ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0798 good R KOG2485 General function prediction only Conserved ATP/GTP binding protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0798 272994 271840 -385
(385 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR097c [R] KOG2485 Conserved ATP/GTP binding protein 248 1e-65
SPBC25B2.04c [R] KOG2485 Conserved ATP/GTP binding protein 107 3e-23
Hs22050818 [R] KOG2485 Conserved ATP/GTP binding protein 91 2e-18
7300920 [R] KOG2485 Conserved ATP/GTP binding protein 81 3e-15
At2g41670 [R] KOG2485 Conserved ATP/GTP binding protein 68 2e-11
CE27309_1 [R] KOG2485 Conserved ATP/GTP binding protein 61 2e-09
CE02270 [R] KOG2484 GTPase 50 6e-06
SPBC26H8.08c [R] KOG2484 GTPase 49 1e-05
>YMR097c [R] KOG2485 Conserved ATP/GTP binding protein
Length = 367
Score = 248 bits (632), Expect = 1e-65
Identities = 154/370 (41%), Positives = 219/370 (58%), Gaps = 40/370 (10%)
Query: 17 STFVPRMVFPDFNIPTSDFKGHQKKAIQRAXXXXXXXXXXVELRDSRAPIATRNLIFDYL 76
S+F PR FP +++P +DFKGHQ KA++ +ELRD RAP++TRN++FD +
Sbjct: 16 SSFTPRYEFPKYSMPLTDFKGHQVKALKTFEKLLPQMNMIIELRDIRAPLSTRNVVFDRI 75
Query: 77 SL-EKKVDRLVVYTKTDQC--DPAIIASLNKWHKEMDEQYIMIDGRSKKGAKDLLHILKW 133
+ E V +LVVYT+ D + I L WH+E+ E++I++D R+K ++LL IL+W
Sbjct: 76 ARKEHDVMKLVVYTRKDLMPGNKPYIGKLKNWHEELGEKFILLDCRNKTDVRNLLKILEW 135
Query: 134 KYDKFLQKNDPGKKTVGLPLGYRMLIGGMPNVGKSTLVNSLRFTGYAGLDHSDGSKPKKV 193
+ + + + G LP+GYR LI GMPNVGKSTL+NSLR + ++ G K KKV
Sbjct: 136 Q--NYELETNGGY----LPMGYRALITGMPNVGKSTLINSLRTIFHNQVNM--GRKFKKV 187
Query: 194 AKTGDQAGVTRNTSECIRIS----DYKGGLFLYDTPGISLPAKAMSKQRMLSLSLCGCVK 249
AKTG +AGVTR TSE IR++ + + ++L DTPGI +P + RML L+LCG VK
Sbjct: 188 AKTGAEAGVTRATSEVIRVTSRNTESRNEIYLIDTPGIGVPGRVSDHNRMLGLALCGSVK 247
Query: 250 NNLVDPVIQADFLLYLLNLQ----GKYQFYTHYTTTPTNNIDILLSGLKKQVGMTNENAA 305
NNLVDP+ QAD+LLYL+NLQ G+ + Y T +PTN+I +L L+ NE +
Sbjct: 248 NNLVDPIFQADYLLYLMNLQNLNDGRTELYPGSTNSPTNDIYDVLRRLQVNKSQ-NEKST 306
Query: 306 AIYWTDSWRQGRVXXXXXXXXXXXXXXATPALFELEPILEN--FQYKKTMQEELEILKGW 363
AI WT+ WR +F+ E +L N F YK + ++LE K
Sbjct: 307 AIEWTNKWR----------------LHGKGIIFDPEVLLNNDEFSYKNYVNDQLE--KLG 348
Query: 364 DVLSQPLLNK 373
D+ + L NK
Sbjct: 349 DLSYEGLSNK 358
>SPBC25B2.04c [R] KOG2485 Conserved ATP/GTP binding protein
Length = 328
Score = 107 bits (267), Expect = 3e-23
Identities = 99/327 (30%), Positives = 153/327 (46%), Gaps = 55/327 (16%)
Query: 19 FVPRMVFPDFNIPTSDFKGHQKKAIQRAXXXXXXXXXXVELRDSRAPIATRNLIF-DYLS 77
FV R F ++ +P++ + GH K ++R VE+RD+R P+ +RN + D+L+
Sbjct: 3 FVARQTF-EYQMPSTWYPGHMNKTLKRLKNLTSSNDIFVEVRDARIPLTSRNYVMEDFLN 61
Query: 78 LEKKVDRLVVYTKTDQCDPAII-ASLNK---------------WHKEMD--EQYIMIDGR 119
K +R++VY K D D A ++K W KE E+ I
Sbjct: 62 ---KKNRIIVYNKCDLADTFHTKAKVSKHRIQNLAQQFQNVECWFKETSTPEKSAFITPY 118
Query: 120 SKKG---AKDLLHILKWKYDKFLQKNDPGKKTVGLPLGYRMLIGGMPNVGKSTLVNSLRF 176
K AK+LL +++ D Q + G+ V GMPN GKS+++NSLR
Sbjct: 119 VSKAPYFAKELLRLIRTLVD---QASANGRVYV--------YFVGMPNTGKSSILNSLRN 167
Query: 177 TGYAGLDHSDGSKPKKVAKTGDQAGVTRNTSECIRISDYKGGLFLYDTPGISLPAKAMSK 236
+ K A G+ GVT+ SE +R+ + +++ DTPGI P+
Sbjct: 168 VAL---------RKSKSAIVGNYPGVTKRISEIVRLFNDMD-VYMLDTPGIMTPS-ITKP 216
Query: 237 QRMLSLSLCGCVKNNLVDPVIQADFLLYLLNLQGKYQFYTHYTTTPTNNIDILLSGL--- 293
+ ML LSL GCVK +V PV D+LL+ LN + Y+ + + PTN++D L
Sbjct: 217 EDMLKLSLVGCVKEGIVHPVTVVDYLLFHLN-RIDPSLYSKW-SLPTNDVDEFLQNTAYK 274
Query: 294 --KKQVGMTNENAAAIYWTDSWRQGRV 318
K G +EN + Y +R GR+
Sbjct: 275 ARKLTKGGFDENFVSNYVIQQYRIGRL 301
>Hs22050818 [R] KOG2485 Conserved ATP/GTP binding protein
Length = 334
Score = 91.3 bits (225), Expect = 2e-18
Identities = 75/278 (26%), Positives = 131/278 (46%), Gaps = 37/278 (13%)
Query: 35 FKGHQKKAIQRAXXXXXXXXXXVELRDSRAPIATRNLIF-DYLSLEKKVDRLVVYTKTDQ 93
F GH K +++ +E+ D+R P++ RN +F + L L+ L+V K D
Sbjct: 31 FPGHMAKGLKKMQSSLKLVDCIIEVHDARIPLSGRNPLFQETLGLKP---HLLVLNKMDL 87
Query: 94 CDPAIIASLNKWHKEMDEQYIMIDGRSKKGAKDLLHILKWKYDKFLQKNDPGKKTVGLP- 152
D + EQ ++ +G K+++ K + Q + +G
Sbjct: 88 AD-------------LTEQQKIMQHLEGEGLKNVIFTNCVKDENVKQIIPMVTELIGRSH 134
Query: 153 -------LGYRMLIGGMPNVGKSTLVNSLRFTGYAGLDHSDGSKPKKVAKTGDQAGVTRN 205
L Y +++ G+PNVGKS+L+NSLR + K + G + G+TR
Sbjct: 135 RYHRKENLEYCIMVIGVPNVGKSSLINSLR---------RQHLRKGKATRVGGEPGITRA 185
Query: 206 TSECIRISDYKGGLFLYDTPGISLPAKAMSKQRMLSLSLCGCVKNNLVDPVIQADFLLYL 265
I++S+ + +FL DTPG+ P + S + L L+LCG V ++LV AD+LLY
Sbjct: 186 VMSKIQVSE-RPLMFLLDTPGVLAP-RIESVETGLKLALCGTVLDHLVGEETMADYLLYT 243
Query: 266 LNLQGKYQFYTHY-TTTPTNNIDILLSGLKKQVGMTNE 302
LN ++ + HY + +N++ +L + ++G T +
Sbjct: 244 LNKHQRFGYVQHYGLGSACDNVERVLKSVAVKLGKTQK 281
>7300920 [R] KOG2485 Conserved ATP/GTP binding protein
Length = 297
Score = 80.9 bits (198), Expect = 3e-15
Identities = 67/242 (27%), Positives = 122/242 (49%), Gaps = 23/242 (9%)
Query: 57 VELRDSRAPIATRNL-IFDYLSLEKKVDRLVVYTKTD----QCDPAIIASLNKWHKEMDE 111
VE+ D+R P+A RN FD ++ ++V K D + +++ L + E+
Sbjct: 19 VEIHDARIPLAGRNSQFFDTITGSGVKPHILVLNKVDLLGAKQQKSVLQQLRRQQPEL-- 76
Query: 112 QYIMIDGRSKKGAKDLLHILKWKYDKFLQKNDPGKKTVGLPLGYRMLIGGMPNVGKSTLV 171
Q+I+ + +L IL + + ++ +T + ++I G+PNVGKS+++
Sbjct: 77 QHILFTNCKDQRNNGVLDILPLA-TRLVSESSRFNRTQAAE--HNLMIIGVPNVGKSSVI 133
Query: 172 NSLRFTGYAGLDHSDGSKPKKVAKTGDQAGVTRNTSECIRISDYKGGLFLYDTPGISLPA 231
N LR K K A+ G +AG+TR+ E I+I + +++ DTPGI P+
Sbjct: 134 NVLRNVHL---------KKKSAARVGAEAGITRSVGERIKIQE-NPPVYMIDTPGILQPS 183
Query: 232 KAMSKQRMLSLSLCGCVKNNLVDPVIQADFLLYLLNLQGKYQF--YTHYTTTPTNNIDIL 289
+ M L+L GC+ +++V + AD+LLY LN KY + ++ P+++I +
Sbjct: 184 IKDDEMGM-KLALVGCLPDHIVGEDLIADYLLYWLNSHRKYDYVEMLKLSSGPSDDISAV 242
Query: 290 LS 291
L+
Sbjct: 243 LA 244
>At2g41670 [R] KOG2485 Conserved ATP/GTP binding protein
Length = 391
Score = 68.2 bits (165), Expect = 2e-11
Identities = 59/241 (24%), Positives = 112/241 (45%), Gaps = 23/241 (9%)
Query: 35 FKGHQKKAIQRAXXXXXXXXXXVELRDSRAPIATRNLIFDYLSLEKKVDRLVVYTKTDQC 94
F GH A + +E+RD+R P+++ N D S R++ K D
Sbjct: 29 FPGHMAAATRAIRNRLKLSDLVIEVRDARIPLSSANE--DLQSQMSAKRRIIALNKKDLA 86
Query: 95 DPAIIASLN--KWHKEMD---EQYIMIDGRSKKGAKDLLHILKWKYDKFLQKNDPGKKTV 149
+P ++ + KW + + + I I+ S+ LL +++ K K+ +
Sbjct: 87 NPNVLNVIRFFKWTRHFESSKQDCIAINAHSRSSVMKLLDLVELKL----------KEVI 136
Query: 150 GLPLGYRMLIGGMPNVGKSTLVNSLRFTGYAGLDHSDGSKPKKVAKTGDQAGVTRNTSEC 209
+++ G+PNVGKS L+NS+ A + K A G GVT++ +
Sbjct: 137 AREPTLLVMVVGVPNVGKSALINSIHQIAAARFPVQERLKR---ATVGPLPGVTQDIAG- 192
Query: 210 IRISDYKGGLFLYDTPGISLPAKAMSKQRMLSLSLCGCVKNNLVDPVIQADFLLYLLNLQ 269
+I+ ++ +++ D+PG+ +P+ + L L+L G VK+++V A + L +LN++
Sbjct: 193 FKIA-HRPSIYVLDSPGVLVPS-IPDIETGLKLALSGSVKDSVVGEERIAQYFLAILNIR 250
Query: 270 G 270
G
Sbjct: 251 G 251
>CE27309_1 [R] KOG2485 Conserved ATP/GTP binding protein
Length = 202
Score = 61.2 bits (147), Expect = 2e-09
Identities = 39/120 (32%), Positives = 66/120 (54%), Gaps = 10/120 (8%)
Query: 155 YRMLIGGMPNVGKSTLVNSLRFTGYAGLDHSDGSKPKKVAKTGDQAGVTRNTSECIRISD 214
Y+ ++ G+PNVGKS+L+N++R H+ G K +K + G + GVT +RI D
Sbjct: 46 YQAMVVGIPNVGKSSLINAIR-------THTLGIK-RKAVEAGARPGVTVRVQNRVRILD 97
Query: 215 YKGGLFLYDTPGISLPAKAMSKQRMLSLSLCGCVKNNLVDPVIQADFLLYLLNLQGKYQF 274
K +++ DTPG+ P + + + L++C V + V+ ADFLL+ LN + +
Sbjct: 98 -KPPVYIIDTPGVLSP-NHRNVEDAMKLAMCDLVLESHVNLYYLADFLLFWLNRSEDFSY 155
>CE02270 [R] KOG2484 GTPase
Length = 556
Score = 50.1 bits (118), Expect = 6e-06
Identities = 42/170 (24%), Positives = 76/170 (44%), Gaps = 30/170 (17%)
Query: 156 RMLIGGMPNVGKSTLVNSLRFTGYAGLDHSDGSKPKKVAKTGDQAGVTRNTSECIRISDY 215
R+ + G PNVGKS+++NSL K +K G+ G+T+ E +
Sbjct: 261 RVGVVGFPNVGKSSVINSL--------------KRRKACNVGNLPGITKEIQEV----EL 302
Query: 216 KGGLFLYDTPGISLPAKAMSKQRMLSLSLCGCVK-NNLVDPVIQADFLLYLLNLQGKYQF 274
+ L D+PG+ L ++ + ++L ++ +NL+DP+ +L + K
Sbjct: 303 DKNIRLIDSPGVILVSQ--KDLDPIEVALKNAIRVDNLLDPIAPVHAILRRCS---KETI 357
Query: 275 YTHYTTTPTNNIDILLSGLKKQVGMTNE------NAAAIYWTDSWRQGRV 318
HY N++D L+ L +++G NAAA + W G++
Sbjct: 358 MLHYNLADFNSVDQFLAQLARRIGKLRRGARPDVNAAAKRVLNDWNTGKL 407
>SPBC26H8.08c [R] KOG2484 GTPase
Length = 470
Score = 49.3 bits (116), Expect = 1e-05
Identities = 72/286 (25%), Positives = 118/286 (41%), Gaps = 49/286 (17%)
Query: 61 DSRAPIATRNLIFDYLSLEKKVDRLVVYTKTDQCDPAIIASLNKWHKEMDEQYIMIDGRS 120
D+R P TR+ + L + + ++ D LNKW + + I RS
Sbjct: 171 DARDPEGTRSKDVERQVLASSAEEKRLIFVINKIDLVPSEVLNKWVTYLRNFFPTIPMRS 230
Query: 121 KKGAKD-------------LLHILKWKYDKFLQKNDPGKKTVGLPLGYRMLIGGMPNVGK 167
G+ + + ++LK +K TVG+ +GY PNVGK
Sbjct: 231 ASGSGNSNLKHQSASASSTISNLLKSLKSYSAKKKLKSSLTVGV-IGY-------PNVGK 282
Query: 168 STLVNSLRFTGYAGLDHSDGSKPKKVAKTGDQAGVTRNTSECIRISDYKGGLFLYDTPGI 227
S+++N+L + S P G+ AG+T + E +++ + L L D+PGI
Sbjct: 283 SSVINAL-----VNRSANGRSAP---CPAGNVAGMTTSLRE-VKLDN---KLRLVDSPGI 330
Query: 228 SLPAKAMSKQRMLSLSLCGCVKNNLV-DPVIQADFLLYLLN-----LQGKYQFYTHYTTT 281
P+ + SK + L + V + V DPV A ++L L+ L+ +Q Y
Sbjct: 331 VFPS-SDSKDDLYRLVMLNAVSSTKVDDPVAVASYILQFLSRVPGQLERMFQRYELPPLL 389
Query: 282 PTNNIDILLS---------GLKKQVGMTNENAAAIYWTDSWRQGRV 318
T++ID G + G+ N NAAA + W GR+
Sbjct: 390 NTSDIDTATDFLVNIARKRGRLGRGGIPNLNAAANIVINDWHAGRI 435
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,278,054
Number of Sequences: 60738
Number of extensions: 908632
Number of successful extensions: 2157
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2138
Number of HSP's gapped (non-prelim): 8
length of query: 385
length of database: 30,389,216
effective HSP length: 108
effective length of query: 277
effective length of database: 23,829,512
effective search space: 6600774824
effective search space used: 6600774824
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)