ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0815 good L KOG2519 Replication, recombination and repair 5'-3' exonuclease
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0815 278441 279583 381
(381 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL113c [L] KOG2519 5'-3' exonuclease 502 e-142
SPAC3G6.06c [L] KOG2519 5'-3' exonuclease 411 e-115
Hs4758356 [L] KOG2519 5'-3' exonuclease 385 e-107
7302871 [L] KOG2519 5'-3' exonuclease 370 e-102
CE22109 [L] KOG2519 5'-3' exonuclease 355 6e-98
At5g26675 [L] KOG2519 5'-3' exonuclease 335 9e-92
ECU03g1080 [L] KOG2519 5'-3' exonuclease 280 3e-75
YGR258c [L] KOG2520 5'-3' exonuclease 99 8e-21
7295491 [L] KOG2519 5'-3' exonuclease 88 2e-17
Hs4503601 [L] KOG2520 5'-3' exonuclease 85 2e-16
YDR263c [L] KOG2518 5'-3' exonuclease 84 3e-16
Hs18491020 [L] KOG2518 5'-3' exonuclease 83 8e-16
Hs18491018 [L] KOG2518 5'-3' exonuclease 83 8e-16
Hs18491016 [L] KOG2518 5'-3' exonuclease 83 8e-16
SPBC29A10.05 [L] KOG2518 5'-3' exonuclease 82 1e-15
SPBC3E7.08c [L] KOG2520 5'-3' exonuclease 81 2e-15
ECU11g0760 [L] KOG2518 5'-3' exonuclease 79 9e-15
At1g29630 [L] KOG2518 5'-3' exonuclease 77 4e-14
SPAC12G12.16c [L] KOG2519 5'-3' exonuclease 75 1e-13
At3g28030 [L] KOG2520 5'-3' exonuclease 75 1e-13
7297419 [L] KOG2520 5'-3' exonuclease 74 4e-13
YOR033c [L] KOG2518 5'-3' exonuclease 74 5e-13
At1g01880 [L] KOG2519 5'-3' exonuclease 71 2e-12
ECU09g1620 [L] KOG2520 5'-3' exonuclease 70 7e-12
CE11308 [L] KOG2520 5'-3' exonuclease 70 7e-12
At1g18090 [L] KOG2518 5'-3' exonuclease 63 6e-10
CE01401 [L] KOG2520 5'-3' exonuclease 62 2e-09
7298467 [L] KOG2518 5'-3' exonuclease 55 2e-07
CE28728 [L] KOG2518 5'-3' exonuclease 54 4e-07
YER041w [L] KOG2520 5'-3' exonuclease 52 1e-06
>YKL113c [L] KOG2519 5'-3' exonuclease
Length = 382
Score = 502 bits (1293), Expect = e-142
Identities = 247/357 (69%), Positives = 290/357 (81%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGIK L +ISE VP+AI+ DIK F GRKVAIDASMSLYQFLIAVRQQDG QL E GE
Sbjct: 1 MGIKGLNAIISEHVPSAIRKSDIKSFFGRKVAIDASMSLYQFLIAVRQQDGGQLTNEAGE 60
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQAE 120
TTSHLMGMFYRTLRMID+GIKPCYVFDG PP+LK +EL KR RR +TE KL EAT + E
Sbjct: 61 TTSHLMGMFYRTLRMIDNGIKPCYVFDGKPPDLKSHELTKRSSRRVETEKKLAEATTELE 120
Query: 121 IIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASEDMDT 180
+K ERRLVKV HNEEAQKLL LMGIPY++AP EAEAQCAELAK GKV+AAASEDMDT
Sbjct: 121 KMKQERRLVKVSKEHNEEAQKLLGLMGIPYIIAPTEAEAQCAELAKKGKVYAAASEDMDT 180
Query: 181 LCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGIKGVG 240
LCY+TP LLRHLTFSEA+K PI E DT+++ LDLT QF+DL I+LGCDYCE I+GVG
Sbjct: 181 LCYRTPFLLRHLTFSEAKKEPIHEIDTELVLRGLDLTIEQFVDLCIMLGCDYCESIRGVG 240
Query: 241 PVNALKLIKEHGSLEAIVEKFENGDISSGRWKIPEGWQFKEARDLFMQPDVIPSEEVTLK 300
PV ALKLIK HGS+E IVE E+G+ ++ +WKIPE W +K+AR LF+ P+VI E+ LK
Sbjct: 241 PVTALKLIKTHGSIEKIVEFIESGESNNTKWKIPEDWPYKQARMLFLDPEVIDGNEINLK 300
Query: 301 WEEPKAEELIEFMVKEKGFNEDRIKSGIERLRKGLKVGVQKRLDSFFKIQPKTKEEL 357
W PK +ELIE++ +K F+E+R+KSGI RL+KGLK G+Q RLD FF++ PKTKE+L
Sbjct: 301 WSPPKEKELIEYLCDDKKFSEERVKSGISRLKKGLKSGIQGRLDGFFQVVPKTKEQL 357
>SPAC3G6.06c [L] KOG2519 5'-3' exonuclease
Length = 380
Score = 411 bits (1057), Expect = e-115
Identities = 209/360 (58%), Positives = 265/360 (73%), Gaps = 10/360 (2%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGIK LA ++SE P ++K DIK + GRKVAIDASMSLYQFLI VR QDG QL E GE
Sbjct: 1 MGIKGLAQVLSEHAPASVKHNDIKNYFGRKVAIDASMSLYQFLIQVRSQDGQQLMNEQGE 60
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVR----REDTEAKLKEAT 116
TTSHLMGMFYRTLR++D+GIKPC+VFDG PP LK EL KR R RED E + KE
Sbjct: 61 TTSHLMGMFYRTLRIVDNGIKPCFVFDGKPPTLKSGELAKRVARHQKAREDQE-ETKEVG 119
Query: 117 EQAEIIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASE 176
+ + +R VKV HN+EA++LL LMGIP+V AP EAEAQCA LA+SGKV+AAASE
Sbjct: 120 TAEMVDRFAKRTVKVTRQHNDEAKRLLELMGIPFVNAPCEAEAQCAALARSGKVYAAASE 179
Query: 177 DMDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGI 236
DMDTLC+Q PVLLRHLTFSE RK PI E++ + N LD++ QF+DL I+LGCDYCE I
Sbjct: 180 DMDTLCFQAPVLLRHLTFSEQRKEPISEYNIEKALNGLDMSVEQFVDLCILLGCDYCEPI 239
Query: 237 KGVGPVNALKLIKEHGSLEAIVEKFENGDISSGRWKIPEGWQFKEARDLFMQPDVIPSEE 296
+GVGP A++LI+++G+L+ V++ + ++ IPE W +++AR LF+ +V+P EE
Sbjct: 240 RGVGPARAVELIRQYGTLDRFVKEADR-----SKYPIPEDWPYEDARRLFLDAEVLPGEE 294
Query: 297 VTLKWEEPKAEELIEFMVKEKGFNEDRIKSGIERLRKGLKVGVQKRLDSFFKIQPKTKEE 356
+ LKW+ P A+ +I+F+VKEKGFNEDR+K GI RL K K Q RLDSFFK P + ++
Sbjct: 295 IELKWKSPDADGIIQFLVKEKGFNEDRVKLGINRLEKASKTIPQGRLDSFFKPVPSSPKK 354
>Hs4758356 [L] KOG2519 5'-3' exonuclease
Length = 380
Score = 385 bits (989), Expect = e-107
Identities = 199/352 (56%), Positives = 255/352 (71%), Gaps = 9/352 (2%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGI+ LA LI++ P+AI+ DIK + GRKVAIDASMS+YQFLIAVRQ V L E+GE
Sbjct: 1 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDV-LQNEEGE 59
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATE--- 117
TTSHLMGMFYRT+RM+++GIKP YVFDG PP+LK EL KR RR + E +L++A
Sbjct: 60 TTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGA 119
Query: 118 QAEIIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASED 177
+ E+ K +RLVKV HN+E + LLSLMGIPY+ AP+EAEA CA L K+GKV+AAA+ED
Sbjct: 120 EQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATED 179
Query: 178 MDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGIK 237
MD L + +PVL+RHLT SEA+KLPIQEF I L L Q QF+DL I+LG DYCE I+
Sbjct: 180 MDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIR 239
Query: 238 GVGPVNALKLIKEHGSLEAIVEKFENGDISSGRWKIPEGWQFKEARDLFMQPDVIPSEEV 297
G+GP A+ LI++H S+E IV + + ++ +PE W KEA LF++P+V+ E V
Sbjct: 240 GIGPKRAVDLIQKHKSIEEIVRR-----LDPNKYPVPENWLHKEAHQLFLEPEVLDPESV 294
Query: 298 TLKWEEPKAEELIEFMVKEKGFNEDRIKSGIERLRKGLKVGVQKRLDSFFKI 349
LKW EP EELI+FM EK F+E+RI+SG++RL K + Q RLD FFK+
Sbjct: 295 ELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKV 346
>7302871 [L] KOG2519 5'-3' exonuclease
Length = 385
Score = 370 bits (950), Expect = e-102
Identities = 186/356 (52%), Positives = 255/356 (71%), Gaps = 9/356 (2%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGI L+ LI++ P AI+ ++K+F GRKVAIDASM LYQFLIAVR + G QLA +G+
Sbjct: 1 MGILGLSKLIADLAPQAIRESEMKHFFGRKVAIDASMCLYQFLIAVRSE-GAQLATVNGD 59
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATE--- 117
TSHLMGMFYRT+R++D+GIKP YVFDG PP+LK EL KR RRE+ E LK AT+
Sbjct: 60 PTSHLMGMFYRTIRLLDNGIKPVYVFDGKPPDLKSGELAKRAERREEAEKALKAATDAGD 119
Query: 118 QAEIIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASED 177
A I K RRLV+V H +EA++LL+LMG+PYV AP EAEAQCA L K+GKV+A A+ED
Sbjct: 120 DAGIEKFNRRLVRVTKEHAKEAKELLTLMGVPYVDAPCEAEAQCAALVKAGKVYATATED 179
Query: 178 MDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGIK 237
MD L + + LLR+LT+SEARK+P++EF D + L + +FIDL I+LGCDYCE IK
Sbjct: 180 MDALTFGSTKLLRYLTYSEARKMPVKEFSYDKLLEGLAINNREFIDLCILLGCDYCESIK 239
Query: 238 GVGPVNALKLIKEHGSLEAIVEKFENGDISSGRWKIPEGWQFKEARDLFMQPDVIPSEEV 297
G+GP A++LI + +E I++ ++ S ++ +PE W +K AR+LF++P+V ++ +
Sbjct: 240 GIGPKRAIELINTYRDIETILD-----NLDSSKYTVPENWNYKVARELFIEPEVADADSI 294
Query: 298 TLKWEEPKAEELIEFMVKEKGFNEDRIKSGIERLRKGLKVGVQKRLDSFFKIQPKT 353
LKW EP E L++F+ ++ FNE+R+++G ++L K + Q RLDSFFK P T
Sbjct: 295 DLKWVEPDEEGLVKFLCGDRQFNEERVRNGAKKLMKSKQAQTQVRLDSFFKTLPST 350
>CE22109 [L] KOG2519 5'-3' exonuclease
Length = 382
Score = 355 bits (911), Expect = 6e-98
Identities = 183/350 (52%), Positives = 243/350 (69%), Gaps = 9/350 (2%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGIK L+ +I++ P+AIK ++K F GR VAIDASM LYQFLIAVRQ DG QL EDGE
Sbjct: 1 MGIKGLSQVIADNAPSAIKVNEMKAFFGRTVAIDASMCLYQFLIAVRQ-DGSQLQSEDGE 59
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQAE 120
TTSHLMGM RT+RM ++G+KP YVFDG PP++K EL+KR RR + E L EA E+ +
Sbjct: 60 TTSHLMGMLNRTVRMFENGVKPVYVFDGKPPDMKGGELEKRSERRAEAEKALTEAKEKGD 119
Query: 121 II---KHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASED 177
+ K ERRLVKV N+EA++LL LMGIP V AP EAEAQCA L K+GKVF +ED
Sbjct: 120 VKEAEKFERRLVKVTKQQNDEAKRLLGLMGIPVVEAPCEAEAQCAHLVKAGKVFGTVTED 179
Query: 178 MDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGIK 237
MD L + + VLLRH A+K+PI+EF+ + + L+ +FIDL I+LGCDYC I+
Sbjct: 180 MDALTFGSTVLLRHFLAPVAKKIPIKEFNLSLALEEMKLSVEEFIDLCILLGCDYCGTIR 239
Query: 238 GVGPVNALKLIKEHGSLEAIVEKFENGDISSGRWKIPEGWQFKEARDLFMQPDVIPSEEV 297
GVGP A++LI++H ++E I+E +I ++ PE W +K AR+LF+ P+V EEV
Sbjct: 240 GVGPKKAVELIRQHKNIETILE-----NIDQNKYPPPEDWPYKRARELFLNPEVTKPEEV 294
Query: 298 TLKWEEPKAEELIEFMVKEKGFNEDRIKSGIERLRKGLKVGVQKRLDSFF 347
L W+E E +I+F+ EK FNE+RI++ + +L+ K G Q R+DSFF
Sbjct: 295 ELTWKEADVEGVIQFLCGEKNFNEERIRNALAKLKTSRKSGTQGRIDSFF 344
>At5g26675 [L] KOG2519 5'-3' exonuclease
Length = 465
Score = 335 bits (858), Expect = 9e-92
Identities = 173/364 (47%), Positives = 235/364 (64%), Gaps = 21/364 (5%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGIK L L+++ P+ +K + + + GRK+A+DASMS+YQFLI V + L E GE
Sbjct: 1 MGIKGLTKLLADNAPSCMKEQKFESYFGRKIAVDASMSIYQFLIVVGRTGTEMLTNEAGE 60
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLK---EATE 117
TSHL GMF RT+R+++ GIKP YVFDG PPELK+ EL KR +R D A L EA
Sbjct: 61 VTSHLQGMFNRTIRLLEAGIKPVYVFDGKPPELKRQELAKRYSKRADATADLTGAIEAGN 120
Query: 118 QAEIIKHERRLVKVLPWHNEEAQKLLSLMGIP------------YVVAPAEAEAQCAELA 165
+ +I K+ +R VKV HN++ ++LL LMG+P Y+ A +EAEAQCA L
Sbjct: 121 KEDIEKYSKRTVKVTKQHNDDCKRLLRLMGVPVVEFEKKTDVASYIQATSEAEAQCAALC 180
Query: 166 KSGKVFAAASEDMDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLG 225
KSGKV+ ASEDMD+L + P LRHL +RK+P+ EF+ I L LT QFIDL
Sbjct: 181 KSGKVYGVASEDMDSLTFGAPKFLRHLMDPSSRKIPVMEFEVAKILEELQLTMDQFIDLC 240
Query: 226 IILGCDYCEGIKGVGPVNALKLIKEHGSLEAIVEKFENGDISSGRWKIPEGWQFKEARDL 285
I+ GCDYC+ I+G+G ALKLI++HGS+E I+E +++ R++IPE W + EAR L
Sbjct: 241 ILSGCDYCDSIRGIGGQTALKLIRQHGSIETILE-----NLNKERYQIPEEWPYNEARKL 295
Query: 286 FMQPDVIPSEE-VTLKWEEPKAEELIEFMVKEKGFNEDRIKSGIERLRKGLKVGVQKRLD 344
F +PDVI EE + +KW P E +++F+V E GFN DR+ IE+++ Q RL+
Sbjct: 296 FKEPDVITDEEQLDIKWTSPDEEGIVQFLVNENGFNIDRVTKAIEKIKTAKNKSSQGRLE 355
Query: 345 SFFK 348
SFFK
Sbjct: 356 SFFK 359
>ECU03g1080 [L] KOG2519 5'-3' exonuclease
Length = 345
Score = 280 bits (715), Expect = 3e-75
Identities = 150/350 (42%), Positives = 221/350 (62%), Gaps = 14/350 (4%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGIK L+ L+ E I+ R + Y+ +KVAIDASMS+YQFLIAVR G L ED
Sbjct: 1 MGIKQLSKLLRENSKRGIRERPLVYYSSKKVAIDASMSMYQFLIAVRS-GGATLGNEDSP 59
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQAE 120
T SHL+G FYRT+RM++ GI P YVFDG PPE+K EL+KRK RR + + +EA+E +
Sbjct: 60 T-SHLVGFFYRTIRMVELGITPVYVFDGVPPEIKMKELEKRKERRAAADREYREASEVGD 118
Query: 121 ---IIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASED 177
+ +++R KV H +E ++LL LMGIP+ AP+EAEA CA L K V+ A+ED
Sbjct: 119 KELMEMYDKRKTKVTGVHVDECKRLLGLMGIPFETAPSEAEAYCALLCKKKAVYGVATED 178
Query: 178 MDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGIK 237
MD L + +PV+LR+ +++++LP+ E + I L L ++FIDL I+LGCDYC +K
Sbjct: 179 MDALTFGSPVVLRNFNGTQSKRLPVMEHNLPQILEDLSLDHSEFIDLCILLGCDYCSTLK 238
Query: 238 GVGPVNALKLIKEHGSLEAIVEKFENGDISSGRWKIPEGWQFKEARDLF-MQPDVIPSEE 296
G+GP AL LIK+H S+ I+ +N D+ ++P W++ +A+ +F ++ +
Sbjct: 239 GIGPKKALGLIKKHRSIGNIL---KNEDL-----EVPGDWRYSDAQKIFGSLAEIGEIRD 290
Query: 297 VTLKWEEPKAEELIEFMVKEKGFNEDRIKSGIERLRKGLKVGVQKRLDSF 346
+ W+ ++ F+V+EKGF+ +R+ GI++L K G Q RLD F
Sbjct: 291 FNISWDSIDRNGIVNFLVEEKGFDLERVNKGIDKLINSRKKGTQGRLDCF 340
>YGR258c [L] KOG2520 5'-3' exonuclease
Length = 1031
Score = 99.4 bits (246), Expect = 8e-21
Identities = 69/235 (29%), Positives = 117/235 (49%), Gaps = 29/235 (12%)
Query: 137 EEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASEDMDTLCYQTPVLLRHLTFSE 196
+E Q+LLS GIPY+ AP EAEAQCAEL + V ++D D + + +++ F E
Sbjct: 773 KEVQELLSRFGIPYITAPMEAEAQCAELLQLNLVDGIITDDSDVFLFGGTKIYKNM-FHE 831
Query: 197 ARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGIKGVGPVNALKLIKEHGSLEA 256
K ++ +D + I L L + I+L +LG DY G+KG+GPV+++++I E G+L+
Sbjct: 832 --KNYVEFYDAESILKLLGLDRKNMIELAQLLGSDYTNGLKGMGPVSSIEVIAEFGNLKN 889
Query: 257 IVEKFENGDISSGRWKIPEGWQFKEAR--------------------DLFMQPDVIPSEE 296
+ + NG + + ++ K+ R D +M+P+V +
Sbjct: 890 FKDWYNNGQFDKRKQETENKFE-KDLRKKLVNNEIILDDDFPSVMVYDAYMRPEV-DHDT 947
Query: 297 VTLKWEEPKAEELIEFMVKEKGF----NEDRIKSGIERLRKGLKVGVQKRLDSFF 347
W P + L FM + G+ +++ + I + K K G QKR++ FF
Sbjct: 948 TPFVWGVPDLDMLRSFMKTQLGWPHEKSDEILIPLIRDVNKRKKKGKQKRINEFF 1002
Score = 65.1 bits (157), Expect = 2e-10
Identities = 33/90 (36%), Positives = 52/90 (57%), Gaps = 6/90 (6%)
Query: 29 RKVAIDASMSLYQFLIAVRQQDGVQLAGEDGETTSHLMGMFYRTLRMIDHGIKPCYVFDG 88
+++A+DAS+ +YQFL AVR Q+G + SH+ G F R +++ GI+P +VFDG
Sbjct: 25 KRMAVDASIWIYQFLKAVRDQEG------NAVKNSHITGFFRRICKLLYFGIRPVFVFDG 78
Query: 89 SPPELKKYELDKRKVRREDTEAKLKEATEQ 118
P LK+ + +RK RR+ K +
Sbjct: 79 GVPVLKRETIRQRKERRQGKRESAKSTARK 108
>7295491 [L] KOG2519 5'-3' exonuclease
Length = 726
Score = 87.8 bits (216), Expect = 2e-17
Identities = 75/273 (27%), Positives = 123/273 (44%), Gaps = 39/273 (14%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDA------SMSLYQFLIAVRQQDGVQL 54
MG+K L +++ + + I G+KVAID S+++ + + R
Sbjct: 1 MGVKELWGVLTPHC----ERKPINELRGKKVAIDLAGWVCESLNVVDYFVHPRH------ 50
Query: 55 AGEDGETTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKR-KVRREDTEAKLK 113
HL +F+RT +I + P +V +G P+LK + KR +++ + K
Sbjct: 51 ---------HLKNLFFRTCYLIWEQVTPVFVLEGVAPKLKSQVIAKRNELQFRGVKPKNS 101
Query: 114 EATEQAEIIKHER---RLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKV 170
Q++ K ++ R VL ++ + LL MGI V P EAEA CA L K G V
Sbjct: 102 PECTQSQPSKGDKGRSRFNHVL----KQCETLLLSMGIQCVQGPGEAEAYCAFLNKHGLV 157
Query: 171 FAAASEDMDTLCYQTPVLLRHLTFS-----EARKLPIQEFDTDVIYNTLDLTQTQFIDLG 225
S+D D Y + R+ + S A + +D I + +D Q + I +
Sbjct: 158 DGVISQDSDCFAYGAVRVYRNFSVSTQGAQAAAGGAVDIYDMREITSRMDFGQQKIIVMA 217
Query: 226 IILGCDYC-EGIKGVGPVNALKLIKEHGSLEAI 257
++ GCDYC +GI G+G LKL ++ E +
Sbjct: 218 LLCGCDYCPDGIGGIGKDGVLKLFNKYKETEIL 250
>Hs4503601 [L] KOG2520 5'-3' exonuclease
Length = 1186
Score = 85.1 bits (209), Expect = 2e-16
Identities = 80/301 (26%), Positives = 134/301 (43%), Gaps = 36/301 (11%)
Query: 87 DGSPPELKKYELDK----RKVRREDTEAKLKEATEQAEIIK-----HERRLVKVLPWHNE 137
DG P E +K D + + E+ E Q +K ER V
Sbjct: 711 DGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFL 770
Query: 138 EAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASEDMDTLCYQTPVLLRHLTFSEA 197
E+Q+LL L GIPY+ AP EAEAQCA L + + ++D D + + R+ F
Sbjct: 771 ESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRN--FFNK 828
Query: 198 RKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGIKGVGPVNALKLIKE---HGSL 254
K ++ + +N L L + + I+L +LG DY EGI VG V A++++ E HG L
Sbjct: 829 NKF-VEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHG-L 886
Query: 255 EAIV-------EKFENGDISSG-----------RWKIPEGWQFKEARDLFMQPDVIPSEE 296
E ++ E +N I ++ G+ + +++P V+ +
Sbjct: 887 EPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKP-VVDDSK 945
Query: 297 VTLKWEEPKAEELIEFMVKEKGFNEDRIKSGIERLRKGLKV-GVQKRLDSFFKIQPKTKE 355
+ W +P +++ EF + G+N + + + K L Q R+DSFF++ + KE
Sbjct: 946 GSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKE 1005
Query: 356 E 356
+
Sbjct: 1006 D 1006
Score = 54.3 bits (129), Expect = 3e-07
Identities = 39/136 (28%), Positives = 70/136 (50%), Gaps = 12/136 (8%)
Query: 28 GRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGETTSHLMGMFYRTLRMIDHGIKPCYVFD 87
G+ +A+D S+ L Q L VR + G + HL+ +F+R +++ I+P +VFD
Sbjct: 24 GKILAVDISIWLNQALKGVRDRHGNSIENP------HLLTLFHRLCKLLFFRIRPIFVFD 77
Query: 88 GSPPELKKYELDKRKVRREDTEAKLKEATEQAEIIKHERRLVKVLPWHNEEAQKLLSLMG 147
G P LKK L KR+ R++ + ++ TE+ +R+ +K + ++ + L SL
Sbjct: 78 GDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKT-AFRSKRDEALPSLTQ 136
Query: 148 IP-----YVVAPAEAE 158
+ YV+ P + E
Sbjct: 137 VRRENDLYVLPPLQEE 152
>YDR263c [L] KOG2518 5'-3' exonuclease
Length = 430
Score = 84.0 bits (206), Expect = 3e-16
Identities = 60/208 (28%), Positives = 102/208 (48%), Gaps = 8/208 (3%)
Query: 62 TSHLMGMFYRTLRMIDH-GIKPCYVFDGSPPELKKYELDKRKVRREDTEA---KLKEATE 117
T+ + F + L+++ IKP VFDG +K + +R+ +R + E KL A
Sbjct: 52 TNKYLQFFIKRLQLLKRLKIKPYIVFDGDSLFVKNHTETRRRKKRLENEMIAKKLWSAGN 111
Query: 118 QAEIIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASED 177
+ +++ ++ V + P + L IPY+VAP EA+ Q L K G + SED
Sbjct: 112 RYNAMEYFQKSVDITPEMAKCIIDYCKLHSIPYIVAPFEADPQMVYLEKMGLIQGIISED 171
Query: 178 MDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTL---DLTQTQFIDLGIILGCDYCE 234
D L + L+ L + + L I + D + +L++ QF +L + GCDY
Sbjct: 172 SDLLVFGCKTLITKLN-DQGKALEISKDDFSALPENFPLGELSEQQFRNLVCLAGCDYTS 230
Query: 235 GIKGVGPVNALKLIKEHGSLEAIVEKFE 262
GI VG V A+K++K + ++ I+ + E
Sbjct: 231 GIWKVGVVTAMKIVKRYSEMKDILIQIE 258
>Hs18491020 [L] KOG2518 5'-3' exonuclease
Length = 846
Score = 82.8 bits (203), Expect = 8e-16
Identities = 74/255 (29%), Positives = 122/255 (47%), Gaps = 18/255 (7%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGI+ L I E A + ++ + G+ VA+D L++ IA ++ LA GE
Sbjct: 1 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEK----LA--KGE 50
Query: 61 TTSHLMGMFYRTLRMI-DHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQA 119
T +G + + M+ HGIKP VFDG KK R+ RR+ K K+ +
Sbjct: 51 PTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREG 110
Query: 120 EIIKHERRLVKVLPWHNEEAQKLLSL---MGIPYVVAPAEAEAQCAELAKSGKVFAAASE 176
++ + + + + A K++ G+ +VAP EA+AQ A L K+G V A +E
Sbjct: 111 KVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE 170
Query: 177 DMDTLCYQ-TPVLLRHLTFSEARKLPIQEFDTDVIYNTLDL-TQTQFIDLGIILGCDYCE 234
D D L + V+L+ F L I + + D+ T+ +F + I+ GCDY
Sbjct: 171 DSDLLAFGCKKVILKMDQFGNG--LEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLS 228
Query: 235 GIKGVGPVNALKLIK 249
++G+G A K+++
Sbjct: 229 SLRGIGLAKACKVLR 243
>Hs18491018 [L] KOG2518 5'-3' exonuclease
Length = 803
Score = 82.8 bits (203), Expect = 8e-16
Identities = 74/255 (29%), Positives = 122/255 (47%), Gaps = 18/255 (7%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGI+ L I E A + ++ + G+ VA+D L++ IA ++ LA GE
Sbjct: 1 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEK----LA--KGE 50
Query: 61 TTSHLMGMFYRTLRMI-DHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQA 119
T +G + + M+ HGIKP VFDG KK R+ RR+ K K+ +
Sbjct: 51 PTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREG 110
Query: 120 EIIKHERRLVKVLPWHNEEAQKLLSL---MGIPYVVAPAEAEAQCAELAKSGKVFAAASE 176
++ + + + + A K++ G+ +VAP EA+AQ A L K+G V A +E
Sbjct: 111 KVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE 170
Query: 177 DMDTLCYQ-TPVLLRHLTFSEARKLPIQEFDTDVIYNTLDL-TQTQFIDLGIILGCDYCE 234
D D L + V+L+ F L I + + D+ T+ +F + I+ GCDY
Sbjct: 171 DSDLLAFGCKKVILKMDQFGNG--LEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLS 228
Query: 235 GIKGVGPVNALKLIK 249
++G+G A K+++
Sbjct: 229 SLRGIGLAKACKVLR 243
>Hs18491016 [L] KOG2518 5'-3' exonuclease
Length = 846
Score = 82.8 bits (203), Expect = 8e-16
Identities = 74/255 (29%), Positives = 122/255 (47%), Gaps = 18/255 (7%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGI+ L I E A + ++ + G+ VA+D L++ IA ++ LA GE
Sbjct: 1 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEK----LA--KGE 50
Query: 61 TTSHLMGMFYRTLRMI-DHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQA 119
T +G + + M+ HGIKP VFDG KK R+ RR+ K K+ +
Sbjct: 51 PTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREG 110
Query: 120 EIIKHERRLVKVLPWHNEEAQKLLSL---MGIPYVVAPAEAEAQCAELAKSGKVFAAASE 176
++ + + + + A K++ G+ +VAP EA+AQ A L K+G V A +E
Sbjct: 111 KVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE 170
Query: 177 DMDTLCYQ-TPVLLRHLTFSEARKLPIQEFDTDVIYNTLDL-TQTQFIDLGIILGCDYCE 234
D D L + V+L+ F L I + + D+ T+ +F + I+ GCDY
Sbjct: 171 DSDLLAFGCKKVILKMDQFGNG--LEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLS 228
Query: 235 GIKGVGPVNALKLIK 249
++G+G A K+++
Sbjct: 229 SLRGIGLAKACKVLR 243
>SPBC29A10.05 [L] KOG2518 5'-3' exonuclease
Length = 571
Score = 82.4 bits (202), Expect = 1e-15
Identities = 75/268 (27%), Positives = 122/268 (44%), Gaps = 26/268 (9%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGIK L L+ KS ++ F G+ + +D + L++ + + + E
Sbjct: 1 MGIKGLLGLLKPMQ----KSSHVEEFSGKTLGVDGYVWLHKAVFTCAHE-----LAFNKE 51
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDT---EAKLKEATE 117
T +L ++ L + +G+KP VFDG P K KRK RR++ KL + +
Sbjct: 52 TDKYLKYAIHQALMLQYYGVKPLIVFDGGPLPCKASTEQKRKERRQEAFELGKKLWDEGK 111
Query: 118 QAEIIKHERRLVKVLPWHNEEAQKLLSLM---GIPYVVAPAEAEAQCAELAKSGKVFAAA 174
+++ I R V V P E A KL+ + GI +VAP EA+AQ L K +
Sbjct: 112 KSQAIMQFSRCVDVTP---EMAWKLIIALREHGIESIVAPYEADAQLVYLEKENIIDGII 168
Query: 175 SEDMDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFID----LGIILGC 230
+ED D L + +L + + I+ D I N DL I+ + I GC
Sbjct: 169 TEDSDMLVFGAQTVLFKMD-GFGNCITIRRND---IANAQDLNLRLPIEKLRHMAIFSGC 224
Query: 231 DYCEGIKGVGPVNALKLIKEHGSLEAIV 258
DY +G+ G+G AL+ ++++ A +
Sbjct: 225 DYTDGVAGMGLKTALRYLQKYPEPRAAI 252
>SPBC3E7.08c [L] KOG2520 5'-3' exonuclease
Length = 1112
Score = 81.3 bits (199), Expect = 2e-15
Identities = 70/269 (26%), Positives = 124/269 (46%), Gaps = 31/269 (11%)
Query: 105 REDTEAKLKEATEQAEIIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAEL 164
+E E +LKE Q +R +V +E Q+LL L G+PY+VAP EAEAQC++L
Sbjct: 728 QEAFEKRLKELKNQKR--SEKRDADEVTQVMIKECQELLRLFGLPYIVAPQEAEAQCSKL 785
Query: 165 AKSGKVFAAASEDMDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDL 224
+ V ++D D + + R++ F++ + ++ + D + ++ Q I L
Sbjct: 786 LELKLVDGIVTDDSDVFLFGGTRVYRNM-FNQNKF--VELYLMDDMKREFNVNQMDLIKL 842
Query: 225 GIILGCDYCEGIKGVGPVNALKLIKEHGSLEAIVE------KFENGDISS---------- 268
+LG DY G+ VGPV AL+++ E + E + G S
Sbjct: 843 AHLLGSDYTMGLSRVGPVLALEILHEFPGDTGLFEFKKWFQRLSTGHASKNDVNTPVKKR 902
Query: 269 -----GRWKIPEGWQFKEARDLFMQPDVIPSEEVTLKWEEPKAEELIEFMVKEKGFNEDR 323
G+ +P + + ++ P V S++ + +W P +EL +F++ G+++ R
Sbjct: 903 INKLVGKIILPSEFPNPLVDEAYLHPAVDDSKQ-SFQWGIPDLDELRQFLMATVGWSKQR 961
Query: 324 ----IKSGIERLRKGLKVGVQKRLDSFFK 348
+ I+ + K VG Q L FF+
Sbjct: 962 TNEVLLPVIQDMHKKQFVGTQSNLTQFFE 990
Score = 74.3 bits (181), Expect = 3e-13
Identities = 43/109 (39%), Positives = 66/109 (60%), Gaps = 10/109 (9%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MG+ L ++ E V +K ++ +++AIDAS+ +YQFL AVR ++G QL
Sbjct: 1 MGVSGLWDIL-EPVKRPVK---LETLVNKRLAIDASIWIYQFLKAVRDKEGNQLK----- 51
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTE 109
+SH++G F R +++ GIKP +VFDG P LK+ + KR+ RR D E
Sbjct: 52 -SSHVVGFFRRICKLLFFGIKPVFVFDGGAPSLKRQTIQKRQARRLDRE 99
>ECU11g0760 [L] KOG2518 5'-3' exonuclease
Length = 366
Score = 79.3 bits (194), Expect = 9e-15
Identities = 64/264 (24%), Positives = 126/264 (47%), Gaps = 20/264 (7%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGI L +++ P +K + I + ++V +D LYQ L V ++ ++
Sbjct: 1 MGISGLLPIVA---PKLVK-KHISSYKRQRVGVDGHAWLYQILPCVAEEMFFKVP----- 51
Query: 61 TTSHLMGMFYRTLRMID-HGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKE---AT 116
T + +F +++++ +GI P V DG K+ KR++R+E + + +
Sbjct: 52 -TKRHVDLFEEKVKLLESYGIIPVIVLDGDLLSSKEETNRKRRIRKEKSRKEAEYWLMRN 110
Query: 117 EQAEIIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASE 176
+ A+ R+ + V + ++L + + Y+++P E++AQ L + G + +E
Sbjct: 111 DPAKAKGFMRQCIAVTREVVSDIARMLERINVEYIISPYESDAQLCFLQRIGYIDCILTE 170
Query: 177 DMDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLT-QTQFIDLGIILGCDYCEG 235
D D + Y + +L F A +QEF+ + + + +D+ I+ GCDY
Sbjct: 171 DSDLIPYGSSKVL--YKFDSAF---VQEFNRECLSEVKGKDFEENILDISILSGCDYLAS 225
Query: 236 IKGVGPVNALKLIKEHGSLEAIVE 259
I+GVG V A +L+ ++E +VE
Sbjct: 226 IQGVGVVTAHRLLSREKTVERVVE 249
>At1g29630 [L] KOG2518 5'-3' exonuclease
Length = 317
Score = 77.0 bits (188), Expect = 4e-14
Identities = 87/333 (26%), Positives = 144/333 (43%), Gaps = 40/333 (12%)
Query: 1 MGIKNLATLI-SEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDG 59
MGI+ L L+ S VP IK + G VA+D L++ ++ ++ L
Sbjct: 1 MGIQGLLPLLKSIMVPIHIKELE-----GCIVAVDTYSWLHKGALSCSRELCKGLP---- 51
Query: 60 ETTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKR-KVRREDTEAKLKEATEQ 118
T H+ +R + HG+KP VFDG P +K + +KR + R+E+ L+
Sbjct: 52 -TKRHIQYCMHRVNLLRHHGVKPIMVFDGGPLPMKLEQENKRARSRKENLARALEHEANG 110
Query: 119 AEIIKHE--RRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASE 176
+E + V + P E ++L + YVVAP EA+AQ A LA + +V A +E
Sbjct: 111 NSSAAYECYSKAVDISPSIAHELIQVLRQENVDYVVAPYEADAQMAFLAITKQVDAIITE 170
Query: 177 DMDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQF-----IDLGIILGCD 231
D D + P + F + EF + DL+ + F +++ I+ GCD
Sbjct: 171 DSDLI----PFGCLRIIFKMDKFGHGVEFQASKLPKNKDLSLSGFSSQMLLEMCILSGCD 226
Query: 232 YCEGIKGVGPVNALKLIKEHGSLEAIVEKFENGDISSGRWKIPEGWQ--FKEARDLFMQP 289
Y + + G+G A LI + S + +++ + +S +P ++ FK A F
Sbjct: 227 YLQSLPGMGLKRAHALITKFKSYDRVIKHLKYSTVS-----VPPLYEESFKRALLTFKHQ 281
Query: 290 DVIPSEEVTLKWEEPKAEELIEFMVKEKGFNED 322
V +P AE++I ED
Sbjct: 282 RVY----------DPNAEDIIHLCDISDNLGED 304
>SPAC12G12.16c [L] KOG2519 5'-3' exonuclease
Length = 496
Score = 75.5 bits (184), Expect = 1e-13
Identities = 46/139 (33%), Positives = 77/139 (55%), Gaps = 2/139 (1%)
Query: 117 EQAEIIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAP--AEAEAQCAELAKSGKVFAAA 174
+Q E+ K ERRL + P + E ++L ++GIP +P EAEA + ++++ +A A
Sbjct: 259 KQTELDKLERRLYRPSPQNIFEIFEILKILGIPASFSPIGVEAEAFASAISQNNLAYAVA 318
Query: 175 SEDMDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCE 234
++D D L + ++ L ++ LP+Q D I L+LT F D ++ G D+
Sbjct: 319 TQDTDVLLLGSSMISNFLDLNDNFHLPLQIMDPRKIAQELNLTFDGFQDYCLMCGTDFTS 378
Query: 235 GIKGVGPVNALKLIKEHGS 253
I +GPV ALKLI+ +G+
Sbjct: 379 RIPKIGPVRALKLIRYYGN 397
>At3g28030 [L] KOG2520 5'-3' exonuclease
Length = 1482
Score = 75.5 bits (184), Expect = 1e-13
Identities = 50/146 (34%), Positives = 77/146 (52%), Gaps = 6/146 (4%)
Query: 123 KHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASEDMDTLC 182
K ER V E Q+LL + GIPY++AP EAEAQCA + +S V ++D D
Sbjct: 913 KLERNAESVSSEMFAECQELLQIFGIPYIIAPMEAEAQCAFMEQSNLVDGIVTDDSDVFL 972
Query: 183 YQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGIKGVGPV 242
+ + +++ + RK F D I L L++ + I + ++LG DY EGI G+G V
Sbjct: 973 FGARSVYKNI--FDDRKYVETYFMKD-IEKELGLSRDKIIRMAMLLGSDYTEGISGIGIV 1029
Query: 243 NALKLI---KEHGSLEAIVEKFENGD 265
NA++++ E L+ E E+ D
Sbjct: 1030 NAIEVVTAFPEEDGLQKFREWVESPD 1055
Score = 58.9 bits (141), Expect = 1e-08
Identities = 30/90 (33%), Positives = 55/90 (60%), Gaps = 6/90 (6%)
Query: 29 RKVAIDASMSLYQFLIAVRQQDGVQLAGEDGETTSHLMGMFYRTLRMIDHGIKPCYVFDG 88
+++AIDAS+ + QF+ A+R + G D +HL+G F R +++ KP +VFDG
Sbjct: 25 KRLAIDASIWMVQFIKAMRDEKG------DMVQNAHLIGFFRRICKLLFLRTKPIFVFDG 78
Query: 89 SPPELKKYELDKRKVRREDTEAKLKEATEQ 118
+ P LK+ + R+ +RE+ + K+++ E+
Sbjct: 79 ATPALKRRTVIARRRQRENAQTKIRKTAEK 108
>7297419 [L] KOG2520 5'-3' exonuclease
Length = 1236
Score = 73.9 bits (180), Expect = 4e-13
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 7/192 (3%)
Query: 98 LDKRKVRREDTEAKLKEATEQAEII----KHERRLVKVLPWHNEEAQKLLSLMGIPYVVA 153
L +K E E A E+ E+ + +R + + + + Q+LL L GIPY+VA
Sbjct: 818 LKSQKTSEELQELATNLAQERKELEIERNRQDRMGMSISQRMSIDCQELLRLFGIPYIVA 877
Query: 154 PAEAEAQCAELAKSGKVFAAASEDMDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNT 213
P EAEAQCA L + ++D D + + ++ A+ + EF + I T
Sbjct: 878 PMEAEAQCAFLNATDLTHGTITDDSDIWLFGGRTVYKNFF---AQNKHVMEFRAEQIEQT 934
Query: 214 LDLTQTQFIDLGIILGCDYCEGIKGVGPVNALKLIKEHGSLEAIVEKFENGDISSGRWKI 273
+ + + I L ++G DY GI G+G V AL+++ +A N + K
Sbjct: 935 FNCNRGKLIQLACLVGSDYTTGIHGIGAVTALEILASFSGQDANGPGICNQSVLQTLIKF 994
Query: 274 PEGWQFKEARDL 285
+ WQ + +L
Sbjct: 995 RDWWQAHKCSNL 1006
Score = 50.1 bits (118), Expect = 6e-06
Identities = 28/105 (26%), Positives = 57/105 (53%), Gaps = 10/105 (9%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MG+ L LI K ++ G+ +A+D S+ L+Q + + G L+
Sbjct: 1 MGVTGLWKLIEP----CGKPVPVETLEGKILAVDISIWLHQVVKGFQDNKGSALSN---- 52
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRR 105
+HL+G+F+R +++ + ++P ++FDG P+LK+ + +R+ +R
Sbjct: 53 --AHLLGLFHRLCKLLYYRVRPVFIFDGCVPQLKRDTIARRQQQR 95
>YOR033c [L] KOG2518 5'-3' exonuclease
Length = 702
Score = 73.6 bits (179), Expect = 5e-13
Identities = 71/281 (25%), Positives = 126/281 (44%), Gaps = 20/281 (7%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGI+ L + + + N + ++ + G +AID Y +L +LA G+
Sbjct: 1 MGIQGLLPQL-KPIQNPVS---LRRYEGEVLAIDG----YAWLHRAACSCAYELAM--GK 50
Query: 61 TTSHLMGMFYRTLRMID-HGIKPCYVFDGSPPELKKYELDKRKVRREDTEA---KLKEAT 116
T + F + ++ ++P VFDG +KK KR+ +R++ +A +L
Sbjct: 51 PTDKYLQFFIKRFSLLKTFKVEPYLVFDGDAIPVKKSTESKRRDKRKENKAIAERLWACG 110
Query: 117 EQAEIIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASE 176
E+ + + ++ V + P + L GI Y+VAP EA++Q L + V SE
Sbjct: 111 EKKNAMDYFQKCVDITPEMAKCIICYCKLNGIRYIVAPFEADSQMVYLEQKNIVQGIISE 170
Query: 177 DMDTLCYQTPVLLRHLT-FSEARKLPIQEF-DTDVIYNTLDLTQTQFIDLGIILGCDYCE 234
D D L + L+ L + E ++ F + LT + I + + GCDY
Sbjct: 171 DSDLLVFGCRRLITKLNDYGECLEICRDNFIKLPKKFPLGSLTNEEIITMVCLSGCDYTN 230
Query: 235 GIKGVGPVNALKLIKEHGSLEAIVEKFENGDISSGRWKIPE 275
GI VG + A+KL++ ++E I+ + G+ IP+
Sbjct: 231 GIPKVGLITAMKLVRRFNTIERIILSIQR----EGKLMIPD 267
>At1g01880 [L] KOG2519 5'-3' exonuclease
Length = 570
Score = 71.2 bits (173), Expect = 2e-12
Identities = 63/247 (25%), Positives = 112/247 (44%), Gaps = 21/247 (8%)
Query: 25 YFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGETTSHLMGMFYRTLRMIDH-GIKPC 83
+ ++VA+D S + Q AV+ G L HL F+RT+ + G P
Sbjct: 22 FLRNKRVAVDLSFWIVQHETAVK---GFVLK-------PHLRLTFFRTINLFSKFGAYPV 71
Query: 84 YVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQAEIIKHERRLVKVLPWHNEEAQKLL 143
+V DG+P LK R R + + ++ + + + E +LL
Sbjct: 72 FVVDGTPSPLKSQARISRFFRSSGIDTCNLPVIKDGVSVERNKLFSEWV----RECVELL 127
Query: 144 SLMGIPYVVAPAEAEAQCAELAKSGKVFAAASEDMDTLCYQTPVLLRHLTFSEARKLPIQ 203
L+GIP + A EAEA CA+L G V A + D D + +++ + + P +
Sbjct: 128 ELLGIPVLKANGEAEALCAQLNSQGFVDACITPDSDAFLFGAMCVIKDI--KPNSREPFE 185
Query: 204 EFDTDVIYNTLDLTQTQFIDLGIILGCDY-CEGIKGVGPVNALKLIKEHGSLEAIVEKFE 262
+ I + L L + I + +++G DY G+ G+G AL++++E S + ++E+ +
Sbjct: 186 CYHMSHIESGLGLKRKHLIAISLLVGNDYDSGGVLGIGVDKALRIVREF-SEDQVLERLQ 244
Query: 263 NGDISSG 269
DI +G
Sbjct: 245 --DIGNG 249
>ECU09g1620 [L] KOG2520 5'-3' exonuclease
Length = 562
Score = 69.7 bits (169), Expect = 7e-12
Identities = 40/111 (36%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Query: 140 QKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASEDMDTLCYQTPVLLRHLTFSEARK 199
+ +L + IPYV AP EA+ QC + + V +ED D L Y V F + R+
Sbjct: 393 KSVLEVFNIPYVDAPMEADGQCGFMCHNNVVDGVITEDNDVLLYGGTVYRNF--FRKDRE 450
Query: 200 LPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGIKGVGPVNALKLIKE 250
I+++ D I L L + I L +LG DY +G+KG+GPV AL+ I++
Sbjct: 451 --IEKYSLDRIERELQLDRKNLITLSYLLGSDYTDGVKGIGPVKALEAIRK 499
>CE11308 [L] KOG2520 5'-3' exonuclease
Length = 829
Score = 69.7 bits (169), Expect = 7e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 20/171 (11%)
Query: 98 LDKRKVRREDTEAKL------KEATEQAEIIKHERRLVKV------LPWHNEEAQKLLSL 145
L+K KV ED E + K +T A + + + P + Q+ L+
Sbjct: 428 LEKHKVPSEDEEIEWDPQRYDKPSTSSAPALMEDYIHLNYSDEDDKTPELYRDLQEFLTN 487
Query: 146 MGIPYVVAPAEAEAQCAELAKSGKVFAAASEDMDTLCYQTPVLLRHLTFSEARKLPIQEF 205
GIP++ +P EAEAQC EL + G V S+D D + + RH+ FS+ R+ +Q +
Sbjct: 488 AGIPWIESPGEAEAQCVELERLGLVDGVVSDDSDVWAFGAQHVYRHM-FSKNRR--VQRY 544
Query: 206 DTDVIYN-----TLDLTQTQFIDLGIILGCDYCEGIKGVGPVNALKLIKEH 251
N L + +I + ++ G DYC G+ VG + AL+L+ E+
Sbjct: 545 GEQTTANRDNCKLFCLQREDYISIALLSGGDYCAGLVKVGAIGALELVSEY 595
>At1g18090 [L] KOG2518 5'-3' exonuclease
Length = 534
Score = 63.2 bits (152), Expect = 6e-10
Identities = 69/282 (24%), Positives = 117/282 (41%), Gaps = 31/282 (10%)
Query: 58 DGETTSHLMGMFYRTLRMIDH-GIKPCYVFDGSPPELKKYELDKRKVRR----EDTEAKL 112
DG+ + F + ++ H I P V DG K D+R +R + KL
Sbjct: 8 DGKKKLRYIDYFMHRVNLLQHYEIIPVVVLDGGNMPCKAATGDERHRQRKANFDAAMVKL 67
Query: 113 KEATEQAEIIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELA----KSG 168
KE A +R V V + ++L + ++VAP EA+AQ A L+ + G
Sbjct: 68 KEGNVAAATELFQRA-VSVTSSMAHQLIQVLKSENVEFIVAPYEADAQLAYLSSLELEQG 126
Query: 169 KVFAAASEDMDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLD-------LTQTQF 221
+ A +ED D L Y ++ F R +E D ++ +D Q F
Sbjct: 127 GIAAVITEDSDLLAYGCKAVI----FKMDRYGKGEELVLDNVFQAVDQKPSFQNFDQELF 182
Query: 222 IDLGIILGCDYCEGIKGVGPVNALKLIKEHGSLEAIVE--KFENGDISSGRWKIPEGW-- 277
+ ++ GCD+ + GVG A I ++ S+E ++ K + G + +P+ +
Sbjct: 183 TAMCVLAGCDFLPSVPGVGISRAHAFISKYQSVELVLSFLKTKKGKL------VPDDYSS 236
Query: 278 QFKEARDLFMQPDVIPSEEVTLKWEEPKAEELIEFMVKEKGF 319
F EA +F V + LK +P + L+ V++ F
Sbjct: 237 SFTEAVSVFQHARVYDFDAKKLKHLKPLSHNLLNLPVEQLEF 278
>CE01401 [L] KOG2520 5'-3' exonuclease
Length = 434
Score = 61.6 bits (148), Expect = 2e-09
Identities = 62/261 (23%), Positives = 103/261 (38%), Gaps = 41/261 (15%)
Query: 2 GIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGET 61
GI A + +VPN + + ++ID + LY+ L A
Sbjct: 5 GIWEWANHVVRKVPN-------ETMRDKTLSIDGHIWLYESLKGCE-------AHHQQTP 50
Query: 62 TSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQAEI 121
S+L+ F R R+++ I P VFD + + E+ +Q E
Sbjct: 51 NSYLVTFFTRIQRLLELKIIPIVVFDNI-----------------NASSSAHESKDQNEF 93
Query: 122 IKHERRLVKVLPW-----HNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASE 176
+ +RR P+ H + LL+ +GI ++AP + EAQCA L G +
Sbjct: 94 VPRKRRSFGDSPFTNLVDHVYKTNALLTELGIKVIIAPGDGEAQCARLEDLGVTSGCITT 153
Query: 177 DMDTLCYQTPVLLRH----LTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDY 232
D D + L R T S A I ++ +++ I I+LGCDY
Sbjct: 154 DFDYFLFGGKNLYRFDFTAGTSSTACLHDIMHLSLGRMFMEKKVSRPHLISTAILLGCDY 213
Query: 233 CE-GIKGVGPVNALKLIKEHG 252
+ G++ +G V+ ++ E G
Sbjct: 214 FQRGVQNIGIVSVFDILGEFG 234
>7298467 [L] KOG2518 5'-3' exonuclease
Length = 732
Score = 54.7 bits (130), Expect = 2e-07
Identities = 64/260 (24%), Positives = 108/260 (40%), Gaps = 29/260 (11%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGI L + + A +K G VA+D L++ + ++ GED
Sbjct: 1 MGITGLIPFVGK----ASSQLHLKDIRGSTVAVDTYCWLHKGVFGCAEK---LARGED-- 51
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQAE 120
T ++ ++ + IKP VFDG K +R+ R+ ++ + E
Sbjct: 52 TDVYIQYCLKYVNMLLSYDIKPILVFDGQHLPAKALTEKRRRDSRKQSKERAAELLRLGR 111
Query: 121 IIK---HERRLVKVLPWHNEEAQKLLS---LMGIPYVVAPAEAEAQCAELAKSGKVFAAA 174
I + H RR V V ++ A +L+ + +VAP EA+AQ A L ++
Sbjct: 112 IEEARSHMRRCVDVT---HDMALRLIRECRSRNVDCIVAPYEADAQMAWLNRADVAQYII 168
Query: 175 SEDMDTLCYQTPVLLRHLTFS------EARKLPIQEFDTDVIYNTLDLTQTQFIDLGIIL 228
+ED D + ++ L + EA KL + T+ Y+ +F + I+
Sbjct: 169 TEDSDLTLFGAKNIIFKLDLNGSGLLVEAEKLHLAMGCTEEKYHF-----DKFRRMCILS 223
Query: 229 GCDYCEGIKGVGPVNALKLI 248
GCDY + + G+G A K I
Sbjct: 224 GCDYLDSLPGIGLAKACKFI 243
>CE28728 [L] KOG2518 5'-3' exonuclease
Length = 639
Score = 53.9 bits (128), Expect = 4e-07
Identities = 71/262 (27%), Positives = 112/262 (42%), Gaps = 32/262 (12%)
Query: 1 MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGE 60
MGI L + NA + +I G+ VAID S L++ L D + + GE+ +
Sbjct: 1 MGISGLLPFVK----NACRKGNILELRGKSVAIDVSCLLHRGLTGC--MDKIHM-GEETQ 53
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQ-- 118
+ + + + + L + G VFDG P KK ++R+ RE K KE E
Sbjct: 54 SYVNYVNKYVKEL--LGMGCHVVMVFDGRPLPAKKGTNEERRELRE----KRKEHAEMLL 107
Query: 119 AEIIKHERRLVKVLPWH------NEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFA 172
A+ ++ E R L Q S+ + VVAP EA+AQ A L + V A
Sbjct: 108 AKGLEREARDTYRLATSISADIVENTIQYFRSMTNVDIVVAPYEADAQLAYLVQEKLVDA 167
Query: 173 AASEDMDTLCYQTPVLLRHLTFSEARKLPIQE-------FDTDVIYNTLDLTQTQFIDLG 225
+ED D + + ++ S + + E F ++ + D +F +
Sbjct: 168 VITEDSDLIVFGCEMIYFKWQ-SATGECSVYEKCNLKNCFTGELGGDKFDF--VKFRRIC 224
Query: 226 IILGCDYCE-GIKGVGPVNALK 246
I+ GCDY + G+ GVG A K
Sbjct: 225 ILSGCDYLQAGLPGVGLSTAAK 246
>YER041w [L] KOG2520 5'-3' exonuclease
Length = 759
Score = 52.4 bits (124), Expect = 1e-06
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 28/214 (13%)
Query: 61 TTSHLMGMFYRTLRMIDHGIKPCYVFDG-SPPELKKYELDKRKVRREDTEAKLKEATEQA 119
T ++ R ++ ++ VFDG P K+ ++ D E + + EQ
Sbjct: 92 TGKAVINFISRLKELLSLNVEFLLVFDGVMKPSFKRKFNHEQNATTCDDEKEYYSSWEQ- 150
Query: 120 EIIKHE------RRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAA 173
+ HE L P +KLL LM I YV+A E EAQC L SG V
Sbjct: 151 HVKNHEVYGNCKGLLAPSDPEFISLVRKLLDLMNISYVIACGEGEAQCVWLQVSGAVDFI 210
Query: 174 ASEDMDTLCYQTPVLLRHLT--------FSEARKLPIQEFDTDVIYNT-LDL-------- 216
S D DTL + +L++ + S P + D+ + T +DL
Sbjct: 211 LSNDSDTLVFGGEKILKNYSKFYDDFGPSSITSHSPSRHHDSKESFVTVIDLPKINKVAG 270
Query: 217 ---TQTQFIDLGIILGCDYCEGIKGVGPVNALKL 247
+ + ++LG DY G+KG+G +L+L
Sbjct: 271 KKFDRLSLLFFSVLLGADYNRGVKGLGKNKSLQL 304
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,247,216
Number of Sequences: 60738
Number of extensions: 930540
Number of successful extensions: 3225
Number of sequences better than 1.0e-05: 30
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 3151
Number of HSP's gapped (non-prelim): 37
length of query: 381
length of database: 30,389,216
effective HSP length: 108
effective length of query: 273
effective length of database: 23,829,512
effective search space: 6505456776
effective search space used: 6505456776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)