ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0696 good L KOG3657 Replication, recombination and repair Mitochondrial DNA polymerase gamma, catalytic subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0696 231920 235489 1190
(1190 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR330c [L] KOG3657 Mitochondrial DNA polymerase gamma catalytic... 1279 0.0
7298099 [L] KOG3657 Mitochondrial DNA polymerase gamma catalytic... 526 e-149
Hs4505937 [L] KOG3657 Mitochondrial DNA polymerase gamma catalyt... 407 e-113
SPCC24B10.22 [L] KOG3657 Mitochondrial DNA polymerase gamma cata... 298 3e-80
CE25501 [L] KOG3657 Mitochondrial DNA polymerase gamma catalytic... 248 3e-65
>YOR330c [L] KOG3657 Mitochondrial DNA polymerase gamma catalytic subunit
Length = 1280
Score = 1279 bits (3309), Expect = 0.0
Identities = 638/1076 (59%), Positives = 787/1076 (72%), Gaps = 35/1076 (3%)
Query: 17 RVRYFHRSAIVKVEEVEKPRINPVGIQYLSNSLHEQIFPS---KDKYNKFFTEEEKQELI 73
RV++ R K E PRINPVGIQYL SL Q+F S KD+ E+ +L+
Sbjct: 47 RVQFCARWFSTKKNTAEAPRINPVGIQYLGESLQRQVFGSCGGKDEV------EQSDKLM 100
Query: 74 NLSKTFLRNHDLLGKPTNISDPISFELPKLQGRILDEHFQKLGHFASEPYKSMCDNKFKN 133
LSK L++H L GK T I+DPISF LP LQGR LDEHFQK+G F SEPYKS C++KF
Sbjct: 101 ELSKKSLKDHGLWGKKTLITDPISFPLPPLQGRSLDEHFQKIGRFNSEPYKSFCEDKFTE 160
Query: 134 IVPRPKKWLRERGWYRYEPGKEPEKVPYPLEDTLVFDVEVLYKISHFPTLAVALSDKAWY 193
+V RP +WLR+ GW +Y PG P +V YP E+ +VFDVE LY +S +PTLA ALS AWY
Sbjct: 161 MVARPAEWLRKPGWVKYVPGMAPVEVAYPDEELVVFDVETLYNVSDYPTLATALSSTAWY 220
Query: 194 LWCSPFMCDGEGSDNFKHLIPMNTLERPKLIVGHNVGYDRSKVLEEYNFTPSKAYFIDTM 253
LWCSPF+C G D+ LIP+NTL + ++I+GHNV YDR++VLEEYNF SKA+F+DT
Sbjct: 221 LWCSPFIC---GGDDPAALIPLNTLNKEQVIIGHNVAYDRARVLEEYNFRDSKAFFLDTQ 277
Query: 254 SLHVASSGMCSRQRPTYMKKLKRDEEVAQLNAENDDLPPIADVDEDSPWINKSSANSLKD 313
SLH+AS G+CSRQRP +MK K+ E E++ P I+ D D PW+N S+ NSLKD
Sbjct: 278 SLHIASFGLCSRQRPMFMKNNKKKEA----EVESEVHPEISIEDYDDPWLNVSALNSLKD 333
Query: 314 VARFHCNIKMSKEARESFATLDKFEIINNFDSMVEYCAFDVEATSKVFDEVFPKFLQKCP 373
VA+FHC I + K R+ FA+ DK II NF +V YCA DV ATS+VFDE+FP FL+KCP
Sbjct: 334 VAKFHCKIDLDKTDRDFFASTDKSTIIENFQKLVNYCATDVTATSQVFDEIFPVFLKKCP 393
Query: 374 HPVSFGALRFLSTSILPTRVGKWEKYLNSSETLFQDNKAKIEDKIVKIVEDTLQLKNQTE 433
HPVSF L+ LS ILPT++ W YLNSSE+L+Q +K +IE KIV+I++D + LK++ +
Sbjct: 394 HPVSFAGLKSLSKCILPTKLNDWNDYLNSSESLYQQSKVQIESKIVQIIKDIVLLKDKPD 453
Query: 434 LIKNDPWLKQLDWTAVPVKYTKSGEIRKNQKLPGYPEWYRSLFPSKSXXXXXXXXXXXXV 493
DPWL QLDWT P++ TK G K QKLPG+PEWYR LFPSK +
Sbjct: 454 FYLKDPWLSQLDWTTKPLRLTKKGVPAKCQKLPGFPEWYRQLFPSKDTVEPKITIKSRII 513
Query: 494 PLFFKLTWEDCPVVYTNSQGWCFRCDNSRVEEILAKNYVKAVEVDDYHEEDTT------- 546
P+ FKL+WE+ PV+++ GWCF + +VE AKNYV A V EE T
Sbjct: 514 PILFKLSWENSPVIWSKESGWCFNVPHEQVETYKAKNYVLADSVSQEEEEIRTHNLGLQC 573
Query: 547 ---LFKIPHPNGPEFNCSTLLSKPFMHYFEKGVLKSQSKLAHDALQINASGAYWMSARER 603
LFK+PHPNGP FNC+ LL+K + H+FEKGVLKS+S+LAH ALQIN+SG+YWMSARER
Sbjct: 574 TGVLFKVPHPNGPTFNCTNLLTKSYNHFFEKGVLKSESELAHQALQINSSGSYWMSARER 633
Query: 604 IMSQHVVSVNDFKSEF---NAKTPF--DKDLDVGIILPKLVPMGTVTRRSVENTWLTASN 658
I SQ VV F +EF +AK+ +K D+ II+PK+VPMGT+TRR+VEN WLTASN
Sbjct: 634 IQSQFVVPSCKFPNEFQSLSAKSSLNNEKTNDLAIIIPKIVPMGTITRRAVENAWLTASN 693
Query: 659 AKKNRIGSELKCNVEAPPGYTFVGADVDSEELWIASLVGDSIFDIHGATAIGWMCLEGTK 718
AK NRIGSELK V+APPGY FVGADVDSEELWIASLVGDSIF++HG TAIGWMCLEGTK
Sbjct: 694 AKANRIGSELKTQVKAPPGYCFVGADVDSEELWIASLVGDSIFNVHGGTAIGWMCLEGTK 753
Query: 719 SLGTDLHSKTAHILGCSRDEAKIFNYGRIYGAGVKFAAQLLKKFNPMLSEDEAKKTAERL 778
+ GTDLH+KTA ILGCSR+EAKIFNYGRIYGAG KFA+QLLK+FNP L+++E KK A +L
Sbjct: 754 NEGTDLHTKTAQILGCSRNEAKIFNYGRIYGAGAKFASQLLKRFNPSLTDEETKKIANKL 813
Query: 779 YENTKGKKQRSTIFKTFWYGGSESILFNKLESIAEQDEPKTPVLGAGITYSLMKKNLGKD 838
YENTKGK +RS +FK FWYGGSESILFNKLESIAEQ+ PKTPVLG GITYSLMKKNL +
Sbjct: 814 YENTKGKTKRSKLFKKFWYGGSESILFNKLESIAEQETPKTPVLGCGITYSLMKKNLRAN 873
Query: 839 TFLPSRINWVIQSSGVDYLHILCCSMNYLIEKYSIDARLMISIHDEIRYIVSEKDKYRIT 898
+FLPSRINW IQSSGVDYLH+LCCSM Y+I+KY+++ARL ISIHDEIR++VSEKDKYR
Sbjct: 874 SFLPSRINWAIQSSGVDYLHLLCCSMEYIIKKYNLEARLCISIHDEIRFLVSEKDKYRAA 933
Query: 899 LALQISNLWTRSYFSEQMCINDLPQNCAFFSAVDVDRVMRKEVDMDCITPSNPNAIPHGE 958
+ALQISN+WTR+ F +QM IN+LPQNCAFFS VD+D V+RKEV+MDCITPSN AIPHGE
Sbjct: 934 MALQISNIWTRAMFCQQMGINELPQNCAFFSQVDIDSVIRKEVNMDCITPSNKTAIPHGE 993
Query: 959 SLGILDILKITNGYLGEPTDAVD--VSQFPYRHRESVFRQYNKRYSKDFLRYSLAMQIQD 1016
+L I +L +N LG+P +D VSQ+ Y +RE VF +YNK Y+ +FL+Y LAMQ+Q
Sbjct: 994 ALDINQLLDKSNSKLGKPNLDIDSKVSQYAYNYREPVFEEYNKSYTPEFLKYFLAMQVQS 1053
Query: 1017 TKWKIDEIEKSYLRAMEEAKFRLVDNEV-MTMADYIRGNTPDGKPKKQSIMSDEVM 1071
K ++ +E YLR ++ N ++ DYI+ + GK K IM +
Sbjct: 1054 DKRDVNRLEDEYLRECTSKEYARDGNTAEYSLLDYIK-DVEKGKRTKVRIMGSNFL 1108
>7298099 [L] KOG3657 Mitochondrial DNA polymerase gamma catalytic subunit
Length = 1145
Score = 526 bits (1355), Expect = e-149
Identities = 377/1162 (32%), Positives = 558/1162 (47%), Gaps = 230/1162 (19%)
Query: 7 LLQKGAGSIRRVRYFHRSAIV--------KVEEVEKPRI----------NPVGIQYLSNS 48
L++K A + R Y S + KV + +KP N V +Q +S +
Sbjct: 5 LIRKYASKVSREHYASSSVKIFRRVKPPQKVNKPKKPENVENGPTEYAENLVKVQMISRN 64
Query: 49 LHEQIFPSKDKYNKFFTEEEKQELINLSKTFLRNHDL-LGKPTNISDPISFELPKLQGRI 107
LH Q+FP + E++ + K LR H + + +SD + +LP L+G
Sbjct: 65 LHAQLFPQAPRS----ISEQQVASAKVYKDELRRHGVDIESSAPVSD-VQLKLPALRGAN 119
Query: 108 LDEHFQKLGHFASEPYKSMCDN--KFKNIVPRPKKWLRERGWYRYEPGK-EPEKVPYPLE 164
++EHF + +PY+ + + + + RPK+W GW Y+P V +PLE
Sbjct: 120 IEEHFHNIAKEQVQPYEELLLPLVQCEQLPKRPKRWAFHTGWTAYDPEDGTATPVDHPLE 179
Query: 165 DTLVFDVEVLYKISHFPTLAVALSDKAWYLWCSPFMC------------DGEGSDNFKH- 211
LVFDVEV P LA A+S K WY W S + D + H
Sbjct: 180 KGLVFDVEVCVSEGQAPVLATAVSTKRWYSWVSSKLTKHRLSVEKLEPLDVDTDSERPHY 239
Query: 212 ----LIPMNTLERPKLIVGHNVGYDRSKVLEEYNFTPSKAYFIDTMSLHVASSGMCSRQR 267
LIP+ T P L+VGHNV YDR+++ E+Y + F+DTMSLH+ SG+ S QR
Sbjct: 240 TTDELIPLGTTG-PGLVVGHNVSYDRARLKEQYLTEDTGTRFVDTMSLHMCVSGVTSYQR 298
Query: 268 PTYMKKLKRDEEVAQLNAENDDLPPIADVDEDSPWINKSSANSLKDVARFHCN-IKMSKE 326
M K K++ P A ED W+ +SS NSL +V R +C +SKE
Sbjct: 299 A--MLKSKKE--------------PAA---EDLGWLEQSSLNSLVEVHRLYCGGDTLSKE 339
Query: 327 ARESFATLDKFEIINNFDSMVEYCAFDVEATSKVFDEVFPKFLQKCPHPVSFGALRFLST 386
R F ++ +F S+ YCA DVEAT ++ ++P + ++ PHP S + + +
Sbjct: 340 PRNIFVEGTLEQVRQSFQSLTNYCASDVEATHRILRVLYPLYAERFPHPASLAGMLEMGS 399
Query: 387 SILPTRVGKWEKYLNSSETLFQDNKAKIEDKIVKIVEDTLQLKNQTELIKNDPWLKQLDW 446
+ LP WE+Y+ ++ ++D + + + + E+ L + +N WL DW
Sbjct: 400 AYLPVN-SNWERYIREAQLTYEDLSIEAKYHLGRRAEEACSLLLDDQYRQN-LWLWDEDW 457
Query: 447 TAVPVKYTK--------------SGEIRKNQKL---------------------PGYPEW 471
+ +K + SG + ++L PGYP W
Sbjct: 458 SVQELKLKQPPKRKPLPTVELKDSGNTPEERRLQAKFQHLYDQQALLPARRPLLPGYPLW 517
Query: 472 YRSLF---PSK-------------SXXXXXXXXXXXXVPLFFKLTWEDCPVVYTNSQGWC 515
YR L P+K S P L WE P+ Y QGW
Sbjct: 518 YRKLCRKPPAKRADEILEDDEEPWSPGASEISTGMQIAPKLLSLCWEGYPLHYEREQGWG 577
Query: 516 F----RCDNSRV-----EEILA-----------------------------------KNY 531
F R D+ V E++LA ++Y
Sbjct: 578 FLVPFRSDSEGVDRLPMEQLLAHCPVPEFARLSASKAESDMAFDMLPGQVEQHLGKREHY 637
Query: 532 VKAVEVDDYHE--------------EDTTLF-KIPHPNGPEFNCSTLLSKPFMHYFEKGV 576
K + E +D F K+PH NGP F LSK F++ F + V
Sbjct: 638 KKLSQKQQRLETQYQGSGVWCNKVLDDCCFFLKLPHKNGPSFRVGNPLSKDFLNKFAENV 697
Query: 577 LKS---QSKLAHDALQINASGAYWMSARERIMSQHVVSVND--FKSEFNAKTPFDKDLDV 631
L S + A + I +YW + R+RIM Q VV ++ +EF + + +
Sbjct: 698 LSSGDPSCQAAARVIDIARMMSYWRNNRDRIMGQMVVWLDSQQLPNEFTGEKC--QPIAY 755
Query: 632 GIILPKLVPMGTVTRRSVENTWLTASNAKKNRIGSELKCNVEAPPGYTFVGADVDSEELW 691
G I P++V GT+TRR++E TW+TASN++ +R+GSEL+ V+APPGY VGADVDS+ELW
Sbjct: 756 GAICPQVVACGTLTRRAMEPTWMTASNSRPDRLGSELRSMVQAPPGYRLVGADVDSQELW 815
Query: 692 IASLVGDSIF-DIHGATAIGWMCLEGTKSLGTDLHSKTAHILGCSRDEAKIFNYGRIYGA 750
IAS++GD+ HGAT +GWM L G+KS G+D+HS TA +G SRD AK+ NY RIYGA
Sbjct: 816 IASVLGDAYACGEHGATPLGWMTLSGSKSNGSDMHSITAKAVGISRDHAKVINYARIYGA 875
Query: 751 GVKFAAQLLKKFNPMLSEDEAKKTAERLYENTKGKK------------------------ 786
G FA LL++FNP S EAK A +++ TKGK+
Sbjct: 876 GQLFAETLLRQFNPTFSASEAKAKAMKMFSITKGKRVYRLREEFHDELEDRAYSSYEASR 935
Query: 787 ----QRSTIFKTF----WYGGSESILFNKLESIAEQDEPKTPVLGAGITYSLMKKNLGKD 838
+ T+ + F W GG+ES +FN+LE IA +P+TP LG ++ +L + + G +
Sbjct: 936 LAIQRNRTLAEVFHRPNWQGGTESAMFNRLEEIATGSQPRTPFLGGRLSRAL-EADTGPE 994
Query: 839 T---FLPSRINWVIQSSGVDYLHILCCSMNYLIEKYSIDARLMISIHDEIRYIVSEKDKY 895
FLP+RINWV+QS VD+LH++ SM +L+ + R +S HDE+RY+V E+
Sbjct: 995 QEQRFLPTRINWVVQSGAVDFLHLMLVSMRWLMGSH---VRFCLSFHDELRYLVKEELSP 1051
Query: 896 RITLALQISNLWTRSYFSEQMCINDLPQNCAFFSAVDVDRVMRKEVDMDCITPSNPN--- 952
+ LA+ I+NL TRS+ ++ + DLP + AFFS+V+VD V+RKE MDC TPSNP+
Sbjct: 1052 KAALAMHITNLMTRSFCVSRIGLQDLPMSVAFFSSVEVDTVLRKECTMDCKTPSNPHGLR 1111
Query: 953 ---AIPHGESLGILDILKITNG 971
I G+SL + + ++ G
Sbjct: 1112 IGYGIQPGQSLSVAEAIEKAGG 1133
>Hs4505937 [L] KOG3657 Mitochondrial DNA polymerase gamma catalytic subunit
Length = 1239
Score = 407 bits (1047), Expect = e-113
Identities = 229/483 (47%), Positives = 307/483 (63%), Gaps = 58/483 (12%)
Query: 548 FKIPHPNGPEFNCSTLLSKPFMHYFEKGVLKSQSKLAHD--ALQINASGAYWMSARERIM 605
FK+PH +G N + +K F+ E G L++ A AL+IN ++W +A +RI
Sbjct: 750 FKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRIS 809
Query: 606 SQHVVSV--NDFKSEFNAKTPFDKDLDVGIILPKLVPMGTVTRRSVENTWLTASNAKKNR 663
SQ VV + + +D++ G ILP++V GT+TRR+VE TWLTASNA+ +R
Sbjct: 810 SQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDR 869
Query: 664 IGSELKCNVEAPPGYTFVGADVDSEELWIASLVGDSIF-DIHGATAIGWMCLEGTKSLGT 722
+GSELK V+APPGYT VGADVDS+ELWIA+++GD+ F +HG TA GWM L+G KS GT
Sbjct: 870 VGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGT 929
Query: 723 DLHSKTAHILGCSRDEAKIFNYGRIYGAGVKFAAQLLKKFNPMLSEDEAKKTAERLYENT 782
DLHSKTA +G SR+ AKIFNYGRIYGAG FA +LL +FN L++ EA + A+++Y T
Sbjct: 930 DLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAAT 989
Query: 783 KG-----------------------------------KKQRSTIFKT-----------FW 796
KG K QR T K+ W
Sbjct: 990 KGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAW 1049
Query: 797 YGGSESILFNKLESIAEQDEPKTPVLGAGITYSLMKKNLGKDTFLPSRINWVIQSSGVDY 856
GG+ES +FNKLESIA D P+TPVLG I+ +L + + ++ F+ SR+NWV+QSS VDY
Sbjct: 1050 KGGTESEMFNKLESIATSDIPRTPVLGCCISRAL-EPSAVQEEFMTSRVNWVVQSSAVDY 1108
Query: 857 LHILCCSMNYLIEKYSIDARLMISIHDEIRYIVSEKDKYRITLALQISNLWTRSYFSEQM 916
LH++ +M +L E+++ID R ISIHDE+RY+V E+D+YR LALQI+NL TR F+ ++
Sbjct: 1109 LHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKL 1168
Query: 917 CINDLPQNCAFFSAVDVDRVMRKEVDMDCITPSNPN------AIPHGESLGILDILKITN 970
+NDLPQ+ AFFSAVD+DR +RKEV MDC TPSNP IP GE+L I I+++T
Sbjct: 1169 GLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTK 1228
Query: 971 GYL 973
G L
Sbjct: 1229 GSL 1231
Score = 229 bits (584), Expect = 2e-59
Identities = 167/564 (29%), Positives = 243/564 (42%), Gaps = 98/564 (17%)
Query: 36 RINPVGIQYLSNSLHEQIFPSKDKYNKFFTEEEKQELINLSKTFLRNHDLLGKPTNISDP 95
R NP+ IQ LS LHEQIF E + + S L+ H L G+P
Sbjct: 70 RHNPLDIQMLSRGLHEQIFGQGG-------EMPGEAAVRRSVEHLQKHGLWGQPAVPLPD 122
Query: 96 ISFELPKLQGRILDEHFQKLGHFASEPYKSMCDNKFK-NIVPRPKKWLRERGWYRYEPGK 154
+ LP L G LD+HF+ L S PY + + + P+P W GW RY P
Sbjct: 123 VELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEG 182
Query: 155 EPEKVPYPLEDTLVFDVEVLYKISHFPTLAVALSDKAWYLWCSPFMCDGEGSDNFK---- 210
E V P E LVFDVEV PTLAVA+S AWY WCS + + S +
Sbjct: 183 EAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPA 242
Query: 211 HLIPMNTLE----------RPKLIVGHNVGYDRSKVLEEYNFTPSKAYFIDTMSLHVASS 260
LIP+ + +L+VGHNV +DR+ + E+Y S+ F+DTMS+H+A S
Sbjct: 243 DLIPLEVPTGASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAIS 302
Query: 261 GMCSRQRPTYMKKLKRDEEVAQLNAENDDL-------PPIADVDEDSPWINKSSANSLKD 313
G+ S QR ++ + +V + P I+ D W++ SS NSL +
Sbjct: 303 GLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGPAISSWD----WLDISSVNSLAE 358
Query: 314 VARFHC-NIKMSKEARESFATLDKFEIINNFDSMVEYCAFDVEATSKVFDEVFPKFLQKC 372
V R + + KE RE F +I NF +++YCA DV AT +VF + P FL++C
Sbjct: 359 VHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERC 418
Query: 373 PHPVSFGALRFLSTSILPTRVGKWEKYLNSSETLFQDNKAKIEDKIVKIVEDTLQLKNQT 432
PHPV+ + + S LP WE+YL ++ +++ + +++ ++ + D QL +
Sbjct: 419 PHPVTLAGMLEMGVSYLPVN-QNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLS-G 476
Query: 433 ELIKNDPWLKQLDWTAVPVKYTKSGEIRKN----QKLP---------------------- 466
E K DPWL L+W K K+ +++K KLP
Sbjct: 477 ERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEE 536
Query: 467 -------------------------------GYPEWYRSLF-----PSKSXXXXXXXXXX 490
G+P WYR L P+ +
Sbjct: 537 EEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQM 596
Query: 491 XXVPLFFKLTWEDCPVVYTNSQGW 514
P LTW+ P+ Y+ GW
Sbjct: 597 RVTPKLMALTWDGFPLHYSERHGW 620
>SPCC24B10.22 [L] KOG3657 Mitochondrial DNA polymerase gamma catalytic subunit
Length = 416
Score = 298 bits (763), Expect = 3e-80
Identities = 161/379 (42%), Positives = 219/379 (57%), Gaps = 18/379 (4%)
Query: 36 RINPVGIQYLSNSLHEQIFPSKDKYNKFFTEEEKQELINLSKTFLRNHDLLGKPTNISDP 95
RINPVG+QYLS +L Q+FP ++ + Q ++L+K L H LL K T
Sbjct: 43 RINPVGVQYLSPALQNQVFPQQNT-------QISQLHLDLAKFHLAKHQLLNKETIKLPS 95
Query: 96 ISFELPKLQGRILDEHFQKLGHFASEPYKSMCDNKFKNIVP-RPKKWLRERGWYRYEPGK 154
+F LP LQG+ + EHF +G +EP+ S K P +PK W R+ GW +Y
Sbjct: 96 FNFRLPPLQGKTISEHFYNIGLEFAEPHLSKAIKFSKIDTPVQPKTWKRQPGWTKYAKDG 155
Query: 155 EPEKVPYPLEDTLVFDVEVLYKISHFPTLAVALSDKAWYLWCSPFMCDGEGSDNFKHLIP 214
VPYP D +VFDVEVLYK+S F +A A+S+ AWY W SP++ S+N + LIP
Sbjct: 156 SISCVPYPDSDCMVFDVEVLYKVSPFAVVATAVSEDAWYCWLSPWLLGK--SENDRQLIP 213
Query: 215 MNTLERPKLIVGHNVGYDRSKVLEEYNFTPSKAYFIDTMSLHVASSGMCSRQRPTYMKKL 274
N + L VGHNV +DR ++ EEYN S+ F+DTMSLHVA+ GMCSRQ+PT+ K
Sbjct: 214 SNP--KGALFVGHNVSFDRQRIREEYNIKSSRNVFLDTMSLHVATHGMCSRQKPTWFKAR 271
Query: 275 KRDEEVAQLNAENDDLPPIADVD-----EDSPWINKSSANSLKDVARFHCNIKMSKEARE 329
K DD D D + PW+ SS NSLKDVA+FHCNI + K R+
Sbjct: 272 KAYIRSQSTETSEDDDSSSFDDDYQNYLKQEPWLAHSSVNSLKDVAKFHCNITLDKSKRD 331
Query: 330 SFATLDKFEIINNFDSMVEYCAFDVEATSKVFDEVFPKFLQKCPHPVSFGALRFLSTSIL 389
FA+L+K I+ + ++ YCA D +T +VF +VFP+FL+ CPHP +F A+ L + L
Sbjct: 332 DFASLEKEPILQKLNELITYCAHDTYSTHQVFKKVFPQFLEVCPHPATFSAMLSLGSVFL 391
Query: 390 PTRVGKWEKYLNSSETLFQ 408
P W +Y+N E +Q
Sbjct: 392 PVN-HSWTRYINGVEEQYQ 409
>CE25501 [L] KOG3657 Mitochondrial DNA polymerase gamma catalytic subunit
Length = 1072
Score = 248 bits (634), Expect = 3e-65
Identities = 211/783 (26%), Positives = 336/783 (41%), Gaps = 143/783 (18%)
Query: 100 LPKLQGRILDEHFQKLGHFASEPYKSMCDNKF-------KNIVPRPKK---WLRERGWYR 149
LP L + +HF L + YK + + KN++ K W + GW R
Sbjct: 60 LPPLVADNVVDHFGVLAEQQTRKYKELLEKACEFDLETAKNVLEHIDKTDGWHYKTGWTR 119
Query: 150 Y--EPGKEPEKVPYPLEDTLVFDVEVLYKISHFPTLAVALSDKAWYLWCSP---FMCDGE 204
Y + PE + +P + L FD+E++ + PTLA+AL AWY WCS + +
Sbjct: 120 YPFSTSEPPETIDFPRDSILFFDIELVVRDGTLPTLAIALGRDAWYGWCSDRLIYESEIP 179
Query: 205 GSDNFKHLIPMNTLERPKLIVGHNVGYDRSKVLEEY-NFTPSKAYFIDTMSLHVASSGMC 263
LIP+ + K+I+GHNVG+DR++ E Y + SK F+DTMS+ + GM
Sbjct: 180 EIPTKADLIPIGEIGMEKVIIGHNVGFDRARCREAYQSINGSKIRFMDTMSMSIPMYGMA 239
Query: 264 SRQRPTYMKKLKRDEEVAQLNAENDDLPPIADVDEDSPWINKSSANSLKDV-------AR 316
Q+ Y + E +D + D + W + S NSL V
Sbjct: 240 DHQQSLY----------EMYDVETND----SHSDWMNAWKGRVSKNSLVAVHDHLYPDKA 285
Query: 317 FHCNIKMSKEARESFATLDKFEIINNFDSMVEYCAFDVEATSKVFDEVFPKFLQKCPHPV 376
+ K R SF +I +F ++ YCA D ++++ ++P+F+++ PHP
Sbjct: 286 INAEGFSKKTMRASFVKDPIEQIREDFQPLMSYCARDNILCAEIYFRLWPEFIKRFPHPA 345
Query: 377 SFGALRFLSTSILPTRVGKWEKYLNSSETLFQDNKAKIEDKIVKIVE-DTLQLKNQTELI 435
+ + + LP W+ + + + K KI++ +L ++ E I
Sbjct: 346 TLSGMLNMGNVYLPIN-SYWKMFYEKNVQTCEQKKTAATRKIIESARLVAKRLDDEGEEI 404
Query: 436 ---KNDPWLKQLDWTAVPVKYTKSGEIRKNQKLPGYPEWYRSLFPSKS--------XXXX 484
KND W+ DWT NQK + EW+ LF ++S
Sbjct: 405 GPEKNDVWMWHHDWTF-------------NQKQSNF-EWFNKLFKARSFVNLSLDEVDSH 450
Query: 485 XXXXXXXXVPLFFKLTWEDCPVVYTNSQGWCFRCDNSRVEEILAKNYVKAVEVDDYHEED 544
+P F + P+ T S+GW F N + E KA++ ++HE D
Sbjct: 451 HIALKSHLIPAIFGFVFGPFPLFKTRSKGWGFLVPNWKPVE-------KALQDPNFHEID 503
Query: 545 TTL-------------------------------------------------FKIPHPNG 555
+ +++ HP+G
Sbjct: 504 AKIDFKPDSAVKKFPLRSFYETVQNNVYMLGELPISPDRKGFELDEAGLVRFYQLDHPSG 563
Query: 556 PEFNCSTLLSKPFMHYFEKGVLK-----SQSKLAHDALQINASGAYWMSARERIMSQHVV 610
E N L+K F ++ VL+ + D++Q + +W S +R S+ +
Sbjct: 564 -EGNVGDPLTKHFAKDLKELVLRPTRYEEYFDVVLDSIQ---TTQFWTSYSDRYCSEVAI 619
Query: 611 SVNDFKSEFNAKTPFDKDLDVGIILPKLVPMGTVTRRSVENTWLTASNAKKNR-IGSELK 669
+ E +T + ++ G I +VP GT++RRSV W+T +N IG+ +K
Sbjct: 620 ----WSPEATWRTAENLEMIDGAIAAAVVPAGTISRRSVHKLWVTLTNQSTGHVIGTGIK 675
Query: 670 CNVEAPPGYTFVGADVDSEELWIASLVGDSIFD--------IHGATAIGWMCLEGTKSLG 721
V+AP GY VGADVDS+E W+A+L GD+ + + G TA M L G+KS
Sbjct: 676 AMVQAPAGYRLVGADVDSQEQWLAALYGDASAEKRLPLEKRVAGKTAFSNMMLAGSKSDN 735
Query: 722 TDLHSKTAHILGCSRDEAKIFNYGRIYGAGVKFAAQLLKKFNPMLSEDEAKKTAERLYEN 781
TDLHS A L SR+ AK+ NY R+YG+G A + L + L + EA+ TA +L++
Sbjct: 736 TDLHSVVASQLKISRNHAKVLNYARLYGSGETHAGKHLMRVGG-LKQSEAESTASQLFKL 794
Query: 782 TKG 784
TKG
Sbjct: 795 TKG 797
Score = 151 bits (381), Expect = 7e-36
Identities = 93/230 (40%), Positives = 130/230 (56%), Gaps = 16/230 (6%)
Query: 752 VKFAAQLLKKFNPMLS-EDEAKKTAERLYENTKGKKQRSTIFKTFWYGGSESILFNKLES 810
V+F LL ++ +L+ E +YEN ++ + GG ES FN LE+
Sbjct: 850 VRFEDWLLSHYSSLLNGSSEPDSLIYSIYENPDEPRR-------LFVGGYESSTFNFLET 902
Query: 811 IAEQDEPKTPVLGAGITYSLMKKNLGKDT-------FLPSRINWVIQSSGVDYLHILCCS 863
A + +TP+LG I SL K G + S +NW++QSS VD+LH+L S
Sbjct: 903 SAAAHDLRTPILGCQIADSLGKLPEGTPDSAYFDRKYKRSVMNWIVQSSAVDFLHLLLVS 962
Query: 864 MNYLIEKYSIDARLMISIHDEIRYIVSEKDKYRITLALQISNLWTRSYFSEQMCINDLPQ 923
M +L + Y IDAR +ISIHDE+RY+ E D R+ LALQ+SNL R+Y S+++ I LP
Sbjct: 963 MQWLCDTYKIDARFVISIHDEVRYMCKEPDAPRLALALQLSNLLVRAYISQRVGICQLPN 1022
Query: 924 NCAFFSAVDVDRVMRKEVDMDCITPSNPNAIPHGESLGILDILKITNGYL 973
AFFS VD D V+RKEVD + I P + I G + + D+LK+T G L
Sbjct: 1023 TVAFFSQVDCDTVLRKEVDTESINPDG-SKIADGVAWTVDDLLKLTGGKL 1071
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,114,878
Number of Sequences: 60738
Number of extensions: 3302459
Number of successful extensions: 8669
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 8613
Number of HSP's gapped (non-prelim): 13
length of query: 1190
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1072
effective length of database: 23,222,132
effective search space: 24894125504
effective search space used: 24894125504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)