query: 429 VDLTELMAEEQGLKIDTIGFEKAKQESYEASXXXXXXXASDLIRLNVHELSQLNGDNVAK 488
VDLTELMA E+ ++ID FE +Q + EAS S +LN+ ++ +
Sbjct: 388 VDLTELMAVERNIEIDYTNFESCRQRAIEAS------KKSKGTKLNI-DIGMCS--KFPP 438
Query: 489 TDDSSKYGTENVEATILRIYDGEKFVDSMTEI--GKQYGVILDKTCFYAEQGGQEFDTGK 546
TDDS KY V A L GE + +I G + G++ DKTCFYAE GGQ DTGK
Sbjct: 439 TDDSFKYERNGVSAMFLFAVAGEDVITEPCKIPKGIELGIVFDKTCFYAECGGQVGDTGK 498
Query: 547 LVIDGEA----EFNVDNVQAYNGYVFHTGSLGDGKLSIGDSIIASYEELRRHPLRNNHTG 602
++ ++ FNV + QA G+V H G+L DG S + Y ELRR +R NHTG
Sbjct: 499 IIFRDDSGDTGVFNVTDTQAILGFVVHKGAL-DGSASHQALQMYDY-ELRRRIMR-NHTG 555
Query: 603 THILNFALKEVLGNDVDQKGSLVAPEKLRFDFSHKRALSYEELVEVEKLSNEKIRDNLTV 662
TH+LNF L+ V+ Q+GSLV P+KLRFDF R L+ EEL +VE+ N+ I+ V
Sbjct: 556 THLLNFFLRTVI--KTQQRGSLVDPDKLRFDF-EGRKLTNEELEDVERKINDFIKKGAEV 612
Query: 663 YYKEVALDLAKTISSVRAV--FGETYPDPVRVVSI---GKAVEEVLENPTSEEWQKYSIE 717
K V LD + + + V E YP+ VR++++ G ++E+
Sbjct: 613 --KAVILDRRQAMDNPNIVRMQNEEYPENVRIITMQSDGLIIQEM--------------- 655
Query: 718 FCGGTHVAKTSDIKEFVIVEESGIAKGIRRIVAVSGPEAYEVQRIATEFDGELTAVEKLP 777
CGGTHV SDI +F IV E+G++ RRIV V+G +A+E+ + + EL +
Sbjct: 656 -CGGTHVTNVSDIGKFRIVSETGVSANTRRIVGVTGKKAHEL-----DAEAELCLSKLSM 709
Query: 778 FSPLKAQKLKELGVRLGQLTISVITKTDLKDKFNKIEKEVKDELKSRAKKEIKQTLDDVK 837
+ + K L R I V L + K ++E+ + KKE + L K
Sbjct: 710 GNVVNVDKAIPLFYR---QKIEV-----LNQRNRKKDEELSKAQYFKNKKEFLELLAKAK 761
Query: 838 HHFDANKESSFY 849
+ D+N++ + Y
Sbjct: 762 NASDSNEQITIY 773
>CE28096 [J] KOG0188 Alanyl-tRNA synthetase
Length = 793
Score = 467 bits (1201), Expect = e-131
Identities = 283/760 (37%), Positives = 427/760 (55%), Gaps = 56/760 (7%)
Query: 12 ANVRSTFLDYFKSKGHTFVPSSPVIPFD-DPTLLFANAGMNQYKPIFLGTVDPSSDFYKL 70
+ +R +F ++FKSK H + SS VIP + D TLLF NAGMNQ+KP+ L + +
Sbjct: 25 SELRKSFYEFFKSKNHEILRSSSVIPDENDGTLLFTNAGMNQFKPLILSSTES------- 77
Query: 71 KRATNSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSFGDYF-KKEAIEYSWELLTKV 129
+R N QKCIRAGGKHNDL+DVG+D +H TFFEM+GNWSF D F K+EA Y+WE L ++
Sbjct: 78 RRVANIQKCIRAGGKHNDLDDVGKDLHHQTFFEMMGNWSFNDAFSKEEACRYAWEYLVEI 137
Query: 130 YGIPGDRLYVTYFEGDEKLGLEPDFEARDLWKSVGVKDDHILPGNAKDNFWEMGEQGPCG 189
GI DRLYV+YF G EKLGL D E R++WK +GV + ILP A +NFWEMG GPCG
Sbjct: 138 LGINADRLYVSYFGGIEKLGLPEDRECREIWKRIGVSSNRILPFVA-ENFWEMGAAGPCG 196
Query: 190 PCSEVHYDRIGGRNAAHLVNQDDPDVLEIWNNVFIQFNREQDRSLRALPAKHVDTGMGFE 249
PC+E+HYDRIGGR+A+ LVN DD V+EIWN VF+ R+ +R L H+DTGMGFE
Sbjct: 197 PCTEIHYDRIGGRDASRLVNIDD-SVVEIWNIVFMSSVRDSCGQIRHLGKNHIDTGMGFE 255
Query: 250 RLVSVLHDVRSNYDTDVFEPLFNRIQEITGVRSYTGKFGAEDTDGIDTAYRVLADHVRTL 309
RL+SV+ + SN+DTDVF P+ + E+ + YTG + D +R++ADH+R
Sbjct: 256 RLLSVVQNKTSNFDTDVFTPILEKTSEL-AKKQYTGSLDSRQ----DATFRLVADHIRAA 310
Query: 310 TFALADGGVPNNEGRGYVXXXXXXXXXXXXXKYMNYPIGNFFSQLSVTLIEQVKDMFPEV 369
T A++DG VP+ G G++ + S+L + +K+++PE+
Sbjct: 311 TVAISDGAVPDGTGCGFIVRKMMRRAFLQGISKLGIE-RYAMSELVPVVASTMKEVYPEI 369
Query: 370 ARDPSYLFEILDEEEASFAKTLDRGEKLFEKYAEDALKKADKTLDGKQVWRLYDTYGFPV 429
+++ +I ++EEA F KT+D+ +K+F+ A ++ + G++ + L++T+G P+
Sbjct: 370 HDTSTHIRKIFNDEEAQFWKTVDKAKKMFDSVAAES---KSPIISGRKAFNLFETHGLPL 426
Query: 430 DLTELMAEEQGLKIDTIGFEKAKQE----SYEASXXXXXXXASDLIRLNVHELSQLNGDN 485
+T +A G ++D FE+ + E S +AS A D S + +
Sbjct: 427 AVTVELARNIGREVDETEFERCRLEAQKVSQKASQFKLPISADDF-------PSHSDKEK 479
Query: 486 VAKTDDSSKYGTENVEATILRIYDGEKFVDSMTEIGKQYGVILDKTCFYAEQGGQEFDTG 545
+ + KY V+ IL++Y ++ +S+ E + ++L++ FY EQGGQ DTG
Sbjct: 480 YSYVFRNGKYEFPQVKTRILQVYKDQQKAESL-EANDRGFLVLEECQFYGEQGGQTSDTG 538
Query: 546 KLVIDGEAEFNVDNVQAYNGYVFHTGSLGDGKLSIGDS--IIASYEELRRHPLRNNHTGT 603
L+IDG F V+N + G T G L I + +E RR + H+ T
Sbjct: 539 HLLIDGREVFEVENAKKIAGGAV-TVLFGRALLPIRRDLRVEQKLDETRREGVMRAHSAT 597
Query: 604 HILNFALKEVLGNDVDQKGSLVAPEKLRFDFS-HKRALSYEE----LVEVEKLSNEKIRD 658
H+LN+AL++ LG QKGS V ++ RFD+S LS E+ L++ E E I++
Sbjct: 598 HLLNWALQK-LGVGSGQKGSSVDCDRFRFDYSTGDEDLSKEQRTELLIKCEMKMREFIQN 656
Query: 659 NLTVYYKEVALDLAKTISSVRAVFGETY--PDPVRVVSIGKAVEEVLENPTSEEWQKYSI 716
E +L+ AK I ++++ E VRVV++G + +
Sbjct: 657 GGFTEIIETSLEEAKKIENLQSDVKEDRIGGASVRVVALGSGAD-------------VPV 703
Query: 717 EFCGGTHVAKTSDIKEFVIVEESGIAKGIRRIVAVSGPEA 756
E C GTH+ I + I+ + + + +RRI+ ++G EA
Sbjct: 704 ECCSGTHIHDVRVIDDVAIMSDKSMGQRLRRIIVLTGKEA 743
>7295490 [J] KOG0188 Alanyl-tRNA synthetase
Length = 1012
Score = 407 bits (1046), Expect = e-113
Identities = 293/903 (32%), Positives = 424/903 (46%), Gaps = 120/903 (13%)
Query: 10 TAANVRSTFLDYFK-SKGHTFVPSSPVIPFDDPTLLFANAGMNQYKPIFLGTVDPSSDFY 68
TA +R TFLD+F + GH FV SSPV+PF DPT+ F NAGMNQ+K +FLGT
Sbjct: 13 TAREIRKTFLDHFTVNHGHKFVRSSPVVPFCDPTVAFVNAGMNQFKSVFLGTAAAPH--- 69
Query: 69 KLKRATNSQKCIRAGGKHNDLEDVGRDSYHHTFFEMLGNWSFGDYFKKEAIEYSWELLTK 128
KR NSQKC+R GGKHNDL VG D YHHTFFEMLGNWSFGDYFK+EA + ELL
Sbjct: 70 --KRVVNSQKCVRVGGKHNDLSVVGTDGYHHTFFEMLGNWSFGDYFKREACAMALELLRG 127
Query: 129 VYGIPGDRLYVTYFEGDEKLGLEPDFEARDLWKSVGVKDDHILPGNAKDNFWEMGEQGPC 188
Y I RLYVTYF GD+ LG+ D E ++W+S+G ILP DNFWEMG GPC
Sbjct: 128 PYNIDPGRLYVTYFAGDKVLGIPADLECFEIWRSLGFPASRILPFGCADNFWEMGATGPC 187
Query: 189 GPCSEVHYDR---IGG-RNAAHLVNQDDPDVLEIWNNVFIQFNREQDRSLRALPAKHVDT 244
GPC+E+H D +G A LVN D+ E+WN VFIQ+NR D S+ LPA HVDT
Sbjct: 188 GPCTEIHIDHRPDLGSVEQRAKLVNAGRSDLTELWNLVFIQYNRHADGSISQLPAHHVDT 247
Query: 245 GMGFERLVSVLHDVRSNYDTDVFEPLFNRIQEITGVRSYTGKF-GAEDTDGIDTAYRVLA 303
GMGFERL +VL + SNYDTD+F P+F+ IQ+ Y+G F + +DT+YR+LA
Sbjct: 248 GMGFERLTAVLQNKSSNYDTDLFTPIFDGIQQAAKTPVYSGSFPDGGNAAVLDTSYRILA 307
Query: 304 DHVRTLTFALADGGVPNNEGRGYVXXXXXXXXXXXXXKYMN-----YPIGNFFSQLSVTL 358
DH R +T LADG +P+ + K +N + +QL +
Sbjct: 308 DHARMVTACLADGMLPDQNQK----------LRRVLRKALNISEHVFAHDKLLTQLVPIV 357
Query: 359 IEQVKDMFPEVARDPSYLFEILDEEEASFAKTLDRGEKLFEK------------------ 400
+E + + +PE+A + +++ E+ + + K F +
Sbjct: 358 VETLGEAYPEMAAKQQAVIDLICHEQEVYKNLRESSSKAFAEVLMEFPNLDDIDLMECPG 417
Query: 401 ----YAE---DALKKADKTLDGKQVWRLYDTYGFPVDLTELMAEEQGLKID--------T 445
Y E K ++ T+ G +++L DTYG + +AE + + D +
Sbjct: 418 FVPAYRELQMQRCKFSNNTIPGDFLYKLTDTYGLTEESFLKLAELENMNCDLERYRAEVS 477
Query: 446 IGFEKAKQESYEASXXXXXXXASDLIRLNVHELSQLNGDNVAKTDDSSKY---------- 495
+ KAK E + A++ + E + + TD+S KY
Sbjct: 478 LAKLKAKGNQRETAGGSLCDLATE---QRIAEAQAMLTKRLTPTDNSHKYTYSFDKESDS 534
Query: 496 -----------GTENVEATILRIYDGEKFVDSMTEIGKQYGVILDKTCFYAEQGGQEFDT 544
G +A + R G + T++ ++ + FY E GGQ+ D
Sbjct: 535 YQIPPLKTRVLGMLLNDAEVSRT-QGSRIQQPFTDL---ISIVTAGSNFYYESGGQQSDG 590
Query: 545 GKLVI------DGEAEFNVDNVQAYNGYVFHTGSLGDG----KLSIGDSIIASYEELRRH 594
GK+++ D +V V+ N V H L +L+IGD + + +R
Sbjct: 591 GKILVSNHQQPDHPHSLDVIGVKHLNDCVVHICKLSSPTDAFQLAIGDEVELQVDAQQRQ 650
Query: 595 PLRNNHTGTHILNFALKEVLGNDVDQKGSLVAPE--KLRFDFSHKRALSYEELVEVEKLS 652
+HT TH+LN A++ + Q S V+ + KL KR + ++ +E L
Sbjct: 651 LNTCHHTATHLLNAAIRSLFKKVTYQVSSSVSSDQCKLELGLLGKR-IQKTDVQLIEDLI 709
Query: 653 NEKIRDNLTVYYKEVALDLAKTISSVRAVFGETYPDP-VRVVSIGKAVEEVLENPTSEEW 711
N I V + ++ + + V GE YP+ +R+V N S E
Sbjct: 710 NRVICSAAPVEVQLLSAAEVLEQNDITMVPGEVYPEQGLRLV-----------NVESPEL 758
Query: 712 QKYSIEFCGGTHVAKTSDIKEFVIVEESGIAKGIRRIVAVSGPEAYEVQRIATEFDGELT 771
Q S E C GTH TS++ F IV + AV+G A V + A +
Sbjct: 759 QLSSKELCCGTHATNTSELSCFCIVNLKQTNRARFAFTAVAGQAAENVLKTAALLRHRVD 818
Query: 772 AVEKLPFSPLKAQKLKELGVRL-------GQLTISVITKTDLKDKFNKIEKEVKDELKSR 824
+EK F K E ++ + + K D ++ ++ K +KD ++
Sbjct: 819 LLEK-QFQTDKLTNATEAELQTIRHNMLHTDIKLPYAFKMDTLERITEMLKRIKDSSRTT 877
Query: 825 AKK 827
K+
Sbjct: 878 LKE 880
>Hs13376886_2 [R] KOG2105 Predicted metal-dependent hydrolase contains AlaS
domain
Length = 428
Score = 52.0 bits (123), Expect = 4e-06
Identities = 65/264 (24%), Positives = 106/264 (39%), Gaps = 41/264 (15%)
Query: 519 EIGKQYGVILDKTCFYAEQGGQEFDTGKLVIDGEAEFNVDNVQAYNGYVFHTGSLGDGKL 578
E+ + V+L+ T + E GGQ D G + + +V V H L
Sbjct: 52 EVLSGFQVVLEDTVLFPEGGGQPDDRGTI-----NDISVLRVTRRGEQADH---FTQTPL 103
Query: 579 SIGDSIIASYEELRRHPLRNNHTGTHILNFALKEVLGNDVDQKGSLVAPEKLRFDFSHKR 638
G ++ + RR H+G H++ + K + E RF + +
Sbjct: 104 DPGSQVLVRVDWERRFDHMQQHSGQHLITAVADHLF------KLKTTSWELGRFRSAIEL 157
Query: 639 ---ALSYEELVEVEKLSNEKIRDNLTVYYKEVALDLAKTISSVRAVFGETYPD----PVR 691
+++ E++ +E+ NEKIRD L V +E++LD V V G PD P+R
Sbjct: 158 DTPSMTAEQVAAIEQSVNEKIRDRLPVNVRELSLD----DPEVEQVSGRGLPDDHAGPIR 213
Query: 692 VVSIGKAVEEVLENPTSEEWQKYSIEFCGGTHVAKTSDIKEFVIVEESGIAKGIRRIVAV 751
VV+I E V N C GTHV+ SD++ I+ K ++ +
Sbjct: 214 VVNI----EGVDSN------------MCCGTHVSNLSDLQVIKILGTEKGKKNRTNLIFL 257
Query: 752 SGPEAYEVQRIATEFDGELTAVEK 775
SG + + + LTA+ K
Sbjct: 258 SGNRVLKWMERSHGTEKALTALLK 281
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.136 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,563,215
Number of Sequences: 60738
Number of extensions: 2609064
Number of successful extensions: 7525
Number of sequences better than 1.0e-05: 11
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 7437
Number of HSP's gapped (non-prelim): 12
length of query: 956
length of database: 30,389,216
effective HSP length: 116
effective length of query: 840
effective length of database: 23,343,608
effective search space: 19608630720
effective search space used: 19608630720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)