ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0779 check: MH T KOG0661 Signal transduction mechanisms MAPK related serine/threonine protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0779 264329 266593 755
(755 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 417 e-116
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 214 3e-55
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 182 2e-45
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 181 4e-45
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 180 6e-45
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 176 9e-44
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 173 1e-42
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 172 1e-42
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 171 4e-42
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 167 7e-41
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 158 3e-38
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 152 2e-36
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 125 2e-28
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 120 8e-27
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 119 1e-26
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 119 2e-26
CE29318 [T] KOG0660 Mitogen-activated protein kinase 118 4e-26
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 117 5e-26
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 116 1e-25
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 115 2e-25
YHR030c [T] KOG0660 Mitogen-activated protein kinase 115 2e-25
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 115 3e-25
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 115 3e-25
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 114 6e-25
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 114 6e-25
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 114 7e-25
YGR040w [T] KOG0660 Mitogen-activated protein kinase 112 2e-24
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 112 2e-24
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 110 6e-24
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 110 6e-24
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 110 6e-24
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 110 6e-24
YBL016w [T] KOG0660 Mitogen-activated protein kinase 110 8e-24
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 110 8e-24
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 110 8e-24
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 110 8e-24
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 110 1e-23
SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 110 1e-23
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 110 1e-23
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 110 1e-23
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 110 1e-23
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 110 1e-23
CE24971 [T] KOG0660 Mitogen-activated protein kinase 109 2e-23
CE01583 [T] KOG0660 Mitogen-activated protein kinase 109 2e-23
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 109 2e-23
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 108 2e-23
CE29020 [T] KOG0660 Mitogen-activated protein kinase 108 2e-23
SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylatio... 108 3e-23
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 108 4e-23
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 108 4e-23
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 107 5e-23
Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 107 7e-23
Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 107 7e-23
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 7e-23
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 7e-23
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 7e-23
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 7e-23
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 7e-23
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 7e-23
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 7e-23
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 7e-23
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 7e-23
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 107 7e-23
YPR054w [T] KOG0660 Mitogen-activated protein kinase 106 1e-22
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 106 1e-22
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 106 2e-22
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 106 2e-22
Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 105 3e-22
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 105 3e-22
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 105 3e-22
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 105 3e-22
YMR139w [G] KOG0658 Glycogen synthase kinase-3 105 3e-22
YLR113w [T] KOG0660 Mitogen-activated protein kinase 105 3e-22
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 105 3e-22
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 105 3e-22
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 105 3e-22
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 105 3e-22
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 104 4e-22
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 104 6e-22
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 104 6e-22
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 104 6e-22
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 103 7e-22
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 103 7e-22
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 103 7e-22
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 103 1e-21
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 103 1e-21
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 103 1e-21
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 103 1e-21
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 103 1e-21
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 103 1e-21
CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 102 2e-21
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 102 2e-21
7290342 [G] KOG0658 Glycogen synthase kinase-3 102 2e-21
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 102 2e-21
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 102 3e-21
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 3e-21
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 102 3e-21
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 101 4e-21
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 101 5e-21
CE21401 [G] KOG0658 Glycogen synthase kinase-3 101 5e-21
7291043 [T] KOG0660 Mitogen-activated protein kinase 101 5e-21
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 100 6e-21
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 6e-21
ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 100 6e-21
CE06686 [T] KOG0660 Mitogen-activated protein kinase 100 6e-21
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 6e-21
7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 100 6e-21
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 8e-21
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 8e-21
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 100 8e-21
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 100 1e-20
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 100 1e-20
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 100 1e-20
7301110 [T] KOG0660 Mitogen-activated protein kinase 100 1e-20
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 1e-20
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 99 2e-20
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 99 2e-20
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 99 2e-20
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 99 2e-20
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 99 2e-20
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 99 2e-20
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 99 2e-20
7298087 [T] KOG0660 Mitogen-activated protein kinase 99 2e-20
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 99 3e-20
At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 99 3e-20
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 99 3e-20
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 98 5e-20
At2g42880 [T] KOG0660 Mitogen-activated protein kinase 98 5e-20
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 97 7e-20
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 97 7e-20
7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 97 7e-20
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 97 9e-20
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 97 1e-19
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 97 1e-19
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 97 1e-19
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 96 2e-19
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 96 2e-19
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 96 2e-19
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 2e-19
YKL139w [D] KOG0600 Cdc2-related protein kinase 96 3e-19
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 3e-19
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 96 3e-19
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 96 3e-19
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 3e-19
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 96 3e-19
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 96 3e-19
CE26422 [D] KOG0600 Cdc2-related protein kinase 96 3e-19
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 96 3e-19
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 95 3e-19
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 95 3e-19
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 95 3e-19
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 95 3e-19
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 95 5e-19
Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 95 5e-19
CE06762 [T] KOG0660 Mitogen-activated protein kinase 95 5e-19
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 95 5e-19
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 95 5e-19
YKL161c [T] KOG0660 Mitogen-activated protein kinase 94 6e-19
YDL079c [G] KOG0658 Glycogen synthase kinase-3 94 8e-19
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 94 8e-19
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 94 8e-19
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 94 8e-19
Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 94 1e-18
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 94 1e-18
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 94 1e-18
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 93 1e-18
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 93 1e-18
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 93 1e-18
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 93 2e-18
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 93 2e-18
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 93 2e-18
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 93 2e-18
YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 92 2e-18
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 92 2e-18
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 92 2e-18
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 92 2e-18
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 92 3e-18
At1g53510 [T] KOG0660 Mitogen-activated protein kinase 92 3e-18
Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 92 4e-18
CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 92 4e-18
At4g22940 [D] KOG0600 Cdc2-related protein kinase 91 5e-18
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 91 5e-18
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 91 5e-18
YNL307c [G] KOG0658 Glycogen synthase kinase-3 91 7e-18
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 91 7e-18
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 91 7e-18
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 91 7e-18
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 91 9e-18
At1g53050 [D] KOG0600 Cdc2-related protein kinase 91 9e-18
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 91 9e-18
YOL128c [G] KOG0658 Glycogen synthase kinase-3 90 1e-17
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 90 1e-17
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 90 1e-17
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 90 1e-17
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 89 2e-17
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 89 2e-17
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 89 2e-17
At1g18670 [D] KOG0600 Cdc2-related protein kinase 89 2e-17
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 89 2e-17
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 89 3e-17
CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 88 4e-17
CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 88 4e-17
CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 88 4e-17
Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 88 6e-17
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 87 7e-17
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 7e-17
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 7e-17
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 87 9e-17
Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 87 9e-17
Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 87 9e-17
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 87 9e-17
Hs10190706 [T] KOG0671 LAMMER dual specificity kinases 87 9e-17
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 9e-17
CE17062 [T] KOG0660 Mitogen-activated protein kinase 87 1e-16
At5g64960 [D] KOG0600 Cdc2-related protein kinase 87 1e-16
At1g74330 [D] KOG0600 Cdc2-related protein kinase 87 1e-16
At1g54610 [D] KOG0600 Cdc2-related protein kinase 87 1e-16
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 87 1e-16
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 86 2e-16
7301719 [T] KOG0671 LAMMER dual specificity kinases 86 2e-16
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 86 2e-16
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 86 2e-16
At1g33770 [D] KOG0600 Cdc2-related protein kinase 86 2e-16
At5g10270 [D] KOG0600 Cdc2-related protein kinase 86 3e-16
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 86 3e-16
7296451 [D] KOG0600 Cdc2-related protein kinase 85 5e-16
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 85 5e-16
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 84 6e-16
Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 84 8e-16
Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases 84 8e-16
YPR161c [D] KOG0600 Cdc2-related protein kinase 84 1e-15
Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 84 1e-15
Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 84 1e-15
Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 84 1e-15
Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 84 1e-15
Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 84 1e-15
CE20405 [G] KOG0658 Glycogen synthase kinase-3 84 1e-15
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 83 1e-15
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 83 2e-15
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 83 2e-15
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 83 2e-15
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 83 2e-15
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 82 2e-15
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 82 2e-15
Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK) 82 3e-15
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 82 3e-15
At5g44290 [D] KOG0600 Cdc2-related protein kinase 82 3e-15
At5g39420 [D] KOG0600 Cdc2-related protein kinase 82 3e-15
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 82 3e-15
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 82 4e-15
CE08727 [G] KOG0658 Glycogen synthase kinase-3 82 4e-15
At5g50860 [D] KOG0600 Cdc2-related protein kinase 81 5e-15
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 81 7e-15
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 81 7e-15
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 81 7e-15
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 81 7e-15
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 80 9e-15
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 80 9e-15
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 80 9e-15
At4g10010 [D] KOG0600 Cdc2-related protein kinase 80 1e-14
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 80 2e-14
Hs16306492 [R] KOG0594 Protein kinase PCTAIRE and related kinases 80 2e-14
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 80 2e-14
At3g17750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 80 2e-14
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 79 2e-14
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 79 3e-14
At4g32660 [T] KOG0671 LAMMER dual specificity kinases 79 3e-14
At1g57700 [D] KOG0600 Cdc2-related protein kinase 77 7e-14
At1g73460 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 77 1e-13
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 77 1e-13
SPCC777.14 [A] KOG0670 U4/U6-associated splicing factor PRP4 75 4e-13
Hs17999535 [A] KOG0670 U4/U6-associated splicing factor PRP4 75 4e-13
At1g03740 [D] KOG0600 Cdc2-related protein kinase 75 4e-13
At3g05050 [D] KOG0600 Cdc2-related protein kinase 75 5e-13
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 74 8e-13
At4g28980 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 8e-13
At1g09600 [D] KOG0600 Cdc2-related protein kinase 74 8e-13
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 73 1e-12
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 73 1e-12
At3g25840 [A] KOG0670 U4/U6-associated splicing factor PRP4 73 1e-12
CE19219 [T] KOG0665 Jun-N-terminal kinase (JNK) 73 2e-12
At1g71530 [D] KOG0600 Cdc2-related protein kinase 72 3e-12
At2g23080 [TDK] KOG0668 Casein kinase II alpha subunit 71 5e-12
CE05377 [G] KOG0658 Glycogen synthase kinase-3 70 9e-12
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 70 1e-11
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 2e-11
At3g53640 [A] KOG0670 U4/U6-associated splicing factor PRP4 70 2e-11
CE17321 [TDK] KOG0668 Casein kinase II alpha subunit 69 3e-11
CE05549 [T] KOG0671 LAMMER dual specificity kinases 69 3e-11
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 69 3e-11
7291932 [A] KOG0670 U4/U6-associated splicing factor PRP4 69 3e-11
Hs4503095 [TDK] KOG0668 Casein kinase II alpha subunit 68 5e-11
At1g73450 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 68 6e-11
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 68 6e-11
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 67 8e-11
CE01612 [G] KOG0658 Glycogen synthase kinase-3 67 1e-10
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 67 1e-10
CE05686 [A] KOG0670 U4/U6-associated splicing factor PRP4 66 2e-10
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 66 2e-10
CE27220 [T] KOG0660 Mitogen-activated protein kinase 65 3e-10
CE19749 [T] KOG0665 Jun-N-terminal kinase (JNK) 65 3e-10
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 4e-10
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 4e-10
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 4e-10
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 4e-10
Hs4503097 [TDK] KOG0668 Casein kinase II alpha subunit 65 5e-10
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 65 5e-10
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 65 5e-10
At2g41920 [T] KOG0198 MEKK and related serine/threonine protein ... 64 1e-09
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 63 1e-09
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 63 1e-09
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 63 1e-09
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 63 1e-09
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 63 1e-09
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 63 1e-09
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 63 1e-09
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 63 2e-09
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 63 2e-09
7298004 [G] KOG0658 Glycogen synthase kinase-3 62 2e-09
CE19302_1 [G] KOG0658 Glycogen synthase kinase-3 62 2e-09
CE26621 [T] KOG0671 LAMMER dual specificity kinases 62 3e-09
At3g50000 [TDK] KOG0668 Casein kinase II alpha subunit 62 3e-09
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 62 4e-09
YAR018c [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 61 7e-09
At1g13350 [A] KOG0670 U4/U6-associated splicing factor PRP4 61 7e-09
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 60 9e-09
Hs4507221 [T] KOG1290 Serine/threonine protein kinase 60 1e-08
CE09532 [G] KOG0658 Glycogen synthase kinase-3 60 1e-08
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 60 2e-08
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 59 2e-08
Hs7106269 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 59 2e-08
At5g27790 [T] KOG0198 MEKK and related serine/threonine protein ... 59 2e-08
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 59 3e-08
At5g67380 [TDK] KOG0668 Casein kinase II alpha subunit 59 3e-08
At1g54510 [R] KOG0589 Serine/threonine protein kinase 59 3e-08
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 59 4e-08
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 59 4e-08
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 4e-08
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 58 5e-08
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 58 6e-08
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 58 6e-08
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 58 6e-08
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 58 6e-08
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 57 8e-08
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 57 8e-08
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 57 8e-08
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 57 8e-08
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 57 1e-07
CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 57 1e-07
At4g38470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 57 1e-07
At4g35500 [T] KOG1290 Serine/threonine protein kinase 57 1e-07
YKL101w [D] KOG0588 Serine/threonine protein kinase 57 1e-07
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 57 1e-07
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 57 1e-07
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 57 1e-07
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 57 1e-07
YMR216c [T] KOG1290 Serine/threonine protein kinase 56 2e-07
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 56 2e-07
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 56 2e-07
Hs22066955 [T] KOG0660 Mitogen-activated protein kinase 56 2e-07
Hs20468251 [R] KOG0667 Dual-specificity tyrosine-phosphorylation... 56 2e-07
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 56 2e-07
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 56 2e-07
At2g41910 [T] KOG0198 MEKK and related serine/threonine protein ... 56 2e-07
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 55 4e-07
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 55 5e-07
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 55 5e-07
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 55 5e-07
7297611 [T] KOG0614 cGMP-dependent protein kinase 55 5e-07
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 54 7e-07
CE20458 [T] KOG1290 Serine/threonine protein kinase 54 7e-07
CE20457 [T] KOG1290 Serine/threonine protein kinase 54 7e-07
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 54 7e-07
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 54 7e-07
CE02949 [T] KOG1290 Serine/threonine protein kinase 54 7e-07
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 54 7e-07
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 54 9e-07
CE24993 [D] KOG0669 Cyclin T-dependent kinase CDK9 54 9e-07
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 54 9e-07
CE05866 [G] KOG0658 Glycogen synthase kinase-3 54 9e-07
At2g17530 [T] KOG1290 Serine/threonine protein kinase 54 9e-07
7303211 [T] KOG4717 Serine/threonine protein kinase 54 9e-07
7296166 [T] KOG0614 cGMP-dependent protein kinase 54 9e-07
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 54 1e-06
Hs7657629 [T] KOG1290 Serine/threonine protein kinase 54 1e-06
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 54 1e-06
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 54 1e-06
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 54 1e-06
YLL019c [T] KOG0671 LAMMER dual specificity kinases 53 2e-06
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 53 2e-06
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 53 2e-06
CE24991 [T] KOG0197 Tyrosine kinases 53 2e-06
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 53 2e-06
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 53 2e-06
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 53 2e-06
SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinas... 52 3e-06
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 52 3e-06
CE18454 [T] KOG4717 Serine/threonine protein kinase 52 3e-06
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 52 3e-06
CE15235 [R] KOG0589 Serine/threonine protein kinase 52 3e-06
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 52 3e-06
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 52 4e-06
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 52 4e-06
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 51 6e-06
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 51 6e-06
At3g44850 [T] KOG1290 Serine/threonine protein kinase 51 8e-06
7303073 [T] KOG1290 Serine/threonine protein kinase 51 8e-06
7296535 [T] KOG1290 Serine/threonine protein kinase 51 8e-06
Hs15718680 [T] KOG0197 Tyrosine kinases 50 1e-05
Hs13489054 [T] KOG0581 Mitogen-activated protein kinase kinase (... 50 1e-05
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 50 1e-05
CE03979 [T] KOG0614 cGMP-dependent protein kinase 50 1e-05
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 50 1e-05
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 50 1e-05
7301213 [R] KOG0589 Serine/threonine protein kinase 50 1e-05
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 417 bits (1072), Expect = e-116
Identities = 239/567 (42%), Positives = 330/567 (58%), Gaps = 53/567 (9%)
Query: 13 IPPDVNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLM 72
+PPDV+NPP IPLK + RY +I++LG GSFG VTLA+ + +++ + + TLM
Sbjct: 18 VPPDVDNPPLSIPLKTLSDRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRG-TLM 76
Query: 73 DQTLIRNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEM 132
DQ +N Q N+ K +G+VAIKTMM +L TL DYTRVREIKFIL IPA+ +L+ I+E+
Sbjct: 77 DQP--KNGHQ-NYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEV 133
Query: 133 FIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXX 192
FID Y LHIVMECMEQN+YQ+MKHR+RRVFS+P+L+SIL QILAG
Sbjct: 134 FIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRD 193
Query: 193 XXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSP 252
PENILI+PS +YF K+++ Y DNYV+KLAD+GLARHV N++PYT YVSTRWYRSP
Sbjct: 194 LKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSP 253
Query: 253 EILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP--DHSINGK 310
EILLR GYYSKPLDIWA+GCV VE+ F LFPG++E DQIW+IL++LG+P
Sbjct: 254 EILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRSDFVNT 313
Query: 311 EHF-----GGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSE 365
H GG W D+ L LN + PYVEG ++ +L + QL DL +VV CL+W+P+E
Sbjct: 314 NHITAPPPGGFWDDASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNE 373
Query: 366 RATANEICALPYFKEYVMREASLAKTNNGTASKNKDNTALANKLAANPSISNQWSRILSG 425
RATA E+C +P+F+ V + A N NT A A ++ I
Sbjct: 374 RATAQELCEMPFFENTVASQVD--------ARGNVTNTEQALIFAGINPVATNTKPIY-- 423
Query: 426 LPHNPELGIVPSFNSPQKLPKVQKNNQMNCVTDKSQQQPRRGGVASWFKFSTQKNHVNIN 485
FNS KLP ++N ++ + + K T +N
Sbjct: 424 ------------FNSSTKLPAETESNDIDISNNDHDSHAMCSPTLNQEKL-TLVEFLNEF 470
Query: 486 PNTNNDEKILTSVNTNTNSQKNQGIVEKKQQEQQVNAHNERLDSSTNANGNSIPDINLIG 545
+ND+ + V T++ + +++ + +++ N +PD ++
Sbjct: 471 VEEDNDDHSIPDVGTDSTISDS---IDETELSKEIR---------NNLALCQLPDEEVLD 518
Query: 546 HA-------NNDNEVFTIELDDSMETM 565
H+ ND E+ + D+ME +
Sbjct: 519 HSLSNIRQLTNDIEIINKDEADNMEQL 545
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 214 bits (546), Expect = 3e-55
Identities = 132/392 (33%), Positives = 206/392 (51%), Gaps = 50/392 (12%)
Query: 28 NIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYY 87
+ID YNV++++G G+FGSV LA T
Sbjct: 31 SIDEVYNVVRKVGDGTFGSVYLATTKTP-------------------------------- 58
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMEC 147
K +VAIK+M +L + D TR+RE+ +L++ ++N+V I++++ID LHIVME
Sbjct: 59 -SKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENENIVNIFDLYIDQ-FRCLHIVMEF 116
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
++ N+YQL+ RK +L ++ I+ QI G PENILIS
Sbjct: 117 LDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHTNGFFHRDMKPENILIS------ 170
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
++ S ++ VK+AD+GLAR +N+R PYT YVSTRWYR+PE+LLR YYS P+DI
Sbjct: 171 ------SNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPELLLRDSYYSFPVDI 224
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPD-HSINGKEHFGGSWLDSKPLYQA 326
+A GC+ E+AT P+FPG+D+ DQ++++ ++LGSPD S N + GG W ++ L
Sbjct: 225 YAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDEQSQNTGDKGGGIWDRAELLANK 284
Query: 327 LNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREA 386
L P + D+ P +++ LKW+P++R TA L + + +A
Sbjct: 285 LGISLPKMAPLDFGDLFSPPWNLAFASMLSQLLKWDPAKRPTAEMCLDLEFCRVSAPADA 344
Query: 387 SLAKTNNGTASKNKDNTALANKLAANPSISNQ 418
+K +KN D + ++ SI ++
Sbjct: 345 VASKEE---VNKNTDFRVSISYFPSSSSIPDE 373
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 182 bits (462), Expect = 2e-45
Identities = 107/348 (30%), Positives = 177/348 (50%), Gaps = 65/348 (18%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY I++LG G++GSV L R++E
Sbjct: 3 RYTTIRQLGDGTYGSVLLG---------------------------RSIESGE------- 28
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
++AIK M + + + +RE+K + ++ H N+V + E+ ++ HL+ + E M++N
Sbjct: 29 LIAIKKMKRKFYSWEECMNLREVKSLKKLN-HANVVKLKEVIREND--HLYFIFEYMKEN 85
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+YQL+K R + +F +R+I++QIL G PEN+L
Sbjct: 86 LYQLIKERNK-LFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPE------- 137
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYG 271
+VK+AD+GLAR + ++ PYT YVSTRWYR+PE+LLR YS P+D+WA G
Sbjct: 138 ----------LVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVG 187
Query: 272 CVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEF 331
C++ E+ T PLFPG+ E D I++I +LG+P + W + L A+N+ +
Sbjct: 188 CIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKT---------DWPEGYQLSSAMNFRW 238
Query: 332 PYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
P ++ ++PN E + ++ L+W+P +R TA++ PYF+
Sbjct: 239 PQCVPNNLKTLIPNASSEAV-QLLRDMLQWDPKKRPTASQALRYPYFQ 285
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 181 bits (459), Expect = 4e-45
Identities = 107/348 (30%), Positives = 176/348 (49%), Gaps = 65/348 (18%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY I++LG G++GSV L R++E
Sbjct: 3 RYTTIRQLGDGTYGSVLLG---------------------------RSIESGE------- 28
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
++AIK M + + + RE+K + ++ H N+V + E+ ++ HL+ + E M++N
Sbjct: 29 LIAIKKMKRKFYSWEECMNQREVKSLKKLN-HANVVKLKEVIREND--HLYFIFEYMKEN 85
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+YQL+K R + +F +R+I++QIL G PEN+L
Sbjct: 86 LYQLIKERNK-LFPESAIRNIMYQILQGLAFIHKLGFFHRDLKPENLLCMGPE------- 137
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYG 271
+VK+AD+GLAR + ++ PYT YVSTRWYR+PE+LLR YS P+D+WA G
Sbjct: 138 ----------LVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVG 187
Query: 272 CVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEF 331
C++ E+ T PLFPG+ E D I++I +LG+P + W + L A+N+ +
Sbjct: 188 CIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKT---------DWPEGYQLSSAMNFRW 238
Query: 332 PYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
P ++ ++PN E + ++ L+W+P +R TA++ PYF+
Sbjct: 239 PQCVPNNLKTLIPNASSEAV-QLLRDMLQWDPKKRPTASQALRYPYFQ 285
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 180 bits (457), Expect = 6e-45
Identities = 116/384 (30%), Positives = 190/384 (49%), Gaps = 70/384 (18%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY +++LG G++GSV + ++ N S
Sbjct: 3 RYTTMRQLGDGTYGSVLMGKS----NESGE------------------------------ 28
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
+VAIK M + + + +RE+K + ++ H N++ + E+ ++ HL+ + E M++N
Sbjct: 29 LVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANVIKLKEVIREND--HLYFIFEYMKEN 85
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+YQLMK R + +F +R+I++QIL G PEN+L
Sbjct: 86 LYQLMKDRNK-LFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPE------- 137
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYG 271
+VK+AD+GLAR + ++ PYT YVSTRWYR+PE+LLR YS P+D+WA G
Sbjct: 138 ----------LVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVG 187
Query: 272 CVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEF 331
++ EL PLFPG+ E D+I++I +LG+P S W + L ++N+ F
Sbjct: 188 SIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKS---------DWPEGYQLASSMNFRF 238
Query: 332 PYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKT 391
P ++ ++PN E + ++T L W+P +R TA++ PYF+ + L +
Sbjct: 239 PQCVPINLKTLIPNASNEAI-QLMTEMLNWDPKKRPTASQALKHPYFQVGQV----LGPS 293
Query: 392 NNGTASKNKDNTALANKLAANPSI 415
+N SK N L L + PS+
Sbjct: 294 SNHLESKQSLNKQL-QPLESKPSL 316
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 176 bits (447), Expect = 9e-44
Identities = 117/367 (31%), Positives = 177/367 (47%), Gaps = 48/367 (13%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY V Q+LG GSFG+V LA+ +++N Y+
Sbjct: 20 RYLVKQKLGDGSFGTVYLAQR----------------------------KEKNGLYETVA 51
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
+ +K P H+ ++RE + +I H L+ + E F+D ++ +VME M+ N
Sbjct: 52 VKKLKNSSKPKPK-HELLKLRESLALRKISKHPCLIDLLETFMDP-YRNIFLVMEFMDCN 109
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
++QL K R+ R+F+ T +IL QI++G PENIL+ K
Sbjct: 110 LFQLFKRRQGRLFTKETAFNILLQIISGIEHIHKHGFMHRDIKPENILV---------KR 160
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYG 271
+ S Y +KL D+GLAR + P T YVSTRWYR+PE+LLR G Y+ +D++A+G
Sbjct: 161 ISPKPISSRYSIKLGDFGLARPSVSSDPLTEYVSTRWYRAPELLLRSGSYNHSVDLYAFG 220
Query: 272 CVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEF 331
C+V E+ + PLFPG +ETDQ+ R+ ++LG+P H+ W +K L + L +
Sbjct: 221 CIVFEIYSLKPLFPGRNETDQLNRVCEILGNPGIDELDTLHY---WSQAKELAKRLGFML 277
Query: 332 PYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKT 391
P + I+ +LP E ++ L WNP R TA Y KE A
Sbjct: 278 PPTKPYPIQKLLPQNCPEGHAKMIPCLLAWNPDVRPTAK------YCKEVFFPLPPSASK 331
Query: 392 NNGTASK 398
+N K
Sbjct: 332 SNSVPQK 338
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 173 bits (438), Expect = 1e-42
Identities = 134/475 (28%), Positives = 217/475 (45%), Gaps = 83/475 (17%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNI 152
VAIK M + + + +RE+K + ++ +H N+V + E+ ++ L+ V E M++N+
Sbjct: 30 VAIKRMKRKYYSWEEAMNLREVKSLKKL-SHPNIVKLKEVIRENDT--LYFVFEYMKENL 86
Query: 153 YQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWL 212
YQ++K R + P L+SILFQ+L G PEN+L S
Sbjct: 87 YQMIKDRDTHLPE-PELKSILFQVLTGLAFMHRHGFFHRDLKPENLLCSGPD-------- 137
Query: 213 EDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGC 272
++K+AD+GLAR + +R P+T YVSTRWYR+PE+LL Y +D+WA GC
Sbjct: 138 ---------LIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGSTIDLWAMGC 188
Query: 273 VVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFP 332
++ EL TF PLFPGS E DQ+++I +LG+PD W D L +++ +P
Sbjct: 189 IMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKD---------DWPDGYRLASMIHFRYP 239
Query: 333 YVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTN 392
+ V+ L D++ L ++P +R TA + PYF + ++ S
Sbjct: 240 DCIKVPLSSVVSRCSQNGL-DLLEDMLAYDPDKRPTAQQSLKYPYF--HALKRIS----- 291
Query: 393 NGTASKNKDNTALANKLAAN-----PSISNQWSRILSGLPHNPELGIVPSFNSPQKLPKV 447
+ K N L +K AA+ S+SN + LP +L V
Sbjct: 292 --PTAATKANVRLNSKYAASNGHPVQSVSN------NVLPVQEKLQAVTELLH------- 336
Query: 448 QKNNQMNCVTDKSQQQ---PRRGGVASWFK----FSTQK-----NHVNIN---------- 485
Q NN MN ++ + P+ GGV ++ F T +H + +
Sbjct: 337 QTNNNMNSHSNLGKNNNLAPKNGGVPRKYQPKLSFLTTSEMGAGSHADSSSLVGGATVDG 396
Query: 486 ---PNTNNDEKILTSVNTNTNSQKNQGIVEKKQQEQQVNAHNERLDSSTNANGNS 537
P N + + + N N + G+ Q +QQ H+ + ST ++ N+
Sbjct: 397 VPVPQHQNGGESINDIYLNRNISQLFGLPAGPQHQQQQQVHHPNVSFSTTSSRNA 451
>At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 530
Score = 172 bits (437), Expect = 1e-42
Identities = 135/489 (27%), Positives = 221/489 (44%), Gaps = 89/489 (18%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY +++E+G G+FG+V A +N ++ + E +Y +
Sbjct: 3 RYTLLKEVGDGTFGNVWRA-----VNKQTNEVGT-----------------EVFYVQ--- 37
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
VAIK M + + + +RE+K + ++ H N+V + E+ ++ + L+ V E ME N
Sbjct: 38 -VAIKRMKKKYFSWEECVNLREVKSLSRMN-HPNIVKLKEVIRENDI--LYFVFEYMECN 93
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+YQLMK R + F+ +R+ FQ+ G PEN+L+S
Sbjct: 94 LYQLMKDRPKH-FAESDIRNWCFQVFQGLSYMHQRGYFHRDLKPENLLVSKD-------- 144
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYG 271
V+K+AD GLAR +++ PYT YVSTRWYR+PE+LL+ Y+ +D+WA G
Sbjct: 145 ----------VIKIADLGLAREIDSSPPYTEYVSTRWYRAPEVLLQSYVYTSKVDMWAMG 194
Query: 272 CVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEF 331
++ EL + PLFPG+ E D+I++I ++GSP +WL+ L +NY+F
Sbjct: 195 AIMAELLSLRPLFPGASEADEIYKICSVIGSPTEE---------TWLEGLNLASVINYQF 245
Query: 332 PYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE-YVMREASLAK 390
P G + V+P D +++ W+P R T E P+F+ Y + + K
Sbjct: 246 PQFPGVHLSSVMPYAS-ADAVNLIERLCSWDPCNRPTTAEALQHPFFQSCYYIPPSLRPK 304
Query: 391 TNNGTASKNKDNTALANKLAANPSISNQWSRILSGLPHNPELGIVPSFNSPQKLPKVQKN 450
+ S + + +L A P+ + + P N + P N+P +
Sbjct: 305 LSEPRGSLEQQQS--VKRLPAAPTYN-------ANKPLNTY--VTPKTNAP-------FS 346
Query: 451 NQMNCVTDKSQQQPRRGGVASWFKFSTQ---KNHVN--INPNTN-------NDEKILTSV 498
N +N P GV S+ T N VN + P N +K+ T+
Sbjct: 347 NGVNSYVTPKTNAPFSNGVNSYVTAKTNAPFSNGVNNYVAPKMNAPFDNGATQQKVDTTN 406
Query: 499 NTNTNSQKN 507
N N N+ N
Sbjct: 407 NNNQNTAWN 415
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 171 bits (433), Expect = 4e-42
Identities = 129/458 (28%), Positives = 209/458 (45%), Gaps = 58/458 (12%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNI 152
VAIK M + + + +RE+K + ++ H N++ + E+ ++ + L+ V E M++N+
Sbjct: 71 VAIKRMKKKFYSWEEAMSLREVKSLKKLN-HPNIIKLREVIRENDI--LYFVFEFMQENL 127
Query: 153 YQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWL 212
Y+LMK R R F +R+I++Q+L G PENI+ + +
Sbjct: 128 YELMKDRDR-YFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTE-------- 178
Query: 213 EDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGC 272
+VK+AD+GLAR + ++ PYT YVSTRWYR+PEILLR Y+ P+D+WA GC
Sbjct: 179 ---------LVKIADFGLAREIRSKPPYTDYVSTRWYRAPEILLRSTSYNSPIDMWALGC 229
Query: 273 VVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFP 332
++ EL PLFPG+ E DQ+++I+ +LG+P+ W + L A+N+ F
Sbjct: 230 IMAELYILRPLFPGTSEMDQLFKIISILGTPNKD---------EWPEGYQLASAMNFRFQ 280
Query: 333 YVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFK-------EYVMRE 385
V + V+ E + ++ + WNP +R AN+ YF+ V +
Sbjct: 281 QVVATPMEQVVNTISKEGM-KLMMDMMLWNPEKRPNANQSLRYKYFQVAEKLGAPVVSQP 339
Query: 386 ASLAKTNNGTASKNKDNTALANKLAANPSISN------QWSRILS-----GLPHNPELGI 434
A + AS D A+ K A I + Q ++++ LP N E
Sbjct: 340 APGSIRKTSAASVKSDTKAMTAKAAKKDYIGSENVSPQQPAKVIDRHINRNLPLNKETLF 399
Query: 435 VPSFNSPQKLPKVQ--KNNQMNCVTDKSQQQPRRGGVASWFKFSTQ-----KNHVNINPN 487
S N P K K KS+ P G V + FK S + ++N +
Sbjct: 400 EKSDNKPLGPTKSNEAKPTAKEIYLSKSKYVP--GTVKNKFKKSLKWLDLLIPYLNCQVS 457
Query: 488 TNNDEKILTSVNTNTNSQKNQGIVEKKQQEQQVNAHNE 525
+ + + + N T + K KK+ V E
Sbjct: 458 KDTHQNQIMTTNGLTGTTKTTTFSAKKEGRTAVQTRFE 495
>At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 256
Score = 167 bits (422), Expect = 7e-41
Identities = 88/272 (32%), Positives = 152/272 (55%), Gaps = 32/272 (11%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLR 170
+RE+K + ++ H N+V + E+ ++ + L+ V E ME N+YQLMK R++ +F+ ++
Sbjct: 14 LREVKSLRRMN-HPNIVKLKEVIRENDI--LYFVFEYMECNLYQLMKDRQK-LFAEADIK 69
Query: 171 SILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGL 230
+ FQ+ G PEN+L+S ++K+AD+GL
Sbjct: 70 NWCFQVFQGLSYMHQRGYFHRDLKPENLLVSKD------------------IIKIADFGL 111
Query: 231 ARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDET 290
AR VN+ P+T YVSTRWYR+PE+LL+ Y+ +D+WA G ++ EL + P+FPG+ E
Sbjct: 112 AREVNSSPPFTEYVSTRWYRAPEVLLQSYVYTSKVDMWAMGAIMAELLSLRPIFPGASEA 171
Query: 291 DQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLED 350
D+I++I ++G+P +WL+ L +NY+FP + G + ++P+ ED
Sbjct: 172 DEIYKICSVIGTPTEE---------TWLEGLNLANTINYQFPQLPGVPLSSLMPSAS-ED 221
Query: 351 LYDVVTSCLKWNPSERATANEICALPYFKEYV 382
+++ W+PS R TA E+ P+F+ ++
Sbjct: 222 AINLIERLCSWDPSSRPTAAEVLQHPFFQVHL 253
>At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 443
Score = 158 bits (399), Expect = 3e-38
Identities = 100/347 (28%), Positives = 167/347 (47%), Gaps = 66/347 (19%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY +++ELG G+ GSV A +
Sbjct: 11 RYKILEELGDGTCGSVYKAVNLETYE---------------------------------- 36
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
+VA+K M + + +RE+K + ++ H +++ + E+ + + L + ECM+ N
Sbjct: 37 VVAVKKMKRKFYYWEECVNLREVKALRKLN-HPHIIKLKEIVREHN--ELFFIFECMDHN 93
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+Y +MK R+R FS +RS + Q+L G PEN+L++
Sbjct: 94 LYHIMKERERP-FSEGEIRSFMSQMLQGLAHMHKNGYFHRDLKPENLLVT---------- 142
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYG 271
N ++K+AD+GLAR V + PYT YVSTRWYR+PE+LL+ Y+ +D+WA G
Sbjct: 143 --------NNILKIADFGLAREVASMPPYTEYVSTRWYRAPEVLLQSSLYTPAVDMWAVG 194
Query: 272 CVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEF 331
++ EL +PLFPG E DQ+++I +LG PD + ++ ++K + + ++
Sbjct: 195 AILAELYALTPLFPGESEIDQLYKICCVLGKPDWT---------TFPEAKSISRIMSISH 245
Query: 332 PYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
I D+LPN E + D++ W+P +R TA+E P+F
Sbjct: 246 TEFPQTRIADLLPNAAPEAI-DLINRLCSWDPLKRPTADEALNHPFF 291
>Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 419
Score = 152 bits (383), Expect = 2e-36
Identities = 99/348 (28%), Positives = 163/348 (46%), Gaps = 64/348 (18%)
Query: 33 YNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKGI 92
Y I ++G+G+F V +++ D N YY
Sbjct: 4 YKAIGKIGEGTFSEVMKMQSLRDGN----------------------------YY----- 30
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNI 152
A K M R ++ +REI+ + ++ H N++ ++E+ D L ++ E M+ NI
Sbjct: 31 -ACKQMKQRFESIEQVNNLREIQALRRLNPHPNILMLHEVVFDRKSGSLALICELMDMNI 89
Query: 153 YQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWL 212
Y+L++ R R S + ++Q+ PENILI
Sbjct: 90 YELIRGR-RYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIKQD--------- 139
Query: 213 EDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGC 272
V+KL D+G R V ++ PYT Y+STRWYR+PE LL G+Y+ +D+W+ GC
Sbjct: 140 ---------VLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGC 190
Query: 273 VVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFP 332
V E+A+ PLFPG +E DQI +I D++G+P I L +A+N++FP
Sbjct: 191 VFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKI----------LTKFKQSRAMNFDFP 240
Query: 333 YVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ +G I + N + L ++ + + ++P ER A++ PYF+E
Sbjct: 241 FKKGSGIPLLTTNLSPQCL-SLLHAMVAYDPDERIAAHQALQHPYFQE 287
>CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 763
Score = 125 bits (315), Expect = 2e-28
Identities = 83/284 (29%), Positives = 136/284 (47%), Gaps = 38/284 (13%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQL---MKHRKRRVFS 165
T +REI +L+ AH+N+V + E+ + + +++ ME +E ++ L M+ R +R F
Sbjct: 442 TALREINMLLKAGAHENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQR-FK 500
Query: 166 LPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
++++ Q+L+G N+LIS S ++K+
Sbjct: 501 TGQQKTLMSQLLSGIEHMHKLWILHRDLKTSNLLISHSG-----------------ILKI 543
Query: 226 ADYGLARH------VNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELAT 279
AD+GLAR + R T V T WYRSPE+LL YS P+D+W+ GC++ E
Sbjct: 544 ADFGLAREYGEARDIEKRMKLTPIVVTLWYRSPELLLEPKTYSTPVDMWSIGCIMAEFIM 603
Query: 280 FSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTI 339
P+F G E +Q+ +I ++G+P I W D K L EFP V+ +
Sbjct: 604 MKPMFQGDSEPNQVHQIFQMMGTPTEQI---------WPDIKELKVWNMVEFPPVKPGQL 654
Query: 340 RDVLPNPQL--EDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
R + +L E +D++ L NP+ R TA+E +F E+
Sbjct: 655 RRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWFSEH 698
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 120 bits (301), Expect = 8e-27
Identities = 83/273 (30%), Positives = 133/273 (48%), Gaps = 36/273 (13%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REI + ++ H N+V + ++ ++ L++V E + Q++ + M L
Sbjct: 47 TAIREISLLKELK-HPNIVRLLDVVHNER--KLYLVFEFLSQDLKKYMDSTPGSELPLHL 103
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
++S LFQ+L G P+N+LI+ + +KLAD+
Sbjct: 104 IKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLIN-----------------ELGAIKLADF 146
Query: 229 GLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLAR YT V T WYR+PEILL +Y+ +DIW+ GC+ E+ T LFPG
Sbjct: 147 GLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGD 206
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSW--LDSKPLYQALNYEFPYVEGKTIRDVLPN 345
E DQ++RI +LG+P +W + P Y+ FP K + +++PN
Sbjct: 207 SEIDQLFRIFRMLGTPSED---------TWPGVTQLPDYKG---SFPKWTRKGLEEIVPN 254
Query: 346 PQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
+ E D++ L+++PS+R TA A PYF
Sbjct: 255 LEPEG-RDLLMQLLQYDPSQRITAKTALAHPYF 286
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 119 bits (299), Expect = 1e-26
Identities = 89/292 (30%), Positives = 140/292 (47%), Gaps = 39/292 (13%)
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
IVAIK R + +REIKF+ Q H+NLV + E+F +H+V E ++
Sbjct: 29 IVAIKIFYERPEQSVNKIAMREIKFLKQFH-HENLVNLIEVFRQKK--KIHLVFEFIDHT 85
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+ ++H + S LR LFQIL PENIL+S S
Sbjct: 86 VLDELQHYCHGLES-KRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSG------- 137
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAY 270
+ KL D+G AR + YT YV+TRWYR+PE++L+ Y KP+DIWA
Sbjct: 138 ----------ITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPVDIWAL 187
Query: 271 GCVVVELATFSPLFPGSDETDQIWRILDLLG--SP--DHSINGKEHFGGSWLDSKPLYQA 326
GC+++E+AT +P P S + D + +I+ +G SP + + F G L +
Sbjct: 188 GCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPKN 247
Query: 327 LNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
++P + G L D+V +CL+ +P++R +++++ YF
Sbjct: 248 ARKKYPKLNGL-------------LADIVHACLQIDPADRISSSDLLHHEYF 286
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 119 bits (298), Expect = 2e-26
Identities = 85/275 (30%), Positives = 133/275 (47%), Gaps = 36/275 (13%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REI + ++ H N+V + ++ ++ L++V E + Q++ + M LP
Sbjct: 47 TAIREISLLKELN-HPNIVKLLDVIHTEN--KLYLVFEFLHQDLKKFMDASALTGIPLPL 103
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
++S LFQ+L G P+N+LI+ +KLAD+
Sbjct: 104 IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEG-----------------AIKLADF 146
Query: 229 GLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLAR YT V T WYR+PEILL YYS +DIW+ GC+ E+ T LFPG
Sbjct: 147 GLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGD 206
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSW--LDSKPLYQALNYEFPYVEGKTIRDVLPN 345
E DQ++RI LG+PD + W + S P Y+ FP + V+P
Sbjct: 207 SEIDQLFRIFRTLGTPDEVV---------WPGVTSMPDYKP---SFPKWARQDFSKVVP- 253
Query: 346 PQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
P ED +++ L ++P++R +A A P+F++
Sbjct: 254 PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD 288
>CE29318 [T] KOG0660 Mitogen-activated protein kinase
Length = 474
Score = 118 bits (295), Expect = 4e-26
Identities = 100/379 (26%), Positives = 162/379 (42%), Gaps = 65/379 (17%)
Query: 17 VNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTL 76
+ N F IP + D N I+ LG GSFG+V + +SA +
Sbjct: 103 IRNITFAIP-EGYDVEPNSIEYLGGGSFGNV--------IKTSAVCRDGL---------- 143
Query: 77 IRNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
+ VAIK M H R+ +LQ+ H N++ +++ D
Sbjct: 144 -------------RRYVAIKKMREPFFDPHHARRIFRETKLLQLMRHDNIICALDIYTPD 190
Query: 137 S---LYHLHIVMECMEQNIYQLMKHRK---RRVFSLPTLRSILFQILAGXXXXXXXXXXX 190
+++V E +++YQ++K ++ RRV + ++ I++QI+
Sbjct: 191 EENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRALKYIHSANIIH 250
Query: 191 XXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWY 249
P N+ ++ D+ + + D+GLAR + + + T YV TRWY
Sbjct: 251 RDLKPGNLALT-----------------DDSDLMILDFGLARSLEKKDTSLTQYVQTRWY 293
Query: 250 RSPEILLRK-GYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSIN 308
RSPE++ K Y+ D+W+ GC+ EL T PLFPG + Q RI L GSPD +
Sbjct: 294 RSPEVIYWKIDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELL 353
Query: 309 GKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP--NPQLEDLYDVVTSCLKWNPSER 366
K D+ +A+ + + + RDV NP ED D++ L +P +R
Sbjct: 354 TKIE-----NDNSSAIKAVIQSYTTHKRRNFRDVFSAHNPS-EDFIDLLEKLLVLDPEKR 407
Query: 367 ATANEICALPYFKEYVMRE 385
T E PY E+ + E
Sbjct: 408 ITVEEAIQHPYLAEFSLPE 426
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 117 bits (294), Expect = 5e-26
Identities = 83/274 (30%), Positives = 133/274 (48%), Gaps = 31/274 (11%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REI+ + I H N+V + ++ + L +++VME ME ++ L+ + F
Sbjct: 117 TSLREIESLSSI-RHDNIVELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPED-FLQSE 174
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
+++++ Q+LA P N+L++ + +KLAD+
Sbjct: 175 VKTLMLQLLAATAFMHHHWYLHRDLKPSNLLMNNTGE-----------------IKLADF 217
Query: 229 GLARHVNN-RSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLAR V+ +S T V T WYR+PE+LL Y K +D+W+ GC+ E+ T +PLF G
Sbjct: 218 GLARPVSEPKSSLTRLVVTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGK 277
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKT-IRDVLPNP 346
E DQ+++I +LLG P W L A + P V + IR +PN
Sbjct: 278 SELDQLYKIFNLLGYPTRE---------EWPQYFLLPYANKIKHPTVPTHSKIRTSIPN- 327
Query: 347 QLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ YD++ L NP++R +A E PYF E
Sbjct: 328 LTGNAYDLLNRLLSLNPAKRISAKEALEHPYFYE 361
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 116 bits (291), Expect = 1e-25
Identities = 92/299 (30%), Positives = 144/299 (47%), Gaps = 31/299 (10%)
Query: 88 KKKG-IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVM 145
KK G IVA+K + M + T +REI +L H ++V + E+ + SL + +VM
Sbjct: 426 KKTGEIVALKKVKMEKEREGFPLTSLREINILLSFH-HPSIVDVKEVVVGSSLDSIFMVM 484
Query: 146 ECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHR 205
E ME ++ LM+ K+R FS ++ ++ Q+L G N+L++
Sbjct: 485 EYMEHDLKALMETMKQR-FSQSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLN---- 539
Query: 206 YFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKP 264
+ +K+ D+GLAR + PYT V T WYR+PE+LL YS
Sbjct: 540 -------------NRGELKICDFGLARQYGSPLKPYTHLVVTLWYRAPELLLGAKQYSTA 586
Query: 265 LDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI-NGKEHFGGSWLD-SKP 322
+D+W+ GC++ EL +PLF G E DQ+ +I +LG+P+ SI G G ++ K
Sbjct: 587 IDMWSLGCIMAELLMKAPLFNGKTEFDQLDKIFRILGTPNESIWPGFSKLPGVKVNFVKH 646
Query: 323 LYQALNYEFPYVEGKTIRDVLPNPQLEDL-YDVVTSCLKWNPSERATANEICALPYFKE 380
Y L +FP P L D +D++ L ++P R T NE +F+E
Sbjct: 647 QYNLLRKKFP------ATSFTGAPVLSDAGFDLLNKLLTYDPERRITVNEALKHDWFRE 699
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 115 bits (289), Expect = 2e-25
Identities = 88/291 (30%), Positives = 136/291 (46%), Gaps = 37/291 (12%)
Query: 93 VAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTI---YEMFIDDSLYHLHIVMECM 148
VAIK + N D R +REIK + + H N++ I E+ + ++IV E M
Sbjct: 59 VAIKKIANAFDNRVDAKRTLREIKLLSHMD-HDNVIKIKDIIELPEKERFEDVYIVYELM 117
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ +++Q++ R + + + L+QIL G P N++++
Sbjct: 118 DTDLHQII--RSTQTLTDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLNT------ 169
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
N +K+ D+GLAR N T YV TRWYR+PE+LL Y+ +DIW
Sbjct: 170 -----------NCDLKICDFGLARTSNETEIMTEYVVTRWYRAPELLLNSSEYTGAIDIW 218
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALN 328
+ GC+ +E+ LFPG D Q+ I +LLGSPD S LD A
Sbjct: 219 SVGCIFMEILRRETLFPGKDYVQQLKLITELLGSPDDSD----------LDFLRSDNARK 268
Query: 329 Y--EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
Y + P+V+ ++ R+ PN L D+ L ++PS+R T +E PY
Sbjct: 269 YVKQLPHVQKQSFREKFPNISPMAL-DLAEKMLVFDPSKRITVDEALKQPY 318
>YHR030c [T] KOG0660 Mitogen-activated protein kinase
Length = 484
Score = 115 bits (288), Expect = 2e-25
Identities = 96/361 (26%), Positives = 164/361 (44%), Gaps = 72/361 (19%)
Query: 28 NIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYY 87
++D R+ +I+E+G G++G V S+ + E D T
Sbjct: 18 SVDKRFQLIKEIGHGAYGIVC---------------SARFAEAAEDTT------------ 50
Query: 88 KKKGIVAIKTMMNRLP-TLHDYTRVREIKFILQIPAHKNLVTIYEMFI----DDSLYHLH 142
VAIK + N TL +RE+K + HKN+ +Y+M I D S+ L+
Sbjct: 51 -----VAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLY 105
Query: 143 IVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISP 202
+ E ME +++Q++K + + +S +QIL G P N+L++
Sbjct: 106 LYEELMECDMHQIIK--SGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNA 163
Query: 203 SHRYFSKKWLEDDNYSDNYVVKLADYGLARH-----VNNRSPYTTYVSTRWYRSPEILLR 257
+ +K+ D+GLAR V N T YV+TRWYR+PEI+L
Sbjct: 164 DCQ-----------------LKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLS 206
Query: 258 KGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS-PDHSINGKEHFGGS 316
Y+K +D+W+ GC++ E P+F G D +Q+ +IL +LG+ PD ++
Sbjct: 207 YQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRR------- 259
Query: 317 WLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALP 376
+ SK + Q ++ ++ ++ PN + L D++ L ++P +R T +E P
Sbjct: 260 -IGSKNV-QDYIHQLGFIPKVPFVNLYPNANSQAL-DLLEQMLAFDPQKRITVDEALEHP 316
Query: 377 Y 377
Y
Sbjct: 317 Y 317
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 115 bits (287), Expect = 3e-25
Identities = 98/368 (26%), Positives = 165/368 (44%), Gaps = 85/368 (23%)
Query: 28 NIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYY 87
++ RY +Q +G+G++G V+ A YD +
Sbjct: 37 DVGPRYTQLQYIGEGAYGMVSSA---YD-------------------------------H 62
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHL---HIV 144
+K VAIK + + +REI+ +L+ H+N++ I ++ +L + +IV
Sbjct: 63 VRKTRVAIKKISPFEHQTYCQRTLREIQILLRF-RHENVIGIRDILRASTLEAMRDVYIV 121
Query: 145 MECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH 204
+ ME ++Y+L+K ++ S + L+QIL G P N+LI+ +
Sbjct: 122 QDLMETDLYKLLKSQQ---LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTC 178
Query: 205 RYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYT----TYVSTRWYRSPEILLRKGY 260
+K+ D+GLAR + +T YV+TRWYR+PEI+L
Sbjct: 179 D-----------------LKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKG 221
Query: 261 YSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHS-----INGKEHFGG 315
Y+K +DIW+ GC++ E+ + P+FPG DQ+ IL +LGSP IN K
Sbjct: 222 YTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKAR--- 278
Query: 316 SWLDSKPLYQALNYE--FPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEIC 373
++L S P + + FP + K + D++ L +NP++R T E
Sbjct: 279 NYLQSLPSKTKVAWAKLFPKSDSKAL-------------DLLDRMLTFNPNKRITVEEAL 325
Query: 374 ALPYFKEY 381
A PY ++Y
Sbjct: 326 AHPYLEQY 333
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 115 bits (287), Expect = 3e-25
Identities = 90/314 (28%), Positives = 138/314 (43%), Gaps = 35/314 (11%)
Query: 92 IVAIKTMMNRLPTLH-DYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQ 150
IVAIK + H +REI+ + Q+ H+NLV + E+F + LH+V E ++
Sbjct: 29 IVAIKKFVETEDDPHIKKIALREIRMLKQLK-HQNLVGLIEVFKRNR--KLHLVFELCDR 85
Query: 151 NIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKK 210
+ ++ V ++ I++Q+L PENI ++ + +
Sbjct: 86 TVLHELEKNPHGVND-ELIKKIIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQ----- 139
Query: 211 WLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAY 270
VKL D+G AR +N YT YV+TRWYRSPE+L+ Y P+DIWA
Sbjct: 140 ------------VKLGDFGFARIINTTEMYTDYVATRWYRSPELLVGDVQYGPPVDIWAV 187
Query: 271 GCVVVELATFSPLFPGSDETDQIWRILDLLGS--PDHSINGKEHFGGSWLDSKPLYQALN 328
GCV EL T L+PG + DQ++ I LG P H S + + L+
Sbjct: 188 GCVYAELLTGEALWPGRSDIDQLYHIRKTLGEFLPRHI---------SIFRTNQFFFGLS 238
Query: 329 YEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASL 388
P + + LPN L D + C + +P R + +E+ F +++R
Sbjct: 239 IPEP-EHLEPLPSKLPNASSAQL-DFLQKCFEMSPDRRFSCSELMLHGIFSNWILRIRQD 296
Query: 389 AKTNNGTASKNKDN 402
T G SK N
Sbjct: 297 ESTPTGLTSKRSPN 310
>Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 358
Score = 114 bits (285), Expect = 6e-25
Identities = 87/293 (29%), Positives = 133/293 (44%), Gaps = 40/293 (13%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLR 170
+REI+ + Q+ H NLV + E+F LH+V E + + + +R V ++
Sbjct: 50 LREIRMLKQLK-HPNLVNLLEVFRRKR--RLHLVFEYCDHTVLHELDRYQRGVPE-HLVK 105
Query: 171 SILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGL 230
SI +Q L PENILI+ + V+KL D+G
Sbjct: 106 SITWQTLQAVNFCHKHNCIHRDVKPENILITK-----------------HSVIKLCDFGF 148
Query: 231 ARHVNNRSPY-TTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDE 289
AR + S Y T YV+TRWYRSPE+L+ Y P+D+WA GCV EL + PL+PG +
Sbjct: 149 ARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSD 208
Query: 290 TDQIWRILDLLGS--PDHS--INGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPN 345
DQ++ I LG P H + ++F G + + L +FP + +
Sbjct: 209 VDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKIPDPEDMEPLELKFPNISYPAL------ 262
Query: 346 PQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNGTASK 398
++ CL +P+ER T ++ PYF E + LAK ++ K
Sbjct: 263 -------GLLKGCLHMDPTERLTCEQLLHHPYF-ENIREIEDLAKEHDKPTRK 307
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 114 bits (285), Expect = 6e-25
Identities = 84/293 (28%), Positives = 136/293 (45%), Gaps = 41/293 (13%)
Query: 93 VAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTIYEMFID---DSLYHLHIVMECM 148
VAIK + N + D R +REIK + + H+N++ + ++ ++ ++IV E M
Sbjct: 69 VAIKKIGNAFDNIIDAKRTLREIKLLKHMD-HENVIAVKDIIKPPQRENFNDVYIVYELM 127
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ +++Q++ R + + R L+Q+L G P N+L++
Sbjct: 128 DTDLHQII--RSNQPLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNA------ 179
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
N +KL D+GLAR + T YV TRWYR+PE+LL Y+ +DIW
Sbjct: 180 -----------NCDLKLGDFGLARTKSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIW 228
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSING--KEHFGGSWLDSKPLYQA 326
+ GC++ E T PLFPG D Q+ I +L+GSPD S G + ++ P Y
Sbjct: 229 SVGCILGETMTREPLFPGKDYVHQLRLITELIGSPDDSSLGFLRSDNARRYVRQLPQYPR 288
Query: 327 LNY--EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
N+ FP + + D++ L ++PS R T +E PY
Sbjct: 289 QNFAARFPNMSAGAV-------------DLLEKMLVFDPSRRITVDEALCHPY 328
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 114 bits (284), Expect = 7e-25
Identities = 78/293 (26%), Positives = 136/293 (45%), Gaps = 36/293 (12%)
Query: 112 REIKFILQIPAHKNLVTIYEMFI-----DDSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
RE++ I++I H N+V + + D +Y L++V+E M + IY+ + R+ S+
Sbjct: 72 RELQ-IMRIMKHPNIVDLIAYYYTTGDNSDEVY-LNLVLEFMPETIYRASRLYTRQKLSM 129
Query: 167 PTL--RSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
P L + ++Q+L P+N+L+ P +N ++K
Sbjct: 130 PMLEVKLYIYQLLRSLAYIHASGICHRDIKPQNLLLDP----------------ENGILK 173
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
L D+G A+ + P +Y+ +R+YR+PE++ Y+ +DIW+ GCV+ EL PLF
Sbjct: 174 LCDFGSAKILVAGEPNVSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLF 233
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG DQ+ I+ +LG+P P Y + + FP + + + V
Sbjct: 234 PGESGIDQLVEIIKILGTPSRE---------QIKTMNPNY--MEHRFPQIRPQPLSRVFS 282
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNGTAS 397
D D+++ L++ P++R TA E P+F E L + N AS
Sbjct: 283 RSVPLDALDLLSKMLQYTPTDRLTAAEAMCHPFFDELRDPNTKLHNSRNPDAS 335
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 112 bits (281), Expect = 2e-24
Identities = 89/313 (28%), Positives = 148/313 (46%), Gaps = 46/313 (14%)
Query: 87 YKKKGI-VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID---DSLYHLH 142
+K GI VAIK + L +REIK + H+N+++I + D L ++
Sbjct: 32 HKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVRPVSIDKLNAVY 91
Query: 143 IVMECMEQNIYQLMKHRKRRVFSLPT--LRSILFQILAGXXXXXXXXXXXXXXXPENILI 200
+V E ME ++ +++ ++ +L ++ +QIL P N+L+
Sbjct: 92 LVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLL 151
Query: 201 SPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSP--------YTTYVSTRWYRSP 252
+ N +K+ D+GLAR + + S T YV+TRWYR+P
Sbjct: 152 N-----------------SNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAP 194
Query: 253 EILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPD----HSIN 308
EI+L Y+ +DIW+ GC++ E+ + PLFPG D Q+W IL++LG+P + I
Sbjct: 195 EIMLTFQEYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIK 254
Query: 309 GKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERAT 368
K ++ + P+ L +E V KT D+ P D+ D++ L++NP +R +
Sbjct: 255 SKR--AKEYIANLPMRPPLPWE--TVWSKT--DLNP-----DMIDLLDKMLQFNPDKRIS 303
Query: 369 ANEICALPYFKEY 381
A E PY Y
Sbjct: 304 AAEALRHPYLAMY 316
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 112 bits (280), Expect = 2e-24
Identities = 85/294 (28%), Positives = 143/294 (47%), Gaps = 39/294 (13%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REI + + H N+V ++++ I + +L+++ E + ++ +LM +K+ VF+
Sbjct: 51 TAIREISLLKNLK-HPNVVQLFDVVISGN--NLYMIFEYLNMDLKKLMD-KKKDVFTPQL 106
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
++S + QIL P+N+L+ + + +KLAD+
Sbjct: 107 IKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGK-----------------IKLADF 149
Query: 229 GLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLAR N YT V T WYR+PEILL +YS +DIW+ GC+ E+ LFPG
Sbjct: 150 GLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGD 209
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQ 347
E DQ++RI L +PD + +W L +FP EG +P P
Sbjct: 210 SEIDQLYRIFRTLSTPDET---------NWPGVTQL-PDFKTKFPRWEGTN----MPQPI 255
Query: 348 LE-DLYDVVTSCLKWNPSERATANEICALPYFK--EYVMREASLAKTNNGTASK 398
E + ++++ S L ++P+ R +A + YF+ ++V A N G+AS+
Sbjct: 256 TEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPVDPNAGSASR 309
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 110 bits (276), Expect = 6e-24
Identities = 76/284 (26%), Positives = 129/284 (44%), Gaps = 39/284 (13%)
Query: 104 TLHDYTRVREIKFILQIPAHKNLVTIYEMFID---DSLYHLHIVMECMEQNIYQLMKHRK 160
T+ +REIK + H+N+V I ++ + DS ++IV E ME ++Y+ +K +
Sbjct: 98 TIEAKRTLREIKLLRHFD-HENIVAIRDVILPPQRDSFEDVYIVNELMEFDLYRTLKSDQ 156
Query: 161 RRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDN 220
+ ++QIL G P N+L+S
Sbjct: 157 E--LTKDHGMYFMYQILRGLKYIHSANVLHRDLKPSNLLLSTQCD--------------- 199
Query: 221 YVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATF 280
+K+ D+GLAR + T YV TRWYR+PE+LL Y+ +D+W+ GC+ +E+
Sbjct: 200 --LKICDFGLARATPESNLMTEYVVTRWYRAPELLLGSSDYTAAIDVWSVGCIFMEIMNR 257
Query: 281 SPLFPGSDETDQIWRILDLLGSP-DHSINGKEHFGGSWLDSKPLY--QALNYEFPYVEGK 337
PLFPG D+ +Q+ +L+L+G+P + + + ++ P Q+ +FP V
Sbjct: 258 EPLFPGKDQVNQLRLLLELIGTPSEEELGSLSEYAKRYIRQLPTLPRQSFTEKFPNVPPL 317
Query: 338 TIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
I D+V L ++P +R + E A PY +
Sbjct: 318 AI-------------DLVEKMLTFDPKQRISVKEALAHPYLSSF 348
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 110 bits (276), Expect = 6e-24
Identities = 69/221 (31%), Positives = 114/221 (51%), Gaps = 24/221 (10%)
Query: 93 VAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTIYEMFID---DSLYHLHIVMECM 148
VAIK + N + D R +REIK + + H+N++TI ++ D ++IV E M
Sbjct: 101 VAIKKIGNAFDNIIDAKRTLREIKLLRHMD-HENVITIKDIVRPPQRDIFNDVYIVYELM 159
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ ++ +++ R + + R +++Q+L G P N+L++ +
Sbjct: 160 DTDLQRIL--RSNQTLTSDQCRFLVYQLLRGLKYVHSANILHRDLRPSNVLLNSKNE--- 214
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+K+ D+GLAR ++ T YV TRWYR+PE+LL Y+ +DIW
Sbjct: 215 --------------LKIGDFGLARTTSDTDFMTEYVVTRWYRAPELLLNCSEYTAAIDIW 260
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSING 309
+ GC++ E+ T PLFPG D Q+ I +L+GSPD+S G
Sbjct: 261 SVGCILGEIMTGQPLFPGKDYVHQLRLITELVGSPDNSSLG 301
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 110 bits (276), Expect = 6e-24
Identities = 80/292 (27%), Positives = 135/292 (45%), Gaps = 40/292 (13%)
Query: 93 VAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTIYEMF---IDDSLYHLHIVMECM 148
VAIK + N D R +REIK + + H+N+V I ++ + ++ ++I E M
Sbjct: 89 VAIKKIANAFDNKIDAKRTLREIKLLRHMD-HENIVAIRDIIPPPLRNAFNDVYIAYELM 147
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ +++Q++ R + S + L+QIL G P N+L++
Sbjct: 148 DTDLHQII--RSNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNA------ 199
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
N +K+ D+GLAR + T YV TRWYR+PE+LL Y+ +D+W
Sbjct: 200 -----------NCDLKICDFGLARVTSESDFMTEYVVTRWYRAPELLLNSSDYTAAIDVW 248
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP-DHSINGKEHFGGSWLDSKPLY--Q 325
+ GC+ +EL PLFPG D Q+ +++L+G+P + + ++ P Y Q
Sbjct: 249 SVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEEELEFLNENAKRYIRQLPPYPRQ 308
Query: 326 ALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
++ +FP V I D++ L ++P R T + A PY
Sbjct: 309 SITDKFPTVHPLAI-------------DLIEKMLTFDPRRRITVLDALAHPY 347
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 110 bits (276), Expect = 6e-24
Identities = 85/288 (29%), Positives = 136/288 (46%), Gaps = 37/288 (12%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNI-YQLMKHRKRRVFSLPTL 169
+REI+ + + H NLV++ E+F LH+V E E + ++L +H + L
Sbjct: 49 LREIRLLKNLK-HPNLVSLLEVFRRKR--RLHLVFEFCELTVLHELERHPQGCPEHLT-- 103
Query: 170 RSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYG 229
+ I +Q L G PENIL++ + VKL D+G
Sbjct: 104 KQICYQTLLGVAYCHKQGCLHRDIKPENILLTAQGQ-----------------VKLCDFG 146
Query: 230 LARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDE 289
AR ++ YT YV+TRWYR+PE+L+ Y P+D+WA GC+ EL L+PG +
Sbjct: 147 FARMLSPGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGCLFAELVRGEALWPGRSD 206
Query: 290 TDQIWRILDLLGS--PDH-SINGK-EHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPN 345
DQ++ I LG P H I G+ E+F G L P + L + P K+ ++ L
Sbjct: 207 VDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVPPTLEPLEDKMP---AKSQQNPL-- 261
Query: 346 PQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNN 393
D + CL +P++R + ++ YF +Y+ ++ L N+
Sbjct: 262 -----TIDFLKKCLDKDPTKRWSCEKLTKHSYFDDYIAKQRELEHVNS 304
>YBL016w [T] KOG0660 Mitogen-activated protein kinase
Length = 353
Score = 110 bits (275), Expect = 8e-24
Identities = 87/310 (28%), Positives = 146/310 (47%), Gaps = 55/310 (17%)
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYH---LHIVMECM 148
IVAIK + L +REIK IL+ H+N++TI+ + DS + ++I+ E M
Sbjct: 38 IVAIKKIEPFDKPLFALRTLREIK-ILKHFKHENIITIFNIQRPDSFENFNEVYIIQELM 96
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ ++++++ ++ S ++ ++Q L P N+LI+
Sbjct: 97 QTDLHRVIS---TQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLIN------- 146
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNN-----------RSPYTTYVSTRWYRSPEILLR 257
N +K+ D+GLAR ++ +S T YV+TRWYR+PE++L
Sbjct: 147 ----------SNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLT 196
Query: 258 KGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSING----KEHF 313
YS+ +D+W+ GC++ EL P+FPG D Q+ I ++G+P HS N +
Sbjct: 197 SAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTP-HSDNDLRCIESPR 255
Query: 314 GGSWLDSKPLYQALNYE--FPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANE 371
++ S P+Y A E FP V K I D++ L ++P++R TA E
Sbjct: 256 AREYIKSLPMYPAAPLEKMFPRVNPKGI-------------DLLQRMLVFDPAKRITAKE 302
Query: 372 ICALPYFKEY 381
PY + Y
Sbjct: 303 ALEHPYLQTY 312
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 110 bits (275), Expect = 8e-24
Identities = 101/368 (27%), Positives = 168/368 (45%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETL--------MDQTLIRNVEQENW 85
+E+G+G+ S L E Y +S A ++ P+ L +D+ N +E
Sbjct: 369 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVDEFQCLNRIEEGT 428
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 429 YGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 487
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 488 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 546
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T+WYR+PE+L
Sbjct: 547 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL 589
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG+ E DQI ++ LG+P I
Sbjct: 590 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI-------- 641
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P+ + + + E PY +R E +D++ L + P R +A +
Sbjct: 642 -WPGYSELPVVKKMTFSEHPY---NNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDG 697
Query: 373 CALPYFKE 380
YF+E
Sbjct: 698 LKHEYFRE 705
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 110 bits (275), Expect = 8e-24
Identities = 101/368 (27%), Positives = 168/368 (45%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETL--------MDQTLIRNVEQENW 85
+E+G+G+ S L E Y +S A ++ P+ L +D+ N +E
Sbjct: 371 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVDEFQCLNRIEEGT 430
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 431 YGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 489
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 490 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 548
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T+WYR+PE+L
Sbjct: 549 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL 591
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG+ E DQI ++ LG+P I
Sbjct: 592 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI-------- 643
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P+ + + + E PY +R E +D++ L + P R +A +
Sbjct: 644 -WPGYSELPVVKKMTFSEHPY---NNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDG 699
Query: 373 CALPYFKE 380
YF+E
Sbjct: 700 LKHEYFRE 707
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 110 bits (275), Expect = 8e-24
Identities = 84/295 (28%), Positives = 144/295 (48%), Gaps = 32/295 (10%)
Query: 92 IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQ 150
IVA+K + M + T +REI +L+ H N+V + E+ + ++ +++ ME +E
Sbjct: 381 IVALKRLKMEKEKEGFPITALREINMLLKAGNHPNIVNVKEILLGSNMDKIYMAMEFVEH 440
Query: 151 NIYQLMK--HRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
++ L+ R+ + FS+ +++L Q+L+G N+L+S
Sbjct: 441 DMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIEHMHKLWILHRDLKTSNLLMSHKG---- 496
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
++K+AD+GLAR + +T+ V T WYRSPE+LL YS P+D+
Sbjct: 497 -------------ILKIADFGLAREYGDPLKKFTSIVVTLWYRSPELLLGTRLYSTPVDM 543
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQAL 327
W+ GC++ E PLFPG E +QI +I +G+P SI G + LD ++AL
Sbjct: 544 WSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESI----WPGVTELDG---WKAL 596
Query: 328 NYE-FPYVEGKTIRDVLPNPQLEDL-YDVVTSCLKWNPSERATANEICALPYFKE 380
+E +PY + + L L D + ++ L +P R +A + +F E
Sbjct: 597 TFEKYPY--NQLRKRFLAGRLLNDTGFKLLNGLLTLDPKNRFSATQALDHEWFTE 649
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 110 bits (274), Expect = 1e-23
Identities = 80/280 (28%), Positives = 129/280 (45%), Gaps = 41/280 (14%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHL---HIVMECMEQNIYQLMKHRKRRVFSLP 167
+REIK + H+N+++I ++ S L +IV E ME ++Y++++ + S
Sbjct: 83 LREIKLLRHF-RHENIISILDILPPPSYQELEDVYIVQELMETDLYRVIRSQP---LSDD 138
Query: 168 TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
+ +QIL P N+L++ N +K+AD
Sbjct: 139 HCQYFTYQILRALKAMHSAGVVHRDLKPSNLLLNA-----------------NCDLKVAD 181
Query: 228 YGLARHVN----NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPL 283
+GLAR N T YV+TRWYR+PEI+L YSK +D+W+ GC++ E+ + PL
Sbjct: 182 FGLARSTTAQGGNPGFMTEYVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPL 241
Query: 284 FPGSDETDQIWRILDLLGSP--DHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRD 341
FPG D QI IL++LG+P D K ++ S P ++++ + +
Sbjct: 242 FPGKDYHSQITLILNILGTPTMDDFSRIKSARARKYIKSLPFTPKVSFKALFPQAS---- 297
Query: 342 VLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
D D++ L +NP +R TA E PY Y
Sbjct: 298 -------PDAIDLLEKLLTFNPDKRITAEEALKHPYVAAY 330
>SPAC1E11.03 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 534
Score = 110 bits (274), Expect = 1e-23
Identities = 105/412 (25%), Positives = 185/412 (44%), Gaps = 76/412 (18%)
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHK-------NLVTIYEMFIDDSLYH 140
K + IVAIK + N+ P ++ V E+ IL++ +K +L+ +Y+ F+ + H
Sbjct: 151 KTQQIVAIKVIKNK-PAFYNQC-VMEVS-ILELLNNKYDPEDKRHLIRLYDQFMHKN--H 205
Query: 141 LHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILI 200
L +V E + N+Y+L+K + R L +RS Q+L+ PENIL+
Sbjct: 206 LCLVFELLSINLYELIKQNQFRGLHLSLVRSFATQLLSCTSLLKQARIIHCDLKPENILL 265
Query: 201 SPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGY 260
+ +VK+ D+G A H R TY+ +R+YRSPE++L +
Sbjct: 266 QDL---------------SSPIVKVIDFGSACH--ERQTVYTYIQSRFYRSPEVILGL-H 307
Query: 261 YSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP-----DHSINGKEHFGG 315
Y+ +D+W+ GC++ EL PLFPG+ E +Q+ RI+D+LG+P + N K+++
Sbjct: 308 YNCGIDMWSLGCILAELFLGLPLFPGNSEYNQLCRIVDMLGNPPTWMLEMGKNSKKYYNS 367
Query: 316 SWLDSKPLYQALNYE--------------------------FPYVEGKTIRDVLPNPQLE 349
+++ + Y+ + E Y KT + P E
Sbjct: 368 GFVNGRKTYELKSIEQFSIENNKTEQPGKQYFGEKTLDAIVLNYPRRKTTPKLTPEEHEE 427
Query: 350 DL--YDVVTSCLKWNPSERATANEICALPY-----FKEYVMREASLAKTNNGTASKNKDN 402
L D + L+ NP +R T ++ P+ F +Y + + T T +N+ +
Sbjct: 428 RLCFIDFIKQFLELNPLKRWTPDQAKNHPFITGASFSQYCIDKQKPLLTTQRT--RNRSH 485
Query: 403 TALANKLAANPSISNQWSRILSGLPHNPELGIVPSFNSPQKLPKVQKNNQMN 454
T + N+ PS+ R + + + PE V + PQ P +N ++
Sbjct: 486 T-IGNQAVVPPSL----QRASTYVSNEPE-EFVHTRPLPQYYPPANENENVD 531
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 110 bits (274), Expect = 1e-23
Identities = 101/368 (27%), Positives = 168/368 (45%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 371 EEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 430
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 431 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 489
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 490 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 548
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T+WYR+PE+L
Sbjct: 549 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL 591
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG+ E DQI ++ LG+P I
Sbjct: 592 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI-------- 643
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P+ + + + E PY +R + +D++ L + P R +A +
Sbjct: 644 -WPGYSELPVVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 699
Query: 373 CALPYFKE 380
YF+E
Sbjct: 700 LKHEYFRE 707
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 110 bits (274), Expect = 1e-23
Identities = 101/368 (27%), Positives = 168/368 (45%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 374 EEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 433
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 434 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 492
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 493 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 551
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T+WYR+PE+L
Sbjct: 552 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL 594
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG+ E DQI ++ LG+P I
Sbjct: 595 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI-------- 646
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P+ + + + E PY +R + +D++ L + P R +A +
Sbjct: 647 -WPGYSELPVVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 702
Query: 373 CALPYFKE 380
YF+E
Sbjct: 703 LKHEYFRE 710
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 110 bits (274), Expect = 1e-23
Identities = 101/368 (27%), Positives = 168/368 (45%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 361 EEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 420
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 421 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 479
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 480 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 538
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T+WYR+PE+L
Sbjct: 539 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL 581
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG+ E DQI ++ LG+P I
Sbjct: 582 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI-------- 633
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P+ + + + E PY +R + +D++ L + P R +A +
Sbjct: 634 -WPGYSELPVVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 689
Query: 373 CALPYFKE 380
YF+E
Sbjct: 690 LKHEYFRE 697
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 110 bits (274), Expect = 1e-23
Identities = 101/368 (27%), Positives = 168/368 (45%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 370 EEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 429
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 430 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 488
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 489 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 547
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T+WYR+PE+L
Sbjct: 548 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL 590
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG+ E DQI ++ LG+P I
Sbjct: 591 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI-------- 642
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P+ + + + E PY +R + +D++ L + P R +A +
Sbjct: 643 -WPGYSELPVVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 698
Query: 373 CALPYFKE 380
YF+E
Sbjct: 699 LKHEYFRE 706
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 109 bits (272), Expect = 2e-23
Identities = 87/283 (30%), Positives = 136/283 (47%), Gaps = 47/283 (16%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFID---DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLP 167
+REIK IL H+N++ I E+ DSL ++IV ME ++Y+L+K +K S
Sbjct: 140 LREIK-ILNRFKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQK---LSND 195
Query: 168 TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
+ L+QIL G P N+L++ + +K+ D
Sbjct: 196 HVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCD-----------------LKICD 238
Query: 228 YGLARHVNNRSPYT----TYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPL 283
+GLAR + ++ +T YV+TRWYR+PEI+L Y+K +D+W+ GC++ E+ + PL
Sbjct: 239 FGLARVTDPQTDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPL 298
Query: 284 FPGSDETDQIWRILDLLGSPDHS-----INGKEHFGGSWLDSKPLYQALNYEFPYVEGKT 338
FPG DQ+ IL ++GSP ++ IN K S+L S P + Y
Sbjct: 299 FPGKHYLDQLNLILAVVGSPSNADLQCIINDKAR---SYLISLPHKPKQPWARLYPGA-- 353
Query: 339 IRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
+P+ DL D L +NP R + A PY ++Y
Sbjct: 354 ------DPRALDLLD---KMLTFNPHNRIDIEQALAHPYLEQY 387
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 109 bits (272), Expect = 2e-23
Identities = 87/283 (30%), Positives = 136/283 (47%), Gaps = 47/283 (16%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFID---DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLP 167
+REIK IL H+N++ I E+ DSL ++IV ME ++Y+L+K +K S
Sbjct: 72 LREIK-ILNRFKHENIINIQEIIRSETVDSLKDIYIVQCLMETDLYKLLKTQK---LSND 127
Query: 168 TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
+ L+QIL G P N+L++ + +K+ D
Sbjct: 128 HVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCD-----------------LKICD 170
Query: 228 YGLARHVNNRSPYT----TYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPL 283
+GLAR + ++ +T YV+TRWYR+PEI+L Y+K +D+W+ GC++ E+ + PL
Sbjct: 171 FGLARVTDPQTDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNRPL 230
Query: 284 FPGSDETDQIWRILDLLGSPDHS-----INGKEHFGGSWLDSKPLYQALNYEFPYVEGKT 338
FPG DQ+ IL ++GSP ++ IN K S+L S P + Y
Sbjct: 231 FPGKHYLDQLNLILAVVGSPSNADLQCIINDKAR---SYLISLPHKPKQPWARLYPGA-- 285
Query: 339 IRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
+P+ DL D L +NP R + A PY ++Y
Sbjct: 286 ------DPRALDLLD---KMLTFNPHNRIDIEQALAHPYLEQY 319
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 109 bits (272), Expect = 2e-23
Identities = 81/298 (27%), Positives = 133/298 (44%), Gaps = 51/298 (17%)
Query: 93 VAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTIYEMFID---DSLYHLHIVMECM 148
+AIK + D R +REIK + + H+N+V I ++ + ++IV E M
Sbjct: 66 IAIKKIGKAFDNKVDAKRTLREIKLLRHLE-HENVVVIKDIIRPPKKEDFVDVYIVFELM 124
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ +++Q++ R + + + L+QIL G P N+L++
Sbjct: 125 DTDLHQII--RSNQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLN------- 175
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
N +K+ D+GLAR + T YV TRWYR+PE+LL Y+ +D+W
Sbjct: 176 ----------SNCDLKITDFGLARTTSETEYMTEYVVTRWYRAPELLLNSSEYTSAIDVW 225
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPD-------HSINGKEHFGGSWLDSK 321
+ GC+ E+ T PLFPG D Q+ I +L+GSPD S N ++ ++
Sbjct: 226 SVGCIFAEIMTREPLFPGKDYVHQLKLITELIGSPDGASLEFLRSANARK-----YVKEL 280
Query: 322 PLYQALNY--EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
P + N+ FP + I D++ L ++P +R T E PY
Sbjct: 281 PKFPRQNFSARFPSMNSTAI-------------DLLEKMLVFDPVKRITVEEALCYPY 325
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 108 bits (271), Expect = 2e-23
Identities = 82/281 (29%), Positives = 134/281 (47%), Gaps = 47/281 (16%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REI + ++ H N+V++ ++ + DS L+++ E + ++ K+ + S+P
Sbjct: 47 TAIREISLLKEL-RHPNIVSLQDVLMQDS--RLYLIFEFLSMDL-------KKYLDSIPP 96
Query: 169 --------LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDN 220
++S L+QIL G P+N+LI D
Sbjct: 97 GQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLID-----------------DK 139
Query: 221 YVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELAT 279
+KLAD+GLAR YT V T WYRSPE+LL YS P+DIW+ G + ELAT
Sbjct: 140 GTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELAT 199
Query: 280 FSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTI 339
PLF G E DQ++RI LG+P++ + W + + L N FP + ++
Sbjct: 200 KKPLFHGDSEIDQLFRIFRALGTPNNEV---------WPEVESLQDYKN-TFPKWKPGSL 249
Query: 340 RDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ N E+ D+++ L ++P++R + PYF +
Sbjct: 250 ASHVKNLD-ENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 108 bits (271), Expect = 2e-23
Identities = 90/366 (24%), Positives = 152/366 (40%), Gaps = 76/366 (20%)
Query: 28 NIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYY 87
+I ++++ + LGKG++G V A YD S T
Sbjct: 8 HIHEKFDLQKRLGKGAYGIVWKA---YDKRSRET-------------------------- 38
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVME 146
VA+K + + D R RE+ F+ + H N++ +Y +F D+ +++ E
Sbjct: 39 -----VALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYNIFRADNDRDIYLAFE 93
Query: 147 CMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRY 206
ME +++ ++K K + + I+ Q+ P N+L+ R
Sbjct: 94 FMEADLHNVIK--KGSILKDVHKQYIMCQLFRAIRFLHSGNVLHRDLKPSNVLLDADCR- 150
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPY---------TTYVSTRWYRSPEILLR 257
VKLAD+GLAR +++ Y T YV+TRWYRSPEILL
Sbjct: 151 ----------------VKLADFGLARSLSSLEDYPEGQKMPDLTEYVATRWYRSPEILLA 194
Query: 258 KGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHS--INGKEHFGG 315
Y+K +D+W+ GC++ E+ LFPGS +QI RI++ + P + + H+
Sbjct: 195 AKRYTKGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMNTIAKPSRADIASIGSHYAA 254
Query: 316 SWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICAL 375
S L+ P + + +T D+V L + P +R T +
Sbjct: 255 SVLEKMPQRPRKPLDLIITQSQTA-----------AIDMVQRLLIFAPQKRLTVEQCLVH 303
Query: 376 PYFKEY 381
PY ++
Sbjct: 304 PYVVQF 309
>SPAC2F7.03c [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1087
Score = 108 bits (270), Expect = 3e-23
Identities = 111/441 (25%), Positives = 183/441 (41%), Gaps = 70/441 (15%)
Query: 28 NIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYY 87
+I RY V+ LGKGSFG V +R ++ Y
Sbjct: 694 HIAYRYEVVDFLGKGSFGQV-----------------------------LRCID-----Y 719
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLY---HLHIV 144
+ +VA+K + N+ H V E K + +I L + D Y HL +
Sbjct: 720 ETGKLVALKIIRNK-KRFHMQALV-ETKILQKIREWDPLDEYCMVQYTDHFYFRDHLCVA 777
Query: 145 MECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH 204
E + +N+Y+L+K + + ++SI Q++ PENIL+ H
Sbjct: 778 TELLGKNLYELIKSNGFKGLPIVVIKSITRQLIQCLTLLNEKHVIHCDLKPENILLC--H 835
Query: 205 RYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKP 264
+ S+ VK+ D+G + YT Y+ +R+YRSPE++L GY P
Sbjct: 836 PFKSQ-------------VKVIDFG-SSCFEGECVYT-YIQSRFYRSPEVILGMGY-GTP 879
Query: 265 LDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI----NGKEHFGGSWLDS 320
+D+W+ GC++ E+ T PLFPG +E +Q+ I+++ G PDHS+ + K+ F S
Sbjct: 880 IDVWSLGCIIAEMYTGFPLFPGENEQEQLACIMEIFGPPDHSLIDKCSRKKVFFDSSGKP 939
Query: 321 KPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF- 378
+P + P+ K++ VL + L ++ CLKW+P ER T + +
Sbjct: 940 RPFVSSKGVSRRPF--SKSLHQVLQCKDVSFL-SFISDCLKWDPDERMTPQQAAQHDFLT 996
Query: 379 -KEYVMREASLAKTNNGTASKNKDNTALANKLAANPSISNQWSRILSGLPHNPELGIVPS 437
K+ V R + N + + L P N + P N +V
Sbjct: 997 GKQDVRRPNTAPARQKFARPPNIETAPIPRPLPNLPMEYNDHTLPSPKEPSNQASNLV-- 1054
Query: 438 FNSPQKLPKVQKNNQMNCVTD 458
S K P + N + ++D
Sbjct: 1055 -RSSDKFPNLLTNLDYSIISD 1074
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 108 bits (269), Expect = 4e-23
Identities = 79/280 (28%), Positives = 133/280 (47%), Gaps = 41/280 (14%)
Query: 111 VREIKFILQIPAHKNLVTIYEMF---IDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLP 167
+REIK +L+ H+N++ I ++ + + ++IV + ME ++Y+L+K + S
Sbjct: 69 LREIKILLRF-RHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH---LSND 124
Query: 168 TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
+ L+QIL G P N+L++ + +K+ D
Sbjct: 125 HICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCD-----------------LKICD 167
Query: 228 YGLARHVNNRSPYT----TYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPL 283
+GLAR + +T YV+TRWYR+PEI+L Y+K +DIW+ GC++ E+ + P+
Sbjct: 168 FGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPI 227
Query: 284 FPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNY--EFPYVEGKTIRD 341
FPG DQ+ IL +LGSP L+ +A NY P+
Sbjct: 228 FPGKHYLDQLKHILGILGSPSQED----------LNCIINLKARNYLLSLPHKNKVPWNR 277
Query: 342 VLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
+ PN + L D++ L +NP +R + A PY ++Y
Sbjct: 278 LFPNADSKAL-DLLDKMLTFNPHKRIEVEQALAHPYLEQY 316
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 108 bits (269), Expect = 4e-23
Identities = 84/298 (28%), Positives = 140/298 (46%), Gaps = 36/298 (12%)
Query: 88 KKKGIVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVME 146
K IVA+K + M + T +REI IL+ H N+VT+ E+ + ++ ++IVM
Sbjct: 61 KTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGSNMDKIYIVMN 119
Query: 147 CMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRY 206
+E ++ LM+ K+ F +++++ Q+L G N+L+S +
Sbjct: 120 YVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAG-- 176
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPL 265
++K+ D+GLAR + YT V T+WYR+PE+LL YS +
Sbjct: 177 ---------------ILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAV 221
Query: 266 DIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSW--LDSKPL 323
D+W+ GC+ EL T PLFPG+ E DQI ++ LG+P I W P+
Sbjct: 222 DMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKI---------WPGYSELPV 272
Query: 324 YQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ + + E PY +R + +D++ L + P R +A + YF+E
Sbjct: 273 VKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 327
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 107 bits (268), Expect = 5e-23
Identities = 79/280 (28%), Positives = 133/280 (47%), Gaps = 41/280 (14%)
Query: 111 VREIKFILQIPAHKNLVTIYEMF---IDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLP 167
+REIK +L+ H+N++ I ++ + + ++IV + ME ++Y+L+K + S
Sbjct: 69 LREIKILLRF-RHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH---LSND 124
Query: 168 TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
+ L+QIL G P N+L++ + +K+ D
Sbjct: 125 HICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCD-----------------LKICD 167
Query: 228 YGLARHVNNRSPYT----TYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPL 283
+GLAR + +T YV+TRWYR+PEI+L Y+K +DIW+ GC++ E+ + P+
Sbjct: 168 FGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPI 227
Query: 284 FPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNY--EFPYVEGKTIRD 341
FPG DQ+ IL +LGSP L+ +A NY P+
Sbjct: 228 FPGKHYLDQLNHILGILGSPSQED----------LNCIINLKARNYLLSLPHKNKVPWNR 277
Query: 342 VLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
+ PN + L D++ L +NP +R + A PY ++Y
Sbjct: 278 LFPNADSKAL-DLLDKMLTFNPHKRIEVEQALAHPYLEQY 316
>Hs5922004 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 107 bits (267), Expect = 7e-23
Identities = 99/426 (23%), Positives = 178/426 (41%), Gaps = 81/426 (19%)
Query: 24 IPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQE 83
+P ++ RY V++ +GKGSFG V A Y + ++ V E
Sbjct: 213 VPHDHVAYRYEVLKVIGKGSFGQVVKA----------------YDHKVHQHVALKMVRNE 256
Query: 84 NWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFI--LQIPAHKNLVTIYEMFIDDSLYHL 141
++++ EI+ + L+ N + + M +++ +
Sbjct: 257 KRFHRQAA--------------------EEIRILEHLRKQDKDNTMNVIHM-LENFTFRN 295
Query: 142 HIVM--ECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENIL 199
HI M E + N+Y+L+K K + FSLP +R IL PENIL
Sbjct: 296 HICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENIL 355
Query: 200 ISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKG 259
+ R +K+ D+G + + + R TY+ +R+YR+PE++L
Sbjct: 356 LKQQGRSG---------------IKVIDFGSSCYEHQR--VYTYIQSRFYRAPEVILG-A 397
Query: 260 YYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLD 319
Y P+D+W+ GC++ EL T PL PG DE DQ+ +++LLG P + +++
Sbjct: 398 RYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVS 457
Query: 320 SK--PLYQAL----NYEFPYVEGKTIRDVLPNPQ-----------LED--LYDVVTSCLK 360
SK P Y + + G++ R L P +D D + CL+
Sbjct: 458 SKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLE 517
Query: 361 WNPSERATANEICALPYFKEYVMREASLAKTNNGTASKNKDNTALANKLAANPSISNQWS 420
W+P+ R T + P+ + + + + KT + + ++T ++ P S+ S
Sbjct: 518 WDPAVRMTPGQALRHPWLRRRLPKPPTGEKT---SVKRITESTGAITSISKLPPPSSSAS 574
Query: 421 RILSGL 426
++ + L
Sbjct: 575 KLRTNL 580
>Hs4503427 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 528
Score = 107 bits (267), Expect = 7e-23
Identities = 99/426 (23%), Positives = 178/426 (41%), Gaps = 81/426 (19%)
Query: 24 IPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQE 83
+P ++ RY V++ +GKGSFG V A Y + ++ V E
Sbjct: 140 VPHDHVAYRYEVLKVIGKGSFGQVVKA----------------YDHKVHQHVALKMVRNE 183
Query: 84 NWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFI--LQIPAHKNLVTIYEMFIDDSLYHL 141
++++ EI+ + L+ N + + M +++ +
Sbjct: 184 KRFHRQAA--------------------EEIRILEHLRKQDKDNTMNVIHM-LENFTFRN 222
Query: 142 HIVM--ECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENIL 199
HI M E + N+Y+L+K K + FSLP +R IL PENIL
Sbjct: 223 HICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENIL 282
Query: 200 ISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKG 259
+ R +K+ D+G + + + R TY+ +R+YR+PE++L
Sbjct: 283 LKQQGRSG---------------IKVIDFGSSCYEHQR--VYTYIQSRFYRAPEVILG-A 324
Query: 260 YYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLD 319
Y P+D+W+ GC++ EL T PL PG DE DQ+ +++LLG P + +++
Sbjct: 325 RYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVS 384
Query: 320 SK--PLYQAL----NYEFPYVEGKTIRDVLPNPQ-----------LED--LYDVVTSCLK 360
SK P Y + + G++ R L P +D D + CL+
Sbjct: 385 SKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLE 444
Query: 361 WNPSERATANEICALPYFKEYVMREASLAKTNNGTASKNKDNTALANKLAANPSISNQWS 420
W+P+ R T + P+ + + + + KT + + ++T ++ P S+ S
Sbjct: 445 WDPAVRMTPGQALRHPWLRRRLPKPPTGEKT---SVKRITESTGAITSISKLPPPSSSAS 501
Query: 421 RILSGL 426
++ + L
Sbjct: 502 KLRTNL 507
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 107 bits (267), Expect = 7e-23
Identities = 101/368 (27%), Positives = 165/368 (44%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 33 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 92
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 93 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 151
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 152 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 210
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T WYR+PE+L
Sbjct: 211 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 253
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG E DQI ++ LG+P I
Sbjct: 254 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI-------- 305
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P + + + E PY +R + +D++ L + P R +A +
Sbjct: 306 -WPGYSELPAVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 361
Query: 373 CALPYFKE 380
YF+E
Sbjct: 362 LKHEYFRE 369
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 107 bits (267), Expect = 7e-23
Identities = 101/368 (27%), Positives = 165/368 (44%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 365 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 424
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 425 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 483
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 484 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 542
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T WYR+PE+L
Sbjct: 543 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 585
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG E DQI ++ LG+P I
Sbjct: 586 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI-------- 637
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P + + + E PY +R + +D++ L + P R +A +
Sbjct: 638 -WPGYSELPAVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 693
Query: 373 CALPYFKE 380
YF+E
Sbjct: 694 LKHEYFRE 701
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 107 bits (267), Expect = 7e-23
Identities = 101/368 (27%), Positives = 165/368 (44%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 374 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 433
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 434 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 492
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 493 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 551
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T WYR+PE+L
Sbjct: 552 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 594
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG E DQI ++ LG+P I
Sbjct: 595 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI-------- 646
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P + + + E PY +R + +D++ L + P R +A +
Sbjct: 647 -WPGYSELPAVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 702
Query: 373 CALPYFKE 380
YF+E
Sbjct: 703 LKHEYFRE 710
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 107 bits (267), Expect = 7e-23
Identities = 101/368 (27%), Positives = 165/368 (44%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 55 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 114
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 115 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 173
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 174 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 232
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T WYR+PE+L
Sbjct: 233 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 275
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG E DQI ++ LG+P I
Sbjct: 276 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI-------- 327
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P + + + E PY +R + +D++ L + P R +A +
Sbjct: 328 -WPGYSELPAVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 383
Query: 373 CALPYFKE 380
YF+E
Sbjct: 384 LKHEYFRE 391
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 107 bits (267), Expect = 7e-23
Identities = 101/368 (27%), Positives = 165/368 (44%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 159 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 218
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 219 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 277
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 278 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 336
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T WYR+PE+L
Sbjct: 337 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 379
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG E DQI ++ LG+P I
Sbjct: 380 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI-------- 431
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P + + + E PY +R + +D++ L + P R +A +
Sbjct: 432 -WPGYSELPAVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 487
Query: 373 CALPYFKE 380
YF+E
Sbjct: 488 LKHEYFRE 495
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 107 bits (267), Expect = 7e-23
Identities = 101/368 (27%), Positives = 165/368 (44%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 342 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 401
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 402 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 460
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 461 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 519
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T WYR+PE+L
Sbjct: 520 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 562
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG E DQI ++ LG+P I
Sbjct: 563 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI-------- 614
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P + + + E PY +R + +D++ L + P R +A +
Sbjct: 615 -WPGYSELPAVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 670
Query: 373 CALPYFKE 380
YF+E
Sbjct: 671 LKHEYFRE 678
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 107 bits (267), Expect = 7e-23
Identities = 101/368 (27%), Positives = 165/368 (44%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 331 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 390
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 391 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 449
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 450 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 508
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T WYR+PE+L
Sbjct: 509 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 551
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG E DQI ++ LG+P I
Sbjct: 552 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI-------- 603
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P + + + E PY +R + +D++ L + P R +A +
Sbjct: 604 -WPGYSELPAVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 659
Query: 373 CALPYFKE 380
YF+E
Sbjct: 660 LKHEYFRE 667
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 107 bits (267), Expect = 7e-23
Identities = 101/368 (27%), Positives = 165/368 (44%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 120 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 179
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 180 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 238
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 239 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 297
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T WYR+PE+L
Sbjct: 298 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 340
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG E DQI ++ LG+P I
Sbjct: 341 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI-------- 392
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P + + + E PY +R + +D++ L + P R +A +
Sbjct: 393 -WPGYSELPAVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 448
Query: 373 CALPYFKE 380
YF+E
Sbjct: 449 LKHEYFRE 456
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 107 bits (267), Expect = 7e-23
Identities = 101/368 (27%), Positives = 165/368 (44%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 376 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 435
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 436 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 494
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 495 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 553
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T WYR+PE+L
Sbjct: 554 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 596
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG E DQI ++ LG+P I
Sbjct: 597 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI-------- 648
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P + + + E PY +R + +D++ L + P R +A +
Sbjct: 649 -WPGYSELPAVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 704
Query: 373 CALPYFKE 380
YF+E
Sbjct: 705 LKHEYFRE 712
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 107 bits (267), Expect = 7e-23
Identities = 101/368 (27%), Positives = 165/368 (44%), Gaps = 55/368 (14%)
Query: 37 QELGKGSFGSVTLAETMYDMNSSAT---QISSMYPETLMDQTLIRNVEQ--------ENW 85
+E+G+G+ S L E Y +S A ++ P+ L R+VE+ E
Sbjct: 389 EEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGT 448
Query: 86 Y---YKKKG-----IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD 136
Y Y+ K IVA+K + M + T +REI IL+ H N+VT+ E+ +
Sbjct: 449 YGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ-HPNIVTVREIVVGS 507
Query: 137 SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
++ ++IVM +E ++ LM+ K+ F +++++ Q+L G
Sbjct: 508 NMDKIYIVMNYVEHDLKSLMETMKQP-FLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTS 566
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEIL 255
N+L+S + ++K+ D+GLAR + YT V T WYR+PE+L
Sbjct: 567 NLLLSHAG-----------------ILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELL 609
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L YS +D+W+ GC+ EL T PLFPG E DQI ++ LG+P I
Sbjct: 610 LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKI-------- 661
Query: 316 SW--LDSKPLYQALNY-EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P + + + E PY +R + +D++ L + P R +A +
Sbjct: 662 -WPGYSELPAVKKMTFSEHPY---NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG 717
Query: 373 CALPYFKE 380
YF+E
Sbjct: 718 LKHEYFRE 725
>YPR054w [T] KOG0660 Mitogen-activated protein kinase
Length = 388
Score = 106 bits (265), Expect = 1e-22
Identities = 93/370 (25%), Positives = 156/370 (42%), Gaps = 80/370 (21%)
Query: 28 NIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYY 87
+I Y +IQ LGKG++G T+ + S A +I+
Sbjct: 33 SIPGYYEIIQFLGKGAYG--TVCSVKFKGRSPAARIA----------------------- 67
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYH--LHIVM 145
+ I + N+ L +RE+KF+ HKN+V + ++ I S + L+
Sbjct: 68 ----VKKISNIFNKEILLK--RAIRELKFMNFFKGHKNIVNLIDLEIVTSSPYDGLYCYQ 121
Query: 146 ECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHR 205
E ++ ++ +++ + S ++ L+QIL G P NIL +
Sbjct: 122 ELIDYDLAKVIHSSVQ--LSEFHIKYFLYQILCGLKYIHSADVIHRDLKPGNILCTL--- 176
Query: 206 YFSKKWLEDDNYSDNYVVKLADYGLAR---------HVNNRSPYTTYVSTRWYRSPEILL 256
N +K+ D+GLAR H + T YV+TRWYR+PE+LL
Sbjct: 177 --------------NGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELLL 222
Query: 257 RKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGS 316
YSK +DIWA GC++ E P+F G D QI+ I+ +LG+PD I K +
Sbjct: 223 SNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKA 282
Query: 317 W----LDSKPLYQALNYE--FPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATAN 370
W + P+Y+ + + FP+ + I +++ S L W+ + R
Sbjct: 283 WNLGKNSNNPVYKKIPWSNIFPFASHEAI-------------NLIESLLHWDSTHRLNVE 329
Query: 371 EICALPYFKE 380
+ + P+ E
Sbjct: 330 QAISHPFLNE 339
>At5g19010 [T] KOG0660 Mitogen-activated protein kinase
Length = 567
Score = 106 bits (265), Expect = 1e-22
Identities = 96/366 (26%), Positives = 160/366 (43%), Gaps = 88/366 (24%)
Query: 31 ARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKK 90
+RY + + +GKGS+G V A YD ++
Sbjct: 23 SRYRIEEVIGKGSYGVVCSA---YDTHTGEK----------------------------- 50
Query: 91 GIVAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFIDDS---LYHLHIVME 146
VAIK + + + D TR+ REIK +L++ H ++V I + + S +++V E
Sbjct: 51 --VAIKKINDIFEHVSDATRILREIK-LLRLLRHPDIVEIKHILLPPSRREFRDIYVVFE 107
Query: 147 CMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRY 206
ME +++Q++K + + L+Q+L G P+NIL + +
Sbjct: 108 LMESDLHQVIKANDD--LTPEHYQFFLYQLLRGLKYIHTANVFHRDLKPKNILANADCK- 164
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSP----YTTYVSTRWYRSPEILLRKGYYS 262
+K+ D+GLAR N +P +T YV+TRWYR+PE+ ++S
Sbjct: 165 ----------------LKICDFGLARVAFNDTPTAIFWTDYVATRWYRAPELC--GSFFS 206
Query: 263 K---PLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK------EHF 313
K +DIW+ GC+ EL T PLFPG + Q+ + D+LG+P G+ +
Sbjct: 207 KYTPAIDIWSIGCIFAELLTGKPLFPGKNVVHQLDLMTDMLGTPSAEAIGRVRNEKARRY 266
Query: 314 GGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEIC 373
S KP+ +++FP+ + +R ++ L + P +R TA E
Sbjct: 267 LSSMRKKKPI--PFSHKFPHTDPLALR-------------LLEKMLSFEPKDRPTAEEAL 311
Query: 374 ALPYFK 379
A YFK
Sbjct: 312 ADVYFK 317
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 106 bits (264), Expect = 2e-22
Identities = 77/289 (26%), Positives = 143/289 (48%), Gaps = 41/289 (14%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRV---FS 165
T +REI + +I +H+N+V + + I+ + L++ + E ++Y++++H + +V +
Sbjct: 69 TAIREIMLLREI-SHENVVKLVNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHSLN 127
Query: 166 LPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
T++S+L+Q+L G P NIL+ + ++ +VK+
Sbjct: 128 TYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVM-------------GDAEEHGIVKI 174
Query: 226 ADYGLAR-HVNNRSPYTT--YVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSP 282
AD+GLAR + P + V T WYR+PE+LL +Y+ +D+WA GC+ EL T P
Sbjct: 175 ADFGLARIYQAPLKPLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKP 234
Query: 283 LFPGSD--------ETDQIWRILDLLGSPD----HSINGKEHFGGSWLDSKPLYQALNYE 330
LF G++ + DQ+ +I +LG P ++ H W + QA Y
Sbjct: 235 LFQGAEAKSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLPH----WQNDVQHIQAHKY- 289
Query: 331 FPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
+ + +V+ Q YD+++ L+++P +R TA++ YF+
Sbjct: 290 ----DSVGLHNVVHLNQKSPAYDLLSKMLEYDPLKRITASQALEHEYFR 334
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 106 bits (264), Expect = 2e-22
Identities = 88/314 (28%), Positives = 145/314 (46%), Gaps = 57/314 (18%)
Query: 88 KKKGIVAIKTMMNRLPTLHD-----YTRVREIKFILQIPAHKNLVTIYEMFI----DDSL 138
K K IVA+K + + + T +REI +L H +V + E+ + D+ +
Sbjct: 318 KTKEIVALKKIKMKEDRFEEEYGFPLTSLREINILLSCN-HPAIVNVKEVVVGGKNDNDV 376
Query: 139 YHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENI 198
Y +VME +E ++ +M RK FS ++ ++ Q+L G P N+
Sbjct: 377 Y---MVMEHLEHDLRGVMDRRKEP-FSTSEVKCLMMQLLDGLKYLHTNWIIHRDLKPSNL 432
Query: 199 LISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEILLR 257
L++ +K+ D+G+AR + PYT V T+WYR PE+LL
Sbjct: 433 LMNNCGE-----------------LKICDFGMARQYGSPIKPYTQMVITQWYRPPELLLG 475
Query: 258 KGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI--------NG 309
YS +D+W+ GC++ EL + PLFPG E DQ+ +I +LG+P+ +I N
Sbjct: 476 AKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAIWPGFSSFPNA 535
Query: 310 KEHFGGSWLDSKPLYQALNYEFP---YVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSER 366
K F ++P Y L +FP +V G+ + E +D++ S L +P +R
Sbjct: 536 KAKF-----PTQP-YNMLRKKFPAISFVGGQILS--------ERGFDLLNSLLTLDPEKR 581
Query: 367 ATANEICALPYFKE 380
T + +F E
Sbjct: 582 LTVEDALNHGWFHE 595
>Hs4503429 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 553
Score = 105 bits (262), Expect = 3e-22
Identities = 102/428 (23%), Positives = 174/428 (39%), Gaps = 82/428 (19%)
Query: 16 DVNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQT 75
D + ++P ++ RY V++ +GKGSFG Q++ +Y L
Sbjct: 157 DADGAYIHVPRDHLAYRYEVLKIIGKGSFG----------------QVARVYDHKLRQYV 200
Query: 76 LIRNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID 135
++ V E ++++ + R+ E N++ + E F
Sbjct: 201 ALKMVRNEKRFHRQAA---------------EEIRILEHLKKQDKTGSMNVIHMLESFTF 245
Query: 136 DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXP 195
+ H+ + E + ++Y+L+K K + FS+ +R IL P
Sbjct: 246 RN--HVCMAFELLSIDLYELIKKNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKP 303
Query: 196 ENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEIL 255
ENIL+ R +K + D+G + + TY+ +R+YR+PEI+
Sbjct: 304 ENILLKHHGRSSTK---------------VIDFGSSCFEYQK--LYTYIQSRFYRAPEII 346
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGG 315
L Y S P+DIW++ C++ EL T PLFPG DE DQ+ +++LLG P + +
Sbjct: 347 LGSRY-STPIDIWSFRCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAK 405
Query: 316 SWLDSK--PLYQALNYE----FPYVEGKTIRDVLPNPQ-----------LED--LYDVVT 356
+++SK P Y ++ + V G++ R P +D + +
Sbjct: 406 YFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGSKDWGTALKGCDDYLFIEFLK 465
Query: 357 SCLKWNPSERATANEICALPYFKEYVMREASL------------AKTNNGTASKNKDNTA 404
CL W+PS R T + P+ + V R + A G SK
Sbjct: 466 RCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVG 525
Query: 405 LANKLAAN 412
+ANKL AN
Sbjct: 526 IANKLKAN 533
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 105 bits (262), Expect = 3e-22
Identities = 68/276 (24%), Positives = 128/276 (45%), Gaps = 36/276 (13%)
Query: 112 REIKFILQIPAHKNLVTIYEMFID-----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
RE++ + ++ H N+V + F D LY L++V+E + + +Y++ +H + ++
Sbjct: 159 RELQIMRKLD-HCNIVRLRYFFYSSGEKKDELY-LNLVLEYVPETVYRVARHFTKAKLTI 216
Query: 167 PTL--RSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
P L + ++Q+ P+N+L+ P D V+K
Sbjct: 217 PILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDP----------------DTAVLK 260
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
L D+G A+ + P +Y+ +R+YR+PE++ Y+ +D+W+ GCV+ EL P+F
Sbjct: 261 LCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIF 320
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG DQ+ I+ +LG+P + P Y ++FP ++ V
Sbjct: 321 PGDSGVDQLVEIIKVLGTPTRE---------QIREMNPNY--TEFKFPQIKAHPWTKVFK 369
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ + + +S L++ PS R + E CA +F E
Sbjct: 370 SRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDE 405
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 105 bits (262), Expect = 3e-22
Identities = 85/298 (28%), Positives = 138/298 (45%), Gaps = 37/298 (12%)
Query: 92 IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQ 150
IVA+K + M++ + +REI +L++ H N+V + E+ + + L + +VM EQ
Sbjct: 35 IVALKKVRMDKEKDGIPISSLREITLLLRL-RHPNIVELKEVVVGNHLESIFLVMGYCEQ 93
Query: 151 NIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKK 210
++ L+++ FS ++ I+ Q+L G N+L++
Sbjct: 94 DLASLLENMPTP-FSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMT--------- 143
Query: 211 WLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWA 269
D VK AD+GLAR P T V T WYR+PE+LL + +D+WA
Sbjct: 144 --------DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWA 195
Query: 270 YGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI---NGKEHFGGSWLDSKPLYQA 326
GC++ EL PL PG+ E QI I+ LLG+P +I K G + K Y
Sbjct: 196 VGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNN 255
Query: 327 LNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMR 384
L ++FP++ +R ++ ++P +RATA + YFKE +R
Sbjct: 256 LKHKFPWLSEAGLR-------------LLHFLFMYDPKKRATAGDCLESSYFKEKPLR 300
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 105 bits (262), Expect = 3e-22
Identities = 68/276 (24%), Positives = 128/276 (45%), Gaps = 36/276 (13%)
Query: 112 REIKFILQIPAHKNLVTIYEMFID-----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
RE++ + ++ H N+V + F D LY L++V+E + + +Y++ +H + ++
Sbjct: 159 RELQIMRKLD-HCNIVRLRYFFYSSGEKKDELY-LNLVLEYVPETVYRVARHFTKAKLTI 216
Query: 167 PTL--RSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
P L + ++Q+ P+N+L+ P D V+K
Sbjct: 217 PILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDP----------------DTAVLK 260
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
L D+G A+ + P +Y+ +R+YR+PE++ Y+ +D+W+ GCV+ EL P+F
Sbjct: 261 LCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIF 320
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG DQ+ I+ +LG+P + P Y ++FP ++ V
Sbjct: 321 PGDSGVDQLVEIIKVLGTPTRE---------QIREMNPNY--TEFKFPQIKAHPWTKVFK 369
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ + + +S L++ PS R + E CA +F E
Sbjct: 370 SRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFFDE 405
>YMR139w [G] KOG0658 Glycogen synthase kinase-3
Length = 370
Score = 105 bits (261), Expect = 3e-22
Identities = 70/284 (24%), Positives = 133/284 (46%), Gaps = 37/284 (13%)
Query: 112 REIKFILQIPAHKNLVTI----YEMFIDDSLYHLHIVMECMEQNIYQLMKH--RKRRVFS 165
RE++ I+++ +H N++ + YE D +Y L++++E M Q++YQ ++H +R S
Sbjct: 79 RELE-IMKMLSHINIIDLKYFFYERDSQDEIY-LNLILEYMPQSLYQRLRHFVHQRTPMS 136
Query: 166 LPTLRSILFQILAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
++ +FQ+ P+N+L+ P + + +K
Sbjct: 137 RLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDP----------------ETWSLK 180
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
L D+G A+ + P +Y+ +R+YR+PE++ Y+ +DIW+ GCV+ EL P+F
Sbjct: 181 LCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMF 240
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG DQ+ I+ +LG+P P Y + ++FP ++ + V
Sbjct: 241 PGESGIDQLVEIIKILGTPSKQ---------EICSMNPNY--MEHKFPQIKPIPLSRVFK 289
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASL 388
+ + + LK++P ER A + PYF E + + +
Sbjct: 290 KED-DQTVEFLADVLKYDPLERFNALQCLCSPYFDELKLDDGKI 332
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 105 bits (261), Expect = 3e-22
Identities = 102/377 (27%), Positives = 157/377 (41%), Gaps = 73/377 (19%)
Query: 6 LTTADSFIPPDVNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISS 65
+TT + FI + F I RYN + +G G+FG V SAT +
Sbjct: 1 MTTNEEFIRTQIFGTVF-----EITNRYNDLNPVGMGAFGLVC----------SATDTLT 45
Query: 66 MYPETLMDQTLIRNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRV-REIKFILQIPAHK 124
P VAIK +M T R RE+K + + H+
Sbjct: 46 SQP------------------------VAIKKIMKPFSTAVLAKRTYRELKLLKHL-RHE 80
Query: 125 NLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXX 184
NL+ + ++F+ L ++ V E ++++L++ R ++ L+QIL G
Sbjct: 81 NLICLQDIFLSP-LEDIYFVTELQGTDLHRLLQTRP---LEKQFVQYFLYQILRGLKYVH 136
Query: 185 XXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYV 244
P NILI+ +N +K+ D+GLAR + + T YV
Sbjct: 137 SAGVIHRDLKPSNILIN-----------------ENCDLKICDFGLARIQDPQM--TGYV 177
Query: 245 STRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPD 304
STR+YR+PEI+L Y +DIW+ GC+ E+ PLFPG D Q I DLLGSP
Sbjct: 178 STRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPP 237
Query: 305 HSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPS 364
+ ++ +L + P + + V P D D++ L ++P
Sbjct: 238 KDVINTI----CSENTLKFVTSLPHRDPIPFSERFKTVEP-----DAVDLLEKMLVFDPK 288
Query: 365 ERATANEICALPYFKEY 381
+R TA + A PY Y
Sbjct: 289 KRITAADALAHPYSAPY 305
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 105 bits (261), Expect = 3e-22
Identities = 75/284 (26%), Positives = 133/284 (46%), Gaps = 38/284 (13%)
Query: 104 TLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLY----HLHIVMECMEQNIYQLMKHR 159
TLH RV I++ +H N++ + F + HL +++E M + ++ M+
Sbjct: 28 TLH---RVNRELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWY 84
Query: 160 KRRVFSLPTLRSIL--FQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNY 217
RR S+P L L FQ+ P+N+L+ +Y
Sbjct: 85 TRRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLV---------------DY 129
Query: 218 SDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVEL 277
++KL D+G A+ + P +Y+ +R+YR+PE++ +Y+ +D+W+ CV+ EL
Sbjct: 130 KTG-ILKLCDFGSAKVLVPSEPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAEL 188
Query: 278 ATFSPLFPGSDETDQIWRILDLLGSPD-HSINGKEHFGGSWLDSKPLYQALNYEFPYVEG 336
PLFPG +Q+ I+ +LG+P H I+ P Y +N+ P V
Sbjct: 189 FIGRPLFPGDSSVEQLVEIIRVLGTPSYHEIS----------VMNPNY--VNHSLPNVRP 236
Query: 337 KTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
T+ V+P+ ++ D++ L + PS+R +A E+ P+F E
Sbjct: 237 HTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIEVLTHPFFDE 280
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 105 bits (261), Expect = 3e-22
Identities = 90/358 (25%), Positives = 163/358 (45%), Gaps = 72/358 (20%)
Query: 30 DARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKK 89
D +Y + E+G+G++G V A R+++ +
Sbjct: 10 DQQYECVAEIGEGAYGKVFKA---------------------------RDLKNGGRFVAL 42
Query: 90 KGIVAIKTMMNRLPTLHDYTRVREIKFI--LQIPAHKNLVTIYEMFI---DDSLYHLHIV 144
K V ++T +P + +RE+ + L+ H N+V ++++ D L +V
Sbjct: 43 KR-VRVQTGEEGMPL----STIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLV 97
Query: 145 MECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH 204
E ++Q++ + T++ ++FQ+L G P+NIL++ S
Sbjct: 98 FEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSG 157
Query: 205 RYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKP 264
+ +KLAD+GLAR + + T+ V T WYR+PE+LL+ Y + P
Sbjct: 158 Q-----------------IKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSY-ATP 199
Query: 265 LDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPL- 323
+D+W+ GC+ E+ PLF GS + DQ+ +ILD++G P G+E W L
Sbjct: 200 VDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLP-----GEE----DWPRDVALP 250
Query: 324 YQALNYEFPYVEGKTIRDVLPNPQLEDL-YDVVTSCLKWNPSERATANEICALPYFKE 380
QA + + K + D+ ++L D++ CL +NP++R +A + PYF++
Sbjct: 251 RQAFHSKSAQPIEKFVTDI------DELGKDLLLKCLTFNPAKRISAYSALSHPYFQD 302
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 105 bits (261), Expect = 3e-22
Identities = 76/290 (26%), Positives = 137/290 (47%), Gaps = 39/290 (13%)
Query: 112 REIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLP 167
RE++ ++++ H N+V + F D L+ L++VME + +++Y+++KH +P
Sbjct: 80 RELQ-LMRVMDHPNVVCLKHCFFSTTSKDELF-LNLVMEYVPESLYRVLKHYSSANQRMP 137
Query: 168 TL--RSILFQILAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
+ + ++QI G P+N+L+ P + VK
Sbjct: 138 LVYVKLYMYQIFRGLAYIHNVAGVCHRDLKPQNLLVDPL----------------THQVK 181
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
+ D+G A+ + +Y+ +R+YR+PE++ Y+ +DIW+ GCV+ EL PLF
Sbjct: 182 ICDFGSAKQLVKGEANISYICSRFYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLF 241
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG + DQ+ I+ +LG+P P Y ++ FP ++ +
Sbjct: 242 PGENAVDQLVEIIKVLGTPTRE---------EIRCMNPHY--TDFRFPQIKAHPWHKIFH 290
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNG 394
+ D + L+++PS R TA E CA P+F E +RE + A+ NG
Sbjct: 291 KRMPPEAIDFASRLLQYSPSLRCTALEACAHPFFDE--LREPN-ARLPNG 337
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 105 bits (261), Expect = 3e-22
Identities = 75/279 (26%), Positives = 130/279 (45%), Gaps = 38/279 (13%)
Query: 123 HKNLVTIYEMFID----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT--LRSILFQI 176
H N++++ F D L+ L++VME + + +Y++++H +P ++ +QI
Sbjct: 120 HPNVISLKHCFFSTTSRDELF-LNLVMEYVPETLYRVLRHYTSSNQRMPIFYVKLYTYQI 178
Query: 177 LAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVN 235
G P+N+L+ P + VKL D+G A+ +
Sbjct: 179 FRGLAYIHTVPGVCHRDVKPQNLLVDPL----------------THQVKLCDFGSAKVLV 222
Query: 236 NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWR 295
P +Y+ +R+YR+PE++ Y+ +DIW+ GCV+ EL PLFPG + DQ+
Sbjct: 223 KGEPNISYICSRYYRAPELIFGATEYTASIDIWSAGCVLAELLLGQPLFPGENSVDQLVE 282
Query: 296 ILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVV 355
I+ +LG+P P Y ++ FP ++ V + D+
Sbjct: 283 IIKVLGTPTRE---------EIRCMNPNY--TDFRFPQIKAHPWHKVFHKRMPPEAIDLA 331
Query: 356 TSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNG 394
+ L+++PS R TA E CA P+F E +RE + A+ NG
Sbjct: 332 SRLLQYSPSLRCTALEACAHPFFNE--LREPN-ARLPNG 367
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 104 bits (260), Expect = 4e-22
Identities = 84/294 (28%), Positives = 131/294 (43%), Gaps = 31/294 (10%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD----SLYHLHIVMECM 148
VAIK M R +L H N++ + F D S +++VME M
Sbjct: 55 VAIKKMQQPFLLTMSARRAYREFILLTTLKHPNIIRLLNAFTPDTSLSSFQEVYLVMEFM 114
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
N+++++ HR R TL +++Q L P NI+++
Sbjct: 115 THNLHEVI-HRLR--LDHETLSFLVYQSLCAIKHLHNLGFIHRDLKPSNIVVN------- 164
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ V+K+ D+GLAR N + YV TR+YR+PE++L Y S+ +DIW
Sbjct: 165 ----------ERCVLKVLDFGLARRRNVDMRMSDYVGTRYYRAPEVILGLNY-SEKVDIW 213
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP-DHSINGKEHFGGSWLDSKPLYQAL 327
+ GC++ E+ + LFPG D DQ +I +L +P DH IN E G ++ S P + A
Sbjct: 214 SVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTPDDHFINQLEPIGAVYVRSLPQHLAR 273
Query: 328 NYEFPYVEGKTIRDVLPNPQ----LEDLYDVVTSCLKWNPSERATANEICALPY 377
+ V NP+ L D++ + LK NP ER + + PY
Sbjct: 274 AFN-EIVPDSNFLPETENPKDHLTLHMARDLLFNMLKINPEERYSVEDALNHPY 326
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 104 bits (259), Expect = 6e-22
Identities = 86/360 (23%), Positives = 153/360 (41%), Gaps = 74/360 (20%)
Query: 29 IDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYK 88
++ + V++ELG+G++G V A + + A I I NV ++ K
Sbjct: 17 VEPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKK-----------ITNVFSKSILTK 65
Query: 89 KKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD--SLYHLHIVME 146
+ +REIK ++ H+N+ IY++ I + + ++I E
Sbjct: 66 RA--------------------LREIKLLIHFRNHRNITCIYDLDIINPYNFNEVYIYEE 105
Query: 147 CMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRY 206
ME ++ ++K + + +S ++QIL G P N+L++
Sbjct: 106 LMEADLNAIIK--SGQPLTDAHFQSFIYQILCGLKYIHSANVIHRDLKPGNLLVNADCE- 162
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVN-----NRSPYTTYVSTRWYRSPEILLRKGYY 261
+K+ D+GLAR + N T YV+TRWYR+PEI+L Y
Sbjct: 163 ----------------LKICDFGLARGCSENPEENPGFMTEYVATRWYRAPEIMLSFSSY 206
Query: 262 SKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGS----W 317
K +D+W+ GC++ EL +PLF G D Q+ IL LG+PD H S +
Sbjct: 207 HKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEET--LSHISSSRAQEY 264
Query: 318 LDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
+ S P + + +E + + + D++ L ++P+ R + ++ PY
Sbjct: 265 VRSLPKQRPIPFETNFPKANPL-----------ALDLLAKLLAFDPNRRISVDDALEHPY 313
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 104 bits (259), Expect = 6e-22
Identities = 84/294 (28%), Positives = 136/294 (45%), Gaps = 37/294 (12%)
Query: 92 IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQ 150
IVA+K + M++ + +REI +L++ H N+V + E+ + + L + +VM EQ
Sbjct: 64 IVALKKVRMDKEKDGIPISSLREITLLLRL-RHPNIVELKEVVVGNHLESIFLVMGYCEQ 122
Query: 151 NIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKK 210
++ L+++ FS ++ I+ Q+L G N+L++
Sbjct: 123 DLASLLENMPTP-FSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMT--------- 172
Query: 211 WLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWA 269
D VK AD+GLAR P T V T WYR+PE+LL + +D+WA
Sbjct: 173 --------DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWA 224
Query: 270 YGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI---NGKEHFGGSWLDSKPLYQA 326
GC++ EL PL PG+ E QI I+ LLG+P +I K G + K Y
Sbjct: 225 VGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNN 284
Query: 327 LNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
L ++FP++ +R ++ ++P +RATA + YFKE
Sbjct: 285 LKHKFPWLSEAGLR-------------LLHFLFMYDPKKRATAGDCLESSYFKE 325
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 104 bits (259), Expect = 6e-22
Identities = 86/366 (23%), Positives = 161/366 (43%), Gaps = 69/366 (18%)
Query: 33 YNVIQELGKGSFGSVTLAETMYDMNSSAT-QISSMYPETLMDQTLIRNVEQENWYYKKKG 91
+ + Q LGKG++G+V +++D A QI + Q+++R +
Sbjct: 38 FQIHQALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREI----------- 86
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMF--IDD--SLYHLHIVMEC 147
T+M L AH N++++ +F +D ++ ++++ME
Sbjct: 87 -----TVMKHLAR----------------KAHPNIISLKSVFHQLDPVRAILKINMIMER 125
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
+ +++ +++ R V + + QI+ P+NIL++
Sbjct: 126 CDWDLHTFLRNIPRGVPEQQA-KHVTAQIVRALDFLHTHSIIHRDLKPQNILLNRDQ--- 181
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
VKLAD+GL++ +N + +TT V T WYRSPE+LL + YY+ +D+
Sbjct: 182 --------------TVKLADFGLSKEYSNTTAFTTLVVTLWYRSPEVLL-QSYYNSTVDM 226
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQAL 327
WA GC+V E+ PLF G +E +Q+ I +G+P G W + +
Sbjct: 227 WALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTP---------VGKDWPSESVIARD- 276
Query: 328 NYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREAS 387
FP ++D+ P + + + V CL+++ S+R +A + P+ K V ++
Sbjct: 277 --SFPQYRPTNLKDLSPQMSKQAI-EFVQQCLRYDHSKRLSARGALSHPFLKPAVATKSR 333
Query: 388 LAKTNN 393
+ K N
Sbjct: 334 VLKQIN 339
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 103 bits (258), Expect = 7e-22
Identities = 72/276 (26%), Positives = 132/276 (47%), Gaps = 36/276 (13%)
Query: 112 REIKFILQIPAHKNLVTIYEMFIDDSLY----HLHIVMECMEQNIYQLMKHRKRRVFSLP 167
RE++ I++ +H N++ + F + HL +++E M + ++ M+ RR S+P
Sbjct: 65 RELQ-IMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIP 123
Query: 168 TLRSIL--FQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
L L FQ+ P+N+L+ +Y ++KL
Sbjct: 124 NLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLV---------------DYKTG-ILKL 167
Query: 226 ADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFP 285
D+G A+ + P +Y+ +R+YR+PE++ +Y+ +D+W+ CV+ EL PLFP
Sbjct: 168 CDFGSAKVLVPSEPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFP 227
Query: 286 GSDETDQIWRILDLLGSPD-HSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
G +Q+ I+ +LG+P H I+ P Y +N+ P V T+ V+P
Sbjct: 228 GDSSVEQLVEIIRVLGTPSYHEIS----------VMNPNY--VNHSLPNVRPHTLESVMP 275
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ ++ D++ L + PS+R +A E+ P+F E
Sbjct: 276 HNCTKNAMDLLHKMLTYVPSKRISAIEVLTHPFFDE 311
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 103 bits (258), Expect = 7e-22
Identities = 75/316 (23%), Positives = 145/316 (45%), Gaps = 48/316 (15%)
Query: 112 REIKFILQIPAHKNLVTIYEMFID-----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
RE++ + ++ H N+V + F D +Y L++V++ + + +Y++ +H R +L
Sbjct: 96 RELQIMRKLD-HCNIVRLRYFFYSSGEKKDEVY-LNLVLDYVPETVYRVARHYSRAKQTL 153
Query: 167 PTL--RSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
P + + ++Q+ P+N+L+ P D V+K
Sbjct: 154 PVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDP----------------DTAVLK 197
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
L D+G A+ + P +Y+ +R+YR+PE++ Y+ +D+W+ GCV+ EL P+F
Sbjct: 198 LCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIF 257
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG DQ+ I+ +LG+P + P Y ++FP ++ V
Sbjct: 258 PGDSGVDQLVEIIKVLGTPTRE---------QIREMNPNY--TEFKFPQIKAHPWTKVFR 306
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNGTASKNKDNTA 404
+ + + L++ P+ R T E CA +F E +R+ ++ N +D A
Sbjct: 307 PRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDE--LRDPNVKHPN------GRDTPA 358
Query: 405 LAN----KLAANPSIS 416
L N +L++NP ++
Sbjct: 359 LFNFTTQELSSNPPLA 374
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 103 bits (258), Expect = 7e-22
Identities = 77/290 (26%), Positives = 136/290 (46%), Gaps = 39/290 (13%)
Query: 112 REIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLP 167
RE++ ++++ H N+V++ F D L+ L++VME + + +Y+++KH +P
Sbjct: 112 RELQ-LMRLMDHPNVVSLKHCFFSTTTRDELF-LNLVMEYVPETLYRVLKHYTSSNQRMP 169
Query: 168 T--LRSILFQILAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
++ +QI G P+N+L+ P + K
Sbjct: 170 IFYVKLYTYQIFRGLAYIHTAPGVCHRDVKPQNLLVDPL----------------THQCK 213
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
L D+G A+ + +Y+ +R+YR+PE++ Y+ +DIW+ GCV+ EL PLF
Sbjct: 214 LCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTSSIDIWSAGCVLAELLLGQPLF 273
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG + DQ+ I+ +LG+P P Y ++ FP ++ V
Sbjct: 274 PGENSVDQLVEIIKVLGTPTRE---------EIRCMNPNY--TDFRFPQIKAHPWHKVFH 322
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNG 394
+ D+ + L+++PS R TA E CA P+F E +RE + A+ NG
Sbjct: 323 KRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNE--LREPN-ARLPNG 369
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 103 bits (257), Expect = 1e-21
Identities = 86/364 (23%), Positives = 160/364 (43%), Gaps = 69/364 (18%)
Query: 35 VIQELGKGSFGSVTLAETMYDMNSSAT-QISSMYPETLMDQTLIRNVEQENWYYKKKGIV 93
+ Q LGKG++G+V +++D A QI + Q+++R +
Sbjct: 104 LFQALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREI------------- 150
Query: 94 AIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMF--IDD--SLYHLHIVMECME 149
T+M L AH N++++ +F +D ++ ++++ME +
Sbjct: 151 ---TVMKHLAR----------------KAHPNIISLKSVFHQLDPVRAILKINMIMERCD 191
Query: 150 QNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSK 209
+++ +++ R V + + QI+ P+NIL++
Sbjct: 192 WDLHTFLRNIPRGVPEQQA-KHVTAQIVRALDFLHTHSIIHRDLKPQNILLNRDQ----- 245
Query: 210 KWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWA 269
VKLAD+GL++ +N + +TT V T WYRSPE+LL + YY+ +D+WA
Sbjct: 246 ------------TVKLADFGLSKEYSNTTAFTTLVVTLWYRSPEVLL-QSYYNSTVDMWA 292
Query: 270 YGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNY 329
GC+V E+ PLF G +E +Q+ I +G+P G W + +
Sbjct: 293 LGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTP---------VGKDWPSESVIARD--- 340
Query: 330 EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLA 389
FP ++D+ P + + + V CL+++ S+R +A + P+ K V ++ +
Sbjct: 341 SFPQYRPTNLKDLSPQMSKQAI-EFVQQCLRYDHSKRLSARGALSHPFLKPAVATKSRVL 399
Query: 390 KTNN 393
K N
Sbjct: 400 KQIN 403
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 103 bits (257), Expect = 1e-21
Identities = 83/289 (28%), Positives = 141/289 (48%), Gaps = 49/289 (16%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYH--------------LHIVMECMEQNIYQ 154
T +REI I + H N+VT++++ + L++V E +++++
Sbjct: 88 TCLREISCIKDLQ-HDNIVTLFDIIYASHFLNYNNIFFEKFSSNSKLYMVFEFIDRDLKN 146
Query: 155 LMKHRKRRVFSLPT--LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWL 212
L++ + LP ++S ++Q+L+ P+NIL+S
Sbjct: 147 LLEMLEPTNSVLPPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVS----------- 195
Query: 213 EDDNYSDNYVVKLADYGLARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYG 271
D+ V+K+AD+GLAR+ + S YT V T WYR PEILL YS LD+W+ G
Sbjct: 196 ------DSGVIKIADFGLARNFSFPSRNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLG 249
Query: 272 CVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSW--LDSKPLYQALNY 329
C+ E+A+ PLFPG E Q+++I +++G+P+ SW +DS P Y+A+
Sbjct: 250 CIFSEIASNKPLFPGECEISQLFKIFEIVGTPNIK---------SWPGVDSFPHYKAVFP 300
Query: 330 EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
++P V K + + + + DV+ L++ P R TA + YF
Sbjct: 301 QWP-VNLKKLEET--SCLTGNGLDVLREILRYPPERRLTAKGALSHRYF 346
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 103 bits (257), Expect = 1e-21
Identities = 78/275 (28%), Positives = 133/275 (48%), Gaps = 35/275 (12%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REI + ++ H N+V ++ + L++V E ++ ++ + M L
Sbjct: 47 TAIREISLLKEMQ-HSNIVKYDDVVHSEK--RLYLVFEYLDLDLKKHMDSTPDFSKDLHM 103
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
+++ L+QIL G P+N+LI D +++ +KLAD+
Sbjct: 104 IKTYLYQILRGIAYCHSHRVLHRDLKPQNLLI--------------DRRTNS--LKLADF 147
Query: 229 GLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLAR +T V T WYR+PEILL +YS P+DIW+ GC+ E+ + PLFPG
Sbjct: 148 GLARAFGIPVRTFTHEVVTLWYRAPEILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGD 207
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSW--LDSKPLYQALNYEFPYVEGKTIRDVLPN 345
E DQ+++I ++G+P + +W + S P Y++ FP + + +PN
Sbjct: 208 SEIDQLFKIFRIMGTP---------YEDTWRGVTSLPDYKS---AFPKWKPTDLETFVPN 255
Query: 346 PQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
D D+++ L +P++R A YFK+
Sbjct: 256 LD-PDGVDLLSKMLLMDPTKRINARAALEHEYFKD 289
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 103 bits (257), Expect = 1e-21
Identities = 66/225 (29%), Positives = 109/225 (48%), Gaps = 24/225 (10%)
Query: 92 IVAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTIYEMF---IDDSLYHLHIVMEC 147
+VA+K + N D R +REIK + + H+N++ I ++ + ++I E
Sbjct: 63 LVAMKKIANAFDNHMDAKRTLREIKLLRHLD-HENIIAIRDVVPPPLRRQFSDVYISTEL 121
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
M+ +++Q++ R + S + L+Q+L G P N+L++
Sbjct: 122 MDTDLHQII--RSNQSLSEEHCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNA----- 174
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
N +K+ D+GLAR + T YV TRWYR+PE+LL Y+ +D+
Sbjct: 175 ------------NCDLKICDFGLARPTSENDFMTEYVVTRWYRAPELLLNSSDYTAAIDV 222
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEH 312
W+ GC+ +EL PLFPG D Q+ + +LLG+P S G H
Sbjct: 223 WSVGCIFMELMNRKPLFPGKDHVHQMRLLTELLGTPTESDLGFTH 267
>7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 952
Score = 103 bits (257), Expect = 1e-21
Identities = 81/293 (27%), Positives = 133/293 (44%), Gaps = 26/293 (8%)
Query: 92 IVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQ 150
IVA+K + M + T +REI +L+ H N+VT+ E+ + ++ + IVM+ +E
Sbjct: 583 IVALKRLKMEKEKEGFPITSLREINTLLK-GQHPNIVTVREIVVGSNMDKIFIVMDYVEH 641
Query: 151 NIYQLMKHRKRRVFSL--PTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
++ LM+ K R S ++ + Q+L N+L+S
Sbjct: 642 DLKSLMETMKNRKQSFFPGEVKCLTQQLLRAVAHLHDNWILHRDLKTSNLLLSHKG---- 697
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
++K+ D+GLAR + YT+ V T WYR+PE+LL YS P+D+
Sbjct: 698 -------------ILKVGDFGLAREYGSPIKKYTSLVVTLWYRAPELLLCSPVYSTPIDV 744
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQAL 327
W+ GC+ E PLFPG E D++ RI LG+P N K G + L + +
Sbjct: 745 WSVGCIFAEFLQMLPLFPGKSEIDELNRIFKELGTP----NEKIWPGYTELPAVKNMLSQ 800
Query: 328 NYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
N +F +R E ++ L ++P +R +A+ +FKE
Sbjct: 801 NSQFTEYPVSQLRKHFQEKTSEMGLSLLQGLLTYDPKQRLSADAALKHGFFKE 853
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 103 bits (256), Expect = 1e-21
Identities = 90/361 (24%), Positives = 160/361 (43%), Gaps = 76/361 (21%)
Query: 26 LKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSAT--QISSMYPE------TLMDQTLI 77
L ID +Y I+ +G+G++G V + D N +I ++Y TL + L+
Sbjct: 25 LFEIDTKYMPIKPIGRGAYG-VVCSSVNSDTNEKVAIKKIHNVYENRIDALRTLRELKLL 83
Query: 78 RNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDS 137
R++ EN ++A+K +M +P HK S
Sbjct: 84 RHLRHEN-------VIALKDVM--------------------MPIHKM-----------S 105
Query: 138 LYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPEN 197
+++V E M+ +++Q++K +V S + LFQ+L G P N
Sbjct: 106 FKDVYLVYELMDTDLHQIIK--SSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGN 163
Query: 198 ILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTT-YVSTRWYRSPEILL 256
+L++ N +K+ D+GLAR N + + T YV TRWYR+PE+LL
Sbjct: 164 LLVNA-----------------NCDLKICDFGLARASNTKGQFMTEYVVTRWYRAPELLL 206
Query: 257 RKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGS 316
Y +D+W+ GC+ EL P+F G++ +Q+ I+++LGS +
Sbjct: 207 CCDNYGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGS-------QREEDLE 259
Query: 317 WLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALP 376
++D+ P + PY G ++ + P + + D++ L ++PS+R + +E P
Sbjct: 260 FIDN-PKAKRYIRSLPYSPGMSLSRLYPGAHVLAI-DLLQKMLVFDPSKRISVSEALQHP 317
Query: 377 Y 377
Y
Sbjct: 318 Y 318
>CE04430 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 821
Score = 102 bits (255), Expect = 2e-21
Identities = 79/276 (28%), Positives = 123/276 (43%), Gaps = 49/276 (17%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
+Y V++ LGKG+FG V A A +I +P Y ++G
Sbjct: 121 QYEVLEFLGKGTFGQVVKAWKKGTSEIVAIKILKKHPS-----------------YARQG 163
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
+ + ++++RL + N V +E F S H +V E +EQN
Sbjct: 164 QIEV-SILSRLSN--------------ENSEEFNFVRAFECFNHKS--HTCLVFEMLEQN 206
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+Y +K K L +R ILFQ+L PENI++
Sbjct: 207 LYDFLKQNKFMPLPLNAIRPILFQVLTALLKLKSLGLIHADLKPENIMLV---------- 256
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYG 271
D Y VK+ D+G A H +++ TY+ +R+YR+PEI+L +++ +D+W+ G
Sbjct: 257 ---DPQQQPYRVKVIDFGSASH-RSKAVTNTYLQSRYYRAPEIILGLP-FNESIDMWSLG 311
Query: 272 CVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI 307
CV+ EL PL+PGS E DQI I+ G P S+
Sbjct: 312 CVIAELFLGWPLYPGSSEYDQIRFIIQTQGLPPTSM 347
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 102 bits (255), Expect = 2e-21
Identities = 80/290 (27%), Positives = 139/290 (47%), Gaps = 34/290 (11%)
Query: 93 VAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTIYEMFIDD---SLYHLHIVMECM 148
VAIK + N D R +RE+K + + H+N+V + ++ + + S +++V E M
Sbjct: 58 VAIKKIHNVFENRIDALRTLRELKLLRHL-RHENVVALKDVMMANHKRSFKDVYLVYELM 116
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ +++Q++K +V S + LFQ+L G P N+L++
Sbjct: 117 DTDLHQIIK--SSQVLSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNA------ 168
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTT-YVSTRWYRSPEILLRKGYYSKPLDI 267
N +K+ D+GLAR N + + T YV TRWYR+PE+LL Y +D+
Sbjct: 169 -----------NCDLKICDFGLARTSNTKGQFMTEYVVTRWYRAPELLLCCDNYGTSIDV 217
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQAL 327
W+ GC+ EL P+FPG++ +QI I+++LGS + ++D+ P +
Sbjct: 218 WSVGCIFAELLGRKPVFPGTECLNQIKLIINILGS-------QREEDLEFIDN-PKAKRY 269
Query: 328 NYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
PY G + + P + + D++ L +PS+R + E PY
Sbjct: 270 IESLPYSPGISFSRLYPGANVLAI-DLLQKMLVLDPSKRISVTEALQHPY 318
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 102 bits (255), Expect = 2e-21
Identities = 86/367 (23%), Positives = 156/367 (42%), Gaps = 68/367 (18%)
Query: 112 REIKFILQIPAHKNLVTIYEMFID-----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
RE++ + ++ H N+V + F D ++ L++V+E + + +Y++ + + ++
Sbjct: 588 RELQIMRKLE-HCNIVKLLYFFYSSGEKRDEVF-LNLVLEYIPETVYKVARQYAKTKQTI 645
Query: 167 PT--LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
P +R ++Q+ P+N+L+ P + V+K
Sbjct: 646 PINFIRLYMYQLFRSLAYIHSLGICHRDIKPQNLLLDP----------------ETAVLK 689
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
L D+G A+ + + P +Y+ +R+YR+PE++ Y+ +D+W+ GCV+ EL P+F
Sbjct: 690 LCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIF 749
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG DQ+ ++ +LG+P + P Y ++FP ++ + V
Sbjct: 750 PGDSGVDQLVEVIKVLGTPTRE---------QIREMNPNY--TEFKFPQIKSHPWQKVFR 798
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNGTASKNKDNTA 404
+ ++V+ L++ PS R T + CA P+F E L N T +D
Sbjct: 799 IRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDE-------LRMEGNHTLPNGRDMPP 851
Query: 405 LANKLAANPSISNQWSRILSGLPHNPELGIVPSFNSPQKLPKVQKNNQMNCVTDKSQQQP 464
L N EL I PS PQ LPK +N + +P
Sbjct: 852 LFNFT-------------------EHELSIQPSL-VPQLLPKHLQN-----ASGPGGNRP 886
Query: 465 RRGGVAS 471
GG AS
Sbjct: 887 SAGGAAS 893
>CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 463
Score = 102 bits (254), Expect = 2e-21
Identities = 82/295 (27%), Positives = 134/295 (44%), Gaps = 36/295 (12%)
Query: 93 VAIKTMMNRLPTL-HDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMEC 147
VAIK + + H RE+K ++ + HKN++ I F D L+IVME
Sbjct: 145 VAIKKLSRPFQNVTHAKRAYRELK-LMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMEL 203
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
M+ N+ Q+++ L +L+Q+L G P NI++
Sbjct: 204 MDANLCQVIQMD----LDHERLSYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVR------ 253
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +D+
Sbjct: 254 -----------SDCTLKILDFGLARTAIEAFMMTPYVVTRYYRAPEVILGMGY-KENVDV 301
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHS-INGKEHFGGSWLDSKPLYQA 326
W+ GC+ EL LFPG D DQ RI++ LG+PD S + + ++++++P YQA
Sbjct: 302 WSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTVRNYVENRPRYQA 361
Query: 327 LNYEFPYVEG----KTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
+E + + L Q DL ++ L +P R + ++ PY
Sbjct: 362 TPFEVLFSDNMFPMTADSSRLTGAQARDL---LSRMLVIDPERRISVDDALRHPY 413
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 102 bits (253), Expect = 3e-21
Identities = 81/274 (29%), Positives = 123/274 (44%), Gaps = 39/274 (14%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLR 170
+REIK + Q+ H+NLV + E+ ++L V E ++ I ++ + ++
Sbjct: 49 MREIKLLKQL-RHENLVNLLEVCKKKKRWYL--VFEFVDHTILDDLELFPNGL-DYQVVQ 104
Query: 171 SILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGL 230
LFQI+ G PENIL+S S VVKL D+G
Sbjct: 105 KYLFQIINGIGFCHSHNIIHRDIKPENILVSQSG-----------------VVKLCDFGF 147
Query: 231 ARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDE 289
AR + YT YV+TRWYR+PE+L+ Y K +D+WA GC+V E+ PLFPG +
Sbjct: 148 ARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSD 207
Query: 290 TDQIWRILDLLGS--PDHS--INGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPN 345
DQ++ I+ LG+ P H N F G L + L +P +
Sbjct: 208 IDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLS---------- 257
Query: 346 PQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
E + D+ CL +P +R E+ +F+
Sbjct: 258 ---EVVIDLAKKCLHIDPDKRPFCAELLHHDFFQ 288
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 102 bits (253), Expect = 3e-21
Identities = 83/279 (29%), Positives = 132/279 (46%), Gaps = 40/279 (14%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHR-KRRVFSLP 167
T VREI + ++ H N+V + + + ++ L ++ E + ++ + M K L
Sbjct: 65 TAVREISLLKELQ-HPNVVGLEAVIMQEN--RLFLIFEFLSFDLKRYMDQLGKDEYLPLE 121
Query: 168 TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
TL+S FQIL P+N+L+ +N +KLAD
Sbjct: 122 TLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVD-----------------NNGAIKLAD 164
Query: 228 YGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPG 286
+GLAR + YT V T WYR+PEIL+ YS +D+W+ GC+ E+AT PLF G
Sbjct: 165 FGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATKKPLFQG 224
Query: 287 SDETDQIWRILDLLGSP-DHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPN 345
E D+++RI +LG+P + NG ++S P Y+A FP +RD +
Sbjct: 225 DSEIDELFRIFRVLGTPTELEWNG--------VESLPDYKA---TFPKWRENFLRDKFYD 273
Query: 346 PQ-----LED-LYDVVTSCLKWNPSERATANEICALPYF 378
+ L+D + ++ L ++PS R A + PYF
Sbjct: 274 KKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF 312
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 102 bits (253), Expect = 3e-21
Identities = 76/274 (27%), Positives = 122/274 (43%), Gaps = 36/274 (13%)
Query: 107 DYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
++T +REIK + ++ H ++V + + F D LH+V E M+ ++ ++ R R +F
Sbjct: 54 NFTALREIKLLKELN-HPHIVELIDAFPHDG--SLHLVFEYMQTDLEAVI--RDRNIFLS 108
Query: 167 P-TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
P ++S + L G P N+LI +N ++KL
Sbjct: 109 PGDIKSYMLMTLKGLAYCHKKWVLHRDMKPNNLLIG-----------------ENGLLKL 151
Query: 226 ADYGLARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
AD+GLAR + + +T V WYR+PE+L Y +D+WA GC+ EL P
Sbjct: 152 ADFGLARLFGSPNRRFTHQVFATWYRAPELLFGSRQYGAGVDVWAAGCIFAELLLRRPFL 211
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PGS E DQ+ +I G+P S W D +Y EF Y +R + P
Sbjct: 212 PGSTEIDQLGKIFQAFGTPVPS---------QWSDM--IYLPDYMEFSYTPAPPLRTIFP 260
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
+D D++ ++P +R T + YF
Sbjct: 261 MAS-DDALDLLAKMFIYDPRQRITIQQALDHRYF 293
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 101 bits (252), Expect = 4e-21
Identities = 83/298 (27%), Positives = 132/298 (43%), Gaps = 33/298 (11%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDS----LYHLHIVMECM 148
VAIK M R +L H N++ + F D+ +++VME M
Sbjct: 64 VAIKKMQQPFVMTMSAKRAYREFILLTTIKHPNIIRLLNAFTPDTSLSTFREVYLVMELM 123
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
N+++++ HR R TL ++Q L P NI+++
Sbjct: 124 THNLHEVI-HRLR--LDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVN------- 173
Query: 209 KKWLEDDNYSDNYVVKLADYGLAR--HVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
D V+K+ D+GLAR +V+ + YV TR+YR+PE++L Y S+ +D
Sbjct: 174 ----------DRCVLKVLDFGLARKKNVDTSMRMSDYVVTRYYRAPEVILGLPY-SEKVD 222
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP-DHSINGKEHFGGSWLDSKPLYQ 325
IW+ GC+ E+ + LFPG D DQ +I +LG+P DH I+ ++ S P +Q
Sbjct: 223 IWSVGCIFAEMINHTVLFPGKDRIDQWTKIYSVLGTPDDHFISQLGQSAAMYVRSLPRHQ 282
Query: 326 ALNYEFPYVEGKTIRDVLPNPQL----EDLYDVVTSCLKWNPSERATANEICALPYFK 379
A + V NP++ D++ + LK NP ER + + PY K
Sbjct: 283 ARAFS-EIVPDTNFLPETENPRVHLTPHVARDLLFNMLKINPEERYSVEDALNHPYVK 339
>Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 1030
Score = 101 bits (251), Expect = 5e-21
Identities = 88/315 (27%), Positives = 153/315 (47%), Gaps = 39/315 (12%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +RE+K +L+ +N+V + E F L++V E +E+N+ +L++ V
Sbjct: 56 TTLRELK-MLRTLKQENIVELKEAFRRRG--KLYLVFEYVEKNMLELLEEMPNGV-PPEK 111
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
++S ++Q++ PEN+LIS N V+KL D+
Sbjct: 112 VKSYIYQLIKAIHWCHKNDIVHRDIKPENLLIS-----------------HNDVLKLCDF 154
Query: 229 GLARHVN--NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPG 286
G AR+++ N + YT YV+TRWYRSPE+LL Y K +D+W+ GC++ EL+ PLFPG
Sbjct: 155 GFARNLSEGNNANYTEYVATRWYRSPELLLGAPY-GKSVDMWSVGCILGELSDGQPLFPG 213
Query: 287 SDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNY---EFPYVEGKTIRDVL 343
E DQ++ I +LG P S K + S P + L + P + +L
Sbjct: 214 ESEIDQLFTIQKVLG-PLPSEQMKLFY------SNPRFHGLRFPAVNHPQSLERRYLGIL 266
Query: 344 PNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNGTASKNKDNT 403
+ L D++ + LK +P++R + P F+ + + S +++ + +++
Sbjct: 267 NSV----LLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAK-RKPYHVESS 321
Query: 404 ALANKLAANPSISNQ 418
L+N+ A S + Q
Sbjct: 322 TLSNRNQAGKSTALQ 336
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 101 bits (251), Expect = 5e-21
Identities = 65/284 (22%), Positives = 131/284 (45%), Gaps = 36/284 (12%)
Query: 112 REIKFILQIPAHKNLVTIYEMFID-----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
RE++ + ++ H N+V + F D LY L++++E + + +Y++ +H ++ +
Sbjct: 76 RELQIMRKLN-HPNIVKLKYFFYSSGEKKDELY-LNLILEYVPETVYRVARHYSKQRQQI 133
Query: 167 PTL--RSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
P + + ++Q+L P+N+LI P ++ V+K
Sbjct: 134 PMIYVKLYMYQLLRSLAYIHSIGICHRDIKPQNLLIDP----------------ESGVLK 177
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
L D+G A+++ P +Y+ +R+YR+PE++ Y+ +D+W+ G V+ EL P+F
Sbjct: 178 LCDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATNYTNSIDVWSAGTVMAELLLGQPIF 237
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG DQ+ I+ +LG+P P Y+ ++FP ++ V
Sbjct: 238 PGDSGVDQLVEIIKVLGTPTRE---------QIQSMNPNYK--EFKFPQIKAHPWNKVFR 286
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASL 388
+ D+++ +++ P+ R T C +F E +A L
Sbjct: 287 VHTPAEAIDLISKIIEYTPTSRPTPQAACQHAFFDELRNPDARL 330
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 101 bits (251), Expect = 5e-21
Identities = 82/312 (26%), Positives = 135/312 (42%), Gaps = 39/312 (12%)
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVME 146
+ K VA+K + + D R RE+ F+ H N+V + ++F + ++V E
Sbjct: 46 RTKNTVALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKASNNLDFYLVFE 105
Query: 147 CMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRY 206
ME +++ ++K + V R +++Q++ P NILI R
Sbjct: 106 FMESDLHNVIK--RGNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILIDSKCR- 162
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPY---------TTYVSTRWYRSPEILLR 257
+K+AD+GLAR +++R Y T YV+TRWYR+PEIL+
Sbjct: 163 ----------------LKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEILVA 206
Query: 258 KGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDH-SINGKEHFGGS 316
Y+K +D+W GC++ E+ PLF G+ +QI +I+ L + I GS
Sbjct: 207 SRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKIVTSLPNVTKLDIASIGPSFGS 266
Query: 317 WLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALP 376
L S+ + + Y D + +D +V + L NP R TA E P
Sbjct: 267 VLLSRNIQRDRRYSL---------DEMMKNCCDDGISLVKALLVLNPHNRLTAKEAIRHP 317
Query: 377 YFKEYVMREASL 388
Y + A +
Sbjct: 318 YVSRFQYASAEM 329
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 100 bits (250), Expect = 6e-21
Identities = 96/384 (25%), Positives = 166/384 (43%), Gaps = 48/384 (12%)
Query: 111 VREIKFILQIPAHKNLVTIYEMF------IDDSLYHL---HIVMECMEQNIYQLMKHRKR 161
+REIK I ++ H N+V +YE+ + L+ +IV E ME ++ +L++ +
Sbjct: 63 LREIKIIRRLD-HDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLE---Q 118
Query: 162 RVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNY 221
+ + ++Q+L G P NI IS +++
Sbjct: 119 GTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFIS----------------TEDL 162
Query: 222 VVKLADYGLARHVNNRSPYTTYVS----TRWYRSPEILLRKGYYSKPLDIWAYGCVVVEL 277
V+K+ D+GLAR V+ + Y+S T+WYRSP +LL Y+K +D+WA GC++ E+
Sbjct: 163 VLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEM 222
Query: 278 ATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGK 337
T LF G+ E +Q+ IL+ + +E L P + + +E +
Sbjct: 223 LTGRMLFAGAHELEQMQLILETIPVI------REEDKDELLRVMPSFVSSTWEVK----R 272
Query: 338 TIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNGTAS 397
+R +LP E + D + L +NP +R TA PY Y E +
Sbjct: 273 PLRKLLPEVNSEAI-DFLEKILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIE 331
Query: 398 KNKDNTALANKLAANPSISNQWSRILSGLPHNPELGIVPSFNSPQKLPKVQKNNQ-MNCV 456
D+ L +AAN S + W S P + + + Q +VQ++ + +
Sbjct: 332 DEIDDIVL---MAANQSQLSNWDTCSSRYPVSLSSDLEWRPDRCQDASEVQRDPRGFGAL 388
Query: 457 TDKSQQQPRRGGVASWFKFSTQKN 480
+ Q PR+ +S +F Q +
Sbjct: 389 AEDVQVDPRKDSHSSSERFLEQSH 412
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 100 bits (250), Expect = 6e-21
Identities = 74/284 (26%), Positives = 128/284 (45%), Gaps = 32/284 (11%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +RE+ + + H N+VT++++ D L +V E ++ ++ Q + H + S+
Sbjct: 184 TAIREVSLLKNLK-HANIVTLHDLIHTDR--SLTLVFEYLDSDLKQYLDHCGN-LMSMHN 239
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
++ +FQ+L G P+N+LI+ + +KLAD+
Sbjct: 240 VKIFMFQLLRGLAYCHHRKILHRDLKPQNLLIN-----------------ERGELKLADF 282
Query: 229 GLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLAR + Y+ V T WYR P++LL YS P+D+W GC+ E+AT PLFPGS
Sbjct: 283 GLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGS 342
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQ 347
+++ I LLG+P +W + Y FP + + + P
Sbjct: 343 TVKEELHLIFRLLGTPTEE---------TWPGVTAFSEFRTYSFPCYLPQPLINHAPRLD 393
Query: 348 LEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKT 391
+ ++ +++S L + R +A + YF+ R L T
Sbjct: 394 TDGIH-LLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQLEDT 436
>ECU11g0180 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 405
Score = 100 bits (250), Expect = 6e-21
Identities = 85/276 (30%), Positives = 122/276 (43%), Gaps = 54/276 (19%)
Query: 27 KNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWY 86
KN +Y +I LG G+FG V + S +++ I+ V+ + Y
Sbjct: 34 KNKSQKYMIIDMLGTGTFGQVVRC-----VGSDGEEVA------------IKVVKNQPKY 76
Query: 87 YKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVME 146
Y + MN + LH +L + VTI ++F+ HL IV E
Sbjct: 77 YNYE--------MNEVRILHK---------LLYNNLNDRFVTIKDVFMYKQ--HLCIVEE 117
Query: 147 CMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRY 206
+ +N+Y +K + + PTLR+IL QIL G PENILI+
Sbjct: 118 LLGRNLYTFLKMTRFKGLDHPTLRTILHQILEGMVQLSLLGIIHCDLKPENILIAD---- 173
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
D + +K+ D+G A V + YV +R+YR+PE++L Y S D
Sbjct: 174 -----------YDTFKIKIIDFGSA--VTSPQGSHFYVQSRYYRAPEVILGIPYGSS-CD 219
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS 302
IW+ GC+ EL PLFPG D DQI RI L GS
Sbjct: 220 IWSLGCIGYELYVGHPLFPGKDNMDQIGRIHGLFGS 255
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 100 bits (250), Expect = 6e-21
Identities = 72/286 (25%), Positives = 130/286 (45%), Gaps = 46/286 (16%)
Query: 105 LHDYTRVREIKFILQIPAHKNLVTIYEMFID-------DSLYHLHIVMECMEQNIYQLMK 157
+H RE++ +L+ H+N++ + ++F + +Y + ++M NI ++ +
Sbjct: 74 IHARRTYRELR-LLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLMGADLSNILKIQR 132
Query: 158 HRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNY 217
+ + +++QIL G P NI ++
Sbjct: 133 LNDDHI------QFLVYQILRGLKYIHSADIIHRDLKPSNIAVN---------------- 170
Query: 218 SDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVEL 277
++ +K+ D+GLAR + S T YV+TRWYR+PEI+L +Y++ +D+W+ GC++ EL
Sbjct: 171 -EDCELKILDFGLARQTD--SEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAEL 227
Query: 278 ATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNY--EFPYVE 335
T LFPGSD DQ+ RI+ + G+PD +L +A NY P +
Sbjct: 228 ITGKTLFPGSDHIDQLTRIMSVTGTPDE----------EFLKKISSEEARNYIRNLPKMT 277
Query: 336 GKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
+ + + + + D++ L +P R TA E Y Y
Sbjct: 278 RRDFKRLFAQATPQAI-DLLEKMLHLDPDRRPTAKEAMEHEYLAAY 322
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 100 bits (250), Expect = 6e-21
Identities = 76/282 (26%), Positives = 132/282 (45%), Gaps = 47/282 (16%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLM------KHRKRR 162
T +REI + ++ H+N+V + ++ ++++ ++++ E + ++ + M KH +
Sbjct: 47 TAIREISLLKELK-HENIVCLEDVLMEEN--RIYLIFEFLSMDLKKYMDSLPVDKHMESE 103
Query: 163 VFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYV 222
+ +RS L+QI + P+N+LI S +
Sbjct: 104 L-----VRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSG-----------------L 141
Query: 223 VKLADYGLARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFS 281
+K+AD+GL R YT + T WYR+PE+LL YS P+DIW+ GC+ E+AT
Sbjct: 142 IKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRK 201
Query: 282 PLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSW--LDSKPLYQALNYEFPYVEGKTI 339
PLF G E DQ++R+ +L +P I W + S P Y+ FP +
Sbjct: 202 PLFQGDSEIDQLFRMFRILKTPTEDI---------WPGVTSLPDYK---NTFPCWSTNQL 249
Query: 340 RDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
+ L N + D++ L ++P R +A +I PYF +
Sbjct: 250 TNQLKNLDANGI-DLIQKMLIYDPVHRISAKDILEHPYFNGF 290
>7291976 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1320
Score = 100 bits (250), Expect = 6e-21
Identities = 87/319 (27%), Positives = 136/319 (42%), Gaps = 60/319 (18%)
Query: 26 LKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENW 85
L ++ A Y V++ LG+G+FG V A +I +P
Sbjct: 185 LYSLSAEYEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPS---------------- 228
Query: 86 YYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPA--HKNLVTIYEMFIDDSLYHLHI 143
Y ++G + + ++++RL E F+ HKN H +
Sbjct: 229 -YARQGQIEV-SILSRL----SQENADEFNFVRAFECFQHKN--------------HTCL 268
Query: 144 VMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPS 203
V E +EQN+Y +K K L +R IL Q+L PENI++
Sbjct: 269 VFEMLEQNLYDFLKQNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLV-- 326
Query: 204 HRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSK 263
D Y VK+ D+G A HV+ ++ TY+ +R+YR+PEI+L + +
Sbjct: 327 -----------DPVRQPYRVKVIDFGSASHVS-KTVCNTYLQSRYYRAPEIILGLPF-CE 373
Query: 264 PLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP-DHSINGKEHFGGSWLDSKP 322
+D+W+ GCVV EL PL+PGS E DQI I G P +H +N SK
Sbjct: 374 AIDMWSLGCVVAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASK------TSKF 427
Query: 323 LYQALNYEFPYVEGKTIRD 341
Y+ ++ +P+ KT +
Sbjct: 428 FYRDVDSTYPFWRLKTTEE 446
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 100 bits (249), Expect = 8e-21
Identities = 75/285 (26%), Positives = 134/285 (46%), Gaps = 45/285 (15%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRK----RRVF 164
T +REI + ++ H+N+V +Y++ ++ L +V E M+ ++ + M R R
Sbjct: 49 TAIREISLMKELK-HENIVRLYDVIHTEN--KLTLVFEFMDNDLKKYMDSRTVGNTPRGL 105
Query: 165 SLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
L ++ +Q+L G P+N+LI+ + +K
Sbjct: 106 ELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQ-----------------LK 148
Query: 225 LADYGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPL 283
L D+GLAR + +++ V T WYR+P++L+ YS +DIW+ GC++ E+ T PL
Sbjct: 149 LGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPL 208
Query: 284 FPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDV- 342
FPG+++ +Q+ I D++G+P+ S+ W P L P ++ + RD+
Sbjct: 209 FPGTNDEEQLKLIFDIMGTPNESL---------W----PSVTKLPKYNPNIQQRPPRDLR 255
Query: 343 ------LPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
P +L D + L+ NP R +A + P+F EY
Sbjct: 256 QVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEY 300
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 100 bits (249), Expect = 8e-21
Identities = 72/272 (26%), Positives = 124/272 (45%), Gaps = 32/272 (11%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +RE+ + + H N+VT++++ D L +V E +++++ Q M + S+
Sbjct: 234 TAIREVSLLKDLK-HANIVTLHDIVHTDK--SLTLVFEYLDKDLKQYMDDCGN-IMSMHN 289
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
++ L+QIL G P+N+LI+ +KLAD+
Sbjct: 290 VKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGE-----------------LKLADF 332
Query: 229 GLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLAR + Y+ V T WYR P++LL Y +D+W GC+ E+A+ PLFPGS
Sbjct: 333 GLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYLTQIDMWGVGCIFFEMASGRPLFPGS 392
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQ 347
D++ I LLG+P +W + NY FP + + + + P
Sbjct: 393 TVEDELHLIFRLLGTPSQE---------TWPGISSNEEFKNYNFPKYKPEPLINHAPRLD 443
Query: 348 LEDLYDVVTSCLKWNPSERATANEICALPYFK 379
E + +++ L++ +R +A E YF+
Sbjct: 444 SEGI-ELIRKFLQYESKKRVSAEEAMKHVYFR 474
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 100 bits (249), Expect = 8e-21
Identities = 76/275 (27%), Positives = 126/275 (45%), Gaps = 37/275 (13%)
Query: 106 HDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFS 165
H+ + +REIK + +I + K +V + + F+ D +HIV+E +E N+ ++++ + +
Sbjct: 57 HEISAIREIKSLKRIDS-KYVVRLIDTFVYDKC--VHIVLEYVETNLENVIRNSDKIIMP 113
Query: 166 LPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
+++ + +L G P NILI+ +VKL
Sbjct: 114 -GDIKAWILMVLRGVYECHRLFIIHRDIKPNNILITSEG-----------------MVKL 155
Query: 226 ADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFP 285
AD+GL R + NR T TRWYR+PE+L+ Y P+D+W+ GCV EL PLF
Sbjct: 156 ADFGLTRGIGNRM--TPQAVTRWYRAPELLMGSRDYGSPVDMWSVGCVFAELFLRVPLFA 213
Query: 286 GSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNY-EFPYVEGKTIRDVLP 344
G + Q+ I LG+P W L + L++ ++P K + L
Sbjct: 214 GDTDIQQLDMIFRALGTPVER---------EWPGVSTLPEFLDFQQYP----KASLNGLF 260
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
+ D D++ L NP R + ++ PYFK
Sbjct: 261 SAASSDALDLLEKLLTLNPCNRISCDDAIKHPYFK 295
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 100 bits (248), Expect = 1e-20
Identities = 71/288 (24%), Positives = 135/288 (46%), Gaps = 38/288 (13%)
Query: 112 REIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLP 167
RE++ I+++ H N+V + F D LY L++V+E + + +Y+ KH + +P
Sbjct: 178 RELQ-IMRLQDHPNVVRLRHSFFSTTDKDELY-LNLVLEYVPETVYRASKHYTKMNQHMP 235
Query: 168 TL--RSILFQILAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
+ + +QI P+N+L++P + +K
Sbjct: 236 IIFVQLYTYQICRALNYLHRVVGVCHRDIKPQNLLVNPQ----------------THQLK 279
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
+ D+G A+ + P +Y+ +R+YR+PE++ Y+ +D+W+ GCV+ EL PLF
Sbjct: 280 ICDFGSAKMLVPGEPNISYICSRYYRAPELIFGATEYTNAIDMWSGGCVMAELLLGQPLF 339
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG DQ+ I+ +LG+P P Y ++FP ++ +
Sbjct: 340 PGESGIDQLVEIIKILGTPTRE---------EIRCMNPNY--TEFKFPQIKAHPWHKIFH 388
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTN 392
+ D+V+ L+++P+ R TA E CA P+F + +R+ +++ N
Sbjct: 389 KRMPPEAVDLVSRLLQYSPNLRCTALEACAHPFFDD--LRDPNVSLPN 434
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/280 (29%), Positives = 128/280 (45%), Gaps = 47/280 (16%)
Query: 107 DYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
D + +REIKF+ + H N++ + ++F S +L+I++E ++ ++ L+K K VF
Sbjct: 52 DISALREIKFLRE-SRHDNVIELVDVFSTKS--NLNIILEFLDSDLEMLIKD-KFIVFQP 107
Query: 167 PTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLA 226
++S + +L G P N+LIS SD V+KLA
Sbjct: 108 AHIKSWMVMLLRGLHHIHSRFILHRDLKPNNLLIS----------------SDG-VLKLA 150
Query: 227 DYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPG 286
D+GL+R S + V TRWYR PE+ + Y +D+W+ GC+ EL +P PG
Sbjct: 151 DFGLSRDFGTPSHMSHQVITRWYRPPELFMGCRSYGTGVDMWSVGCIFAELMLRTPYLPG 210
Query: 287 SDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNP 346
+ DQ+ I LG+P+ + K + Q N YVE K I PN
Sbjct: 211 ESDLDQLNVIFRALGTPEPEV------------IKSMQQLPN----YVEMKHIPP--PNG 252
Query: 347 QLEDLY--------DVVTSCLKWNPSERATANEICALPYF 378
+E L+ D++ L +NP R TA + YF
Sbjct: 253 GMEALFSAAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYF 292
>At3g18040 [T] KOG0660 Mitogen-activated protein kinase
Length = 613
Score = 99.8 bits (247), Expect = 1e-20
Identities = 83/303 (27%), Positives = 142/303 (46%), Gaps = 54/303 (17%)
Query: 93 VAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFIDDS---LYHLHIVMECM 148
VAIK + + + D TR+ REIK +L++ H ++V I + + S +++V E M
Sbjct: 152 VAIKKINDVFEHVSDATRILREIK-LLRLLRHPDIVEIKHVMLPPSRREFRDIYVVFELM 210
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
E +++Q++K + + L+Q+L G P+NIL + +
Sbjct: 211 ESDLHQVIKANDD--LTPEHYQFFLYQLLRGLKFIHTANVFHRDLKPKNILANSDCK--- 265
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSP----YTTYVSTRWYRSPEILLRKGYYSK- 263
+K+ D+GLAR N +P +T YV+TRWYR+PE+ ++SK
Sbjct: 266 --------------LKICDFGLARVSFNDAPSAIFWTDYVATRWYRAPELC--GSFFSKY 309
Query: 264 --PLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK------EHFGG 315
+DIW+ GC+ E+ T PLFPG + Q+ + DLLG+P + + G
Sbjct: 310 TPAIDIWSIGCIFAEMLTGKPLFPGKNVVHQLDIMTDLLGTPPPEAIARIRNEKARRYLG 369
Query: 316 SWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICAL 375
+ P+ ++FP+V+ +R ++ L ++P +R +A E A
Sbjct: 370 NMRRKPPV--PFTHKFPHVDPLALR-------------LLHRLLAFDPKDRPSAEEALAD 414
Query: 376 PYF 378
PYF
Sbjct: 415 PYF 417
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 99.8 bits (247), Expect = 1e-20
Identities = 77/308 (25%), Positives = 151/308 (49%), Gaps = 42/308 (13%)
Query: 93 VAIKTMMNRLPT-LHDYTRVREIKFILQIPAHKNLVTIYEMFID-------DSLYHLHIV 144
VAIK + + +H RE++ + + H+N++ + ++F ++ +++V
Sbjct: 51 VAIKKLARPFQSAVHAKRTYRELRLLKHMD-HENVIGLLDIFHPHPANGSLENFQQVYLV 109
Query: 145 MECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH 204
M+ ++ +++ + S ++ +++QIL G P NI ++
Sbjct: 110 THLMDADLNNIIRMQH---LSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVN--- 163
Query: 205 RYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKP 264
++ +++ D+GLAR N T YV+TRWYR+PEI+L +Y +
Sbjct: 164 --------------EDCELRILDFGLARPTENEM--TGYVATRWYRAPEIMLNWMHYDQT 207
Query: 265 LDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLY 324
+DIW+ GC++ EL T LFPG+D Q+ I+++LG+P K S ++
Sbjct: 208 VDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKI----SSESARSYI 263
Query: 325 QALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMR 384
Q+L P ++G++ ++V N + D++ L+ + +R TA E + PY ++Y
Sbjct: 264 QSL----PPMKGRSFKNVFKNANPLAI-DLLEKMLELDAEKRITAEEALSHPYLEKYA-- 316
Query: 385 EASLAKTN 392
E S+ +T+
Sbjct: 317 EPSVEQTS 324
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 99.8 bits (247), Expect = 1e-20
Identities = 88/289 (30%), Positives = 130/289 (44%), Gaps = 59/289 (20%)
Query: 108 YTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMK-------HRK 160
+T +RE + ++ H N+VT+++ I + L V E + ++ Q M+ HR
Sbjct: 233 FTAIREASLLKELK-HSNIVTLHD--IVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRN 289
Query: 161 RRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDN 220
R+F LFQ+L G P+N+LIS D
Sbjct: 290 VRLF--------LFQLLRGLSYCHKRRVLHRDVKPQNLLIS-----------------DC 324
Query: 221 YVVKLADYGLARHVNNRS-PYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELAT 279
+KLAD+GLAR + S Y+ V T WYR P++LL YS LD+W GC+ VE+ T
Sbjct: 325 GELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVT 384
Query: 280 FSPLFPGSDET-DQIWRILDLLGSP-DHSINGKEHFGGSWLDSKPLY--QALNYEFP--- 332
P FPG +T DQ+ +I LLG+P + + G HF G Y + L + FP
Sbjct: 385 GMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLY 444
Query: 333 -YVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+EG+TI L+ NP +R A++ PYF +
Sbjct: 445 DIIEGETI---------------ANGFLQLNPEQRLGADDALQHPYFAQ 478
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 99.4 bits (246), Expect = 2e-20
Identities = 73/294 (24%), Positives = 133/294 (44%), Gaps = 34/294 (11%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VA+K + R +L+ HKN++++ +F + +++VME M
Sbjct: 52 VAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELM 111
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q++ + +L+Q+L G P NI++
Sbjct: 112 DANLCQVIHME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 160
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +DIW
Sbjct: 161 ----------SDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGY-KENVDIW 209
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ E+ LFPG D DQ ++++ LG+P K + ++++++P Y +
Sbjct: 210 SVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGI 269
Query: 328 NYE--FP--YVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
+E FP ++ RD + Q DL ++ L +P +R + +E PY
Sbjct: 270 KFEELFPDWIFPSESERDKIKTSQARDL---LSKMLVIDPDKRISVDEALRHPY 320
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 99.4 bits (246), Expect = 2e-20
Identities = 73/294 (24%), Positives = 133/294 (44%), Gaps = 34/294 (11%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VA+K + R +L+ HKN++++ +F + +++VME M
Sbjct: 52 VAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELM 111
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q++ + +L+Q+L G P NI++
Sbjct: 112 DANLCQVIHME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 160
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +DIW
Sbjct: 161 ----------SDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGY-KENVDIW 209
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ E+ LFPG D DQ ++++ LG+P K + ++++++P Y +
Sbjct: 210 SVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGI 269
Query: 328 NYE--FP--YVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
+E FP ++ RD + Q DL ++ L +P +R + +E PY
Sbjct: 270 KFEELFPDWIFPSESERDKIKTSQARDL---LSKMLVIDPDKRISVDEALRHPY 320
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 99.4 bits (246), Expect = 2e-20
Identities = 75/296 (25%), Positives = 141/296 (47%), Gaps = 41/296 (13%)
Query: 93 VAIKTMMNRLPTL-HDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMEC 147
VA+K + ++ H RE++ +L+ H+N++ + ++F + +++V
Sbjct: 50 VAVKKLSRPFQSIIHAKRTYRELR-LLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHL 108
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
M ++ ++K +K + ++ +++QIL G P N+ ++
Sbjct: 109 MGADLNNIVKCQK---LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVN------ 159
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
++ +K+ D+GLARH ++ T YV+TRWYR+PEI+L +Y++ +DI
Sbjct: 160 -----------EDCELKILDFGLARHTDDEM--TGYVATRWYRAPEIMLNWMHYNQTVDI 206
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK--EHFGGSWLDSKPLYQ 325
W+ GC++ EL T LFPG+D DQ+ IL L+G+P + K +++ S
Sbjct: 207 WSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMP 266
Query: 326 ALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
+N+ ++ NP DL + L + +R TA + A YF +Y
Sbjct: 267 KMNFANVFIGA--------NPLAVDLLE---KMLVLDSDKRITAAQALAHAYFAQY 311
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 99.0 bits (245), Expect = 2e-20
Identities = 74/274 (27%), Positives = 127/274 (46%), Gaps = 32/274 (11%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKH-RKRRVFSLP 167
T +REI + ++ N+V +Y++ D+ + L++V E ++ ++ + M+ K +
Sbjct: 54 TAIREISLLKELK-DDNIVRLYDIVHSDA-HKLYLVFEFLDLDLKRYMEGIPKDQPLGAD 111
Query: 168 TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
++ + Q+ G P+N+LI+ +D N +KL D
Sbjct: 112 IVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLIN-----------KDGN------LKLGD 154
Query: 228 YGLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPG 286
+GLAR YT + T WYR+PE+LL YS +D W+ GC+ E+ P+F G
Sbjct: 155 FGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSG 214
Query: 287 SDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNP 346
E DQI++I +LG+P+ +I W D L FP K + V+P+
Sbjct: 215 DSEIDQIFKIFRVLGTPNEAI---------WPDIVYL-PDFKPSFPQWRRKDLSQVVPSL 264
Query: 347 QLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ D++ L ++P R +A PYF+E
Sbjct: 265 DPRGI-DLLDKLLAYDPINRISARRAAIHPYFQE 297
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 99.0 bits (245), Expect = 2e-20
Identities = 73/296 (24%), Positives = 142/296 (47%), Gaps = 41/296 (13%)
Query: 93 VAIKTMMNRLPTL-HDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMEC 147
VA+K + ++ H RE++ +L+ H+N++ + ++F + +++V
Sbjct: 50 VAVKKLSRPFQSIIHAKRTYRELR-LLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHL 108
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
M ++ ++K +K + ++ +++QIL G P N+ ++
Sbjct: 109 MGADLNNIVKCQK---LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVN------ 159
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
++ +K+ D+GLARH ++ T YV+TRWYR+PEI+L +Y++ +DI
Sbjct: 160 -----------EDCELKILDFGLARHTDDEM--TGYVATRWYRAPEIMLNWMHYNQTVDI 206
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK--EHFGGSWLDSKPLYQ 325
W+ GC++ EL T LFPG+D +Q+ +I+ L G+P + + H +++ S
Sbjct: 207 WSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHEARNYIQSLTQMP 266
Query: 326 ALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
+N+ ++ NP DL + L + +R TA + A YF +Y
Sbjct: 267 KMNFANVFIGA--------NPLAVDLLE---KMLVLDSDKRITAAQALAHAYFAQY 311
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 99.0 bits (245), Expect = 2e-20
Identities = 75/272 (27%), Positives = 125/272 (45%), Gaps = 36/272 (13%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REIK +LQ +H N++ + + F S ++ +V + ME ++ ++K V +
Sbjct: 58 TALREIK-LLQELSHPNIIGLLDAFGHKS--NISLVFDFMETDLEVIIKDNSL-VLTPSH 113
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
+++ + L G P N+L+ +N V+KLAD+
Sbjct: 114 IKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLD-----------------ENGVLKLADF 156
Query: 229 GLARHVNNRS-PYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLA+ + + YT V TRWYR+PE+L Y +D+WA GC++ EL P PG
Sbjct: 157 GLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGD 216
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYE-FPYVEGKTIRDVLPNP 346
+ DQ+ RI + LG+P W D L + ++ FP G + + +
Sbjct: 217 SDLDQLTRIFETLGTPTEE---------QWPDMCSLPDYVTFKSFP---GIPLHHIF-SA 263
Query: 347 QLEDLYDVVTSCLKWNPSERATANEICALPYF 378
+DL D++ +NP R TA + + YF
Sbjct: 264 AGDDLLDLIQGLFLFNPCARITATQALKMKYF 295
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 99.0 bits (245), Expect = 2e-20
Identities = 72/274 (26%), Positives = 128/274 (46%), Gaps = 35/274 (12%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHR--KRRVFSL 166
T +REI +L+ H +V + ++ +++ +++V E +E ++ + + + R+
Sbjct: 48 TTIREI-LLLKNLKHSTIVELSDVIYNNN--KMYLVFEYVELDLRRYLDRMSDEGRLVEE 104
Query: 167 PTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLA 226
+R + Q+L P+NIL+ P +KLA
Sbjct: 105 GFVRKMSQQLLTAMEYCHSRNIFHRDLKPQNILVDPKEN-----------------IKLA 147
Query: 227 DYGLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFP 285
D+GL R YTT V T WYR PE+LL YY +D+W+ C++ E+ P FP
Sbjct: 148 DFGLGRAAGIPLRTYTTEVVTLWYRPPELLLGCKYYDASVDVWSAACIMAEVVLMRPFFP 207
Query: 286 GSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPN 345
G E DQ++RI +LG+P++S S +++ P Y+ EFP + ++ +
Sbjct: 208 GDSEIDQLFRIFKVLGTPNNS-------RWSNVENFPNYKV---EFPVWDPVDLKTIFRG 257
Query: 346 PQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
D D+++ L+++P R TA + YF+
Sbjct: 258 D--PDFVDLISKMLEYDPKMRMTAKNGLSHKYFE 289
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 99.0 bits (245), Expect = 2e-20
Identities = 77/301 (25%), Positives = 140/301 (45%), Gaps = 48/301 (15%)
Query: 93 VAIKTMMNRLPT-LHDYTRVREIKFILQIPAHKNLVTIYEMFID-------DSLYHLHIV 144
VAIK + + +H RE++ + + H+N++ + ++F D +++V
Sbjct: 50 VAIKKLARPFQSAVHAKRTYRELRLLKHMD-HENVIGLLDVFHPGQPADSLDQFQQVYMV 108
Query: 145 MECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH 204
M+ ++ +++ +K S ++ +++QIL G P NI ++
Sbjct: 109 THLMDADLNNIIRTQK---LSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVN--- 162
Query: 205 RYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKP 264
++ +++ D+GLAR S T YV+TRWYR+PEI+L +Y++
Sbjct: 163 --------------EDCELRILDFGLARPAE--SEMTGYVATRWYRAPEIMLNWMHYNQT 206
Query: 265 LDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLY 324
DIW+ GC++ EL T LFPG+D Q+ I+++LG+P ++
Sbjct: 207 ADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTP----------ADEFMSRISSE 256
Query: 325 QALNY--EFPYVEGKTIRDVL--PNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
A NY P + + RD+ NP DL + L+ + +R TA + A PY ++
Sbjct: 257 SARNYIRSLPVMPRRNFRDIFRGANPLAIDLLE---KMLELDADKRITAEQALAHPYMEK 313
Query: 381 Y 381
Y
Sbjct: 314 Y 314
>Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 385
Score = 98.6 bits (244), Expect = 3e-20
Identities = 78/293 (26%), Positives = 125/293 (42%), Gaps = 42/293 (14%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFS---LP 167
+REI+ + Q+ H NLV + E+F +H+V E + + ++ + S +
Sbjct: 49 LREIRMLKQLK-HPNLVNLIEVFRRKR--KMHLVFEYCDHTLLNELERNPNGMDSDSIVG 105
Query: 168 TLRSIL--FQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
LRS+ ++ PENILI+ ++K+
Sbjct: 106 RLRSVADRSRLAPKNNQIMILQCIHRDIKPENILITKQG-----------------IIKI 148
Query: 226 ADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFP 285
D+G A+ + YT YV+TRWYR+PE+L+ Y +DIWA GCV EL T PL+P
Sbjct: 149 CDFGFAQILIPGDAYTDYVATRWYRAPELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWP 208
Query: 286 GSDETDQIWRILDLLGS--PDHSINGKEH--FGGSWLDSKPLYQALNYEFPYVEGKTIRD 341
G + DQ++ I+ LG P H K + F G + + L +F V +
Sbjct: 209 GKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGISIPEPEDMETLEEKFSDVHPVAL-- 266
Query: 342 VLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNG 394
+ + CLK NP +R T +++ YF + + N G
Sbjct: 267 -----------NFMKGCLKMNPDDRLTCSQLLESSYFDSFQEAQIKRKARNEG 308
>At5g35980 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 787
Score = 98.6 bits (244), Expect = 3e-20
Identities = 81/270 (30%), Positives = 130/270 (48%), Gaps = 46/270 (17%)
Query: 85 WYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQI-----PAHKN-LVTIYEMFIDDSL 138
W + VA+K + N+L + E+ + + P KN +V IY+ F+ S
Sbjct: 140 WVPETNSFVAVKVIKNQLAYYQQ--ALVEVSILTTLNKKYDPEDKNHIVRIYDYFLHQS- 196
Query: 139 YHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENI 198
HL I E ++ N+Y+L+K + R SL ++ QIL G PENI
Sbjct: 197 -HLCICFELLDMNLYELIKINQFRGLSLSIVKLFSKQILLGLALLKDAGIIHCDLKPENI 255
Query: 199 LISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRK 258
L+ S + +K+ D+G A + +++ Y+ Y+ +R+YRSPE+LL
Sbjct: 256 LLCASVKPTE--------------IKIIDFGSAC-MEDKTVYS-YIQSRYYRSPEVLL-- 297
Query: 259 GY-YSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS--PDHSI----NGKE 311
GY Y+ +D+W++GC+V EL PLFPG E D + R++++LG PD+ + N +
Sbjct: 298 GYQYTTAIDMWSFGCIVAELFLGLPLFPGGSEFDILRRMIEILGKQPPDYVLKEAKNTNK 357
Query: 312 HF-----------GGSWLDSKPLYQALNYE 330
F GG++ K Y AL E
Sbjct: 358 FFKCVGSVHNLGNGGTYGGLKSAYMALTGE 387
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 98.6 bits (244), Expect = 3e-20
Identities = 74/272 (27%), Positives = 122/272 (44%), Gaps = 36/272 (13%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REIK ILQ H+N++ + ++F L ++ +V + M+ ++ ++K K + +
Sbjct: 58 TALREIK-ILQELQHENIIGLVDVF--GQLSNVSLVFDFMDTDLEVIIKDNKI-ILTQAN 113
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
+++ L G P N+L++ SD ++K+ D+
Sbjct: 114 IKAYAIMTLKGLEYLHLNWILHRDLKPNNLLVN----------------SDG-ILKIGDF 156
Query: 229 GLARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLA+ + + YT +V TRWYRSPE+L Y +D+WA GC++ EL P PG
Sbjct: 157 GLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDMWAVGCILAELMLRVPFMPGD 216
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNY-EFPYVEGKTIRDVLPNP 346
+ DQ+ RI LG+P + W L+ L + FP I N
Sbjct: 217 SDLDQLTRIFSTLGTPTEA---------EWPHLSKLHDYLQFRNFPGTPLDNIFTAAGN- 266
Query: 347 QLEDLYDVVTSCLKWNPSERATANEICALPYF 378
DL ++ NP R + E ++PYF
Sbjct: 267 ---DLIHLMQRLFAMNPLRRVSCREALSMPYF 295
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 97.8 bits (242), Expect = 5e-20
Identities = 79/330 (23%), Positives = 150/330 (44%), Gaps = 63/330 (19%)
Query: 112 REIKFILQIPAHKNLVTIYEMFID-----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
RE++ + ++ H N+V + F D +Y L++V++ + + +Y++ +H R +L
Sbjct: 96 RELQIMRKLD-HCNIVRLRYFFYSSGEKKDEVY-LNLVLDYVPETVYRVARHYSRAKQTL 153
Query: 167 PTL--RSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
P + + ++Q+ P+N+L+ P D V+K
Sbjct: 154 PVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDP----------------DTAVLK 197
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
L D+G A+ + P +Y+ +R+YR+PE++ Y+ +D+W+ GCV+ EL P+F
Sbjct: 198 LCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIF 257
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEG-------- 336
PG DQ+ I+ +LG+P + P Y ++FP ++
Sbjct: 258 PGDSGVDQLVEIIKVLGTPTRE---------QIREMNPNY--TEFKFPQIKAHPWTKDSS 306
Query: 337 ------KTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAK 390
+R P E + + + L++ P+ R T E CA +F E +R+ ++ K
Sbjct: 307 GTGHFTSGVRVFRPRTPPEAI-ALCSRLLEYTPTARLTPLEACAHSFFDE--LRDPNV-K 362
Query: 391 TNNGTASKNKDNTALAN----KLAANPSIS 416
NG +D AL N +L++NP ++
Sbjct: 363 LPNG-----RDTPALFNFTTQELSSNPPLA 387
>At2g42880 [T] KOG0660 Mitogen-activated protein kinase
Length = 594
Score = 97.8 bits (242), Expect = 5e-20
Identities = 88/303 (29%), Positives = 137/303 (45%), Gaps = 52/303 (17%)
Query: 93 VAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFIDDS---LYHLHIVMECM 148
VAIK + + + D R+ REIK +L++ H ++V I + + S +++V E M
Sbjct: 39 VAIKKIHDIFEHISDAARILREIK-LLRLLRHPDIVEIKHIMLPPSRREFKDIYVVFELM 97
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
E +++Q++K + + L+Q+L P+NIL +
Sbjct: 98 ESDLHQVIKANDD--LTREHYQFFLYQLLRALKYIHTANVYHRDLKPKNILANA------ 149
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSP----YTTYVSTRWYRSPEILLRKGYYSK- 263
N +K+ D+GLAR N +P +T YV+TRWYR+PE+ +YSK
Sbjct: 150 -----------NCKLKICDFGLARVAFNDTPTTIFWTDYVATRWYRAPELC--GSFYSKY 196
Query: 264 --PLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI-----NGKEHFGGS 316
+DIW+ GC+ E+ PLFPG + Q+ + DLLG+P N K +
Sbjct: 197 TPAIDIWSIGCIFAEVLMGKPLFPGKNVVHQLDLMTDLLGTPSLDTISRVRNEKARRYLT 256
Query: 317 WLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALP 376
+ KP P+ + D L LE L L ++P +R TA E A P
Sbjct: 257 SMRKKP-------PIPFAQKFPNADPLSLKLLERL-------LAFDPKDRPTAEEALADP 302
Query: 377 YFK 379
YFK
Sbjct: 303 YFK 305
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 97.4 bits (241), Expect = 7e-20
Identities = 73/280 (26%), Positives = 129/280 (46%), Gaps = 37/280 (13%)
Query: 109 TRVREIKFILQIPAHKN---LVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKH-RKRRVF 164
T +REI + ++ N V + ++ +S L++V E ++ ++ + M +
Sbjct: 47 TAIREISLLKEVNDENNRSNCVRLLDILHAES--KLYLVFEFLDMDLKKYMDRISETGAT 104
Query: 165 SLPT--LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYV 222
SL ++ +Q++ G P+N+LI
Sbjct: 105 SLDPRLVQKFTYQLVNGVNFCHSRRIIHRDLKPQNLLIDKEGN----------------- 147
Query: 223 VKLADYGLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFS 281
+KLAD+GLAR YT + T WYR+PE+LL +YS +DIW+ GC+ E+ S
Sbjct: 148 LKLADFGLARSFGVPLRNYTHEIVTLWYRAPEVLLGSRHYSTGVDIWSVGCIFAEMIRRS 207
Query: 282 PLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRD 341
PLFPG E D+I++I +LG+P+ + W L Q FP + +
Sbjct: 208 PLFPGDSEIDEIFKIFQVLGTPNEEV---------W-PGVTLLQDYKSTFPRWKRMDLHK 257
Query: 342 VLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
V+PN + ED +++++ L ++P+ R +A Y +++
Sbjct: 258 VVPNGE-EDAIELLSAMLVYDPAHRISAKRALQQNYLRDF 296
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 97.4 bits (241), Expect = 7e-20
Identities = 72/272 (26%), Positives = 127/272 (46%), Gaps = 36/272 (13%)
Query: 112 REIKFILQIPAHKNLVTIYEMFIDDSLYH----LHIVMECMEQNIYQLMKHRKRRVFSLP 167
RE++ +L+ H+N++ + ++F D ++VM M ++ +LMKH K
Sbjct: 73 RELR-LLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEK---LGED 128
Query: 168 TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
++ +++Q+L G P N+ ++ ++ +K+ D
Sbjct: 129 RIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVN-----------------EDCELKILD 171
Query: 228 YGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
+GLAR + S T YV TRWYR+PE++L Y++ +DIW+ GC++ E+ T LF GS
Sbjct: 172 FGLARQAD--SEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGS 229
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQ 347
D DQ+ I+ + G+P + + + K L P +E K +L N
Sbjct: 230 DHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNNMKGL--------PELEKKDFASILTNAS 281
Query: 348 LEDLYDVVTSCLKWNPSERATANEICALPYFK 379
+++ L + +R TA E A PYF+
Sbjct: 282 -PLAVNLLEKMLVLDAEQRVTAGEALAHPYFE 312
>7298142 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 722
Score = 97.4 bits (241), Expect = 7e-20
Identities = 92/372 (24%), Positives = 151/372 (39%), Gaps = 54/372 (14%)
Query: 2 PALTLTTADSFIPPDVNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSAT 61
PA T T + D N I +I RY +++ +GKGSFG V A A
Sbjct: 168 PAPTANTTNLGYDDDNGNYKI-IEHDHIAFRYEILEVIGKGSFGQVIRALDHKTNTHVAI 226
Query: 62 QISSMYPETLMDQTLIRNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIP 121
+I L + N+ E ++K +++ L DYT R+
Sbjct: 227 KIIRNKKRFLNQAVVELNILDE---LREKDADGSHNVIHML----DYTYFRK-------- 271
Query: 122 AHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXX 181
HL I E M N+Y+L+K FS+ +R I+
Sbjct: 272 ------------------HLCITFELMSLNLYELIKKNNYNGFSMSLIRRFCNSIVKCLR 313
Query: 182 XXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYT 241
PENIL+ + +K+ D+G + +V+ +
Sbjct: 314 LLYKENIIHCDLKPENILLKQR---------------GSSSIKVIDFGSSCYVDRK--IY 356
Query: 242 TYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLG 301
TY+ +R+YRSPE++L Y +D+W+ GC++ EL T PLFPG +E +Q+ I+++LG
Sbjct: 357 TYIQSRFYRSPEVILGL-QYGTAIDMWSLGCILAELYTGFPLFPGENEVEQLACIMEVLG 415
Query: 302 SPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLY--DVVTSCL 359
P + + DS+ + + + + +D Y D + CL
Sbjct: 416 LPPKVLISVARRRRLFFDSRDAPRCITNTKGRKRSPGSKSLAHILHCQDRYFIDFLQRCL 475
Query: 360 KWNPSERATANE 371
+W+P+ER T +E
Sbjct: 476 EWDPAERMTPDE 487
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 97.1 bits (240), Expect = 9e-20
Identities = 76/272 (27%), Positives = 121/272 (43%), Gaps = 36/272 (13%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLP- 167
T +REIK + ++ H +++ + + F +LHIV E ME ++ ++ R R ++ P
Sbjct: 54 TALREIKLLKELK-HPHIIELIDAFPHKE--NLHIVFEFMETDLEAVI--RDRNLYLSPG 108
Query: 168 TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
++S L IL G P N+LI P N +KLAD
Sbjct: 109 DVKSYLQMILKGLEYCHGKWVLHRDMKPNNLLIGP-----------------NGQLKLAD 151
Query: 228 YGLARHVNNRS-PYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPG 286
+GLAR + +T V RWYR+PE+L Y +D+WA GC+ EL P G
Sbjct: 152 FGLARIFGSPGRKFTHQVFARWYRAPELLFGAKQYDGAVDVWAAGCIFAELLLRRPFLQG 211
Query: 287 SDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNP 346
+ + DQ+ +I G+P W D L + Y+F V ++R +LP
Sbjct: 212 NSDIDQLSKIFAAFGTPK---------ADQWPDMICLPDYVEYQF--VPAPSLRSLLPTV 260
Query: 347 QLEDLYDVVTSCLKWNPSERATANEICALPYF 378
ED D+++ ++P R + + YF
Sbjct: 261 S-EDALDLLSKMFTYDPKSRISIQQALKHRYF 291
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 96.7 bits (239), Expect = 1e-19
Identities = 95/395 (24%), Positives = 166/395 (41%), Gaps = 45/395 (11%)
Query: 18 NNPPFYIPLKNIDARYNVIQE--LGKGSFGSVTLAETMYDM-------NSSATQISSMYP 68
N+PP I ++I+ R ++ + L +G +TL ++D S ++I
Sbjct: 103 NHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKL 162
Query: 69 ETLMDQTLIRNVEQENWYYKKK----GIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHK 124
ET + + Y K +VA+K + T +RE+ + + H
Sbjct: 163 ETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLK-HA 221
Query: 125 NLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXX 184
N+VT++++ + L +V E +++++ Q + + ++ ++ LFQ+L G
Sbjct: 222 NIVTLHDIIHTEK--SLTLVFEYLDKDLKQYLDDCGN-IINMHNVKLFLFQLLRGLAYCH 278
Query: 185 XXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVN-NRSPYTTY 243
P+N+LI+ + +KLAD+GLAR + Y+
Sbjct: 279 RQKVLHRDLKPQNLLIN-----------------ERGELKLADFGLARAKSIPTKTYSNE 321
Query: 244 VSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
V T WYR P+ILL YS +D+W GC+ E+AT PLFPGS +Q+ I +LG+P
Sbjct: 322 VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTP 381
Query: 304 DHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNP 363
+W + Y +P + + P D D++T L++
Sbjct: 382 TEE---------TWPGILSNEEFKTYNYPKYRAEALLSHAPRLD-SDGADLLTKLLQFEG 431
Query: 364 SERATANEICALPYFKEYVMREASLAKTNNGTASK 398
R +A + P+F R L T + A K
Sbjct: 432 RNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALK 466
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 96.7 bits (239), Expect = 1e-19
Identities = 95/395 (24%), Positives = 166/395 (41%), Gaps = 45/395 (11%)
Query: 18 NNPPFYIPLKNIDARYNVIQE--LGKGSFGSVTLAETMYDM-------NSSATQISSMYP 68
N+PP I ++I+ R ++ + L +G +TL ++D S ++I
Sbjct: 55 NHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKL 114
Query: 69 ETLMDQTLIRNVEQENWYYKKK----GIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHK 124
ET + + Y K +VA+K + T +RE+ + + H
Sbjct: 115 ETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLK-HA 173
Query: 125 NLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXX 184
N+VT++++ + L +V E +++++ Q + + ++ ++ LFQ+L G
Sbjct: 174 NIVTLHDIIHTEK--SLTLVFEYLDKDLKQYLDDCGN-IINMHNVKLFLFQLLRGLAYCH 230
Query: 185 XXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVN-NRSPYTTY 243
P+N+LI+ + +KLAD+GLAR + Y+
Sbjct: 231 RQKVLHRDLKPQNLLIN-----------------ERGELKLADFGLARAKSIPTKTYSNE 273
Query: 244 VSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
V T WYR P+ILL YS +D+W GC+ E+AT PLFPGS +Q+ I +LG+P
Sbjct: 274 VVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTP 333
Query: 304 DHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNP 363
+W + Y +P + + P D D++T L++
Sbjct: 334 TEE---------TWPGILSNEEFKTYNYPKYRAEALLSHAPRLD-SDGADLLTKLLQFEG 383
Query: 364 SERATANEICALPYFKEYVMREASLAKTNNGTASK 398
R +A + P+F R L T + A K
Sbjct: 384 RNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALK 418
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 96.7 bits (239), Expect = 1e-19
Identities = 76/292 (26%), Positives = 137/292 (46%), Gaps = 38/292 (13%)
Query: 93 VAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTIYEMFID---DSLYHLHIVMECM 148
VAIK + N D R +RE+K + + H+N++ + ++ + S +++V E M
Sbjct: 58 VAIKKIHNVFENRVDALRTLRELKLLRHV-RHENVIALKDVMLPANRSSFKDVYLVYELM 116
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ +++Q++K + S + LFQ+L G P N+L++
Sbjct: 117 DTDLHQIIKSSQS--LSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNA------ 168
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTT-YVSTRWYRSPEILLRKGYYSKPLDI 267
N +K+ D+GLAR + T YV TRWYR+PE+LL Y +D+
Sbjct: 169 -----------NCDLKICDFGLARTSQGNEQFMTEYVVTRWYRAPELLLCCDNYGTSIDV 217
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQAL 327
W+ GC+ E+ P+FPG++ +Q+ I++++GS S ++D+ P +
Sbjct: 218 WSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGSQQES-------DIRFIDN-PKARRF 269
Query: 328 NYEFPYVEGKTIRDVLP--NPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
PY G + ++ P NP DL + L ++P++R + + PY
Sbjct: 270 IKSLPYSRGTHLSNLYPQANPLAIDL---LQRMLVFDPTKRISVTDALLHPY 318
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 96.3 bits (238), Expect = 2e-19
Identities = 66/266 (24%), Positives = 130/266 (48%), Gaps = 30/266 (11%)
Query: 93 VAIKTMMNRLPTL-HDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMEC 147
VA+K + ++ H RE++ +L+ H+N++ + ++F + +++V
Sbjct: 50 VAVKKLSRPFQSIIHAKRTYRELR-LLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHL 108
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
M ++ ++K +K + ++ +++QIL G P N+ ++
Sbjct: 109 MGADLNNIVKCQK---LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVN------ 159
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
++ +K+ D+GLARH ++ T YV+TRWYR+PEI+L +Y++ +DI
Sbjct: 160 -----------EDCELKILDFGLARHTDDEM--TGYVATRWYRAPEIMLNWMHYNQTVDI 206
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK--EHFGGSWLDSKPLYQ 325
W+ GC++ EL T LFPG+D DQ+ IL L+G+P + K +++ S
Sbjct: 207 WSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMP 266
Query: 326 ALNYEFPYVEGKTIRDVLPNPQLEDL 351
+N+ ++ + + P L D+
Sbjct: 267 KMNFANVFIGANPLGKLTIYPHLMDI 292
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 96.3 bits (238), Expect = 2e-19
Identities = 73/284 (25%), Positives = 135/284 (46%), Gaps = 36/284 (12%)
Query: 112 REIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLP 167
RE++ I+++ H N+V + F D LY L++V+E + + IY+ + + +P
Sbjct: 142 RELQ-IMRMLDHPNVVELKHSFFSTTEKDELY-LNLVLEYVPETIYRASRSYTKMNQHMP 199
Query: 168 TLRSILF--QIL-AGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
+ L+ QI A P+N+L++ + + VK
Sbjct: 200 LIYIQLYTYQICRAMNYLHQVVGVCHRDIKPQNLLVN----------------NVTHEVK 243
Query: 225 LADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
+ D+G A+ + P +Y+ +R+YR+PE++ Y+ +D+W+ GCV+ EL PLF
Sbjct: 244 ICDFGSAKMLIPGEPNISYICSRYYRAPELIFGATEYTSAIDMWSVGCVMAELFLGHPLF 303
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG DQ+ I+ +LG+P +E + P Y +++FP ++ + +
Sbjct: 304 PGETSVDQLVEIIKILGTP-----AREEI----KNMNPRYN--DFKFPQIKAQPWHKIFR 352
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASL 388
+ D+ + L+++P+ R TA E CA P+F + ASL
Sbjct: 353 RQVSPEAMDLASRLLQYSPNLRCTALEACAHPFFDDLRDPRASL 396
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 95.9 bits (237), Expect = 2e-19
Identities = 97/391 (24%), Positives = 162/391 (40%), Gaps = 93/391 (23%)
Query: 4 LTLTTADSFIPPDVNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQI 63
+TL + P DVN+ Y I +LG+GS+ +V E+ D +
Sbjct: 91 ITLPAKEEVTPQDVND------------LYKRIDKLGEGSYATVYKCESKLDGS------ 132
Query: 64 SSMYPETLMDQTLIRNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAH 123
IVA+K + + +T +RE + + H
Sbjct: 133 ----------------------------IVALKEIKLQFQEGLPFTAIREASLLRNL-RH 163
Query: 124 KNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTL--RSILFQILAGXX 181
N+V+++++F + L V E M+ + L K+ ++ V+ L ++ + +LFQ+L G
Sbjct: 164 ANIVSLHDIFYQH--HQLTFVFEYMKMD---LSKYLEQNVYGLDSIDIKLLLFQLLRGLD 218
Query: 182 XXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRS-PY 240
P+N+L L++D V+KLAD+GLAR + S Y
Sbjct: 219 FCHRKKILHRDLKPQNLL------------LDEDG-----VLKLADFGLARAKSVPSRTY 261
Query: 241 TTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDET------DQIW 294
+ V T WYR P++L+ YS LD+W GC+ E+ T + LFPGS ++ DQ+
Sbjct: 262 SHEVVTLWYRPPDVLMGSTDYSTSLDMWGVGCIFAEICTGAALFPGSKDSHYPGTKDQLD 321
Query: 295 RILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQ----LED 350
I + G+PD W + K L FP + + + NP L+
Sbjct: 322 MIFSIRGTPDEK---------KWPEVKTLPGYTPELFP--RYRELSFIAVNPMFTKILKT 370
Query: 351 LYDVVTSCLKWNPSERATANEICALPYFKEY 381
+++ L+ P R +A PYF +
Sbjct: 371 GQELLGMLLQLRPESRVSAASAMLHPYFASF 401
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 95.9 bits (237), Expect = 2e-19
Identities = 71/287 (24%), Positives = 137/287 (46%), Gaps = 31/287 (10%)
Query: 93 VAIKTMMNRLPTL-HDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMEC 147
VAIK + + H RE K ++++ HKN++ + F + +++VME
Sbjct: 50 VAIKKLSRPFQNVTHAKRAYREFK-LMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMEL 108
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
M+ N+ Q+++ + +L+Q+L G P NI++
Sbjct: 109 MDANLCQVIQMD----LDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKA----- 159
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
+ +K+ D+GLAR T YV TR+YR+PE++L GY ++ +DI
Sbjct: 160 ------------DCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGY-TENVDI 206
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQA 326
W+ GC++ E+ LFPG+D DQ +I++ LG+P S + + ++++++P Y
Sbjct: 207 WSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTG 266
Query: 327 LNYEFPYVEGKTIRDVLPNP--QLEDLYDVVTSCLKWNPSERATANE 371
+++ + +G D N + D ++++ L +P +R + +E
Sbjct: 267 YSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDE 313
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 95.5 bits (236), Expect = 3e-19
Identities = 79/273 (28%), Positives = 132/273 (47%), Gaps = 28/273 (10%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REIK +LQ H N+ TI E+ ++ S ++++ E + ++ L+ +++ ++ S
Sbjct: 226 TSIREIK-LLQSFDHPNVSTIKEIMVE-SQKTVYMIFEYADNDLSGLLLNKEVQI-SHSQ 282
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
+ + Q+L G NILI DN + +K+ D+
Sbjct: 283 CKHLFKQLLLGMEYLHDNKILHRDVKGSNILI--------------DNQGN---LKITDF 325
Query: 229 GLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSD 288
GLAR +N+R+ YT V T WYR PE+LL Y +D+W GC++VEL + +F GS+
Sbjct: 326 GLARKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSN 385
Query: 289 ETDQIWRILDLLGSPDHSING-KEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQ 347
E +QI I ++G+P +IN + W Q Y + E + VLP+ +
Sbjct: 386 ELEQIESIFKIMGTP--TINSWPTLYDMPWFFMIMPQQTTKYVNNFSE--KFKSVLPSSK 441
Query: 348 LEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
L + L ++ ++R +A E YFKE
Sbjct: 442 CLQL---AINLLCYDQTKRFSATEALQSDYFKE 471
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 95.5 bits (236), Expect = 3e-19
Identities = 72/294 (24%), Positives = 133/294 (44%), Gaps = 34/294 (11%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VA+K + R +L+ HKN++++ +F + +++VME M
Sbjct: 52 VAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELM 111
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q++ + +L+Q+L G P NI++
Sbjct: 112 DANLCQVIHME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 160
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +DIW
Sbjct: 161 ----------SDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGY-KENVDIW 209
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ EL +F G+D DQ ++++ LG+P K + ++++++P Y +
Sbjct: 210 SVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGI 269
Query: 328 NYE--FP--YVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
+E FP ++ RD + Q DL ++ L +P +R + +E PY
Sbjct: 270 KFEELFPDWIFPSESERDKIKTSQARDL---LSKMLVIDPDKRISVDEALRHPY 320
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 95.5 bits (236), Expect = 3e-19
Identities = 79/273 (28%), Positives = 123/273 (44%), Gaps = 34/273 (12%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLR 170
+REI + ++ HKN+V ++++ D L +V E +Q++ + + ++
Sbjct: 49 LREICLLKELK-HKNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDL-DPEIVK 104
Query: 171 SILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGL 230
S LFQ+L G P+N+LI+ N +KLAD+GL
Sbjct: 105 SFLFQLLKGLGFCHSRNVLHRDLKPQNLLINR-----------------NGELKLADFGL 147
Query: 231 ARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFS-PLFPGSD 288
AR Y+ V T WYR P++L YS +D+W+ GC+ ELA PLFPG+D
Sbjct: 148 ARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGND 207
Query: 289 ETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQL 348
DQ+ RI LLG+P W L Y Y ++ +V+P
Sbjct: 208 VDDQLKRIFRLLGTPTEE---------QWPSMTKLPDYKPYPM-YPATTSLVNVVPKLNA 257
Query: 349 EDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
D++ + LK NP +R +A E PYF ++
Sbjct: 258 TG-RDLLQNLLKCNPVQRISAEEALQHPYFSDF 289
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 95.5 bits (236), Expect = 3e-19
Identities = 76/299 (25%), Positives = 136/299 (45%), Gaps = 48/299 (16%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDS----LYHLHIVMECM 148
VAIK + + R +L+ H+N++ + ++F S Y ++VM M
Sbjct: 51 VAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFM 110
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ ++ ++M FS ++ +++Q+L G P N+ ++
Sbjct: 111 QTDLQKIMGME----FSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVN------- 159
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
++ +K+ D+GLARH + + T YV TRWYR+PE++L +Y++ +DIW
Sbjct: 160 ----------EDCELKILDFGLARHAD--AEMTGYVVTRWYRAPEVILSWMHYNQTVDIW 207
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPD----HSINGKEHFGGSWLDSKPLY 324
+ GC++ E+ T LF G D DQ+ +IL + G P +N K +K
Sbjct: 208 SVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKA--------AKSYI 259
Query: 325 QALNYEFPYVEGKTIRDVLP--NPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
Q+L P K + P +PQ DL + L+ + +R TA + P+F+ +
Sbjct: 260 QSL----PQTPRKDFTQLFPRASPQAADLLE---KMLELDVDKRLTAAQALTHPFFEPF 311
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 95.5 bits (236), Expect = 3e-19
Identities = 72/294 (24%), Positives = 133/294 (44%), Gaps = 34/294 (11%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VA+K + R +L+ HKN++++ +F + +++VME M
Sbjct: 52 VAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELM 111
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q++ + +L+Q+L G P NI++
Sbjct: 112 DANLCQVIHME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 160
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +DIW
Sbjct: 161 ----------SDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGY-KENVDIW 209
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ EL +F G+D DQ ++++ LG+P K + ++++++P Y +
Sbjct: 210 SVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGI 269
Query: 328 NYE--FP--YVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
+E FP ++ RD + Q DL ++ L +P +R + +E PY
Sbjct: 270 KFEELFPDWIFPSESERDKIKTSQARDL---LSKMLVIDPDKRISVDEALRHPY 320
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 95.5 bits (236), Expect = 3e-19
Identities = 72/294 (24%), Positives = 133/294 (44%), Gaps = 34/294 (11%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VA+K + R +L+ HKN++++ +F + +++VME M
Sbjct: 52 VAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELM 111
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q++ + +L+Q+L G P NI++
Sbjct: 112 DANLCQVIHME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 160
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +DIW
Sbjct: 161 ----------SDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGY-KENVDIW 209
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ EL +F G+D DQ ++++ LG+P K + ++++++P Y +
Sbjct: 210 SVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGI 269
Query: 328 NYE--FP--YVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
+E FP ++ RD + Q DL ++ L +P +R + +E PY
Sbjct: 270 KFEELFPDWIFPSESERDKIKTSQARDL---LSKMLVIDPDKRISVDEALRHPY 320
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 95.5 bits (236), Expect = 3e-19
Identities = 60/216 (27%), Positives = 113/216 (51%), Gaps = 28/216 (12%)
Query: 93 VAIKTMMNRLPTL-HDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMEC 147
VA+K + ++ H RE++ +L+ H+N++ + ++F + +++V
Sbjct: 50 VAVKKLSRPFQSIIHAKRTYRELR-LLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHL 108
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
M ++ ++K +K + ++ +++QIL G P N+ ++
Sbjct: 109 MGADLNNIVKCQK---LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVN------ 159
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
++ +K+ D+GLARH ++ T YV+TRWYR+PEI+L +Y++ +DI
Sbjct: 160 -----------EDCELKILDFGLARHTDDEM--TGYVATRWYRAPEIMLNWMHYNQTVDI 206
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
W+ GC++ EL T LFPG+D DQ+ IL L+G+P
Sbjct: 207 WSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTP 242
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 95.5 bits (236), Expect = 3e-19
Identities = 86/356 (24%), Positives = 152/356 (42%), Gaps = 69/356 (19%)
Query: 33 YNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKGI 92
Y ++ ++G+G++G V A ++++ E Q ++ V EN +K+G
Sbjct: 311 YTMLDQIGEGTYGQVYKA------------VNNLTGE----QVALKRVRLEN---EKEGF 351
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDD--------SLYHLHIV 144
T +REIK + Q+ HKN+V + ++ IDD + + ++V
Sbjct: 352 --------------PITAIREIKILRQLH-HKNIVRLMDIVIDDISMDELKRTRANFYLV 396
Query: 145 MECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH 204
E ++ ++ L++ ++ F+ + S+ Q+L G NIL++
Sbjct: 397 FEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKG 456
Query: 205 RYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSK 263
+K+AD GLAR S YT V T WYR PE+LL Y
Sbjct: 457 E-----------------LKIADLGLARLWEKESRLYTNRVITLWYRPPELLLGDERYGP 499
Query: 264 PLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPL 323
+D+W+ GC++ EL T PLF G++E Q+ I + GSP+ +W + L
Sbjct: 500 AIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVD---------NWPELTEL 550
Query: 324 YQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
+ + IR+ + + D++ L NP +R +A E P+ +
Sbjct: 551 VGWNTFRMKRTYQRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKEALNHPWIR 606
>At3g14720 [T] KOG0660 Mitogen-activated protein kinase
Length = 586
Score = 95.5 bits (236), Expect = 3e-19
Identities = 95/361 (26%), Positives = 155/361 (42%), Gaps = 80/361 (22%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY +++ +GKGS+G V A I + E
Sbjct: 12 RYRILEVIGKGSYGVVCAA------------IDTQTGEK--------------------- 38
Query: 92 IVAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFIDDS---LYHLHIVMEC 147
VAIK + + + D R+ RE+K +L++ H ++V I + + S +++V E
Sbjct: 39 -VAIKKINDVFEHVSDALRILREVK-LLRLLRHPDIVEIKSIMLPPSKREFKDIYVVFEL 96
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
ME +++Q++K + + L+Q+L P+NIL +
Sbjct: 97 MESDLHQVIKANDD--LTREHHQFFLYQMLRALKYMHTANVYHRDLKPKNILANA----- 149
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSP----YTTYVSTRWYRSPEIL-LRKGYYS 262
N +K+ D+GLAR N +P +T YV+TRWYR+PE+ Y+
Sbjct: 150 ------------NCKLKVCDFGLARVSFNDTPTTVFWTDYVATRWYRAPELCGSFCSKYT 197
Query: 263 KPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP-DHSING-KEHFGGSWLDS 320
+DIW+ GC+ E+ T PLFPG Q+ I DLLG+P +I G + +L+
Sbjct: 198 PAIDIWSIGCIFAEVLTGKPLFPGKSVVHQLDLITDLLGTPKSETIAGVRNEKARKYLNE 257
Query: 321 --KPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
K + +FP + +R ++ L ++P +R TA E A PYF
Sbjct: 258 MRKKNLVPFSQKFPNADPLALR-------------LLQRLLAFDPKDRPTAAEALADPYF 304
Query: 379 K 379
K
Sbjct: 305 K 305
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 95.1 bits (235), Expect = 3e-19
Identities = 83/279 (29%), Positives = 132/279 (46%), Gaps = 46/279 (16%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T VRE+K ILQ HKN+V + E+ ++ S +++V E M+ ++ ++ + + F+
Sbjct: 320 TTVREVK-ILQRLRHKNIVRLLEIMVEKS--SVYMVFEYMDHDLTGVLLNSQLH-FTPGN 375
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
++ + QI NIL++ +N +K AD+
Sbjct: 376 IKHLSKQIFEALAYLHHRGVLHRDIKGSNILLN-----------------NNGDLKFADF 418
Query: 229 GLAR-HVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPG 286
GLAR + +++S YT V T W+R PE+LL + Y +DIW+ GC+V+EL T P F G
Sbjct: 419 GLARFNTSSKSANYTNRVITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQG 478
Query: 287 SDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSK--PLYQALNYEFPYVEGK-----TI 339
DE Q+ I D++G+PD SW + K P Y+ L P E K T
Sbjct: 479 RDEISQLEVIYDMMGTPDVH---------SWPEVKNLPWYELLK---PVEEKKSRFVETF 526
Query: 340 RDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
+++L + D+ L NP R +A+E YF
Sbjct: 527 KEILSPAAI----DLCQKLLALNPFCRPSAHETLMHEYF 561
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 95.1 bits (235), Expect = 3e-19
Identities = 92/355 (25%), Positives = 152/355 (41%), Gaps = 70/355 (19%)
Query: 29 IDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYK 88
I RY+ +Q +G G+FG V S+ Q++ M
Sbjct: 16 ITTRYSDLQPIGMGAFGLVC---------SAKDQLTGMN--------------------- 45
Query: 89 KKGIVAIKTMMNRL--PTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVME 146
VA+K +M P L T RE+K + + H+N++++ ++FI ++ V E
Sbjct: 46 ----VAVKKIMKPFSTPVLAKRT-YRELKLLKHL-RHENIISLSDIFISP-FEDIYFVTE 98
Query: 147 CMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRY 206
+ ++++L+ R ++ L+QIL G P NILI+
Sbjct: 99 LLGTDLHRLLTSRP---LETQFIQYFLYQILRGLKFVHSAGVIHRDLKPSNILIN----- 150
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
+N +K+ D+GLAR + + T YVSTR+YR+PEI+L Y+ +D
Sbjct: 151 ------------ENCDLKICDFGLARIQDPQM--TGYVSTRYYRAPEIMLTWQKYNVEVD 196
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQA 326
IW+ GC+ E+ PLFPG D +Q I +LLG+P + + SK +
Sbjct: 197 IWSAGCIFAEMIEGKPLFPGRDHVNQFSIITELLGTPPMEVI-------ETICSKNTLRF 249
Query: 327 LNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
+ P E + N D D++ L ++P +R +A + A Y Y
Sbjct: 250 VQ-SLPQKEKVPFAEKFKNAD-PDAIDLLEKMLVFDPRKRISAADALAHNYLAPY 302
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 95.1 bits (235), Expect = 3e-19
Identities = 67/278 (24%), Positives = 125/278 (44%), Gaps = 34/278 (12%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEM---FIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFS 165
T +REI + + ++V + ++ + L++V E M+ ++ + ++ + +
Sbjct: 57 TTLREISILRMLARDPHVVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFIRSFRSTGKN 116
Query: 166 LPT--LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVV 223
+PT ++S+++Q+ G P N+L+ P +
Sbjct: 117 IPTQTIKSLMYQLCKGMAFCHGHGILHRDLKPHNLLMDPK----------------TMRL 160
Query: 224 KLADYGLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSP 282
K+AD GLAR YT + T WYR+PE+LL +YS +D+W+ GC+ EL T
Sbjct: 161 KIADLGLARAFTLPMKKYTHEILTLWYRAPEVLLGATHYSTAVDMWSVGCIFAELVTNQA 220
Query: 283 LFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDV 342
+F G E Q+ I L G+P+ + +W +E+P + T+
Sbjct: 221 IFQGDSELQQLLHIFKLFGTPNEEMWPGVSTLKNW-----------HEYPQWKPSTLSSA 269
Query: 343 LPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+PN E D+++ L++ P++R +A PYF +
Sbjct: 270 VPNLD-EAGVDLLSKMLQYEPAKRISAKMAMEHPYFDD 306
>7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 387
Score = 95.1 bits (235), Expect = 3e-19
Identities = 73/271 (26%), Positives = 125/271 (45%), Gaps = 34/271 (12%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLR 170
+REI + Q H+N+V + E+ + SL + +VM+ EQ++ ++ + + F+ ++
Sbjct: 98 LREIMILKQCH-HENIVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQP-FTESEVK 155
Query: 171 SILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGL 230
I Q+L N+L++ D +K+AD+GL
Sbjct: 156 CITLQVLKALKYLHSRFMIHRDLKVSNLLMT-----------------DKGCIKVADFGL 198
Query: 231 ARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDE 289
AR +N P T + T WYR+PE+LL ++ +D+WA+GC++ EL PL PG+ E
Sbjct: 199 ARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGELLLGKPLLPGNSE 258
Query: 290 TDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQL- 348
Q+ I+DLLG+P SI W L N+ + + ++ P +
Sbjct: 259 IAQLDMIIDLLGAPSESI---------WPGFADLPAVQNFT---LSQQPYNNLTPKFHMI 306
Query: 349 -EDLYDVVTSCLKWNPSERATANEICALPYF 378
+ +++ +NP RATA E YF
Sbjct: 307 GQSGRNLLNILFIYNPKTRATAEECLKSKYF 337
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 94.7 bits (234), Expect = 5e-19
Identities = 75/299 (25%), Positives = 141/299 (47%), Gaps = 47/299 (15%)
Query: 93 VAIKTMMNRLPTL-HDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMEC 147
VA+K + +L H RE++ + + H+N++ + ++F + +++V
Sbjct: 50 VAVKKLSRPFQSLIHARRTYRELRLLKHLK-HENVIGLLDVFTPATSIEDFSEVYLVTTL 108
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
M ++ ++K + S ++ +++Q+L G P N+ ++
Sbjct: 109 MGADLNNIVKCQ---ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVN------ 159
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
++ +++ D+GLAR + T YV+TRWYR+PEI+L +Y++ +DI
Sbjct: 160 -----------EDCELRILDFGLARQADEEM--TGYVATRWYRAPEIMLNWMHYNQTVDI 206
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK---EHFGGSWLDSKPLY 324
W+ GC++ EL LFPGSD DQ+ RI++++G+P + K EH ++
Sbjct: 207 WSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEH-------ARTYI 259
Query: 325 QALNYEFPYVEGKTIRDVL--PNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
Q+L P + K + + NP DL + L + +R +A E A YF +Y
Sbjct: 260 QSL----PPMPQKDLSSIFRGANPLAIDL---LGRMLVLDSDQRVSAAEALAHAYFSQY 311
>Hs13430860 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1198
Score = 94.7 bits (234), Expect = 5e-19
Identities = 70/224 (31%), Positives = 107/224 (47%), Gaps = 25/224 (11%)
Query: 85 WYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHK----NLVTIYEMFIDDSLYH 140
W IVAIK + NR P+ ++ E+ + ++ N V YE F + H
Sbjct: 217 WKRGTNEIVAIKILKNR-PSYARQGQI-EVSILARLSTESADDYNFVRAYECFQHKN--H 272
Query: 141 LHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENI-L 199
+V E +EQN+Y +K K L +R +L Q+ PENI L
Sbjct: 273 TCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIML 332
Query: 200 ISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKG 259
+ PS + Y VK+ D+G A HV+ ++ +TY+ +R+YR+PEI+L
Sbjct: 333 VDPSRQ--------------PYRVKVIDFGSASHVS-KAVCSTYLQSRYYRAPEIILGLP 377
Query: 260 YYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
+ + +D+W+ GCV+ EL PL+PG+ E DQI I G P
Sbjct: 378 F-CEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLP 420
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 94.7 bits (234), Expect = 5e-19
Identities = 63/234 (26%), Positives = 112/234 (46%), Gaps = 35/234 (14%)
Query: 88 KKKGIVAIKTMMNRLPTLHDYTR--VREIKFILQIPAHKNLVTIYEMFIDDSLY--HLHI 143
+ K VAIK + R T H + +RE++ + ++ H+N++ + +MF + + +++
Sbjct: 78 RNKKQVAIKKIP-RAFTAHTLAKRSLREVRILREL-LHENIIAVLDMFTAEGAHGKDIYL 135
Query: 144 VMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPS 203
VM+ ME +++Q++ R+ + +Q+L G P N+L++
Sbjct: 136 VMDLMETDLHQIL--HSRQTLMEQHFQYFFYQLLRGLKYLHSAGIIHRDLKPSNLLLN-- 191
Query: 204 HRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPY----------TTYVSTRWYRSPE 253
+ ++++AD+G+AR + S T YVSTRWYR+PE
Sbjct: 192 ---------------GDCLLRIADFGMARAYASASTVRDDANVGGHMTQYVSTRWYRAPE 236
Query: 254 ILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI 307
IL Y +D+W+ GC+ E+ LFPG D QI I+ LGSP+ +
Sbjct: 237 ILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVYYLGSPEEEV 290
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 94.7 bits (234), Expect = 5e-19
Identities = 69/246 (28%), Positives = 111/246 (45%), Gaps = 37/246 (15%)
Query: 140 HLHIVMECMEQNIYQLM-KHRKR---RVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXP 195
+L++V E ++ ++ + + HRK R ++ +FQ+ G P
Sbjct: 88 NLYLVFEYLDTDLKKFIDSHRKGSNPRPLEASLVQRFMFQLFKGVAHCHSHGVLHRDLKP 147
Query: 196 ENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVN-NRSPYTTYVSTRWYRSPEI 254
+N+L+ D ++K+AD GL+R YT + T WYR+PE+
Sbjct: 148 QNLLLD----------------KDKGILKIADLGLSRAFTVPLKAYTHEIVTLWYRAPEV 191
Query: 255 LLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFG 314
LL +YS +DIW+ GC+ E+ LFPG E Q+ I LLG+P
Sbjct: 192 LLGSTHYSTAVDIWSVGCIFAEMIRRQALFPGDSEFQQLLHIFRLLGTPTEQ-------- 243
Query: 315 GSWLDSKPLYQALN--YEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
W P AL + +P E + + +P+ E + D++T LK+NP+ER +A
Sbjct: 244 -QW----PGVMALRDWHVYPKWEPQDLSRAVPSLSPEGI-DLLTQMLKYNPAERISAKAA 297
Query: 373 CALPYF 378
PYF
Sbjct: 298 LDHPYF 303
>At1g18150 [T] KOG0660 Mitogen-activated protein kinase
Length = 589
Score = 94.7 bits (234), Expect = 5e-19
Identities = 83/301 (27%), Positives = 143/301 (46%), Gaps = 50/301 (16%)
Query: 93 VAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFIDDS---LYHLHIVMECM 148
VAIK + + + D TR+ REIK +L++ H ++V I + + S +++V E M
Sbjct: 130 VAIKKINDVFEHVSDATRILREIK-LLRLLRHPDVVEIKHIMLPPSRREFRDIYVVFELM 188
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
E +++Q++K + + L+Q+L G P+NIL + +
Sbjct: 189 ESDLHQVIKANDD--LTPEHYQFFLYQLLRGLKYVHAANVFHRDLKPKNILANADCK--- 243
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSP----YTTYVSTRWYRSPEILLRKGYYSK- 263
+K+ D+GLAR N +P +T YV+TRWYR+PE+ ++SK
Sbjct: 244 --------------LKICDFGLARVSFNDAPTAIFWTDYVATRWYRAPELC--GSFFSKY 287
Query: 264 --PLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS-PDHSING-KEHFGGSWLD 319
+DIW+ GC+ E+ PLFPG + Q+ + D LG+ P SI+ + +L
Sbjct: 288 TPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDLMTDFLGTPPPESISRIRNEKARRYLS 347
Query: 320 SKPLYQAL--NYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
S Q + +++FP + +R ++ L ++P +RA+A + A PY
Sbjct: 348 SMRKKQPVPFSHKFPKADPLALR-------------LLERLLAFDPKDRASAEDALADPY 394
Query: 378 F 378
F
Sbjct: 395 F 395
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 94.4 bits (233), Expect = 6e-19
Identities = 69/287 (24%), Positives = 135/287 (46%), Gaps = 29/287 (10%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFI----DDSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
+RE+K + + H N+V +++ I + +L +++ E ME ++ Q+++ +R
Sbjct: 70 LRELKLLRHLRGHPNIVWLFDTDIVFYPNGALNGVYLYEELMECDLSQIIRSEQR--LED 127
Query: 167 PTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLA 226
+S ++QIL P+N+L++ + + +YS+N+ V
Sbjct: 128 AHFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKV--- 184
Query: 227 DYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPG 286
N Y+++ WY++PEILL +K +DIW+ GC++ EL P+F G
Sbjct: 185 ---------NDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPMFEG 235
Query: 287 SDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNP 346
D D + IL +LG+P + + S+ +Y + ++F + G++ +LP
Sbjct: 236 KDYVDHLNHILQILGTPPEETLQE-------IASQKVYNYI-FQFGNIPGRSFESILPGA 287
Query: 347 QLEDLYDVVTSCLKWNPSERATANEICALPYFKEY--VMREASLAKT 391
E L +++ L+++P +R T + PY + + E S KT
Sbjct: 288 NPEAL-ELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEEFSCQKT 333
>YDL079c [G] KOG0658 Glycogen synthase kinase-3
Length = 501
Score = 94.0 bits (232), Expect = 8e-19
Identities = 66/270 (24%), Positives = 124/270 (45%), Gaps = 36/270 (13%)
Query: 118 LQIPAHKNLVTI----YEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT--LRS 171
+++ H N V + YE +D +Y L++V++ M Q++YQ ++H +P ++
Sbjct: 209 MKMLCHPNTVGLQYYFYEKDEEDEVY-LNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKF 267
Query: 172 ILFQILAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGL 230
+Q+ P+N+L+ P+ + K+ D+G
Sbjct: 268 YAYQLFKALNYLHNVPRICHRDIKPQNLLVDPT----------------TFSFKICDFGS 311
Query: 231 ARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDET 290
A+ + P +Y+ +R+YR+PE++ YS +D+W+ CV+ EL PLF G
Sbjct: 312 AKCLKPDQPNVSYICSRYYRAPELMFGATNYSNQVDVWSSACVIAELLLGKPLFSGESGI 371
Query: 291 DQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLED 350
DQ+ I+ ++G P K+ G P Y+ ++ FP ++ T+ ++ + D
Sbjct: 372 DQLVEIIKIMGIPT-----KDEISG----MNPNYE--DHVFPNIKPITLAEIF-KAEDPD 419
Query: 351 LYDVVTSCLKWNPSERATANEICALPYFKE 380
D++T LK++P ER + YF E
Sbjct: 420 TLDLLTKTLKYHPCERLVPLQCLLSSYFDE 449
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 94.0 bits (232), Expect = 8e-19
Identities = 64/265 (24%), Positives = 121/265 (45%), Gaps = 35/265 (13%)
Query: 123 HKNLVTIYEMFID----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTL--RSILFQI 176
H N+V++ F D LY L++V+E + + +++++KH + +P + + +QI
Sbjct: 119 HPNVVSLKHCFFSTTEKDELY-LNLVLEYVPETVHRVIKHYNKLNQRMPLIYVKLYTYQI 177
Query: 177 LAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVN 235
P+N+L++P + VKL D+G A+ +
Sbjct: 178 FRALSYIHRCIGVCHRDIKPQNLLVNPH----------------THQVKLCDFGSAKVLV 221
Query: 236 NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWR 295
P +Y+ +R+YR+PE++ Y+ +D+W+ GCV+ EL PLFPG DQ+
Sbjct: 222 KGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVE 281
Query: 296 ILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVV 355
I+ +LG+P P Y ++FP ++ + + D+V
Sbjct: 282 IIKVLGTPTRE---------EIKCMNPNY--TEFKFPQIKAHPWHKIFHKRMPPEAVDLV 330
Query: 356 TSCLKWNPSERATANEICALPYFKE 380
+ L+++P+ R+ A + P+F E
Sbjct: 331 SRLLQYSPNLRSAALDTLVHPFFDE 355
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 94.0 bits (232), Expect = 8e-19
Identities = 68/265 (25%), Positives = 120/265 (44%), Gaps = 37/265 (13%)
Query: 123 HKNLVTIYEMFID----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTL--RSILFQI 176
H N+V++ F D LY L++V+E + + +Y++ KH R +P + + +QI
Sbjct: 124 HPNVVSLKHCFFSTTEKDELY-LNLVLEYVPETVYRVSKHYSRANQRMPIIYVKLYTYQI 182
Query: 177 LAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVN 235
P+N+L++P + VKL D+G A+ +
Sbjct: 183 CRALAYIHGGVGVCHRDIKPQNLLVNPH----------------THQVKLCDFGSAKVLV 226
Query: 236 NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWR 295
P +Y+ +R+YR+PE++ Y+ +DIW+ GCV+ EL PLFPG DQ+
Sbjct: 227 KGEPNISYICSRYYRAPELIFGATEYTTTIDIWSAGCVLAELLLGQPLFPGESGVDQLVE 286
Query: 296 ILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVV 355
I+ +LG+P P Y ++FP ++ + + D+V
Sbjct: 287 IIKVLGTPTRE---------EIKCMNPNY--TEFKFPQIKAHPWHKIFHKRTPPEAVDLV 335
Query: 356 TSCLKWNPSERATANEICALPYFKE 380
+ L+++P+ R+TA P+F E
Sbjct: 336 SRLLQYSPNLRSTA--AIVHPFFDE 358
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 94.0 bits (232), Expect = 8e-19
Identities = 60/198 (30%), Positives = 101/198 (50%), Gaps = 23/198 (11%)
Query: 111 VREIKFILQIPA--HKNLVTIYEM--FID-DSLYHLHIVMECMEQNIYQLMKHRKRRVFS 165
+REI + Q+ A H N+V +YE+ F++ D + +V E +EQ++ L+ + S
Sbjct: 71 LREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMS 130
Query: 166 LPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
PT++ + ++L G P+N+L+S +K+
Sbjct: 131 PPTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGH-----------------LKI 173
Query: 226 ADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFP 285
AD+GLA+ + T+ V T WYR+PE+LL + Y S +DIW+ C++ E+ LFP
Sbjct: 174 ADFGLAKTYGSEMKLTSVVVTLWYRAPEVLLAQPYNST-VDIWSAACIIFEMFNRRALFP 232
Query: 286 GSDETDQIWRILDLLGSP 303
G+ E +Q+ RI +L G P
Sbjct: 233 GTSEKNQLDRIFELTGRP 250
>Hs20550209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 520
Score = 93.6 bits (231), Expect = 1e-18
Identities = 90/358 (25%), Positives = 149/358 (41%), Gaps = 63/358 (17%)
Query: 22 FYIPL--KNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRN 79
FY+ + +I RY V++ +GKGSFG V +D
Sbjct: 91 FYLKVLHDHIAYRYEVLETIGKGSFGQVAKC---------------------LD------ 123
Query: 80 VEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLY 139
+K +VA+K + N+ H + E+K + + T + + D Y
Sbjct: 124 -------HKNNELVALKIIRNK-KRFHQQA-LMELKILEALRKKDKDNTYNVVHMKDFFY 174
Query: 140 ---HLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPE 196
H I E + N+Y+LMK+ + FSL +R +L PE
Sbjct: 175 FRNHFCITFELLGINLYELMKNNNFQGFSLSIVRRFTLSVLKCLQMLSVEKIIHCDLKPE 234
Query: 197 NILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILL 256
NI++ + VK+ D+G + + + + TY+ +R+YRSPE++L
Sbjct: 235 NIVLYQKGQAS---------------VKVIDFGSSCYEHQK--VYTYIQSRFYRSPEVIL 277
Query: 257 RKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGS 316
Y +D+W+ GC+ EL T PLFPG +E +Q+ I+++LG P +
Sbjct: 278 GHPY-DVAIDMWSLGCITAELYTGYPLFPGENEVEQLACIMEVLGLPPAGFIQTASRRQT 336
Query: 317 WLDSKPLYQALNY---EFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANE 371
+ DSK + + + Y + K + VL L D + CL W PS R T ++
Sbjct: 337 FFDSKGFPKNITNNRGKKRYPDSKDLTMVLKTYDTSFL-DFLRRCLVWEPSLRMTPDQ 393
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 93.6 bits (231), Expect = 1e-18
Identities = 86/360 (23%), Positives = 160/360 (43%), Gaps = 73/360 (20%)
Query: 26 LKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENW 85
L ID +Y I+ +G+G++G V SS+ ET
Sbjct: 25 LFEIDTKYVPIKPIGRGAYGVVC---------------SSINSET--------------- 54
Query: 86 YYKKKGIVAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTIYEMFIDDSLYH---L 141
VAIK + N D R +RE+K + + H+N++++ ++ + Y +
Sbjct: 55 ----NERVAIKKIHNVFENRIDALRTLRELKLLRHV-RHENVISLKDVMLPTHRYSFRDV 109
Query: 142 HIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILIS 201
++V E M+ ++ Q++K + S + LFQ+L G P N+L++
Sbjct: 110 YLVYELMDSDLNQIIKSSQS--LSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVN 167
Query: 202 PSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYY 261
N +K+ D+GLAR T YV TRWYR+PE+LL Y
Sbjct: 168 A-----------------NCDLKICDFGLARTYEQFM--TEYVVTRWYRAPELLLCCDNY 208
Query: 262 SKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSK 321
+D+W+ GC+ E+ P+FPG++ +Q+ I++++GS ++ + ++D++
Sbjct: 209 GTSIDVWSVGCIFAEILGRKPIFPGTECLNQLKLIINVVGS-------QQDWDLQFIDNQ 261
Query: 322 PLYQALNYEFPYVEGKTIRDVLP--NPQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
+ + P+ +G + P NP DL + L ++P++R + ++ PY +
Sbjct: 262 KARRFIK-SLPFSKGTHFSHIYPHANPLAIDL---LQRMLVFDPTKRISVSDALLHPYME 317
>At2g01450 [T] KOG0660 Mitogen-activated protein kinase
Length = 516
Score = 93.6 bits (231), Expect = 1e-18
Identities = 89/364 (24%), Positives = 153/364 (41%), Gaps = 84/364 (23%)
Query: 31 ARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKK 90
++Y + + +GKGS+G V AE P T
Sbjct: 14 SQYQIQEVVGKGSYGVVASAEC---------------PHT-------------------G 39
Query: 91 GIVAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFIDD---SLYHLHIVME 146
G VAIK M N + D R+ REIK +L++ H ++V I + + +++V E
Sbjct: 40 GKVAIKKMTNVFEHVSDAIRILREIK-LLRLLRHPDIVEIKHIMLPPCRKEFKDIYVVFE 98
Query: 147 CMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRY 206
ME +++ ++K + + L+Q+L G P+NIL + +
Sbjct: 99 LMESDLHHVLKVNDD--LTPQHHQFFLYQLLRGLKFMHSAHVFHRDLKPKNILANADCK- 155
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSP----YTTYVSTRWYRSPEILLR-KGYY 261
+K+ D GLAR SP +T YV+TRWYR+PE+ Y
Sbjct: 156 ----------------IKICDLGLARVSFTDSPSAVFWTDYVATRWYRAPELCGSFYSNY 199
Query: 262 SKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK------EHFGG 315
+ +D+W+ GC+ E+ T PLFPG + Q+ + DLLG+P + + G
Sbjct: 200 TPAIDMWSVGCIFAEMLTGKPLFPGKNVVHQLELVTDLLGTPSPITLSRIRNEKARKYLG 259
Query: 316 SWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICAL 375
+ P+ ++FP ++ ++ ++ + ++P +R +A E A
Sbjct: 260 NMRRKDPV--PFTHKFPNIDPVALK-------------LLQRLIAFDPKDRPSAEEALAD 304
Query: 376 PYFK 379
PYF+
Sbjct: 305 PYFQ 308
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 93.2 bits (230), Expect = 1e-18
Identities = 76/302 (25%), Positives = 143/302 (47%), Gaps = 45/302 (14%)
Query: 93 VAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTIYEMFIDDSLY----HLHIVMEC 147
VAIK + N + + R +RE+K IL+ H N++ I ++ Y +++V++
Sbjct: 81 VAIKKIPNAFDVVTNAKRTLRELK-ILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDL 139
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
ME +++Q++ + +L +R L+Q+L G P N+L++
Sbjct: 140 MESDLHQII--HSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVN------ 191
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHV-----NNRSPYTTYVSTRWYRSPEILLRKGYYS 262
+N +K+ D+G+AR + ++ T YV+TRWYR+PE++L Y+
Sbjct: 192 -----------ENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 240
Query: 263 KPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI---NGKEHFGGSWLD 319
+ +D+W+ GC+ E+ LFPG + Q+ I+ +LG+P ++ G E +++
Sbjct: 241 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERV-RAYIQ 299
Query: 320 SKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
S P Q + +E Y P + L ++ L++ PS R +A P+
Sbjct: 300 SLPPRQPVPWETVY----------PGADRQAL-SLLGRMLRFEPSARISAAAALRHPFLA 348
Query: 380 EY 381
+Y
Sbjct: 349 KY 350
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 93.2 bits (230), Expect = 1e-18
Identities = 76/302 (25%), Positives = 143/302 (47%), Gaps = 45/302 (14%)
Query: 93 VAIKTMMNRLPTLHDYTR-VREIKFILQIPAHKNLVTIYEMFIDDSLY----HLHIVMEC 147
VAIK + N + + R +RE+K IL+ H N++ I ++ Y +++V++
Sbjct: 81 VAIKKIPNAFDVVTNAKRTLRELK-ILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDL 139
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
ME +++Q++ + +L +R L+Q+L G P N+L++
Sbjct: 140 MESDLHQII--HSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVN------ 191
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHV-----NNRSPYTTYVSTRWYRSPEILLRKGYYS 262
+N +K+ D+G+AR + ++ T YV+TRWYR+PE++L Y+
Sbjct: 192 -----------ENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 240
Query: 263 KPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI---NGKEHFGGSWLD 319
+ +D+W+ GC+ E+ LFPG + Q+ I+ +LG+P ++ G E +++
Sbjct: 241 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERV-RAYIQ 299
Query: 320 SKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
S P Q + +E Y P + L ++ L++ PS R +A P+
Sbjct: 300 SLPPRQPVPWETVY----------PGADRQAL-SLLGRMLRFEPSARISAAAALRHPFLA 348
Query: 380 EY 381
+Y
Sbjct: 349 KY 350
>At1g73670 [T] KOG0660 Mitogen-activated protein kinase
Length = 576
Score = 93.2 bits (230), Expect = 1e-18
Identities = 80/303 (26%), Positives = 139/303 (45%), Gaps = 54/303 (17%)
Query: 93 VAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFIDDS---LYHLHIVMECM 148
VAIK + + + D TR+ REIK +L++ H ++V I + + S +++V E M
Sbjct: 116 VAIKKINDVFDHISDATRILREIK-LLRLLLHPDVVEIKHIMLPPSRREFRDVYVVFELM 174
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
E +++Q++K + + L+Q+L G P+NIL + +
Sbjct: 175 ESDLHQVIKANDD--LTPEHHQFFLYQLLRGLKYVHAANVFHRDLKPKNILANADCK--- 229
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSP----YTTYVSTRWYRSPEILLRKGYYSK- 263
+K+ D+GLAR N +P +T YV+TRWYR+PE+ ++SK
Sbjct: 230 --------------LKICDFGLARVSFNDAPTAIFWTDYVATRWYRAPELC--GSFFSKY 273
Query: 264 --PLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK------EHFGG 315
+DIW+ GC+ E+ PLFPG + Q+ + D LG+P K + G
Sbjct: 274 TPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPPPEAISKIRNDKARRYLG 333
Query: 316 SWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICAL 375
+ +P+ + +FP + +R ++ + ++P +R +A E A
Sbjct: 334 NMRKKQPV--PFSKKFPKADPSALR-------------LLERLIAFDPKDRPSAEEALAD 378
Query: 376 PYF 378
PYF
Sbjct: 379 PYF 381
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 92.8 bits (229), Expect = 2e-18
Identities = 68/291 (23%), Positives = 131/291 (44%), Gaps = 28/291 (9%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VAIK + R +++ HKN++++ +F + +++VME M
Sbjct: 90 VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELM 149
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q+++ + +L+Q+L G P NI++
Sbjct: 150 DANLCQVIQME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 198
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +DIW
Sbjct: 199 ----------SDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY-KENVDIW 247
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ E+ LFPG D DQ ++++ LG+P K + ++++++P Y L
Sbjct: 248 SVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGL 307
Query: 328 NYEFPYVEGKTIRDVLPNP-QLEDLYDVVTSCLKWNPSERATANEICALPY 377
+ + + D N + D+++ L +P++R + ++ PY
Sbjct: 308 TFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPY 358
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 92.8 bits (229), Expect = 2e-18
Identities = 68/291 (23%), Positives = 131/291 (44%), Gaps = 28/291 (9%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VAIK + R +++ HKN++++ +F + +++VME M
Sbjct: 90 VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELM 149
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q+++ + +L+Q+L G P NI++
Sbjct: 150 DANLCQVIQME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 198
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +DIW
Sbjct: 199 ----------SDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY-KENVDIW 247
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ E+ LFPG D DQ ++++ LG+P K + ++++++P Y L
Sbjct: 248 SVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGL 307
Query: 328 NYEFPYVEGKTIRDVLPNP-QLEDLYDVVTSCLKWNPSERATANEICALPY 377
+ + + D N + D+++ L +P++R + ++ PY
Sbjct: 308 TFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPY 358
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 92.8 bits (229), Expect = 2e-18
Identities = 68/291 (23%), Positives = 131/291 (44%), Gaps = 28/291 (9%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VAIK + R +++ HKN++++ +F + +++VME M
Sbjct: 52 VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELM 111
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q+++ + +L+Q+L G P NI++
Sbjct: 112 DANLCQVIQME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 160
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +DIW
Sbjct: 161 ----------SDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY-KENVDIW 209
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ E+ LFPG D DQ ++++ LG+P K + ++++++P Y L
Sbjct: 210 SVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGL 269
Query: 328 NYEFPYVEGKTIRDVLPNP-QLEDLYDVVTSCLKWNPSERATANEICALPY 377
+ + + D N + D+++ L +P++R + ++ PY
Sbjct: 270 TFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPY 320
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 92.8 bits (229), Expect = 2e-18
Identities = 64/265 (24%), Positives = 120/265 (45%), Gaps = 35/265 (13%)
Query: 123 HKNLVTIYEMFID----DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTL--RSILFQI 176
H N+V++ F D LY L++V+E + + +++++KH + +P + + +QI
Sbjct: 123 HPNVVSLKHCFFSTTEKDELY-LNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQI 181
Query: 177 LAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVN 235
P+N+L++P + VKL D+G A+ +
Sbjct: 182 FRSLSYIHRCIGVCHRDIKPQNLLVNPH----------------THQVKLCDFGSAKVLV 225
Query: 236 NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWR 295
P +Y+ +R+YR+PE++ Y+ +D+W+ GCV+ EL PLFPG DQ+
Sbjct: 226 KGEPNISYICSRYYRAPELIFGATEYTTAIDVWSAGCVLAELLLGQPLFPGESGVDQLVE 285
Query: 296 ILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVV 355
I+ +LG+P P Y ++FP ++ + + D+V
Sbjct: 286 IIKVLGTPTRE---------EIKCMNPNY--TEFKFPQIKAHPWHKIFHKRMPPEAVDLV 334
Query: 356 TSCLKWNPSERATANEICALPYFKE 380
+ L+++P+ R A + P+F E
Sbjct: 335 SRLLQYSPNLRCAALDSLVHPFFDE 359
>YJL141c [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 807
Score = 92.4 bits (228), Expect = 2e-18
Identities = 67/218 (30%), Positives = 110/218 (49%), Gaps = 24/218 (11%)
Query: 90 KGIVAIKTMMNRLPTL-HDYTRVREIKFILQI--PAHKN-LVTIYEMFIDDSLYHLHIVM 145
K I+A+K + +R L T + ++ + Q P +K+ + +Y+ F+ + HL +V
Sbjct: 392 KEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKN--HLCLVF 449
Query: 146 ECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHR 205
E + N+Y+L+K K S+ +R+ QIL PENIL+
Sbjct: 450 ELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAP-- 507
Query: 206 YFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPL 265
D +K+ D+G + R+ YT Y+ +R+YR+PEI+L Y S +
Sbjct: 508 -------------DKPELKIIDFGSSCE-EARTVYT-YIQSRFYRAPEIILGIPY-STSI 551
Query: 266 DIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
D+W+ GC+V EL P+FPG+ E +Q+ RI+D LG P
Sbjct: 552 DMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYP 589
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 92.4 bits (228), Expect = 2e-18
Identities = 74/294 (25%), Positives = 133/294 (45%), Gaps = 34/294 (11%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VAIK + R +++ HKN++ + +F + ++IVME M
Sbjct: 52 VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELM 111
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q+++ + +L+Q+L G P NI++
Sbjct: 112 DANLCQVIQME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 160
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +DIW
Sbjct: 161 ----------SDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY-KENVDIW 209
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ E+ LFPG+D DQ ++++ LG+P K + ++++++P Y
Sbjct: 210 SVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGY 269
Query: 328 NYE--FPYV--EGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
++E FP V + + L Q DL ++ L + S+R + +E PY
Sbjct: 270 SFEKLFPDVLFPADSEHNKLKASQARDL---LSKMLVIDASKRISVDEALQHPY 320
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 92.4 bits (228), Expect = 2e-18
Identities = 74/294 (25%), Positives = 133/294 (45%), Gaps = 34/294 (11%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VAIK + R +++ HKN++ + +F + ++IVME M
Sbjct: 52 VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELM 111
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q+++ + +L+Q+L G P NI++
Sbjct: 112 DANLCQVIQME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 160
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +DIW
Sbjct: 161 ----------SDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY-KENVDIW 209
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ E+ LFPG+D DQ ++++ LG+P K + ++++++P Y
Sbjct: 210 SVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGY 269
Query: 328 NYE--FPYV--EGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
++E FP V + + L Q DL ++ L + S+R + +E PY
Sbjct: 270 SFEKLFPDVLFPADSEHNKLKASQARDL---LSKMLVIDASKRISVDEALQHPY 320
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/254 (26%), Positives = 119/254 (46%), Gaps = 48/254 (18%)
Query: 82 QENWYYKKKGIV--AIKTMMNRLPTLHDYTRV-----------REIKFILQIPAHKNLVT 128
QEN G+V AI + +N+ + TRV REI+ ++ +H+N++
Sbjct: 47 QENLGAGAFGVVCRAIDSKLNKQVAIKKITRVFKNQSTAKCALREIRITREL-SHENIIN 105
Query: 129 IYEMFIDDSL--YHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXX 186
++ + +S ++IVM+ ME ++ ++K + + + +QIL G
Sbjct: 106 STDVLMRESGSGQDIYIVMDLMETDLLSVLK--SNQTLNEKHFQYFFYQILKGLKYLHSA 163
Query: 187 XXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARH------VNNRSP- 239
P N+L++ ++ +K+AD+G++R N SP
Sbjct: 164 GIIHRDLKPANLLLN-----------------EDCSLKIADFGMSRSGPSTKTTPNTSPN 206
Query: 240 ------YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQI 293
+ YVST WYR+PEILL G Y +DIW+ GC++ E+ P+F G+D QI
Sbjct: 207 AHISGDLSQYVSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEMLLLRPIFTGTDSYSQI 266
Query: 294 WRILDLLGSPDHSI 307
+++ LG+PD +
Sbjct: 267 QLLIEYLGTPDEQV 280
>SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase
Length = 591
Score = 92.0 bits (227), Expect = 3e-18
Identities = 117/502 (23%), Positives = 204/502 (40%), Gaps = 114/502 (22%)
Query: 33 YNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKGI 92
Y+++++LG+G+FG V ++ D A + M+ E K+G
Sbjct: 36 YHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTE-------------------KEGF 76
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFI--DDSLYH----LHIVME 146
T +REIK + I H+N++ + +M + D + +++V
Sbjct: 77 --------------PITAIREIKILKSIK-HENIIPLSDMTVVRADKKHRRRGSIYMVTP 121
Query: 147 CMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRY 206
M+ ++ L+++ + F+ P ++ + Q+ AG N+LI
Sbjct: 122 YMDHDLSGLLENPSVK-FTEPQIKCYMKQLFAGTKYLHDQLILHRDLKAANLLI------ 174
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVN--------------NRSPYTTYVSTRWYRSP 252
DN+ ++K+AD+GLAR + NR YT V TRWYRSP
Sbjct: 175 --------DNHG---ILKIADFGLARVITEESYANKNPGLPPPNRREYTGCVVTRWYRSP 223
Query: 253 EILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI--NGK 310
E+LL + Y+ +D+W+ GC++ E+ P+ GS + DQ+ +I L GSP + N +
Sbjct: 224 ELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRLCGSPTQATMPNWE 283
Query: 311 EHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATAN 370
+ G + S P + + GK ++ + + L NP ER +A+
Sbjct: 284 KLPGCEGVRSFPSHPRTLETAFFTFGK------------EMTSLCGAILTLNPDERLSAS 331
Query: 371 EICALPYFKEYVMREASLAKTNNGTASKNKDNTALANKLAANPSISNQWS------RILS 424
YF A+ ++ + +AS D + AN Q + R ++
Sbjct: 332 MALEHEYFTT-PPYPANPSELQSYSASHEYDKRRKREQRDANSHAFEQTANGKRQFRFMT 390
Query: 425 GLPHNPELGI-VPSFNSPQKLPKVQKNNQMNCVTDKSQQQPRRGGVASWFKFSTQKNHVN 483
P +P GI P++NS P+ Q+ + R GG + +VN
Sbjct: 391 RGPSDPWYGIRRPNYNSQ---PQYQRGS-----------YNREGGNMD------RSRNVN 430
Query: 484 INPNTNNDEKILTSVNTNTNSQ 505
P + K LTS NS+
Sbjct: 431 YQPKRQQNFKPLTSDLPQKNSE 452
>At1g53510 [T] KOG0660 Mitogen-activated protein kinase
Length = 603
Score = 92.0 bits (227), Expect = 3e-18
Identities = 92/361 (25%), Positives = 153/361 (41%), Gaps = 80/361 (22%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY +++ +GKGS+G V A +
Sbjct: 12 RYRILEVIGKGSYGVVCAAIDTHTGEK--------------------------------- 38
Query: 92 IVAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFIDDS---LYHLHIVMEC 147
VAIK + + + D R+ RE+K +L++ H ++V I + + S +++V E
Sbjct: 39 -VAIKKINDVFEHISDALRILREVK-LLRLLRHPDIVEIKSIMLPPSKREFKDIYVVFEL 96
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
ME +++Q++K + + L+Q+L P+NIL +
Sbjct: 97 MESDLHQVIKANDD--LTREHHQFFLYQMLRALKFMHTANVYHRDLKPKNILANA----- 149
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSP----YTTYVSTRWYRSPEILLRKGYYSK 263
N +K+ D+GLAR N +P +T YV+TRWYR+PE+ ++SK
Sbjct: 150 ------------NCKLKVCDFGLARVAFNDTPTTVFWTDYVATRWYRAPELC--GSFFSK 195
Query: 264 ---PLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP-DHSING-KEHFGGSWL 318
+D+W+ GC+ E+ T PLFPG Q+ I DLLG+P +I+G + +L
Sbjct: 196 YTPAIDVWSIGCIFAEVLTGKPLFPGKSVVHQLELITDLLGTPKSETISGVRNDKARKYL 255
Query: 319 DSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
+ + + + D L L+ L L ++P +R T E A PYF
Sbjct: 256 TEMRKKNPVTFSQKFSKA----DPLALRLLQRL-------LAFDPKDRPTPAEALADPYF 304
Query: 379 K 379
K
Sbjct: 305 K 305
>Hs11386209 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 1215
Score = 91.7 bits (226), Expect = 4e-18
Identities = 68/227 (29%), Positives = 105/227 (45%), Gaps = 23/227 (10%)
Query: 85 WYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHK----NLVTIYEMFIDDSLYH 140
W IVAIK + N P+ ++ E+ + ++ N V YE F + H
Sbjct: 215 WKRGTNEIVAIKILKNH-PSYARQGQI-EVSILARLSTENADEYNFVRAYECFQHRN--H 270
Query: 141 LHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILI 200
+V E +EQN+Y +K K L +R IL Q+ PENI++
Sbjct: 271 TCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIML 330
Query: 201 SPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGY 260
D Y VK+ D+G A HV+ ++ +TY+ +R+YR+PEI+L +
Sbjct: 331 V-------------DPVRQPYRVKVIDFGSASHVS-KTVCSTYLQSRYYRAPEIILGLPF 376
Query: 261 YSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSI 307
+ +D+W+ GCV+ EL PL+PG+ E DQI I G P +
Sbjct: 377 -CEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQL 422
>CE06352 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 948
Score = 91.7 bits (226), Expect = 4e-18
Identities = 131/614 (21%), Positives = 243/614 (39%), Gaps = 122/614 (19%)
Query: 26 LKN---IDARYNVIQE--LGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNV 80
LKN D RY ++ + +GKGSFG VT A Y ++ I+ +
Sbjct: 382 LKNGEIFDKRYVILSDTPVGKGSFGQVTKA----------------YDTLNKEEVAIKII 425
Query: 81 EQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYH 140
+ + ++ + I+ + L HD ++ K+ N+VT+ F+ + H
Sbjct: 426 KNKKTFFDQ---AQIEIHLLELTNAHD----KDNKY--------NIVTLKGHFVHRA--H 468
Query: 141 LHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXX--XXPENI 198
L +V E + N+Y L+K+ R SL R Q+ PEN+
Sbjct: 469 LCLVFELLSYNLYDLLKNTSFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENV 528
Query: 199 LISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRK 258
L+ + R +++ D+G + +R Y+ +R+YRSPE+LL
Sbjct: 529 LLVNAKRS---------------QIRVIDFGSSCQTGHR--IYQYIQSRFYRSPEVLLGI 571
Query: 259 GYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDH---SINGKEHFGG 315
Y +K +D+W+ GC++VE+ T PLF GS E DQ+ +I+++LG P I K H
Sbjct: 572 AYDTK-IDMWSLGCILVEMHTGEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTH--- 627
Query: 316 SWLDS--------KPLYQALNYEFPYVEGKTIRDVL--------------PNPQLED--- 350
+ D K + + + + ++L P +ED
Sbjct: 628 KYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSVEDYSK 687
Query: 351 LYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNGTASKN-----KDNTAL 405
D++ L+++P +R + + P+ K+ R S ++ + + ++
Sbjct: 688 FKDLIKRMLQFDPKQRISPYYVVRHPFLKQKEERVPSQPPVSHSNLQQQQQLYIQQPSSQ 747
Query: 406 ANKLAANPSI------SNQWSRILSGLPHNPELGIVPSFNSPQKLPKVQKNNQMNCVTDK 459
+++ +PS+ N R G NP + + SF+ + +V + +
Sbjct: 748 MSQVMESPSVGSVYVEDNGMYRQAPGSSANP-ISVTSSFDEGDAM-EVDAGRRRFSAHQQ 805
Query: 460 SQQQPRRGGVASWFKFS-TQKNHVNINPNTNNDEKILTSVNTNTNSQKNQGIVEKKQQEQ 518
+ P +++S Q+ T + Q Q ++++QQ+Q
Sbjct: 806 NYHNPN-------YQYSQPQQQQQQQYQQTQRTQLEQQQKQAQLQQQLQQQQMQQQQQQQ 858
Query: 519 QVNAHNERLDSSTNANGNSIPDINLIGHANNDNEVFT-IELDDSMETMTGSDQISKELND 577
Q H + SS+ + S + NE ELDD+ + Q ++++D
Sbjct: 859 QQRQHMPQAQSSSQQHLQS----RARPRQQDQNEWRNQFELDDTFQ------QKQRKVDD 908
Query: 578 KIELYQDTTNQMNP 591
+ Q + NQ NP
Sbjct: 909 SVS-NQISRNQFNP 921
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 91.3 bits (225), Expect = 5e-18
Identities = 63/195 (32%), Positives = 96/195 (48%), Gaps = 22/195 (11%)
Query: 112 REIKFILQIPAHKNLVTIYE-MFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLR 170
REI IL+ H N++ + M +D L+++ E ME ++ L FS P ++
Sbjct: 149 REI-IILRKLDHPNVIKLEGLMLVDHDSSTLYLIFEYMEHDLLGLSSLLGVH-FSEPQVK 206
Query: 171 SILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGL 230
+ Q+L G N+LI+ + V+K+AD+GL
Sbjct: 207 CYMRQLLRGLDHCHTNHVLHRDMKSSNLLIN-----------------GDGVLKIADFGL 249
Query: 231 ARHVN--NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSD 288
A + N P TT+V+T WYR PE+LL +Y +D+W+ GCV+ EL P+ PG +
Sbjct: 250 ATFFDPHNSVPLTTHVATLWYRPPELLLGASHYGIGVDLWSTGCVIGELYAGKPILPGKN 309
Query: 289 ETDQIWRILDLLGSP 303
ETDQ+ +I L GSP
Sbjct: 310 ETDQLHKIFKLCGSP 324
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 91.3 bits (225), Expect = 5e-18
Identities = 66/278 (23%), Positives = 127/278 (44%), Gaps = 34/278 (12%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEM---FIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFS 165
T +REI + + ++V + ++ + L++V E ++ ++ + ++ ++ +
Sbjct: 59 TTLREISILRMLARDPHIVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFIRSFRQAGQN 118
Query: 166 LP--TLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVV 223
+P T++ +++Q+ G P N+L+ +
Sbjct: 119 IPQNTVKCLMYQLCKGMAFCHGHGVLHRDLKPHNLLMDRK----------------TMTL 162
Query: 224 KLADYGLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSP 282
K+AD GLAR YT + T WYR+PE+LL +YS +D+W+ GC+ EL T
Sbjct: 163 KIADLGLARAFTLPMKKYTHEILTLWYRAPEVLLGATHYSTGVDMWSVGCIFAELVTKQA 222
Query: 283 LFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDV 342
+F G E Q+ RI LLG+P+ + W L +E+P + ++
Sbjct: 223 IFAGDSELQQLLRIFRLLGTPNEEV---------WPGVSKLKDW--HEYPQWKPLSLSTA 271
Query: 343 LPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+PN L D+++ L++ P++R +A + PYF +
Sbjct: 272 VPNLDEAGL-DLLSKMLEYEPAKRISAKKAMEHPYFDD 308
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 91.3 bits (225), Expect = 5e-18
Identities = 80/339 (23%), Positives = 141/339 (40%), Gaps = 52/339 (15%)
Query: 112 REIKFILQIPAHKNLVTIYEMFI---DDSLYHLHIVMECMEQNIYQLMKH--RKRRVFSL 166
RE++ I+Q+ H N V + F D+ +L++V+E + + + ++ + R ++ L
Sbjct: 123 RELQ-IMQMLDHPNAVALKHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPL 181
Query: 167 PTLRSILFQILAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
++ +QI P+N+L++P + +K+
Sbjct: 182 IYVKLYTYQICRALAYIHNSFGLCHRDIKPQNLLVNPH----------------THQLKI 225
Query: 226 ADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFP 285
D+G A+ + P +Y+ +R+YR+PE++ Y+ +DIW+ GCV+ EL PLFP
Sbjct: 226 CDFGSAKVLVKGEPNVSYICSRYYRAPELIFGASEYTTAIDIWSTGCVMAELLLGQPLFP 285
Query: 286 GSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPN 345
G DQ+ I+ +LG+P P Y ++FP ++ V
Sbjct: 286 GESGVDQLVEIIKVLGTPTRE---------EIKCMNPNY--TEFKFPQIKPHPWHKVFQK 334
Query: 346 PQLEDLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTNNGTASKNKDNTAL 405
+ D++ +++P+ R TA E C P F E NT L
Sbjct: 335 RLPPEAVDLLCRFFQYSPNLRCTALEACIHPLFDEL-----------------RDPNTRL 377
Query: 406 ANKLAANPSISNQWSRILSGLPHNPELGIVPSFNSPQKL 444
N P + N + LSG+P +VP Q L
Sbjct: 378 PNGRPL-PPLFNFKPQELSGIPPEIVNRLVPEHARKQNL 415
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 90.9 bits (224), Expect = 7e-18
Identities = 92/387 (23%), Positives = 159/387 (40%), Gaps = 80/387 (20%)
Query: 6 LTTADSFIPPDVNNPPFYIPLKNIDARYNVIQE---LGKGSFGSVTLAETMYDMNSSATQ 62
L FI DV + K+ + R +++E +G+G+FG+V A D
Sbjct: 11 LQRGSEFIADDVTSN------KSNNTRRMLVKEYRKIGRGAFGTVVQAYLTQD------- 57
Query: 63 ISSMYPETLMDQTLIRNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPA 122
++NW G AIK ++P +Y + RE++ IL+I
Sbjct: 58 -------------------KKNWL----GPFAIK----KVPAHTEY-KSRELQ-ILRIAD 88
Query: 123 HKNLVTIYEMFI----DDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT--LRSILFQI 176
H N+V + F D+ + H+ MEC+ + + + +P +R +QI
Sbjct: 89 HPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQI 148
Query: 177 LAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNN 236
G P N+L+ P + V+K+ D+G A+ + +
Sbjct: 149 ARGMLYLHGLGVCHRDIKPSNVLVDP----------------ETGVLKICDFGSAKKLEH 192
Query: 237 RSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRI 296
P +Y+ +R+YR+PE+++ Y+ +DIW GCV+ E+ +F G + Q+ I
Sbjct: 193 NQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREI 252
Query: 297 LDLLGSPDHS--INGKEHFGGSWLDSKPLYQALNYE-FPYVEGKTIRDVLPNPQLEDLYD 353
LLG PD + G L SKPL+ + + F G + D + D
Sbjct: 253 AKLLGPPDKRFIFFSNPAYDGP-LFSKPLFSGSSQQRFEKYFGHSGPDGI---------D 302
Query: 354 VVTSCLKWNPSERATANEICALPYFKE 380
++ L + P +R + I A +F E
Sbjct: 303 LLMKILVYEPQQRLSPRRILAHQFFNE 329
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 90.9 bits (224), Expect = 7e-18
Identities = 73/294 (24%), Positives = 132/294 (44%), Gaps = 34/294 (11%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VAIK + R +++ HKN++ + +F + ++IVME M
Sbjct: 52 VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELM 111
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q+++ + +L+Q+L G P NI++
Sbjct: 112 DANLCQVIQME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 160
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +D+W
Sbjct: 161 ----------SDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY-KENVDLW 209
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ E+ LFPG D DQ ++++ LG+P K + ++++++P Y
Sbjct: 210 SVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGY 269
Query: 328 NYE--FPYV--EGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
++E FP V + + L Q DL ++ L + S+R + +E PY
Sbjct: 270 SFEKLFPDVLFPADSEHNKLKASQARDL---LSKMLVIDASKRISVDEALQHPY 320
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 90.9 bits (224), Expect = 7e-18
Identities = 79/291 (27%), Positives = 133/291 (45%), Gaps = 54/291 (18%)
Query: 111 VREIKFILQIPAHKNLVTIYEMF-------IDD-----SLYHLHIVMECMEQNIYQLMKH 158
+REIK I ++ H N+V ++E+ DD L ++IV E ME ++ +++
Sbjct: 63 LREIKIIRRLD-HDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQ 121
Query: 159 RKRRVFSLPTL----RSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLED 214
P L R ++Q+L G P N+ I+
Sbjct: 122 G-------PLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFIN------------- 161
Query: 215 DNYSDNYVVKLADYGLAR----HVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAY 270
+++ V+K+ D+GLAR H +++ + + T+WYRSP +LL Y+K +D+WA
Sbjct: 162 ---TEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAA 218
Query: 271 GCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYE 330
GC+ E+ T LF G+ E +Q+ IL+ + H + +E L P+Y +
Sbjct: 219 GCIFAEMLTGKTLFAGAHELEQMQLILESI-PVVHEEDRQE-----LLSVIPVYIRNDMT 272
Query: 331 FPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKEY 381
P+ K + +LP E L D + L ++P +R TA E + PY Y
Sbjct: 273 EPH---KPLTQLLPGISREAL-DFLEQILTFSPMDRLTAEEALSHPYMSIY 319
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 90.9 bits (224), Expect = 7e-18
Identities = 73/294 (24%), Positives = 132/294 (44%), Gaps = 34/294 (11%)
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFID----DSLYHLHIVMECM 148
VAIK + R +++ HKN++ + +F + ++IVME M
Sbjct: 52 VAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELM 111
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ N+ Q+++ + +L+Q+L G P NI++
Sbjct: 112 DANLCQVIQME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK------- 160
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+ +K+ D+GLAR T YV TR+YR+PE++L GY + +D+W
Sbjct: 161 ----------SDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY-KENVDLW 209
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPLYQAL 327
+ GC++ E+ LFPG D DQ ++++ LG+P K + ++++++P Y
Sbjct: 210 SVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGY 269
Query: 328 NYE--FPYV--EGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPY 377
++E FP V + + L Q DL ++ L + S+R + +E PY
Sbjct: 270 SFEKLFPDVLFPADSEHNKLKASQARDL---LSKMLVIDASKRISVDEALQHPY 320
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 90.5 bits (223), Expect = 9e-18
Identities = 69/245 (28%), Positives = 119/245 (48%), Gaps = 24/245 (9%)
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
IVA+K + T +REI + ++ H N++++ ++ ++ L +V E ME++
Sbjct: 28 IVALKVIRIDADEGTPSTAIREISLMKEL-RHPNIMSLSDVLQTEN--KLMLVFEYMEKD 84
Query: 152 IYQLMKHRKRRVFSLPT-LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKK 210
+ + M + P+ +++ Q+L G P+N+LI+
Sbjct: 85 LKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGE----- 139
Query: 211 WLEDDNYSDNYVVKLADYGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWA 269
+KLAD+GLAR + + ++ V T WYR+P++LL YS +DIW+
Sbjct: 140 ------------LKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRVYSTSIDIWS 187
Query: 270 YGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQA--L 327
GC++ E+AT PLF GS+ DQ+ +I LLG+P + + P+Y+A L
Sbjct: 188 VGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYKPTFPIYKAQDL 247
Query: 328 NYEFP 332
Y FP
Sbjct: 248 AYLFP 252
>At1g53050 [D] KOG0600 Cdc2-related protein kinase
Length = 694
Score = 90.5 bits (223), Expect = 9e-18
Identities = 81/296 (27%), Positives = 128/296 (42%), Gaps = 39/296 (13%)
Query: 89 KKGIVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMEC 147
+K IVA+K + + L REI+ + ++ H N++ + + L++V E
Sbjct: 156 QKKIVALKKVRFDNLEPESVRFMAREIQILRRLD-HPNIIKLEGLVTSRMSCSLYLVFEY 214
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
ME ++ L H + FS ++ L Q+L G N+LI S
Sbjct: 215 MEHDLAGLASHPAIK-FSESQVKCYLQQLLHGLDHCHSRGVLHRDIKGSNLLIDNSG--- 270
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRS--PYTTYVSTRWYRSPEILLRKGYYSKPL 265
V+K+AD+GLA + R P T+ V T WYR PE+LL Y +
Sbjct: 271 --------------VLKIADFGLASFFDPRQTQPLTSRVVTLWYRPPELLLGATRYGAAV 316
Query: 266 DIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSK-PLY 324
D+W+ GC++ EL P+ PG E +Q+ +I L GSP W+ S+ P
Sbjct: 317 DLWSAGCILAELYAGKPIMPGRTEVEQLHKIFKLCGSPTEDY---------WVKSRLPHA 367
Query: 325 QALNYEFPY--VEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
PY + G+T ++ P P L ++ + L NP +R TA +F
Sbjct: 368 TIFKPTQPYKRLVGETFKE-FPQPALA----LLETLLSVNPDDRGTATAALKSEFF 418
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 90.5 bits (223), Expect = 9e-18
Identities = 89/345 (25%), Positives = 147/345 (41%), Gaps = 66/345 (19%)
Query: 31 ARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKK 90
+RY +++++G+G G V A D+ + + I+ V +N K
Sbjct: 7 SRYKMLEKIGEGVHGCVFKA---IDLQRNK-------------EVAIKKVALKN----KF 46
Query: 91 GIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQ 150
G +A+ T+ REIK LQ+ + ++ I +++ D L L +V+E
Sbjct: 47 GNIALNTL-------------REIK-TLQLCKSEYILDIIDIYPD--LTGLSLVLEYQPD 90
Query: 151 NIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKK 210
+Y +K + S +R Q+ G P N+LIS
Sbjct: 91 TLYNRLKSEVNPL-SRQQVRKFAHQMFKGIAYLHEAGLMHRDIKPANLLIS--------- 140
Query: 211 WLEDDNYSDNYVVKLADYGLARHV---NNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
D ++K+AD+GLAR + Y+ VSTRWYR+PEIL Y +D+
Sbjct: 141 --------DTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGSQKYGTGVDM 192
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQAL 327
WA GCVV E+ PLF G+ + +Q+ I+ LGSP + W + L
Sbjct: 193 WAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGSPRLN---------QWPELTSLPDYS 243
Query: 328 NYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEI 372
FP G ++ P+ ++V++ + +NP R A+E+
Sbjct: 244 KIRFPNSVGIHWDNLFPSCTHAVEINLVSNLVVYNPKNRLKASEV 288
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 90.1 bits (222), Expect = 1e-17
Identities = 75/275 (27%), Positives = 117/275 (42%), Gaps = 47/275 (17%)
Query: 117 ILQIPAHKNLVTIYEMFIDDS--------LYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
ILQ H NLVT+ E F + LY + VME + Q + + +PT
Sbjct: 89 ILQNIRHPNLVTL-EFFFESHCTTKDGGHLYQKNFVMEYIPQTLSSEIHEYFDNGSKMPT 147
Query: 169 --LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLA 226
++ FQIL P NILI PS + + K+
Sbjct: 148 KHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPS----------------SGIAKVC 191
Query: 227 DYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPG 286
D+G A+ +++ + TY +R+YR+PE+LL Y+ +DIW+ GC++ E+ PLF G
Sbjct: 192 DFGSAQRLDDNTELKTYFCSRFYRAPELLLNSKDYTTQIDIWSLGCIIGEMIKGQPLFKG 251
Query: 287 SDETDQIWRILDLLGS-PDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPN 345
Q+ I LLG P SI + S D K ++ + FP +E
Sbjct: 252 DSANSQLEEIAKLLGRFPKSSIKNSQELQDSLNDQK--FKKFMHWFPSIE---------- 299
Query: 346 PQLEDLYDV--VTSCLKWNPSERATANEICALPYF 378
+DV + L ++ +ER A ++ A +F
Sbjct: 300 -----FFDVEFLLKVLTYDATERCDARQLMAHEFF 329
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 90.1 bits (222), Expect = 1e-17
Identities = 66/275 (24%), Positives = 125/275 (45%), Gaps = 34/275 (12%)
Query: 112 REIKFILQIPAHKNLVTIYEMFI---DDSLYHLHIVMECMEQNIYQLMKH--RKRRVFSL 166
RE++ I+Q+ H N+V + F ++ +L++V+E + + + + + R ++ L
Sbjct: 122 RELQ-IMQMLDHPNVVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPL 180
Query: 167 PTLRSILFQILAGXXXXXXXXXX-XXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
++ +QI G P+N+L++P + +K+
Sbjct: 181 IYVKLYTYQICRGLAYLHNCCGLCHRDIKPQNLLVNPH----------------THQLKI 224
Query: 226 ADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFP 285
D+G A+ + P +Y+ +R+YR+PE++ Y+ +DIW+ GCV+ EL PLFP
Sbjct: 225 CDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFP 284
Query: 286 GSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPN 345
G DQ+ I+ +LG+P P Y ++FP ++ V
Sbjct: 285 GESGVDQLVEIIKVLGTPTRE---------EIKCMNPNY--TEFKFPQIKPHPWHKVFQK 333
Query: 346 PQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ D++ +++P+ R TA E C P+F E
Sbjct: 334 RLPPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDE 368
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 89.7 bits (221), Expect = 1e-17
Identities = 70/264 (26%), Positives = 118/264 (44%), Gaps = 36/264 (13%)
Query: 111 VREIKFILQIPA--HKNLVTIYEMFID---DSLYHLHIVMECMEQNIYQLMKHRKRRVFS 165
VRE+ + ++ A H N+V + ++ D + +V E ++Q++ +
Sbjct: 54 VREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLP 113
Query: 166 LPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
T++ ++ Q L G PENIL++ VKL
Sbjct: 114 AETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGG-----------------TVKL 156
Query: 226 ADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFP 285
AD+GLAR + + T V T WYR+PE+LL+ Y + P+D+W+ GC+ E+ PLF
Sbjct: 157 ADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTY-ATPVDMWSVGCIFAEMFRRKPLFC 215
Query: 286 GSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPN 345
G+ E DQ+ +I DL+G P W L + FP + ++ V+P
Sbjct: 216 GNSEADQLGKIFDLIGLPPED---------DWPRDVSLPRG---AFPPRGPRPVQSVVPE 263
Query: 346 PQLEDLYDVVTSCLKWNPSERATA 369
+ E ++ L +NP +R +A
Sbjct: 264 ME-ESGAQLLLEMLTFNPHKRISA 286
>At4g24740 [T] KOG0671 LAMMER dual specificity kinases
Length = 427
Score = 89.7 bits (221), Expect = 1e-17
Identities = 93/380 (24%), Positives = 155/380 (40%), Gaps = 78/380 (20%)
Query: 28 NIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYY 87
++ RY + ++G+G+FG V E W
Sbjct: 93 DLTPRYKIYSKMGEGTFGQVL----------------------------------ECWDR 118
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAH----KNLVTIYEMFIDDSLYHLHI 143
++K +VA+K + R + + EI+ + Q+ H V I F D H+ I
Sbjct: 119 ERKEMVAVKIV--RGVKKYREAAMIEIEMLQQLGKHDKGGNRCVQIRNWF--DYRNHICI 174
Query: 144 VMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPS 203
V E + ++Y ++ R F + +R I +Q+L PENIL+ S
Sbjct: 175 VFEKLGSSLYDFLRKNNYRSFPIDLVREIGWQLLECVAFMHDLRMIHTDLKPENILLVSS 234
Query: 204 H-----RYFSKKWLEDDNYS---DNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEIL 255
Y + D Y + +K+ D+G + R T VSTR YR+PE++
Sbjct: 235 DYVKIPEYKGSRLQRDVCYKRVPKSSAIKVIDFGSTTY--ERQDQTYIVSTRHYRAPEVI 292
Query: 256 LRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS-PDHSINGKEHFG 314
L G+ S P D+W+ GC++VEL T LF + + + + +LG P + +
Sbjct: 293 LGLGW-SYPCDVWSVGCIIVELCTGEALFQTHENLEHLAMMERVLGPFPQQMLKKVDRHS 351
Query: 315 GSWLDSKPLYQALNYEFPYVEGKTIRD----VLPNPQLE------------DLYDVVTSC 358
++ L + +G T RD VL P+L+ +L ++V
Sbjct: 352 EKYVRRGRL--------DWPDGATSRDSLKAVLKLPRLQNLIMQHVDHSAGELINMVQGL 403
Query: 359 LKWNPSERATANEICALPYF 378
L+++PSER TA E P+F
Sbjct: 404 LRFDPSERITAREALRHPFF 423
>Hs4758008 [T] KOG0671 LAMMER dual specificity kinases
Length = 484
Score = 89.4 bits (220), Expect = 2e-17
Identities = 87/360 (24%), Positives = 154/360 (42%), Gaps = 49/360 (13%)
Query: 29 IDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYK 88
+ ARY ++ LG+G+FG V D + ++ +++NV++ Y
Sbjct: 157 LSARYEIVDTLGEGAFGKVV---ECIDHKAGGRHVAVK---------IVKNVDR----YC 200
Query: 89 KKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECM 148
+ I+ ++ L T + R ++ + H H+ IV E +
Sbjct: 201 EAARSEIQ-VLEHLNTTDPNSTFRCVQMLEWFEHHG---------------HICIVFELL 244
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH--RY 206
+ Y +K F L +R + +QI PENIL S
Sbjct: 245 GLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEA 304
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
++ K D+ N +K+ D+G A + + ++T VSTR YR+PE++L G+ S+P D
Sbjct: 305 YNPKIKRDERTLINPDIKVVDFGSATYDDEH--HSTLVSTRHYRAPEVILALGW-SQPCD 361
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS-PDHSI---NGKEHFGGSWLDSKP 322
+W+ GC+++E +FP D + + + +LG P H I +++F LD
Sbjct: 362 VWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDE 421
Query: 323 LYQALNYEF----PYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
A Y P E +DV + E L+D++ L+++P++R T E P+F
Sbjct: 422 HSSAGRYVSRACKPLKEFMLSQDV----EHERLFDLIQKMLEYDPAKRITLREALKHPFF 477
>Hs22045050 [T] KOG0671 LAMMER dual specificity kinases
Length = 484
Score = 89.4 bits (220), Expect = 2e-17
Identities = 87/360 (24%), Positives = 154/360 (42%), Gaps = 49/360 (13%)
Query: 29 IDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYK 88
+ ARY ++ LG+G+FG V D + ++ +++NV++ Y
Sbjct: 157 LSARYEIVDTLGEGAFGKVV---ECIDHKAGGRHVAVK---------IVKNVDR----YC 200
Query: 89 KKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECM 148
+ I+ ++ L T + R ++ + H H+ IV E +
Sbjct: 201 EAARSEIQ-VLEHLNTTDPNSTFRCVQMLEWFEHHG---------------HICIVFELL 244
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH--RY 206
+ Y +K F L +R + +QI PENIL S
Sbjct: 245 GLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEA 304
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
++ K D+ N +K+ D+G A + + ++T VSTR YR+PE++L G+ S+P D
Sbjct: 305 YNPKIKRDERTLINPDIKVVDFGSATYDDEH--HSTLVSTRHYRAPEVILALGW-SQPCD 361
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS-PDHSI---NGKEHFGGSWLDSKP 322
+W+ GC+++E +FP D + + + +LG P H I +++F LD
Sbjct: 362 VWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDE 421
Query: 323 LYQALNYEF----PYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
A Y P E +DV + E L+D++ L+++P++R T E P+F
Sbjct: 422 HSSAGRYVSRRCKPLKEFMLSQDV----EHERLFDLIQKMLEYDPAKRITLREALKHPFF 477
>At3g53570 [T] KOG0671 LAMMER dual specificity kinases
Length = 467
Score = 89.0 bits (219), Expect = 2e-17
Identities = 100/407 (24%), Positives = 171/407 (41%), Gaps = 75/407 (18%)
Query: 14 PPDVNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMD 73
P D + ++ + RY ++ ++G+G+FG V E + N I
Sbjct: 96 PDDKDGHYVFVVGDTLTPRYQILSKMGEGTFGQVL--ECFDNKNKEVVAIK--------- 144
Query: 74 QTLIRNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMF 133
+IR++ + Y++ ++ I ++ RL T HD R V I F
Sbjct: 145 --VIRSINK----YREAAMIEID-VLQRL-TRHDVGGSR-------------CVQIRNWF 183
Query: 134 IDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXX 193
D H+ IV E + ++Y ++ R F + +R + Q+L
Sbjct: 184 --DYRNHICIVFEKLGPSLYDFLRKNSYRSFPIDLVRELGRQLLESVAYMHDLRLIHTDL 241
Query: 194 XPENILIS-------PSHRYFSKKWLEDDNYSDNY----VVKLADYGLARHVNNRSPYTT 242
PENIL+ P +++ S+ +D +Y N +KL D+G + Y
Sbjct: 242 KPENILLVSSEYIKIPDYKFLSRP-TKDGSYFKNLPKSSAIKLIDFGSTTFEHQDHNYI- 299
Query: 243 YVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS 302
VSTR YR+PE++L G+ + P D+W+ GC++VEL + LF + + + + +LG
Sbjct: 300 -VSTRHYRAPEVILGVGW-NYPCDLWSIGCILVELCSGEALFQTHENLEHLAMMERVLGP 357
Query: 303 -PDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDV---------LPNPQLE--- 349
P H + + K + ++P EG T RD LPN ++
Sbjct: 358 LPPHMVLRADR-----RSEKYFRRGAKLDWP--EGATSRDSLKAVWKLPRLPNLIMQHVD 410
Query: 350 ----DLYDVVTSCLKWNPSERATANEICALPYFKEYVMREASLAKTN 392
DL D++ L+++P+ER A E P+F RE S+ N
Sbjct: 411 HSAGDLIDLLQGLLRYDPTERFKAREALNHPFFTR--SREQSIPPFN 455
>At1g18670 [D] KOG0600 Cdc2-related protein kinase
Length = 662
Score = 89.0 bits (219), Expect = 2e-17
Identities = 72/271 (26%), Positives = 117/271 (42%), Gaps = 33/271 (12%)
Query: 112 REIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRS 171
REI IL+ H N++ + + +H+V E ME ++ L+ F+ P ++
Sbjct: 177 REI-LILRKLNHPNIIKLEGIVTSKLSCSIHLVFEYMEHDLTGLLSSPDID-FTTPQIKC 234
Query: 172 ILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLA 231
+ Q+L+G N+L++ + ++K+AD+GLA
Sbjct: 235 YMKQLLSGLDHCHARGVMHRDIKGSNLLVN-----------------NEGILKVADFGLA 277
Query: 232 RHVN---NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSD 288
N N+ P T+ V T WYR PE+LL Y +D+W+ GCV EL P+ G
Sbjct: 278 NFCNASGNKQPLTSRVVTLWYRPPELLLGATEYGASVDLWSVGCVFAELLIGKPVLQGRT 337
Query: 289 ETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQL 348
E +Q+ +I L GSP W SK + L + +G +R+ L L
Sbjct: 338 EVEQLHKIFKLCGSPPEDY---------WKKSKLPHAMLFKPQQHYDG-CLRETLKLKGL 387
Query: 349 EDL-YDVVTSCLKWNPSERATANEICALPYF 378
D +++ + L P +R TA+ YF
Sbjct: 388 SDADINLIETLLSIQPHKRGTASTALVSQYF 418
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 89.0 bits (219), Expect = 2e-17
Identities = 77/273 (28%), Positives = 121/273 (44%), Gaps = 36/273 (13%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLR 170
+REI + ++ HKN+V + ++ D L +V E +Q++ + + + R
Sbjct: 49 LREICLLKELK-HKNIVRLIDVLHSDK--KLTLVFEHCDQDLKKYFDSLNGEI-DMAVCR 104
Query: 171 SILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGL 230
S + Q+L G P+N+LI+ N +KLAD+GL
Sbjct: 105 SFMLQLLRGLAFCHSHNVLHRDLKPQNLLINK-----------------NGELKLADFGL 147
Query: 231 ARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFS-PLFPGSD 288
AR Y+ V T WYR P++L Y+ +D+W+ GC++ ELA PLFPGSD
Sbjct: 148 ARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPGSD 207
Query: 289 ETDQIWRILDLLGSP-DHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQ 347
DQ+ +I +LG+P + S G H Y AL FP + + N +
Sbjct: 208 VLDQLMKIFRVLGTPNEDSWPGVSHLSD--------YVALP-SFPAITSWSQLVPRLNSK 258
Query: 348 LEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
DL + C P++R +A PYF +
Sbjct: 259 GRDLLQKLLIC---RPNQRISAEAAMQHPYFTD 288
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 88.6 bits (218), Expect = 3e-17
Identities = 73/257 (28%), Positives = 123/257 (47%), Gaps = 49/257 (19%)
Query: 74 QTLIRNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRV-----REIKFILQIPAHKNLVT 128
QTLI+ + KK KT + + LH YT + RE+ ++ +K+L T
Sbjct: 169 QTLIKKPLTVFYAIKK-----FKTEKDGVEQLH-YTGISQSACREMALCRELH-NKHLTT 221
Query: 129 IYEMFIDDSLYHLHIVMECMEQNIYQLM---KHRKRRVFSLPTLRSILFQILAGXXXXXX 185
+ E+F++ +H+V E E ++ Q++ H ++R+ +RSI++Q+L G
Sbjct: 222 LVEIFLERKC--VHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQ 279
Query: 186 XXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNN--RSPYT-- 241
P NI+++ VK+ D GLAR +N ++ YT
Sbjct: 280 NWVLHRDLKPANIMVTIDG-----------------CVKIGDLGLARKFHNMLQTLYTGD 322
Query: 242 TYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSD-----------ET 290
V T WYR+PE+LL +Y+ +D+W+ GC+ EL P+F G + +
Sbjct: 323 KVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQV 382
Query: 291 DQIWRILDLLGSPDHSI 307
+Q+ RIL++LG+PD I
Sbjct: 383 NQLQRILEVLGTPDQKI 399
>CE23751 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 796
Score = 88.2 bits (217), Expect = 4e-17
Identities = 70/276 (25%), Positives = 120/276 (43%), Gaps = 51/276 (18%)
Query: 28 NIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYY 87
+I RY V++ +GKGSFG V A + ++ V E ++
Sbjct: 456 HIAYRYEVLKVIGKGSFGQVIKA----------------FDHKYQQYVALKLVRNEKRFH 499
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMEC 147
++ + + D+ R ++ N++ + + F + H I E
Sbjct: 500 RQA---------DEEIRILDHLRRQDSD------GTHNIIHMLDYF--NFRNHKCITFEL 542
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
+ N+Y+L+K K + FSL +R + +L PEN+L+ R
Sbjct: 543 LSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSG 602
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
+K+ D+G + + R TY+ +R+YR+PE++L Y P+D+
Sbjct: 603 ---------------IKVIDFGSSCFDDQR--IYTYIQSRFYRAPEVILGTKY-GMPIDM 644
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
W+ GC++ EL T PL PG DE DQ+ I++LLG P
Sbjct: 645 WSLGCILAELLTGYPLLPGEDENDQLALIIELLGMP 680
>CE19878 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 817
Score = 88.2 bits (217), Expect = 4e-17
Identities = 70/276 (25%), Positives = 120/276 (43%), Gaps = 51/276 (18%)
Query: 28 NIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYY 87
+I RY V++ +GKGSFG V A + ++ V E ++
Sbjct: 456 HIAYRYEVLKVIGKGSFGQVIKA----------------FDHKYQQYVALKLVRNEKRFH 499
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMEC 147
++ + + D+ R ++ N++ + + F + H I E
Sbjct: 500 RQA---------DEEIRILDHLRRQDSD------GTHNIIHMLDYF--NFRNHKCITFEL 542
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
+ N+Y+L+K K + FSL +R + +L PEN+L+ R
Sbjct: 543 LSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSG 602
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
+K+ D+G + + R TY+ +R+YR+PE++L Y P+D+
Sbjct: 603 ---------------IKVIDFGSSCFDDQR--IYTYIQSRFYRAPEVILGTKY-GMPIDM 644
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
W+ GC++ EL T PL PG DE DQ+ I++LLG P
Sbjct: 645 WSLGCILAELLTGYPLLPGEDENDQLALIIELLGMP 680
>CE05897 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 508
Score = 88.2 bits (217), Expect = 4e-17
Identities = 70/276 (25%), Positives = 120/276 (43%), Gaps = 51/276 (18%)
Query: 28 NIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYY 87
+I RY V++ +GKGSFG V A + ++ V E ++
Sbjct: 162 HIAYRYEVLKVIGKGSFGQVIKA----------------FDHKYQQYVALKLVRNEKRFH 205
Query: 88 KKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMEC 147
++ + + D+ R ++ N++ + + F + H I E
Sbjct: 206 RQA---------DEEIRILDHLRRQDSD------GTHNIIHMLDYF--NFRNHKCITFEL 248
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYF 207
+ N+Y+L+K K + FSL +R + +L PEN+L+ R
Sbjct: 249 LSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSG 308
Query: 208 SKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDI 267
+K+ D+G + + R TY+ +R+YR+PE++L Y P+D+
Sbjct: 309 ---------------IKVIDFGSSCFDDQR--IYTYIQSRFYRAPEVILGTKY-GMPIDM 350
Query: 268 WAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
W+ GC++ EL T PL PG DE DQ+ I++LLG P
Sbjct: 351 WSLGCILAELLTGYPLLPGEDENDQLALIIELLGMP 386
>Hs5922001 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 601
Score = 87.8 bits (216), Expect = 6e-17
Identities = 93/380 (24%), Positives = 156/380 (40%), Gaps = 82/380 (21%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY + +GKGSFG V A Y + I+ ++ + + +
Sbjct: 110 RYEIDSLIGKGSFGQVVKA----------------YDHQTQELVAIKIIKNKKAFLNQAQ 153
Query: 92 I-VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQ 150
I + + +MN+ T Y +I+ + H MF + HL +V E +
Sbjct: 154 IELRLLELMNQHDTEMKY-------YIVHLKRHF-------MFRN----HLCLVFELLSY 195
Query: 151 NIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXX--XXPENILISPSHRYFS 208
N+Y L+++ R SL R + Q+ PENIL+ R
Sbjct: 196 NLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRS-- 253
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+K+ D+G + + R Y+ +R+YRSPE+LL Y +D+W
Sbjct: 254 -------------AIKIVDFGSSCQLGQR--IYQYIQSRFYRSPEVLLGTPY-DLAIDMW 297
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP-----DHSINGKEHF----GGSWLD 319
+ GC++VE+ T PLF GS+E DQ+ RI+++LG P D + +++F GG W
Sbjct: 298 SLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTL 357
Query: 320 SKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
+ +Y+ P +L++ D+V L++ P+ R I L +
Sbjct: 358 RRTKELRKDYQGPGTR-----------RLQE--DLVLRMLEYEPAAR-----ISPLGALQ 399
Query: 380 EYVMREASLAKTNNGTASKN 399
R + TN G A +
Sbjct: 400 HGFFRRTADEATNTGPAGSS 419
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 87.4 bits (215), Expect = 7e-17
Identities = 76/285 (26%), Positives = 129/285 (44%), Gaps = 45/285 (15%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFID--DSLYH------LHIVMECMEQNIYQLMKHRK 160
T +REIK + Q+ H+++V + E+ D D+L ++V E M+ ++ L++
Sbjct: 770 TAIREIKILRQL-IHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGL 828
Query: 161 RRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDN 220
FS ++S + Q++ G NIL++ S +
Sbjct: 829 VH-FSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQ--------------- 872
Query: 221 YVVKLADYGLARHVNNRS--PYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELA 278
+KLAD+GLAR N+ PYT V T WYR PE+LL + Y+ +D+W+ GC++ EL
Sbjct: 873 --IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELF 930
Query: 279 TFSPLFPGSDETDQIWRILDLLGSPDHSING---KEHFGGSWLDSKPLYQALNYEFPYVE 335
T P+F + E Q+ I L GSP ++ K + + K + L EF ++
Sbjct: 931 TKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIP 990
Query: 336 GKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ D++ L +PS+R TA + + K+
Sbjct: 991 SAAL-------------DLLDHMLTLDPSKRCTAEQTLQSDFLKD 1022
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 87.4 bits (215), Expect = 7e-17
Identities = 58/196 (29%), Positives = 94/196 (47%), Gaps = 22/196 (11%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +RE+ + + H N+VT++++ D L L +V E +++++ Q M + +
Sbjct: 403 TAIREVSLLRNL-RHANVVTLHDIIHTDRL--LTLVFEYVDRDLKQYMDSCNNAM-QMNN 458
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
+R L+Q+L G P+N+LI+ +KLAD+
Sbjct: 459 IRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGE-----------------LKLADF 501
Query: 229 GLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLAR + Y+ V T WYR P++LL YS +D+W GC++ E+ LFPG
Sbjct: 502 GLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGG 561
Query: 288 DETDQIWRILDLLGSP 303
T+Q+ I LGSP
Sbjct: 562 TPTEQLGLIFRTLGSP 577
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 87.4 bits (215), Expect = 7e-17
Identities = 58/196 (29%), Positives = 94/196 (47%), Gaps = 22/196 (11%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +RE+ + + H N+VT++++ D L L +V E +++++ Q M + +
Sbjct: 280 TAIREVSLLRNL-RHANVVTLHDIIHTDRL--LTLVFEYVDRDLKQYMDSCNNAM-QMNN 335
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
+R L+Q+L G P+N+LI+ +KLAD+
Sbjct: 336 IRLFLYQLLRGLAYCHQRRVLHRDLKPQNLLITAKGE-----------------LKLADF 378
Query: 229 GLARHVN-NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
GLAR + Y+ V T WYR P++LL YS +D+W GC++ E+ LFPG
Sbjct: 379 GLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILFEMIAGRALFPGG 438
Query: 288 DETDQIWRILDLLGSP 303
T+Q+ I LGSP
Sbjct: 439 TPTEQLGLIFRTLGSP 454
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 87.0 bits (214), Expect = 9e-17
Identities = 78/295 (26%), Positives = 136/295 (45%), Gaps = 61/295 (20%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMK-HRKRRVFSLPT- 168
+RE+ +I H+N+V++ ++ + D + +V E E ++ Q++ H + R +P
Sbjct: 59 IREMMLCREIQ-HENIVSLVQVLLKDGT--ISMVFEYAEHDLLQIIHFHSRSRTRQIPPS 115
Query: 169 -LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
L+SIL+QI+ G P NI+I+ + + VK+ D
Sbjct: 116 ILKSILWQIINGVAYLHENWIMHRDLKPANIMITATGK-----------------VKIGD 158
Query: 228 YGLARHVNNRSPYTTYVS------TRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFS 281
GL R + R P + S T WYR+PE+LL Y+ +D+WA GC+ E+ S
Sbjct: 159 LGLGRLI--RDPILPFYSSDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEMLALS 216
Query: 282 PLFPGSD-----------ETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKP-LYQALNY 329
PLF G + ++ Q+ RI++LLG+P +E + G L + P YQ ++
Sbjct: 217 PLFKGDEIKMEDKKVVPFQSTQMLRIMELLGTPT-----EERWPG--LKNYPEYYQLSSF 269
Query: 330 EFPYVEG------KTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
E Y +T+++ P D++ L+++P R TA + +F
Sbjct: 270 EVRYWNNLLPQWYQTVKNRDPQG-----LDLLMKMLQYDPKSRITAKQALEHVFF 319
>Hs5921999 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 589
Score = 87.0 bits (214), Expect = 9e-17
Identities = 78/298 (26%), Positives = 128/298 (42%), Gaps = 64/298 (21%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY + +GKGSFG V A Y + I+ ++ + + +
Sbjct: 110 RYEIDSLIGKGSFGQVVKA----------------YDHQTQELVAIKIIKNKKAFLNQAQ 153
Query: 92 I-VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQ 150
I + + +MN+ T Y +I+ + H MF + HL +V E +
Sbjct: 154 IELRLLELMNQHDTEMKY-------YIVHLKRHF-------MFRN----HLCLVFELLSY 195
Query: 151 NIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXX--XXPENILISPSHRYFS 208
N+Y L+++ R SL R + Q+ PENIL+ R
Sbjct: 196 NLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRS-- 253
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+K+ D+G + + R Y+ +R+YRSPE+LL Y +D+W
Sbjct: 254 -------------AIKIVDFGSSCQLGQR--IYQYIQSRFYRSPEVLLGTPY-DLAIDMW 297
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP-----DHSINGKEHF----GGSW 317
+ GC++VE+ T PLF GS+E DQ+ RI+++LG P D + +++F GG W
Sbjct: 298 SLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGW 355
>Hs4758222 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 629
Score = 87.0 bits (214), Expect = 9e-17
Identities = 78/298 (26%), Positives = 128/298 (42%), Gaps = 64/298 (21%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY + +GKGSFG V A Y + I+ ++ + + +
Sbjct: 110 RYEIDSLIGKGSFGQVVKA----------------YDHQTQELVAIKIIKNKKAFLNQAQ 153
Query: 92 I-VAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQ 150
I + + +MN+ T Y +I+ + H MF + HL +V E +
Sbjct: 154 IELRLLELMNQHDTEMKY-------YIVHLKRHF-------MFRN----HLCLVFELLSY 195
Query: 151 NIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXX--XXPENILISPSHRYFS 208
N+Y L+++ R SL R + Q+ PENIL+ R
Sbjct: 196 NLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRS-- 253
Query: 209 KKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
+K+ D+G + + R Y+ +R+YRSPE+LL Y +D+W
Sbjct: 254 -------------AIKIVDFGSSCQLGQR--IYQYIQSRFYRSPEVLLGTPY-DLAIDMW 297
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP-----DHSINGKEHF----GGSW 317
+ GC++VE+ T PLF GS+E DQ+ RI+++LG P D + +++F GG W
Sbjct: 298 SLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGW 355
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 87.0 bits (214), Expect = 9e-17
Identities = 76/296 (25%), Positives = 129/296 (42%), Gaps = 50/296 (16%)
Query: 112 REIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMK-HRKRRVFSLPT-- 168
REI + ++ H N++ + ++F+ S + ++ + E +++ ++K HR + P
Sbjct: 65 REIALLRELK-HPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQL 123
Query: 169 ----LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
++S+L+QIL G P NIL+ + VK
Sbjct: 124 PRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGR-------------VK 170
Query: 225 LADYGLARHVNNR----SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATF 280
+AD G AR N+ + V T WYR+PE+LL +Y+K +DIWA GC+ EL T
Sbjct: 171 IADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTS 230
Query: 281 SPLFPGSDET---------DQIWRILDLLGSPDHSINGKEHFGGSWLDSK--PLYQALNY 329
P+F E DQ+ RI ++G P W D + P Y L
Sbjct: 231 EPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADK---------DWEDIRKMPEYPTLQK 281
Query: 330 EF---PYVEGKTIRDVLPNPQLED--LYDVVTSCLKWNPSERATANEICALPYFKE 380
+F Y I+ + + D ++ ++ L +P++R T+ + PYF+E
Sbjct: 282 DFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQE 337
>Hs10190706 [T] KOG0671 LAMMER dual specificity kinases
Length = 481
Score = 87.0 bits (214), Expect = 9e-17
Identities = 64/245 (26%), Positives = 114/245 (46%), Gaps = 9/245 (3%)
Query: 140 HLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENIL 199
H+ IV E + + Y +K F + +R + +QI PENIL
Sbjct: 234 HVCIVFELLGLSTYDFIKENSFLPFQIDHIRQMAYQICQSINFLHHNKLTHTDLKPENIL 293
Query: 200 ISPSHRY--FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLR 257
S ++ K D+ N +K+ D+G A + + ++T VSTR YR+PE++L
Sbjct: 294 FVKSDYVVKYNSKMKRDERTLKNTDIKVVDFGSATYDDEH--HSTLVSTRHYRAPEVILA 351
Query: 258 KGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS-PDHSI---NGKEHF 313
G+ S+P D+W+ GC+++E +F D + + + +LG P H I +++F
Sbjct: 352 LGW-SQPCDVWSIGCILIEYYLGFTVFQTHDSKEHLAMMERILGPIPQHMIQKTRKRKYF 410
Query: 314 GGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEIC 373
+ LD A Y + + + + E L+D+V L+++P++R T +E
Sbjct: 411 HHNQLDWDEHSSAGRYVRRRCKPLKEFMLCHDEEHEKLFDLVRRMLEYDPTQRITLDEAL 470
Query: 374 ALPYF 378
P+F
Sbjct: 471 QHPFF 475
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 87.0 bits (214), Expect = 9e-17
Identities = 64/244 (26%), Positives = 111/244 (45%), Gaps = 33/244 (13%)
Query: 140 HLHIVMECMEQNIYQLMKHRKRRVFSLPT----LRSILFQILAGXXXXXXXXXXXXXXXP 195
+L++V E ++ ++ + + ++ P ++ ++FQ+ G P
Sbjct: 86 NLYLVFEYLDTDLKKFIDSYRKGPNPKPLEPFLIQKLMFQLCKGVAHCHSHGVLHRDLKP 145
Query: 196 ENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVN-NRSPYTTYVSTRWYRSPEI 254
+N+L+ D ++K+AD GL R YT + T WYR+PE+
Sbjct: 146 QNLLL----------------VKDKELLKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEV 189
Query: 255 LLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFG 314
LL +YS +D+W+ GC+ E+ LFPG E Q+ I LLG+P ++ G
Sbjct: 190 LLGSTHYSTGVDMWSVGCIFAEMVRRQALFPGDSEFQQLLHIFRLLGTPTE----QQWPG 245
Query: 315 GSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICA 374
S L +Y P E + + +P+ + + D++T LK+NP+ER +A
Sbjct: 246 VSTLRDWHVY-------PKWEPQDLTLAVPSLSPQGV-DLLTKMLKYNPAERISAKTALD 297
Query: 375 LPYF 378
PYF
Sbjct: 298 HPYF 301
>CE17062 [T] KOG0660 Mitogen-activated protein kinase
Length = 448
Score = 86.7 bits (213), Expect = 1e-16
Identities = 80/338 (23%), Positives = 144/338 (41%), Gaps = 83/338 (24%)
Query: 2 PALTLTTADSFIPPDVNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSAT 61
PA T + + ++N + +P YN ++ LG+G++G V AE
Sbjct: 23 PAPPEITPEGYHEVELNKTKWVLP-----QWYNSLKPLGEGAYGVVCTAE---------- 67
Query: 62 QISSMYPETLMDQTLIRNVEQENWYYKKKGIVAIKTMMNRLP-TLHDYTRVREIKFILQI 120
Y VAIK T+H RE+K +L+
Sbjct: 68 ------------------------YEPTGDRVAIKKFFRPFQSTIHAKRTYRELK-LLRT 102
Query: 121 PAHKNLVTIYEMFIDD----SLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQI 176
H N++ + ++F D SL +++ V M ++ +MK ++ + ++ +++Q+
Sbjct: 103 LQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQR---LTDEQIQLLIYQV 159
Query: 177 LAGXXXXXXXXXXXXXXXPENILISPSHRYFSK------------KWLEDDNYSDNY--- 221
L G + L+ P R ++ + L+ N + N
Sbjct: 160 LRGLKYMSHQNFNSTIILKK--LMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAVNERCE 217
Query: 222 ----------------VVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPL 265
K+ D+GLAR + + T YV+TRWYR+PEI+L +Y++ +
Sbjct: 218 VKVFLSFSQLSFLILSFFKILDFGLARAQD--AEMTGYVATRWYRAPEIMLNWMHYTQTV 275
Query: 266 DIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
D+W+ GC++ EL + PLFPG D DQ+ +I+ ++G+P
Sbjct: 276 DVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTP 313
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 86.7 bits (213), Expect = 1e-16
Identities = 91/389 (23%), Positives = 164/389 (41%), Gaps = 85/389 (21%)
Query: 9 ADSFIPPDVNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYP 68
A +F ++ PP +++D + ++++G+G++G V +A+ +
Sbjct: 3 AAAFGQLNLEEPPPIWGSRSVDC-FEKLEQIGEGTYGQVYMAKEI--------------- 46
Query: 69 ETLMDQTLIRNVEQENWYYKKKGIVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLV 127
K IVA+K + M+ T +REIK + ++ H+N++
Sbjct: 47 -------------------KTGEIVALKKIRMDNEREGFPITAIREIKILKKLH-HENVI 86
Query: 128 TIYEMFI------------DDSLYH--LHIVMECMEQNIYQLMKHRKRRVFSLPTLRSIL 173
+ E+ D++ Y +++V E M+ ++ L R F++P ++ +
Sbjct: 87 HLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLR-FTVPQIKCYM 145
Query: 174 FQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARH 233
Q+L G N+LI DN + +KLAD+GLAR
Sbjct: 146 KQLLTGLHYCHVNQVLHRDIKGSNLLI--------------DNEGN---LKLADFGLARS 188
Query: 234 VNN--RSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETD 291
++ T V T WYR PE+LL Y +D+W+ GC+ EL P+ PG E +
Sbjct: 189 YSHDHTGNLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLNGKPILPGKTENE 248
Query: 292 QIWRILDLLGSPDHSINGKEHFGGSW--LDSKPLYQALNYEFPYVEGKTIRDVLPNPQLE 349
Q+ +I +L GSPD S +W + P Y + P + +R++ +
Sbjct: 249 QLNKIYELCGSPDES---------NWPGVSKMPWYNQMKSSRPL--KRRVREIYRHFDRH 297
Query: 350 DLYDVVTSCLKWNPSERATANEICALPYF 378
L +++ L +PS+R A + YF
Sbjct: 298 AL-ELLEKMLVLDPSQRICAKDALDAEYF 325
>At1g74330 [D] KOG0600 Cdc2-related protein kinase
Length = 445
Score = 86.7 bits (213), Expect = 1e-16
Identities = 70/271 (25%), Positives = 119/271 (43%), Gaps = 34/271 (12%)
Query: 112 REIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRS 171
REI IL+ H N++ + + ++ +V E ME ++ L+ + F+ P ++
Sbjct: 167 REI-LILRRLNHPNIIKLEGLITSKLSCNIQLVFEYMEHDLTGLLSSPDIK-FTTPQIKC 224
Query: 172 ILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLA 231
+ Q+L+G N+L+S + ++K+AD+GLA
Sbjct: 225 YMKQLLSGLDHCHSRGVMHRDIKGSNLLLS-----------------NEGILKVADFGLA 267
Query: 232 RHVNN----RSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGS 287
N+ + P T+ V T WYR PE+LL Y +D+W+ GCV EL P+ G
Sbjct: 268 NFSNSSGHKKKPLTSRVVTLWYRPPELLLGATDYGASVDLWSVGCVFAELLLGKPILRGR 327
Query: 288 DETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQ 347
E +Q+ +I L GSP W SK L A+ ++ +R+ L +
Sbjct: 328 TEVEQLHKIFKLCGSPPEDY---------WKKSK-LPHAMLFKPQQTYDSCLRETLKDLS 377
Query: 348 LEDLYDVVTSCLKWNPSERATANEICALPYF 378
E +++ + L +P +R TA+ YF
Sbjct: 378 -ETEINLIETLLSIDPHKRGTASSALVSQYF 407
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 86.7 bits (213), Expect = 1e-16
Identities = 73/285 (25%), Positives = 126/285 (43%), Gaps = 38/285 (13%)
Query: 112 REIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRS 171
REI +L+ H N+V + + L++V + M+ ++ L + FS ++
Sbjct: 164 REI-LVLRRLDHPNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASSPVVK-FSESEVKC 221
Query: 172 ILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLA 231
++ Q+++G N+LI D V+K+AD+GLA
Sbjct: 222 LMRQLISGLEHCHSRGVLHRDIKGSNLLID-----------------DGGVLKIADFGLA 264
Query: 232 R--HVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDE 289
N++ P T+ V T WYR+PE+LL Y +D+W+ GC++ EL P+ PG E
Sbjct: 265 TIFDPNHKRPMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAELLAGRPIMPGRTE 324
Query: 290 TDQIWRILDLLGSP--DHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQ 347
+Q+ +I L GSP D+ GK G + +P +++ +T +D P+
Sbjct: 325 VEQLHKIYKLCGSPSEDYWKKGKFTHGAIYKPREPYKRSIR--------ETFKDFPPSS- 375
Query: 348 LEDLYDVVTSCLKWNPSERATANEICALPYF--KEYVMREASLAK 390
++ + L P +R TA+ +F + Y A L K
Sbjct: 376 ----LPLIDALLSIEPEDRQTASAALKSEFFTSEPYACEPADLPK 416
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 86.7 bits (213), Expect = 1e-16
Identities = 68/272 (25%), Positives = 116/272 (42%), Gaps = 36/272 (13%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REIK + ++ H +++ + + F +LH+V E ME ++ ++ R +F P
Sbjct: 55 TALREIKMLKELK-HPHIILLIDAFPHKE--NLHLVFEFMETDLEAVI--RDSNIFLSPA 109
Query: 169 -LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLAD 227
++S L G P N+LI + +KLAD
Sbjct: 110 DIKSYLLMTFKGLAYCHDKWVLHRDMKPNNLLIGVDGQ-----------------LKLAD 152
Query: 228 YGLARHVNNRS-PYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPG 286
+GLAR + + +T V RWYR+PE+L Y +D+WA C+ EL P G
Sbjct: 153 FGLARIFGSPNRKFTHQVFARWYRAPELLFGAKQYGAAVDVWAVACIFAELLLRRPFLQG 212
Query: 287 SDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNP 346
+ + DQ+ +I G+P W D L + Y+F V ++R + P
Sbjct: 213 NSDIDQLSKIFAAFGTPK---------ADQWPDLTKLPDYVEYQF--VPAPSLRSLFPAV 261
Query: 347 QLEDLYDVVTSCLKWNPSERATANEICALPYF 378
+D D+++ ++P R + + YF
Sbjct: 262 S-DDALDLLSKMFTYDPKARISIKQALEHRYF 292
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 86.3 bits (212), Expect = 2e-16
Identities = 82/351 (23%), Positives = 146/351 (41%), Gaps = 89/351 (25%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY+ I+ LG+G F +V LA+ D+ S + I+ ++ + K G
Sbjct: 4 RYDTIKHLGEGQFANVYLAQ---DLESG-------------ECVAIKKIKLGSREEAKDG 47
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
I NR T +REIK + +I H N++ + ++ + + +V + M+ +
Sbjct: 48 I-------NR-------TAIREIKLLKEIH-HDNIIGLRDVIGHRT--SIQLVFDFMDTD 90
Query: 152 IYQLMKHRKRRVFSLPT-LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKK 210
+ ++K ++ + +P +++I Q+L G P N+L++ R
Sbjct: 91 LEHVIKDKE--IILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGR----- 143
Query: 211 WLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAY 270
V TRWYR+PE+L Y +DIW+
Sbjct: 144 ---------------------------------VVTRWYRAPELLFGARSYGVGIDIWSV 170
Query: 271 GCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPL--YQALN 328
GC++ EL +P+FPG + DQ+ +I ++LG P S++ KP Y ALN
Sbjct: 171 GCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIKPQTEYMALN 230
Query: 329 YEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFK 379
Y F + +DL D++ ++P +R T + + YF+
Sbjct: 231 YYF-------------SAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYFR 268
>7301719 [T] KOG0671 LAMMER dual specificity kinases
Length = 517
Score = 86.3 bits (212), Expect = 2e-16
Identities = 87/376 (23%), Positives = 156/376 (41%), Gaps = 41/376 (10%)
Query: 8 TADSFIPPDVNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMY 67
TA I D + Y + RY ++ LG+G+FG V ++ M
Sbjct: 145 TAKPVIQDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVV-------------KVKDME 191
Query: 68 PETLMDQTLIRNVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLV 127
+ M +I+NVE+ Y++ A K +N L I Q H + +
Sbjct: 192 RDYCMALKIIKNVEK----YRE----AAKLEINALEK------------IAQKDPHCDHL 231
Query: 128 TIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXX 187
+ + D H+ IV E + +++ ++ + L +R + +Q+
Sbjct: 232 CVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNR 291
Query: 188 XXXXXXXPENILISPSH--RYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVS 245
PENIL S +++ K + N V+L D+G A + ++T VS
Sbjct: 292 LTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATF--DHEHHSTIVS 349
Query: 246 TRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDH 305
TR YR+PE++L G+ S+P D+W+ GC++ EL LF D + + + +LG +
Sbjct: 350 TRHYRAPEVILELGW-SQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPY 408
Query: 306 SINGK---EHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWN 362
+ K ++F LD A Y + + + + + +L+ ++ L++
Sbjct: 409 RMARKTKTKYFYHGKLDWDEKSSAGRYVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYE 468
Query: 363 PSERATANEICALPYF 378
PS R T E P+F
Sbjct: 469 PSSRITLGEALHHPFF 484
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 85.9 bits (211), Expect = 2e-16
Identities = 72/280 (25%), Positives = 125/280 (43%), Gaps = 41/280 (14%)
Query: 107 DYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSL 166
D + +RE+K+ LQ H N++ + ++F+ + +L++V+E + ++ ++K K +F+
Sbjct: 48 DMSAIREVKY-LQEMQHPNVIELIDIFM--AYDNLNLVLEFLPTDLEVVIKD-KSILFTP 103
Query: 167 PTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLA 226
+++ + L G P N+L SP + +K+A
Sbjct: 104 ADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQ-----------------IKVA 146
Query: 227 DYGLARHVNNRSPY---TTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPL 283
D+GLAR + +P+ T+ V TRWYR+PE+L +Y+ +DIW+ G + EL P
Sbjct: 147 DFGLARAIP--APHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPY 204
Query: 284 FPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVL 343
PG ++ DQ+ LG+P D + + Y + RD L
Sbjct: 205 LPGQNDVDQMEVTFRALGTPTDR------------DWPEVSSFMTYNKLQIYPPPSRDEL 252
Query: 344 PNPQL---EDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ E D + L NP +R TA + YFKE
Sbjct: 253 RKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKE 292
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 85.9 bits (211), Expect = 2e-16
Identities = 76/276 (27%), Positives = 112/276 (40%), Gaps = 78/276 (28%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY IQ G+G+FG V +A +TL +
Sbjct: 7 RYETIQVAGRGAFGLVVIAR-----------------DTLTSKR---------------- 33
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
VAIK +M +P + + REI + + H+N++ + + F L + IV E +
Sbjct: 34 -VAIKRIM--VPNVSKVSLAREISCLRNLH-HRNILKLLDCFPSADL--MSIVTEEVPYT 87
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
Y QIL+G PENIL++ +
Sbjct: 88 WYYT-------------------QILSGIAYLHSKEIMHRDIKPENILVTSRN------- 121
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSP---YTTYVSTRWYRSPEILLRKGYYSKPLDIW 268
VVK+AD+G A + P Y V+TRWYR+PE+L Y +DIW
Sbjct: 122 ----------VVKIADFGQACFYMPKDPNQEYDVNVATRWYRAPELLFGSKKYKPDVDIW 171
Query: 269 AYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPD 304
A GC++ EL P+FPG E +QI I +LG+P+
Sbjct: 172 AIGCILAELVRGKPIFPGRSELEQISIIFGVLGTPN 207
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 85.9 bits (211), Expect = 2e-16
Identities = 67/269 (24%), Positives = 116/269 (42%), Gaps = 32/269 (11%)
Query: 112 REIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRS 171
REI + ++ H N++ + + LH+V E ME ++ L R F+ P ++
Sbjct: 187 REINILRKLD-HPNVMKLQCLVTSKLSGSLHLVFEYMEHDLSGLAL-RPGVKFTEPQIKC 244
Query: 172 ILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLA 231
+ Q+L G N+L++ ++ V+K+ D+GLA
Sbjct: 245 FMKQLLCGLEHCHSRGILHRDIKGSNLLVN-----------------NDGVLKIGDFGLA 287
Query: 232 RHV--NNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDE 289
+ P T+ V T WYR+PE+LL Y +D+W+ GC++ EL P+ PG E
Sbjct: 288 SFYKPDQDQPLTSRVVTLWYRAPELLLGSTEYGPAIDLWSVGCILAELFVCKPIMPGRTE 347
Query: 290 TDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLE 349
+Q+ +I L GSP W +K QA +Y+ + + + + N
Sbjct: 348 VEQMHKIFKLCGSPSEEF---------WNTTK-FPQATSYKPQHPYKRVLLETFKNLSSS 397
Query: 350 DLYDVVTSCLKWNPSERATANEICALPYF 378
L D++ L P +R +A+ +F
Sbjct: 398 SL-DLLDKLLSVEPEKRCSASSTLLSEFF 425
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 85.5 bits (210), Expect = 3e-16
Identities = 87/388 (22%), Positives = 165/388 (42%), Gaps = 87/388 (22%)
Query: 11 SFIPPDVNNPPFYIPLKNIDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPET 70
SF ++ PP +++D + ++++G+G++G V +A+ +
Sbjct: 5 SFGQLNLEEPPPIWGSRSVDC-FEKLEQIGEGTYGQVYMAKEI----------------- 46
Query: 71 LMDQTLIRNVEQENWYYKKKGIVAIKTM-MNRLPTLHDYTRVREIKFILQIPAHKNLVTI 129
K IVA+K + M+ T +REIK + ++ H+N++ +
Sbjct: 47 -----------------KTGEIVALKKIRMDNEREGFPITAIREIKILKKLH-HENVIQL 88
Query: 130 YEMFI------------DDSLYH--LHIVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQ 175
E+ D++ Y +++V E M+ ++ L R F++P ++ + Q
Sbjct: 89 KEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLADRPGLR-FTVPQIKCYMKQ 147
Query: 176 ILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVN 235
+L G N+LI DN + +KLAD+GLAR +
Sbjct: 148 LLTGLHYCHVNQVLHRDIKGSNLLI--------------DNEGN---LKLADFGLARSYS 190
Query: 236 N--RSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQI 293
+ T V T WYR PE+LL Y +D+W+ GC+ EL P+ PG +E +Q+
Sbjct: 191 HDHTGNLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLHAKPILPGKNEQEQL 250
Query: 294 WRILDLLGSPDHSI---NGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLED 350
+I +L GSPD + K + ++ ++PL + + F + + +
Sbjct: 251 NKIFELCGSPDEKLWPGVSKMPWFNNFKPARPLKRRVREFFRHFDRHAL----------- 299
Query: 351 LYDVVTSCLKWNPSERATANEICALPYF 378
+++ L +P++R +A + YF
Sbjct: 300 --ELLEKMLVLDPAQRISAKDALDAEYF 325
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 85.5 bits (210), Expect = 3e-16
Identities = 77/297 (25%), Positives = 134/297 (44%), Gaps = 46/297 (15%)
Query: 89 KKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYH------LH 142
KK + K +M+ T +REI+ ILQ+ H+N+V + E+ + +
Sbjct: 74 KKFVAMKKVLMDNEKEGFPITALREIR-ILQLLKHENVVNLIEICRTKATATNGYRSTFY 132
Query: 143 IVMECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISP 202
+V + E ++ L+ + + FSL ++ ++ Q+L G N+LI+
Sbjct: 133 LVFDFCEHDLAGLLSNMNVK-FSLGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITK 191
Query: 203 SHRYFSKKWLEDDNYSDNYVVKLADYGLARHVN-----NRSPYTTYVSTRWYRSPEILLR 257
+ ++KLAD+GLAR + +++ YT V T WYR PE+LL
Sbjct: 192 -----------------HGILKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPELLLG 234
Query: 258 KGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS--PDHSINGKEHFGG 315
Y P+D+W GC++ E+ T SP+ G+ E Q+ I L GS PD
Sbjct: 235 DRNYGPPVDMWGAGCIMAEMWTRSPIMQGNTEQQQLTFISQLCGSFTPD----------- 283
Query: 316 SWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDL--YDVVTSCLKWNPSERATAN 370
W + L + E P + + +++ L P ++D D++ L +P +R A+
Sbjct: 284 VWPGVEELELYKSIELPKNQKRRVKERL-RPYVKDQTGCDLLDKLLTLDPKKRIDAD 339
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 84.7 bits (208), Expect = 5e-16
Identities = 81/292 (27%), Positives = 129/292 (43%), Gaps = 58/292 (19%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFID--DSLYH------LHIVMECMEQNIYQLMKHRK 160
T VREIK + Q+ H+N+V ++E+ D D++ ++V E M+ ++ L++
Sbjct: 847 TAVREIKILRQLN-HRNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGM 905
Query: 161 RRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDN 220
F+ SI+ Q+L G NIL++ +
Sbjct: 906 VD-FNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNNRGK--------------- 949
Query: 221 YVVKLADYGLARHVN---NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVEL 277
VKLAD+GLAR N PYT V T WYR PE+LL + Y +D+W+ GC++ EL
Sbjct: 950 --VKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCILGEL 1007
Query: 278 ATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSW--LDSKPLYQALNYEFPYVE 335
PLF + E Q+ I + GSP ++ W + PL+ L +
Sbjct: 1008 FVKRPLFQANAEMAQLETISKICGSPVPAV---------WPNVIKLPLFHTLK------Q 1052
Query: 336 GKTIR-------DVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
KT R + +P P L D++ L +P +R TA + P+ ++
Sbjct: 1053 KKTHRRRLREDFEFMPAPAL----DLLDKMLDLDPDKRITAEDALRSPWLRK 1100
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 84.7 bits (208), Expect = 5e-16
Identities = 79/302 (26%), Positives = 134/302 (44%), Gaps = 62/302 (20%)
Query: 112 REIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMK-HR------KRRVF 164
REI + ++ H+N++T+ +F+ + + ++++ E +++ ++K HR K+ V
Sbjct: 142 REIALLRELK-HQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVV 200
Query: 165 SLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
++S+L+QIL G P NIL+ + D N VK
Sbjct: 201 PRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILV-----------MGDGNERGR--VK 247
Query: 225 LADYGLARHVNNR----SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATF 280
+AD G AR N + V T WYR+PE+LL +Y+K +DIWA GC+ EL T
Sbjct: 248 IADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTS 307
Query: 281 SPLFPGSDET---------DQIWRILDLLGSPDHSINGKEHFGGSWLDSK--PLYQALNY 329
P+F E DQ+ RI +++G P W D K P + L
Sbjct: 308 EPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDK---------DWEDIKKMPEHHTLTK 358
Query: 330 EF-----------PYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
+F Y+E I+ P+ + + ++ L +P++R T+ + YF
Sbjct: 359 DFKRSTYSTCSLAKYMERHKIK---PDSK---AFHLLQKLLLMDPNKRITSEQAMQDQYF 412
Query: 379 KE 380
+E
Sbjct: 413 QE 414
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 84.3 bits (207), Expect = 6e-16
Identities = 80/293 (27%), Positives = 123/293 (41%), Gaps = 39/293 (13%)
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
+VA+K + +T +RE + + H N+V ++++ L V E M +
Sbjct: 77 LVALKVISMNAEEGVPFTAIREASLLKGLK-HANIVLLHDIIHTKET--LTFVFEYMHTD 133
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+ Q M + +R +FQ+L G P+N+LIS
Sbjct: 134 LAQYMSQHPGGLHP-HNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGE------ 186
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAY 270
+KLAD+GLAR + S Y++ V T WYR P+ LL YS LDIW
Sbjct: 187 -----------LKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGA 235
Query: 271 GCVVVELATFSPLFPG-SDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNY 329
GC+ +E+ PLFPG S+ +Q+ +I ++LG P +W L
Sbjct: 236 GCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTED---------TWPGVSKLPNYNPE 286
Query: 330 EFPYVEGKTIRDVLPN----PQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
FP +++ V P+ EDL + LK P +R +A E YF
Sbjct: 287 WFPLPTPRSLHVVWNRLGRVPEAEDL---ASQMLKGFPRDRVSAQEALVHDYF 336
>Hs21389587 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 541
Score = 84.0 bits (206), Expect = 8e-16
Identities = 80/324 (24%), Positives = 130/324 (39%), Gaps = 72/324 (22%)
Query: 33 YNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKGI 92
Y++I+ LGKG+FG V + W +
Sbjct: 11 YDIIEVLGKGTFGEVA----------------------------------KGWRRSTGEM 36
Query: 93 VAIKTMMNRLPTLHDYTRVREIKFILQI--------PAHKNLVTIYEMFIDDSLYHLHIV 144
VAIK + N D R R IK L++ P +++ E F D ++L V
Sbjct: 37 VAIKILKN------DAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYL--V 88
Query: 145 MECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH 204
E +EQN+++ K +R++ Q+L PENI++
Sbjct: 89 FELLEQNLFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQT 148
Query: 205 RYFSKKWLEDDNYSDNYVVKLADYGLARHVNN-RSPYTTYVSTRWYRSPEILLRKGYYSK 263
R + VK+ D+G A + R Y+ +R+YR+PEILL + K
Sbjct: 149 RC-------------PFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEK 195
Query: 264 PLDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPD----HSINGKEHFGG---S 316
+D+W+ GCV+ EL PL+PG++E DQ+ I + G P H+ HF +
Sbjct: 196 -VDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRMLT 254
Query: 317 WLDSKPLYQALNYEFPYVEGKTIR 340
W + + + P+V + +R
Sbjct: 255 WESHERISPSAALRHPFVSMQQLR 278
>Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases
Length = 367
Score = 84.0 bits (206), Expect = 8e-16
Identities = 88/375 (23%), Positives = 167/375 (44%), Gaps = 49/375 (13%)
Query: 29 IDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYK 88
+ RY ++ LG+G+FG V D +Q++ +IRNV + Y+
Sbjct: 29 LQERYEIVGNLGEGTFGKVV---ECLDHARGKSQVALK---------IIRNVGK----YR 72
Query: 89 KKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECM 148
+ A + +N L + + + +E KF+ V + + F H+ I E +
Sbjct: 73 E----AARLEINVLKKIKE--KDKENKFLC--------VLMSDWFNFHG--HMCIAFELL 116
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH---R 205
+N ++ +K + + LP +R + +Q+ PENIL S
Sbjct: 117 GKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETL 176
Query: 206 YFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPL 265
Y K E+ + N +++AD+G A + +TT V+TR YR PE++L G +++P
Sbjct: 177 YNEHKSCEEKSVK-NTSIRVADFGSATF--DHEHHTTIVATRHYRPPEVILELG-WAQPC 232
Query: 266 DIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS-PDHSIN---GKEHF---GGSWL 318
D+W+ GC++ E LF + + + + +LG P H I+ +++F G W
Sbjct: 233 DVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWD 292
Query: 319 DSKPLYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
++ + + ++ ++D L + Q L+D++ L+++P++R T E P+F
Sbjct: 293 ENSSDGRYVKENCKPLKSYMLQDSLEHVQ---LFDLMRRMLEFDPAQRITLAEALLHPFF 349
Query: 379 KEYVMREASLAKTNN 393
E S + N
Sbjct: 350 AGLTPEERSFHTSRN 364
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 83.6 bits (205), Expect = 1e-15
Identities = 85/329 (25%), Positives = 129/329 (38%), Gaps = 66/329 (20%)
Query: 79 NVEQENWYYKKKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSL 138
++E + KK IV+++ L T REI + ++ HKN++ + EM D S
Sbjct: 79 HLETQRQVAMKKIIVSVEK------DLFPITAQREITILKRLN-HKNIIKLIEMVYDHSP 131
Query: 139 YHLHIVMECMEQNIYQLMK----------HRKRRVFSLPTLRSILFQILAGXXXXXXXXX 188
+ + ++ Y ++ H R + +++++ QIL G
Sbjct: 132 DITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKF 191
Query: 189 XXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSP--------- 239
NILI N V+KLAD+GLAR P
Sbjct: 192 MHRDIKTANILID-----------------HNGVLKLADFGLARLYYGCPPNLKYPGGAG 234
Query: 240 ----YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDETDQIWR 295
YT+ V TRWYR+PE++L Y+ +DIW GCV E P+ G + DQ
Sbjct: 235 SGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHV 294
Query: 296 ILDLLGSPDHSINGKEHFGGSWLDSKPLYQA----LNYEFPYVEGKTIRDVLPNPQLEDL 351
I LLG+P W ++ L A NY+ T+R+ E
Sbjct: 295 IFKLLGTPTEE---------DWAVARYLPGAELTTTNYK------PTLRERFGKYLSETG 339
Query: 352 YDVVTSCLKWNPSERATANEICALPYFKE 380
D + L +P +R TA P+FKE
Sbjct: 340 LDFLGQLLALDPYKRLTAMSAKHHPWFKE 368
>Hs18765758 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 763
Score = 83.6 bits (205), Expect = 1e-15
Identities = 76/277 (27%), Positives = 118/277 (42%), Gaps = 59/277 (21%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY + +GKGSFG V A YD VEQE W
Sbjct: 158 RYEIDSLIGKGSFGQVVKA---YD-----------------------RVEQE-W------ 184
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLY---HLHIVMECM 148
VAIK + N+ L+ E++ + + H + Y + + HL +V E +
Sbjct: 185 -VAIKIIKNKKAFLNQAQI--EVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEML 241
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXX--XXPENILISPSHRY 206
N+Y L+++ R SL R Q+ PENIL+ R
Sbjct: 242 SYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRS 301
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
+K+ D+G + + R Y+ +R+YRSPE+LL Y +D
Sbjct: 302 ---------------AIKIVDFGSSCQLGQR--IYQYIQSRFYRSPEVLLGMPY-DLAID 343
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
+W+ GC++VE+ T PLF G++E DQ+ +I+++LG P
Sbjct: 344 MWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP 380
>Hs18765756 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 529
Score = 83.6 bits (205), Expect = 1e-15
Identities = 76/277 (27%), Positives = 118/277 (42%), Gaps = 59/277 (21%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY + +GKGSFG V A YD VEQE W
Sbjct: 158 RYEIDSLIGKGSFGQVVKA---YD-----------------------RVEQE-W------ 184
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLY---HLHIVMECM 148
VAIK + N+ L+ E++ + + H + Y + + HL +V E +
Sbjct: 185 -VAIKIIKNKKAFLNQAQI--EVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEML 241
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXX--XXPENILISPSHRY 206
N+Y L+++ R SL R Q+ PENIL+ R
Sbjct: 242 SYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRS 301
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
+K+ D+G + + R Y+ +R+YRSPE+LL Y +D
Sbjct: 302 ---------------AIKIVDFGSSCQLGQR--IYQYIQSRFYRSPEVLLGMPY-DLAID 343
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
+W+ GC++VE+ T PLF G++E DQ+ +I+++LG P
Sbjct: 344 MWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP 380
>Hs18765754 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 540
Score = 83.6 bits (205), Expect = 1e-15
Identities = 76/277 (27%), Positives = 118/277 (42%), Gaps = 59/277 (21%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY + +GKGSFG V A YD VEQE W
Sbjct: 158 RYEIDSLIGKGSFGQVVKA---YD-----------------------RVEQE-W------ 184
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLY---HLHIVMECM 148
VAIK + N+ L+ E++ + + H + Y + + HL +V E +
Sbjct: 185 -VAIKIIKNKKAFLNQAQI--EVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEML 241
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXX--XXPENILISPSHRY 206
N+Y L+++ R SL R Q+ PENIL+ R
Sbjct: 242 SYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRS 301
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
+K+ D+G + + R Y+ +R+YRSPE+LL Y +D
Sbjct: 302 ---------------AIKIVDFGSSCQLGQR--IYQYIQSRFYRSPEVLLGMPY-DLAID 343
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
+W+ GC++VE+ T PLF G++E DQ+ +I+++LG P
Sbjct: 344 MWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP 380
>Hs18765752 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 754
Score = 83.6 bits (205), Expect = 1e-15
Identities = 76/277 (27%), Positives = 118/277 (42%), Gaps = 59/277 (21%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY + +GKGSFG V A YD VEQE W
Sbjct: 149 RYEIDSLIGKGSFGQVVKA---YD-----------------------RVEQE-W------ 175
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLY---HLHIVMECM 148
VAIK + N+ L+ E++ + + H + Y + + HL +V E +
Sbjct: 176 -VAIKIIKNKKAFLNQAQI--EVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEML 232
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXX--XXPENILISPSHRY 206
N+Y L+++ R SL R Q+ PENIL+ R
Sbjct: 233 SYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRS 292
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
+K+ D+G + + R Y+ +R+YRSPE+LL Y +D
Sbjct: 293 ---------------AIKIVDFGSSCQLGQR--IYQYIQSRFYRSPEVLLGMPY-DLAID 334
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
+W+ GC++VE+ T PLF G++E DQ+ +I+++LG P
Sbjct: 335 MWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP 371
>Hs18765750 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 584
Score = 83.6 bits (205), Expect = 1e-15
Identities = 76/277 (27%), Positives = 118/277 (42%), Gaps = 59/277 (21%)
Query: 32 RYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYKKKG 91
RY + +GKGSFG V A YD VEQE W
Sbjct: 158 RYEIDSLIGKGSFGQVVKA---YD-----------------------RVEQE-W------ 184
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLY---HLHIVMECM 148
VAIK + N+ L+ E++ + + H + Y + + HL +V E +
Sbjct: 185 -VAIKIIKNKKAFLNQAQI--EVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEML 241
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXX--XXPENILISPSHRY 206
N+Y L+++ R SL R Q+ PENIL+ R
Sbjct: 242 SYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRS 301
Query: 207 FSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
+K+ D+G + + R Y+ +R+YRSPE+LL Y +D
Sbjct: 302 ---------------AIKIVDFGSSCQLGQR--IYQYIQSRFYRSPEVLLGMPY-DLAID 343
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
+W+ GC++VE+ T PLF G++E DQ+ +I+++LG P
Sbjct: 344 MWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP 380
>CE20405 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 83.6 bits (205), Expect = 1e-15
Identities = 67/292 (22%), Positives = 125/292 (41%), Gaps = 49/292 (16%)
Query: 113 EIKFILQIPA--HKNLVTIYEMFID--DSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
E+K + Q+ H+N+V + + + L ++ E + N+YQ +K + RR+ +
Sbjct: 70 EVKILGQLGKLKHRNIVRLLYSYQKQHEGRICLALIFEYIPLNLYQFLKDKNRRI-DIVE 128
Query: 169 LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADY 228
++ I++Q+ G P+N+L + ++ ++K++D+
Sbjct: 129 VKLIVWQLFRGQAHLEKADICHRDIKPQNLLYN----------------AETGLLKISDF 172
Query: 229 GLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSD 288
G + + +SP +Y TR+YR PE++L YY +D W+ GCV EL + G
Sbjct: 173 GSSSIQSTKSPQQSYHVTRYYRPPELILGSKYYGCKIDTWSCGCVFGELLKGGIILAGKS 232
Query: 289 ETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDV------ 342
+Q I D+LG P S + S L + L+ + Y + KT D+
Sbjct: 233 SNNQAEVIFDMLGYPTDS-----DVSSMKVSSTKLQEVLD-SYEYNKSKTTADLTYLYTQ 286
Query: 343 ----------------LPNPQLEDLYDVVTSCLKWNPSERATANEICALPYF 378
+ +++ V+ L +NP++R + EI PYF
Sbjct: 287 TVIYQKDRRTTVYNTKIEQDDMKESVAVLLQILVYNPNKRLSGIEILTHPYF 338
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 83.2 bits (204), Expect = 1e-15
Identities = 72/272 (26%), Positives = 118/272 (42%), Gaps = 34/272 (12%)
Query: 111 VREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLR 170
+REI + ++ H+N+V +Y++ ++ L +V E +Q++ + + T R
Sbjct: 49 LREICILRELK-HRNVVRLYDVVHSEN--KLTLVFEYCDQDLKKFFDSLNGYM-DAQTAR 104
Query: 171 SILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGL 230
S++ Q+L G P+N+LI+ N +KLAD+GL
Sbjct: 105 SLMLQLLRGLSFCHAHHVLHRDLKPQNLLINT-----------------NGTLKLADFGL 147
Query: 231 ARHVNNRSP-YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFS-PLFPGSD 288
AR ++ V T WYR P++L Y+ +D+W+ GC+ E++ PLFPG+D
Sbjct: 148 ARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISNAGRPLFPGAD 207
Query: 289 ETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQL 348
DQ+ RI LGSP +W L Y Y T ++PN
Sbjct: 208 VDDQLKRIFKQLGSPSED---------NWPSITQLPDYKPYPI-YHPTLTWSQIVPNLNS 257
Query: 349 EDLYDVVTSCLKWNPSERATANEICALPYFKE 380
D++ L NP+ R A+ YF +
Sbjct: 258 RG-RDLLQKLLVCNPAGRIDADAALRHAYFAD 288
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 82.8 bits (203), Expect = 2e-15
Identities = 82/298 (27%), Positives = 127/298 (42%), Gaps = 45/298 (15%)
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
+VA+K + + +T +RE + + H N+V ++++ L +V E + +
Sbjct: 142 LVALKVIRLQEEEGTPFTAIREASLLKGLK-HANIVLLHDIIHTKET--LTLVFEYVHTD 198
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+ Q M + ++ LFQ+L G P+N+LIS
Sbjct: 199 LCQYMDKHPGGLHP-DNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLIS---------- 247
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRS-PYTTYVSTRWYRSPEILLRKGYYSKPLDIWAY 270
D +KLAD+GLAR + S Y+ V T WYR P++LL YS LD+W
Sbjct: 248 -------DTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGV 300
Query: 271 GCVVVELATFSPLFPG-SDETDQIWRILDLLGSPDH----SINGKEHFGG---SWLDSKP 322
GC+ VE+ FPG D DQ+ RI +LG+P+ ++ HF + SK
Sbjct: 301 GCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKN 360
Query: 323 LYQALNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
L QA N + YV EDL + C +P R +A + YF +
Sbjct: 361 LRQAWN-KLSYVN-----------HAEDLASKLLQC---SPKNRLSAQAALSHEYFSD 403
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 82.8 bits (203), Expect = 2e-15
Identities = 75/296 (25%), Positives = 128/296 (42%), Gaps = 50/296 (16%)
Query: 112 REIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMK-HRKRRVFSLPT-- 168
REI + ++ H N++++ ++F+ + + ++ + E +++ ++K HR + P
Sbjct: 65 REIALLRELK-HPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQL 123
Query: 169 ----LRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVK 224
++S+L+QIL G P NIL+ + VK
Sbjct: 124 PRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGR-------------VK 170
Query: 225 LADYGLARHVNNR----SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATF 280
+AD G AR N+ + V T WYR+PE+LL +Y+K +DIWA GC+ EL T
Sbjct: 171 IADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTS 230
Query: 281 SPLFPGSDET---------DQIWRILDLLGSPDHSINGKEHFGGSWLDSK--PLYQALNY 329
P+F E DQ+ RI +++G P W D K P + L
Sbjct: 231 EPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADK---------DWEDIKKMPEHSTLMK 281
Query: 330 EF---PYVEGKTIRDVLPNPQLED--LYDVVTSCLKWNPSERATANEICALPYFKE 380
+F Y I+ + + D + ++ L +P +R T+ + PYF E
Sbjct: 282 DFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLE 337
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 82.8 bits (203), Expect = 2e-15
Identities = 72/285 (25%), Positives = 130/285 (45%), Gaps = 45/285 (15%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFID--DSLYH------LHIVMECMEQNIYQLMKHRK 160
T +REIK + Q+ H++++ + E+ D D+L ++V E M+ ++ L++
Sbjct: 748 TAIREIKILRQL-THQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGL 806
Query: 161 RRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDN 220
F+ ++S + Q++ G NIL++ +
Sbjct: 807 VH-FNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQ--------------- 850
Query: 221 YVVKLADYGLARHVNNRS--PYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELA 278
+KLAD+GLAR ++ PYT V T WYR PE+LL + Y+ +D+W+ GC++ EL
Sbjct: 851 --IKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELF 908
Query: 279 TFSPLFPGSDETDQIWRILDLLGSPDHSING---KEHFGGSWLDSKPLYQALNYEFPYVE 335
T P+F + E Q+ I + GSP ++ K + + K + L EF ++
Sbjct: 909 TKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIP 968
Query: 336 GKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ DL+D + L +PS+R TA + + ++
Sbjct: 969 AAAL----------DLFDYM---LALDPSKRCTAEQALQCEFLRD 1000
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 82.8 bits (203), Expect = 2e-15
Identities = 72/285 (25%), Positives = 130/285 (45%), Gaps = 45/285 (15%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFID--DSLYH------LHIVMECMEQNIYQLMKHRK 160
T +REIK + Q+ H++++ + E+ D D+L ++V E M+ ++ L++
Sbjct: 748 TAIREIKILRQL-THQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGL 806
Query: 161 RRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDN 220
F+ ++S + Q++ G NIL++ +
Sbjct: 807 VH-FNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQ--------------- 850
Query: 221 YVVKLADYGLARHVNNRS--PYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELA 278
+KLAD+GLAR ++ PYT V T WYR PE+LL + Y+ +D+W+ GC++ EL
Sbjct: 851 --IKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELF 908
Query: 279 TFSPLFPGSDETDQIWRILDLLGSPDHSING---KEHFGGSWLDSKPLYQALNYEFPYVE 335
T P+F + E Q+ I + GSP ++ K + + K + L EF ++
Sbjct: 909 TKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIP 968
Query: 336 GKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFKE 380
+ DL+D + L +PS+R TA + + ++
Sbjct: 969 AAAL----------DLFDYM---LALDPSKRCTAEQALQCEFLRD 1000
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 82.4 bits (202), Expect = 2e-15
Identities = 77/309 (24%), Positives = 129/309 (40%), Gaps = 56/309 (18%)
Query: 93 VAIKTMMNRLPTLHDYTRV-REIKFILQIPAHKNLVTIYEMFID---DSLYHLHIVMECM 148
VA+K M N L RV RE+K + H N+++ ++ D +++V E M
Sbjct: 152 VALKKMPNVFQNLVSCKRVFRELKMLCFFK-HDNVLSALDILQPPHIDYFEEIYVVTELM 210
Query: 149 EQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFS 208
+ ++++++ + S ++ L+QIL G P N+L++
Sbjct: 211 QSDLHKIIV--SPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVN------- 261
Query: 209 KKWLEDDNYSDNYVVKLADYGLAR--HVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLD 266
N V+K+ D+GLAR ++ T V T++YR+PEIL+ +YS +D
Sbjct: 262 ----------SNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAID 311
Query: 267 IWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQA 326
IW+ GC+ EL LF Q+ I DLLG+P +A
Sbjct: 312 IWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPS-------------------LEA 352
Query: 327 LNYEFPYVEGKTIRDVLPNPQLEDLYDVVTSC-----------LKWNPSERATANEICAL 375
+ + +R P L LY + + L ++PS+R +A + A
Sbjct: 353 MRTACEGAKAHILRGPHKQPSLPVLYTLSSQATHEAVHLLCRMLVFDPSKRISAKDALAH 412
Query: 376 PYFKEYVMR 384
PY E +R
Sbjct: 413 PYLDEGRLR 421
>Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 372
Score = 82.4 bits (202), Expect = 2e-15
Identities = 78/285 (27%), Positives = 133/285 (46%), Gaps = 46/285 (16%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMF-IDDSLYH-----LHIVMECMEQNIYQLMKHRKRR 162
T +REIK ILQ+ H+N+V + E+ S Y+ +++V + E ++ L+ + +
Sbjct: 62 TALREIK-ILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK 120
Query: 163 VFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYV 222
F+L ++ ++ +L G N+LI+ V
Sbjct: 121 -FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDG-----------------V 162
Query: 223 VKLADYGLARHVN---NRSP--YTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVEL 277
+KLAD+GLAR + N P YT V T WYR PE+LL + Y P+D+W GC++ E+
Sbjct: 163 LKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEM 222
Query: 278 ATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSW--LDSKPLYQALNYEFPYVE 335
T SP+ G+ E Q+ I L GS + W +D+ LY+ L E +
Sbjct: 223 WTRSPIMQGNTEQHQLALISQLCGSITPEV---------WPNVDNYELYEKL--ELVKGQ 271
Query: 336 GKTIRDVLPNPQLEDLY--DVVTSCLKWNPSERATANEICALPYF 378
+ ++D L + D Y D++ L +P++R +++ +F
Sbjct: 272 KRKVKDRL-KAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFF 315
>Hs20986508 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 277
Score = 82.0 bits (201), Expect = 3e-15
Identities = 58/235 (24%), Positives = 108/235 (45%), Gaps = 24/235 (10%)
Query: 145 MECMEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSH 204
ME M+ N+ Q+++ + +L+Q+L G P NI++
Sbjct: 1 MELMDANLCQVIQME----LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVK--- 53
Query: 205 RYFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKP 264
+ +K+ D+GLAR T YV TR+YR+PE++L GY +
Sbjct: 54 --------------SDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY-KEN 98
Query: 265 LDIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGK-EHFGGSWLDSKPL 323
+DIW+ GC++ E+ LFPG D DQ ++++ LG+P K + ++++++P
Sbjct: 99 VDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPK 158
Query: 324 YQALNYEFPYVEGKTIRDVLPNP-QLEDLYDVVTSCLKWNPSERATANEICALPY 377
Y L + + + D N + D+++ L +P++R + ++ PY
Sbjct: 159 YAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPY 213
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 82.0 bits (201), Expect = 3e-15
Identities = 65/268 (24%), Positives = 122/268 (45%), Gaps = 63/268 (23%)
Query: 109 TRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPT 168
T +REI + ++ +H+N++++ + D+L + ++ + + ++ + T
Sbjct: 46 TALREISILKKL-SHRNIISLVSIIHTDALLTM----------VFPFIDYELKKYIGMNT 94
Query: 169 LRSILF---QILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKL 225
++I+ Q++ G P+NIL++ SD V+K+
Sbjct: 95 GKNIMELVNQLICGVHYLHRMNVVHRDLKPQNILVT----------------SDG-VLKI 137
Query: 226 ADYGLARHVNNR-SPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLF 284
AD+GL+R + R PY++ V T WYRSPE+L+ Y +DIW+ GC++ E+ T PLF
Sbjct: 138 ADFGLSRSLEIRVPPYSSEVVTLWYRSPELLMGSTSYRFYVDIWSLGCIIYEMITLEPLF 197
Query: 285 PGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLP 344
PG + +Q+ I G+ S+ G + L
Sbjct: 198 PGESKENQLTLIRRKAGT-RRSLRG----------------------------MVEQRLA 228
Query: 345 NPQLEDLYDVVTSCLKWNPSERATANEI 372
P+ + +++ CL +N ++R TA+EI
Sbjct: 229 VPKF--VTEIIVRCLDFNYNQRITADEI 254
>At5g44290 [D] KOG0600 Cdc2-related protein kinase
Length = 644
Score = 82.0 bits (201), Expect = 3e-15
Identities = 102/460 (22%), Positives = 184/460 (39%), Gaps = 55/460 (11%)
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
IVA+K + L L + +++ H N++ + + L++V E M+ +
Sbjct: 162 IVALKRVRFDLSDLESVKFMAREIIVMRRLDHPNVLKLEGLITASVSSSLYLVFEYMDHD 221
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+ L + FS P ++ + Q+L+G N+LI
Sbjct: 222 LVGLASIPGIK-FSEPQVKCYMQQLLSGLHHCHSRGVLHRDIKGSNLLID---------- 270
Query: 212 LEDDNYSDNYVVKLADYGLARHVN--NRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWA 269
N V+K+AD+GLA + N P T+ V T WYR PE+LL +Y +D+W+
Sbjct: 271 -------SNGVLKIADFGLATFFDPQNCVPLTSRVVTLWYRPPELLLGACHYGVGVDLWS 323
Query: 270 YGCVVVELATFSPLFPGSDETDQIWRILDLLGSPDHSINGKEHFGGSWLDSK-PLYQALN 328
GC++ EL + P+ G E +Q+ +I L GSP W K P A
Sbjct: 324 TGCILGELYSGKPILAGKTEVEQLHKIFKLCGSPTEDY---------WRKLKLPPSAAFR 374
Query: 329 YEFPYVEGKTIRDVLPNPQLEDLYDVVTSCLKWNPSERATANEICALPYFK--EYVMREA 386
PY G+ + ++ + ++ ++ + L +P R +A YF+ + +
Sbjct: 375 PALPY--GRRVAEMFKDLP-TNVLSLLEALLSIDPDRRGSAARALESEYFRTEPFACDPS 431
Query: 387 SLAKTNNGTASKNKDNTALANKLAANPSISNQWSRILSGLPHNPELGIVP--SFNSPQKL 444
SL K SK D + P+ + R S + E ++P N+P
Sbjct: 432 SLPKY---PPSKEIDAKIRDDAKRQRPT-QEKHERQDSQTRRSHERKLIPPVKANNPSLS 487
Query: 445 PKVQKNNQMNCVTDKSQQQ--------PRRGGVASWFKFSTQKNHVNINPNTNNDEKILT 496
V+ +CV SQ+Q P G V+ +N + +N +
Sbjct: 488 TAVENPYLRSCVPGNSQRQMQDMTCNNPTSGRVSHSGPMMKNRNLSRLTYVKDNAAPRIP 547
Query: 497 SVNTNTNSQ------KNQGIVEKKQQEQQVNAHNERLDSS 530
S N+ Q +Q +++++++E + + +D+S
Sbjct: 548 SYRANSAGQGGGYVGSDQQMMDQQRKELRTFNRADTMDNS 587
>At5g39420 [D] KOG0600 Cdc2-related protein kinase
Length = 576
Score = 82.0 bits (201), Expect = 3e-15
Identities = 68/261 (26%), Positives = 119/261 (45%), Gaps = 32/261 (12%)
Query: 112 REIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQNIYQLMKHRKRRVFSLPTLRS 171
REI IL+ H N++ + + + +++V E ME ++ L + R F+ P ++
Sbjct: 151 REI-LILRKLNHPNIMKLEGIVTSRASSSIYLVFEYMEHDLAGLSSNPDIR-FTEPQIKC 208
Query: 172 ILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKWLEDDNYSDNYVVKLADYGLA 231
+ Q+L G NIL++ + V+KL D+GLA
Sbjct: 209 YMKQLLWGLEHCHMRGVIHRDIKASNILVN-----------------NKGVLKLGDFGLA 251
Query: 232 RHV--NNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYGCVVVELATFSPLFPGSDE 289
V +N++ T+ V T WYR+PE+L+ Y +D+W+ GCV E+ P+ G E
Sbjct: 252 NVVTPSNKNQLTSRVVTLWYRAPELLMGSTSYGVSVDLWSVGCVFAEILMGKPILKGRTE 311
Query: 290 TDQIWRILDLLGSPDHSINGKEHFGGSWLDSKPLYQALNYEFPYVEGKTIRDVLPNPQLE 349
+Q+ +I L GSP S W +K L A +++ + T+R+ +
Sbjct: 312 IEQLHKIYKLCGSPQDSF---------WKRTK-LPHATSFKPQHTYEATLRERCKDLSAT 361
Query: 350 DLYDVVTSCLKWNPSERATAN 370
+Y ++ + L P +R TA+
Sbjct: 362 GVY-LLETLLSMEPDKRGTAS 381
>Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases
Length = 363
Score = 82.0 bits (201), Expect = 3e-15
Identities = 87/359 (24%), Positives = 156/359 (43%), Gaps = 47/359 (13%)
Query: 29 IDARYNVIQELGKGSFGSVTLAETMYDMNSSATQISSMYPETLMDQTLIRNVEQENWYYK 88
+ RY ++ LG+G+FG V D +++ +I+NVE+ YK
Sbjct: 23 LQERYEIVSTLGEGTFGRVVQC---VDHRRGGARVALK---------IIKNVEK----YK 66
Query: 89 KKGIVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNL-VTIYEMFIDDSLYHLHIVMEC 147
+ A + +N L +++ + P +KNL V +++ F D H+ I E
Sbjct: 67 E----AARLEINVLEKINE-----------KDPDNKNLCVQMFDWF--DYHGHMCISFEL 109
Query: 148 MEQNIYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILI--SPSHR 205
+ + + +K + + +R + FQ+ PENIL S
Sbjct: 110 LGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYEL 169
Query: 206 YFSKKWLEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPL 265
++ + D+ + V++ D+G A + ++T VSTR YR+PE++L G+ S+P
Sbjct: 170 TYNLEKKRDERSVKSTAVRVVDFGSATF--DHEHHSTIVSTRHYRAPEVILELGW-SQPC 226
Query: 266 DIWAYGCVVVELATFSPLFPGSDETDQIWRILDLLGS-PDHSI---NGKEHFGGSWLDSK 321
D+W+ GC++ E LF D + + + +LG P I +++F LD
Sbjct: 227 DVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWD 286
Query: 322 PLYQALNYEFPYVEGKTIRDVLPNPQLE--DLYDVVTSCLKWNPSERATANEICALPYF 378
A Y K +R L + E L+D++ S L++ P++R T E P+F
Sbjct: 287 ENTSAGRY--VRENCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLGEALQHPFF 343
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 81.6 bits (200), Expect = 4e-15
Identities = 59/212 (27%), Positives = 99/212 (45%), Gaps = 24/212 (11%)
Query: 92 IVAIKTMMNRLPTLHDYTRVREIKFILQIPAHKNLVTIYEMFIDDSLYHLHIVMECMEQN 151
+ AIK M T +T +REIK + +K+++ + E+ ++ + +V+E M +
Sbjct: 29 VFAIKKMPVDRETGFPFTAIREIKLCKSV-INKHIIGLDEIVFEEGF--IFVVLEYMPYD 85
Query: 152 IYQLMKHRKRRVFSLPTLRSILFQILAGXXXXXXXXXXXXXXXPENILISPSHRYFSKKW 211
+ L+ + S +RSI Q++ P NIL+
Sbjct: 86 LTGLLASGAK--LSTDQIRSITSQLIEAVSSMHGMGLVHRDIKPSNILLDC--------- 134
Query: 212 LEDDNYSDNYVVKLADYGLARHVNNRSPYTTYVSTRWYRSPEILLRKGYYSKPLDIWAYG 271
+ ++KL D+GL R ++ T V T WYR+PE+LL + YS +D W+ G
Sbjct: 135 --------HGMLKLTDFGLTREISGMM--TNRVCTLWYRAPELLLGETSYSLKVDAWSVG 184
Query: 272 CVVVELATFSPLFPGSDETDQIWRILDLLGSP 303
C+++E+ P + GSDE QI I + LG P
Sbjct: 185 CIMLEMRLGRPPYRGSDEVSQIKLIFEELGIP 216
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.132 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,883,554
Number of Sequences: 60738
Number of extensions: 2180044
Number of successful extensions: 8963
Number of sequences better than 1.0e-05: 415
Number of HSP's better than 0.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 191
Number of HSP's that attempted gapping in prelim test: 8022
Number of HSP's gapped (non-prelim): 623
length of query: 755
length of database: 30,389,216
effective HSP length: 114
effective length of query: 641
effective length of database: 23,465,084
effective search space: 15041118844
effective search space used: 15041118844
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)