ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0733 good L KOG0219 Replication, recombination and repair Mismatch repair ATPase MSH2 (MutS family)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0733 245783 248650 956
(956 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL090w [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 1186 0.0
Hs4557761 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 631 e-180
7298155 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 441 e-123
CE21000 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 371 e-102
SPBC24C6.12c [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 349 1e-95
SPBC19G7.01c [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 315 3e-85
SPCC285.16c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 236 1e-61
ECU03g0540 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 234 5e-61
Hs20535615 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 214 7e-55
Hs4505251 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 213 1e-54
Hs4504191 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 213 1e-54
SPAC8F11.03 [L] KOG0218 Mismatch repair MSH3 212 2e-54
YDR097c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 210 7e-54
YCR092c [L] KOG0218 Mismatch repair MSH3 209 2e-53
At3g18525 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 207 6e-53
At4g02070 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 203 1e-51
Hs4505249 [L] KOG0218 Mismatch repair MSH3 202 2e-51
CE28985 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 199 2e-50
CE24714 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 179 2e-44
Hs21361940 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 178 4e-44
YDL154w [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 176 1e-43
Hs4505253 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 176 2e-43
ECU10g0710 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 165 3e-40
At4g25540 [L] KOG0218 Mismatch repair MSH3 157 1e-37
At4g17380 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 154 5e-37
CE26678 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 149 3e-35
YFL003c [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 145 4e-34
At3g20475 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 108 3e-23
At3g24320 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 91 7e-18
CE04858 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 72 3e-12
7294307 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 69 5e-11
>YOL090w [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 964
Score = 1186 bits (3067), Expect = 0.0
Identities = 594/971 (61%), Positives = 764/971 (78%), Gaps = 25/971 (2%)
Query: 2 SSRPDLKFSDIAEERGFYKRFLQLPQRSQNTIRLVDKSDYYIVVGDDALFVADQVYHTSS 61
S+RP+LKFSD++EER FYK++ LP++ TIRLVDK DYY V+G DA+FVAD VYHT S
Sbjct: 3 STRPELKFSDVSEERNFYKKYTGLPKKPLKTIRLVDKGDYYTVIGSDAIFVADSVYHTQS 62
Query: 62 VLKDCKIDPSTLRQFDLQEPLKYVTMSIQIVGNLLKTSLLELGKKIEIYDRNWKLLKTAS 121
VLK+C++DP T + F EP KYVT+S+Q++ LLK LL+LG K+EIYD+ WKL+K+AS
Sbjct: 63 VLKNCQLDPVTAKNF--HEPTKYVTVSLQVLATLLKLCLLDLGYKVEIYDKGWKLIKSAS 120
Query: 122 PGNLEQVDDLIVGSVETNIVLASLKLNFNGTAASNYCTIGVSFVDNTNYRIGLFDLLDNE 181
PGN+EQV++L+ +++++I++ASLK+ +N + C IGV+F+D T Y++G+ D++DNE
Sbjct: 121 PGNIEQVNELMNMNIDSSIIIASLKVQWNSQDGN--CIIGVAFIDTTAYKVGMLDIVDNE 178
Query: 182 VFSNLESCLIQLGIKECLIPDLRDNPSMANDLKKILSVIDRCSCVASFVKPSDFNGKDVE 241
V+SNLES LIQLG+KECL+ DL N + +++K+++VIDRC CV + +K S+F+ KDVE
Sbjct: 179 VYSNLESFLIQLGVKECLVQDLTSNSNSNAEMQKVINVIDRCGCVVTLLKNSEFSEKDVE 238
Query: 242 ADLAKLCGDELSLSV-SKFSANCLGACSVLLNYLNIMNNEANVGNFEVVDHSLSQFVKLD 300
DL KL GD+L+LS+ K+S +GAC+ L+ YL +++ + VG +E+V+H L +F+KLD
Sbjct: 239 LDLTKLLGDDLALSLPQKYSKLSMGACNALIGYLQLLSEQDQVGKYELVEHKLKEFMKLD 298
Query: 301 ASAIKALNVFPTGSQGN--------TALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNEWL 352
ASAIKALN+FP G Q + S G+ K +SLFQLLN CKTN+GVRLLNEWL
Sbjct: 299 ASAIKALNLFPQGPQNPFGSNNLAVSGFTSAGNSGKVTSLFQLLNHCKTNAGVRLLNEWL 358
Query: 353 KQPLTDIDQITKRHDLVEFFMDQLELRSSLQEECLPSVPDIRRLTKKLQKNGNLEDVLKI 412
KQPLT+ID+I KRHDLV++ +DQ+ELR L E LP +PDIRRLTKKL K GNLEDVLKI
Sbjct: 359 KQPLTNIDEINKRHDLVDYLIDQIELRQMLTSEYLPMIPDIRRLTKKLNKRGNLEDVLKI 418
Query: 413 YQFAQMVPVISDLLKQKTEEVDSND-LMILVKEVLLDPMLENANPLEKLKELVETTVDLE 471
YQF++ +P I + E+ + + LV+ V L P+ + PL K +E+VETTVDL+
Sbjct: 419 YQFSKRIPEIVQVFTSFLEDDSPTEPVNELVRSVWLAPLSHHVEPLSKFEEMVETTVDLD 478
Query: 472 AYEETNEFMIKVEFNEQLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKLKLENHHLHG 531
AYEE NEFMIKVEFNE+L IR+ LD L+D I +IHLD+A+DLGFDP+KKLKLENHHLHG
Sbjct: 479 AYEENNEFMIKVEFNEELGKIRSKLDTLRDEIHSIHLDSAEDLGFDPDKKLKLENHHLHG 538
Query: 532 WCMRLTRNDAKALRQHKKYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQASLVKE 591
WCMRLTRNDAK LR+HKKYIELSTVKAGIFFSTK+LK+IA ET+ LQK+Y++QQ++LV+E
Sbjct: 539 WCMRLTRNDAKELRKHKKYIELSTVKAGIFFSTKQLKSIANETNILQKEYDKQQSALVRE 598
Query: 592 IVSITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTELIASR 651
I++ITL+YTPV EKLS+V A LD++ SFA SSYAPIPY+RPK++P+ D R T LI+SR
Sbjct: 599 IINITLTYTPVFEKLSLVLAHLDVIASFAHTSSYAPIPYIRPKLHPM-DSERRTHLISSR 657
Query: 652 HPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFVPCD 711
HP++EMQDD++FISNDV L G +F++ITGPNMGGKSTYIRQ+GVI LMAQIGCFVPC+
Sbjct: 658 HPVLEMQDDISFISNDVTLESGKGDFLIITGPNMGGKSTYIRQVGVISLMAQIGCFVPCE 717
Query: 712 EAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTYD 771
EA+IA VDAILCRVGAGDSQLKGVSTFM+E+LETASILKNA+ NSL+IVDELGRGTSTYD
Sbjct: 718 EAEIAIVDAILCRVGAGDSQLKGVSTFMVEILETASILKNASKNSLIIVDELGRGTSTYD 777
Query: 772 GFGLAWSISEHIATNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIEDN---GSHNSD 828
GFGLAW+I+EHIA+ I CF LFATHFHELT L++KL NV NMHVVAHIE N H+ +
Sbjct: 778 GFGLAWAIAEHIASKIGCFALFATHFHELTELSEKLPNVKNMHVVAHIEKNLKEQKHDDE 837
Query: 829 DITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRKAAELEDLKKDNDSLKKAKLSPE 888
DITLLYKVE G SDQSFGIHVAEVVQFP KIV MAKRKA EL+DLK +N+ LKKAKLS +
Sbjct: 838 DITLLYKVEPGISDQSFGIHVAEVVQFPEKIVKMAKRKANELDDLKTNNEDLKKAKLSLQ 897
Query: 889 DIVLGTESLKKSLKVWCKELKKNNLIDRLDDPS--VQEECVDKLKQQIDNLARE-EDTTS 945
++ G LK LK W +++K+ + L DPS +E K+++ + +A E E
Sbjct: 898 EVNEGNIRLKALLKEWIRKVKE----EGLHDPSKITEEASQHKIQELLRAIANEPEKEND 953
Query: 946 LFVDWVRDTLL 956
++ +++ LL
Sbjct: 954 NYLKYIKALLL 964
>Hs4557761 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 934
Score = 631 bits (1628), Expect = e-180
Identities = 361/886 (40%), Positives = 549/886 (61%), Gaps = 58/886 (6%)
Query: 13 AEERGFYKRFLQLPQRSQNTIRLVDKSDYYIVVGDDALFVADQVYHTSSVLKDCKIDPST 72
A E GF + F +P++ T+RL D+ D+Y G+DAL A +V+ T V+K + P+
Sbjct: 14 AAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIK--YMGPAG 71
Query: 73 LRQFDLQEPLKYVTMSIQIVGNLLKTSLLELGKKIEIY----------DRNWKLLKTASP 122
+ L+ V +S + +K LL ++E+Y + +W L ASP
Sbjct: 72 AKN------LQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLAYKASP 125
Query: 123 GNLEQVDDLIVGS--VETNIVLASLKLNFNGTAASNYCTIGVSFVDNTNYRIGLFDLLDN 180
GNL Q +D++ G+ + +I + +K++ A +GV +VD+ ++GL + DN
Sbjct: 126 GNLSQFEDILFGNNDMSASIGVVGVKMS----AVDGQRQVGVGYVDSIQRKLGLCEFPDN 181
Query: 181 EVFSNLESCLIQLGIKECLIPDLRDNPSMANDLKKILSVIDRCSCVASFVKPSDFNGKDV 240
+ FSNLE+ LIQ+G KEC++P A D+ K+ +I R + + K +DF+ KD+
Sbjct: 182 DQFSNLEALLIQIGPKECVLP----GGETAGDMGKLRQIIQRGGILITERKKADFSTKDI 237
Query: 241 EADLAKLC----GDELSLSVSKFSAN--CLGACSVLLNYLNIMNNEANVGNFEVVDHSLS 294
DL +L G++++ +V N + + S ++ +L ++++++N G FE+ S
Sbjct: 238 YQDLNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFS 297
Query: 295 QFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNEWLKQ 354
Q++KLD +A++ALN+F QG SV SL LLN+CKT G RL+N+W+KQ
Sbjct: 298 QYMKLDIAAVRALNLF----QG-----SVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQ 348
Query: 355 PLTDIDQITKRHDLVEFFMDQLELRSSLQEECLPSVPDIRRLTKKLQKNG-NLEDVLKIY 413
PL D ++I +R +LVE F++ ELR +LQE+ L PD+ RL KK Q+ NL+D ++Y
Sbjct: 349 PLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLY 408
Query: 414 QFAQMVPVISDLLKQKTEEVDSNDLMILVKEVLLDPMLENANPLEKLKELVETTVDLEAY 473
Q +P + L++ + L+ V + P+ + + K +E++ETT+D++
Sbjct: 409 QGINQLPNVIQALEKHEGKHQK-----LLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQV 463
Query: 474 EETNEFMIKVEFNEQLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKLKLENHHLHGWC 533
E +EF++K F+ LS +R +++L+ +++ + A DLG DP K++KL++ G+
Sbjct: 464 EN-HEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYY 522
Query: 534 MRLTRNDAKALRQHKKYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQASLVKEIV 593
R+T + K LR +K + + K G+ F+ +L ++ EE ++ + +YE+ Q ++VKEIV
Sbjct: 523 FRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIV 582
Query: 594 SITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTELIASRHP 653
+I+ Y ++ L+ V AQLD + SFA VS+ AP+PYVRP + Q R L ASRH
Sbjct: 583 NISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILE-KGQGRII-LKASRHA 640
Query: 654 IVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEA 713
VE+QD++ FI NDV + F +ITGPNMGGKSTYIRQ GVI LMAQIGCFVPC+ A
Sbjct: 641 CVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESA 700
Query: 714 KIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTYDGF 773
+++ VD IL RVGAGDSQLKGVSTFM EMLETASIL++AT +SL+I+DELGRGTSTYDGF
Sbjct: 701 EVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGF 760
Query: 774 GLAWSISEHIATNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIEDNGSHNSDDITLL 833
GLAW+ISE+IAT I F +FATHFHELT LA+++ V+N+HV A + + +T+L
Sbjct: 761 GLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTE------ETLTML 814
Query: 834 YKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRKAAELEDLKKDNDS 879
Y+V+ G DQSFGIHVAE+ FP ++ AK+KA ELE+ + +S
Sbjct: 815 YQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGES 860
>7298155 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 854
Score = 441 bits (1135), Expect = e-123
Identities = 300/907 (33%), Positives = 462/907 (50%), Gaps = 131/907 (14%)
Query: 11 DIAEERGFYKRFLQLPQRSQNTIRLVDKSDYYIVVG-DDALFVADQVYHTSSVLKDCKID 69
D R F K +L ++ T+R D +D Y V G DD VA VY +++ +
Sbjct: 17 DTNARRNFIKFHAKLGEKPATTVRFFDHTDRYTVHGSDDCELVAKIVYKSTAFI------ 70
Query: 70 PSTLRQFDLQEPLKYVTMSIQIVGNLLKTSLLELGKKIEIYDRN---WKLLKTASPGNLE 126
L D +E L++V+MS ++ LL ++E+Y +N W++ SPGNL
Sbjct: 71 -GALLPDDKKETLQFVSMSKGNFELAVRELLLVRNYRVEVYVKNSSDWEIEYRGSPGNLL 129
Query: 127 QVDDLIVGSVET----NIVLASLKLNFNGTAASNYCTIGVSFVDNTNYRIGLFDLLDNEV 182
Q +D++ + E +I+ +KL+ G +GV+ V+ + + L + LD++
Sbjct: 130 QFEDILFSNKEVLVGNSIISLLVKLDGGGQRR-----VGVASVEQNDCKFQLLEFLDDDF 184
Query: 183 FSNLESCLIQLGIKECLIPDLRDNPSMANDLKKILSVIDRCSCVASFVKPSDFNGKDVEA 242
F+ LE+ ++ LG KECL+P S+ + + +++DR + + K S N D+
Sbjct: 185 FTELEATVVLLGPKECLLP------SIEGEYSAVKTLLDRNGVMITMPKKSGDN--DLLQ 236
Query: 243 DLAKLCG------------DELSLSVSKFSANCLGACSVLLNYLNIMNNEANVGNFEVVD 290
DL +L EL L ++ A + YL+++N+ N+G++E+
Sbjct: 237 DLNRLLRFAKGQQEDATGLKELQLQLAS------NALKTAIKYLDLVNDAGNLGHYEIKQ 290
Query: 291 HSLSQFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNE 350
L++FV LD++A+ ALN+ P + + S+ +L+ C+T G RL+ +
Sbjct: 291 LDLNRFVHLDSAAVAALNIMPKPGTHPSM-----PSYRWQSVLGVLDHCRTPQGHRLMGQ 345
Query: 351 WLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQEECLPSVPDIRRLTKKLQKNGNLEDVL 410
W+KQPL + + RH++V +CL PD D L
Sbjct: 346 WVKQPLRSRNILNDRHNIV---------------QCLLESPDTMETLSL--------DYL 382
Query: 411 KIYQFAQMVPVISDLLKQKTEEVDSNDLMILVKEVLLDPMLENANPLEKLKELVETTVDL 470
K LKQ E+V + +E+ + LV+ + D
Sbjct: 383 K-------------RLKQMVEQV------------------VDFEAIERGEYLVKASFDS 411
Query: 471 EAYEETNEFMIKVEFNEQLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKLKLENHHLH 530
E ++ + EL + + + +L D + ++KLE+
Sbjct: 412 RLME-----------------LQQMMTELYSKMEELQFKCSQELNLDGKNQVKLESVAKL 454
Query: 531 GWCMRLTRNDAKALRQHKKYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQASLVK 590
G R+T D LR++K Y + +K G+ F++ +L+ A+E + + +YE+QQ S+V+
Sbjct: 455 GHHFRITVKDDSVLRKNKNYRIVDVIKGGVRFTSDKLEGYADEFASCRTRYEEQQLSIVE 514
Query: 591 EIVSITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTELIAS 650
EI+ + + Y L L+ AQLD L SFA + AP PYVRPKM L + R L
Sbjct: 515 EIIHVAVGYAAPLTLLNNELAQLDCLVSFAIAARSAPTPYVRPKM--LEEGARELVLEDV 572
Query: 651 RHPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFVPC 710
RHP +E+Q+ V FI+N V + + +ITGPNMGGKSTYIR +G LMA IG FVPC
Sbjct: 573 RHPCLELQEHVNFIANSVDFKKEECNMFIITGPNMGGKSTYIRSVGTAVLMAHIGAFVPC 632
Query: 711 DEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTY 770
A I+ VD+IL RVGA D+ +KG+STFM+EM+ET+ I++ AT SLVI+DELGRGTSTY
Sbjct: 633 SLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVIIDELGRGTSTY 692
Query: 771 DGFGLAWSISEHIATNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIEDNGSHNSDDI 830
+G G+AWSI+EH+A CFTLFATHFHE+T LA+ L V N H+ A + +DD
Sbjct: 693 EGCGIAWSIAEHLAKETKCFTLFATHFHEITKLAETLSTVKNCHMAAVAD------ADDF 746
Query: 831 TLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRKAAELEDLKKDNDSLKKAKLSPEDI 890
TLLY+V +G ++SFGI VA + FP +V A+ E ED D K+ K E I
Sbjct: 747 TLLYQVRSGVMEKSFGIQVARLANFPEHVVQNAQEVYNEFEDEHVDKQK-KEDKALLEKI 805
Query: 891 VLGTESL 897
+ + L
Sbjct: 806 QVAIQQL 812
>CE21000 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 849
Score = 371 bits (952), Expect = e-102
Identities = 257/880 (29%), Positives = 439/880 (49%), Gaps = 52/880 (5%)
Query: 25 LPQRSQNTIRLVDKSDYYIVVGDDALFVADQVYHTSSVLKDCKIDPSTLRQFDLQEPLKY 84
L +S NTI + + +Y+ V GDDA FVA ++ + +K + +Q +KY
Sbjct: 17 LKSKSPNTIAIFSRGEYFSVYGDDATFVATNIFKSDVCVKTFTLSTDNSQQ------MKY 70
Query: 85 VTMSIQIVGNLLKTSLLELGKKIEIYDRN---WKLLKTASPGNLEQVDDLIVGSVETNIV 141
++++ +++ +++ L +E+Y WK+ K SPGN + I S + I
Sbjct: 71 ISVNRGQYEKVVRETIVLLRCSVELYSSEQGEWKMTKRGSPGNTVDFEQEIGVSDQAPI- 129
Query: 142 LASLKLNFNGTAASNYCTIGVSFVDNTNYRIGLFDLLDNEVFSNLESCLIQLGIKECLIP 201
L + + N T+ D N RI + + +D FS E C+ L E +
Sbjct: 130 ---LAIYIHPGDDDNRVTLCAW--DAGNVRIVISEYIDTPSFSQTEQCIFGLCPTEYI-- 182
Query: 202 DLRDNPSMANDLKKILSVIDRCSCVASFVKPSDFNGKDVEADLAKLCGDELSLSVSKFSA 261
L + S+A KKI S+ R K +D+ + + K +
Sbjct: 183 -LVNEGSVAPKAKKIASMFTRMEVH----NKQQLKPKSQWSDVIESVHLDYKDEAEKQNE 237
Query: 262 NCLGACSVLLNYLNIMNNEANVGNFEVVDHSLSQFVKLDASAIKALNVFPTGSQGNTALL 321
N +L + N + + + + ++ + +D+ A++AL +F L
Sbjct: 238 NIKECLQIL--HSNAADEYSISEKYSIFNYGTHGNMLIDSCAVEALELFQ---------L 286
Query: 322 SVGSPQKCSSL--FQLLNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELR 379
+ +K ++L + +LN+CKT G +LL +WL +PL ID I +R D+VE + +R
Sbjct: 287 NYNYLEKSNNLTLYNVLNKCKTLPGEKLLRDWLSRPLCQIDHINERLDIVEALFENQTIR 346
Query: 380 SSLQEECLPSVPDIRRLTKKLQKNGNLEDVLKIYQFAQMVPVISDLLKQKTEEVDSNDLM 439
L++ L +PD +L ++L + L+D+ + YQ A ++ + L Q +E +
Sbjct: 347 QKLRDSILARMPDCSQLARRLMRKCTLQDLNRFYQAATLLETVEMQLIQLSE---AEQFA 403
Query: 440 ILVKEVLLDPMLENANPLEKLKELVETTVDLEAYEETNEFMIKVEFNEQLSIIRTHLDEL 499
+ +L + E +E+ + L + D + +E E ++V+F ++ I L+++
Sbjct: 404 PSINRLLKSEITEILKKVERFQVLCDEFFDFDYEKENKEIRVRVDFVPEIQEISEKLEQM 463
Query: 500 KDAIRTIHLDTADDLGFDPEKKLKLENHHLHGWCMRLTRNDAKALRQHKKYIELSTVKAG 559
+ + + D LKL+ + +G+ R+T + K++R+ +I +T +G
Sbjct: 464 ERVAEKLRKKYSAKFECD---NLKLDKNSQYGFYFRVTLKEEKSIRKKDVHILETTKGSG 520
Query: 560 IFFSTKELKNIAEETSELQKKYEQQQASLVKEIVSITLSYTPVLEKLSVVTAQLDILCSF 619
+ FS EL +I +E E KY + + ++ + + P++ ++ + A LD+ S
Sbjct: 521 VKFSVGELSDINDEFLEFHLKYTRAEEEVISMLCKKAEEFIPLIPAMAQLIATLDVFVSL 580
Query: 620 AQVSSYAPIPYVRPKMYPLNDQNRTTELIASRHPIVEMQDDVTFISNDVKLVQGDSEFIV 679
+ ++ + Y RP + PL ++ EL RHP++E + FI NDV L + I+
Sbjct: 581 STFAATSSGIYTRPNLLPLG--SKRLELKQCRHPVIEGNSEKPFIPNDVVLDK--CRLII 636
Query: 680 ITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFM 739
+TG NMGGKSTY+R + L+AQIG FVPC A I+ VD I RVGA D Q +G+STFM
Sbjct: 637 LTGANMGGKSTYLRSAALSILLAQIGSFVPCSSATISVVDGIFTRVGASDKQSQGISTFM 696
Query: 740 MEMLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIATNINCFTLFATHFHE 799
EML+ ++IL+ AT NS V++DELGRGTST+DGFG+A +I++ I I C ++FATHFHE
Sbjct: 697 AEMLDCSAILQRATKNSFVVIDELGRGTSTFDGFGIASAIAQDILNRIQCLSIFATHFHE 756
Query: 800 LTTLADKLDNVSNMHVVAHIEDNGSHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKI 859
+ LA++ V+ + + IE+N +I +LYKV G + SFG+ VA++V +
Sbjct: 757 MGKLAEQPGAVA-LQMGVQIENN------EIHMLYKVFEGVAQCSFGLQVAKMVGIDENV 809
Query: 860 VNMAKRKAAELEDLKKDNDSLKKAKLSPEDIVLGTESLKK 899
+N A + LE + KK L DI SL K
Sbjct: 810 INKAAQLLEGLEKKLVIDSKKKKELLESADIRQAILSLVK 849
>SPBC24C6.12c [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 434
Score = 349 bits (895), Expect = 1e-95
Identities = 184/355 (51%), Positives = 231/355 (64%), Gaps = 36/355 (10%)
Query: 550 YIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQASLVKEIVSITLSYTPVLEKLSVV 609
Y ELST K G++F+TK L ++ + QK Y Q L +E++ I +Y P LE + V
Sbjct: 8 YTELSTQKNGVYFTTKRLHSLNNSYMDHQKSYRYHQNGLAREVIKIAATYGPPLEAIGQV 67
Query: 610 TAQLDILCSFAQVSSYAPIPYVRPKMYP-------------------------LNDQNRT 644
A LD++ SFA S+ A IPYVRP + + RT
Sbjct: 68 IAHLDVILSFAHASTVAVIPYVRPNIVDSSIAQEKHGQSSNILDIVSLEDTPNFEEIRRT 127
Query: 645 TE--------LIASRHPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIG 696
E L +RHP +E QDDV FI NDV L G SE ++ITGPNMGGKSTYIRQ+G
Sbjct: 128 LENNHCARLYLKQARHPCLEAQDDVKFIPNDVNLEHGSSELLIITGPNMGGKSTYIRQVG 187
Query: 697 VICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNS 756
VI +MAQIGC VPC+ A + +DAIL RVGA DSQLKG+STFM EMLETA+IL+ AT S
Sbjct: 188 VITVMAQIGCPVPCEVADLDIIDAILARVGASDSQLKGISTFMAEMLETATILRAATPRS 247
Query: 757 LVIVDELGRGTSTYDGFGLAWSISEHIATNINCFTLFATHFHELTTLADKLDNVSNMHVV 816
L+I+DELGRGTST DGFGLAW+I+EHI T I CF LFATH+HE+T L++++ V N+HV
Sbjct: 248 LIIIDELGRGTSTTDGFGLAWAITEHIVTQIGCFCLFATHYHEMTKLSEEITTVKNLHVT 307
Query: 817 AHIEDNGSHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRKAAELE 871
A++ G S D+ LLY V G+SD+SFGIHVA++ FP KI+ MA KAAELE
Sbjct: 308 AYV---GDSESKDVALLYNVCEGASDRSFGIHVAKLAHFPPKIIEMASNKAAELE 359
>SPBC19G7.01c [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 582
Score = 315 bits (806), Expect = 3e-85
Identities = 197/609 (32%), Positives = 336/609 (54%), Gaps = 72/609 (11%)
Query: 1 MSSRPDLKFSDIAEERGFYKRFLQLPQRSQNTIRLVDKSDYYIVVGDDALFVADQVYHTS 60
MSSR ++ +E + + ++P + NT+R+ D+ ++Y+ +G+DA FVA YHT+
Sbjct: 1 MSSRNASIANERTDEARMFNFYEKMP-KDTNTVRVFDRGEFYVAIGEDASFVAQNAYHTT 59
Query: 61 SVLKDCKIDPSTLRQFDLQEPLKYVTMSIQIVGNLLKTSLLELGKKIEIYDRN-----WK 115
SVLK + ++ Y +S + + L L K++EI+ N ++
Sbjct: 60 SVLKHHNVSNTS-----------YCNLSPSLFIKFAEDVLSNLAKRVEIWGANSAKTGFE 108
Query: 116 LLKTASPGNLEQVDDLIVG------SVETNIVLASLKLNFNGTAASNYCTIGVSFVDNTN 169
LLK ASPGN++ ++DL+V + ++ ++S+ L + IGV+F+D
Sbjct: 109 LLKQASPGNMQMLEDLLVSENYQESTAISDSSVSSVLLAVTTRVKQDQRIIGVAFIDPIL 168
Query: 170 YRIGLFDLLDNEVFSNLESCLIQLGIKECLIPDLRDNPSMAN--------DLKKILSVID 221
++G+ + +D++ ++N E+ ++Q+G KEC+I + N ++ ++ ++I+
Sbjct: 169 KKLGVSEFVDSDAYTNFEALIVQVGAKECIISQSGHESTNGNSAVSINTAEINRLRNIIE 228
Query: 222 RCSCVASFVKPSDFNGKDVEADLAKLCGD--------ELSLSVSKFSANCLGACSVLLNY 273
C + + ++ S+F+ +DVE +L+K+ EL L ++ + +C+ LL Y
Sbjct: 229 GCGALVTTIRSSEFSARDVELELSKVLDSPVTHALVPELGLQLA------MASCNALLRY 282
Query: 274 LN--IMN------NEANVGNFEVVDHSLSQFVKLDASAIKALNVFPTGSQGNTALLSVGS 325
L ++N E + H+L Q+++LD +A+++LN+ P + G+
Sbjct: 283 LGPALLNPDMEDDRENTSRKLHLYHHNLEQYMRLDIAAVRSLNLLPPPN---------GN 333
Query: 326 PQKCSSLFQLLNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQEE 385
K SL+ LLN C+T G R L W+ QPL D I +RHDLV ++ E R L ++
Sbjct: 334 AHKTMSLYGLLNHCRTAMGARNLRRWIVQPLLDAKSIERRHDLVSALVEDAEARQLLLDD 393
Query: 386 --CLPSVPDIRRLTKKLQK-NGNLEDVLKIYQFAQMVPVISDLLKQKTEEVDSNDLMILV 442
L S+PDI +L ++L + + +LEDV++IYQ A+ +P I +L T E LV
Sbjct: 394 DHLLRSIPDIPKLCRRLTRGSASLEDVVRIYQMAKALPKIVTVLDSLTSEHKD-----LV 448
Query: 443 KEVLLDPMLENANPLEKLKELVETTVDLEAYEETNEFMIKVEFNEQLSIIRTHLDELKDA 502
+V + + + LEKL ELVETT+DLEA + +++++I+ EF+E+L +R LDEL+ +
Sbjct: 449 DKVYTNVLNNHCKNLEKLIELVETTIDLEALD-SHQYIIRAEFDEELLDLRQRLDELQHS 507
Query: 503 IRTIHLDTADDLGFDPEKKLKLENHHLHGWCMRLTRNDAKALR-QHKKYIELSTVKAGIF 561
I H DL D EKKL LE HHL+GWC+RLTR +A LR + Y ELST K G++
Sbjct: 508 IFEEHKRVGSDLHQDTEKKLHLEQHHLYGWCLRLTRTEAGCLRGRSSHYTELSTQKNGVY 567
Query: 562 FSTKELKNI 570
F+TK L ++
Sbjct: 568 FTTKRLHSL 576
>SPCC285.16c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1254
Score = 236 bits (603), Expect = 1e-61
Identities = 224/890 (25%), Positives = 400/890 (44%), Gaps = 93/890 (10%)
Query: 18 FYKRFLQLPQRSQNTIRLVDKSDYYIVVGDDALFVADQVYHTSSVLK-DCKIDPSTLRQF 76
F K+F ++ + +T+ K +Y + +DA + QV+ + + K+ F
Sbjct: 377 FEKQFWKIKKDLMDTVVFFQKGKFYELYENDAA-IGHQVFSLKLTDRVNMKMVGIPEASF 435
Query: 77 DLQEPLKYVTMSIQIVG-NLLKTSLLELGKKIEIYDRNWKLLKTASPGNLEQVDDLIVGS 135
D +++ +I + L+T+L GK+I+ R K K G L QV L G+
Sbjct: 436 DYWAS-QFIAKGYRIARVDQLETAL---GKEIKDRQRTQKEEKVVQRG-LTQV--LTSGT 488
Query: 136 VETNIVLAS------LKLNFNGTAASNYCTIGVSFVDNTNYRIGLFDLLDNEVFSNLESC 189
+ +L S + + + + + + G+ F+D + + + D+ + L++
Sbjct: 489 LVDEAMLTSDLSTYCMAIKESLQSDNEEPSFGICFIDTSTGGFHMCEFTDDIHRTKLDTL 548
Query: 190 LIQLGIKECLIPDLRDNPSMANDLKKILSVIDRCSCVASFVKPSD--FNGKDVEADLAKL 247
L Q+ KE ++ + + +K +S S + +F+KP ++ + VE ++ +
Sbjct: 549 LTQVRPKELILEKSKISQKSIRAIKYCVS----SSSIWNFIKPYTEFWDNERVEREI--I 602
Query: 248 CGDELS-------------LSVSKFSANCLGACSVLLNYLNIMNNEANVGNFEVVDHSL- 293
GD LS + + GA L L + + ++GNF+ D S
Sbjct: 603 AGDYFKNGLEGAPKILKSYLSEKPLAISAFGALFWYLRQLKLDKDMCSMGNFDEYDASQQ 662
Query: 294 SQFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNEWLK 353
S + ++ +K L +F G + +LF LL RC T G RL + WL
Sbjct: 663 STSLLMNGQTLKNLEIFSNSFDGGSE----------GTLFHLLCRCVTPFGKRLFHTWLC 712
Query: 354 QPLTDIDQITKRHDLVEFFMDQLELRSSLQEECLPSVPDIRRLTKKLQKNGNLE-DVLKI 412
PL I R D+VE D +R ++ L +PD+ RL ++ + D +++
Sbjct: 713 HPLRSGTAINARLDVVELIADNPVIRDTIWG-FLHKLPDLERLISRVHAGRSKPADFVRV 771
Query: 413 YQFAQMVPVISDLLKQKTEEVDSNDLMILVKEVLLDPMLENANPLEKLKELVETTVDLEA 472
+ Q + D L+++ EV + LL ++++A +++ E + +
Sbjct: 772 LEGFQRINSAFDQLREEFMEV--------AEGTLLGEIIQSAPNMKEELEAWTRAFNWQK 823
Query: 473 YEETNEFMIKVEFNEQLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKLKLENHHLHGW 532
E F ++ F + + + ELK+ + + LE +
Sbjct: 824 ASEEGVFEPEIGFEAEYDTSQKYQSELKNELYAL-----------------LEQYKKQLR 866
Query: 533 CMRLT-RNDAKALRQHK---------KYIELSTVKAGIFFSTKELKNIAEETSELQKKYE 582
C L +N K + Q + + ++S K + EL+ ++ E ++ +
Sbjct: 867 CSSLNFKNIGKEVYQVEVPSDVKVPVNWCKMSGTKKTNRYYNDELRKKIKKLLEAEELHL 926
Query: 583 QQQASLVKEI-VSITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQ 641
+ + ++ + +Y L + TA +D S +Q ++ PY RP++ D
Sbjct: 927 AIMSRMQEKFYIRFDSNYEQWLALIKY-TASIDCFFSLSQAAAALGEPYCRPEIIEQKDG 985
Query: 642 NRTTELIASRHPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLM 701
+ E + RHP + TF+ NDV L IV+TGPNM GKST +RQ+ + +M
Sbjct: 986 HLYFEEL--RHPCINASAASTFVPNDVVLGGESPNMIVLTGPNMAGKSTLLRQVCIAVIM 1043
Query: 702 AQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVD 761
AQ+GC+VP A I + +I R+GA D + STFM+E+ ET IL SLVI+D
Sbjct: 1044 AQLGCWVPAKRASITPMTSIYTRLGANDDIMSARSTFMVELSETKKILDECGPKSLVILD 1103
Query: 762 ELGRGTSTYDGFGLAWSISEHIATNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIED 821
ELGRGTSTYDG +A+++ H+ +NI C F+TH+ L V M + A +++
Sbjct: 1104 ELGRGTSTYDGHAIAYAVLHHLVSNIGCLGFFSTHYQSLCVDFMHHRQVRLMQMAAAVDE 1163
Query: 822 NGSHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRKAAELE 871
+T LYK+E G +S+G++VA + P K+++ A+ KA+ELE
Sbjct: 1164 KIRR----VTFLYKLEDGICPKSYGMNVASMAGLPEKVIDAAEEKASELE 1209
>ECU03g0540 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 730
Score = 234 bits (597), Expect = 5e-61
Identities = 173/528 (32%), Positives = 274/528 (51%), Gaps = 54/528 (10%)
Query: 339 CKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQEECLPSVPDIRRLTK 398
C TN G RLL+ L QPL + D+I +R D+V+ LR+ L L PD+ RL+K
Sbjct: 250 CYTNQGWRLLHRMLLQPLRNKDEIERRLDIVD------SLRT-LNLGILKRFPDLLRLSK 302
Query: 399 KLQKNG-NLEDVLKIYQFAQMVPVISDLLKQKTEEVD-SNDLMILVKEVLLDPMLENANP 456
++ +L ++L++ AQ V I +L+ + + S D+ +K++ L
Sbjct: 303 RVSSGRVSLREILRL---AQTVDTIPELMSSFSSSLALSKDVGETLKKIFL--------A 351
Query: 457 LEKLKELVETTVDLEAYEETNEFMIKVEFNEQLSIIRTHLDELKDAIRTIHLDTADDLGF 516
+ + +DLEA EE N + ++ + +E+L + L E+ ++ + G
Sbjct: 352 FVPFRNEITRVIDLEAAEE-NVYRVRPDVSERLQKLNRALAEVDGKMQKEYERVC---GI 407
Query: 517 DPEKKLKLENHHLHGWCMRLTRNDAKALRQHKKYIELSTVKAGIFFSTKELKNIAEETSE 576
P K+ + R+ + L + + ++ELS VK G+ F+T+ L + E
Sbjct: 408 YPRAKVDRNSGAFKTAKAEYQRS--QDLFKKEGFVELSFVKGGVSFTTRVLSLLNERRES 465
Query: 577 LQKKYEQQQASLVKEIVSITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMY 636
L+K+ + ++ ++ + + +YTP LE L+ +TA +D+ +F+ ++ Y RP +
Sbjct: 466 LKKEIDDEEKEIMDGVKTALKNYTPYLESLNHLTALVDVFSAFSIKATLKG--YSRPIV- 522
Query: 637 PLNDQNRTTELIASRHPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIG 696
E+ HP++E QD +I N +K+ D V+TGPNMGGKST+++ G
Sbjct: 523 ----GGTMLEIENGFHPVLEDQD---YIPNSIKME--DRRMCVVTGPNMGGKSTFLKTCG 573
Query: 697 VICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNS 756
VI L+A +GC+VP + A I +D I RVGAGD G STFMMEM + A I + ++ S
Sbjct: 574 VIALLAHMGCYVPAEYASIPILDGIYTRVGAGDCSFTGSSTFMMEMADIARICRLSSPES 633
Query: 757 LVIVDELGRGTSTYDGFGLAWSISEHIATNINCFTLFATHFHELTTLADKLDNVSNMHVV 816
L+I+DELGRGTS DG +A ++ EH+ L ATHF EL D+V N
Sbjct: 634 LIIIDELGRGTSAVDGLSIAQAVKEHLILK-KSLCLCATHFPELCG-----DDVLNKKA- 686
Query: 817 AHIEDNGSHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAK 864
SD L+Y+V G D SFGI VAE V FP++++ MAK
Sbjct: 687 ---------KSDGTLLMYEVVDGICDTSFGIMVAEKVGFPAEVIEMAK 725
>Hs20535615 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 936
Score = 214 bits (544), Expect = 7e-55
Identities = 197/747 (26%), Positives = 339/747 (45%), Gaps = 85/747 (11%)
Query: 160 IGVSFVDNTNYRIGLFDLLDNEVFSNLESCLIQLGIKECLIPDLRDNPSMANDLKKILSV 219
IG++ +D N +I L DN ++ + + L L E ++ + ++ N K +
Sbjct: 171 IGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTAC--AVGNSTKLFTLI 228
Query: 220 IDRCSCVA-SFVKPSDFNGKDVEADLAKLCGDELSLSVSKFSAN--CLGACSVLLNYLNI 276
+ V + ++ FN + +LC E S + + + CL A + LL Y+
Sbjct: 229 TENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAALLKYVEF 288
Query: 277 MNNEANVG-NFEVVDHSLSQFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQL 335
+ N + ++ Q +D+S+ + L + L++ + +LF +
Sbjct: 289 IQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLEL----------LINNQDYRNNHTLFGV 338
Query: 336 LNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQEECLPSVPDIRR 395
LN KT G R L + +PL DI+ I R D V+ + EL LQ
Sbjct: 339 LNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSV---------- 388
Query: 396 LTKKLQKNGNLEDVLKIYQFAQMVPVISDLLKQKTEEVDSNDL--MILVKEVL--LDPM- 450
+ + Q++ V+ + KQ T + + +I +K L +DP+
Sbjct: 389 -------------ISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLK 435
Query: 451 --LENAN-PLEK-------------LKELVETTVDLEAYEETNEFMIKVEFNEQLSIIRT 494
++N N PL + + E ++T ++ +A ++ + + +R+
Sbjct: 436 IAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQ---KCYAVRS 492
Query: 495 HLDELKDAIRTIHLDTADD-------LGFDPEKKLKLENHHLHGWCMRLTRNDAKALRQH 547
+++E D R + + DD LG L+ G+ +++T D AL
Sbjct: 493 NINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQMT-TDCIALPSD 551
Query: 548 K---KYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQASLVKEIVSITLSYTPVLE 604
+ ++I++S VK F++ +L + E E ++ +V +++S + L
Sbjct: 552 QLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLY 611
Query: 605 KLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTELIASRHPIVEMQDDVTFI 664
KLS + LD+L SFA + + YVRP+ T + HPI+E I
Sbjct: 612 KLSDTVSMLDMLLSFAHACTLSD--YVRPEF------TDTLAIKQGWHPILEKISAEKPI 663
Query: 665 SNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCR 724
+N+ + +G S F++ITGPNM GKSTY++QI + +MAQIG +VP + + I R
Sbjct: 664 ANNTYVTEG-SNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTR 722
Query: 725 VGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIA 784
+ D STFM EM E A IL NA SL+++DELGRGT+T +G G+ +++ E++
Sbjct: 723 ISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYL- 781
Query: 785 TNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIEDNGSHNSDDITLLYKVEAG-SSDQ 843
++ FTLFATHF EL + NV NMH N S N + I YK+ G + ++
Sbjct: 782 LSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEK 841
Query: 844 SFGIHVAEVVQFPSKIVNMAKRKAAEL 870
++G+ AEV P IV AK ++
Sbjct: 842 NYGLKAAEVSSLPPSIVLDAKEITTQI 868
>Hs4505251 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 936
Score = 213 bits (542), Expect = 1e-54
Identities = 196/747 (26%), Positives = 340/747 (45%), Gaps = 85/747 (11%)
Query: 160 IGVSFVDNTNYRIGLFDLLDNEVFSNLESCLIQLGIKECLIPDLRDNPSMANDLKKILSV 219
IG++ +D N +I L DN ++ + + L L E ++ + ++ N K +
Sbjct: 171 IGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTAC--AVGNSTKLFTLI 228
Query: 220 IDRCSCVA-SFVKPSDFNGKDVEADLAKLCGDELSLSVSKFSAN--CLGACSVLLNYLNI 276
+ V + ++ FN + +LC E S + + + CL A + LL Y+
Sbjct: 229 TENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAALLKYVEF 288
Query: 277 MNNEANVG-NFEVVDHSLSQFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQL 335
+ N + ++ Q +D+S+ + L + L++ + +LF +
Sbjct: 289 IQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLEL----------LINNQDYRNNHTLFGV 338
Query: 336 LNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQEECLPSVPDIRR 395
LN KT G R L + +PL DI+ I R D V+ + EL LQ
Sbjct: 339 LNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSV---------- 388
Query: 396 LTKKLQKNGNLEDVLKIYQFAQMVPVISDLLKQKTEEVDSNDL--MILVKEVL--LDPM- 450
+ + Q++ V+ + +Q T + + +I +K L +DP+
Sbjct: 389 -------------ISRFLDTEQLLSVLVQIPEQDTVNAAESKITNLIYLKHTLELVDPLK 435
Query: 451 --LENAN-PLEK-------------LKELVETTVDLEAYEETNEFMIKVEFNEQLSIIRT 494
++N N PL + + E ++T ++ +A ++ + + +R+
Sbjct: 436 IAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQ---KCYAVRS 492
Query: 495 HLDELKDAIRTIHLDTADD-------LGFDPEKKLKLENHHLHGWCMRLTRNDAKALRQH 547
+++E D R + + DD LG L+ + G+ +++T D AL
Sbjct: 493 NINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSLSSVRGFFIQMT-TDCIALPSD 551
Query: 548 K---KYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQASLVKEIVSITLSYTPVLE 604
+ ++I++S VK F++ +L + E E ++ +V +++S + L
Sbjct: 552 QLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLY 611
Query: 605 KLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTELIASRHPIVEMQDDVTFI 664
KLS + LD+L SFA + + YVRP+ T + HPI+E I
Sbjct: 612 KLSDTVSMLDMLLSFAHACTLSD--YVRPEF------TDTLAIKQGWHPILEKISAEKPI 663
Query: 665 SNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCR 724
+N+ + +G S F++ITGPNM GKSTY++QI + +MAQIG +VP + + I R
Sbjct: 664 ANNTYVTEG-SNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTR 722
Query: 725 VGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIA 784
+ D STFM EM E A IL NA SL+++DELGRGT+T +G G+ +++ E++
Sbjct: 723 ISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYL- 781
Query: 785 TNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIEDNGSHNSDDITLLYKVEAG-SSDQ 843
++ FTLFATHF EL + NV NMH N S N + I YK+ G + ++
Sbjct: 782 LSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEK 841
Query: 844 SFGIHVAEVVQFPSKIVNMAKRKAAEL 870
++G+ AEV P IV AK ++
Sbjct: 842 NYGLKAAEVSSLPPSIVLDAKEITTQI 868
>Hs4504191 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1360
Score = 213 bits (541), Expect = 1e-54
Identities = 201/741 (27%), Positives = 323/741 (43%), Gaps = 100/741 (13%)
Query: 232 PSDFNGKDVEADLAKLCGDELSLSVSKFSANCLGACSVLLNYLNIMNNEANVGNFE---- 287
P G E+D L E S + + + LG C L I ++ NFE
Sbjct: 656 PQVLKGMTSESDSIGLTPGEKS----ELALSALGGCVFYLKKCLIDQELLSMANFEEYIP 711
Query: 288 ------------VVDHSLSQFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQL 335
+ Q + LDA + L +F G+ G+T +L +
Sbjct: 712 LDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTE----------GTLLER 761
Query: 336 LNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQE--ECLPSVPDI 393
++ C T G RLL +WL PL + I R D +E D + + + E E L +PD+
Sbjct: 762 VDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIE---DLMVVPDKISEVVELLKKLPDL 818
Query: 394 RRLTKKLQ------KNGNLEDVLKI------YQFAQMVPVISDLLKQKT--------EEV 433
RL K+ K+ N D I Y +++ +S L K EEV
Sbjct: 819 ERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEV 878
Query: 434 DSNDLMILVKEVLLDPMLENANPLEKLKELV------ETTVDLEAYEETNEFMIKVEFNE 487
++K+V+ L+ NP + +L +T D E +T K F+
Sbjct: 879 ADGFKSKILKQVI---SLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDS 935
Query: 488 QLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKLKLENHHLHGWCMRLTRNDAK----- 542
+ A+ I + L + +++ ++ + W + R +
Sbjct: 936 ----------DYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENF 985
Query: 543 ALRQHKKYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQASLV----KEIVSITLS 598
R + EL + K G K I ++ + L E++ SL + + +
Sbjct: 986 TTRNLPEEYELKSTKKGC--KRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKN 1043
Query: 599 YTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTELIASRHPIVEMQ 658
Y + + A LD+L A S P RP + D EL SRHP +
Sbjct: 1044 YKDWQSAVECI-AVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKT 1102
Query: 659 ---DDVTFISNDVKL-------VQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFV 708
DD FI ND+ + G + +++TGPNMGGKST +RQ G++ +MAQ+GC+V
Sbjct: 1103 FFGDD--FIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYV 1160
Query: 709 PCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTS 768
P + ++ +D + R+GA D + G STF +E+ ETASIL +AT +SLV+VDELGRGT+
Sbjct: 1161 PAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTA 1220
Query: 769 TYDGFGLAWSISEHIATNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIEDNGSHNSD 828
T+DG +A ++ + +A I C TLF+TH+H L + V H+ +E+ S
Sbjct: 1221 TFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQ 1280
Query: 829 D-ITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRKAAELEDLKKDNDSLKKAKLSP 887
+ IT LYK G+ +S+G + A + P +++ RKA E E + + ++ L+
Sbjct: 1281 ETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLAS 1340
Query: 888 EDIVLGTESLKKSLKVWCKEL 908
E + E++ K L + KEL
Sbjct: 1341 ERSTVDAEAVHKLLTL-IKEL 1360
>SPAC8F11.03 [L] KOG0218 Mismatch repair MSH3
Length = 1004
Score = 212 bits (540), Expect = 2e-54
Identities = 159/571 (27%), Positives = 280/571 (48%), Gaps = 46/571 (8%)
Query: 331 SLFQLLNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQEECLPSV 390
SLF +L+R T G R+L WL++PL D + I +R D VE +L S+ Q
Sbjct: 426 SLFWVLDRTYTRFGQRMLQRWLQKPLVDKENIIERLDAVE----ELAFNSNSQ------- 474
Query: 391 PDIRRLTKKLQKNGNLEDVLKIYQFAQMVPV-ISDLLK--QKTEEVDSNDLMILVKEVLL 447
++ + K L + +LE L + + P + +LK K S + K LL
Sbjct: 475 --VQAIRKMLYRLPDLEKGLSRIYYQRCTPSEMFHVLKGFYKAASAFSKNSYSCFKSALL 532
Query: 448 DPMLENANPLEKL---------KELVETTVDLEAYEETNEFMIKVEFNEQLSIIRTHLDE 498
+++ + + ++ E ++ +++ + F + E N+ + + E
Sbjct: 533 RRLIQQLPSISSIIDHFLGMFDQKEAENNNKVDMFKDIDNFDLSEEPNDVDYELAQEIRE 592
Query: 499 LKDAIRTIHLDTADDLGFDPEKKLKLENHHLHGW-----CMRLTRNDAKALRQHKKYIEL 553
LK +I + + L + L+ N W C+ +++ K +I+L
Sbjct: 593 LKMSILMVRTEMDFHLQ-ELRDYLEYPNLEFSIWGNVKFCIEVSKGCKKI---PPDWIKL 648
Query: 554 STVKAGIFFSTKELKNIAEETSELQKKYEQQQASLVKEIVSITLSYTPVLEKLSVVTAQL 613
S+ ++ F T +++++ E S ++ + + +S + L ++ V L
Sbjct: 649 SSTRSLFRFHTPKIQSLLIELSSHEENLTISSEKIYRSFLSRISEHYNELRNVTTVLGTL 708
Query: 614 DILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTELIASRHPIVEMQDDVTFISNDVKLVQG 673
D L SFA++SS + Y RP+ ++ + SRHP++E+ D +F+ N + L
Sbjct: 709 DCLISFARISSQSG--YTRPEF-----SDKELLIHESRHPMIELLSDKSFVPNHIHLSSD 761
Query: 674 DSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLK 733
++ITGPNMGGKS++++Q+ + +MAQ GCFVP A + D+IL R+G+ D+
Sbjct: 762 GVRCLLITGPNMGGKSSFVKQLALSAIMAQSGCFVPAKSALLPIFDSILIRMGSSDNLSV 821
Query: 734 GVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIATNINCFTLF 793
+STFM+EMLET +L AT S+VI+DELGRGTST DG +++++ ++ I + LF
Sbjct: 822 NMSTFMVEMLETKEVLSKATEKSMVIIDELGRGTSTIDGEAISYAVLHYLNQYIKSYLLF 881
Query: 794 ATHFHELTTLADKLD---NVSNMHVVAHIEDNGSHNSDDITLLYKVEAGSSDQSFGIHVA 850
THF L L + + +M + ED + S I+ LYK+ G + +S+G++VA
Sbjct: 882 VTHFPSLGILERRFEGQLRCFHMGYLKSKEDFETSVSQSISFLYKLVPGVASKSYGLNVA 941
Query: 851 EVVQFPSKIVNMAKRKAAELEDLKKDNDSLK 881
+ P I++ A + E KK ++ K
Sbjct: 942 RMAGIPFSILSRATEISENYE--KKHRNARK 970
>YDR097c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1242
Score = 210 bits (535), Expect = 7e-54
Identities = 181/742 (24%), Positives = 329/742 (43%), Gaps = 73/742 (9%)
Query: 161 GVSFVDNTNYRIGLFDLLDNEVFSNLESCLIQLGIKECLIPDLRDNPS-MANDLKKILSV 219
G +F+D + + + D+ + L++ + Q+ E ++ R+N S +AN + K S
Sbjct: 468 GAAFIDTATGELQMLEFEDDSECTKLDTLMSQVRPMEVVME--RNNLSTLANKIVKFNSA 525
Query: 220 --------------IDRCSCVASFVKPSDFNGKDVEADLAKLCGDELSLSVSKFSANCLG 265
D A + F+ ++ ++ K D + K + G
Sbjct: 526 PNAIFNEVKAGEEFYDCDKTYAEIISSEYFSTEEDWPEVLKSYYD----TGKKVGFSAFG 581
Query: 266 ACSVLLNYLNIMNNEANVGNFEVVDHSLSQF-VKLDASAIKALNVFPTGSQGNTALLSVG 324
L +L + N ++ N + D SQ + LD ++ L +F G+
Sbjct: 582 GLLYYLKWLKLDKNLISMKNIKEYDFVKSQHSMVLDGITLQNLEIFSNSFDGSDK----- 636
Query: 325 SPQKCSSLFQLLNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQE 384
+LF+L NR T G R++ +WL PL + I R D V+ + + LR L E
Sbjct: 637 -----GTLFKLFNRAITPMGKRMMKKWLMHPLLRKNDIESRLDSVDSLLQDITLREQL-E 690
Query: 385 ECLPSVPDIRRLTKKLQKNG-NLEDVLKIYQFAQMVPVISDLLKQKTEEVDSNDLMILVK 443
+PD+ R+ ++ ++D K+ + + + D LK + D + +
Sbjct: 691 ITFSKLPDLERMLARIHSRTIKVKDFEKVITAFETIIELQDSLKNNDLKGDVSKYISSFP 750
Query: 444 EVLLDPMLENANPLEKLKELVETTVDLEAYEETNEFMIKVEFNEQLSIIRTHLDELKDAI 503
E L++ + N E+ K + E + + +EF++ + I+ DEL + +
Sbjct: 751 EGLVEAVKSWTNAFERQKAINENII-------VPQRGFDIEFDKSMDRIQELEDELMEIL 803
Query: 504 RTIHLDTADDLGFDPEKKLKLENHHLHG-----WCMRLTRNDAKALRQHKKYIELSTVKA 558
T K+ K N + + + + K + + +++++ K
Sbjct: 804 MTYR------------KQFKCSNIQYKDSGKEIYTIEIPISATKNVPSN--WVQMAANKT 849
Query: 559 GIFFSTKELKNIAEETSELQKKYEQQQASLVKEIVS-ITLSYTPVLEKLSVVTAQLDILC 617
+ + E++ +A +E ++ ++ + L + Y + + +D L
Sbjct: 850 YKRYYSDEVRALARSMAEAKEIHKTLEEDLKNRLCQKFDAHYNTIWMPTIQAISNIDCLL 909
Query: 618 SFAQVSSYAPIPYVRPKMYPLNDQNRTTELI------ASRHPIVEMQDDVT--FISNDVK 669
+ + S Y P RP + D T+L + RHP + FI ND++
Sbjct: 910 AITRTSEYLGAPSCRPTIVDEVDSKTNTQLNGFLKFKSLRHPCFNLGATTAKDFIPNDIE 969
Query: 670 LVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCRVGAGD 729
L + ++TG N GKST +R + +MAQ+GC+VPC+ A + +D I+ R+GA D
Sbjct: 970 LGKEQPRLGLLTGANAAGKSTILRMACIAVIMAQMGCYVPCESAVLTPIDRIMTRLGAND 1029
Query: 730 SQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIATNINC 789
+ ++G STF +E+ ET IL AT+ SL++VDELGRG S+ DGF +A S+ H+AT+I
Sbjct: 1030 NIMQGKSTFFVELAETKKILDMATNRSLLVVDELGRGGSSSDGFAIAESVLHHVATHIQS 1089
Query: 790 FTLFATHFHELTTLADKLDNVSNMHVVAHIEDNGSHNSDDITLLYKVEAGSSDQSFGIHV 849
FATH+ L + V + ++ + D + N +T LYK+ G S+ SFG+HV
Sbjct: 1090 LGFFATHYGTLASSFKHHPQVRPLK-MSILVDEATRN---VTFLYKMLEGQSEGSFGMHV 1145
Query: 850 AEVVQFPSKIVNMAKRKAAELE 871
A + +I++ A+ A LE
Sbjct: 1146 ASMCGISKEIIDNAQIAADNLE 1167
>YCR092c [L] KOG0218 Mismatch repair MSH3
Length = 1047
Score = 209 bits (531), Expect = 2e-53
Identities = 172/641 (26%), Positives = 308/641 (47%), Gaps = 81/641 (12%)
Query: 299 LDASAIKALNVFP-TGSQGNTALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNEWLKQPLT 357
LD +++++L++F G +G SLF LL+ +T+ G+R+L EW+ +PL
Sbjct: 449 LDPNSLQSLDIFTHDGGKG--------------SLFWLLDHTRTSFGLRMLREWILKPLV 494
Query: 358 DIDQITKRHDLVEFFMDQLELRSSLQE--ECLPSVPDIRRLTKKLQKNGNLEDVLKIYQF 415
D+ QI +R D +E ++ + + L PD+ R ++ ++Y +
Sbjct: 495 DVHQIEERLDAIECITSEINNSIFFESLNQMLNHTPDLLRTLNRIMYGTTSRK--EVYFY 552
Query: 416 AQMVPVISDLLKQK----TEEVDSNDLMILVKEVLLDPMLENANPLEKLKELVE--TTVD 469
+ + D K +E S+D I + LL + N L +L T ++
Sbjct: 553 LKQITSFVDHFKMHQSYLSEHFKSSDGRIGKQSPLLFRLFSELNELLSTTQLPHFLTMIN 612
Query: 470 LEAYEETN-----------------EFMIKVEFNEQL--SIIRTHLDELKDAIRTIHLDT 510
+ A E N E +IK++ + S ++ L E++ ++ +L+
Sbjct: 613 VSAVMEKNSDKQVMDFFNLNNYDCSEGIIKIQRESESVRSQLKEELAEIRKYLKRPYLNF 672
Query: 511 ADDLGFDPEKKLKLENHHLHGWCMRLTRNDAKALRQHKKYIELSTVKAGIFFSTKELKNI 570
D++ + E K + K L +I+++ K F+T + +
Sbjct: 673 RDEVDYLIEVK----------------NSQIKDLPDD--WIKVNNTKMVSRFTTPRTQKL 714
Query: 571 AEETSELQKKYEQQQASLVKEIVS-ITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIP 629
++ + ++ KE ++ IT YT L K+++ AQ D + S A S +
Sbjct: 715 TQKLEYYKDLLIRESELQYKEFLNKITAEYTE-LRKITLNLAQYDCILSLAATS--CNVN 771
Query: 630 YVRPKMYPLNDQNRTTELIA--SRHPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGG 687
YVRP N +IA +R+PI+E D V ++ ND+ + + + +ITGPNMGG
Sbjct: 772 YVRPTFV-----NGQQAIIAKNARNPIIESLD-VHYVPNDIMMSPENGKINIITGPNMGG 825
Query: 688 KSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETAS 747
KS+YIRQ+ ++ +MAQIG FVP +E +++ + +L R+GA D + G STF +EML+
Sbjct: 826 KSSYIRQVALLTIMAQIGSFVPAEEIRLSIFENVLTRIGAHDDIINGDSTFKVEMLDILH 885
Query: 748 ILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIATNINC-FTLFATHFHELTTLADK 806
ILKN SL+++DE+GRGT T+DG +++++ ++ + +C LF THF L +
Sbjct: 886 ILKNCNKRSLLLLDEVGRGTGTHDGIAISYALIKYFSELSDCPLILFTTHFPMLGEIKSP 945
Query: 807 LDNVSNMHVVAHIEDNGSHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRK 866
L + N H+ E + + LYK++ G + S+G++VA++ + I+N A
Sbjct: 946 L--IRNYHMDYVEEQKTGEDWMSVIFLYKLKKGLTYNSYGMNVAKLARLDKDIINRAFSI 1003
Query: 867 AAELEDLKKDNDSLK----KAKLSPEDIVLGTESLKKSLKV 903
+ EL + D+LK ++ D + T+ L K L +
Sbjct: 1004 SEELRKESINEDALKLFSSLKRILKSDNITATDKLAKLLSL 1044
>At3g18525 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 422
Score = 207 bits (527), Expect = 6e-53
Identities = 133/423 (31%), Positives = 233/423 (54%), Gaps = 45/423 (10%)
Query: 5 PDLKFSDIAEERGFYKRFLQLPQRSQNTIRLVDKSDYYIVVGDDALFVADQVYHTSSVLK 64
P+LK D + +GF + LP ++ +R D+ DYY G++++F+A YHT++ L+
Sbjct: 12 PELKL-DAKQAQGFLSFYKTLPNDTR-AVRFFDRKDYYTAHGENSVFIAKTYYHTTTALR 69
Query: 65 DCKIDPSTLRQFDLQEPLKYVTMSIQIVGNLLKTSLLELGKK-IEIYD---RNWKLLKTA 120
+ L V++S + + + LLE +E+Y+ NW+L+KT
Sbjct: 70 QLGSGSNALSS---------VSISRNMFETIARDLLLERNDHTVELYEGSGSNWRLVKTG 120
Query: 121 SPGNLEQVDDLIVGS--VETNIVLASLKLNFNGTAASNYCTIGVSFVDNTNYRIGLFDLL 178
SPGN+ +D++ + ++ V+ S+ +F+ C IG+++VD T +GL + L
Sbjct: 121 SPGNIGSFEDVLFANNEMQDTPVVVSIFPSFH----DGRCVIGMAYVDLTRRVLGLAEFL 176
Query: 179 DNEVFSNLESCLIQLGIKECLIPDLRDNPSMANDLKKILSVIDRCSCVASFVKPSDFNGK 238
D+ F+NLES LI LG KEC+ P +N+ K + ++RC+ + + K +F G+
Sbjct: 177 DDSRFTNLESSLIALGAKECIFP---AESGKSNECKSLYDSLERCAVMITERKKHEFKGR 233
Query: 239 DVEADLAKLCGDELS-----LSVSKFSANCLGACSVLLNYLNIMNNEANVGNFEVVDHSL 293
D+++DL +L + +S + LGA LL++ +++NE N GNF + + +
Sbjct: 234 DLDSDLKRLVKGNIEPVRDLVSGFDLATPALGA---LLSFSELLSNEDNYGNFTIRRYDI 290
Query: 294 SQFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQLLNR-CKTNSGVRLLNEWL 352
F++LD++A++ALNV + + N K SLF L+NR C G RLL+ WL
Sbjct: 291 GGFMRLDSAAMRALNVMESKTDAN----------KNFSLFGLMNRTCTAGMGKRLLHMWL 340
Query: 353 KQPLTDIDQITKRHDLVEFFMDQLELRSSLQEECLPSVPDIRRLTKKLQ-KNGNLEDVLK 411
KQPL D+++I R D+V+ F+++ LR L++ L + D+ RL + L+ + G L+ ++K
Sbjct: 341 KQPLVDLNEIKTRLDIVQCFVEEAGLRQDLRQH-LKRISDVERLLRSLERRRGGLQHIIK 399
Query: 412 IYQ 414
+YQ
Sbjct: 400 LYQ 402
>At4g02070 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1324
Score = 203 bits (516), Expect = 1e-51
Identities = 172/618 (27%), Positives = 293/618 (46%), Gaps = 51/618 (8%)
Query: 295 QFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNEWLKQ 354
Q + LDA+A++ L +F G + +L+ LN+C T SG RLL WL +
Sbjct: 694 QHMVLDAAALENLEIFENSRNGGYS----------GTLYAQLNQCITASGKRLLKTWLAR 743
Query: 355 PLTDIDQITKRHDLVEFFMDQ-----LELRSSLQEECLPSVPDIRRLTKKL----QKNGN 405
PL + + I +R D V + LE R SL +PD+ RL ++ + +G
Sbjct: 744 PLYNTELIKERQDAVAILRGENLPYSLEFRKSLSR-----LPDMERLIARMFSSIEASGR 798
Query: 406 LEDVLKIYQFA---QMVPVISDLLKQKTEEVDSNDLMILVKEVLLDPMLENANPLEKLKE 462
D + +Y+ Q+ IS L +T + L ++K +L P + L
Sbjct: 799 NGDKVVLYEDTAKKQVQEFISTLRGCETMAEACSSLRAILKHDTSRRLLHLLTPGQSLPN 858
Query: 463 LVETTVDLEAYEETNEFMIKVEFNEQLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKL 522
+ + ++ +++ +++ N I DE D T ++ +K L
Sbjct: 859 ISSS---IKYFKDAFDWV--EAHNSGRVIPHEGADEEYDCA----CKTVEEFESSLKKHL 909
Query: 523 KLENHHLHGWCMR-LTRNDAKALRQHKKYI--------ELSTVKAGIF-FSTKELKNIAE 572
K + L + +T + L + + + EL + K G+ + T +K + +
Sbjct: 910 KEQRKLLGDASINYVTVGKDEYLLEVPESLSGSVPHDYELCSSKKGVSRYWTPTIKKLLK 969
Query: 573 ETSELQKKYEQQQASLVKEIVSITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVR 632
E S+ + + E S+ + ++ + +L TA+LD+L S A S R
Sbjct: 970 ELSQAKSEKESALKSISQRLIGRFCEHQEKWRQLVSATAELDVLISLAFASDSYEGVRCR 1029
Query: 633 PKMY-PLNDQNRTTELIASRHPIV--EMQDDVTFISNDVKLVQGD-SEFIVITGPNMGGK 688
P + +D HP++ + +F+ N+VK+ + + FI++TGPNMGGK
Sbjct: 1030 PVISGSTSDGVPHLSATGLGHPVLRGDSLGRGSFVPNNVKIGGAEKASFILLTGPNMGGK 1089
Query: 689 STYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASI 748
ST +RQ+ + ++AQIG VP + +++ VD I R+GA D + G STF+ E+ ETA +
Sbjct: 1090 STLLRQVCLAVILAQIGADVPAETFEVSPVDKICVRMGAKDHIMAGQSTFLTELSETAVM 1149
Query: 749 LKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIATNINCFTLFATHFHELTTLADKLD 808
L +AT NSLV++DELGRGT+T DG +A S+ EH + C F+TH+H L+
Sbjct: 1150 LTSATRNSLVVLDELGRGTATSDGQAIAESVLEHFIEKVQCRGFFSTHYHRLSVDYQTNP 1209
Query: 809 NVSNMHVVAHIEDNGSHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRKAA 868
VS H+ I + G +++T LY++ G+ +S+G++VA + P ++ A K+
Sbjct: 1210 KVSLCHMACQIGE-GIGGVEEVTFLYRLTPGACPKSYGVNVARLAGLPDYVLQRAVIKSQ 1268
Query: 869 ELEDLKKDNDSLKKAKLS 886
E E L N KL+
Sbjct: 1269 EFEALYGKNHRKTDHKLA 1286
>Hs4505249 [L] KOG0218 Mismatch repair MSH3
Length = 1128
Score = 202 bits (514), Expect = 2e-51
Identities = 183/696 (26%), Positives = 314/696 (44%), Gaps = 80/696 (11%)
Query: 243 DLAKLCGDELSLSVSKFSANCLGACSVLLNYLNIMNNEANVG---NFEVVDHSLSQFVKL 299
D + G ++ + + + + ++ YL N E + NF+ + + +F+ +
Sbjct: 470 DTVDIKGSQIISGIVNLEKPVICSLAAIIKYLKEFNLEKMLSKPENFKQLSSKM-EFMTI 528
Query: 300 DASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNEWLKQPLTDI 359
+ + ++ L + Q T + + GS L +L+ KT+ G R L +W+ QPL +
Sbjct: 529 NGTTLRNLEIL----QNQTDMKTKGS------LLWVLDHTKTSFGRRKLKKWVTQPLLKL 578
Query: 360 DQITKRHDLVEFFMDQLELRSSLQEECLPSVPDIRRLTKKL--QKNGNLEDVLKIYQFAQ 417
+I R D V + E L +PDI R + +K E L +
Sbjct: 579 REINARLDAVSEVLHSESSVFGQIENHLRKLPDIERGLCSIYHKKCSTQEFFLIVKTLYH 638
Query: 418 MVPVISDLLKQKTEEVDSNDLMILVKEV--LLDPMLENANPLEKLKELVETTVD-LEAYE 474
+ ++ + S+ L ++ E+ LL P+ + L+ L E D E ++
Sbjct: 639 LKSEFQAIIPAVNSHIQSDLLRTVILEIPELLSPV---EHYLKILNEQAAKVGDKTELFK 695
Query: 475 ETNEFMI----KVEFNEQLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKLKLENHHLH 530
+ ++F + K E + IR HL E++ ++ G E ++++N +
Sbjct: 696 DLSDFPLIKKRKDEIQGVIDEIRMHLQEIRKILKNPSAQYVTVSG--QEFMIEIKNSAV- 752
Query: 531 GWCMRLTRNDAKALRQHKKYIELSTVKAGIFFSTKELKN-----IAEETSELQKKYEQQQ 585
I VK G STK + I E L + EQ
Sbjct: 753 ------------------SCIPTDWVKVG---STKAVSRFHSPFIVENYRHLNQLREQLV 791
Query: 586 ASLVKEIVSITLSYTPVLEKLSVVT---AQLDILCSFAQVSSYAPIPYVRPKMYPLNDQN 642
E + ++ L A +D + S A+V+ Y RP + +
Sbjct: 792 LDCSAEWLDFLEKFSEHYHSLCKAVHHLATVDCIFSLAKVAKQGD--YCRPTV----QEE 845
Query: 643 RTTELIASRHPIVE--MQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICL 700
R + RHP+++ + + ++ N+ L + ++ITGPNMGGKS+YI+Q+ +I +
Sbjct: 846 RKIVIKNGRHPVIDVLLGEQDQYVPNNTDLSEDSERVMIITGPNMGGKSSYIKQVALITI 905
Query: 701 MAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIV 760
MAQIG +VP +EA I VD I R+GA D+ KG STFM E+ +TA I++ AT SLVI+
Sbjct: 906 MAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGRSTFMEELTDTAEIIRKATSQSLVIL 965
Query: 761 DELGRGTSTYDGFGLAWSISEHIATNINCFTLFATHFHELTTLADKLDN-VSNMHVVAHI 819
DELGRGTST+DG +A++ E+ ++ TLF TH+ + L + V N H+ +
Sbjct: 966 DELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFVTHYPPVCELEKNYSHQVGNYHMGFLV 1025
Query: 820 EDNGS--------HNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRKAAELE 871
++ S D +T LY++ G + +S+G++VA++ P +I+ A K+ ELE
Sbjct: 1026 SEDESKLDPGAAEQVPDFVTFLYQITRGIAARSYGLNVAKLADVPGEILKKAAHKSKELE 1085
Query: 872 DLKKDNDSLKKAKLSPEDIVLGTESLKKSLKVWCKE 907
L N K+ K + L T + L+ W +E
Sbjct: 1086 GL--INTKRKRLKYFAK---LWTMHNAQDLQKWTEE 1116
>CE28985 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1186
Score = 199 bits (505), Expect = 2e-50
Identities = 200/828 (24%), Positives = 362/828 (43%), Gaps = 127/828 (15%)
Query: 119 TASPGNLEQVDDLIVGSVETNI------VLASLKLNFNGTAASNYCTIGVSFVDNTNYRI 172
T + G L+ VD +GS + + +LA + + T S+Y GV +D T I
Sbjct: 362 TRTYGVLDGVD---LGSASSTLDPTAKHLLAIKEFHNPETGKSSY---GVCMIDTTTAHI 415
Query: 173 GLFDLLDNEVFSNLESCLIQLGIKECLIPDLRDNPSMANDLKKILSVI------------ 220
+ D++ S L + L + + + ++ + S+++ K I++ I
Sbjct: 416 RIGQFEDDDYRSQLRTLLANVIVVQAIV----ERGSISSTTKSIINGILFSVPVEHLLPK 471
Query: 221 ---DRCSCVASFVKPSDFNGKDV------------EADLAKLCGDELSLSVSKFSA---- 261
V V D+ G D ++ + + L++S F A
Sbjct: 472 KQFMTAEDVVRIVSNEDYYGSDASEWPEVLKGMLEDSSILPKPSTDWQLALSAFGAIFWY 531
Query: 262 --------NCLGACSVLLNYLNIMNNEANVGNFEVVDHSLSQFVKLDASAIKALNVFPTG 313
+ L +V + N M N+ E +D + + LD +A++ LN+ P G
Sbjct: 532 LRDSLIDVDMLSMRNVTIYNSNSMENDQKK---EKIDWNGKNLI-LDGTALENLNIVPNG 587
Query: 314 SQGNTALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFM 373
+ +SL+ ++N+C T G RLL WL QP D ++ +R +++ +
Sbjct: 588 RDSHL-----------TSLYYVINKCSTPFGRRLLRSWLLQPTCDPKKLEQRQKAIKWLV 636
Query: 374 D-QLELRSSLQEECLPSVPDIRRLTKKLQKNGN-------------LEDVLKIYQ--FAQ 417
+ L +PD+ RL +K+ G D +K Q A+
Sbjct: 637 SPDASSFMTTATATLKKIPDLDRLLQKIHTIGLKYRSEKHPDSRAIFFDTIKTNQKKIAE 696
Query: 418 MVPVISDLLKQKTEEVDSNDLMILVKE----VLLDPMLENANPLEKLKELV---ETTVDL 470
++ I K + + + KE LLD +L N +E++ E + E D
Sbjct: 697 LLAAIDGF---KLCNKLRKEYIKVQKEGEGCELLDELLGNEQEMEEVDENIYFFEKMFDR 753
Query: 471 EAYEETNEFMIKV----EFNEQLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKLKLEN 526
+ + + E++E L+ ++ L+EL D ++ + + F K+K
Sbjct: 754 STAMKDGKIVPNAGCDEEYDEALNRVKEALNELNDYKDSVAKKYSCSIKFVDSGKVK--- 810
Query: 527 HHLHGWCMRLTRNDAKALRQHKKYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQA 586
+ + + N + K S K I +ST + + + ++K+ +
Sbjct: 811 -----YLLEMPENTKVSSSFELK----SRRKGFIRYSTPDSEQLVAALDAVEKEKSKLGD 861
Query: 587 SLVKEIVSITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTE 646
+ + P+ + + + D+L S A + +P P+ D N T
Sbjct: 862 DATRRVFEQFGHKNPIWLETVKLVSSFDVLTSLALFAKSSPFEMCMPEF----DFNATDP 917
Query: 647 -LIASR--HPIVEMQ--DDVT----FISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGV 697
LI + HP + +Q ++VT FI+N + ++ +++TGPNMGGKST +RQ V
Sbjct: 918 YLIVDKGVHPCLALQSRNEVTQTTSFIANSTTMGASEAAVMLLTGPNMGGKSTLMRQTAV 977
Query: 698 ICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSL 757
+ ++A IG VP ++ +D I R+GA D + G STF +E+ ET +LKNAT +SL
Sbjct: 978 LAILAHIGSMVPAFSMRLTPIDRIFTRIGANDRIMCGESTFFIELKETDIMLKNATKHSL 1037
Query: 758 VIVDELGRGTSTYDGFGLAWSISEHIATNINCFTLFATHFHELTTLADKLDNV--SNMHV 815
++VDELGRGTST+DG +A ++ + I+ ++ C T F+TH+H + NV ++M
Sbjct: 1038 LLVDELGRGTSTFDGTAIASAVLQKISDDLACRTFFSTHYHSICDSFTNHPNVRLAHMKC 1097
Query: 816 VAHIEDNGSHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMA 863
V E+N +D+T LY++E+G +S+G + A++ ++V A
Sbjct: 1098 VVDKENNEDPTMEDVTFLYELESGICPKSYGFYAAKLAGIDHQVVRNA 1145
>CE24714 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 842
Score = 179 bits (454), Expect = 2e-44
Identities = 169/749 (22%), Positives = 329/749 (43%), Gaps = 57/749 (7%)
Query: 160 IGVSFVDNTNYRIGLFDLLDNEVFSNLESCLIQLGIKECLIPDLRDNPSMANDLKKILSV 219
IG++ D I L + +D+ ++ L++ + + +I + + L + L
Sbjct: 68 IGIALHDTCFPEIHLCEFVDSREYTTLKTMINVHEAFDIVIQNGNEERGSTKLLGEALMT 127
Query: 220 IDRCSCVASFVKPSDFNGKDVEADLAKLCGDELSLSVSKFSANCL------GACSVLLNY 273
+ + S + FN + E L L E VS S CL GA +VLL Y
Sbjct: 128 AFPEASLQS-ISSKYFNSERGERQLQSLMNAE----VSTVSEGCLRRTLALGALAVLLKY 182
Query: 274 LNIMNNEA-NVGNFEVVDHSLSQFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSL 332
++ V + + + ++ +D + ++L + + + +L
Sbjct: 183 IHETRCVFFRVKSLRIKEMGVNDTCMIDFVSWESLEIVDADDASKARKFQMKQKR---TL 239
Query: 333 FQLLNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQEECLPSVPD 392
+LN T +G RLL + QP TD+ I R + +E + + +L+ L+ L +
Sbjct: 240 MSVLNHTVTTNGYRLLRSSVLQPSTDVYLIQSRQEAIEELIGKPQLKDKLRRT-LSRAHE 298
Query: 393 IRRLTKKL----------QKNGNLEDVLKIYQFAQMVPVISDLLKQKTEEVDSNDLMILV 442
+ R+ + + ++K+ +++ I LL + ++ SN ++I
Sbjct: 299 LDRVIAMCIQTSTSWTVRESEAKINQIIKLMHTLKVIQGIRTLLH--SAKMKSN-ILIEK 355
Query: 443 KEVLLDPMLENANPL--EKLKE-LVETTVDLEAYEETNEFMIKVEFNEQLSIIRTHLDEL 499
E L DP + + EK+ + L++ + + T + I+ QL + R +E+
Sbjct: 356 TEFLKDPRFDQIMNILVEKVDDSLLDGKKNSLHLQNTKCYAIRHFVAVQLDLARQTYEEI 415
Query: 500 KDAIRTIHLDTADDLG--FDPEKKLKLENHHLHGWCMRLTRNDAKALRQHKKYIELSTVK 557
IR + A ++ F ++L G+ A+++ + ++++ +
Sbjct: 416 ---IRNVEETGAREIAEYFHGNSSVRLSFSQSRGFHYTFVTRQAESVTIPRYFLDVFRNR 472
Query: 558 AGIFFSTKELKNIAEETSELQKKYEQQQASLVKEIVSITLSYTPVLEKLSVVTAQLDILC 617
+ F+++++ + ++ + +V +++ PVL + +D LC
Sbjct: 473 TTVTFNSRKVIAYNDRLEQVVAEMFLASDVIVCDMIEEMQPMIPVLYYAMDALSSIDFLC 532
Query: 618 SFAQVSSYAPIPYVRPKMYPLNDQNRTTELIASRHPIVEMQDDVTFISNDVKLVQGDSEF 677
A S +P P + + RHPI++ D I+ND L + D F
Sbjct: 533 GLATYSDLRDT--CKPTFGP------SFSISQGRHPILDWDDSEKTITNDTCLTR-DRRF 583
Query: 678 IVITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVST 737
+ITGPNM GKSTY++Q + +MAQIGCF+P + A + + I R+G D ++ S
Sbjct: 584 GIITGPNMAGKSTYLKQTAQLAIMAQIGCFIPANYASLPIFNRIFSRMGHNDELIRNKSA 643
Query: 738 FMMEMLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIATNINCFTLFATHF 797
F EM + A+I++ A NSLV++DEL R TST +G + ++I E + + +T ATHF
Sbjct: 644 FASEMSDAAAIVQYADKNSLVVLDELARSTSTEEGIAITYAICEKV-LKLQSYTFLATHF 702
Query: 798 HELTTLADKLDNVSNMHVVAHIEDNGSHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPS 857
++ LA+ + + N H + ++N + + Y+ +G + E+ P
Sbjct: 703 LDIAALANYSNAIDNYHFLPQTDENSTKKHKLLRGQYR------GPLYGFELVELSTIPD 756
Query: 858 KIVNMAKRKAAEL----EDLKKDNDSLKK 882
+++ A+ A EL ED ++D DS ++
Sbjct: 757 EVIEHAQSLATELRANVEDTERDYDSERR 785
>Hs21361940 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 851
Score = 178 bits (451), Expect = 4e-44
Identities = 157/639 (24%), Positives = 288/639 (44%), Gaps = 47/639 (7%)
Query: 293 LSQFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNEWL 352
L+ V +D L +F + S + ++ G + S LF +LNRC G +LL W
Sbjct: 233 LTHLVNIDQDTYSVLQIFKSESHPSVYKVASGLKEGLS-LFGILNRCHCKWGEKLLRLWF 291
Query: 353 KQPLTDIDQITKRHDLVEFFMDQLEL-RSSLQEECLPSVPDIRRLTKKLQ-KNGNLEDVL 410
+P D+ +++ R D+++FF+ L + + L + ++ + K+++ + + D
Sbjct: 292 TRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHRLLGHIKNVPLILKRMKLSHTKVSDWQ 351
Query: 411 KIYQFAQMVPVISDLLKQKTEEVDSNDLMILVKEVLLDPMLENANPLEKLKELVETTVDL 470
+Y+ + D + + + ++ D E ++ L + L+ VD
Sbjct: 352 VLYKTVYSALGLRDACRSLPQSI----------QLFRDIAQEFSDDLHHIASLIGKVVDF 401
Query: 471 EAYEETNEFMIKVEFNEQLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKLKLENHHLH 530
E N F + + ++ + L L + + ++L + L
Sbjct: 402 EGSLAENRFTVLPNIDPEIDEKKRRLMGLPSFLTEVARKELENLD-SRIPSCSVIYIPLI 460
Query: 531 GWCMRLTRNDAKALRQHKK-----YIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQ 585
G+ + + R + + ++ LS K + + + K + +L + Q+
Sbjct: 461 GFLLSIPRLPSMVEASDFEINGLDFMFLSEEK--LHYRSARTKELDALLGDLHCEIRDQE 518
Query: 586 ASLVKEIVSITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTT 645
L+ ++ L+ VL ++ + ++LD+L + A S+ Y RP+ P Q
Sbjct: 519 TLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALA--SAARDYGYSRPRYSP---QVLGV 573
Query: 646 ELIASRHPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIG 705
+ RHP++E+ TF+ N + VITGPN GKS Y++Q+G+I MA +G
Sbjct: 574 RIQNGRHPLMELCAR-TFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVG 632
Query: 706 CFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGR 765
FVP +EA+I AVDAI R+ + +S G+STFM+++ + A + NAT SLV++DE G+
Sbjct: 633 SFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATAQSLVLIDEFGK 692
Query: 766 GTSTYDGFGLAWSISEH-IATNINCFTLF-ATHFHELTTLADKLDNVSNMHVVAHIEDNG 823
GT+T DG L ++ H +A C T+F AT+F L +L + +V ++
Sbjct: 693 GTNTVDGLALLAAVLRHWLARGPTCPTVFVATNFLSLV----QLQLLPQGPLVQYLTMET 748
Query: 824 SHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRKAAELEDLKKDNDSLKKA 883
+ +D+ Y+V G + S H A P K+V K E+ DL + +K
Sbjct: 749 CEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVARGK----EVSDLIRSGKPIKPV 804
Query: 884 KLSPEDIVLGTESLKKSLKVWCKELKKNNLIDRLDDPSV 922
K + LKK+ C+ L + L+DP++
Sbjct: 805 K----------DLLKKNQMENCQTLVDKFMKLDLEDPNL 833
>YDL154w [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 901
Score = 176 bits (447), Expect = 1e-43
Identities = 204/859 (23%), Positives = 361/859 (41%), Gaps = 128/859 (14%)
Query: 69 DPSTLRQFDLQEPLKYVTMSIQIVGNLLKTSLLELGKK-IEIYDRNWKLLKTASPGNLEQ 127
D ST+ FD E + M I G L S+L+ K ++ +D+++ + KT + +
Sbjct: 46 DSSTIFSFDFDEE---IVMCIDFSGGKLGCSILDYHTKTLKAFDQDYVVNKTTISSH-DL 101
Query: 128 VDDLIVGSVETNIVLASLKLNFNGTAASNYCTIGVSFVDNTNYRIGLFDLLD---NEVFS 184
+DD + S + +++L L + N T C + D +FD + +E+
Sbjct: 102 IDDADMSSNDISLLLGLLIMEANPTV----CLVPARLED------WIFDYIKTKCDEINC 151
Query: 185 NLESCLIQLGIKECLIPDLR----DNPSMANDLKKILSVIDRCSCVASFVKPSDFNGKDV 240
LE I+ K L+ L+ DN ++ ND+
Sbjct: 152 RLELQPIKRFKKWDLLQSLQLRGHDNQTILNDI--------------------------- 184
Query: 241 EADLAKLCGDELSLSVSKFSANCLGACSVLLNYLNIMNNEANV-------GNFEVVDHSL 293
L + + +V+ + C+ A L N +N+ FE V H +
Sbjct: 185 ------LSNSKFTTTVTLGTVGCILANHEQLGEYNDSTASSNMVTGRLVQNAFEDVIHGI 238
Query: 294 SQF-----VKLDASAIKALNVFPTGSQ-GNTALLSVGSPQKCSSLFQLLNRCKTNSGVRL 347
+ LD + I AL++FPT + G+ ++ G S+F+L N+ ++ R+
Sbjct: 239 RYIDIRDRMVLDENTISALHIFPTAHKLGHDKMMRNGF----FSVFELFNQVSSDYARRI 294
Query: 348 LNEWLKQPLTDIDQITKRHDLVEFFMD-QLELRSSLQEECLPSVPDIRRLTKKLQKN-GN 405
L WL PLT+ +I R+ ++ +D Q + S + + PD +L+
Sbjct: 295 LKSWLINPLTNKKRIETRYSIIRTLLDKQNAIIFSDLSQSIKRCPDAFGFINQLRSGKST 354
Query: 406 LEDVLKIYQFAQMVPVISDLLKQKTEEVDSNDLMILVKEVLLDPMLENANPLEKLKELVE 465
L K+ F + I L+ D +++ +K + + + L++ VE
Sbjct: 355 LGTWSKVASFLEKGIAIFQLVSSLKLGSDEANILHDIKNKV------DISALKECLRKVE 408
Query: 466 TTVDLEAYEETNEFMIKVEFNEQLSIIRTHLDELKDAIRTIH-------LDTADDLGFDP 518
T +D + +T I + +L R + L+ + + L+T
Sbjct: 409 TVIDFDTSRDTKTLTINTGVDNRLDECRNIYNHLEGILLDVARETQIFLLNTMPQEDCKT 468
Query: 519 EKKLKLENHHLH----GWCMRLTRNDAKALR--QHKKYIELSTVKAGIFFSTKELKNIAE 572
K L+ + ++ G+ + ++ L + ++ E+ I+F + + E
Sbjct: 469 TKSLEKLVNAVYIPQLGYLVTISVLMEPLLDGIPNLQWEEIFRSSENIYFKNGRVLELDE 528
Query: 573 ETSELQKKYEQQQASLVKEIVSITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVR 632
++ + ++ + L L +++ ++L+IL SFAQVS A Y
Sbjct: 529 TYGDIYGAISDFEIEILFSLQEQILRRKTQLTAYNILLSELEILLSFAQVS--AERNYAE 586
Query: 633 PKMYPLNDQNRTTELIASRHPIVEMQDDVTFISNDVKL-----------VQGDSEFIVIT 681
P++ + E+I RH + E D +I N + Q IV+T
Sbjct: 587 PQLV---EDECILEIINGRHALYETFLD-NYIPNSTMIDGGLFSELSWCEQNKGRIIVVT 642
Query: 682 GPNMGGKSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMME 741
G N GKS Y+ Q G+I +AQIGCFVP + A+I D IL R+ ++ K S+F+++
Sbjct: 643 GANASGKSVYLTQNGLIVYLAQIGCFVPAERARIGIADKILTRIRTQETVYKTQSSFLLD 702
Query: 742 MLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIATNINCFTLFA-THFHEL 800
+ A L AT SL+++DE G+GT DG L SI +++ + C + A THFHEL
Sbjct: 703 SQQMAKSLSLATEKSLILIDEYGKGTDILDGPSLFGSIMLNMSKSEKCPRIIACTHFHEL 762
Query: 801 ---TTLADKLDNVS------------NMHVVAHIEDNGSHNSDDITLLYKVEAGSSDQSF 845
L + + + N+ AH+ ++ H S+ IT L+KV+ G S QSF
Sbjct: 763 FNENVLTENIKGIKHYCTDILISQKYNLLETAHVGED--HESEGITFLFKVKEGISKQSF 820
Query: 846 GIHVAEVVQFPSKIVNMAK 864
GI+ A+V IV A+
Sbjct: 821 GIYCAKVCGLSRDIVERAE 839
>Hs4505253 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 834
Score = 176 bits (445), Expect = 2e-43
Identities = 156/639 (24%), Positives = 287/639 (44%), Gaps = 47/639 (7%)
Query: 293 LSQFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNEWL 352
L+ V +D L +F + S + ++ G + S LF +LNRC G +LL W
Sbjct: 216 LTHLVNIDQDTYSVLQIFKSESHPSVYKVASGLKEGLS-LFGILNRCHCKWGEKLLRLWF 274
Query: 353 KQPLTDIDQITKRHDLVEFFMDQLEL-RSSLQEECLPSVPDIRRLTKKLQ-KNGNLEDVL 410
+P D+ +++ R D+++FF+ L + + L + ++ + K+++ + + D
Sbjct: 275 TRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHRLLGHIKNVPLILKRMKLSHTKVSDWQ 334
Query: 411 KIYQFAQMVPVISDLLKQKTEEVDSNDLMILVKEVLLDPMLENANPLEKLKELVETTVDL 470
+Y+ + D + + + ++ D E ++ L + L+ VD
Sbjct: 335 VLYKTVYSALGLRDACRSLPQSI----------QLFRDIAQEFSDDLHHIASLIGKVVDF 384
Query: 471 EAYEETNEFMIKVEFNEQLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKLKLENHHLH 530
E N F + + ++ + L L + + ++L + L
Sbjct: 385 EGSLAENRFTVLPNIDPEIDEKKRRLMGLPSFLTEVARKELENLD-SRIPSCSVIYIPLI 443
Query: 531 GWCMRLTRNDAKALRQHKK-----YIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQ 585
G+ + + R + + ++ LS K + + + K + +L + Q+
Sbjct: 444 GFLLSIPRLPSMVEASDFEINGLDFMFLSEEK--LHYRSARTKELDALLGDLHCEIRDQE 501
Query: 586 ASLVKEIVSITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTT 645
L+ ++ L+ VL ++ + ++LD+L + A S+ Y RP+ P Q
Sbjct: 502 TLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALA--SAARDYGYSRPRYSP---QVLGV 556
Query: 646 ELIASRHPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIG 705
+ RHP++E+ TF+ N + VITGPN GKS Y++Q+G+I MA +G
Sbjct: 557 RIQNGRHPLMELCAR-TFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVG 615
Query: 706 CFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGR 765
FVP +EA+I AVDAI R+ + +S G+STFM+++ + A + NAT SLV++DE G+
Sbjct: 616 SFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATAQSLVLIDEFGK 675
Query: 766 GTSTYDGFGLAWSISEH-IATNINCFTLF-ATHFHELTTLADKLDNVSNMHVVAHIEDNG 823
GT+T DG L ++ H +A C +F AT+F L +L + +V ++
Sbjct: 676 GTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLV----QLQLLPQGPLVQYLTMET 731
Query: 824 SHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKRKAAELEDLKKDNDSLKKA 883
+ +D+ Y+V G + S H A P K+V K E+ DL + +K
Sbjct: 732 CEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVARGK----EVSDLIRSGKPIKPV 787
Query: 884 KLSPEDIVLGTESLKKSLKVWCKELKKNNLIDRLDDPSV 922
K + LKK+ C+ L + L+DP++
Sbjct: 788 K----------DLLKKNQMENCQTLVDKFMKLDLEDPNL 816
>ECU10g0710 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 922
Score = 165 bits (418), Expect = 3e-40
Identities = 152/567 (26%), Positives = 255/567 (44%), Gaps = 98/567 (17%)
Query: 331 SLFQLLNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFF--MDQLELRSSLQ----- 383
+LF+ ++ C T G RLL W+ PL + I KR ++ F MD +L+ +L
Sbjct: 419 TLFKAVDFCSTPFGQRLLRRWMMAPLVRKEDIVKRQEMALVFKRMDSTKLKEALGRIGDG 478
Query: 384 EECL-------PSVPDIRRLTKKLQKNGNLEDVLKIYQFAQMVPVISDLLKQKTEEVDSN 436
E L P+ D+ + + L DVL + + + D++ +K E+
Sbjct: 479 ERLLVRLYNGNPTAKDLSKFIRCLGACKETFDVLGMELRTRRLEGARDIV-EKAEDYSCR 537
Query: 437 DLMILV--------KEVLLDPMLENANPL-EKLKELVETTVDLEAYEETNEFMIKVEFNE 487
+LV E + P EN + L + E + DL+AY E
Sbjct: 538 IEEVLVWHRKVYDVTEAGISPGEENEDELCHLMSEKGKIEGDLDAY-----------LQE 586
Query: 488 QLSIIRTHLDELKDAIRTI-HLDTADDLGFDPEKKLKLENHHLHGWCMRLTRNDAKALRQ 546
Q + + +D + + ++ ++G +
Sbjct: 587 QKTRLGCPSIRFRDVGKDVFQMEVPKEIGVPSD--------------------------- 619
Query: 547 HKKYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQASLVKEIVSITLSYTPVLEKL 606
Y +S+VK + +++L+ + E E +++ Q + SL++ + + L + ++
Sbjct: 620 ---YFIMSSVKGVNRYYSRDLRKLVERYMECEERIFQSKGSLLRRAIDVLLPHVIFFRQV 676
Query: 607 SVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRT-TELIASRHPIVEMQDDV--TF 663
AQ+D SFA S +NRT T + +++ M + F
Sbjct: 677 FCELAQIDCYLSFATFSQ----------------RNRTSTPVFSTKLCFSGMSSPIYPAF 720
Query: 664 ISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILC 723
+ ND G +V+TG NMGGKST +R I +++Q+G V C + D I
Sbjct: 721 VENDY---DGCRRILVLTGANMGGKSTLLRTICFNVILSQVGMDVCCKRMETPLFDRIFT 777
Query: 724 RVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHI 783
R+GA D KG STFM+E+ ET++IL+++T +SLVI+DELGRGTST DG +A ++ E++
Sbjct: 778 RIGARDDLAKGESTFMIELGETSNILRHSTRDSLVIMDELGRGTSTKDGGCIARAVLEYL 837
Query: 784 ATNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIEDNGSHNSDDITLLYKVEAGSSDQ 843
C LF+TH+H + +++ VSN ++ + I+ DI LYK+ AG S
Sbjct: 838 KKK-ECHVLFSTHYH---GIIGEVEGVSNGYMSSVIKGR------DIVFLYKLVAGVSGD 887
Query: 844 SFGIHVAEVVQFPSKIVNMAKRKAAEL 870
S G++VA + P IV A+ EL
Sbjct: 888 SHGLYVARMAGVPDAIVERAEGIRKEL 914
>At4g25540 [L] KOG0218 Mismatch repair MSH3
Length = 1076
Score = 157 bits (396), Expect = 1e-37
Identities = 94/265 (35%), Positives = 145/265 (54%), Gaps = 26/265 (9%)
Query: 611 AQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTELIASRHPIVEMQDDVTFISNDVKL 670
A LD L S + +S YVRP+ + + + + RHP++E F+ ND +
Sbjct: 762 AALDCLHSLSTLSRNKN--YVRPEFVD-DCEPVEINIQSGRHPVLETILQDNFVPNDT-I 817
Query: 671 VQGDSEFI-VITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCRVGAGD 729
+ + E+ +ITGPNMGGKS YIRQ+ +I +MAQ+G FVP AK+ +D + R+GA D
Sbjct: 818 LHAEGEYCQIITGPNMGGKSCYIRQVALISIMAQVGSFVPASFAKLHVLDGVFTRMGASD 877
Query: 730 SQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIATNINC 789
S G STF+ E+ +ELGRGTST+DG +A++ +H+ C
Sbjct: 878 SIQHGRSTFLEEL------------------NELGRGTSTHDGVAIAYATLQHLLAEKRC 919
Query: 790 FTLFATHFHELTTLADKLDNVSNMHVVAHI---EDNGSHNSDDITLLYKVEAGSSDQSFG 846
LF TH+ E+ +++ + V+++ +D GS++ DD+T LYK+ G +SFG
Sbjct: 920 LVLFVTHYPEIAEISNGFPGSVGTYHVSYLTLQKDKGSYDHDDVTYLYKLVRGLCSRSFG 979
Query: 847 IHVAEVVQFPSKIVNMAKRKAAELE 871
VA++ Q P + A AA+LE
Sbjct: 980 FKVAQLAQIPPSCIRRAISMAAKLE 1004
>At4g17380 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 574
Score = 154 bits (390), Expect = 5e-37
Identities = 89/229 (38%), Positives = 133/229 (57%), Gaps = 15/229 (6%)
Query: 602 VLEKLSVVTAQLDILC-------SFAQVSSYAPIP-YVRPKMYPLNDQNRTTELIASRHP 653
+ E +S +T ++LC SFA S P+ Y RP++ + + A RHP
Sbjct: 307 IREDISALTLLAEVLCLLDMIVNSFAHTISTKPVDRYSRPEL----TDSGPLAIDAGRHP 362
Query: 654 IVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEA 713
I+E + F+SN + + + + +V+ GPNM GKSTY++Q+ ++ ++AQIGC+VP A
Sbjct: 363 ILESIHN-DFVSNSIFMSEA-TNMLVVMGPNMSGKSTYLQQVCLVVILAQIGCYVPARFA 420
Query: 714 KIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTYDGF 773
I VD I R+G D+ STFM EM ETA I++N T+ SL+++DELGR TS+ DG
Sbjct: 421 TIRVVDRIFTRMGTMDNLESNSSTFMTEMRETAFIMQNVTNRSLIVMDELGRATSSSDGL 480
Query: 774 GLAWSISEHIATNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIEDN 822
+AWS E++ ++ +T+FATH L LA NV +H I DN
Sbjct: 481 AMAWSCCEYL-LSLKAYTVFATHMDSLAELATIYPNVKVLHFYVDIRDN 528
>CE26678 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 1369
Score = 149 bits (375), Expect = 3e-35
Identities = 141/619 (22%), Positives = 261/619 (41%), Gaps = 48/619 (7%)
Query: 292 SLSQFVKLDASAIKALNVFPTGSQGNTALLSVGSPQKCSSLFQLLNRCKTNSGVRLLNEW 351
+L V++D + I+AL++ P ++ N G SL+QL+++C++ G + L +W
Sbjct: 273 TLGNLVEIDFNTIQALDILPKETE-NKKTFGQGR-----SLYQLMDKCRSTVGKKCLRKW 326
Query: 352 LKQPLTDIDQITKRHDLVEFFMDQLELRSSLQ-EECLPSVPDIRRLTKKLQKNGNLEDVL 410
+ P TD D + R V +F + + L V + + +K Q ++
Sbjct: 327 FRNPTTDRDDLVSRQKCVHYFKQDWNAEVTAKLSSILGRVKALNSVFQKFQSG--TAQLI 384
Query: 411 KIYQFAQMVPVISDLLKQKTEEVDSNDLMI---LVKEVLLDPMLENANPLEKLKELVETT 467
F V + ++L + S + + L++EV ++ + +
Sbjct: 385 HWECFVSTVNALVEILNIIRQTPISKEFPVESDLLREV------------SEIAVIAGSI 432
Query: 468 VDLEAYEETNEFMIKVEFNEQLSIIRTHLDELKDAIRTIHLDTADDLGFDPEKKLKLENH 527
++ + + +E+L IR + + + I LG P +
Sbjct: 433 INFAESKIQGRVTVMNGIDEELDEIRDTYENMPMVLTAIAKQEEARLGLPPYSNVACVYI 492
Query: 528 HLHGWCMRLTRNDAKALRQHKKYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQAS 587
L G+ + + R+ + L + + + +E ++ + Q +
Sbjct: 493 PLVGFVLSVPRD--YGVESQPDMTLLYSTHEDLRVRNATTSRLDDEFGDILMRLIDSQTA 550
Query: 588 LVKEIVSITLSYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTEL 647
++ + + + + KL + +++D+L SF +++ P E
Sbjct: 551 IILTLKTRVMKKKRSIIKLLSIASRIDVLISFGLIAAQ------NGWNCPALVDEPVIEA 604
Query: 648 IASRHPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCF 707
+ HPI + +F+ N V + + +ITGPN GKS Y++ IG++ ++ IG F
Sbjct: 605 VELYHPISVLVVKKSFVPNQVSSGRDGIKASIITGPNACGKSVYMKSIGIMVFLSHIGSF 664
Query: 708 VPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGT 767
VP AKI VD I+ R+ DS L G+STF ++ + A L+ AT NSLVI+DE G+GT
Sbjct: 665 VPARHAKIGIVDRIVTRMFTVDSVLDGMSTFAKDVEQVALALRKATGNSLVIIDEFGKGT 724
Query: 768 STYDGFGLAWSISEHIATN--INCFTLF-ATHFHELTTLADKLDNVSNMHVVAHIEDNGS 824
T G L S+ + C +F ++HFH L N++ + + G
Sbjct: 725 MTEVGLSLLASVMTYWMNRGADRCPHIFLSSHFHALPNYIPLETNIATFLTFTVLREAGG 784
Query: 825 HNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMAKR--KAAELEDLKKD------ 876
I L+++ G D SF + VA+ P ++ A R KA + L K+
Sbjct: 785 ----KIKYLFRMTPGLVDCSFALSVAKEEGIPPPVIGRACRIYKALKAGTLLKEIKAEVS 840
Query: 877 NDSLKKAKLSPEDIVLGTE 895
ND+ +K + D+VL E
Sbjct: 841 NDN-EKQLVEDMDVVLADE 858
>YFL003c [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 878
Score = 145 bits (365), Expect = 4e-34
Identities = 180/780 (23%), Positives = 333/780 (42%), Gaps = 123/780 (15%)
Query: 160 IGVSFVDNTNYRIGLFDLLDNEVFSNLESCLIQLGIKECLIPDLRDNPSMANDLKKILSV 219
IG+ ++ ++ L D +D++++ + L E LIP + S+A + K+ ++
Sbjct: 120 IGLCIINCNTGQMYLSDFMDSQIYIRVVHKLQIYQPTEILIP----SSSLAPTVSKLATM 175
Query: 220 IDRCSCVASFVKPSD-----FNGKDVEADLAKLCGDELSLS------VSKFSANCLGACS 268
I VA VK + FN +D A + K D+ + K A C A S
Sbjct: 176 IK--FNVAETVKIEEGSRKCFNSQDGLAAITKYLMDDTKKDLKIEEIIDKTFALC--AAS 231
Query: 269 VLLNYLN--IMNNEANVGNFE---VVDHSLSQFVKLDASAIKALNVFPTGSQGNTALLSV 323
++Y+ I + N+ F + + +D+ ++ L + N
Sbjct: 232 AAISYMEEIISKSSRNLNAFRKLRIQFEGTENTMLIDSKTVRGLELVENKLDKNGI---- 287
Query: 324 GSPQKCSSLFQLLNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQ 383
SL++ L+ T G R L + QPLTD I R + +E +L L+
Sbjct: 288 -------SLWKFLDTTSTKMGQRSLRNSILQPLTDRGSIEMRLEALEELKANDDLLQKLR 340
Query: 384 EECLPSVPDIRRLTKKL--------QKNGNLEDVLKIYQFAQMVPVISDLLKQKTEEVDS 435
E + S+PD+ +L +L + + + VL + + Q V + D L
Sbjct: 341 LE-MKSLPDLDKLFSRLLCINHSAIKPDQRINYVLLLKETLQSVKSLKDAL--------- 390
Query: 436 NDLMILVKEVLLDPMLENANPLEKLKELVETTVDLEAYEETNEFMIKVEFNEQLSIIRTH 495
ND +I + + + N + + ++++L+ + ++ + ++ + N++ +++
Sbjct: 391 NDQLIQSRLISETKKIFNNDAIMEIEKLINSCINEDCVWASSAIQL---LNQRSYAVKSD 447
Query: 496 LDELKDAIRTIHLDTADDLGFDPE-----KKLKLENHH--LHGWCMRLTR----NDAKAL 544
+ L D R I+ + ++ + E K+ L++++ G+ +R+ R +D L
Sbjct: 448 SNGLLDVSRQIYKEVKEEFFREVEDLTAKNKINLDHNYDSARGFYLRIKRQEFTDDVATL 507
Query: 545 RQ-------HKKYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQASLVKEIVSITL 597
K YIE +T+ I LK + EE L ++ V E++
Sbjct: 508 PDVFISRTIKKNYIECTTLN--IIKKNARLKEVMEEILLLSEE-------TVDELLDKIA 558
Query: 598 SYTPVLEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTELIA-------S 650
++ L ++ A LD++CSF Y L + N T + S
Sbjct: 559 THISELFMIAEAVAILDLVCSFT---------------YNLKENNYTIPIFTNNLLIRDS 603
Query: 651 RHPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQIGCFVPC 710
RHP++E F+ N + + S +ITG NM GKS Y++Q+ +IC+MAQ+G +P
Sbjct: 604 RHPLLEKVLK-NFVPNTISSTKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPA 662
Query: 711 DEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTY 770
+ RV DS S F EM E A L + +L+I+DELGRG+S
Sbjct: 663 LYGSFPVFKRLHARV-CNDSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIA 721
Query: 771 DGFGLAWSISEHIATNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIEDNGSHNSDDI 830
DGF ++ +++EH+ +THF ++ + K VS++H+ A + N + +
Sbjct: 722 DGFCVSLAVTEHL-LRTEATVFLSTHFQDIPKIMSKKPAVSHLHMDAVL-----LNDNSV 775
Query: 831 TLLYKVEAGS-SDQSFGIHVAEVVQFPSKIVNMAKRKAAELEDLKKDNDSLKKAKLSPED 889
+ Y++ S + ++ GI V + + P I +A + L K + KA+ ED
Sbjct: 776 KMNYQLTQKSVAIENSGIRVVKKIFNPDIIA-----EAYNIHSLLK----IAKARTENED 826
>At3g20475 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 321
Score = 108 bits (271), Expect = 3e-23
Identities = 85/268 (31%), Positives = 129/268 (47%), Gaps = 20/268 (7%)
Query: 630 YVRPKMYPLNDQNRTTELIASRHPIVEMQDDVTFISNDVKLVQGDSEFIVITGPNMGGKS 689
YVRP + ++ RH + EM D TFI ND + + + +ITGPN GKS
Sbjct: 36 YVRPVL----TVESLLDIRNGRHVLQEMAVD-TFIPNDTE-INDNGRIHIITGPNYSGKS 89
Query: 690 TYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTFMMEMLETASIL 749
Y++Q+ +I ++ IG FVP D A + D I C +G+ STFM+++ + +L
Sbjct: 90 IYVKQVALIVFLSHIGSFVPADAATVGLTDRIFCAMGS-KFMTAEQSTFMIDLHQVGMML 148
Query: 750 KNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIATNIN-CFTLFATHFHELTT-----L 803
+ AT SL ++DE G+GT T DG GL H AT + TH EL +
Sbjct: 149 RQATSRSLCLLDEFGKGTLTEDGIGLLGGTISHFATCAEPPRVVVCTHLTELLNESCLPV 208
Query: 804 ADKLDNVSNMHVVAHIEDNGSHNSDDITLLYKVEAGSSDQSFGIHVAEVVQFPSKIVNMA 863
++K+ M V+ D S N ++I LY+ G S S + ++ P +
Sbjct: 209 SEKI-KFYTMSVLR--PDTESANMEEIVFLYRY--GVSLTSILPKLPTFLRLPCVPEEVV 263
Query: 864 KRKAAELEDLKKDN--DSLKKAKLSPED 889
KR A L+ + +N D L K+S +D
Sbjct: 264 KRAAIVLDAFESNNNVDKLSLDKISSQD 291
>At3g24320 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1022
Score = 91.3 bits (225), Expect = 7e-18
Identities = 59/187 (31%), Positives = 96/187 (50%), Gaps = 9/187 (4%)
Query: 679 VITGPNMGGKSTYIRQIGVICLMAQIGCFVPCDEAKIAAVDAILCRVGAGDSQLKGVSTF 738
++TGPN GGKS+ +R I L+ G VP + A I D+I+ + + DS + G S+F
Sbjct: 669 LLTGPNGGGKSSLLRSICAAALLGISGLMVPAESACIPHFDSIMLHMKSYDSPVDGKSSF 728
Query: 739 MMEMLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIATNINCFTLFATHFH 798
+EM E SI+ AT SLV++DE+ RGT T G +A S+ E + T+ C + +TH H
Sbjct: 729 QVEMSEIRSIVSQATSRSLVLIDEICRGTETAKGTCIAGSVVESLDTS-GCLGIVSTHLH 787
Query: 799 ELTTLADKLDNVSNMHVVAHIEDNGSHNSDDITL-LYKVEAGSSDQSFGIHVAEVVQFPS 857
+ +L N++ + G+ N + T +K+ G +S A+ P
Sbjct: 788 GIFSLPLTAKNIT-------YKAMGAENVEGQTKPTWKLTDGVCRESLAFETAKREGVPE 840
Query: 858 KIVNMAK 864
++ A+
Sbjct: 841 SVIQRAE 847
>CE04858 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 107
Score = 72.4 bits (176), Expect = 3e-12
Identities = 35/100 (35%), Positives = 60/100 (60%), Gaps = 1/100 (1%)
Query: 725 VGAGDSQLKGVSTFMMEMLETASILKNATHNSLVIVDELGRGTSTYDGFGLAWSISEHIA 784
+G D ++ S F EM + A+I++ A NSLV++DEL R TST +G + ++I E +
Sbjct: 1 MGHNDELIRNKSAFASEMSDAAAIVQYADKNSLVVLDELARSTSTEEGIAITYAICEKV- 59
Query: 785 TNINCFTLFATHFHELTTLADKLDNVSNMHVVAHIEDNGS 824
++ +T ATHF ++ LA+ + + N H + I+DN +
Sbjct: 60 LKLHSYTFLATHFLDIAALANYSNAIDNYHFLPQIDDNST 99
>7294307 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 985
Score = 68.6 bits (166), Expect = 5e-11
Identities = 87/403 (21%), Positives = 162/403 (39%), Gaps = 48/403 (11%)
Query: 331 SLFQLLNRCKTNSGVRLLNEWLKQPLTDIDQITKRHDLVEFFMDQLELRSSLQE--ECLP 388
SL L+ C T G RLL+ WL P D+ I +R D + + + + + LQE L
Sbjct: 597 SLLSTLDHCCTKFGKRLLHHWLCAPSCDVSVIKERQDAIG---ELIRMPTELQEVRALLA 653
Query: 389 SVPDIRRLTKKLQKNGN-------------------LEDVLKIYQFAQMVPVISDLLKQK 429
+PD R ++ GN L + K+ F ++ +DL K
Sbjct: 654 PMPDFERNLAQIHLFGNKQIKQMDHPDSRAILFEEKLYNKQKLQGFMAVLKGFNDLTKLP 713
Query: 430 TEEVDSNDLMILVKEVLLDPMLENANP-LEKLKELVETTVDLEAYEETNEFMIKVEFNEQ 488
T + L+K + P + P L K + T D +A +T + + +
Sbjct: 714 T--MFHQCKTTLLKRITQLPESGGSFPDLSKELQYFATAFDHDAAAKTGVIAPQAGMDAE 771
Query: 489 LSIIRTHLDELKDAIRTIHLDTADDLGF------DPEKKLKLENHHLHGWCMRLTRNDAK 542
+ E++ ++T ++ G +K+ +L+ H +K
Sbjct: 772 YDAAMDSIGEVEKRLKTYLVEQERHFGCRITYFGSDKKRYQLDVPESHA---------SK 822
Query: 543 ALRQHKKYIELSTVKAGIFFSTKELKNIAEETSELQKKYEQQQASLVKEIVSITLSYTPV 602
A + + + K ++T E + + ++ + L + + ++
Sbjct: 823 ANKSYTLEGQTKGKKPSRRYTTAETRALLKDMQHAEDTRNMVLKDLARRLFEKFSNHYDQ 882
Query: 603 LEKLSVVTAQLDILCSFAQVSSYAPIPYVRPKMYPLNDQNRTTELIASRHPIVEMQDDVT 662
++ A LD+L S A+ + + V P++ DQ +L HP T
Sbjct: 883 WKQCIDCVANLDVLGSLAEYAGQQMVICV-PELVSDADQP-FIQLEEGYHPCANAS---T 937
Query: 663 FISNDVKL-VQGDSEFIVITGPNMGGKSTYIRQIGVICLMAQI 704
+I N ++L ++ ++TGPNMGGKST +R++G++ +MAQI
Sbjct: 938 YIPNGLELGTASEAPLSLLTGPNMGGKSTLMREVGLLVIMAQI 980
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,128,331
Number of Sequences: 60738
Number of extensions: 2401582
Number of successful extensions: 8499
Number of sequences better than 1.0e-05: 31
Number of HSP's better than 0.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 8360
Number of HSP's gapped (non-prelim): 52
length of query: 956
length of database: 30,389,216
effective HSP length: 116
effective length of query: 840
effective length of database: 23,343,608
effective search space: 19608630720
effective search space used: 19608630720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)