ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0878 good R KOG0370 General function prediction only Multifunctional pyrimidine synthesis protein CAD (includes carbamoyl-phophate synthetase, aspartate transcarbamylase, and glutamine amidotransferase)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0878 300236 296886 -1117
(1117 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR109c [R] KOG0370 Multifunctional pyrimidine synthesis protein... 1771 0.0
SPBC215.08c [R] KOG0370 Multifunctional pyrimidine synthesis pro... 1399 0.0
YJL130c [R] KOG0370 Multifunctional pyrimidine synthesis protein... 1096 0.0
Hs18105007 [R] KOG0370 Multifunctional pyrimidine synthesis prot... 1077 0.0
7293258 [R] KOG0370 Multifunctional pyrimidine synthesis protein... 1061 0.0
SPAC22G7.06c [R] KOG0370 Multifunctional pyrimidine synthesis pr... 1061 0.0
CE03105 [R] KOG0370 Multifunctional pyrimidine synthesis protein... 1031 0.0
Hs21361331 [R] KOG0370 Multifunctional pyrimidine synthesis prot... 1014 0.0
HsM4503019 [R] KOG0370 Multifunctional pyrimidine synthesis prot... 994 0.0
At1g29900 [R] KOG0370 Multifunctional pyrimidine synthesis prote... 324 4e-88
7303838 [C] KOG0369 Pyruvate carboxylase 64 2e-09
CE09072 [C] KOG0369 Pyruvate carboxylase 63 2e-09
Hs13518228 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-... 62 7e-09
YGL062w [C] KOG0369 Pyruvate carboxylase 60 3e-08
YMR207c [I] KOG0368 Acetyl-CoA carboxylase 59 6e-08
YBR208c_2 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-c... 59 6e-08
YBR218c [C] KOG0369 Pyruvate carboxylase 56 3e-07
Hs4826637 [I] KOG0368 Acetyl-CoA carboxylase 55 5e-07
Hs4505627 [C] KOG0369 Pyruvate carboxylase 55 6e-07
7302098 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-con... 55 6e-07
SPBC17G9.11c [C] KOG0369 Pyruvate carboxylase 54 1e-06
At1g36180 [I] KOG0368 Acetyl-CoA carboxylase 54 2e-06
7304119 [I] KOG0368 Acetyl-CoA carboxylase 54 2e-06
At5g35360 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-c... 53 2e-06
SPAC56E4.04c [I] KOG0368 Acetyl-CoA carboxylase 52 4e-06
Hs4557833 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-c... 52 4e-06
At1g36160 [I] KOG0368 Acetyl-CoA carboxylase 52 4e-06
Hs4501855 [I] KOG0368 Acetyl-CoA carboxylase 52 7e-06
CE09857 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-con... 52 7e-06
YNR016c [I] KOG0368 Acetyl-CoA carboxylase 51 9e-06
>YJR109c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1118
Score = 1771 bits (4587), Expect = 0.0
Identities = 896/1118 (80%), Positives = 986/1118 (88%), Gaps = 8/1118 (0%)
Query: 3 TSIYSSTEPTTSAFNTDEYNPQLVEGVESVLVIGSGGLSIGQAGEFDYSGSQAIKALKEA 62
TSIY+STEPT SAF T++Y PQLVEGV SVLVIGSGGLSIGQAGEFDYSGSQAIKALKE
Sbjct: 2 TSIYTSTEPTNSAFTTEDYKPQLVEGVNSVLVIGSGGLSIGQAGEFDYSGSQAIKALKED 61
Query: 63 NKKTILVNPNIATNQTSHSLADEIYYLPVTPEYITYIIERERPDAILLTFGGQTGLNCGV 122
NK TILVNPNIATNQTSHSLAD+IYYLPVTPEYITYIIE ERPDAILLTFGGQTGLNCGV
Sbjct: 62 NKFTILVNPNIATNQTSHSLADKIYYLPVTPEYITYIIELERPDAILLTFGGQTGLNCGV 121
Query: 123 ALDKAGVLAKYNIKVLGTPIKTLETSEDRDLFAQALKEIDIPTAESIACETVDAALEAAD 182
ALD++GVLAKYN+KVLGTPIKTL TSEDRDLFA ALK+I+IP AES ACETVD ALEAA+
Sbjct: 122 ALDESGVLAKYNVKVLGTPIKTLITSEDRDLFASALKDINIPIAESFACETVDEALEAAE 181
Query: 183 IVGFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLAPQILVEKSLKGWKEVEYEVVR 242
V +PVIVRSAYALGGLGSGFANNA EMK+LA+QSLSLAPQILVEKSLKGWKEVEYEVVR
Sbjct: 182 RVKYPVIVRSAYALGGLGSGFANNASEMKELAAQSLSLAPQILVEKSLKGWKEVEYEVVR 241
Query: 243 DRVGNCITVCNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECN 302
DRVGNCITVCNMENFDPLG+HTGDS+VFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECN
Sbjct: 242 DRVGNCITVCNMENFDPLGVHTGDSMVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECN 301
Query: 303 VQYALSPDSLDYRVIEVNXXXXXXXXXXXXXTGYPLAYTAAKIALGYTLPELPNPITKTT 362
VQYAL PD LDYRVIEVN TGYPLAYTAAKI LGYTLPELPNPITKTT
Sbjct: 302 VQYALQPDGLDYRVIEVNARLSRSSALASKATGYPLAYTAAKIGLGYTLPELPNPITKTT 361
Query: 363 VANFEPSLDYIVAKIPRWDLSKFQHVNRSVGSSMKSVGEVMAIGRNFEEAFQKAIRQIDP 422
VANFEPSLDYIVAKIP+WDLSKFQ+V+RS+GSSMKSVGEVMAIGRN+EEAFQKA+RQ+DP
Sbjct: 362 VANFEPSLDYIVAKIPKWDLSKFQYVDRSIGSSMKSVGEVMAIGRNYEEAFQKALRQVDP 421
Query: 423 SFIGFQGSDEF-DDLDNALSEPTDRRWLAVGQALIHEGYSVEKVHELTKIDSWFLFKCMN 481
S +GFQGS EF D LD AL PTDRR LA+GQALIHE Y+VE+V+EL+KID WFL+KCMN
Sbjct: 422 SLLGFQGSTEFGDQLDEALRTPTDRRVLAIGQALIHENYTVERVNELSKIDKWFLYKCMN 481
Query: 482 IVDMYKDLEQVNDXXXXXXXXXXXXXXXGFSDAQIALCLNKGSDSRTSELEVRSYRKSFG 541
IV++YK+LE V GFSD QIA+ +NK + + +ELE+RS RK+ G
Sbjct: 482 IVNIYKELESVKSLSDLSKDLLQRAKKLGFSDKQIAVTINKHASTNINELEIRSLRKTLG 541
Query: 542 IVPFVKRIDTLAAEFPAQTNYLYTTYNATKSDIEFTDNGVLVLGSGVYRIGSSVEFDWCA 601
I+PFVKRIDTLAAEFPAQTNYLYTTYNATK+D+EF +NG+LVLGSGVYRIGSSVEFDWCA
Sbjct: 542 IIPFVKRIDTLAAEFPAQTNYLYTTYNATKNDVEFNENGMLVLGSGVYRIGSSVEFDWCA 601
Query: 602 VNTTKALRKEGKKTIMINYNPETVSTDFDEVDRLYFEELSFERVMDIYELENSEGCVISV 661
VNT K LR +GKKTIMINYNPETVSTDFDEVDRLYFEELS+ERVMDIYELE SEGC+ISV
Sbjct: 602 VNTAKTLRDQGKKTIMINYNPETVSTDFDEVDRLYFEELSYERVMDIYELEQSEGCIISV 661
Query: 662 GGQLPQNIALKLLHNGAHILGTSPEDIDKAENRHKFSTILDSIGVNQPEWSELSSVEEAK 721
GGQLPQNIALKL NG +I+GT+P DID+AENRHKFS+ILDSI V+QPEWSEL+SVEEAK
Sbjct: 662 GGQLPQNIALKLYDNGCNIMGTNPNDIDRAENRHKFSSILDSIDVDQPEWSELTSVEEAK 721
Query: 722 VFANQVGYPVLIRPSYVLSGAAMSVVTGEHELEVKLTTASDVSPDHPVVMSKFIEGAQEI 781
+FA++V YPVLIRPSYVLSGAAMSVV E EL+ KLT ASDVSPDHPVVMSKFIEGAQEI
Sbjct: 722 LFASKVNYPVLIRPSYVLSGAAMSVVNNEEELKAKLTLASDVSPDHPVVMSKFIEGAQEI 781
Query: 782 DVDAVAHNGMVLVHAISEHVENAGIHSGDATLVLPPQNLSQNIKDRLKEIADKVAKAWNI 841
DVDAVA+NG VLVHAISEHVENAG+HSGDA+LVLPPQ+LS ++K LK+IADKVAKAW I
Sbjct: 782 DVDAVAYNGNVLVHAISEHVENAGVHSGDASLVLPPQHLSDDVKIALKDIADKVAKAWKI 841
Query: 842 TGPFNMQIIKDDRDEGVSLKVIECNIRASRSFPFVSKVLGVNFIEAAVQAFLSKD-VPEP 900
TGPFNMQIIKD +LKVIECNIRASRSFPFVSKVLGVNFIE AV+AFL D VP+P
Sbjct: 842 TGPFNMQIIKDGEH---TLKVIECNIRASRSFPFVSKVLGVNFIEIAVKAFLGGDIVPKP 898
Query: 901 VNLM-DKAYDYVATKVPQFSFTRLAGADPFLGVEMASTGEVASFGSNALESYWTAIQSTM 959
V+LM +K YDYVATKVPQFSFTRLAGADPFLGVEMASTGEVASFG + +ESYWTAIQSTM
Sbjct: 899 VDLMLNKKYDYVATKVPQFSFTRLAGADPFLGVEMASTGEVASFGRDLIESYWTAIQSTM 958
Query: 960 NFNVPLPPSGILFGGDLSKNYLGEVVKYVAPLGYKLYATNEDTKKYLETF--SKGVSVEL 1017
NF+VPLPPSGILFGGD S+ YLG+V VA +GY++Y TNE TK YL+ K V L
Sbjct: 959 NFHVPLPPSGILFGGDTSREYLGQVASIVATIGYRIYTTNETTKTYLQEHIKEKNAKVSL 1018
Query: 1018 IEFPKNDKRKLRELFQAKDISAVFNLAAKRAESLEDVDYIMRRNAIDFALPLFNEPQTAM 1077
I+FPKNDKRKLRELFQ DI AVFNLA+KRAES +DVDYIMRRNAIDFA+PLFNEPQTA+
Sbjct: 1019 IKFPKNDKRKLRELFQEYDIKAVFNLASKRAESTDDVDYIMRRNAIDFAIPLFNEPQTAL 1078
Query: 1078 LFAKAMSLKIAEKVKVLESKDVIVPHEVRTWSEYLHCK 1115
LFAK + KIAEK+K+LES DVIVP EVR+W E++ K
Sbjct: 1079 LFAKCLKAKIAEKIKILESHDVIVPPEVRSWDEFIGFK 1116
>SPBC215.08c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1160
Score = 1399 bits (3620), Expect = 0.0
Identities = 704/1089 (64%), Positives = 855/1089 (77%), Gaps = 20/1089 (1%)
Query: 27 EGVESVLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIATNQTSHSLADEI 86
E V+ V+V+GSGGLSIGQAGEFDYSG+QAIKAL+E++ TIL+NPNIAT Q+SHSLADEI
Sbjct: 84 EKVKKVVVVGSGGLSIGQAGEFDYSGAQAIKALRESSVHTILINPNIATIQSSHSLADEI 143
Query: 87 YYLPVTPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKTLE 146
Y+LPVT EY+T++IERE PD ILLTFGGQT LN G+ LD GV A+ ++KVLGTPI TL+
Sbjct: 144 YFLPVTAEYLTHLIERENPDGILLTFGGQTALNVGIQLDDMGVFARNHVKVLGTPISTLK 203
Query: 147 TSEDRDLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFANN 206
TSEDRDLFA+AL EI+IP AES+A TVD AL+AA+ V +PVI+RSAY+LGGLGSGFANN
Sbjct: 204 TSEDRDLFAKALNEINIPIAESVAVSTVDEALQAAEKVSYPVIIRSAYSLGGLGSGFANN 263
Query: 207 AQEMKQLASQSLSLAPQILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGIHTGD 266
+E++ +A++SLSL PQILVEKSLKGWKEVEYEVVRD NCITVCNMENFDPLGIHTGD
Sbjct: 264 KEELQSMAAKSLSLTPQILVEKSLKGWKEVEYEVVRDAANNCITVCNMENFDPLGIHTGD 323
Query: 267 SIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXX 326
SIV APSQTLSDEE+HMLR+AAIKIIRHLGV+GECNVQYALSP+SL+YRVIEVN
Sbjct: 324 SIVVAPSQTLSDEEYHMLRTAAIKIIRHLGVVGECNVQYALSPNSLEYRVIEVNARLSRS 383
Query: 327 XXXXXXXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSLDYIVAKIPRWDLSKFQ 386
TGYPLAYTAAKIALG+TLPELPN +TKTT ANFEPSLDY+V KIPRWDLSKFQ
Sbjct: 384 SALASKATGYPLAYTAAKIALGHTLPELPNAVTKTTTANFEPSLDYVVTKIPRWDLSKFQ 443
Query: 387 HVNRSVGSSMKSVGEVMAIGRNFEEAFQKAIRQIDPSFIGFQGSDEFDDLDNALSEPTDR 446
+VNR +GSSMKSVGEVMA+GR FEE+ QKA+RQ+DPSF+GF F DLDNALS PTDR
Sbjct: 444 YVNREIGSSMKSVGEVMAVGRTFEESLQKALRQVDPSFLGFMAM-PFKDLDNALSVPTDR 502
Query: 447 RWLAVGQALIHEGYSVEKVHELTKIDSWFLFKCMNIVDMYKDLEQVNDXXXXXXXXXXXX 506
R+ AV +A++++GYS++K+H+LTKID WFL K N+ +YK+LE++
Sbjct: 503 RFFAVVEAMLNQGYSIDKIHDLTKIDKWFLSKLANMAKVYKELEEIGSLYGLNKEIMLRA 562
Query: 507 XXXGFSDAQIALCLNKGSDSRTSELEVRSYRKSFGIVPFVKRIDTLAAEFPAQTNYLYTT 566
GFSD QI+ + SEL+VR+ RK + P+VK+IDTLAAEFPA TNYLYT+
Sbjct: 563 KKTGFSDLQISKLVG------ASELDVRARRKRLDVHPWVKKIDTLAAEFPAHTNYLYTS 616
Query: 567 YNATKSDIEFTDNGVLVLGSGVYRIGSSVEFDWCAVNTTKALRKEGKKTIMINYNPETVS 626
YNA+ DI+F ++G +VLGSGVYRIGSSVEFDWC V+ + LRK G TIM+NYNPETVS
Sbjct: 617 YNASSHDIDFNEHGTMVLGSGVYRIGSSVEFDWCGVSCARTLRKLGHSTIMVNYNPETVS 676
Query: 627 TDFDEVDRLYFEELSFERVMDIYELENSEGCVISVGGQLPQNIALKLLHNGAHILGTSPE 686
TDFDE +RLYFEELS+ERVMDIYE+E + G V+SVGGQLPQNIALKL GA +LGT P
Sbjct: 677 TDFDECERLYFEELSYERVMDIYEMETASGIVVSVGGQLPQNIALKLQETGAKVLGTDPL 736
Query: 687 DIDKAENRHKFSTILDSIGVNQPEWSELSSVEEAKVFANQVGYPVLIRPSYVLSGAAMSV 746
ID AE+RHKFS ILD IGV+QP W EL+SV EA FAN VGYPVL+RPSYVLSGAAMSV
Sbjct: 737 MIDSAEDRHKFSQILDKIGVDQPAWKELTSVAEASKFANAVGYPVLVRPSYVLSGAAMSV 796
Query: 747 VTGEHELEVKLTTASDVSPDHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAISEHVENAGI 806
+ E L+ KL AS VSPDHPVV++KFIEGA+E+DVDAVA G +LVHA+SEHVENAG+
Sbjct: 797 IRDESSLKDKLENASAVSPDHPVVITKFIEGARELDVDAVASKGKLLVHAVSEHVENAGV 856
Query: 807 HSGDATLVLPPQNLSQNIKDRLKEIADKVAKAWNITGPFNMQII---KDDRDEGVSLKVI 863
HSGDAT+ LPP +LS++I R KEIA+KV KA+ ITGP+NMQII D+ + LKVI
Sbjct: 857 HSGDATIALPPYSLSEDILSRCKEIAEKVCKAFQITGPYNMQIILAQNPDKPDTPDLKVI 916
Query: 864 ECNIRASRSFPFVSKVLGVNFIEAAVQAFLSKDVPEPVNLMDKAYDYVATKVPQFSFTRL 923
ECN+RASRSFPFVSK LGVNFI+ A ++ + ++VP +LM DYV KVPQFS+TRL
Sbjct: 917 ECNLRASRSFPFVSKTLGVNFIDVATRSIIDQEVPAARDLMAVHRDYVCVKVPQFSWTRL 976
Query: 924 AGADPFLGVEMASTGEVASFGSNALESYWTAIQSTMNFNVPLPPSGILFGGDLSKNYLGE 983
AGADP+LGVEM+STGEVA FG + E+YW A+QST NF +PLP GIL GGD + L
Sbjct: 977 AGADPYLGVEMSSTGEVACFGKDVKEAYWAALQSTQNFKIPLPGQGILLGGD--RPELAG 1034
Query: 984 VVKYVAPLGYKLYATNEDTKKYLETFSKGVSVELIEFPKNDKRKLRELFQAKDISAVFNL 1043
+ ++ LGYKLY N+D K L+ S E++EFP DKR LR +F+ +I +VFNL
Sbjct: 1035 IAADLSKLGYKLYVANKDAAKLLQP----TSAEVVEFPVKDKRALRAIFEKYNIRSVFNL 1090
Query: 1044 AAKRAESLEDVDYIMRRNAIDFALPLFNEPQTAMLFAKAMSLKIAEKVKVLESKDVIVPH 1103
A+ R +++ D DY+MRRNA+DF + L N+ A LF +++ EK+ + S+ +P
Sbjct: 1091 ASARGKNVLDQDYVMRRNAVDFNVTLINDVNCAKLFVESLK----EKLPSVLSEKKEMPS 1146
Query: 1104 EVRTWSEYL 1112
EV+ WSE++
Sbjct: 1147 EVKRWSEWI 1155
>YJL130c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2214
Score = 1096 bits (2834), Expect = 0.0
Identities = 582/1069 (54%), Positives = 742/1069 (68%), Gaps = 29/1069 (2%)
Query: 30 ESVLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIATNQTSHSLADEIYYL 89
+ VLV+GSGGLSIGQAGEFDYSGSQAIKALKE TIL+NPNIAT QTS LAD++Y++
Sbjct: 439 KKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYFV 498
Query: 90 PVTPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKTLETSE 149
PVT E++ +I ERPDAI +TFGGQT L+ G+A+ +KVLGTPI T+ T+E
Sbjct: 499 PVTAEFVRKVILHERPDAIYVTFGGQTALSVGIAMKDE--FEALGVKVLGTPIDTIITTE 556
Query: 150 DRDLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQE 209
DR+LF+ A+ EI+ A+S A +VD AL A +GFPVIVR+AYALGGLGSGFANN +E
Sbjct: 557 DRELFSNAIDEINEKCAKSQAANSVDEALAAVKEIGFPVIVRAAYALGGLGSGFANNEKE 616
Query: 210 MKQLASQSLSLAPQILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGIHTGDSIV 269
+ L + + S +PQ+LVEKS+KGWKEVEYEVVRD NCITVCNMENFDPLGIHTGDSIV
Sbjct: 617 LVDLCNVAFSSSPQVLVEKSMKGWKEVEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIV 676
Query: 270 FAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXXX 329
APSQTLSDE+++MLR+ A+ +IRHLGV+GECN+QYAL+P S DY +IEVN
Sbjct: 677 VAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPVSKDYCIIEVNARLSRSSAL 736
Query: 330 XXXXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSLDYIVAKIPRWDLSKFQHVN 389
TGYPLAYTAAK+ L L E+ N +TK+T A FEPSLDY V K+PRWDL KF V+
Sbjct: 737 ASKATGYPLAYTAAKLGLNIPLNEVKNSVTKSTCACFEPSLDYCVVKMPRWDLKKFTRVS 796
Query: 390 RSVGSSMKSVGEVMAIGRNFEEAFQKAIRQIDPSFIGFQGSDEFDDLDNALSEPTDRRWL 449
+ SSMKSVGEVM+IGR FEEA QKAIR + + +GF +D D+D L+ PTD R
Sbjct: 797 TELSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYANLGFNETDLDIDIDYELNNPTDMRVF 856
Query: 450 AVGQALIHEGYSVEKVHELTKIDSWFLFKCMNIVDMYKDLEQVNDXXXXXXXXXXXXXXX 509
A+ A +GYSV+KV E+T+ID WFL K ++V + +
Sbjct: 857 AIANAFAKKGYSVDKVWEMTRIDKWFLNKLHDLVQFAEKISSFGTKEELPSLVLRQAKQL 916
Query: 510 GFSDAQIALCLNKGSDSRTSELEVRSYRKSFGIVPFVKRIDTLAAEFPAQTNYLYTTYNA 569
GF D QIA L+ ++E+ +R RK +GI PFVK+IDT+AAEFPA TNYLY TYNA
Sbjct: 917 GFDDRQIARFLD------SNEVAIRRLRKEYGITPFVKQIDTVAAEFPAYTNYLYMTYNA 970
Query: 570 TKSDIEFTDNGVLVLGSGVYRIGSSVEFDWCAVNTTKALRKEGKKTIMINYNPETVSTDF 629
D+ F D+GV+VLGSGVYRIGSSVEFDWCAV + LR KTIM+NYNPETVSTD+
Sbjct: 971 DSHDLSFDDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRANNIKTIMVNYNPETVSTDY 1030
Query: 630 DEVDRLYFEELSFERVMDIYELENSEGCVISVGGQLPQNIALKLLHNGAHILGTSPEDID 689
DE DRLYFE ++ ERV+DIYE+ENS G V+S+GGQ NIA+ L ILGTSP+ ID
Sbjct: 1031 DEADRLYFETINLERVLDIYEIENSSGVVVSMGGQTSNNIAMTLHRENVKILGTSPDMID 1090
Query: 690 KAENRHKFSTILDSIGVNQPEWSELSSVEEAKVFANQVGYPVLIRPSYVLSGAAMSVVTG 749
AENR+KFS +LD IGV+QP W EL+S++EA+ FA +VGYPVL+RPSYVLSGAAM+ V
Sbjct: 1091 SAENRYKFSRMLDQIGVDQPAWKELTSMDEAESFAEKVGYPVLVRPSYVLSGAAMNTVYS 1150
Query: 750 EHELEVKLTTASDVSPDHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAISEHVENAGIHSG 809
+++LE L A +VS D+PVV++K+IE A+EI++DAVA NG +++H +SEHVENAG+HSG
Sbjct: 1151 KNDLESYLNQAVEVSRDYPVVITKYIENAKEIEMDAVARNGELVMHVVSEHVENAGVHSG 1210
Query: 810 DATLVLPPQNLSQNIKDRLKEIADKVAKAWNITGPFNMQIIKDDRDEGVSLKVIECNIRA 869
DATL++PPQ+L+ DR+ K+ KA ITGP+N+Q I D + +KVIECN+RA
Sbjct: 1211 DATLIVPPQDLAPETVDRIVVATAKIGKALKITGPYNIQFIAKDNE----IKVIECNVRA 1266
Query: 870 SRSFPFVSKVLGVNFIEAAVQAFLSKDV-PEPVNLMDKAYDYVATKVPQFSFTRLAGADP 928
SRSFPF+SKV+GVN IE A +A + + P PV + DYVA KVPQFSF RLAGADP
Sbjct: 1267 SRSFPFISKVVGVNLIELATKAIMGLPLTPYPVEKLPD--DYVAVKVPQFSFPRLAGADP 1324
Query: 929 FLGVEMASTGEVASFGSNALESYWTAIQSTMNFNVPLPPSGILFGGDLSKNYLGEVVKYV 988
LGVEMASTGEVA+FG + E+Y ++ +T F +P + G K L V+ +
Sbjct: 1325 VLGVEMASTGEVATFGHSKYEAYLKSLLAT-GFKLPKKNILLSIGSYKEKQELLSSVQKL 1383
Query: 989 APLGYKLYATNEDTKKYLETFSKGVSVELIEFPKND------KRKLRELFQAKDISAVFN 1042
+GYKL+AT+ T +L G++V+ +E D + L + +I N
Sbjct: 1384 YNMGYKLFATS-GTADFLS--EHGIAVQYLEVLNKDDDDQKSEYSLTQHLANNEIDLYIN 1440
Query: 1043 LAA----KRAESLEDVDYIMRRNAIDFALPLFNEPQTAMLFAKAMSLKI 1087
L + +R S Y RR A+D+++PL + A L +A+S I
Sbjct: 1441 LPSANRFRRPASYVSKGYKTRRLAVDYSVPLVTNVKCAKLLIEAISRNI 1489
>Hs18105007 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2225
Score = 1077 bits (2786), Expect = 0.0
Identities = 581/1063 (54%), Positives = 737/1063 (68%), Gaps = 29/1063 (2%)
Query: 32 VLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIATNQTSHSLADEIYYLPV 91
VL++GSGGLSIGQAGEFDYSGSQAIKALKE N +T+L+NPNIAT QTS LAD++Y+LP+
Sbjct: 396 VLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPI 455
Query: 92 TPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKTLETSEDR 151
TP Y+T +I ERPD +LLTFGGQT LNCGV L KAGVLA+Y ++VLGTP++T+E +EDR
Sbjct: 456 TPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDR 515
Query: 152 DLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMK 211
FA + EI A S A +++ A AA+ +G+PV+VR+A+ALGGLGSGFA+N +E+
Sbjct: 516 RAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELS 575
Query: 212 QLASQSLSLAPQILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGIHTGDSIVFA 271
L + + + Q+LV+KSLKGWKE+EYEVVRD GNC+TVCNMEN DPLGIHTG+SIV A
Sbjct: 576 ALVAPAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVA 635
Query: 272 PSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXXXXX 331
PSQTL+D E+ +LR AIK+ +HLG++GECNVQYAL+P+S Y +IEVN
Sbjct: 636 PSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALAS 695
Query: 332 XXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSLDYIVAKIPRWDLSKFQHVNRS 391
TGYPLAY AAK+ALG LPEL N +T T A FEPS+DY V KIPRWDLSKF V+
Sbjct: 696 KATGYPLAYVAAKLALGIPLPELRNSVTGGTAA-FEPSVDYCVVKIPRWDLSKFLRVSTK 754
Query: 392 VGSSMKSVGEVMAIGRNFEEAFQKAIRQIDPSFIGFQGSDEFDDLDNALSEPTDRRWLAV 451
+GS MKSVGEVM IGR+FEEAFQKA+R +D + +GF + + D L PTD+R V
Sbjct: 755 IGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVK-PVSDMELETPTDKRIFVV 813
Query: 452 GQALIHEGYSVEKVHELTKIDSWFLFKCMNIVDMYKDLEQVNDXXXXXXXXXXXXXXXGF 511
AL GYSV++++ELT+ID WFL + I+ + LEQ + GF
Sbjct: 814 AAAL-WAGYSVDRLYELTRIDRWFLHRMKRIIAHAQLLEQ-HRGQPLPPDLLQQAKCLGF 871
Query: 512 SDAQIALCLNKGSDSRTSELEVRSYRKSFGIVPFVKRIDTLAAEFPAQTNYLYTTYNATK 571
SD QIAL + ++EL VR R+ GI P VK+IDT+AAE+PAQTNYLY TY T
Sbjct: 872 SDKQIALAV------LSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGTT 925
Query: 572 SDIEFTDNGVLVLGSGVYRIGSSVEFDWCAVNTTKALRKEGKKTIMINYNPETVSTDFDE 631
D+ F VLVLGSGVYRIGSSVEFDWCAV + LRK G KTIM+NYNPETVSTD+D
Sbjct: 926 HDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDM 985
Query: 632 VDRLYFEELSFERVMDIYELENSEGCVISVGGQLPQNIALKLLHNGAHILGTSPEDIDKA 691
DRLYF+E+SFE VMDIYELEN EG ++S+GGQLP N+A+ L +LGTSPE ID A
Sbjct: 986 CDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSA 1045
Query: 692 ENRHKFSTILDSIGVNQPEWSELSSVEEAKVFANQVGYPVLIRPSYVLSGAAMSVVTGEH 751
ENR KFS +LD+IG++QP+W ELS +E A+ F VGYP ++RPSYVLSGAAM+V +
Sbjct: 1046 ENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDG 1105
Query: 752 ELEVKLTTASDVSPDHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAISEHVENAGIHSGDA 811
+LE L++A+ VS +HPVV+SKFI+ A+EIDVDAVA +G+V AISEHVENAG+HSGDA
Sbjct: 1106 DLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDA 1165
Query: 812 TLVLPPQNLSQNIKDRLKEIADKVAKAWNITGPFNMQII-KDDRDEGVSLKVIECNIRAS 870
TLV PPQ+++ +R+K I V + +TGPFN+Q+I KDD+ LKVIECN+R S
Sbjct: 1166 TLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQ-----LKVIECNVRVS 1220
Query: 871 RSFPFVSKVLGVNFIEAAVQAFLSKDVPEPVNLMDKAYDYVATKVPQFSFTRLAGADPFL 930
RSFPFVSK LGV+ + A + + ++V EPV LM + V KVPQFSF+RLAGAD L
Sbjct: 1221 RSFPFVSKTLGVDLVALATRVIMGEEV-EPVGLMTGS-GVVGVKVPQFSFSRLAGADVVL 1278
Query: 931 GVEMASTGEVASFGSNALESYWTAIQSTMNFNVPLPPSGILFGGDLSKNYLGEVVKYVAP 990
GVEM STGEVA FG + E+Y A+ ST F +P + G +K+ L V+ +
Sbjct: 1279 GVEMTSTGEVAGFGESRCEAYLKAMLST-GFKIPKKNILLTIGSYKNKSELLPTVRLLES 1337
Query: 991 LGYKLYATNEDTKKYLETFSKGVSV-----ELIEFPKNDKRKLRELFQAKDISAVFNLA- 1044
LGY LYA+ Y E K +V E ++ +R + E K+ V NL+
Sbjct: 1338 LGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILEQLAEKNFELVINLSM 1397
Query: 1045 ----AKRAESLEDVDYIMRRNAIDFALPLFNEPQTAMLFAKAM 1083
+R S Y RR A DF++PL + + LF +A+
Sbjct: 1398 RGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL 1440
>7293258 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2189
Score = 1061 bits (2745), Expect = 0.0
Identities = 569/1078 (52%), Positives = 731/1078 (67%), Gaps = 49/1078 (4%)
Query: 11 PTTSAFNTDEYNPQLVEGVESVLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVN 70
PTT A ++ P+ VL++GSGGLSIGQAGEFDYSGSQAIKA++E+N +T+L+N
Sbjct: 391 PTTPAIDSAPVMPR------KVLILGSGGLSIGQAGEFDYSGSQAIKAMRESNIQTVLIN 444
Query: 71 PNIATNQTSHSLADEIYYLPVTPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVL 130
PNIAT QTS +AD+ Y+LP+TP Y+ +I+ ERP+ +LLTFGGQT LNCGV L++AGV
Sbjct: 445 PNIATVQTSKGMADKCYFLPLTPHYVEQVIKSERPNGVLLTFGGQTALNCGVQLERAGVF 504
Query: 131 AKYNIKVLGTPIKTLETSEDRDLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIV 190
+KYN+++LGTPI+++ +EDR LFA+ + EI A S A +V AL+AA +G+PV+
Sbjct: 505 SKYNVRILGTPIQSIIETEDRKLFAERVNEIGEQVAPSEAVYSVAQALDAASRLGYPVMA 564
Query: 191 RSAYALGGLGSGFANNAQEMKQLASQSLSLAPQILVEKSLKGWKEVEYEVVRDRVGNCIT 250
R+A++LGGLGSGFANN +E++ LA Q+L+ + Q++V+KSLKGWKEVEYEVVRD NCIT
Sbjct: 565 RAAFSLGGLGSGFANNEEELQSLAQQALAHSSQLIVDKSLKGWKEVEYEVVRDAYNNCIT 624
Query: 251 VCNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPD 310
VCNMENFDPLGIHTG+SIV APSQTLSD E+ MLRS A+K+IRH GV+GECN+QYAL P
Sbjct: 625 VCNMENFDPLGIHTGESIVVAPSQTLSDREYQMLRSTALKVIRHFGVVGECNIQYALCPH 684
Query: 311 SLDYRVIEVNXXXXXXXXXXXXXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSL 370
S Y +IEVN TGYPLAY AAK+ALG LP++ N +T T A FEPSL
Sbjct: 685 SEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGLPLPDIKNSVTGNTTACFEPSL 744
Query: 371 DYIVAKIPRWDLSKFQHVNRSVGSSMKSVGEVMAIGRNFEEAFQKAIRQIDPSFIGFQGS 430
DY V KIPRWDL+KF V++ +GSSMKSVGEVMAIGRNFEEAFQKA+R +D +GF
Sbjct: 745 DYCVVKIPRWDLAKFVRVSKHIGSSMKSVGEVMAIGRNFEEAFQKALRMVDSDVLGFDPD 804
Query: 431 D---EFDDLDNALSEPTDRRWLAVGQALIHEGYSVEKVHELTKIDSWFLFKCMNIVDMYK 487
+ L LSEPTDRR + AL G S+ ++H+LT ID WFL K I+ +
Sbjct: 805 VVPLNKEQLAEQLSEPTDRRPFVIAAAL-QLGMSLRELHQLTNIDYWFLEKLERIILLQS 863
Query: 488 DLEQVNDXXXXXXXXXXXXXXXGFSDAQIALCLNKGSDSRTSELEVRSYRKSFGIVPFVK 547
L + GFSD QIA + +++EL VR R+ FGI P VK
Sbjct: 864 LL--TRNGSRTDAALLLKAKRFGFSDKQIAKYI------KSTELAVRHQRQEFGIRPHVK 915
Query: 548 RIDTLAAEFPAQTNYLYTTYNATKSDIEFTDNGVLVLGSGVYRIGSSVEFDWCAVNTTKA 607
+IDT+A E+PA TNYLY TYN ++ D++F +V+GSGVYRIGSSVEFDWCAV +
Sbjct: 916 QIDTVAGEWPASTNYLYHTYNGSEHDVDFPGGHTIVVGSGVYRIGSSVEFDWCAVGCLRE 975
Query: 608 LRKEGKKTIMINYNPETVSTDFDEVDRLYFEELSFERVMDIYELENSEGCVISVGGQLPQ 667
LRK + TIMINYNPETVSTD+D DRLYFEE+SFE VMDIYE+ENSEG ++S+GGQLP
Sbjct: 976 LRKLQRPTIMINYNPETVSTDYDMCDRLYFEEISFEVVMDIYEMENSEGIILSMGGQLPN 1035
Query: 668 NIALKLLHNGAHILGTSPEDIDKAENRHKFSTILDSIGVNQPEWSELSSVEEAKVFANQV 727
NIA+ L A +LGTSPE ID AENR KFS +LD G+ QP W EL++++ A F +V
Sbjct: 1036 NIAMDLHRQQAKVLGTSPESIDCAENRFKFSRMLDRKGILQPRWKELTNLQSAIEFCEEV 1095
Query: 728 GYPVLIRPSYVLSGAAMSVVTGEHELEVKLTTASDVSPDHPVVMSKFIEGAQEIDVDAVA 787
GYP L+RPSYVLSGAAM+V +LE L AS+VS +HPVV+SKF+ A+EIDVDAVA
Sbjct: 1096 GYPCLVRPSYVLSGAAMNVAYSNQDLETYLNAASEVSREHPVVISKFLTEAKEIDVDAVA 1155
Query: 788 HNGMVLVHAISEHVENAGIHSGDATLVLPPQNLSQNIKDRLKEIADKVAKAWNITGPFNM 847
+G +L A+SEHVENAG+HSGDATLV PPQ+L+ + +K I +A ++TGPFNM
Sbjct: 1156 SDGRILCMAVSEHVENAGVHSGDATLVTPPQDLNAETLEAIKRITCDLASVLDVTGPFNM 1215
Query: 848 QIIKDDRDEGVSLKVIECNIRASRSFPFVSKVLGVNFIEAAVQAFLSKDVPEPVNLMDKA 907
Q+I + + LKVIECN+R SRSFPFVSK L +F+ A +A + DV EP++++
Sbjct: 1216 QLIAKNNE----LKVIECNVRVSRSFPFVSKTLDHDFVATATRAIVGLDV-EPLDVL-HG 1269
Query: 908 YDYVATKVPQFSFTRLAGADPFLGVEMASTGEVASFGSNALESYWTAIQSTMNFNVPLPP 967
V KVPQFSF+RLAGAD LGVEMASTGEVA FG N E+Y A+ ST F +P
Sbjct: 1270 VGKVGVKVPQFSFSRLAGADVQLGVEMASTGEVACFGDNRYEAYLKAMMST-GFQIPKNA 1328
Query: 968 SGILFGGDLSKNYLGEVVKYVAPLGYKLYATNEDTKKYLETFSKGVSVELIEFPKNDKRK 1027
+ G K L ++ +A +GYKLYA+ + T V P +++R
Sbjct: 1329 VLLSIGSFKHKMELLPSIRDLAKMGYKLYAS-------MGTGDFYAXVRPGHQPPDERR- 1380
Query: 1028 LRELFQAKDISAVFNLAAKRAESLEDVDYIMRRNAIDFALPLFNEPQTAMLFAKAMSL 1085
+ S Y RR A+D+++PL + + L ++M +
Sbjct: 1381 ----------------GCQAVSSFMTHGYRTRRLAVDYSIPLVTDVKCTKLLVESMRM 1422
>SPAC22G7.06c [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2244
Score = 1061 bits (2743), Expect = 0.0
Identities = 566/1060 (53%), Positives = 726/1060 (68%), Gaps = 27/1060 (2%)
Query: 32 VLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIATNQTSHSLADEIYYLPV 91
VL++GSGGLSIGQAGEFDYSGSQAIKAL+E TIL+NPNIAT QTS LAD++Y+LPV
Sbjct: 477 VLILGSGGLSIGQAGEFDYSGSQAIKALREEGIYTILINPNIATIQTSKGLADKVYFLPV 536
Query: 92 TPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKTLETSEDR 151
+++ +I++ERPD+I +TFGGQT LN G+ L + +KVLGTPI T+ T+EDR
Sbjct: 537 NADFVRKVIKQERPDSIYVTFGGQTALNVGIELKDE--FEQLGVKVLGTPIDTIITTEDR 594
Query: 152 DLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMK 211
+LFA+A+ EI+ A+S + +++ A++ + + FPVIVR+AYALGGLGSGFA+N E+
Sbjct: 595 ELFARAMDEINEKCAKSASASSIEEAIKVSKDISFPVIVRAAYALGGLGSGFADNEAELI 654
Query: 212 QLASQSLSLAPQILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGIHTGDSIVFA 271
L + + + +PQ+L+E+S+KGWKE+EYEVVRD NCITVCNMENFDPLGIHTGDSIV A
Sbjct: 655 DLCTLAFATSPQVLIERSMKGWKEIEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVVA 714
Query: 272 PSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXXXXX 331
PSQTL+DE+++MLR+ A+ +IRHLGV+GECN+QYAL+P + +Y +IEVN
Sbjct: 715 PSQTLTDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPFTKEYCIIEVNARLSRSSALAS 774
Query: 332 XXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSLDYIVAKIPRWDLSKFQHVNRS 391
TGYPLA+TAAK+ L L E+ N +TK T A FEPSLDY+V KIPRWDL KF V+
Sbjct: 775 KATGYPLAFTAAKLGLNIPLNEVKNSVTKVTCACFEPSLDYVVVKIPRWDLKKFTRVSTQ 834
Query: 392 VGSSMKSVGEVMAIGRNFEEAFQKAIRQIDPSFIGFQGSDEFDDLDNALSEPTDRRWLAV 451
+ S+MKSVGEVM+IGR FEEA QKAIR ID S GF D +D L P+D+R A+
Sbjct: 835 LSSAMKSVGEVMSIGRTFEEAIQKAIRAIDYSNTGFNVKDALMSIDTELQTPSDQRLFAI 894
Query: 452 GQALIHEGYSVEKVHELTKIDSWFLFKCMNIVDMYKDLEQVNDXXXXXXXXXXXXXXXGF 511
A+ GYSV+++ ELT+ID WFL K M ++ L +D GF
Sbjct: 895 ANAMA-SGYSVDRIWELTRIDKWFLEKLMGLIRT-SQLISKHDISSLPISLLKTAKQLGF 952
Query: 512 SDAQIALCLNKGSDSRTSELEVRSYRKSFGIVPFVKRIDTLAAEFPAQTNYLYTTYNATK 571
+D QIA +N ++EL VR R GI PFVK+IDT+AAEFPA TNYLYTTYNA +
Sbjct: 953 ADVQIAAFMN------STELAVRRIRTEAGIRPFVKQIDTVAAEFPAFTNYLYTTYNAVE 1006
Query: 572 SDIEFTDNGVLVLGSGVYRIGSSVEFDWCAVNTTKALRKEGKKTIMINYNPETVSTDFDE 631
DI F D GV+VLGSGVYRIGSSVEFDWCAV + LR G KTIM+NYNPETVSTD+DE
Sbjct: 1007 HDIHFNDKGVMVLGSGVYRIGSSVEFDWCAVRAVRTLRDRGVKTIMVNYNPETVSTDYDE 1066
Query: 632 VDRLYFEELSFERVMDIYELENSEGCVISVGGQLPQNIALKLLHNGAHILGTSPEDIDKA 691
DRLYFE + E V+DIYE E+S G +I++GGQ NIAL L ILGTSPE ID A
Sbjct: 1067 ADRLYFENIGLETVLDIYEQESSSGIIIAMGGQTANNIALPLHRENVKILGTSPEMIDGA 1126
Query: 692 ENRHKFSTILDSIGVNQPEWSELSSVEEAKVFANQVGYPVLIRPSYVLSGAAMSVVTGEH 751
ENR KFS +LD IGV+QP+W EL+S +EA F + VGYPVL+RPSYVLSGAAM+ V +
Sbjct: 1127 ENRFKFSRMLDDIGVDQPKWKELTSFDEADKFCDTVGYPVLVRPSYVLSGAAMNTVYSQS 1186
Query: 752 ELEVKLTTASDVSPDHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAISEHVENAGIHSGDA 811
+L L A ++ DHPVV+SK+IE A+EI++DAVA G +++H ISEHVENAG+HSGDA
Sbjct: 1187 DLHSYLQQAVAINKDHPVVISKYIENAKEIELDAVAREGKMVMHVISEHVENAGVHSGDA 1246
Query: 812 TLVLPPQNLSQNIKDRLKEIADKVAKAWNITGPFNMQIIKDDRDEGVSLKVIECNIRASR 871
TLVLPPQ+L+ +R+ + A K+ +A NITGP+N+Q I D + +KVIECN+RASR
Sbjct: 1247 TLVLPPQDLAPTTIERIVDAAAKIGEALNITGPYNIQFIAKDNE----IKVIECNVRASR 1302
Query: 872 SFPFVSKVLGVNFIEAAVQAFLSKDVPEPVNLMDKAYDYVATKVPQFSFTRLAGADPFLG 931
SFPFVSKV+GV+ I A + + +P +D DYVA KVPQFSF+RL+GADP LG
Sbjct: 1303 SFPFVSKVIGVDMISMATDVIMGNPI-QPYPDVDLPRDYVAVKVPQFSFSRLSGADPVLG 1361
Query: 932 VEMASTGEVASFGSNALESYWTAIQSTMNFNVPLPPSGILFGGDLSKNYLGEVVKYVAPL 991
VEMASTGEVA FG N E+Y A+ ST F +P I G K L VK +
Sbjct: 1362 VEMASTGEVACFGHNKFEAYLKAMIST-GFRLPKKNILISIGSYKEKAELLPYVKKLYEN 1420
Query: 992 GYKLYATNEDTKKYLETFSKGVSVE-LIEFP---KNDKRKLRELFQAKDISAVFNLAA-- 1045
Y ++AT + ++E+ GV + L + P N++ L I NL +
Sbjct: 1421 NYNIFATAGTSDYFMES---GVPCKYLADLPAEEANNEYSLSAHLANNMIDMYINLPSNN 1477
Query: 1046 --KRAESLEDVDYIMRRNAIDFALPLFNEPQTAMLFAKAM 1083
+R + Y RR AID+++PL + A L +A+
Sbjct: 1478 RYRRPANYISSGYKSRRLAIDYSVPLVTNVKCAKLMIEAI 1517
Score = 164 bits (414), Expect = 9e-40
Identities = 105/390 (26%), Positives = 187/390 (47%), Gaps = 20/390 (5%)
Query: 30 ESVLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIATNQTSHSLADEIYYL 89
+ V+V+GSG IG + EFD+ +A++ L++ KTI+VN N T T + AD +Y+
Sbjct: 1014 KGVMVLGSGVYRIGSSVEFDWCAVRAVRTLRDRGVKTIMVNYNPETVSTDYDEADRLYFE 1073
Query: 90 PVTPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKTLETSE 149
+ E + I E+E I++ GGQT N + L + N+K+LGT + ++ +E
Sbjct: 1074 NIGLETVLDIYEQESSSGIIIAMGGQTANNIALPLHRE------NVKILGTSPEMIDGAE 1127
Query: 150 DRDLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQE 209
+R F++ L +I + + + D A + D VG+PV+VR +Y L G + +
Sbjct: 1128 NRFKFSRMLDDIGVDQPKWKELTSFDEADKFCDTVGYPVLVRPSYVLSGAAMNTVYSQSD 1187
Query: 210 MKQLASQSLSLAPQ--ILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGIHTGDS 267
+ Q++++ +++ K ++ KE+E + V R G + E+ + G+H+GD+
Sbjct: 1188 LHSYLQQAVAINKDHPVVISKYIENAKEIELDAVA-REGKMVMHVISEHVENAGVHSGDA 1246
Query: 268 IVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXX 327
+ P Q L+ + AA KI L + G N+Q+ + + +VIE N
Sbjct: 1247 TLVLPPQDLAPTTIERIVDAAAKIGEALNITGPYNIQFIAKDNEI--KVIECNVRASRSF 1304
Query: 328 XXXXXXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSLDYIVAKIPRWDLSKFQH 387
G + A + +G + P + + DY+ K+P++ S+
Sbjct: 1305 PFVSKVIGVDMISMATDVIMGNPIQPYP---------DVDLPRDYVAVKVPQFSFSRLSG 1355
Query: 388 VNRSVGSSMKSVGEVMAIGRNFEEAFQKAI 417
+ +G M S GEV G N EA+ KA+
Sbjct: 1356 ADPVLGVEMASTGEVACFGHNKFEAYLKAM 1385
>CE03105 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 2198
Score = 1031 bits (2666), Expect = 0.0
Identities = 557/1077 (51%), Positives = 727/1077 (66%), Gaps = 38/1077 (3%)
Query: 32 VLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIATNQTSHSLADEIYYLPV 91
VLV+GSGGL+IGQAGEFDYSG+QA+KAL+E +T+L+NPNIAT QTS AD Y+LP+
Sbjct: 393 VLVLGSGGLTIGQAGEFDYSGAQALKALREEGIRTVLINPNIATVQTSKGFADFTYFLPI 452
Query: 92 TPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKTLETSEDR 151
T EY+T +I++ERP IL TFGGQT LNC + L K G+ +Y+++VLGT I T+ +EDR
Sbjct: 453 TKEYVTDVIKKERPTGILCTFGGQTALNCAIDLYKDGIFEQYDVQVLGTQINTIMKTEDR 512
Query: 152 DLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMK 211
DLF Q + I A S A T++ A+EAA+ +G+PV+VR+AYALGGLGSGFA+N +E+
Sbjct: 513 DLFNQEISAIGEKVAPSKAATTMEGAIEAAEELGYPVLVRAAYALGGLGSGFADNREELI 572
Query: 212 QLASQSLSLAPQILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGIHTGDSIVFA 271
+A Q+L+ + Q+LV+KSLKGWKEVEYEVVRD NCITVCNMEN DPLGIHTG+S+V A
Sbjct: 573 AIAQQALAHSNQVLVDKSLKGWKEVEYEVVRDAYDNCITVCNMENVDPLGIHTGESVVVA 632
Query: 272 PSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXXXXX 331
PSQTLSD E++ LR+ AIK+IRHLG+IGECN+QYAL P SL Y +IEVN
Sbjct: 633 PSQTLSDREYNALRTCAIKVIRHLGIIGECNIQYALDPYSLTYYIIEVNARLSRSSALAS 692
Query: 332 XXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSLDYIVAKIPRWDLSKFQHVNRS 391
TGYPLAY AAK+ALG LP + N +T TT A FEPSLDY V KIPRWDL KF V+
Sbjct: 693 KATGYPLAYVAAKLALGQHLPVIRNSVTGTTTACFEPSLDYCVVKIPRWDLGKFARVSTQ 752
Query: 392 VGSSMKSVGEVMAIGRNFEEAFQKAIRQIDPSFIGFQG-SDEFDDLDNALSEPTDRRWLA 450
+GSSMKSVGEVM IGR FEEA QKA+R + GF + + LS+PTD+R A
Sbjct: 753 IGSSMKSVGEVMGIGRCFEEALQKALRMVSDHADGFSPYTFSRPTTADDLSKPTDKRMFA 812
Query: 451 VGQALIHEGYSVEKVHELTKIDSWFLFKCMNIVDMYKDLEQVNDXXXXXXXXXXXXXXXG 510
+ + + + + VEK HELT+ID WFLF+ NIVD+Y LE+ D G
Sbjct: 813 LARGMYYGDFDVEKAHELTRIDRWFLFRMQNIVDIYHRLEK-TDVNTVSAELLLEAKQAG 871
Query: 511 FSDAQIALCLNKGSDSRTSELEVRSYRKSFGIVPFVKRIDTLAAEFPAQTNYLYTTYNAT 570
FSD QIA + ++E VR R GI P VK+IDT+A E+PAQTNYLYTT+N
Sbjct: 872 FSDRQIAKKIG------SNEYTVREARFVKGITPCVKQIDTVAGEWPAQTNYLYTTFNGI 925
Query: 571 KSDIEFT-DNGVLVLGSGVYRIGSSVEFDWCAVNTTKALRKEGKKTIMINYNPETVSTDF 629
++D+ F N V+VLGSGVYRIGSSVEFD V + L+ G TI +N NPETVSTD+
Sbjct: 926 ENDVSFNMKNAVMVLGSGVYRIGSSVEFDSSCVGCIRELKALGYSTITVNCNPETVSTDY 985
Query: 630 DEVDRLYFEELSFERVMDIYELENSEGCVISVGGQLPQNIALKLLHNGAHILGTSPEDID 689
D DRLYFEE+SFE V+D+Y LE +G +++ GGQ P NIA+ L I GTSP DID
Sbjct: 986 DICDRLYFEEISFETVLDVYHLEKPKGVILAFGGQAPNNIAMSLSRAQVKIFGTSPNDID 1045
Query: 690 KAENRHKFSTILDSIGVNQPEWSELSSVEEAKVFANQVGYPVLIRPSYVLSGAAMSVVTG 749
AE+R KFS L+S+ ++QP+W + ++E+AK F QVGYP LIRPSYVLSGAAM+V
Sbjct: 1046 NAEDRFKFSRKLESLKISQPQWKKSENMEDAKNFCAQVGYPCLIRPSYVLSGAAMNVAHN 1105
Query: 750 EHELEVKLTTASDVSPDHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAISEHVENAGIHSG 809
+LEV L A+ V+ +HPVV+SKFI A+E+DVDAVA +G ++V A+SEH+ENAG+HSG
Sbjct: 1106 AEDLEVFLKQAAVVAKEHPVVVSKFINEAKELDVDAVALDGKLVVMAVSEHIENAGVHSG 1165
Query: 810 DATLVLPPQNLSQNIKDRLKEIADKVAKAWNITGPFNMQIIKDDRDEGVSLKVIECNIRA 869
DATLV P Q++++ DR+K+I ++A+A+N+TGPFNMQ+I + + LKVIECN+R
Sbjct: 1166 DATLVTPAQDMNKLTLDRIKDITFRIAEAFNVTGPFNMQLIAKNNE----LKVIECNLRV 1221
Query: 870 SRSFPFVSKVLGVNFIEAAVQAFLSKDVP------EPVNLMDKAYDYVATKVPQFSFTRL 923
SRSFPFVSK L +F+ A +A ++ D P +P + K V KVPQFSF+RL
Sbjct: 1222 SRSFPFVSKTLDYDFVALATRAMMASDSPAIRATIKPTATLLKGKGRVGVKVPQFSFSRL 1281
Query: 924 AGADPFLGVEMASTGEVASFGSNALESYWTAIQSTMNFNVPLPPSGILFGGDLSKNYLGE 983
AGAD LGVEMASTGEVA FG++ ++Y A+ ST F VP I GG +K + +
Sbjct: 1282 AGADVMLGVEMASTGEVACFGTSRCDAYLKALLST-GFVVPKQNIFISIGGYHAKAEMLK 1340
Query: 984 VVKYVAPLGYKLYATNEDTKKYLETFSKGVSVELIEFP----------KNDKRKLRELFQ 1033
V+ + LGY+LY ++ T Y + S ++V+ +++P + R + E +
Sbjct: 1341 SVEALLKLGYELYG-SKGTADYFQ--SNKINVKPVDWPFEEGSSDEKTASGTRSVVEFLE 1397
Query: 1034 AKDISAVFNL-----AAKRAESLEDVDYIMRRNAIDFALPLFNEPQTAMLFAKAMSL 1085
K+ V NL A R + Y RR AID +PL + + A F +A+ +
Sbjct: 1398 NKEFHLVINLPIRGSGAYRVSAFRTHGYKTRRMAIDNGIPLITDIKCAKTFIQALEM 1454
Score = 147 bits (370), Expect = 1e-34
Identities = 99/389 (25%), Positives = 179/389 (45%), Gaps = 13/389 (3%)
Query: 31 SVLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIATNQTSHSLADEIYYLP 90
+V+V+GSG IG + EFD S I+ LK TI VN N T T + + D +Y+
Sbjct: 936 AVMVLGSGVYRIGSSVEFDSSCVGCIRELKALGYSTITVNCNPETVSTDYDICDRLYFEE 995
Query: 91 VTPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKTLETSED 150
++ E + + E+P ++L FGGQ N ++L +A +K+ GT ++ +ED
Sbjct: 996 ISFETVLDVYHLEKPKGVILAFGGQAPNNIAMSLSRA------QVKIFGTSPNDIDNAED 1049
Query: 151 RDLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEM 210
R F++ L+ + I + E ++ A VG+P ++R +Y L G A+NA+++
Sbjct: 1050 RFKFSRKLESLKISQPQWKKSENMEDAKNFCAQVGYPCLIRPSYVLSGAAMNVAHNAEDL 1109
Query: 211 KQLASQSLSLAPQ--ILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGIHTGDSI 268
+ Q+ +A + ++V K + KE++ + V G + + E+ + G+H+GD+
Sbjct: 1110 EVFLKQAAVVAKEHPVVVSKFINEAKELDVDAVA-LDGKLVVMAVSEHIENAGVHSGDAT 1168
Query: 269 VFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXX 328
+ P+Q ++ ++ +I V G N+Q + L +VIE N
Sbjct: 1169 LVTPAQDMNKLTLDRIKDITFRIAEAFNVTGPFNMQLIAKNNEL--KVIECNLRVSRSFP 1226
Query: 329 XXXXXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSLDYIVAKIPRWDLSKFQHV 388
Y A + + P + I T A + K+P++ S+
Sbjct: 1227 FVSKTLDYDFVALATRAMMASDSPAIRATIKPT--ATLLKGKGRVGVKVPQFSFSRLAGA 1284
Query: 389 NRSVGSSMKSVGEVMAIGRNFEEAFQKAI 417
+ +G M S GEV G + +A+ KA+
Sbjct: 1285 DVMLGVEMASTGEVACFGTSRCDAYLKAL 1313
>Hs21361331 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1500
Score = 1014 bits (2621), Expect = 0.0
Identities = 540/1092 (49%), Positives = 735/1092 (66%), Gaps = 46/1092 (4%)
Query: 29 VESVLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIA---TNQTSHSLADE 85
V VL++GSGGLSIGQAGEFDYSGSQA+KA+KE N KT+L+NPNIA TN+ AD
Sbjct: 422 VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADT 481
Query: 86 IYYLPVTPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKTL 145
+Y+LP+TP+++T +I+ E+PD ++L GGQT LNCGV L K GVL +Y +KVLGT ++++
Sbjct: 482 VYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESI 541
Query: 146 ETSEDRDLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFAN 205
+EDR LF+ L EI+ A S A E+++ AL+AAD +G+PV++RSAYALGGLGSG
Sbjct: 542 MATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICP 601
Query: 206 NAQEMKQLASQSLSLAPQILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGIHTG 265
N + + L++++ ++ QILVEKS+ GWKE+EYEVVRD NC+TVCNMEN D +G+HTG
Sbjct: 602 NRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTG 661
Query: 266 DSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXX 325
DS+V AP+QTLS+ EF MLR +I ++RHLG++GECN+Q+AL P S++Y +IEVN
Sbjct: 662 DSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSR 721
Query: 326 XXXXXXXXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSLDYIVAKIPRWDLSKF 385
TGYPLA+ AAKIALG LPE+ N ++ T A FEPSLDY+V KIPRWDL +F
Sbjct: 722 SSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRF 781
Query: 386 QHVNRSVGSSMKSVGEVMAIGRNFEEAFQKAIRQIDPSFIGFQGSDEFD-------DLDN 438
+ +GSSMKSVGEVMAIGR FEE+FQKA+R PS GF + DL
Sbjct: 782 HGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRK 841
Query: 439 ALSEPTDRRWLAVGQALIHEGYSVEKVHELTKIDSWFLFKCMNIVDMYKDLEQVNDXXXX 498
LSEP+ R A+ +A I + S++++ +LT ID WFL+K +I++M K L+ +N
Sbjct: 842 ELSEPSSTRIYAIAKA-IDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLN-SESM 899
Query: 499 XXXXXXXXXXXGFSDAQIALCLNKGSDSRTSELEVRSYRKSFGIVPFVKRIDTLAAEFPA 558
GFSD QI+ CL +E + R R I P+VK+IDTLAAE+P+
Sbjct: 900 TEETLKRAKEIGFSDKQISKCLG------LTEAQTRELRLKKNIHPWVKQIDTLAAEYPS 953
Query: 559 QTNYLYTTYNATKSDIEFTDNGVLVLGSGVYRIGSSVEFDWCAVNTTKALRKEGKKTIMI 618
TNYLY TYN + D+ F D+G++VLG G Y IGSSVEFDWCAV++ + LR+ GKKT+++
Sbjct: 954 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV 1013
Query: 619 NYNPETVSTDFDEVDRLYFEELSFERVMDIYELENSEGCVISVGGQLPQNIALKLLHNGA 678
N NPETVSTDFDE D+LYFEELS ER++DIY E GC+ISVGGQ+P N+A+ L NG
Sbjct: 1014 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV 1073
Query: 679 HILGTSPEDIDKAENRHKFSTILDSIGVNQPEWSELSSVEEAKVFANQVGYPVLIRPSYV 738
I+GTSP ID+AE+R FS +LD + V Q W ++++ EA FA V YP L+RPSYV
Sbjct: 1074 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV 1133
Query: 739 LSGAAMSVVTGEHELEVKLTTASDVSPDHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAIS 798
LSG+AM+VV E E++ L A+ VS +HPVV++KF+EGA+E+++DAV +G V+ HAIS
Sbjct: 1134 LSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAIS 1193
Query: 799 EHVENAGIHSGDATLVLPPQNLSQNIKDRLKEIADKVAKAWNITGPFNMQIIKDDRDEGV 858
EHVE+AG+HSGDATL+LP Q +SQ +++K+ K+AKA+ I+GPFN+Q + +G
Sbjct: 1194 EHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLV----KGN 1249
Query: 859 SLKVIECNIRASRSFPFVSKVLGVNFIEAAVQAFLSKDVPEP-VNLMDKAY---DYVATK 914
+ VIECN+RASRSFPFVSK LGV+FI+ A + + ++V E + +D DYVA K
Sbjct: 1250 DVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIK 1309
Query: 915 VPQFSFTRLAGADPFLGVEMASTGEVASFGSNALESYWTAIQSTMNFNVPLPPSGILFGG 974
P FS+ RL ADP L EMASTGEVA FG ++ A+ ST +P GIL G
Sbjct: 1310 APMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLST---GFKIPQKGILIGI 1366
Query: 975 DLS--KNYLGEVVKYVAPLGYKLYATNEDTKKYLETFSKGVSVELIEFPKNDKR-----K 1027
S +LG V + + G+KL+AT E T +L + V + +P + +
Sbjct: 1367 QQSFRPRFLG-VAEQLHNEGFKLFAT-EATSDWLN--ANNVPATPVAWPSQEGQNPSLSS 1422
Query: 1028 LRELFQAKDISAVFNLAAKRAESLEDVDYIMRRNAIDFALPLFNEPQTAMLFAKAMSLKI 1087
+R+L + I V NL + + D +Y++RR A+D +PL Q LFA+A+
Sbjct: 1423 IRKLIRDGSIDLVINLPNNNTKFVHD-NYVIRRTAVDSGIPLLTNFQVTKLFAEAV---- 1477
Query: 1088 AEKVKVLESKDV 1099
+K + ++SK +
Sbjct: 1478 -QKSRKVDSKSL 1488
>HsM4503019 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 1500
Score = 994 bits (2571), Expect = 0.0
Identities = 534/1092 (48%), Positives = 729/1092 (65%), Gaps = 46/1092 (4%)
Query: 29 VESVLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIA---TNQTSHSLADE 85
V VL++GSGGLSIGQAGEFDYSGSQA+KA+KE N KT+L+NPNIA TN+ AD
Sbjct: 422 VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADT 481
Query: 86 IYYLPVTPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKTL 145
+Y+LP+TP+++T +I+ E+PD ++L GGQT LNCGV L K GVL +Y +KVLGT ++++
Sbjct: 482 VYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESI 541
Query: 146 ETSEDRDLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFAN 205
+EDR LF+ L EI+ A S A E+++ AL+AAD +G+PV++RSAYALGGLGSG
Sbjct: 542 MATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICP 601
Query: 206 NAQEMKQLASQSLSLAPQILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGIHTG 265
N + + L++++ ++ QILVEKS+ GWKE+EYEVVRD NC+TVCNMEN D +G+HTG
Sbjct: 602 NRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTG 661
Query: 266 DSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXX 325
DS+V AP+QTLS+ EF MLR +I ++RHLG++GECN+Q+AL P S++Y +IEVN
Sbjct: 662 DSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNAKMSP 721
Query: 326 XXXXXXXXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSLDYIVAKIPRWDLSKF 385
TGYPLA+ AAKIALG LP + N ++ T A FEPSLDY+V KIPRWDL +F
Sbjct: 722 NSALASKTTGYPLAFIAAKIALGIPLPGIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRF 781
Query: 386 QHVNRSVGSSMKSVGEVMAIGRNFEEAFQKAIRQIDPSFIGFQGSDEFD-------DLDN 438
+ +GSSMKSVGEVMAIGR FEE+FQKA+R PS GF + DL
Sbjct: 782 HGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRK 841
Query: 439 ALSEPTDRRWLAVGQALIHEGYSVEKVHELTKIDSWFLFKCMNIVDMYKDLEQVNDXXXX 498
LSEP+ R A+ +A I + S++++ +LT ID WFL+K +I++M K L+ +N
Sbjct: 842 ELSEPSSTRIYAIAKA-IDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLN-SESM 899
Query: 499 XXXXXXXXXXXGFSDAQIALCLNKGSDSRTSELEVRSYRKSFGIVPFVKRIDTLAAEFPA 558
GFSD QI+ CL +E + R R I P+VK+IDTLAAE+P+
Sbjct: 900 TEETLKRAKEIGFSDKQISKCLG------LTEAQTRELRLKKNIHPWVKQIDTLAAEYPS 953
Query: 559 QTNYLYTTYNATKSDIEFTDNGVLVLGSGVYRIGSSVEFDWCAVNTTKALRKEGKKTIMI 618
TNYLY TYN + D+ F D+G++VLG G Y IGSSVEFDWCAV++ + LR+ GKKT+++
Sbjct: 954 VTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVV 1013
Query: 619 NYNPETVSTDFDEVDRLYFEELSFERVMDIYELENSEGCVISVGGQLPQNIALKLLHNGA 678
N NPETVSTDFDE D+LYFEELS ER++DIY E GC+ISVGGQ+P N+A+ L NG
Sbjct: 1014 NCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGV 1073
Query: 679 HILGTSPEDIDKAENRHKFSTILDSIGVNQPEWSELSSVEEAKVFANQVGYPVLIRPSYV 738
I+GTSP ID+AE+R FS +LD + V Q W ++++ EA FA V YP L+RPSYV
Sbjct: 1074 KIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYV 1133
Query: 739 LSGAAMSVVTGEHELEVKLTTASDVSPDHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAIS 798
LSG+AM+VV E E++ L A+ VS PVV++KF+EGA+E+++DAV +G V+ HAIS
Sbjct: 1134 LSGSAMNVVFSEDEMKKFLEEATRVSQATPVVLTKFVEGAREVEMDAVGKDGRVISHAIS 1193
Query: 799 EHVENAGIHSGDATLVLPPQNLSQNIKDRLKEIADKVAKAWNITGPFNMQIIKDDRDEGV 858
EHVE+AG+HS +ATL+LP Q +SQ +++K+ K+AKA+ I+GPFN+Q + +G
Sbjct: 1194 EHVEDAGVHSENATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLV----KGN 1249
Query: 859 SLKVIECNIRASRSFPFVSKVLGVNFIEAAVQAFLSKDVPEP-VNLMDK---AYDYVATK 914
+ V ECN+RASRSFP VSK LGV+FI+ A + + ++V E + +D DYVA K
Sbjct: 1250 DVLVNECNLRASRSFPSVSKTLGVDFIDVATKVLIGENVDEKHLPTLDHPIIPVDYVAIK 1309
Query: 915 VPQFSFTRLAGADPFLGVEMASTGEVASFGSNALESYWTAIQSTMNFNVPLPPSGILFGG 974
P FS+ RL ADP L EMASTGEVA FG ++ A+ ST +P GIL G
Sbjct: 1310 APMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLST---GFKIPQKGILIGI 1366
Query: 975 DLS--KNYLGEVVKYVAPLGYKLYATNEDTKKYLETFSKGVSVELIEFPKNDKR-----K 1027
S +LG V + + G+KL+AT E T +L + V + +P + +
Sbjct: 1367 QQSFRPRFLG-VAEQLHNEGFKLFAT-EATSDWLN--ANNVPANPVAWPSQEGQNPSLSS 1422
Query: 1028 LRELFQAKDISAVFNLAAKRAESLEDVDYIMRRNAIDFALPLFNEPQTAMLFAKAMSLKI 1087
+R+L + I V NL + + D +Y++RR A+D +PL Q LFA+A+
Sbjct: 1423 IRKLIRDGSIDLVINLPNNNTKFVHD-NYVIRRTAVDSGIPLLTNFQVTKLFAEAV---- 1477
Query: 1088 AEKVKVLESKDV 1099
+K + ++SK +
Sbjct: 1478 -QKSRKVDSKSL 1488
>At1g29900 [R] KOG0370 Multifunctional pyrimidine synthesis protein CAD
(includes carbamoyl-phophate synthetase aspartate
transcarbamylase and glutamine amidotransferase)
Length = 956
Score = 324 bits (831), Expect = 4e-88
Identities = 164/366 (44%), Positives = 239/366 (64%), Gaps = 7/366 (1%)
Query: 18 TDEYNPQLV---EGVESVLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIA 74
T ++P++V ++ ++++G+G + IGQA EFDYSG+QA KAL+E + IL+N N A
Sbjct: 84 TKPFSPEIVGKRTDLKKIMILGAGPIVIGQACEFDYSGTQACKALREEGYEVILINSNPA 143
Query: 75 TNQTSHSLADEIYYLPVTPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYN 134
T T A+ Y P+TPE + +IE+ERPDA+L T GGQT LN VAL ++G L KY
Sbjct: 144 TIMTDPETANRTYIAPMTPELVEQVIEKERPDALLPTMGGQTALNLAVALAESGALEKYG 203
Query: 135 IKVLGTPIKTLETSEDRDLFAQALKEIDIPTAESIACETVDAALEAADIVG-FPVIVRSA 193
++++G + ++ +EDR+LF A+K I + T S T+D + A+ +G FP+I+R A
Sbjct: 204 VELIGAKLGAIKKAEDRELFKDAMKNIGLKTPPSGIGTTLDECFDIAEKIGEFPLIIRPA 263
Query: 194 YALGGLGSGFANNAQEMKQLASQSL--SLAPQILVEKSLKGWKEVEYEVVRDRVGNCITV 251
+ LGG G G A N +E + + L S Q+LVEKSL GWKE E EV+RD N + +
Sbjct: 264 FTLGGTGGGIAYNKEEFESICKSGLAASATSQVLVEKSLLGWKEYELEVMRDLADNVVII 323
Query: 252 CNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGV-IGECNVQYALSPD 310
C++EN DP+G+HTGDSI AP+QTL+D E+ LR +I IIR +GV G NVQ+A++P
Sbjct: 324 CSIENIDPMGVHTGDSITVAPAQTLTDREYQRLRDYSIAIIREIGVECGGSNVQFAVNPV 383
Query: 311 SLDYRVIEVNXXXXXXXXXXXXXTGYPLAYTAAKIALGYTLPELPNPITKTTVANFEPSL 370
+ +IE+N TG+P+A AAK+++GYTL ++PN IT+ T A+FEPS+
Sbjct: 384 DGEVMIIEMNPRVSRSSALASKATGFPIAKMAAKLSVGYTLDQIPNDITRKTPASFEPSI 443
Query: 371 DYIVAK 376
DY+V K
Sbjct: 444 DYVVTK 449
Score = 254 bits (649), Expect = 5e-67
Identities = 167/502 (33%), Positives = 261/502 (51%), Gaps = 24/502 (4%)
Query: 612 GKKTIMINYNPETVSTDFDEVDRLYFEELSFERVMDIYELENSEGCVISVGGQLPQNIAL 671
G +TIM+N NPETVSTD+D DRLYFE L+ E V+++ +LE +G ++ GGQ P +AL
Sbjct: 452 GYETIMLNSNPETVSTDYDTSDRLYFEPLTIEDVLNVIDLEKPDGIIVQFGGQTPLKLAL 511
Query: 672 KLLH----------NGA---HILGTSPEDIDKAENRHKFSTILDSIGVNQPEWSELSSVE 718
+ H +GA I GTSP+ ID AE+R +F+ ILD + + QP+ S
Sbjct: 512 PIKHYLDKHMPMSLSGAGPVRIWGTSPDSIDAAEDRERFNAILDELKIEQPKGGIAKSEA 571
Query: 719 EAKVFANQVGYPVLIRPSYVLSGAAMSVVTGEHELEVKLTTASDVSPDHPVVMSKFIEGA 778
+A A +VGYPV++RPSYVL G AM +V + L L A V P+ PV++ K++ A
Sbjct: 572 DALAIAKEVGYPVVVRPSYVLGGRAMEIVYDDSRLITYLENAVQVDPERPVLVDKYLSDA 631
Query: 779 QEIDVDAVAHN-GMVLVHAISEHVENAGIHSGDATLVLPPQNLSQNIKDRLKEIADKVAK 837
EIDVD + + G V++ I EH+E AG+HSGD+ +LP Q + + ++ K+AK
Sbjct: 632 IEIDVDTLTDSYGNVVIGGIMEHIEQAGVHSGDSACMLPTQTIPASCLQTIRTWTTKLAK 691
Query: 838 AWNITGPFNMQIIKDDRDEGVSLKVIECNIRASRSFPFVSKVLGVNFIEAAVQAFLSKDV 897
N+ G N Q + + ++E N RASR+ PFVSK +G + A K +
Sbjct: 692 KLNVCGLMNCQYAITTSGD---VFLLEANPRASRTVPFVSKAIGHPLAKYAALVMSGKSL 748
Query: 898 PEPVNLMDKAYDYVATKVPQFSFTRLAGADPFLGVEMASTGEVASFGSNALESYWTAIQS 957
+ + +V+ K F F + G D LG EM STGEV S S+ S + Q
Sbjct: 749 KDLNFEKEVIPKHVSVKEAVFPFEKFQGCDVILGPEMRSTGEVMSI-SSEFSSAFAMAQI 807
Query: 958 TMNFNVPLPPSGILFGGDLSKNYLGEVVKYVAPLGYKLYATNEDTKKYLETFSKGVSVEL 1017
+PL + L D++K +L ++ LG+K+ AT+ T +LE KG+ VE
Sbjct: 808 AAGQKLPLSGTVFLSLNDMTKPHLEKIAVSFLELGFKIVATS-GTAHFLEL--KGIPVER 864
Query: 1018 IEFPKNDKRKLRELFQAKDISAVFNLAAKRAESLEDVD-YIMRRNAIDFALPLFNEPQTA 1076
+ + ++ I + L ++L+ D +R+ A+ + +P+ A
Sbjct: 865 VLKLHEGRPHAADMVANGQIHLM--LITSSGDALDQKDGRQLRQMALAYKVPVITTVAGA 922
Query: 1077 MLFAKAMSLKIAEKVKVLESKD 1098
+ A+ + + +K+ +D
Sbjct: 923 LATAEGIKSLKSSAIKMTALQD 944
Score = 160 bits (405), Expect = 1e-38
Identities = 109/368 (29%), Positives = 181/368 (48%), Gaps = 22/368 (5%)
Query: 60 KEANKKTILVNPNIATNQTSHSLADEIYYLPVTPEYITYIIERERPDAILLTFGGQTGLN 119
K+A +TI++N N T T + +D +Y+ P+T E + +I+ E+PD I++ FGGQT L
Sbjct: 449 KDAGYETIMLNSNPETVSTDYDTSDRLYFEPLTIEDVLNVIDLEKPDGIIVQFGGQTPLK 508
Query: 120 CGVA----LDKAGVLAKYN---IKVLGTPIKTLETSEDRDLFAQALKEIDIPTAESIACE 172
+ LDK ++ +++ GT +++ +EDR+ F L E+ I + +
Sbjct: 509 LALPIKHYLDKHMPMSLSGAGPVRIWGTSPDSIDAAEDRERFNAILDELKIEQPKGGIAK 568
Query: 173 TVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLAPQ--ILVEKSL 230
+ AL A VG+PV+VR +Y LGG + + ++ + P+ +LV+K L
Sbjct: 569 SEADALAIAKEVGYPVVVRPSYVLGGRAMEIVYDDSRLITYLENAVQVDPERPVLVDKYL 628
Query: 231 KGWKEVEYEVVRDRVGNCITVCNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIK 290
E++ + + D GN + ME+ + G+H+GDS P+QT+ +R+ K
Sbjct: 629 SDAIEIDVDTLTDSYGNVVIGGIMEHIEQAGVHSGDSACMLPTQTIPASCLQTIRTWTTK 688
Query: 291 IIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXXXXXXXTGYPLAYTAAKIALGYT 350
+ + L V G N QYA++ S D ++E N G+PLA AA + G +
Sbjct: 689 LAKKLNVCGLMNCQYAIT-TSGDVFLLEANPRASRTVPFVSKAIGHPLAKYAALVMSGKS 747
Query: 351 LPELPNPITKTTVANFEPSL--DYIVAKIPRWDLSKFQHVNRSVGSSMKSVGEVMAIGRN 408
L +L NFE + ++ K + KFQ + +G M+S GEVM+I
Sbjct: 748 LKDL----------NFEKEVIPKHVSVKEAVFPFEKFQGCDVILGPEMRSTGEVMSISSE 797
Query: 409 FEEAFQKA 416
F AF A
Sbjct: 798 FSSAFAMA 805
Score = 141 bits (355), Expect = 7e-33
Identities = 97/352 (27%), Positives = 175/352 (49%), Gaps = 21/352 (5%)
Query: 581 VLVLGSGVYRIGSSVEFDWCAVNTTKALRKEGKKTIMINYNPETVSTDFDEVDRLYFEEL 640
+++LG+G IG + EFD+ KALR+EG + I+IN NP T+ TD + +R Y +
Sbjct: 101 IMILGAGPIVIGQACEFDYSGTQACKALREEGYEVILINSNPATIMTDPETANRTYIAPM 160
Query: 641 SFERVMDIYELENSEGCVISVGGQLPQNIALKLLHNGA------HILGTSPEDIDKAENR 694
+ E V + E E + + ++GGQ N+A+ L +GA ++G I KAE+R
Sbjct: 161 TPELVEQVIEKERPDALLPTMGGQTALNLAVALAESGALEKYGVELIGAKLGAIKKAEDR 220
Query: 695 HKFSTILDSIGVNQPEWSELSSVEEAKVFANQVG-YPVLIRPSYVLSGAAMSVVTGEHEL 753
F + +IG+ P ++++E A ++G +P++IRP++ L G + + E
Sbjct: 221 ELFKDAMKNIGLKTPPSGIGTTLDECFDIAEKIGEFPLIIRPAFTLGGTGGGIAYNKEEF 280
Query: 754 EVKLTTASDVSPDHPVVMSKFIEGAQEIDVDAVAH--NGMVLVHAISEHVENAGIHSGDA 811
E + S V++ K + G +E +++ + + +V++ +I E+++ G+H+GD+
Sbjct: 281 ESICKSGLAASATSQVLVEKSLLGWKEYELEVMRDLADNVVIICSI-ENIDPMGVHTGDS 339
Query: 812 TLVLPPQNLSQNIKDRLKEIADKVAKAWNI-TGPFNMQIIKDDRDEGVSLKVIECNIRAS 870
V P Q L+ RL++ + + + + G N+Q + D V +IE N R S
Sbjct: 340 ITVAPAQTLTDREYQRLRDYSIAIIREIGVECGGSNVQFAVNPVDGEV--MIIEMNPRVS 397
Query: 871 RSFPFVSKVLGVNFIEAAVQ---AFLSKDVPEPVN-----LMDKAYDYVATK 914
RS SK G + A + + +P + + + DYV TK
Sbjct: 398 RSSALASKATGFPIAKMAAKLSVGYTLDQIPNDITRKTPASFEPSIDYVVTK 449
>7303838 [C] KOG0369 Pyruvate carboxylase
Length = 1181
Score = 63.5 bits (153), Expect = 2e-09
Identities = 78/356 (21%), Positives = 141/356 (38%), Gaps = 49/356 (13%)
Query: 20 EYNPQLVEGVESVLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIATNQTS 79
EY P + SVLV G ++I + +A E K++ V
Sbjct: 35 EYKP-----IRSVLVANRGEIAI-----------RVFRACTELGIKSVAVYSEQDKMHMH 78
Query: 80 HSLADEIYY----LPVTPEYITY-----IIERERPDAILLTFGGQTGLNCGVALDKAGVL 130
ADE Y LP Y+ + + DA+ +G + + D A +
Sbjct: 79 RQKADESYIVGKGLPPVEAYLNIPELIRVCKENDVDAVHPGYGFLSERS-----DFAQAV 133
Query: 131 AKYNIKVLGTPIKTLETSEDRDLFAQALKEIDIPTAESI--ACETVDAALEAADIVGFPV 188
++ +G + ++ D+ A E +P T + ALE G PV
Sbjct: 134 IDAGLRFIGPSPEVVQKMGDKVAARVAAIEAGVPIVPGTDGPVTTKEEALEFCKKHGLPV 193
Query: 189 IVRSAYALGGLGSGFANNAQEMKQLASQSLSLAPQ------ILVEKSLKGWKEVEYEVVR 242
I ++AY GG G +++++ ++ S A + +EK ++ + +E +++
Sbjct: 194 IFKAAYGGGGRGMRVVRKMEDVEESFQRASSEAKAAFGNGAMFIEKFIERPRHIEVQLLG 253
Query: 243 DRVGNCITV----CNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVI 298
D+ GN + + C+++ + AP+ L E + AA+++ RH+G
Sbjct: 254 DKAGNVVHLYERDCSVQR------RHQKVVEIAPAPRLPIEIRDKMTEAAVRLARHVGYE 307
Query: 299 GECNVQYALSPDSLDYRVIEVNXXXXXXXXXXXXXTGYPLAYTAAKIALGYTLPEL 354
V++ L +S ++ IEVN TG L + ++A G TLPEL
Sbjct: 308 NAGTVEF-LCDESGNFYFIEVNARLQVEHTVTEEITGIDLVQSQIRVAEGMTLPEL 362
Score = 55.1 bits (131), Expect = 6e-07
Identities = 67/322 (20%), Positives = 127/322 (38%), Gaps = 20/322 (6%)
Query: 601 AVNTTKALRKEGKKTIMINYNPETVSTDFDEVDRLYFEELSF---ERVMDIYEL-----E 652
A+ +A + G K++ + + + + D Y E ++I EL E
Sbjct: 51 AIRVFRACTELGIKSVAVYSEQDKMHMHRQKADESYIVGKGLPPVEAYLNIPELIRVCKE 110
Query: 653 NSEGCVISVGGQLPQ--NIALKLLHNGAHILGTSPEDIDKAENR--HKFSTILDSIGVNQ 708
N V G L + + A ++ G +G SPE + K ++ + + I + +
Sbjct: 111 NDVDAVHPGYGFLSERSDFAQAVIDAGLRFIGPSPEVVQKMGDKVAARVAAIEAGVPIVP 170
Query: 709 PEWSELSSVEEAKVFANQVGYPVLIRPSYVLSGAAMSVVTGEHELEVKLTTASDVSP--- 765
+++ EEA F + G PV+ + +Y G M VV ++E AS +
Sbjct: 171 GTDGPVTTKEEALEFCKKHGLPVIFKAAYGGGGRGMRVVRKMEDVEESFQRASSEAKAAF 230
Query: 766 -DHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAISEHVENAGIHSGDATLVLPPQNLSQNI 824
+ + + KFIE + I+V + +VH H + P L I
Sbjct: 231 GNGAMFIEKFIERPRHIEVQLLGDKAGNVVHLYERDCSVQRRHQ-KVVEIAPAPRLPIEI 289
Query: 825 KDRLKEIADKVAKAWNITGPFNMQIIKDDRDEGVSLKVIECNIRASRSFPFVSKVLGVNF 884
+D++ E A ++A+ G N ++ DE + IE N R ++ G++
Sbjct: 290 RDKMTEAAVRLARH---VGYENAGTVEFLCDESGNFYFIEVNARLQVEHTVTEEITGIDL 346
Query: 885 IEAAVQAFLSKDVPEPVNLMDK 906
+++ ++ +PE DK
Sbjct: 347 VQSQIRVAEGMTLPELGYTQDK 368
>CE09072 [C] KOG0369 Pyruvate carboxylase
Length = 1175
Score = 63.2 bits (152), Expect = 2e-09
Identities = 75/322 (23%), Positives = 129/322 (39%), Gaps = 33/322 (10%)
Query: 54 QAIKALKEANKKTILVNPNIATNQTSHSLADEIYY----LPVTPEYITY--IIE---RER 104
+ +AL E NK ++ + N ADE Y LP Y+T IIE +
Sbjct: 46 RVFRALTELNKTSVAIYAEQDKNSMHRLKADEAYLVGKGLPPVAAYLTIDQIIETALKHN 105
Query: 105 PDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKTLETSEDRDLFAQALKEIDIP 164
DAI +G + + D A I +G + D+ QA E +
Sbjct: 106 IDAIHPGYGFLSERS-----DFAAACQNAGIVFIGPSPDVMARMGDKVAARQAAIEAGVQ 160
Query: 165 TAESIA--CETVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLAP 222
T D A+E A G P+I+++AY GG G + +E+++ +S S A
Sbjct: 161 VVPGTPGPITTADEAVEFAKQYGTPIILKAAYGGGGRGIRRVDKLEEVEEAFRRSYSEAQ 220
Query: 223 ------QILVEKSLKGWKEVEYEVVRDRVGNCITV----CNMENFDPLGIHTGDSIVFAP 272
+ VEK ++ + +E +++ D GN + + C+++ + AP
Sbjct: 221 AAFGDGSLFVEKFVERPRHIEVQLLGDHHGNIVHLYERDCSVQR------RHQKVVEIAP 274
Query: 273 SQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXXXXXX 332
+ L + + + A+++ RH+G V++ + +Y IEVN
Sbjct: 275 APALPEGVREKILADALRLARHVGYQNAGTVEFLVDQKG-NYYFIEVNARLQVEHTVTEE 333
Query: 333 XTGYPLAYTAAKIALGYTLPEL 354
TG L +IA G +L +L
Sbjct: 334 ITGVDLVQAQIRIAEGKSLDDL 355
>Hs13518228 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 725
Score = 61.6 bits (148), Expect = 7e-09
Identities = 73/352 (20%), Positives = 142/352 (39%), Gaps = 39/352 (11%)
Query: 601 AVNTTKALRKEGKKTIMINYNPETVSTDFDEVDRLYF--------EELSFERVMDIYELE 652
A + +K G +T+ + + S D D Y LS E+++ + +
Sbjct: 61 ACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTS 120
Query: 653 NSE----GCVISVGGQLPQNIALKLL--HNGAHILGTSPEDIDKAENRHKFSTILDSIGV 706
++ GC G L +N+ L G +G P I + +I+ + GV
Sbjct: 121 AAQAIHPGC-----GFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGV 175
Query: 707 NQPEW--SELSSVEEAKVFANQVGYPVLIRPSYVLSGAAMSVVTGEHELEVKLTTASDVS 764
E E S + K A ++GYPV+I+ G M +V E E + +L +A +
Sbjct: 176 PVVEGYHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREA 235
Query: 765 P----DHPVVMSKFIEGAQEIDVDAVA-HNGMVLVHAISEHVENAGIHSGDATLV--LPP 817
D +++ KF++ + ++V H+G +A+ + + ++ P
Sbjct: 236 KKSFNDDAMLIEKFVDTPRHVEVQVFGDHHG----NAVYLFERDCSVQRRHQKIIEEAPA 291
Query: 818 QNLSQNIKDRLKEIADKVAKAWNITGPFNMQIIKDDRDEGVSLKVIECNIRASRSFPFVS 877
+ ++ +L E A + AKA N G ++ I D + + +E N R P
Sbjct: 292 PGIKSEVRKKLGEAAVRAAKAVNYVGAGTVEFIMDSKH---NFCFMEMNTRLQVEHPVTE 348
Query: 878 KVLGVNFIEAAVQAFLSKDVP---EPVNLMDKAYD-YVATKVPQFSFTRLAG 925
+ G + +E ++ + +P E + L A++ + + P +F +AG
Sbjct: 349 MITGTDLVEWQLRIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAG 400
>YGL062w [C] KOG0369 Pyruvate carboxylase
Length = 1178
Score = 59.7 bits (143), Expect = 3e-08
Identities = 55/248 (22%), Positives = 102/248 (40%), Gaps = 11/248 (4%)
Query: 127 AGVLAKYNIKVLGTPIKTLETSEDRDLFAQALKEIDIPTAESIA--CETVDAALEAADIV 184
A + K I +G P + +++ D+ + ++PT ETV+ AL+ +
Sbjct: 112 ADKVVKAGITWIGPPAEVIDSVGDKVSARNLAAKANVPTVPGTPGPIETVEEALDFVNEY 171
Query: 185 GFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLA------PQILVEKSLKGWKEVEY 238
G+PVI+++A+ GG G ++ ++ S A VE+ L K +E
Sbjct: 172 GYPVIIKAAFGGGGRGMRVVREGDDVADAFQRATSEARTAFGNGTCFVERFLDKPKHIEV 231
Query: 239 EVVRDRVGNCITVCNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVI 298
+++ D GN + + E + + AP++TL E + + A+K+ + G
Sbjct: 232 QLLADNHGNVVHL--FERDCSVQRRHQKVVEVAPAKTLPREVRDAILTDAVKLAKECGYR 289
Query: 299 GECNVQYALSPDSLDYRVIEVNXXXXXXXXXXXXXTGYPLAYTAAKIALGYTLPELPNPI 358
++ + + Y IE+N TG + +IA G +LP+L
Sbjct: 290 NAGTAEFLVDNQNRHY-FIEINPRIQVEHTITEEITGIDIVAAQIQIAAGASLPQLGLFQ 348
Query: 359 TKTTVANF 366
K T F
Sbjct: 349 DKITTRGF 356
Score = 52.4 bits (124), Expect = 4e-06
Identities = 43/197 (21%), Positives = 82/197 (40%), Gaps = 8/197 (4%)
Query: 714 LSSVEEAKVFANQVGYPVLIRPSYVLSGAAMSVVTGEHEL----EVKLTTASDVSPDHPV 769
+ +VEEA F N+ GYPV+I+ ++ G M VV ++ + + A +
Sbjct: 158 IETVEEALDFVNEYGYPVIIKAAFGGGGRGMRVVREGDDVADAFQRATSEARTAFGNGTC 217
Query: 770 VMSKFIEGAQEIDVDAVAHNGMVLVHAISEHVENAGIHSGDATLVLPPQNLSQNIKDRLK 829
+ +F++ + I+V +A N +VH H V P + L + ++D +
Sbjct: 218 FVERFLDKPKHIEVQLLADNHGNVVHLFERDCSVQRRHQ-KVVEVAPAKTLPREVRDAIL 276
Query: 830 EIADKVAKAWNITGPFNMQIIKDDRDEGVSLKVIECNIRASRSFPFVSKVLGVNFIEAAV 889
A K+AK + + D+++ IE N R ++ G++ + A +
Sbjct: 277 TDAVKLAKECGYRNAGTAEFLVDNQNRHY---FIEINPRIQVEHTITEEITGIDIVAAQI 333
Query: 890 QAFLSKDVPEPVNLMDK 906
Q +P+ DK
Sbjct: 334 QIAAGASLPQLGLFQDK 350
>YMR207c [I] KOG0368 Acetyl-CoA carboxylase
Length = 2123
Score = 58.5 bits (140), Expect = 6e-08
Identities = 45/184 (24%), Positives = 83/184 (44%), Gaps = 12/184 (6%)
Query: 171 CETVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLAP--QILVEK 228
C + + ALE A ++GFPV+++++ GG G +N + L Q+++ P + V K
Sbjct: 158 CSSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGSPMFVMK 217
Query: 229 SLKGWKEVEYEVVRDRVGNCITV----CNMENFDPLGIHTGDSIVFAPSQTLSDEEFHML 284
+ + +E +++ D+ G IT+ C+++ I AP E F +
Sbjct: 218 VVTDARHLEVQLLADQYGTNITLFGRDCSIQR------RHQKIIEEAPVTITKPETFQRM 271
Query: 285 RSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXXXXXXXTGYPLAYTAAK 344
AAI++ +G + V+Y SP + +E+N +G L T +
Sbjct: 272 ERAAIRLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVNLPATQLQ 331
Query: 345 IALG 348
IA+G
Sbjct: 332 IAMG 335
>YBR208c_2 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 1200
Score = 58.5 bits (140), Expect = 6e-08
Identities = 72/314 (22%), Positives = 130/314 (40%), Gaps = 20/314 (6%)
Query: 601 AVNTTKALRKEGKKTIMINYNPETVS---TDFDEVDRLYFEE-----LSFERVMDIYELE 652
AV K L+K G +++ + +P+ S TD D L+ L +++D +
Sbjct: 10 AVRIIKTLKKLGIRSVAVYSDPDKYSQHVTDADVSVPLHGTTAAQTYLDMNKIIDAAKQT 69
Query: 653 NSEGCVISVGGQLPQNIALKLLHNGAHI--LGTSPEDIDKAENRHKFSTILDSIGVNQPE 710
N++ +I G L +N A I +G S + I +H I GV
Sbjct: 70 NAQA-IIPGYGFLSENADFSDACTSAGITFVGPSGDIIRGLGLKHSARQIAQKAGVPLVP 128
Query: 711 WSEL-SSVEEAKVFANQVGYPVLIRPSYVLSGAAMSVVTGEHELEVKLTTASDVSP---- 765
S L +SVEEAK A ++ YPV+++ + G + V E ++E T
Sbjct: 129 GSLLITSVEEAKKVAAELEYPVMVKSTAGGGGIGLQKVDSEEDIEHIFETVKHQGETFFG 188
Query: 766 DHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAISEHVENAGIHSGDATLVLPPQNLSQNIK 825
D V + +FIE A+ ++V + +G A+ E + + P NL + +
Sbjct: 189 DAGVFLERFIENARHVEVQLMG-DGFGKAIALGERDCSLQRRNQKVIEETPAPNLPEKTR 247
Query: 826 DRLKEIADKVAKAWNITGPFNMQIIKDDRDEGVSLKVIECNIRASRSFPFVSKVLGVNFI 885
L++ A+ + N ++ I D++ + +E N R P V G++ +
Sbjct: 248 LALRKAAESLGSLLNYKCAGTVEFIYDEKKD--EFYFLEVNTRLQVEHPITEMVTGLDLV 305
Query: 886 EAAVQAFLSKDVPE 899
E ++ + D P+
Sbjct: 306 EWMIR-IAANDAPD 318
>YBR218c [C] KOG0369 Pyruvate carboxylase
Length = 1180
Score = 56.2 bits (134), Expect = 3e-07
Identities = 55/248 (22%), Positives = 99/248 (39%), Gaps = 11/248 (4%)
Query: 127 AGVLAKYNIKVLGTPIKTLETSEDRDLFAQALKEIDIPTAESIA--CETVDAALEAADIV 184
A + K I +G P + +++ D+ ++PT ETV AL+ +
Sbjct: 113 ADKVVKAGITWIGPPAEVIDSVGDKVSARHLAARANVPTVPGTPGPIETVQEALDFVNEY 172
Query: 185 GFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLA------PQILVEKSLKGWKEVEY 238
G+PVI+++A+ GG G ++ ++ S A VE+ L K +E
Sbjct: 173 GYPVIIKAAFGGGGRGMRVVREGDDVADAFQRATSEARTAFGNGTCFVERFLDKPKHIEV 232
Query: 239 EVVRDRVGNCITVCNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVI 298
+++ D GN + + E + + AP++TL E + + A+K+ + G
Sbjct: 233 QLLADNHGNVVHL--FERDCSVQRRHQKVVEVAPAKTLPREVRDAILTDAVKLAKVCGYR 290
Query: 299 GECNVQYALSPDSLDYRVIEVNXXXXXXXXXXXXXTGYPLAYTAAKIALGYTLPELPNPI 358
++ + + Y IE+N TG + +IA G TL +L
Sbjct: 291 NAGTAEFLVDNQNRHY-FIEINPRIQVEHTITEEITGIDIVSAQIQIAAGATLTQLGLLQ 349
Query: 359 TKTTVANF 366
K T F
Sbjct: 350 DKITTRGF 357
>Hs4826637 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2346
Score = 55.5 bits (132), Expect = 5e-07
Identities = 41/153 (26%), Positives = 74/153 (47%), Gaps = 13/153 (8%)
Query: 174 VDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLAP--QILVEKSLK 231
VD L+AA+ VG+PV+++++ GG G NNA + L Q + P I V + K
Sbjct: 294 VDDGLKAAEKVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAK 353
Query: 232 GWKEVEYEVVRDRVGNCITV----CNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSA 287
+ +E +++ D+ GN I++ C+++ I AP+ + F +
Sbjct: 354 QSRHLEVQILADQYGNAISLFGRDCSVQR------RHQKIIEEAPATIATPAVFEHMEQC 407
Query: 288 AIKIIRHLGVIGECNVQYALSPDSLDYRVIEVN 320
A+K+ + +G + V+Y S D Y +E+N
Sbjct: 408 AVKLAKMVGYVSAGTVEYLYSQDGSFY-FLELN 439
>Hs4505627 [C] KOG0369 Pyruvate carboxylase
Length = 1178
Score = 55.1 bits (131), Expect = 6e-07
Identities = 65/315 (20%), Positives = 124/315 (38%), Gaps = 20/315 (6%)
Query: 601 AVNTTKALRKEGKKTIMINYNPETVSTDFDEVDRLYF------EELSFERVMDIYEL--E 652
A+ +A + G +T+ I +T + D Y ++ + DI ++ E
Sbjct: 49 AIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKE 108
Query: 653 NSEGCVISVGGQLPQ--NIALKLLHNGAHILGTSPEDIDKAENRHKFSTILDSIGVNQPE 710
N+ V G L + + A G +G SPE + K ++ + I + GV
Sbjct: 109 NNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVP 168
Query: 711 WSE--LSSVEEAKVFANQVGYPVLIRPSYVLSGAAMSVVTGEHELEVKLTTASDVS---- 764
++ ++S+ EA F+N G+P++ + +Y G M VV ELE T A +
Sbjct: 169 GTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAF 228
Query: 765 PDHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAISEHVENAGIHSGDATLVLPPQNLSQNI 824
+ + + KFIE + I+V + ++H H + P +L +
Sbjct: 229 GNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQ-KVVEIAPAAHLDPQL 287
Query: 825 KDRLKEIADKVAKAWNITGPFNMQIIKDDRDEGVSLKVIECNIRASRSFPFVSKVLGVNF 884
+ RL + K+AK ++ + D + IE N R ++ V+
Sbjct: 288 RTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHY---FIEVNSRLQVEHTVTEEITDVDL 344
Query: 885 IEAAVQAFLSKDVPE 899
+ A + + +P+
Sbjct: 345 VHAQIHVSEGRSLPD 359
>7302098 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 684
Score = 55.1 bits (131), Expect = 6e-07
Identities = 42/190 (22%), Positives = 85/190 (44%), Gaps = 16/190 (8%)
Query: 181 ADIVGFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLAPQ------ILVEKSLKGWK 234
AD +GFP+++++ GG G A + + + + + + +L+E+ ++ +
Sbjct: 173 ADKIGFPLMIKAVRGGGGKGMRIAEKPDDFLTALNSARTESEKSFGDSSVLLERYVRSPR 232
Query: 235 EVEYEVVRDRVGNCITV----CNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIK 290
VE +V D+ G+ + + C+++ I AP+ LS++ L AA++
Sbjct: 233 HVEVQVFADQYGDAVYLWERDCSVQRRHQKIIEE------APAPGLSEDLRRELGEAAVR 286
Query: 291 IIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXXXXXXXTGYPLAYTAAKIALGYT 350
+ +G +G V++ L + L + +E+N TG L +IA G
Sbjct: 287 AAKAVGYVGAGTVEFILDKEDLSFHFMEMNTRLQVEHPITEMITGTDLVEWQIRIAAGEP 346
Query: 351 LPELPNPITK 360
LP + IT+
Sbjct: 347 LPLKQSEITR 356
>SPBC17G9.11c [C] KOG0369 Pyruvate carboxylase
Length = 1185
Score = 53.9 bits (128), Expect = 1e-06
Identities = 58/254 (22%), Positives = 99/254 (38%), Gaps = 16/254 (6%)
Query: 663 GQLPQN--IALKLLHNGAHILGTSPEDIDKAENRHKFSTILDSIGVNQPEWSE--LSSVE 718
G L +N A K+ G +G SPE ID ++ K I GV + + E
Sbjct: 117 GFLSENAEFARKVNEAGMQFVGPSPEVIDSLGDKTKARAIAIRCGVPVVPGTPGPVEHYE 176
Query: 719 EAKVFANQVGYPVLIRPSYVLSGAAMSVVTGEHELEVKLTTASDVS----PDHPVVMSKF 774
EA+ F + G PV+I+ + G M VV L+ A + D V + +F
Sbjct: 177 EAEAFVKEYGLPVIIKAAMGGGGRGMRVVRSADTLKESFERARSEALASFGDGTVFIERF 236
Query: 775 IEGAQEIDVDAVAHNGMVLVHAISEHVENAGIHSGDATLV--LPPQNLSQNIKDRLKEIA 832
++ + I++ +A ++H H + + +V P ++L I+ L + A
Sbjct: 237 LDKPKHIEIQLMADKAGNVIHL---HERDCSVQRRHQKVVEIAPAKDLDPKIRQALYDDA 293
Query: 833 DKVAKAWNITGPFNMQIIKDDRDEGVSLKVIECNIRASRSFPFVSKVLGVNFIEAAVQAF 892
K+AK + + D + IE N R ++ GV+ + A +
Sbjct: 294 IKIAKEVKYCNAGTAEFLLDQKGRHY---FIEINPRIQVEHTITEEITGVDIVSAQLHVA 350
Query: 893 LSKDVPEPVNLMDK 906
+PE DK
Sbjct: 351 AGFTLPEIGLTQDK 364
>At1g36180 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2359
Score = 53.5 bits (127), Expect = 2e-06
Identities = 37/154 (24%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 173 TVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLAP--QILVEKSL 230
T + A+ + +VG+P ++++++ GG G +N E++ L Q P I + K
Sbjct: 309 TTEEAIASCQVVGYPAMIKASWGGGGKGIRKVHNDDEVRALFKQVQGEVPGSPIFIMKVA 368
Query: 231 KGWKEVEYEVVRDRVGNCITV----CNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRS 286
+ +E +++ D+ GN + C+++ I G I AP +T+ L
Sbjct: 369 SQSRHLEAQLLCDQYGNVAALHSRDCSVQRRHQKIIEEGP-ITVAPQETIKK-----LEQ 422
Query: 287 AAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVN 320
AA ++ + + +G V+Y S D+ +Y +E+N
Sbjct: 423 AARRLAKSVNYVGAATVEYLYSMDTGEYYFLELN 456
>7304119 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2348
Score = 53.5 bits (127), Expect = 2e-06
Identities = 39/153 (25%), Positives = 74/153 (47%), Gaps = 13/153 (8%)
Query: 174 VDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLAP--QILVEKSLK 231
V+ L A + +GFPV+++++ GG G + +E L Q + P I V K +
Sbjct: 297 VEQGLAAVNKIGFPVMIKASEGGGGKGIRRVDTTEEFPGLFRQVQAEVPGSPIFVMKLAR 356
Query: 232 GWKEVEYEVVRDRVGNCITV----CNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSA 287
G + +E +++ D+ GN I++ C+++ I +IV P E F + A
Sbjct: 357 GARHLEVQLLADQYGNAISLFGRDCSIQRRHQKIIEEAPAIVAQP------EVFEDMEKA 410
Query: 288 AIKIIRHLGVIGECNVQYALSPDSLDYRVIEVN 320
A+++ + +G + V+Y P+ Y +E+N
Sbjct: 411 AVRLAKMVGYVSAGTVEYLYDPEG-RYFFLELN 442
>At5g35360 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 537
Score = 53.1 bits (126), Expect = 2e-06
Identities = 64/295 (21%), Positives = 119/295 (39%), Gaps = 32/295 (10%)
Query: 37 SGGLSIGQAGEFDY----SGSQAIKALKEANKKTI---LVNPNIATNQTSHSLADEIYYL 89
SGGL + +G G A++ ++ A++ I V I + LADE +
Sbjct: 64 SGGLGVTCSGGDKILVANRGEIAVRVIRTAHEMGIPCVAVYSTIDKDALHVKLADEAVCI 123
Query: 90 PVTPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVL-----AKYNIKVLGTPIKT 144
P +Y++ A + G T L+ G L + I +G +
Sbjct: 124 GEAPSNQSYLVIPNVLSAAISR--GCTMLHPGYGFLSENALFVEMCRDHGINFIGPNPDS 181
Query: 145 LETSEDRDLFAQALKEIDIPTAESI--ACETVDAALEAADIVGFPVIVRSAYALGGLGSG 202
+ D+ + +K +PT ++ + A+ A+ +GFPV++++ GG G
Sbjct: 182 IRVMGDKATARETMKNAGVPTVPGSDGLLQSTEEAVRVANEIGFPVMIKATAGGGGRGMR 241
Query: 203 FANNAQEMKQLASQSLSLAPQIL------VEKSLKGWKEVEYEVVRDRVGNCITV----C 252
A E +L Q+ S A +EK ++ + +E++V+ D+ GN + C
Sbjct: 242 LAKEPGEFVKLLQQAKSEAAAAFGNDGCYLEKFVQNPRHIEFQVLADKFGNVVHFGERDC 301
Query: 253 NMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYAL 307
+++ + APS L+ E + AA+ +G IG V++ L
Sbjct: 302 SIQR------RNQKLLEEAPSPALTAELRKAMGDAAVAAAASIGYIGVGTVEFLL 350
>SPAC56E4.04c [I] KOG0368 Acetyl-CoA carboxylase
Length = 2280
Score = 52.4 bits (124), Expect = 4e-06
Identities = 39/202 (19%), Positives = 87/202 (42%), Gaps = 12/202 (5%)
Query: 161 IDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSL 220
+D + + + + A+ +G+PV+++++ GG G + ++ Q Q L
Sbjct: 232 VDDDVYQKACIRSAEEGIAVAEKIGYPVMIKASEGGGGKGIRQVTSTEKFAQAFQQVLDE 291
Query: 221 AP--QILVEKSLKGWKEVEYEVVRDRVGNCITV----CNMENFDPLGIHTGDSIVFAPSQ 274
P + V K + +E +++ D+ GN I++ C+++ I + AP+
Sbjct: 292 LPGSPVFVMKLAGQARHLEVQILADQYGNNISLFGRDCSVQRRHQKIIEEAP-VTIAPAA 350
Query: 275 TLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXXXXXXXT 334
T FH + AA+++ +G ++Y P++ + +E+N +
Sbjct: 351 T-----FHEMERAAVRLGELVGYASAGTIEYLYEPENDRFYFLELNPRLQVEHPTTEMVS 405
Query: 335 GYPLAYTAAKIALGYTLPELPN 356
G L ++A+G L +P+
Sbjct: 406 GVNLPAAQLQVAMGLPLSRIPH 427
>Hs4557833 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 703
Score = 52.4 bits (124), Expect = 4e-06
Identities = 63/314 (20%), Positives = 132/314 (41%), Gaps = 24/314 (7%)
Query: 54 QAIKALKEANKKTILVNPNIATNQTSHSLADEIYYLPVTPEYITYIIERERPDAILLTFG 113
+ I+ K+ KT+ ++ ++ + +ADE + P +Y+ +AI T
Sbjct: 52 RVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRA 111
Query: 114 GQTGLNCGVALDK---AGVLAKYNIKVLGTPIKTLETSEDR---DLFAQALKEIDIPTAE 167
G + A LA ++ +G ++ D+ L A+ + IP +
Sbjct: 112 QAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFD 171
Query: 168 SIACETVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMK---QLASQSLSLA--- 221
+ + +A A +I G+PV+++++ GG G A + +E + +L+SQ + +
Sbjct: 172 GVVKDAEEAVRIAREI-GYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGD 230
Query: 222 PQILVEKSLKGWKEVEYEVVRDRVGNCITV----CNMENFDPLGIHTGDSIVFAPSQTLS 277
++L+EK + + +E +V+ D+ GN + + C+++ + + APS L
Sbjct: 231 DRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEE------APSIFLD 284
Query: 278 DEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVNXXXXXXXXXXXXXTGYP 337
E + A+ + R + V++ L ++ +E+N TG
Sbjct: 285 AETRRAMGEQAVALARAVKYSSAGTVEF-LVDSKKNFYFLEMNTRLQVEHPVTECITGLD 343
Query: 338 LAYTAAKIALGYTL 351
L ++A GY L
Sbjct: 344 LVQEMIRVAKGYPL 357
>At1g36160 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2247
Score = 52.4 bits (124), Expect = 4e-06
Identities = 37/154 (24%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 173 TVDAALEAADIVGFPVIVRSAYALGGLGSGFANNAQEMKQLASQSLSLAP--QILVEKSL 230
T + A+ + +VG+P ++++++ GG G +N E++ L Q P I + K
Sbjct: 207 TTEEAIASCQVVGYPAMIKASWGGGGKGIRKVHNDDEVRALFKQVQGEVPGSPIFIMKVA 266
Query: 231 KGWKEVEYEVVRDRVGNCITV----CNMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRS 286
+ +E +++ D+ GN + C+++ I G I AP +T+ L
Sbjct: 267 SQSRHLEVQLLCDKHGNVSALHSRDCSVQRRHQKIIEEGP-ITVAPPETVKK-----LEQ 320
Query: 287 AAIKIIRHLGVIGECNVQYALSPDSLDYRVIEVN 320
AA ++ + + +G V+Y S D+ +Y +E+N
Sbjct: 321 AARRLAKSVNYVGAATVEYLYSMDTGEYYFLELN 354
>Hs4501855 [I] KOG0368 Acetyl-CoA carboxylase
Length = 2483
Score = 51.6 bits (122), Expect = 7e-06
Identities = 46/185 (24%), Positives = 88/185 (46%), Gaps = 18/185 (9%)
Query: 144 TLETSEDRDLFAQALKEIDIP--TAESIACETVDAALEAADIVGFPVIVRSAYALGGLGS 201
T+E +ED DL Q K I +P + + VD LEAA+ +GFP++++++ GG G
Sbjct: 408 TVEWTED-DL--QQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGI 464
Query: 202 GFANNAQEMKQLASQSLSLAP--QILVEKSLKGWKEVEYEVVRDRVGNCITV----CNME 255
+A++ L Q S P I + K + + +E +++ D+ GN +++ C+++
Sbjct: 465 RETESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQ 524
Query: 256 NFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSLDYR 315
+ AP+ F + AI++ + +G + V+Y S D +
Sbjct: 525 R------RHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDG-SFH 577
Query: 316 VIEVN 320
+E+N
Sbjct: 578 FLELN 582
>CE09857 [IE] KOG0238 3-Methylcrotonyl-CoA carboxylase biotin-containing
subunit/Propionyl-CoA carboxylase alpha chain/Acetyl-CoA
carboxylase biotin carboxylase subunit
Length = 688
Score = 51.6 bits (122), Expect = 7e-06
Identities = 64/308 (20%), Positives = 132/308 (42%), Gaps = 27/308 (8%)
Query: 25 LVEGVESVLVIGSGGLSIGQAGEFDYSGSQAIKALKEANKKTILVNPNIATNQTSHSLAD 84
L+ ++ VLV G ++I G + + +A++ ++ V LA
Sbjct: 15 LIRPIQRVLVANRGEIAIRVQNTARKMGIETVAVFSDADRNSLFVKKADKAYHIGPPLAA 74
Query: 85 EIYYLPVTPEYITYIIERERPDAILLTFGGQTGLNCGVALDKAGVLAKYNIKVLGTPIKT 144
E Y + + I R AI +G + N G A +K A+ + +G P +
Sbjct: 75 ESY---LNMDKIINSALRSGAQAIHPGYGFLSE-NAGFA-EKC---AQAGLVFIGPPAQA 126
Query: 145 LETSEDRDLFAQALKEIDIPTAESIACETV-DAALEAADI-VGFPVIVRSAYALGGLGSG 202
+ +++ Q +++ +P + E DA L+ +G+PV++++ Y GG G
Sbjct: 127 IRDMGAKNVSKQIMEDAKVPVVKGFHGEDQSDANLKKKSAEIGYPVMLKAVYGGGGKGMR 186
Query: 203 FANNAQEMKQLASQSLSLA------PQILVEKSLKGWKEVEYEVVRDRVGNCITV----C 252
A N E ++ + + + A ++LVEK ++ + VE +V D GN + + C
Sbjct: 187 IAWNEAEFEEKLASARNEAKKSFGNDEMLVEKFVEKPRHVEVQVFGDHHGNYVHLWERDC 246
Query: 253 NMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSL 312
+++ I AP+ + + L +A++ +G +G V++ + P
Sbjct: 247 SVQR------RHQKIIEEAPAPNMEHDTRVKLGESAVRAAAAVGYVGAGTVEFIMDPRG- 299
Query: 313 DYRVIEVN 320
++ +E+N
Sbjct: 300 EFYFMEMN 307
Score = 51.2 bits (121), Expect = 9e-06
Identities = 66/300 (22%), Positives = 119/300 (39%), Gaps = 19/300 (6%)
Query: 601 AVNTTKALRKEGKKTIMINYNPETVSTDFDEVDRLYF--EELSFERVMDIYELENSE--- 655
A+ RK G +T+ + + + S + D+ Y L+ E +++ ++ NS
Sbjct: 31 AIRVQNTARKMGIETVAVFSDADRNSLFVKKADKAYHIGPPLAAESYLNMDKIINSALRS 90
Query: 656 -GCVISVG-GQLPQN--IALKLLHNGAHILGTSPEDIDKAENRHKFSTILDS--IGVNQP 709
I G G L +N A K G +G + I ++ I++ + V +
Sbjct: 91 GAQAIHPGYGFLSENAGFAEKCAQAGLVFIGPPAQAIRDMGAKNVSKQIMEDAKVPVVKG 150
Query: 710 EWSELSSVEEAKVFANQVGYPVLIRPSYVLSGAAMSVVTGEHELEVKLTTASDVSP---- 765
E S K + ++GYPV+++ Y G M + E E E KL +A + +
Sbjct: 151 FHGEDQSDANLKKKSAEIGYPVMLKAVYGGGGKGMRIAWNEAEFEEKLASARNEAKKSFG 210
Query: 766 DHPVVMSKFIEGAQEIDVDAVAHNGMVLVHAISEHVENAGIHSGDATLVLPPQNLSQNIK 825
+ +++ KF+E + ++V + VH H P N+ + +
Sbjct: 211 NDEMLVEKFVEKPRHVEVQVFGDHHGNYVHLWERDCSVQRRHQ-KIIEEAPAPNMEHDTR 269
Query: 826 DRLKEIADKVAKAWNITGPFNMQIIKDDRDEGVSLKVIECNIRASRSFPFVSKVLGVNFI 885
+L E A + A A G ++ I D R E +E N R P + G++FI
Sbjct: 270 VKLGESAVRAAAAVGYVGAGTVEFIMDPRGE---FYFMEMNTRLQVEHPVSEAITGIDFI 326
>YNR016c [I] KOG0368 Acetyl-CoA carboxylase
Length = 2233
Score = 51.2 bits (121), Expect = 9e-06
Identities = 46/216 (21%), Positives = 90/216 (41%), Gaps = 17/216 (7%)
Query: 139 GTPIKTLETSEDRDLFAQALKEIDIPTAESIACETVDAALEAADIVGFPVIVRSAYALGG 198
GT + T+ E L + +D + C + + L+ A +GFPV+++++ GG
Sbjct: 205 GTGVDTVHVDEKTGLVS-----VDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGG 259
Query: 199 LGSGFANNAQEMKQLASQSLSLAP--QILVEKSLKGWKEVEYEVVRDRVGNCITV----C 252
G ++ L Q+ + P I + K + +E +++ D+ G I++ C
Sbjct: 260 KGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDC 319
Query: 253 NMENFDPLGIHTGDSIVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALSPDSL 312
+++ I AP E FH + AA+++ + +G + V+Y S D
Sbjct: 320 SVQRRHQKIIEE------APVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDG 373
Query: 313 DYRVIEVNXXXXXXXXXXXXXTGYPLAYTAAKIALG 348
+ +E+N +G L +IA+G
Sbjct: 374 KFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMG 409
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,717,280
Number of Sequences: 60738
Number of extensions: 2632320
Number of successful extensions: 6872
Number of sequences better than 1.0e-05: 30
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 6665
Number of HSP's gapped (non-prelim): 62
length of query: 1117
length of database: 30,389,216
effective HSP length: 117
effective length of query: 1000
effective length of database: 23,282,870
effective search space: 23282870000
effective search space used: 23282870000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)