ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0800 good R KOG3062 General function prediction only RNA polymerase II elongator associated protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0800 273193 274209 339
(339 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL110c [R] KOG3062 RNA polymerase II elongator associated protein 345 4e-95
SPAC30.02c [R] KOG3062 RNA polymerase II elongator associated pr... 193 3e-49
At1g13870 [R] KOG3062 RNA polymerase II elongator associated pro... 123 4e-28
7290238 [R] KOG3062 RNA polymerase II elongator associated protein 105 1e-22
Hs19923939 [R] KOG3062 RNA polymerase II elongator associated pr... 74 3e-13
>YKL110c [R] KOG3062 RNA polymerase II elongator associated protein
Length = 313
Score = 345 bits (886), Expect = 4e-95
Identities = 176/316 (55%), Positives = 225/316 (70%), Gaps = 8/316 (2%)
Query: 28 MPLVLLTGFPSSGKTTVAKKLVTLLQETIDSNDKLSNYSVVYHSDETLNISHDDYIGSNE 87
MPLVL TG+P SGKTT+AK LV LLQ ID+ LS YS+ YHSDE+L I H DYI S +
Sbjct: 1 MPLVLFTGYPCSGKTTLAKHLVQLLQSKIDATPSLSKYSITYHSDESLGIKHSDYITSQD 60
Query: 88 ERRARSKIMSVVKRDLSRQKVVIVDSLNYIKGFRYQLHCEVKNVMTTYCLIHTVCPMSNL 147
ER+ RS+I+S VKRDLS+ K+VIVDSLNYIKGFRYQLHCEVKN+ TT+C+I T+CP +
Sbjct: 61 ERKLRSEIISAVKRDLSKNKIVIVDSLNYIKGFRYQLHCEVKNLSTTFCVIQTLCPPETI 120
Query: 148 VEWNEKETDLHKPWESNFLNALIQRYEEPNPQTRWDSPLFTILTSQDDISTLYTDISKAI 207
EWN +T PWE LN LIQRYEEPN RWDSPLF ILT QD+I+ DI K +
Sbjct: 121 FEWN--KTSNPNPWEPELLNQLIQRYEEPNSSNRWDSPLFAILTPQDNITDYIDDICKVV 178
Query: 208 FPTVFKPATNDRDTEKILQQL-KPNNATILKAASHTNSLQILDSEASSVIKIIMKYMQQN 266
F T K A N + + + L KPN+AT+LK AS +N +Q+LD E S +IK IM +++
Sbjct: 179 FQT-SKSAKNSGHNDPLSKGLQKPNSATVLKPASQSNFIQVLDIETSKIIKTIMNHIKSL 237
Query: 267 VVSGGTS---RIILTPENTDLNDPNCLYVDLSLQN-CSMPQLQRIKRQFVAMNRLRNLEQ 322
GG S R+I++ TD+ND C +VDL + N ++ QLQR+KRQF+ N+LR+++Q
Sbjct: 238 TSIGGVSNGTRVIVSEGITDINDDGCFFVDLPIGNVVTLAQLQRLKRQFINFNKLRDIDQ 297
Query: 323 DRVKPLFVEYLNKHLN 338
DR+ PLF +YLNK+LN
Sbjct: 298 DRIGPLFADYLNKNLN 313
>SPAC30.02c [R] KOG3062 RNA polymerase II elongator associated protein
Length = 281
Score = 193 bits (490), Expect = 3e-49
Identities = 114/308 (37%), Positives = 171/308 (55%), Gaps = 35/308 (11%)
Query: 28 MPLVLLTGFPSSGKTTVAKKLVTLLQETIDSN-DKLSNYSVVYHSDETLNISHDDYIGSN 86
MPL++++G+PSSGKTT + +L L++ I N D +Y V+ +DE+LNI + Y S
Sbjct: 1 MPLIIVSGYPSSGKTTRSNELKKALEDRIHQNIDNTKDYRVIIINDESLNIEKETYRESK 60
Query: 87 EERRARSKIMSVVKRDLSRQKVVIVDSLNYIKGFRYQLHCEVKNVMTTYCLIHTVCPMSN 146
E+ AR + S V+R+LS+ VI D+LNYIKGFRYQL+CE K++ TT+C+IH P
Sbjct: 61 NEKAARGLLYSAVQRELSKSTFVICDALNYIKGFRYQLYCESKSMYTTHCVIHVAVPQDL 120
Query: 147 LVEWNEKETDLHKPWESNFLNALIQRYEEPNPQTRWDSPLFTILTSQDDISTLYTDISKA 206
++N + +P+ + L L+ RYEEPN TRWDSPLFT+L DD S DI
Sbjct: 121 CRKFNSNK---EQPYPDDVLEQLMFRYEEPNGMTRWDSPLFTVL--HDDASCPIDDIWSV 175
Query: 207 IFPTVFKPATNDRDTEKILQQLKPNNATILKAASHTNSLQILDSEASSVIKIIMKYMQQN 266
+ + +KPN AT++K + N L LD VI +I+
Sbjct: 176 LIHN---------------KNVKPNQATMVKPPAEVNYLYELDKTTQDVIMLILD----- 215
Query: 267 VVSGGTSRIILTPENTDLNDPNCLYVDLSLQNCSMPQLQRIKRQFVAMNRLRNLEQDRVK 326
+ + +I P + L + L S+P LQR++RQF+ +NR ++ + +K
Sbjct: 216 --NSNDTSLITVPGSK-------LQIALPSVTVSLPLLQRLRRQFIQINRQQSYNTNVLK 266
Query: 327 PLFVEYLN 334
+FVE+LN
Sbjct: 267 EMFVEFLN 274
>At1g13870 [R] KOG3062 RNA polymerase II elongator associated protein
Length = 302
Score = 123 bits (308), Expect = 4e-28
Identities = 91/316 (28%), Positives = 150/316 (46%), Gaps = 29/316 (9%)
Query: 28 MPLVLLTGFPSSGKTTVAKKLVTLLQETIDSNDKLSNYSVVYHSDETLNISHDDYIGSNE 87
M LV++ G P SGK+ A L L+E+ +H D N Y
Sbjct: 1 MALVVICGQPCSGKSIAAVTLAETLKESETKQSVRIIDEASFHLDRNQN-----YANMPA 55
Query: 88 ERRARSKIMSVVKRDLSRQKVVIVDSLNYIKGFRYQLHCEVKNVMTTYCLIHTVCPMSNL 147
E+ R K+ S V R +S ++VIVDSLN IKG+RY+L C + YC+++ ++
Sbjct: 56 EKNLRGKLRSDVDRSVSTGEIVIVDSLNSIKGYRYELWCIARAAGIRYCVVYCDVDEAHC 115
Query: 148 VEWNEKETDLHKP-WESNFLNALIQRYEEPNPQTRWDSPLFTILTSQDDISTLYTDISKA 206
+WN++ +D + ++ L++R+E+P + RWDSPLF + S++ I I +A
Sbjct: 116 RQWNKERSDRGEDGYDDGIFEDLVRRFEKPERRNRWDSPLFELYPSREVIDKSSPVILEA 175
Query: 207 IFPTVFKPATNDRDTEKILQQLKPNNATILKAASHTNSLQILDSEASSVIKIIMKYMQQN 266
+ + T D T+ + + L+P+ AT S NSL LD +I I ++Q
Sbjct: 176 V---TYLTKTVDSKTQDV-RILQPSIATQAARFSEANSLYELDRATQEIINAI---VEQQ 228
Query: 267 VVSGGTSRIILTPENTDLNDPNCLYVDLSLQNCSMPQLQRIKRQFVAMNRLRNL------ 320
+ SR+ L E + + +P+L+R++R FV + +L
Sbjct: 229 SLGAAISRVTLGNELPPIE---------ICRPIGLPELRRLRRTFVKLMGQSSLSGPPLP 279
Query: 321 -EQDRVKPLFVEYLNK 335
+ D K FV+YLN+
Sbjct: 280 TDADSAKRRFVDYLNR 295
>7290238 [R] KOG3062 RNA polymerase II elongator associated protein
Length = 299
Score = 105 bits (261), Expect = 1e-22
Identities = 93/328 (28%), Positives = 148/328 (44%), Gaps = 56/328 (17%)
Query: 28 MPLVLLTGFPSSGKTTVAKKLVTLLQETIDSNDKLSNYSVVYHSDETLNISHDDYIGSNE 87
MPLV++TG P+SGK+T A++L E +S V + N D S +
Sbjct: 1 MPLVVITGLPASGKSTRARQLRDHFVERGRKVHLISENEAVPKAGFGKNSHTGD---SQK 57
Query: 88 ERRARSKIMSVVKRDLSRQKVVIVDSLNYIKGFRYQLHCEVKNVMTTYCLIHTVCPMSNL 147
E+ RS + S R L+++ +VI+D+ NYIKG+RY+L+C K TT C + T P
Sbjct: 58 EKVVRSDLKSEASRHLNQEDLVILDAGNYIKGYRYELYCMSKVSRTTQCTVFTCIPQEEA 117
Query: 148 VEWNEKET----------------DLHKPWESNFLNALIQRYEEPNPQTRWDSPLFTILT 191
+N + T + P+ +AL QRYEEP RWDSPL +L
Sbjct: 118 WTFNSQRTAPDELPGDSERVQPVDNSDVPYTRETFDALCQRYEEPQSNNRWDSPLVVVLP 177
Query: 192 SQD-DISTLYTDISKAIFPTVFKPATNDRDTEKILQQLKPNNATILKAASHTNSLQILDS 250
D+ +Y KA++ + Q L PN +T TN L LD
Sbjct: 178 KDTLDMEAIY----KALYES---------------QPLPPNQSTYNAPLGTTNYLFELDK 218
Query: 251 EASSVIKIIMKYMQQNVVSGGTSRIILTPENTDLNDPNCLYVDLSLQNCSMPQLQRIKRQ 310
++IK I+ ++ + + G RI N + V S+ + QL R++++
Sbjct: 219 IVQAIIKEILGAVK--IKAFGQLRI--------PGSRNPVKVATSM---NALQLNRLRQK 265
Query: 311 FVA----MNRLRNLEQDRVKPLFVEYLN 334
F+ ++ ++V LFV+++N
Sbjct: 266 FITSTCHASQTSPTPLEQVPHLFVQFIN 293
>Hs19923939 [R] KOG3062 RNA polymerase II elongator associated protein
Length = 354
Score = 73.9 bits (180), Expect = 3e-13
Identities = 46/119 (38%), Positives = 64/119 (53%), Gaps = 12/119 (10%)
Query: 28 MPLVLLTGFPSSGKTTVAKKLVTLLQETIDSNDKLSNYSVVYHSDETLNISHDD---YIG 84
MPLV+ G P SGK+ A++L L + VY D+ + +D Y
Sbjct: 1 MPLVVFCGLPYSGKSRRAEELRVALA---------AEGRAVYVVDDAAVLGAEDPAVYGD 51
Query: 85 SNEERRARSKIMSVVKRDLSRQKVVIVDSLNYIKGFRYQLHCEVKNVMTTYCLIHTVCP 143
S E+ R + + V+R LSR VVI+DSLNYIKGFRY+L+C + T CL++ V P
Sbjct: 52 SAREKALRGALRASVERRLSRHDVVILDSLNYIKGFRYELYCLARAARTPLCLVYCVRP 110
Score = 49.3 bits (116), Expect = 8e-06
Identities = 42/180 (23%), Positives = 80/180 (44%), Gaps = 31/180 (17%)
Query: 161 WESNFLNALIQRYEEPNPQTRWDSPLFTILTSQDDISTLYTDISKAIFPTVFKPATNDRD 220
+ L AL R+E P+ + RWD PLFT++ ++ + I A+F P
Sbjct: 204 YSPELLEALTLRFEAPDSRNRWDRPLFTLVGLEEPLP--LAGIRSALFENRAPP------ 255
Query: 221 TEKILQQLKPNNATILKAASHTNSLQILDSEASSVIKIIMKYMQQNVVSGGTSRIILTPE 280
P+ +T + + + L LD S V+ +M+ Q++ V G + T E
Sbjct: 256 ---------PHQSTQSQPLASGSFLHQLDQVTSQVLAGLME-AQKSAVPGDLLTLPGTTE 305
Query: 281 NTDLNDPNCLYVDLSLQNCSMPQLQRIKRQFVAMNRL--RNLEQDRVKPLFVEYLNKHLN 338
+ P +M +L R++RQF++ ++ N ++ +F++YL++ L+
Sbjct: 306 HLRFTRP-----------LTMAELSRLRRQFISYTKMHPNNENLPQLANMFLQYLSQSLH 354
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,770,168
Number of Sequences: 60738
Number of extensions: 828829
Number of successful extensions: 3003
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2984
Number of HSP's gapped (non-prelim): 6
length of query: 339
length of database: 30,389,216
effective HSP length: 107
effective length of query: 232
effective length of database: 23,890,250
effective search space: 5542538000
effective search space used: 5542538000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)