ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0736 good R KOG1577 General function prediction only Aldo/keto reductase family proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0736 249240 250229 330
(330 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR149w [R] KOG1577 Aldo/keto reductase family proteins 427 e-119
YOR120w [R] KOG1577 Aldo/keto reductase family proteins 195 7e-50
7294702 [R] KOG1577 Aldo/keto reductase family proteins 192 7e-49
ECU01g0970 [R] KOG1577 Aldo/keto reductase family proteins 188 1e-47
YDR368w [R] KOG1577 Aldo/keto reductase family proteins 179 4e-45
SPAC26F1.07 [R] KOG1577 Aldo/keto reductase family proteins 179 5e-45
SPBC8E4.04 [R] KOG1577 Aldo/keto reductase family proteins 178 8e-45
At2g37770 [R] KOG1577 Aldo/keto reductase family proteins 177 1e-44
Hs20127592 [R] KOG1577 Aldo/keto reductase family proteins 174 2e-43
At2g37790 [R] KOG1577 Aldo/keto reductase family proteins 172 5e-43
7292407 [R] KOG1577 Aldo/keto reductase family proteins 171 1e-42
Hs5174391 [R] KOG1577 Aldo/keto reductase family proteins 169 7e-42
Hs4502049 [R] KOG1577 Aldo/keto reductase family proteins 168 1e-41
CE21733 [R] KOG1577 Aldo/keto reductase family proteins 167 1e-41
At3g53880 [R] KOG1577 Aldo/keto reductase family proteins 167 1e-41
7298972 [R] KOG1577 Aldo/keto reductase family proteins 167 2e-41
CE24243 [R] KOG1577 Aldo/keto reductase family proteins 166 3e-41
Hs11386205 [R] KOG1577 Aldo/keto reductase family proteins 163 4e-40
7294701 [R] KOG1577 Aldo/keto reductase family proteins 162 5e-40
Hs5453543 [R] KOG1577 Aldo/keto reductase family proteins 160 2e-39
Hs4503285 [R] KOG1577 Aldo/keto reductase family proteins 160 2e-39
At2g37760 [R] KOG1577 Aldo/keto reductase family proteins 159 5e-39
At2g21260 [R] KOG1577 Aldo/keto reductase family proteins 159 5e-39
At2g21250 [R] KOG1577 Aldo/keto reductase family proteins 159 7e-39
CE06776 [R] KOG1577 Aldo/keto reductase family proteins 157 2e-38
Hs13899261 [R] KOG1577 Aldo/keto reductase family proteins 157 3e-38
CE27788 [R] KOG1577 Aldo/keto reductase family proteins 157 3e-38
7294572 [R] KOG1577 Aldo/keto reductase family proteins 156 4e-38
At5g01670 [R] KOG1577 Aldo/keto reductase family proteins 155 6e-38
Hs5174695 [R] KOG1577 Aldo/keto reductase family proteins 154 2e-37
Hs20127601 [R] KOG1577 Aldo/keto reductase family proteins 154 2e-37
7292408 [R] KOG1577 Aldo/keto reductase family proteins 154 2e-37
CE17230 [R] KOG1577 Aldo/keto reductase family proteins 153 4e-37
At5g62420 [R] KOG1577 Aldo/keto reductase family proteins 152 8e-37
CE01200 [R] KOG1577 Aldo/keto reductase family proteins 149 7e-36
Hs17450865 [R] KOG1577 Aldo/keto reductase family proteins 145 1e-34
CE10936 [R] KOG1577 Aldo/keto reductase family proteins 144 2e-34
Hs17465400 [R] KOG1577 Aldo/keto reductase family proteins 141 1e-33
7302301 [R] KOG1577 Aldo/keto reductase family proteins 139 7e-33
YHR104w [R] KOG1577 Aldo/keto reductase family proteins 135 8e-32
7294573 [R] KOG1577 Aldo/keto reductase family proteins 135 1e-31
CE06112 [R] KOG1577 Aldo/keto reductase family proteins 133 4e-31
CE10934 [R] KOG1577 Aldo/keto reductase family proteins 130 3e-30
At1g59960 [R] KOG1577 Aldo/keto reductase family proteins 129 6e-30
At1g59950 [R] KOG1577 Aldo/keto reductase family proteins 128 1e-29
SPAC19G12.09 [R] KOG1577 Aldo/keto reductase family proteins 126 5e-29
Hs22054710 [R] KOG1577 Aldo/keto reductase family proteins 125 1e-28
SPAC2F3.05c [R] KOG1577 Aldo/keto reductase family proteins 123 3e-28
CE24244 [R] KOG1577 Aldo/keto reductase family proteins 120 4e-27
CE15543 [R] KOG1577 Aldo/keto reductase family proteins 117 2e-26
CE06751 [R] KOG1577 Aldo/keto reductase family proteins 116 5e-26
YDL124w [R] KOG1577 Aldo/keto reductase family proteins 114 1e-25
Hs20470761 [R] KOG1577 Aldo/keto reductase family proteins 112 1e-24
SPAP32A8.02 [R] KOG1577 Aldo/keto reductase family proteins 107 2e-23
YJR096w [R] KOG1577 Aldo/keto reductase family proteins 103 3e-22
Hs20545142 [R] KOG1577 Aldo/keto reductase family proteins 103 5e-22
Hs20537171 [R] KOG1577 Aldo/keto reductase family proteins 89 9e-18
Hs16156291 [R] KOG1577 Aldo/keto reductase family proteins 82 1e-15
SPBC28F2.05c [R] KOG1577 Aldo/keto reductase family proteins 79 7e-15
CE06775 [R] KOG1577 Aldo/keto reductase family proteins 71 2e-12
Hs22060498 [R] KOG1577 Aldo/keto reductase family proteins 53 5e-07
Hs22058392 [R] KOG1577 Aldo/keto reductase family proteins 53 5e-07
Hs22048214 [R] KOG1577 Aldo/keto reductase family proteins 52 2e-06
>YBR149w [R] KOG1577 Aldo/keto reductase family proteins
Length = 344
Score = 427 bits (1098), Expect = e-119
Identities = 198/318 (62%), Positives = 254/318 (79%)
Query: 1 MLHPLSTEIYFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVE 60
MLHP +TEIYF+ NNG ++PA GLGTA HE++AETKQAVKAAIKAGYRHIDTAWAY E
Sbjct: 15 MLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETE 74
Query: 61 EYVGEALQELFEERVVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPL 120
+VGEA++EL E+ +KREDL IT+KVW +W++VD+SLNESL L ++YVDL LQHWPL
Sbjct: 75 PFVGEAIKELLEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKALGLEYVDLLLQHWPL 134
Query: 121 CTQKVPDPHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNF 180
C +K+ DP G+ + K PVDD G +Y GD++ETYKQ+EKIYLD ND RVRAIGVSNF
Sbjct: 135 CFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNF 194
Query: 181 PIEYLKRVLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELP 240
IEYL+R++KECR P NQVE HPHLPQ EL +FC H IL+TAYSPLG +GAP L++P
Sbjct: 195 SIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIP 254
Query: 241 ILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEEDVNKLNEFGQ 300
++K L EKYN + ND+L SYH+RQGTIVIPRSLN RI+S++EF L+++++ +LN+FG+
Sbjct: 255 LVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLTKDELQELNDFGE 314
Query: 301 KNKKRYINGAVSSVIPGF 318
K R+I+ ++++P F
Sbjct: 315 KYPVRFIDEPFAAILPEF 332
>YOR120w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 195 bits (496), Expect = 7e-50
Identities = 119/309 (38%), Positives = 183/309 (58%), Gaps = 20/309 (6%)
Query: 6 STEIYFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGE 65
ST+I + N G ++P GLGT E + +AV A+K GYRHIDTA Y E+ VG+
Sbjct: 8 STKI-LSLNTGAQIPQIGLGTWQSKEN--DAYKAVLTALKDGYRHIDTAAIYRNEDQVGQ 64
Query: 66 ALQELFEERVVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKV 125
A+++ V RE++ +T+K+W T ++ + +L++SL RL +DYVDL+L HWP
Sbjct: 65 AIKD----SGVPREEIFVTTKLWCTQHHEPEVALDQSLKRLGLDYVDLYLMHWPARL--- 117
Query: 126 PDPHGV--DKIAKEPVDDQGNPLYD-EKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPI 182
DP + + I P G+ D ++I+T++ +++ L K K +A+GVSNF I
Sbjct: 118 -DPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQE--LPKTGK-TKAVGVSNFSI 173
Query: 183 EYLKRVLKEC--RTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELP 240
LK +L + PA NQVE+HP LPQ EL FC I+V AYSPLG APLL+ P
Sbjct: 174 NNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDAPLLKEP 233
Query: 241 ILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEEDVNKLNEFG- 299
++ + +K N P ++ S+H+++G +V+P+S+N RI +N + LS ED +N
Sbjct: 234 VILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNRKIFTLSTEDFEAINNISK 293
Query: 300 QKNKKRYIN 308
+K +KR ++
Sbjct: 294 EKGEKRVVH 302
>7294702 [R] KOG1577 Aldo/keto reductase family proteins
Length = 302
Score = 192 bits (487), Expect = 7e-49
Identities = 115/298 (38%), Positives = 168/298 (55%), Gaps = 26/298 (8%)
Query: 13 FNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFE 72
FNNG +VP GLGT + + +AVK AI AGYRHID A+ Y E+ VG+ ++ +
Sbjct: 8 FNNGKEVPIIGLGTWGSPK--GQVTEAVKVAIDAGYRHIDCAYVYQNEDEVGDGVEAKIK 65
Query: 73 ERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHG 130
E VVKREDL ITSK+W+T V +L +L+ LK+ Y+DL+L HWP+ ++ G
Sbjct: 66 EGVVKREDLFITSKLWNTFHRPDLVKSALENTLSSLKLKYLDLYLIHWPMGYKE-----G 120
Query: 131 VDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLK 190
D P D G LY D+++T+K +EK+ + V++IGVSNF ++RVL+
Sbjct: 121 CDLF---PTDKDGKTLYSPV-DYVDTWKAMEKLV---EEGLVKSIGVSNFNRRQIERVLE 173
Query: 191 ECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP--------LLELPIL 242
P NQ+E HP+L Q++L +FC I +TAYSPLG P +LE +
Sbjct: 174 VATIPPVTNQIECHPYLTQKKLIDFCKSKDITITAYSPLGSPNRPWAKAGDPVILEEAKI 233
Query: 243 KGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNEF 298
K + K +P IL Y +++ IVIP+S+ RI SN + L+ E++ + F
Sbjct: 234 KEIAAKKKKTPGQILIRYQVQRANIVIPKSVTKDRIESNFQVFDFELTPEEIEIIESF 291
>ECU01g0970 [R] KOG1577 Aldo/keto reductase family proteins
Length = 301
Score = 188 bits (477), Expect = 1e-47
Identities = 112/314 (35%), Positives = 173/314 (54%), Gaps = 24/314 (7%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
NNG ++P GLGT + A + A++ A+ GYRHIDTA+ YG E+ +G L++LF+E
Sbjct: 9 NNGKEIPTVGLGTWGMEDE-AVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDE 67
Query: 74 RVVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVDK 133
VV+R+DL ITSK+W+T + L SL L++DYVDL+L HWP+ PD
Sbjct: 68 GVVQRKDLFITSKLWNTFHGCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPD------ 121
Query: 134 IAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKECR 193
V+ G K D + +K++E + + ++IG+SNF +++L CR
Sbjct: 122 ---GTVESCGKKYNVGKFDAVGVWKKMEALV---DLGLAKSIGISNFGKANTEKILGTCR 175
Query: 194 TVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLG---GNGAPLLELPILKGLCEKYN 250
PA Q+ELHP+L Q+EL EF I V +YS LG G+ A + + +K + +KY
Sbjct: 176 ICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAPGSSAKVRDDKTIKAIAKKYG 235
Query: 251 ASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEEDVNKLNEFGQKNKKRYINGA 310
+P+ I+ SY QG VIP+S + + N++ LS ED++ ++ + RY++
Sbjct: 236 CAPSQIILSYITAQGICVIPKSRSKEHLRENIDLKELSREDISAIDALNTGH--RYVDP- 292
Query: 311 VSSVIPGFKEDFLK 324
PGF + K
Sbjct: 293 -----PGFGPEKFK 301
>YDR368w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 179 bits (455), Expect = 4e-45
Identities = 111/292 (38%), Positives = 168/292 (57%), Gaps = 18/292 (6%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
N G +P G GT + +V AA+KAGYRHID A Y EE VG A+++
Sbjct: 15 NTGASIPVLGFGTWRSVDN--NGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIKD---- 68
Query: 74 RVVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWP--LCTQKVPDPHGV 131
V RE++ IT+K+W T D + +LN+SL RL +DYVDL+L HWP L T +V D +
Sbjct: 69 SGVPREEIFITTKLWGTEQRDPEAALNKSLKRLGLDYVDLYLMHWPVPLKTDRVTDGN-- 126
Query: 132 DKIAKEPVDDQGNPLYDEKG-DWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLK 190
+ P + G D K ++I+T++ +++ L K K +A+GVSNF I +K +L+
Sbjct: 127 --VLCIPTLEDGTVDIDTKEWNFIKTWELMQE--LPKTGK-TKAVGVSNFSINNIKELLE 181
Query: 191 EC--RTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELPILKGLCEK 248
+ VPA NQ+E+HP LPQ EL FC E I+V AYSP G APLL+ + + +K
Sbjct: 182 SPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFGSANAPLLKEQAIIDMAKK 241
Query: 249 YNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEEDVNKLNEFGQ 300
+ P ++ S+ +++G +V+ +S+N RI SN + L E+D ++ +
Sbjct: 242 HGVEPAQLIISWSIQRGYVVLAKSVNPERIVSNFKIFTLPEDDFKTISNLSK 293
>SPAC26F1.07 [R] KOG1577 Aldo/keto reductase family proteins
Length = 321
Score = 179 bits (454), Expect = 5e-45
Identities = 114/302 (37%), Positives = 170/302 (55%), Gaps = 29/302 (9%)
Query: 9 IYFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQ 68
++FT +G+K+P GLGT +TK AVK A++ GYRHID A YG E+ VG+ ++
Sbjct: 14 VHFTLADGSKIPGLGLGTWRSEPN--QTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK 71
Query: 69 ELFEERVVKREDLHITSKVWHTMW--NDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVP 126
E V R+D+ +TSK+W V K+L ++L LK+DY+D +L HWP+ +
Sbjct: 72 E----SGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGE 127
Query: 127 DPHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLK 186
D K P D GN +Y EK ET+K +EK+ +VR IG+SNF L+
Sbjct: 128 D--------KFPKDKDGNLIY-EKNPIEETWKAMEKLL---ETGKVRHIGLSNFNDTNLE 175
Query: 187 RVLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGA-------PLLEL 239
R+LK + PA +Q+ELHP LPQ E E + I VTAYSP G L+E
Sbjct: 176 RILKVAKVKPAVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGNQNTIYESKIPKLIEH 235
Query: 240 PILKGLCEK--YNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEEDVNKLNE 297
++ + + + I S+ + +GT VIP+S+N RI SN +++PL++ED++++N
Sbjct: 236 ETIQKIAKSKGEGVTGATIAVSWAITRGTSVIPKSVNEQRIKSNFKYIPLTKEDMDEINS 295
Query: 298 FG 299
G
Sbjct: 296 IG 297
>SPBC8E4.04 [R] KOG1577 Aldo/keto reductase family proteins
Length = 325
Score = 178 bits (452), Expect = 8e-45
Identities = 113/303 (37%), Positives = 176/303 (57%), Gaps = 29/303 (9%)
Query: 8 EIYFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEAL 67
E YFT NG+K+P+ GLGT + ETK AV AA+KAGYRHIDTA YG E+ +GE +
Sbjct: 12 EAYFTLPNGDKIPSIGLGTWRSGKD--ETKNAVCAALKAGYRHIDTAHIYGNEKEIGEGI 69
Query: 68 QELFEERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKV 125
+E V R D+ +TSK+W V +L ++L L ++Y+D +L HWP
Sbjct: 70 RE----SGVPRTDIWVTSKLWCNAHRAGLVPLALEKTLQDLNLEYIDAYLIHWPFALLSG 125
Query: 126 PDPHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYL 185
P+ + P +++G +Y++ ET++ +E++ +VR IG+SNF EYL
Sbjct: 126 PE--------ELPRNEKGELIYEDV-PIEETWQAMEELL---ETGKVRYIGISNFNNEYL 173
Query: 186 KRVLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGN----GAPLLELPI 241
RVLK + P +Q+ELHP+LPQ E E + +I V+AYSPL + + +L
Sbjct: 174 DRVLKIAKVKPTIHQMELHPYLPQTEYLEKHKKLQIHVSAYSPLANQNDAYNSDISKLIE 233
Query: 242 LKGLCEKYNA-----SPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEEDVNKLN 296
K L + NA +P +I S+ +++GT V+P+S+N +RI SN ++PL+++++ +N
Sbjct: 234 HKTLVDIANARGEGITPANIAISWAVKRGTSVLPKSVNESRIVSNFLYIPLTDKEMEAIN 293
Query: 297 EFG 299
G
Sbjct: 294 NIG 296
>At2g37770 [R] KOG1577 Aldo/keto reductase family proteins
Length = 290
Score = 177 bits (450), Expect = 1e-44
Identities = 116/289 (40%), Positives = 157/289 (54%), Gaps = 26/289 (8%)
Query: 10 YFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQE 69
+F N G K P+ GLGT + AV AA+K GYRHID A YG E+ +G L++
Sbjct: 7 FFKLNTGAKFPSVGLGTWQASPGLVG--DAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKK 64
Query: 70 LFEERVVKREDLHITSKVWHTMWN--DVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPD 127
LFE+RVVKREDL ITSK+W T + DV ++LN +L L+++YVDL+L HWP +K
Sbjct: 65 LFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK--G 122
Query: 128 PHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKR 187
G+ PVD T+K +E +Y + + RAIGVSNF + L
Sbjct: 123 SVGIKPENLLPVDIP------------STWKAMEALY---DSGKARAIGVSNFSTKKLAD 167
Query: 188 VLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNG-----APLLELPIL 242
+L+ R PA NQVE HP Q +L EFC + ++AYSPLG G + +L+ PIL
Sbjct: 168 LLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPIL 227
Query: 243 KGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEED 291
+ EK SP + + L+ G V+P+S N RI N S D
Sbjct: 228 NMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPD 276
>Hs20127592 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 174 bits (441), Expect = 2e-43
Identities = 108/297 (36%), Positives = 168/297 (56%), Gaps = 28/297 (9%)
Query: 18 KVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEERVVK 77
K+P GLGT + + K+AVK AI AGYRHID A+ Y E VGEA+QE +E+ VK
Sbjct: 12 KMPIVGLGT--WKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVK 69
Query: 78 REDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVDKIA 135
REDL I SK+W T + V K+ ++L LK+ Y+D++L HWP + D
Sbjct: 70 REDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLF------ 123
Query: 136 KEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKE--CR 193
P DD+GN + K +++ ++ +E++ ++ V+A+GVSNF ++++L + +
Sbjct: 124 --PKDDKGNAI-GGKATFLDAWEAMEELV---DEGLVKALGVSNFSHFQIEKLLNKPGLK 177
Query: 194 TVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP--------LLELPILKGL 245
P NQVE HP+L Q +L ++C I VTAYSPLG P LLE P +K +
Sbjct: 178 YKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEI 237
Query: 246 CEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNEFGQ 300
K+ + +L +H+++ IVIP+S+ RI N++ LS+E++ + F +
Sbjct: 238 AAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNR 294
>At2g37790 [R] KOG1577 Aldo/keto reductase family proteins
Length = 350
Score = 172 bits (437), Expect = 5e-43
Identities = 108/300 (36%), Positives = 162/300 (54%), Gaps = 28/300 (9%)
Query: 10 YFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQE 69
+F N G K+P+ GLGT + AV AA+K GYRHID A YG E+ +G L++
Sbjct: 7 FFELNTGAKIPSVGLGTWQADPGLVGN--AVDAAVKIGYRHIDCAQIYGNEKEIGLVLKK 64
Query: 70 LFEERVVKREDLHITSKVWHTMWN--DVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPD 127
LF+ VVKRE++ ITSK+W T + +V ++LN +L L++DYVDL+L HWP+ +K
Sbjct: 65 LFDGGVVKREEMFITSKLWCTYHDPQEVPEALNRTLQDLQLDYVDLYLIHWPVSLKKGST 124
Query: 128 PHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKR 187
+ I + T+K +E ++ + + RAIGVSNF + L
Sbjct: 125 GFKPENILPTDIP--------------STWKAMESLF---DSGKARAIGVSNFSSKKLAD 167
Query: 188 VLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNG-----APLLELPIL 242
+L R PA NQVE HP Q L +FC + ++ YSPLG G + +L+ PIL
Sbjct: 168 LLVVARVPPAVNQVECHPSWQQNVLRDFCKSKGVHLSGYSPLGSPGTTWLTSDVLKNPIL 227
Query: 243 KGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFV--PLSEEDVNKLNEFGQ 300
G+ EK +P + + L+ G V+P+S + RI N + + E+ ++K +E GQ
Sbjct: 228 GGVAEKLGKTPAQVALRWGLQMGQSVLPKSTHEDRIKQNFDVFNWSIPEDMLSKFSEIGQ 287
>7292407 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 171 bits (433), Expect = 1e-42
Identities = 112/315 (35%), Positives = 168/315 (52%), Gaps = 21/315 (6%)
Query: 8 EIYFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEAL 67
E YF N+G + GLGT A E + ++AV AI GYRHIDTA+ YG E VG A+
Sbjct: 6 EYYFKHNDGTHIQGIGLGTFASTE--GDCERAVLHAIDVGYRHIDTAYFYGNEAEVGAAV 63
Query: 68 QELFEERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKV 125
++ E V+KRED+ IT+K+W V+ + ++L + +DYVDL+L HWP +
Sbjct: 64 RKKIAEGVIKREDIFITTKLWCNFHEPERVEYACRKTLKNIGLDYVDLYLIHWPFSYKYR 123
Query: 126 PDPHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYL 185
D + K A V+ L D D+++T+ +EK+ + ++IGVSNF E L
Sbjct: 124 GDNELIPKDANGEVE-----LVDI--DYLDTWGAMEKLV---DLGLTKSIGVSNFNEEQL 173
Query: 186 KRVLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELPIL--- 242
R+L C+ P NQ+E+HP L Q++L C ++ ILVTA+SPLG + A L +
Sbjct: 174 TRLLANCKIKPIHNQIEVHPALDQKKLIALCKKNGILVTAFSPLGRHNAELRTPTFMYDG 233
Query: 243 --KGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNEF 298
+ + +KYN S ++ Y + GTI +P+S N RI N L ED L+ +
Sbjct: 234 KVQAIADKYNKSIAQVVIRYVIELGTIPLPKSSNPKRIEENFNVFDFKLDAEDHAILDSY 293
Query: 299 GQKNKKRYINGAVSS 313
+ + A+ S
Sbjct: 294 HNGERVAHARQAIKS 308
>Hs5174391 [R] KOG1577 Aldo/keto reductase family proteins
Length = 325
Score = 169 bits (427), Expect = 7e-42
Identities = 109/300 (36%), Positives = 161/300 (53%), Gaps = 30/300 (10%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQE-LFE 72
+ G K+P GLGT + K AVK A+ GYRHID A YG E +GEAL+E +
Sbjct: 9 HTGQKMPLIGLGTWKSEP--GQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGP 66
Query: 73 ERVVKREDLHITSKVWHTMWN--DVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHG 130
+ V RE+L +TSK+W+T + DV+ +L ++LA L+++Y+DL+L HWP ++ +P
Sbjct: 67 GKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPF- 125
Query: 131 VDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLK 190
P + G YD + ET+K +E + V+A+G+SNF + +L
Sbjct: 126 -------PKNADGTICYDST-HYKETWKALEALVAKG---LVQALGLSNFNSRQIDDILS 174
Query: 191 ECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP--------LLELPIL 242
PA QVE HP+L Q EL C + VTAYSPLG + LLE P++
Sbjct: 175 VASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVV 234
Query: 243 KGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLE-----FVPLSEEDVNKLNE 297
L EKY SP IL + +++ I IP+S+ +RI N++ F P + +N LN+
Sbjct: 235 LALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK 294
>Hs4502049 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 168 bits (425), Expect = 1e-41
Identities = 114/325 (35%), Positives = 174/325 (53%), Gaps = 32/325 (9%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
NNG K+P GLGT + +AVK AI GYRHID A Y E VG A+QE E
Sbjct: 8 NNGAKMPILGLGTWKSPP--GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLRE 65
Query: 74 RVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGV 131
+VVKRE+L I SK+W T V + ++L+ LK+DY+DL+L HWP
Sbjct: 66 QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF--------- 116
Query: 132 DKIAKE--PVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVL 189
K KE P+D+ GN + + + ++T+ +E++ ++ V+AIG+SNF ++ +L
Sbjct: 117 -KPGKEFFPLDESGNVVPSDT-NILDTWAAMEELV---DEGLVKAIGISNFNHLQVEMIL 171
Query: 190 KE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP--------LLEL 239
+ + PA NQ+E HP+L Q +L ++C I+VTAYSPLG P LLE
Sbjct: 172 NKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLED 231
Query: 240 PILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNE 297
P +K + K+N + +L + +++ +VIP+S+ RIA N + LS +D+ L
Sbjct: 232 PRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLS 291
Query: 298 FGQKNKKRYINGAVSSVIPGFKEDF 322
+ + + + S F E+F
Sbjct: 292 YNRNWRVCALLSCTSHKDYPFHEEF 316
>CE21733 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 167 bits (424), Expect = 1e-41
Identities = 106/297 (35%), Positives = 163/297 (54%), Gaps = 29/297 (9%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
N+G +PA GLGT + E A+K A+ AGYRHID A Y ++ VGEAL+E+ +E
Sbjct: 8 NSGYSIPAIGLGT--WQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDE 65
Query: 74 RVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGV 131
VKRE+L ITSKVW+T ++ ++++ L+ L++ YVDL L HW P G
Sbjct: 66 GKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHW---------PQGY 116
Query: 132 DKIAK-EPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLK 190
+ A+ P + G Y + D++ET+K E + + R+IG+SNF ++RV
Sbjct: 117 AEGAELFPAGENGKMRYSDV-DYLETWKAFEAA---QKAGKCRSIGLSNFTHSQIQRVWD 172
Query: 191 ECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP---------LLELPI 241
PAC QVELHP+ Q +L EFC E I+V YSPLG G+ +L +
Sbjct: 173 AAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNEV 232
Query: 242 LKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLN 296
+ G+ + + +P I+ + + G IP+S+ RI+ NL L+ E+++K++
Sbjct: 233 VAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRISENLAVFDFQLTAEEISKID 289
>At3g53880 [R] KOG1577 Aldo/keto reductase family proteins
Length = 315
Score = 167 bits (424), Expect = 1e-41
Identities = 109/307 (35%), Positives = 163/307 (52%), Gaps = 27/307 (8%)
Query: 10 YFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQE 69
+F N G K+P+ GLGT V AV AA+K GY+HID A YG E +G+ L++
Sbjct: 7 FFQLNTGAKIPSVGLGTWQAAPGVVG--DAVAAAVKIGYQHIDCASRYGNEIEIGKVLKK 64
Query: 70 LFEERVVKREDLHITSKVWHTMWN--DVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPD 127
LF++ VVKRE L ITSK+W T + DV +LN +L L++DYVDL+L HWP+ +K
Sbjct: 65 LFDDGVVKREKLFITSKIWLTDLDPPDVQDALNRTLQDLQLDYVDLYLMHWPVRLKKGTV 124
Query: 128 PHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKR 187
+ I P+D T+K +E + + + RAIGVSNF + L
Sbjct: 125 DFKPENIM--PIDIPS------------TWKAMEALV---DSGKARAIGVSNFSTKKLSD 167
Query: 188 VLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNG-----APLLELPIL 242
+++ R PA NQVE HP Q +L EFC I ++ YSPLG G A +L+ P++
Sbjct: 168 LVEAARVPPAVNQVECHPSWQQHKLHEFCKSKGIHLSGYSPLGSPGTTWVKADVLKSPVI 227
Query: 243 KGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEEDVNKLNEFGQKN 302
+ + ++ SP + L+ G ++P+S N RI N + + S ++F +
Sbjct: 228 EMIAKEIGKSPAQTALRWGLQMGHSILPKSTNEGRIRENFDVLGWSIPK-EMFDKFSKIE 286
Query: 303 KKRYING 309
+ R + G
Sbjct: 287 QARLVQG 293
>7298972 [R] KOG1577 Aldo/keto reductase family proteins
Length = 329
Score = 167 bits (423), Expect = 2e-41
Identities = 108/309 (34%), Positives = 163/309 (51%), Gaps = 30/309 (9%)
Query: 10 YFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQE 69
+ TFNNG K+P G+GT + ET A+ AA++AGYRHIDTA YG E+ +G L+
Sbjct: 6 FLTFNNGEKMPVIGIGTWQASDEEIET--AIDAALEAGYRHIDTAPVYGNEKAIGRVLKR 63
Query: 70 LFEERVVKREDLHITSKV--WHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPD 127
+ VKRE+L I +KV ++V+ ++ +SL L++DYVDL+L H P D
Sbjct: 64 WLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININED 123
Query: 128 PHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKR 187
G K+ KE + + + + W+ +EK ++IGVSNF + + R
Sbjct: 124 --GSFKLDKEGLMEV-DVTTNHAAIWVAMEALVEK-------GLTKSIGVSNFSKDQVAR 173
Query: 188 VLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNG-------------- 233
+LK C+ PA NQ+E H +L QR+L +FC I VTAYSPLG G
Sbjct: 174 LLKNCKIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDL 233
Query: 234 APLLELPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEED 291
L+++P +K + + +P +L + + G IP+S N R+ NL+ L+ E+
Sbjct: 234 PDLMDIPEVKEIAASHGKTPAQVLLRWIIDTGVSAIPKSTNPARLKQNLDVFDFELTAEE 293
Query: 292 VNKLNEFGQ 300
V KL+ Q
Sbjct: 294 VAKLSSLDQ 302
>CE24243 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 166 bits (421), Expect = 3e-41
Identities = 105/297 (35%), Positives = 161/297 (53%), Gaps = 29/297 (9%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
N+G +PA GLGT + E A+K A+ AGYRHID A Y ++ VGEAL+E+ +E
Sbjct: 8 NSGYSIPAIGLGT--WQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKEILDE 65
Query: 74 RVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGV 131
VKRE+L ITSKVW+T ++ ++++ L+ L++ YVDL L HW P G
Sbjct: 66 GKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHW---------PQGY 116
Query: 132 DKIAK-EPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLK 190
+ A+ P + G Y + D++ET+K E + + R+IG+SNF ++RV
Sbjct: 117 AEGAELFPAGENGKMRYSDV-DYLETWKAFEAA---QKAGKCRSIGLSNFTHSQIQRVWD 172
Query: 191 ECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP---------LLELPI 241
PAC QVELHP+ Q +L EFC E I+V YSPLG G+ +L +
Sbjct: 173 AAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNEV 232
Query: 242 LKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFV--PLSEEDVNKLN 296
+ G+ + + +P I+ + + G IP+S+ RI N+ + LS E++ ++
Sbjct: 233 VAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRIIENISVIDFQLSAEEIQAID 289
>Hs11386205 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 163 bits (412), Expect = 4e-40
Identities = 109/310 (35%), Positives = 165/310 (53%), Gaps = 30/310 (9%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETK-QAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFE 72
N+G+ +P G GT A E + K AI+AG+RHID+A+ Y EE VG A++
Sbjct: 11 NDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIA 70
Query: 73 ERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHG 130
+ VKRED+ TSK+W T + V +L SL +L++DYVDL+L H+P+ + P
Sbjct: 71 DGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETP-- 128
Query: 131 VDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLK 190
P D+ G ++D D T++ +EK K+ ++IGVSNF L+ +L
Sbjct: 129 ------LPKDENGKVIFDTV-DLSATWEVMEKC---KDAGLAKSIGVSNFNCRQLEMILN 178
Query: 191 E--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLG---------GNGAPLLEL 239
+ + P CNQVE HP+L Q +L +FC I++ A+S LG N LLE
Sbjct: 179 KPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLED 238
Query: 240 PILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNE 297
P+L L +K+ +P I Y L++G +V+ +S N RI N++ L+ ED+ L+
Sbjct: 239 PVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLD- 297
Query: 298 FGQKNKKRYI 307
G RY+
Sbjct: 298 -GLNRNYRYV 306
>7294701 [R] KOG1577 Aldo/keto reductase family proteins
Length = 305
Score = 162 bits (411), Expect = 5e-40
Identities = 106/300 (35%), Positives = 157/300 (52%), Gaps = 25/300 (8%)
Query: 11 FTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQEL 70
F +NG +P GLGT V QAVK AI GYRH D A YG E VG AL+E
Sbjct: 6 FLLSNGKNMPMLGLGTWRSPPEVVT--QAVKDAIDIGYRHFDCAHIYGNEAQVGAALREK 63
Query: 71 FEERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDP 128
+E VV R++L ITSK+W+T V + S+ L V Y++L+L HWP+ +
Sbjct: 64 MDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKS---- 119
Query: 129 HGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRV 188
G D + P N E D+++T++ +E + ++ +AIGVSNF + + R+
Sbjct: 120 -GSDNL--YPTCPDTNKAAFEDIDYVDTWRAMENLV---DEGLCQAIGVSNFNEQQMNRL 173
Query: 189 LKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGN-------GA-PLLELP 240
L + P Q+E HP+L Q+ L C ++ I VTAYS LG GA PLL+ P
Sbjct: 174 LSVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHP 233
Query: 241 ILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFV---PLSEEDVNKLNE 297
+ + EKY + +L + + G IVIPRS++ + N + + L+ +D+ +NE
Sbjct: 234 TILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINE 293
>Hs5453543 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 160 bits (406), Expect = 2e-39
Identities = 112/295 (37%), Positives = 161/295 (53%), Gaps = 31/295 (10%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETK--QAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELF 71
N+G+ +P G GT A E V ++K +A K AI+AG+RHID+A Y EE VG A++
Sbjct: 11 NDGHFMPVLGFGTYAPAE-VPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 72 EERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPH 129
+ VKRED+ TSK+W V +L SL L++DYVDL+L H+P+ +
Sbjct: 70 ADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP----- 124
Query: 130 GVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVL 189
G + I P D+ G L+D D T++ +EK K+ ++IGVSNF L+ +L
Sbjct: 125 GEEVI---PKDENGKILFDTV-DLCATWEAVEKC---KDAGLAKSIGVSNFNRRQLEMIL 177
Query: 190 KE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGG---------NGAPLLE 238
+ + P CNQVE HP+ QR+L +FC I++ AYS LG N LLE
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLE 237
Query: 239 LPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNL---EFVPLSEE 290
P+L L +K+ +P I Y L++G +V+ +S N RI N+ EF SEE
Sbjct: 238 DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEE 292
>Hs4503285 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 160 bits (406), Expect = 2e-39
Identities = 112/295 (37%), Positives = 161/295 (53%), Gaps = 31/295 (10%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETK--QAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELF 71
N+G+ +P G GT A E V ++K +AVK AI+AG+ HID+A Y EE VG A++
Sbjct: 11 NDGHFMPVLGFGTYAPAE-VPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKI 69
Query: 72 EERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPH 129
+ VKRED+ TSK+W V +L SL L++DYVDL+L H+P+ +
Sbjct: 70 ADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKP----- 124
Query: 130 GVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVL 189
G + I P D+ G L+D D T++ +EK K+ ++IGVSNF L+ +L
Sbjct: 125 GEEVI---PKDENGKILFDTV-DLCATWEAMEKC---KDAGLAKSIGVSNFNHRLLEMIL 177
Query: 190 KE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGG---------NGAPLLE 238
+ + P CNQVE HP+ QR+L +FC I++ AYS LG N LLE
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLE 237
Query: 239 LPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNL---EFVPLSEE 290
P+L L +K+ +P I Y L++G +V+ +S N RI N+ EF SEE
Sbjct: 238 DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEE 292
>At2g37760 [R] KOG1577 Aldo/keto reductase family proteins
Length = 294
Score = 159 bits (402), Expect = 5e-39
Identities = 102/284 (35%), Positives = 147/284 (50%), Gaps = 36/284 (12%)
Query: 10 YFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQE 69
+F N G K+P GLGT A A++ AIK GYRHID A YG E+ +G L++
Sbjct: 7 FFELNTGAKLPCVGLGTYAM------VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 60
Query: 70 LFEERVVKREDLHITSKVWHT--MWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQK--- 124
L + VKRE+L ITSK+W + DV K+L ++L L++DYVDL+L HWP +K
Sbjct: 61 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKKESL 120
Query: 125 VPDPHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEY 184
+P P + K D T+K +E +Y + + RAIGVSNF +
Sbjct: 121 MPTPEMLTK-----------------PDITSTWKAMEALY---DSGKARAIGVSNFSSKK 160
Query: 185 LKRVLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNG-----APLLEL 239
L +L R PA NQVE HP Q+ L E C + ++ YSPLG +L+
Sbjct: 161 LTDLLNVARVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQN 220
Query: 240 PILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLE 283
PI+ + EK + + + L+ G V+P+S + R+ NL+
Sbjct: 221 PIVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLD 264
>At2g21260 [R] KOG1577 Aldo/keto reductase family proteins
Length = 309
Score = 159 bits (402), Expect = 5e-39
Identities = 102/291 (35%), Positives = 155/291 (53%), Gaps = 20/291 (6%)
Query: 12 TFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELF 71
T N+G K+P GLG + E + + AIK GYRH+D A Y E VGEAL E F
Sbjct: 4 TLNSGFKMPIIGLGVWRMEKE--ELRDLIIDAIKIGYRHLDCAANYKNEAEVGEALTEAF 61
Query: 72 EERVVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGV 131
+VKREDL IT+K+W + V ++ +SL +L++DY+DLFL H P+ T+ H
Sbjct: 62 TTGLVKREDLFITTKLWSSDHGHVIEACKDSLKKLQLDYLDLFLVHIPIATK-----HTG 116
Query: 132 DKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKE 191
+ D G D T+ +EK+ + VR+IG+SN+ + + L
Sbjct: 117 IGTTDSALGDDGVLDIDTTISLETTWHDMEKLV---SMGLVRSIGISNYDVFLTRDCLAY 173
Query: 192 CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGA--------PLLELPILK 243
+ PA NQ+E HP+ + L +FC +H I VTA++PLGG A L+ P+LK
Sbjct: 174 SKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGATANAEWFGTVSCLDDPVLK 233
Query: 244 GLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDV 292
+ EKY + I+ + +++ T+VIP++ R+ N + LS+ED+
Sbjct: 234 DVAEKYKQTVAQIVLRWGIQRNTVVIPKTSKPERLEENFQVFDFQLSKEDM 284
>At2g21250 [R] KOG1577 Aldo/keto reductase family proteins
Length = 309
Score = 159 bits (401), Expect = 7e-39
Identities = 100/300 (33%), Positives = 160/300 (53%), Gaps = 20/300 (6%)
Query: 12 TFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELF 71
T N+G K+P GLG + + + AIK GYRH+D A Y E VG+AL E F
Sbjct: 4 TLNSGFKMPIVGLGVWRMEKE--GIRDLILNAIKIGYRHLDCAADYRNETEVGDALTEAF 61
Query: 72 EERVVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGV 131
+ +VKREDL IT+K+W++ V ++ +SL +L++DY+DLFL H+P+ T+ H
Sbjct: 62 KTGLVKREDLFITTKLWNSDHGHVIEACKDSLKKLQLDYLDLFLVHFPVATK-----HTG 116
Query: 132 DKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKE 191
+ D G D T+ +EK+ + VR+IG+SN+ + + L
Sbjct: 117 VGTTDSALGDDGVLDIDTTISLETTWHDMEKLV---SMGLVRSIGISNYDVFLTRDCLAY 173
Query: 192 CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGA--------PLLELPILK 243
+ PA NQ+E HP+ + L +FC +H I VTA++PLGG A L+ P+LK
Sbjct: 174 SKIKPAVNQIETHPYFQRDSLVKFCQKHGICVTAHTPLGGATANAEWFGTVSCLDDPVLK 233
Query: 244 GLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNEFGQK 301
+ EKY + ++ + +++ T+VIP++ R+ N + LS+ED+ + +K
Sbjct: 234 DVAEKYKKTVAQVVLRWGIQRKTVVIPKTSKPARLEENFQVFDFELSKEDMEVIKSMERK 293
>CE06776 [R] KOG1577 Aldo/keto reductase family proteins
Length = 317
Score = 157 bits (397), Expect = 2e-38
Identities = 111/313 (35%), Positives = 157/313 (49%), Gaps = 47/313 (15%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
+NG ++P GLGT AE AVK A+KAGYR IDTA Y EE +G A++EL EE
Sbjct: 11 SNGVEMPVIGLGT--WQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGTAIKELLEE 68
Query: 74 RVVKREDLHITSKVW-HTMW-NDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGV 131
VVKRE+L IT+K W H + ++ L ESL +L+++YVDL+L H P H
Sbjct: 69 GVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFNDDMSEH-- 126
Query: 132 DKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKE 191
PV+D ++Q + +Y +A+GVSN+ + + R L
Sbjct: 127 ---IASPVED--------------VWRQFDAVY---KAGLAKAVGVSNWNNDQISRALAL 166
Query: 192 CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELPI---------- 241
T +QVELH + PQ + +FC +H I VT+Y+ LG G LP
Sbjct: 167 GLTPVHNSQVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAP 226
Query: 242 -------LKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDV 292
+ L EK + +P +L Y L +G ++P+S+ RI N E L+EED+
Sbjct: 227 SDLQDQNVLALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTEEDI 286
Query: 293 NKLNEFGQKNKKR 305
KL E KN +R
Sbjct: 287 AKLEE--SKNSQR 297
>Hs13899261 [R] KOG1577 Aldo/keto reductase family proteins
Length = 307
Score = 157 bits (396), Expect = 3e-38
Identities = 102/298 (34%), Positives = 164/298 (54%), Gaps = 29/298 (9%)
Query: 19 VPAFGLGT-AAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEERVVK 77
+PA GL + A +V E AVK AI AGYRH D A+ Y E VG ++ +E V+
Sbjct: 4 IPAVGLSSWKASPGKVTE---AVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60
Query: 78 REDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGV---- 131
REDL I +K+W T V+ + +SL LK++Y+DL+L HWP+ K P P +
Sbjct: 61 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM-GFKPPHPEWIMSCS 119
Query: 132 --------DKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIE 183
++ P+ D+ N + D+++T++ +E + + V+ IGVSNF E
Sbjct: 120 ELSFCLSHPRVQDLPL-DESNMVIPSDTDFLDTWEAMEDLVI---TGLVKNIGVSNFNHE 175
Query: 184 YLKRVLKE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGN--GAPLLEL 239
L+R+L + R P NQ+E HP+L Q+ L FC + VTAY PLGG+ G L++
Sbjct: 176 QLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDN 235
Query: 240 PILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKL 295
P++K + +++ SP IL + +++ IVIP S+ + I N++ L++ D++ +
Sbjct: 236 PVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293
>CE27788 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 157 bits (396), Expect = 3e-38
Identities = 111/318 (34%), Positives = 164/318 (50%), Gaps = 47/318 (14%)
Query: 11 FTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQEL 70
FT +NG +P+ GLGT E K ++ A+ AGYRHIDTA Y E +G+AL EL
Sbjct: 8 FTLSNGVLMPSIGLGTWQMTGE--EGKTVIRNAVLAGYRHIDTATLYQNEHQIGDALAEL 65
Query: 71 FEERVVKREDLHITSKVW-HTMWND-VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDP 128
F E ++KRED+ IT+K + H + D V+++L SL RL++DYVDL+L H P T+
Sbjct: 66 FAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTK----- 120
Query: 129 HGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRV 188
D G+ D K + + ++ EK+Y +AIGVSNF + R+
Sbjct: 121 ------------DDGSFRSDVKVE--DIWRGFEKVY---GLGLTKAIGVSNFNESQIVRI 163
Query: 189 LKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPL---------GGNGAPLLEL 239
+ + +Q+ELH +LPQ+ E C +H IL+TAY+ L G NG PL E
Sbjct: 164 MNIQKVPIHASQLELHLYLPQKAHRELCKKHNILITAYATLGSPGRMSVVGSNGRPLFES 223
Query: 240 ----------PILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVP--L 287
+K L +KY+ +P IL + G IVIP++ N R+ N+ +
Sbjct: 224 TQNSENEMNDKHVKALAQKYSKTPAQILLRATVEMGIIVIPKTTNPERMKENINIFDFNI 283
Query: 288 SEEDVNKLNEFGQKNKKR 305
S +VN L + ++R
Sbjct: 284 SNAEVNLLEAHERTKQER 301
>7294572 [R] KOG1577 Aldo/keto reductase family proteins
Length = 317
Score = 156 bits (394), Expect = 4e-38
Identities = 99/277 (35%), Positives = 148/277 (52%), Gaps = 19/277 (6%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
NNG ++P GLGT + E AVK AI GYRHIDTA+ Y E VG+A+++ E
Sbjct: 10 NNGYEMPILGLGTYNSKDNEGEA--AVKHAIDVGYRHIDTAYFYQNEAEVGKAIRDKIAE 67
Query: 74 RVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGV 131
VVKRED+ + +K+W+ + V+ + L+ +DY+DL+L H P+ + V D +
Sbjct: 68 GVVKREDIFLVTKLWNIFHDPERVEGICRKQLSNFGLDYIDLYLMHMPVGYKYVDDNTLL 127
Query: 132 DKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKE 191
K ++ + L D+++TYK +EK+ VR+IGVSNF E L RVL
Sbjct: 128 PK-------NEDDVLQLSDVDYLDTYKAMEKLV---KLGLVRSIGVSNFNSEQLARVLAN 177
Query: 192 CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGG-----NGAPLLELPILKGLC 246
C P NQVE P L Q+ L FC ++ + +T Y+PLG + P + +
Sbjct: 178 CEIKPVTNQVECSPALNQKALTAFCKKNDVTLTGYTPLGKPKPDIQKPDFIYSPEVAVIA 237
Query: 247 EKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLE 283
+KY + I+ Y + G I IP+S N+ RI+ N +
Sbjct: 238 KKYGKTTPQIVLRYLVGLGVIPIPKSSNTNRISENFD 274
>At5g01670 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 155 bits (393), Expect = 6e-38
Identities = 106/306 (34%), Positives = 164/306 (52%), Gaps = 31/306 (10%)
Query: 11 FTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQEL 70
F +G+K+PA GLGT + A V A ++ GYRHIDTAW YG + VG+ ++
Sbjct: 16 FRLLSGHKIPAVGLGTWRSGSQAAHA--VVTAIVEGGYRHIDTAWEYGDQREVGQGIKRA 73
Query: 71 FEERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDP 128
+ +R DL +TSK+W T + V +L +L L+++Y+DL+L HWP+ ++
Sbjct: 74 MHAGL-ERRDLFVTSKLWCTELSPERVRPALQNTLKELQLEYLDLYLIHWPIRLRE---- 128
Query: 129 HGVDKIAKEPVDDQGNPL-YDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKR 187
G K K G+ L +D +G W +++E + D VR IGV NF + L +
Sbjct: 129 -GASKPPKA-----GDVLDFDMEGVW----REMENL---SKDSLVRNIGVCNFTVTKLNK 175
Query: 188 VLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGG--NGAPLLELPILKGL 245
+L +PA Q+E+HP + EFC +++I AYSPLG G L+ + +
Sbjct: 176 LLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEI--HAYSPLGSQEGGRDLIHDQTVDRI 233
Query: 246 CEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVP--LSEEDVNKLNEFGQKNK 303
+K N +P IL + L++GT VIP+SLN RI N++ + E+D LN ++
Sbjct: 234 AKKLNKTPGQILVKWGLQRGTSVIPKSLNPERIKENIKVFDWVIPEQDFQALNSI--TDQ 291
Query: 304 KRYING 309
KR I+G
Sbjct: 292 KRVIDG 297
>Hs5174695 [R] KOG1577 Aldo/keto reductase family proteins
Length = 326
Score = 154 bits (388), Expect = 2e-37
Identities = 105/306 (34%), Positives = 166/306 (53%), Gaps = 36/306 (11%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQA--VKAAIKAGYRHIDTAWAYGVEEYVGEALQELF 71
++GN +P GLGT ++ + + A VK AI GYRHID A+ Y E VGEA++E
Sbjct: 13 SDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKI 72
Query: 72 EERVVKREDLHITSKVWHTMWNDVDKSLNESLAR----LKVDYVDLFLQHWPLCTQKVPD 127
E V+RED+ K+W T N V + + +L R L++DYVDL++ P+ + +
Sbjct: 73 AEGKVRREDIFYCGKLWAT--NHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE 130
Query: 128 PHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKR 187
+ P D+ G LY K + T++ +E K+ V+++GVSNF L+
Sbjct: 131 IY--------PRDENGKWLY-HKSNLCATWEAMEAC---KDAGLVKSLGVSNFNRRQLEL 178
Query: 188 VLKE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGG---------NGAPL 236
+L + + P NQVE HP+ Q +L +FC +H I++TAYSPLG + PL
Sbjct: 179 ILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPL 238
Query: 237 LELPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEE---D 291
L+ +L L ++YN + I+ +++++G +VIP+S N RI N + L+EE D
Sbjct: 239 LKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKD 298
Query: 292 VNKLNE 297
+ LN+
Sbjct: 299 IEALNK 304
>Hs20127601 [R] KOG1577 Aldo/keto reductase family proteins
Length = 323
Score = 154 bits (388), Expect = 2e-37
Identities = 107/312 (34%), Positives = 162/312 (51%), Gaps = 32/312 (10%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETK--QAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELF 71
N+G+ +P G GT A E V +K + K AI+AG+RHID+A Y EE VG A++
Sbjct: 11 NDGHFMPVLGFGTYAPPE-VPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
Query: 72 EERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPH 129
+ VKRED+ TSK+W T V +L SL + ++DYVDL+L H P+ + +
Sbjct: 70 ADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE-- 127
Query: 130 GVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVL 189
P D+ G ++D D T++ +EK K+ ++IGVSNF L+ +L
Sbjct: 128 ------LSPTDENGKVIFDIV-DLCTTWEAMEKC---KDAGLAKSIGVSNFNRRQLEMIL 177
Query: 190 KE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGG---------NGAPLLE 238
+ + P CNQVE HP+ + +L +FC I++ AYS LG N LLE
Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLE 237
Query: 239 LPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLN 296
P+L L +K+ +P I Y L++G +V+ +S N RI N++ L+ ED+ ++
Sbjct: 238 DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAID 297
Query: 297 EFGQKNKKRYIN 308
G Y N
Sbjct: 298 --GLDRNLHYFN 307
>7292408 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 154 bits (388), Expect = 2e-37
Identities = 108/323 (33%), Positives = 163/323 (50%), Gaps = 23/323 (7%)
Query: 10 YFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQE 69
Y NNG ++ + GLGT + ++A AI GYRHIDTA+ Y E VG A+Q
Sbjct: 7 YVKHNNGTQIQSIGLGTYTSLG--GDCERATLHAIDVGYRHIDTAYFYENENEVGAAVQR 64
Query: 70 LFEERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPD 127
E V+KRED+HIT+K+W V+ + ++L + YVDL+L HWP D
Sbjct: 65 KIAEGVIKREDIHITTKLWCHFHEPKRVEYACRKTLQNFGLQYVDLYLMHWPYSYVYRGD 124
Query: 128 PHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKR 187
+ AK V+ L D D+++T++++EK+ ++IGVSNF E L R
Sbjct: 125 NEMMPTDAKGEVE-----LNDI--DYLDTWREMEKLV---ELGLTKSIGVSNFNSEQLTR 174
Query: 188 VLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELP------I 241
+L C+ P NQ+E HP L Q++L C ++ I+VTAY PL G P + P
Sbjct: 175 LLANCKIKPIHNQIECHPALNQKKLIALCKKNDIVVTAYCPL-GRPNPAEKTPNYIYDAK 233
Query: 242 LKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNEFG 299
++ + +KY S ++ Y + GTI +P+S N RI N + L ED L+ +
Sbjct: 234 VQAIGDKYKKSTAQVVLRYLIEIGTIPLPKSSNPKRIEENFQIFDFQLDAEDHAILDSYN 293
Query: 300 QKNKKRYINGAVSSVIPGFKEDF 322
+ + A+ S F +F
Sbjct: 294 TGERLIPMTHAIKSKNYPFNIEF 316
>CE17230 [R] KOG1577 Aldo/keto reductase family proteins
Length = 333
Score = 153 bits (386), Expect = 4e-37
Identities = 108/307 (35%), Positives = 159/307 (51%), Gaps = 30/307 (9%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
N G ++P FGLGT Q + AE A++AA+ AGYR IDTA Y E +G+ L E
Sbjct: 9 NTGAQLPLFGLGTW-QVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVLHEYISS 67
Query: 74 RVVKREDLHITSKVWHTMW--NDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGV 131
+KRED+ +TSK+ T DV K + L L+++Y+DL+L H P P H
Sbjct: 68 GKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPF-----PFKHQE 122
Query: 132 DKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKE 191
A P+ + G E I+T++ +EK+Y + +++A+GVSNF L+ +
Sbjct: 123 GSFA--PLMENGELAVTEIAH-IDTWRALEKLY---KEGKLKALGVSNFSCNQLQALYDA 176
Query: 192 CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGG-------------NGAPLLE 238
PA QVE H + PQ+EL C + + VTAY+PLG G PLLE
Sbjct: 177 AEVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPGRKAARPDGVWPEGDPLLE 236
Query: 239 LPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLN 296
PI+K L KY+ + IL + + G IP+S++ RI N+ LS+ED++ LN
Sbjct: 237 -PIVKQLAAKYHKTAAQILIRHLTQHGISTIPKSVSPDRIVENISTFDFKLSDEDMHTLN 295
Query: 297 EFGQKNK 303
+ +
Sbjct: 296 SIETRTR 302
>At5g62420 [R] KOG1577 Aldo/keto reductase family proteins
Length = 316
Score = 152 bits (383), Expect = 8e-37
Identities = 98/281 (34%), Positives = 149/281 (52%), Gaps = 19/281 (6%)
Query: 16 GNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEERV 75
G +P G+GT + T AV AIK GYRH DTA YG EE +G AL +
Sbjct: 11 GETIPLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAISYGT 70
Query: 76 VKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVDKIA 135
V+R+DL +TSK+W + +D +L ++L + +DY+D +L HWP+ + P + I
Sbjct: 71 VQRDDLFVTSKLWSSDHHDPISALIQTLKTMGLDYLDNYLVHWPIKLK----PGVSEPIP 126
Query: 136 KEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKECRTV 195
KE D+ L E ET++ +E+ R+IGVSNF + + +L
Sbjct: 127 KE--DEFEKDLGIE-----ETWQGMERCL---EMGLCRSIGVSNFSSKKIFDLLDFASVS 176
Query: 196 PACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNG-----APLLELPILKGLCEKYN 250
P+ NQVE+HP QR+L + C E+ I V+ YSPLGG G ++E PI+K + K+N
Sbjct: 177 PSVNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGGPGNCWGSTAVIEHPIIKSIALKHN 236
Query: 251 ASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEED 291
A+P + + + +G VI +S N R+ N + + +D
Sbjct: 237 ATPAQVALRWGMSKGASVIVKSFNGARMIENKRALEIKLDD 277
>CE01200 [R] KOG1577 Aldo/keto reductase family proteins
Length = 287
Score = 149 bits (375), Expect = 7e-36
Identities = 98/286 (34%), Positives = 152/286 (52%), Gaps = 31/286 (10%)
Query: 17 NKVPAFGLGT-AAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEERV 75
N +P G+GT Q E + +Q + A K GYR IDTA Y E +G L++L
Sbjct: 9 NNMPLIGIGTWQVQKEEIL--RQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANG 66
Query: 76 VKREDLHITSKVW--HTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVDK 133
+KRED+ ITSK+ + +S+ ESL+ LKV+Y+DL L HWP + K +P
Sbjct: 67 LKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENPAN--- 123
Query: 134 IAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKECR 193
K +E++ + ++ + ++R++GVSNF I +L+ + K+
Sbjct: 124 ----------------KKLRVESWNVMCEMMAEG---KLRSVGVSNFEICHLEELKKDSN 164
Query: 194 TVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGG--NGAPLLELPILKGLCEKYNA 251
VPA NQVE HPH Q +L ++C+E+ I AYS LG L E P++K L +KYN
Sbjct: 165 VVPAVNQVEYHPHFHQDDLVKYCNENNIHFQAYSSLGSPTYRKQLSEEPLIKELAQKYNV 224
Query: 252 SPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPL--SEEDVNKL 295
+L + QG V+PR+ N +A+N + L ++ED+++L
Sbjct: 225 EIPVLLLGFAYCQGISVLPRTTNPEHVATNFKVTKLAITQEDIDRL 270
>Hs17450865 [R] KOG1577 Aldo/keto reductase family proteins
Length = 310
Score = 145 bits (365), Expect = 1e-34
Identities = 101/323 (31%), Positives = 155/323 (47%), Gaps = 39/323 (12%)
Query: 14 NNGNKVPAFGLGT-AAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFE 72
N+G +P G GT A H ++ +A K AI G+RHID+A+ Y EE VG+A+ E
Sbjct: 13 NDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWEKIA 72
Query: 73 ERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHG 130
+ VKRE++ T K+W T + V +L SL +L DYVDLF+ H P + G
Sbjct: 73 DGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKP-----G 127
Query: 131 VDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLK 190
+ + K D G+ I ++ + ++ DK + N P
Sbjct: 128 KELLPK-----------DASGEIILETVELCDTWENQGDKHKLLELILNKP--------- 167
Query: 191 ECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP---------LLELPI 241
R P CNQVE HP+L Q +L EFC I++ AYS LG P LLE PI
Sbjct: 168 GLRYKPTCNQVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPI 227
Query: 242 LKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNEFG 299
LK + +K++ SP + Y L++G +V+ +S + RI N + L+ ED+ ++
Sbjct: 228 LKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMKAIDGLN 287
Query: 300 QKNKKRYINGAVSSVIPGFKEDF 322
+ + + A + F E++
Sbjct: 288 RNLRYDKLQFAANHPYFPFSEEY 310
>CE10936 [R] KOG1577 Aldo/keto reductase family proteins
Length = 283
Score = 144 bits (362), Expect = 2e-34
Identities = 96/284 (33%), Positives = 148/284 (51%), Gaps = 26/284 (9%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAV-KAAIKAGYRHIDTAWAYGVEEYVGEALQELFE 72
N G P GLGT ++ + + V AA+ AGYR DTA Y E+ +G+AL+ L
Sbjct: 6 NTGYDCPLIGLGT---YKIIGDQVLPVLDAALTAGYRLFDTAKVYNNEKEIGDALEILLP 62
Query: 73 ERVVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVD 132
+ +KRED+ IT+K+ +V K ++ESL+ LK Y+D++L H+P D
Sbjct: 63 KHNLKREDIFITTKMHPNTVENVKKLVDESLSLLKTSYIDMYLIHYP---------KSFD 113
Query: 133 KIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKEC 192
++P++ K I T+ + + KN ++R++GVS+F I +L+ +
Sbjct: 114 YGDQDPMN---------KTLRIATWNDLWEC---KNAGKIRSVGVSSFEIRHLEELKDLG 161
Query: 193 RTVP-ACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELPILKGLCEKYNA 251
+ P CNQVE HPH + EL +C I A+S L + LL I+ L EKY+
Sbjct: 162 KNFPPCCNQVEYHPHFTREELKNYCKSEGIFFQAFSSLARHNETLLSSEIITRLAEKYHV 221
Query: 252 SPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEEDVNKL 295
+L S+ Q +IP+S N R+A NL+ V L EE+V K+
Sbjct: 222 PKTTVLLSWATSQKVGIIPKSTNPERLAQNLKTVLLEEEEVKKI 265
>Hs17465400 [R] KOG1577 Aldo/keto reductase family proteins
Length = 384
Score = 141 bits (356), Expect = 1e-33
Identities = 109/357 (30%), Positives = 169/357 (46%), Gaps = 80/357 (22%)
Query: 18 KVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEERVVK 77
K+P GLGT + + K+AVK AI A YRHID A+ Y + VGEA+QE +E+ V
Sbjct: 12 KMPIVGLGT--WRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQEKIQEKAVM 69
Query: 78 REDLHITSKVW--HTMWND------VDKSLNESLARLKVDYVDLFLQHWP---------- 119
REDL I SKV H +W V K+ ++L LK+ Y+D++L HWP
Sbjct: 70 REDLFIVSKVHMAHLVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSLKKWY 129
Query: 120 --LCTQKVPDPHGVDKIAK--------------------EPVDDQGNPLYDEKGDWIETY 157
+ K DP + K P DD+GN + KG +++ +
Sbjct: 130 ADVVFSKHQDPETLLNRTKCPDADSSKLFILYLQTGDDFFPKDDKGN-MISGKGTFLDAW 188
Query: 158 KQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKE--CRTVPACN---------------- 199
+ +E++ ++ V+A+GVSNF ++R+L + + P N
Sbjct: 189 EAMEELV---DEGLVKALGVSNFNHFQIERLLNKPGLKYKPVTNQNSLGTMQNRAGFPRD 245
Query: 200 ------QVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP--------LLELPILKGL 245
QVE HP+L Q +L ++C I VTAYSPLG P LLE P +K +
Sbjct: 246 EDCLLLQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEI 305
Query: 246 CEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNEFGQ 300
K+ + +L +H+++ VIP+S+ I N++ LS+E++ + F +
Sbjct: 306 AAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNR 362
>7302301 [R] KOG1577 Aldo/keto reductase family proteins
Length = 311
Score = 139 bits (349), Expect = 7e-33
Identities = 96/320 (30%), Positives = 156/320 (48%), Gaps = 30/320 (9%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
NNG ++P GLGT E ++ + + A+ GYRH+DTA+ Y E VG+A+ E E
Sbjct: 11 NNGREMPTLGLGTWKSFE--SDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEKIAE 68
Query: 74 RVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDP--H 129
VV RE++ +T+K+ + V+++ SL+ L ++YVDL+L H P+ + D H
Sbjct: 69 GVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHNDSNVH 128
Query: 130 GVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVL 189
G ++ D+++T++++EK+ + R+IG+SNF +RVL
Sbjct: 129 GTLELTDV--------------DYLDTWREMEKLV---DLGLTRSIGLSNFNAAQTERVL 171
Query: 190 KECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPL-----GGNGAPLLELPILKG 244
CR P NQVE HP QR+L E H +++ AY PL P L +
Sbjct: 172 ANCRIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPLARPQPARQWPPFLYDEHAQN 231
Query: 245 LCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNEFGQKN 302
L +KY + I Y ++ G + +P+S N RI N LS +DV + ++
Sbjct: 232 LAKKYGRTTAQICLRYLVQLGVVPLPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQ 291
Query: 303 KKRYINGAVSSVIPGFKEDF 322
+ +G F ++F
Sbjct: 292 RTVPFSGMSGHKYYPFNDEF 311
>YHR104w [R] KOG1577 Aldo/keto reductase family proteins
Length = 327
Score = 135 bits (340), Expect = 8e-32
Identities = 92/311 (29%), Positives = 157/311 (49%), Gaps = 38/311 (12%)
Query: 12 TFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELF 71
T NNG K+P GLG ++V + + AIK GYR D A YG E+ VGE +++
Sbjct: 6 TLNNGLKMPLVGLGCWKIDKKVCANQ--IYEAIKLGYRLFDGACDYGNEKEVGEGIRKAI 63
Query: 72 EERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPH 129
E +V R+D+ + SK+W+ + V +L ++L+ + +DY+DL+ H+P+ + VP
Sbjct: 64 SEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEE 123
Query: 130 --------GVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFP 181
G D K + + P+ I+TY+ +E+ ++ +++IGVSNF
Sbjct: 124 KYPPGFYTGADDEKKGHITEAHVPI-------IDTYRALEECV---DEGLIKSIGVSNFQ 173
Query: 182 IEYLKRVLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNG-------- 233
++ +L+ CR P Q+E HP+L Q L EFC H I V AYS G
Sbjct: 174 GSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQL 233
Query: 234 ----APLLELPILKGLCEKY-NASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF---V 285
L E ++K + + + ++ + +L + ++G VIP+S R+ NLE
Sbjct: 234 AKTTPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKF 293
Query: 286 PLSEEDVNKLN 296
L+E+++ ++
Sbjct: 294 TLTEQELKDIS 304
>7294573 [R] KOG1577 Aldo/keto reductase family proteins
Length = 252
Score = 135 bits (339), Expect = 1e-31
Identities = 92/255 (36%), Positives = 136/255 (53%), Gaps = 22/255 (8%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
NNG ++P GLGT + + + + AV A++ GYRHIDTA+ Y E +G+ L +L +
Sbjct: 10 NNGYEMPILGLGT--YNLKKSRCEAAVCHALEMGYRHIDTAYLYRNEGIIGKVLAKLIGD 67
Query: 74 RVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGV 131
+ +KRE + + +K+W V + + L L VDY+DL+L H P+ GV
Sbjct: 68 QKLKREQVFLVTKLWDIYHEPKMVKYACDMQLKLLGVDYIDLYLMHSPV---------GV 118
Query: 132 DKIAKEPVDDQGN-PLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLK 190
D I+ E + N L D+++TY+ +E++ + VR++G+SNF LKR+L+
Sbjct: 119 DYISDEDLMPHENGQLRTNDVDYVDTYRSMEQLV---HLGLVRSLGLSNFNANQLKRLLE 175
Query: 191 ECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGA--PLLEL---PILKGL 245
C+ PA Q+E HP L Q L E C H I V AYSPLG A PL + L L
Sbjct: 176 NCQIKPANLQIECHPELVQVPLIELCKFHNITVVAYSPLGRPKACNPLPDYYTDSKLLAL 235
Query: 246 CEKYNASPNDILTSY 260
KY +P I+ Y
Sbjct: 236 AAKYGKTPAQIILRY 250
>CE06112 [R] KOG1577 Aldo/keto reductase family proteins
Length = 301
Score = 133 bits (334), Expect = 4e-31
Identities = 94/292 (32%), Positives = 153/292 (52%), Gaps = 28/292 (9%)
Query: 11 FTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQEL 70
F F++G ++P GLG + + E + +++AA+K+GYR DTA Y E ++G +L++
Sbjct: 12 FKFSDGYEMPKIGLGIS-RIETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKY 70
Query: 71 FEERVVKREDLHITSKVWHTMWNDVD---KSLNESLARLKVDYVDLFLQHWPLCTQKV-P 126
+ + RED+ IT+KV N V+ K L SLA L+ DYVDL L H+P
Sbjct: 71 LPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRDRDTGND 130
Query: 127 DPHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLK 186
D + ++K ++ V ++ +EK K RVR+IGVSN+ + +L
Sbjct: 131 DDYEINKSRRKIV-----------------WQTLEKA---KESGRVRSIGVSNYEVYHLV 170
Query: 187 RVLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELPILKGLC 246
+ + + P NQ E P+L + L +FC + I+V +YS L +L+ L LC
Sbjct: 171 EMFEYAKIRPVLNQYEYQPYLTRPTLKKFCDLNNIVVQSYSSLCWGDKEILQEKPLVDLC 230
Query: 247 EKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLE---FVPLSEEDVNKL 295
+KYN +P IL ++ T +IP+S +RI NL + L+E+++ L
Sbjct: 231 QKYNQTPQAILYAFAHCSNTSMIPKSATPSRIHDNLHNTIKIKLTEDELKSL 282
>CE10934 [R] KOG1577 Aldo/keto reductase family proteins
Length = 297
Score = 130 bits (327), Expect = 3e-30
Identities = 92/288 (31%), Positives = 148/288 (50%), Gaps = 30/288 (10%)
Query: 14 NNGNKVPAFGLGTAAQHERVAET-KQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFE 72
N+G +P G GT ++ E A+ AA+ AGYR DTA Y E+ +GEAL+ L
Sbjct: 16 NSGYNIPFVGFGT---YKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLP 72
Query: 73 ERVVKREDLHITSKVWHTMWNDVDKS---LNESLARLKVDYVDLFLQHWPLCTQKVPDPH 129
+ + R D+ +TSK + N + + ESL L+ DY+D++L H+P P+
Sbjct: 73 KHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYP-------KPN 125
Query: 130 GVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVL 189
D DD N Y + Y+ +E+ K +VR+IGVSN+ I +L+ +
Sbjct: 126 DSDN------DDVNNAEYRKIA-----YEVLEEA---KAAGKVRSIGVSNYEIVHLEELK 171
Query: 190 KECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELPILKGLCEKY 249
+ P NQ+E HPH + L ++C E I A+S L + L+E P++ L +K+
Sbjct: 172 TYAKVPPCANQLEYHPHFARIPLQKYCKEKNIFFQAFSSLARHEPKLIEDPVVVELAKKH 231
Query: 250 NASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKL 295
N S +L ++ LRQ ++P+S+ +RI N + + L+ ED+ L
Sbjct: 232 NTSVPLVLLAWALRQNVGIVPKSVTPSRIVENFKVIDIALTPEDIQSL 279
>At1g59960 [R] KOG1577 Aldo/keto reductase family proteins
Length = 326
Score = 129 bits (324), Expect = 6e-30
Identities = 92/291 (31%), Positives = 148/291 (50%), Gaps = 26/291 (8%)
Query: 17 NKVPAFGLGTAAQH-ERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEERV 75
+ +P G GTAA K+ V AIK GYRH DT+ Y EE +GEAL E +
Sbjct: 19 HSMPVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVSLGL 78
Query: 76 VK-REDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVD 132
V+ R + +T+K+W + V ++ SL LK+DY+DL++ HWP+ ++ P +
Sbjct: 79 VRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPVSSK--PGKY--- 133
Query: 133 KIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKEC 192
K P+D+ D + W E ++ +++ L K IGVSNF + L+ +L
Sbjct: 134 ---KFPIDEDDFMPMDFEVVWSEM-EECQRLGLAK------CIGVSNFSCKKLQHILSIA 183
Query: 193 RTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGA-----PLLELPILKGLCE 247
P+ NQVE+ P QR+L E C + I+VTAYS LG GA ++E +LK + E
Sbjct: 184 TIPPSVNQVEMSPIWQQRKLRELCRSNDIVVTAYSVLGSRGAFWGTPKIMESDVLKEIAE 243
Query: 248 KYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFV--PLSEEDVNKLN 296
+ + + QG ++ +S R+ NL+ L+E++ +++
Sbjct: 244 AKEKTVAQVSMRWAYEQGVSMVVKSFTKERLEENLKIFDWSLTEDETQRIS 294
>At1g59950 [R] KOG1577 Aldo/keto reductase family proteins
Length = 320
Score = 128 bits (322), Expect = 1e-29
Identities = 94/302 (31%), Positives = 151/302 (49%), Gaps = 24/302 (7%)
Query: 19 VPAFGLGTAAQHE-RVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEERVVK 77
+P LGTAA K+ V AIK GYRH DT+ Y EE +GEAL E +++
Sbjct: 15 MPVLALGTAASPPPEPIVLKRTVLEAIKLGYRHFDTSPRYQTEEPLGEALAEAVSLGLIQ 74
Query: 78 -REDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVDKI 134
R +L +TSK+W + V ++ SL LK+DY+DL+L HWP+ ++ P +
Sbjct: 75 SRSELFVTSKLWCADAHGGLVVPAIQRSLETLKLDYLDLYLIHWPVSSK--PGKY----- 127
Query: 135 AKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKECRT 194
K P+++ D + W E ++ +++ + K IGVSNF + L+ +L +
Sbjct: 128 -KFPIEEDDFLPMDYETVWSEM-EECQRLGVAK------CIGVSNFSCKKLQHILSIAKI 179
Query: 195 VPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGA-----PLLELPILKGLCEKY 249
P+ NQVE+ P QR+L E C I+VTAYS LG GA ++E +LK + E
Sbjct: 180 PPSVNQVEMSPVWQQRKLRELCKSKGIVVTAYSVLGSRGAFWGTHKIMESDVLKEIAEAK 239
Query: 250 NASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEFVPLSEEDVNKLNEFGQKNKKRYING 309
+ + + +G ++ +S R+ NL+ S + K + ++ R ++G
Sbjct: 240 GKTVAQVSMRWAYEEGVSMVVKSFRKDRLEENLKIFDWSLTEEEKQRISTEISQSRIVDG 299
Query: 310 AV 311
V
Sbjct: 300 EV 301
>SPAC19G12.09 [R] KOG1577 Aldo/keto reductase family proteins
Length = 284
Score = 126 bits (316), Expect = 5e-29
Identities = 101/301 (33%), Positives = 142/301 (46%), Gaps = 50/301 (16%)
Query: 19 VPAFGLGTAAQHERVAETKQ----AVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEER 74
VPA+G+GTA + E + +VK A+ AG+ HID A YG EE VG AL+E
Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALKEAN--- 68
Query: 75 VVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVDKI 134
V R L ITSKV H + N + ++LNESL +L DY+DL+L H P+
Sbjct: 69 -VPRSKLFITSKVMHNVDN-IPEALNESLRKLGTDYLDLYLLHSPI-------------- 112
Query: 135 AKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKECRT 194
P Y++K E +K +E V ++GVSNF I L+ +LK
Sbjct: 113 ----------PFYEKKIPISEGWKAMETAL---GTGLVHSVGVSNFRIPDLEELLKTSTI 159
Query: 195 VPACNQVELHPHL--PQRELCEFCSEHKILVTAYSPLGGNGAPLLE------LPILKGLC 246
P NQ+E HP + + L EFC I+V Y PL +PL+ K L
Sbjct: 160 TPRVNQIEFHPQVYKAAKPLVEFCQSKGIIVEGYGPL----SPLVRDAQGPVAEFTKSLE 215
Query: 247 EKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNEFGQKNKK 304
KY+ S IL + +G I I + R+ L F L + D+++L G ++ K
Sbjct: 216 SKYHVSDTQILLKWAYSKGVIPITTTSKIERMKECLNFDSFTLDKADIDELGTLGVQHHK 275
Query: 305 R 305
R
Sbjct: 276 R 276
>Hs22054710 [R] KOG1577 Aldo/keto reductase family proteins
Length = 418
Score = 125 bits (313), Expect = 1e-28
Identities = 90/270 (33%), Positives = 138/270 (50%), Gaps = 40/270 (14%)
Query: 14 NNGNKVPAFGLGT-AAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFE 72
N+G+ +P G GT A H ++ +A + AI AG+RHID A+ Y EE VG+A++E
Sbjct: 12 NDGHVMPMLGFGTYAPDHTPKSKAGEATEVAIDAGFRHIDAAFFYQNEEEVGKAIREKIA 71
Query: 73 ERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQKV----- 125
+ VKRED+ T+++W T + V +L SL +L++DYVDLF+ H PL + +
Sbjct: 72 DGPVKREDIFYTTELWTTFFRPELVRPALEGSLKKLQLDYVDLFIIHNPLAMKLLRRQKG 131
Query: 126 ---PDPHGVDKIAKE-----PVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGV 177
P + + + P D GN ++D D +T++ +EK K ++IGV
Sbjct: 132 NSHRKPSSLSSVFQPGEELLPKDASGNIIFDTV-DLRDTWEALEKC---KEAGLTKSIGV 187
Query: 178 SNFPIEYLKRVLKE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP 235
SNF + L+ +L + + P CN Q +L EFC I++ AY L + P
Sbjct: 188 SNFNHKLLELILNKPGLKYKPTCN---------QSKLLEFCKSKDIVLVAYRALASHRDP 238
Query: 236 ---------LLELPILKGLCEKYNASPNDI 256
LLE P LK + +KYN SP +
Sbjct: 239 NWMDPDSPYLLEEPTLKSIAKKYNRSPGQV 268
>SPAC2F3.05c [R] KOG1577 Aldo/keto reductase family proteins
Length = 275
Score = 123 bits (309), Expect = 3e-28
Identities = 96/297 (32%), Positives = 144/297 (48%), Gaps = 55/297 (18%)
Query: 10 YFTFNNGNKVPAFGLGTAAQHERVAETK--QAVKAAIKAGYRHIDTAWAYGVEEYVGEAL 67
+ NNG K P F G+ V TK +V AA++ GYRHID+A Y E G A+
Sbjct: 5 FVKLNNGLKCPQFAYGSYM----VNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAI 60
Query: 68 QELFEERVVKREDLHITSKVWHTMWNDVD------KSLNESLARLKVDYVDLFLQHWPLC 121
+ EE KRED+ TSK+ ND+ S++ S+ + Y+DLFL H P
Sbjct: 61 LKFMEETGTKREDIWFTSKL-----NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPY- 114
Query: 122 TQKVPDPHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFP 181
GD IE++K +EK + ++RAIGVSNF
Sbjct: 115 -----------------------------GDRIESWKALEK---GVEEGKLRAIGVSNFG 142
Query: 182 IEYLKRVL-KECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELP 240
+++ +L + +P NQ+ELHP Q+++ ++C I + AY+PL +G
Sbjct: 143 PHHIQELLDSHPKIIPCVNQIELHPFCSQQKVVDYCESKGIQLAAYAPL-VHGEKFGNKQ 201
Query: 241 ILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKL 295
+L + KYN S I+ Y L++G IV+P+S RI N + +S+ED+ KL
Sbjct: 202 LL-AIASKYNKSEAQIMIRYCLQRGFIVLPKSSTPRRIKENGDVFDFEISKEDMEKL 257
>CE24244 [R] KOG1577 Aldo/keto reductase family proteins
Length = 339
Score = 120 bits (300), Expect = 4e-27
Identities = 83/284 (29%), Positives = 147/284 (51%), Gaps = 24/284 (8%)
Query: 12 TFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELF 71
T N+G ++P G GT + +A + V+ A++AGYRHID+A ++ +E V +++
Sbjct: 8 TLNSGYEMPVIGYGTWQLPKNLAAER--VRDALEAGYRHIDSALSFKNQEEVAAGIKDWC 65
Query: 72 EERVVKREDLHITSKVWHTMW--NDVDKSLNESLARLKVDYVDLFLQHWPL--CTQKVPD 127
+ R V+RE+L ++SK+W+T N + ++E L + Y+DL + HWP + P
Sbjct: 66 KIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAEDEPPG 125
Query: 128 PHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKR 187
G+ P G Y + D++ET+K +E + ++R+IG++NF I +++
Sbjct: 126 ERGL-----WPRGANGKMRYSDV-DYLETWKALEDAH---RSGKIRSIGLANFNIGQVEQ 176
Query: 188 VLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP---------LLE 238
V + PA QVE++P L Q E+ +FC E I++TA+ G G+ LL
Sbjct: 177 VWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPGSALYRKHEDPNLLY 236
Query: 239 LPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNL 282
L+ + + + S +L + + T + +S S RI N+
Sbjct: 237 NETLQSIAKGHGKSVVQVLVRWAIDLRTTALVKSSESKRIRQNI 280
>CE15543 [R] KOG1577 Aldo/keto reductase family proteins
Length = 376
Score = 117 bits (294), Expect = 2e-26
Identities = 100/329 (30%), Positives = 150/329 (45%), Gaps = 50/329 (15%)
Query: 14 NNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEE 73
+N ++P GLGT H + + K GYR IDTA YGVE+ +G A++
Sbjct: 8 SNNVEMPLIGLGTT--HSGGYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAVKNCS-- 63
Query: 74 RVVKREDLHITSKVWHTMWND-VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVD 132
V RE++ +++K+W D V + S +L+ DY+D+++ H P ++PD
Sbjct: 64 --VPREEMFLSTKLWPVDCGDEVYNAFQTSCEKLQTDYLDMYMIHMP----QLPDWIVNQ 117
Query: 133 KIAKEPVDDQGNPLYDEK--GDWIETYK-----------------QIEKIYL-------- 165
K KE Q LY++ G + +K ++ K+ L
Sbjct: 118 KETKEKTWRQMELLYEDGKFGFCFKCFKLAFGEATSYIALKISCNELCKLNLKLPMSISR 177
Query: 166 DKNDK--------RVRAIGVSNFPIEYLKRVLKECRTVPACNQVELHPHLPQRELCEFCS 217
KN + VR+IGVSN+ IE L +L+ +P NQVELHP Q +L +C
Sbjct: 178 SKNPQTNFTIITEHVRSIGVSNYSIEDLDELLEFASILPHANQVELHPWFHQADLKNYCD 237
Query: 218 EHKILVTAYSPLGGNGAPLLELPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTR 277
E IL Y PL LE L + KY SP I + ++Q +P+S + R
Sbjct: 238 ELGILTMGYCPLA--KGKYLEDETLCKIASKYQKSPAQICLRWSIQQNVPTVPKSTDCRR 295
Query: 278 IASNLEF--VPLSEEDVNKLNEFGQKNKK 304
+ N LS ED+N LN F +N+K
Sbjct: 296 LKENTNVFDFELSAEDMNTLNSFSSQNRK 324
>CE06751 [R] KOG1577 Aldo/keto reductase family proteins
Length = 287
Score = 116 bits (290), Expect = 5e-26
Identities = 83/296 (28%), Positives = 148/296 (49%), Gaps = 37/296 (12%)
Query: 11 FTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQEL 70
F NG ++P LGT + + AV A+K GYR DTA Y E+ +G AL+ L
Sbjct: 2 FKLKNGQEIPKLALGT--YEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTL 59
Query: 71 FEERVVKREDLHITSKVWHTMWND----VDKSLNESLARLKVDYVDLFLQHWPLCTQKVP 126
+ ED+++TSKV+ + + K +NESL L Y+DL L H+P
Sbjct: 60 LPRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYP------- 112
Query: 127 DPHGVDKIAKEPVD----DQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPI 182
P+D ++ N +Y K WI +EK++ + ++R+IGVSN+
Sbjct: 113 ----------RPLDTEDLNENNKMY-RKDTWIA----LEKLHAEG---KIRSIGVSNYEP 154
Query: 183 EYLKRVLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELPIL 242
+++ + P NQ+E HPH ++ L +C++++IL A+SPLG LL +
Sbjct: 155 HHIEEMRSYITIEPQVNQIEYHPHFQRKVLRAYCNKNEILFQAFSPLGRGNKTLLGDSTM 214
Query: 243 KGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLE--FVPLSEEDVNKLN 296
+ + + + +++ ++ ++ V+ +S+ +R+A N + LS+++ K+N
Sbjct: 215 ERIALCHKTTVANVILAWIMKGKYGVVAKSVTPSRVAENYTSLSLELSDDEFEKIN 270
>YDL124w [R] KOG1577 Aldo/keto reductase family proteins
Length = 312
Score = 114 bits (286), Expect = 1e-25
Identities = 102/318 (32%), Positives = 149/318 (46%), Gaps = 56/318 (17%)
Query: 10 YFTFNNGNKVPAFGL-GTAAQHERVAET---------KQAVKAAIKAGYRHIDTAWAYGV 59
+FT NNGNK+PA + GT + + ET +Q V A G HID A Y
Sbjct: 7 FFTLNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRT 66
Query: 60 EEYVGEALQELFEERVVKREDLHITSKVWHT--MWNDVDKSLNESLARLKVDYVDLFLQH 117
VG+AL L E+ R + +T K M + L+ +L ++ DYVDL+L H
Sbjct: 67 YPEVGKALS-LTEK---PRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLH 122
Query: 118 WPLCTQKVPDPHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGV 177
P +++V N L E E +K +E++Y + + IGV
Sbjct: 123 SPFVSKEV------------------NGLSLE-----EAWKDMEQLY---KSGKAKNIGV 156
Query: 178 SNFPIEYLKRVLKECRTVPACNQVELHPHLPQRE--LCEFCSEHKILVTAYSPLG----- 230
SNF +E L+R+LK P NQ+E P L + + +FC EH ILV AYSPLG
Sbjct: 157 SNFAVEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKK 216
Query: 231 ---GNGAPLLELPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRI--ASNLEFV 285
+ P E +K L EKY S I+ + ++G + + S RI A NL
Sbjct: 217 TAQDDSQPFFE--YVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQNLFSF 274
Query: 286 PLSEEDVNKLNEFGQKNK 303
L+ E+V+K+ E G +++
Sbjct: 275 DLTAEEVDKITELGLEHE 292
>Hs20470761 [R] KOG1577 Aldo/keto reductase family proteins
Length = 222
Score = 112 bits (279), Expect = 1e-24
Identities = 81/251 (32%), Positives = 123/251 (48%), Gaps = 48/251 (19%)
Query: 9 IYFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQ 68
I+ N K+P GLGT + + K+ VK AI AGYRHID A+ Y E VGEA+Q
Sbjct: 3 IFVELNTKAKMPIVGLGT--WKSPLGKVKEVVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60
Query: 69 ELFEERVVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDP 128
E +E+ VKREDL I +K+W T + + +
Sbjct: 61 EKIQEKAVKREDLFIINKLWPTFFE-----------------------------RPLGYK 91
Query: 129 HGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRV 188
G D K DD+GN + K +++ ++ +E++ ++ V+A+GVSNF ++R+
Sbjct: 92 SGDDFFRK---DDKGN-MIGGKAMFLDAWEAMEELV---DEGLVKALGVSNFNHFQIERL 144
Query: 189 LKE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGG--------NGAPLLE 238
L + + P NQVE HP+L Q +L ++C I + AYSPLG LLE
Sbjct: 145 LNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITIMAYSPLGSPDRLWAKPEDPSLLE 204
Query: 239 LPILKGLCEKY 249
P +K + ++
Sbjct: 205 DPKIKEIAARH 215
>SPAP32A8.02 [R] KOG1577 Aldo/keto reductase family proteins
Length = 283
Score = 107 bits (267), Expect = 2e-23
Identities = 86/293 (29%), Positives = 146/293 (49%), Gaps = 39/293 (13%)
Query: 12 TFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELF 71
T NG +P G G A + E V A+ +GYRHIDTA YG E+ G+A+ +
Sbjct: 12 TLTNGMVIPRIGFG--AFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWC 69
Query: 72 EERVVKREDLHITSKVWHTM-WNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHG 130
E+ VKR D+ +TSK+ + + ++ SL L Y+DLFL + P G
Sbjct: 70 EKNNVKRTDIFLTSKLANCSDYYSTRAAIRSSLHHLGT-YIDLFL---------IQSPAG 119
Query: 131 VDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVL- 189
K I ++K +E+ ++D D +R++GVSN+ +++L+ +
Sbjct: 120 GKKSR------------------IASWKAMEE-FVDSGD--IRSVGVSNYGVKHLQELYA 158
Query: 190 KECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELPILKGLCEKY 249
+ P NQ+ELHP L Q ++ ++C H I + AYSPL +G L + ++ + +K
Sbjct: 159 SNPKFYPCVNQIELHPFLSQDDIVKYCQSHDIAIEAYSPL-THGIRLNDEKLVP-IAKKL 216
Query: 250 NASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLNEFGQ 300
N S +L + L++G I I +S + S+L+ + ++ V +L+ F +
Sbjct: 217 NISVAQLLIRWSLQKGYIPIIKSTKKEHMLSDLDVFNFTIPDDVVQELSSFDE 269
>YJR096w [R] KOG1577 Aldo/keto reductase family proteins
Length = 282
Score = 103 bits (257), Expect = 3e-22
Identities = 73/280 (26%), Positives = 144/280 (51%), Gaps = 41/280 (14%)
Query: 10 YFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQE 69
++ +NG K+P+ LGT ++T + V +K GYRH DTA YG E+ VG+ + +
Sbjct: 5 FYKLSNGFKIPSIALGTYDIPR--SQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIK 62
Query: 70 LFEERVV--KREDLHITSKVWHTM--WNDVDKSLNESLARLK-VDYVDLFLQHWPLCTQK 124
E KRE++ T+K+W++ + ++ + L + + Y+DL L H PL
Sbjct: 63 WLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL---- 118
Query: 125 VPDPHGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEY 184
+G+ L +ET++ +++ ++ V++IGVSN+ ++
Sbjct: 119 -----------------EGSKLR------LETWRAMQEAV---DEGLVKSIGVSNYGKKH 152
Query: 185 LKRVLK--ECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAPLLELPIL 242
+ +L E + P NQ+E+ P + ++EL ++C ++V A++PL +G + +L
Sbjct: 153 IDELLNWPELKHKPVVNQIEISPWIMRQELADYCKSKGLVVEAFAPL-CHGYKMTNPDLL 211
Query: 243 KGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNL 282
K +C++ + +P +L + L+ G + +P++ R+ NL
Sbjct: 212 K-VCKEVDRNPGQVLIRWSLQHGYLPLPKTKTVKRLEGNL 250
>Hs20545142 [R] KOG1577 Aldo/keto reductase family proteins
Length = 280
Score = 103 bits (256), Expect = 5e-22
Identities = 86/304 (28%), Positives = 141/304 (46%), Gaps = 70/304 (23%)
Query: 10 YFTFNNGNKVPAFGLGT-AAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQ 68
+ NNG K+P GLGT + RV E AV AI GY HID A E VG A+Q
Sbjct: 4 HLVLNNGTKMPILGLGTWKSPPGRVTE---AVNVAINVGYCHIDCAHH---ENEVGVAIQ 57
Query: 69 ELFEERVVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDP 128
E E+VVKRE+L I + W ++
Sbjct: 58 EKLREQVVKREELFIVT--WEGIF------------------------------------ 79
Query: 129 HGVDKIAKEPVDDQGNPLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRV 188
P+++ GN + + + ++T+ +E++ ++ ++AIG+SNF ++R+
Sbjct: 80 ---------PLNELGNVVPSDT-NILDTWAAMEELV---DEWLMKAIGISNFNHLQVERL 126
Query: 189 LKE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP--------LLE 238
L + + P NQ+E HP+L Q +L ++C I+VTAYSP+G P LL
Sbjct: 127 LNKPGLKYKPVVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPVGTPSRPWVNPEDPSLLR 186
Query: 239 LPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLN 296
P +K + K+N + +L + +++ VIP+S+ IA N + L+ +D+ L
Sbjct: 187 DPRIKAIAAKHNKTTAQVLIRFPMQRNLGVIPKSVTPELIADNFKVFDFELNSQDMTALL 246
Query: 297 EFGQ 300
+ +
Sbjct: 247 SYNR 250
>Hs20537171 [R] KOG1577 Aldo/keto reductase family proteins
Length = 241
Score = 89.0 bits (219), Expect = 9e-18
Identities = 84/304 (27%), Positives = 129/304 (41%), Gaps = 86/304 (28%)
Query: 10 YFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQE 69
+ NNG K+P GLGT + + +AVK AI GY HID A Y E VG A++E
Sbjct: 4 HIVLNNGTKMPILGLGT--WNSPPGQVTEAVKVAINVGYCHIDCAHVYQNENDVGVAIRE 61
Query: 70 LFEERVVKREDLHITSKVWHTMWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPH 129
E+VVK E+L ITSK LC
Sbjct: 62 KLREQVVKCEELFITSK---------------------------------LCF------- 81
Query: 130 GVDKIAKE--PVDDQGN-PLYDEKGDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLK 186
K KE P+D+ GN + + ++T+ +E++ ++ V+AIG+SNF
Sbjct: 82 ---KPGKEFFPLDEPGNGNVVPSNSNILDTWAGMEELV---DEGLVKAIGISNF------ 129
Query: 187 RVLKECRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPLGGNGAP--------LLE 238
HL Q +L ++C I+VTAYS P LLE
Sbjct: 130 ------------------NHL-QEKLIQYCQSKGIMVTAYSSFSSPDRPWAKPEDPSLLE 170
Query: 239 LPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLEF--VPLSEEDVNKLN 296
P +K + K+N + +L + +++ +VIP+S+ IA N + L+ +D+ L
Sbjct: 171 DPRIKAITAKHNKTTAQVLIWFPMQRNLVVIPKSVTPECIAENFKVFNFELNSQDMTTLF 230
Query: 297 EFGQ 300
+ +
Sbjct: 231 SYNR 234
>Hs16156291 [R] KOG1577 Aldo/keto reductase family proteins
Length = 130
Score = 81.6 bits (200), Expect = 1e-15
Identities = 43/113 (38%), Positives = 71/113 (62%), Gaps = 3/113 (2%)
Query: 14 NNGNKVPAFGLGTA-AQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFE 72
N+G +P G GT+ A+ ++ ++AV+ AI GYRHID+A+ + EE +G+A+++
Sbjct: 12 NDGKFMPILGFGTSVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIRKKIA 71
Query: 73 ERVVKREDLHITSKVWHTMWND--VDKSLNESLARLKVDYVDLFLQHWPLCTQ 123
VKR+D+ T+KVW T V + L SL +L++ Y+DL+L H+P+ Q
Sbjct: 72 NGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQ 124
>SPBC28F2.05c [R] KOG1577 Aldo/keto reductase family proteins
Length = 276
Score = 79.3 bits (194), Expect = 7e-15
Identities = 69/253 (27%), Positives = 117/253 (45%), Gaps = 44/253 (17%)
Query: 38 QAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEERV-VKREDLHITSKV------WHT 90
Q V A+ G R ID+A Y E+ +A+Q+ + V +KRED+ + +K+ +
Sbjct: 28 QQVIEALSLGIRVIDSAITYRNEKECEQAIQDFCHQNVNIKREDITLITKIPDSLQGFER 87
Query: 91 MWNDVDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVDKIAKEPVDDQGNPLYDEK 150
W V++SL + R K+D V + WP+
Sbjct: 88 TWKAVEQSLRRT-GRPKLDVVLIHSPKWPVRR---------------------------- 118
Query: 151 GDWIETYKQIEKIYLDKNDKRVRAIGVSNFPIEYLKRVLKECRTVPACNQVELHPHLPQR 210
IE+++ + + + + R+ IGVSN+ I +L+ ++ +PA NQVE +
Sbjct: 119 ---IESWRALLQ---HQKEGRINKIGVSNYNIHHLEEIISLGLPLPAINQVEFSAFNNRP 172
Query: 211 ELCEFCSEHKILVTAYSPLGGNGAPLLELPILKGLCEKYNASPNDILTSYHLRQGTIVIP 270
+C H ILV A+SPL G L ++ +L L KYN +P +IL Y L++G I
Sbjct: 173 TFLSYCFNHGILVQAFSPL-TRGYRLSDIRLL-DLSLKYNKTPANILLRYCLQKGVSPIF 230
Query: 271 RSLNSTRIASNLE 283
++ + I N++
Sbjct: 231 KASSFVHIHENVK 243
>CE06775 [R] KOG1577 Aldo/keto reductase family proteins
Length = 134
Score = 71.2 bits (173), Expect = 2e-12
Identities = 38/78 (48%), Positives = 50/78 (63%), Gaps = 2/78 (2%)
Query: 10 YFTFNNGNKVPAFGLGTAAQHERVAETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQE 69
+ T +N + +PA GLGT + AVKAA+K GY IDTA Y EE++G A++E
Sbjct: 47 HLTLSNAHSMPAVGLGT--WQSNAEDVISAVKAAVKNGYSLIDTASGYNNEEFIGTAIKE 104
Query: 70 LFEERVVKREDLHITSKV 87
+ E VVKREDL IT+KV
Sbjct: 105 VIAEGVVKREDLFITTKV 122
>Hs22060498 [R] KOG1577 Aldo/keto reductase family proteins
Length = 594
Score = 53.1 bits (126), Expect = 5e-07
Identities = 37/136 (27%), Positives = 70/136 (51%), Gaps = 10/136 (7%)
Query: 172 VRAIGVSNFPIEYLKRVLKE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPL 229
V+AIG+S F +++R+L + + P ++E +L Q++L ++C I+VTAYSPL
Sbjct: 10 VKAIGISKFNYSHVRRILNKRGLKYQPMVKEIEFCTYLTQKKLIQYCQSKGIMVTAYSPL 69
Query: 230 GGNGAP---LLELPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLE--F 284
P L + +L+ K ++ T+ ++ +V P+S+ IA N + +
Sbjct: 70 DCLDRPWAKLKDSSVLEDARSKVITVKHNKTTA---QRNLVVNPKSVTQKCIAENFKAFY 126
Query: 285 VPLSEEDVNKLNEFGQ 300
LS +D+ L + +
Sbjct: 127 FELSSKDMTTLPSYNR 142
>Hs22058392 [R] KOG1577 Aldo/keto reductase family proteins
Length = 156
Score = 53.1 bits (126), Expect = 5e-07
Identities = 37/136 (27%), Positives = 70/136 (51%), Gaps = 10/136 (7%)
Query: 172 VRAIGVSNFPIEYLKRVLKE--CRTVPACNQVELHPHLPQRELCEFCSEHKILVTAYSPL 229
V+AIG+S F +++R+L + + P ++E +L Q++L ++C I+VTAYSPL
Sbjct: 10 VKAIGISKFNYSHVRRILNKRGLKYQPMVKEIEFCTYLTQKKLIQYCQSKGIMVTAYSPL 69
Query: 230 GGNGAP---LLELPILKGLCEKYNASPNDILTSYHLRQGTIVIPRSLNSTRIASNLE--F 284
P L + +L+ K ++ T+ ++ +V P+S+ IA N + +
Sbjct: 70 DCLDRPWAKLKDSSVLEDARSKVITVKHNKTTA---QRNLVVNPKSVTQKCIAENFKAFY 126
Query: 285 VPLSEEDVNKLNEFGQ 300
LS +D+ L + +
Sbjct: 127 FELSSKDMTTLPSYNR 142
>Hs22048214 [R] KOG1577 Aldo/keto reductase family proteins
Length = 159
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/112 (31%), Positives = 54/112 (47%), Gaps = 19/112 (16%)
Query: 35 ETKQAVKAAIKAGYRHIDTAWAYGVEEYVGEALQELFEERVVKREDLHITSKVWHTMWND 94
+ +AVK AI Y + E +G A+QE ++VKRE+L I SK+W T
Sbjct: 6 QVTKAVKVAIDIRYEN---------ENEIGVAIQEKLRGQMVKREELFIISKLWCTYHGK 56
Query: 95 --VDKSLNESLARLKVDYVDLFLQHWPLCTQKVPDPHGVDKIAKEPVDDQGN 144
V + + L+ LK Y+D +L HWP ++ + P+D+ GN
Sbjct: 57 GLVKGACQKMLSDLKQGYLDYYLVHWPASFKRGKESF--------PLDESGN 100
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,417,771
Number of Sequences: 60738
Number of extensions: 977151
Number of successful extensions: 2591
Number of sequences better than 1.0e-05: 63
Number of HSP's better than 0.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2333
Number of HSP's gapped (non-prelim): 73
length of query: 330
length of database: 30,389,216
effective HSP length: 107
effective length of query: 223
effective length of database: 23,890,250
effective search space: 5327525750
effective search space used: 5327525750
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)