ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI0949 good E KOG0633 Amino acid transport and metabolism Histidinol phosphate aminotransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI0949 327598 328758 387
(387 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL116w [E] KOG0633 Histidinol phosphate aminotransferase 451 e-126
SPBC11B10.02c [E] KOG0633 Histidinol phosphate aminotransferase 314 2e-85
At5g10330 [E] KOG0633 Histidinol phosphate aminotransferase 138 1e-32
At1g71920 [E] KOG0633 Histidinol phosphate aminotransferase 138 1e-32
At2g22250 [E] KOG0257 Kynurenine aminotransferase glutamine tran... 61 2e-09
At3g49700 [T] KOG0256 1-aminocyclopropane-1-carboxylate synthase... 55 2e-07
At5g65800 [T] KOG0256 1-aminocyclopropane-1-carboxylate synthase... 53 7e-07
At4g08040 [T] KOG0256 1-aminocyclopropane-1-carboxylate synthase... 52 1e-06
At5g53970 [E] KOG0259 Tyrosine aminotransferase 51 3e-06
>YIL116w [E] KOG0633 Histidinol phosphate aminotransferase
Length = 385
Score = 451 bits (1159), Expect = e-126
Identities = 231/385 (60%), Positives = 280/385 (72%), Gaps = 9/385 (2%)
Query: 1 MTFDIAKVVRPKILNLEPYRCARDDFQEGILLDANENPYGPTIQEYNVDSLLHRYPDPHQ 60
M FD+ ++VRPKI NLEPYRCARDDF EGILLDANEN +GPT E + +L HRYPDPHQ
Sbjct: 1 MVFDLKRIVRPKIYNLEPYRCARDDFTEGILLDANENAHGPTPVELSKTNL-HRYPDPHQ 59
Query: 61 LEFKKLLSDYRNKTSIF-KDQNLKPLDADNLCLGVGSDESIDALIRACCVPAKEKILIAP 119
LEFK ++ YRNKTS + D +KPL ADNLCLGVGSDESIDA+IRACCVP KEKIL+ P
Sbjct: 60 LEFKTAMTKYRNKTSSYANDPEVKPLTADNLCLGVGSDESIDAIIRACCVPGKEKILVLP 119
Query: 120 ATYGMYTICSQVNDVEYVTVPLLLSEEDKFQIDEEKILETLQNDPSIKLVFITSPGNPTG 179
TY MY++C+ +ND+E V PL +S + FQ+D E +L L+ND IKL+F+TSPGNPTG
Sbjct: 120 PTYSMYSVCANINDIEVVQCPLTVS-DGSFQMDTEAVLTILKNDSLIKLMFVTSPGNPTG 178
Query: 180 TFIDVNRIEKILSQWQTGLVVVDEAYIDFVEGSDKGSLAPLATKYENIAVLQTLSKSFGL 239
I + IEK+L W GLVVVDEAY+DF GS APL TKY N+ LQTLSKSFGL
Sbjct: 179 AKIKTSLIEKVLQNWDNGLVVVDEAYVDFC----GGSTAPLVTKYPNLVTLQTLSKSFGL 234
Query: 240 AGIRLGVTYTSKAMSRVLNSMKAPYNISCSTAEVALKAVQPKNLKLMEENAATXXXXXXX 299
AGIRLG+TY + ++R+LN+MKAPYNIS +E ALKAVQ NLK ME +
Sbjct: 235 AGIRLGMTYATAELARILNAMKAPYNISSLASEYALKAVQDSNLKKMEATSKIINEEKMR 294
Query: 300 XXXXXTSSPYVSQ--LGGLDANFILLNINNGDNALTKKLYERLAVESAVITRYRGNEPGC 357
T+ YV +GGLDANF+L+ IN GDN L KKLY +LA +S V+ R+RGNE GC
Sbjct: 295 LLKELTALDYVDDQYVGGLDANFLLIRINGGDNVLAKKLYYQLATQSGVVVRFRGNELGC 354
Query: 358 AGGLRITIGTKQENDVLIKEFRKHL 382
+G LRIT+GT +EN LIK F++ L
Sbjct: 355 SGCLRITVGTHEENTHLIKYFKETL 379
>SPBC11B10.02c [E] KOG0633 Histidinol phosphate aminotransferase
Length = 384
Score = 314 bits (804), Expect = 2e-85
Identities = 180/386 (46%), Positives = 237/386 (60%), Gaps = 22/386 (5%)
Query: 3 FDIAKVVRPKILNLEPYRCARDDFQEGILLDANENPYGPTIQEYNVDSLLHRYPDPHQLE 62
FD+ +R IL L+PYRCARDDF EG+LLDANE YG I V+ +RYPDP Q+E
Sbjct: 2 FDLNTCLRKNILELQPYRCARDDFSEGVLLDANECAYGSVISVDGVE--FNRYPDPRQIE 59
Query: 63 FKKLLSDYRNKTSIFKDQNLKPLDADNLCLGVGSDESIDALIRACCVPAKEKILIAPATY 122
K+ L D RNK KPL DN+C+GVGSDE ID+LIR C+P K+KIL+ P +Y
Sbjct: 60 VKQRLCDLRNKELSIT----KPLTPDNICMGVGSDEIIDSLIRISCIPGKDKILMCPPSY 115
Query: 123 GMYTICSQVNDVEYVTVPLLLSEEDKFQIDEEKILETLQNDPSIKLVFITSPGNPTGTFI 182
GMYT+ +++NDVE V V L E F ++ + I ETL D +IK+ F SPGNPT +
Sbjct: 116 GMYTVSAKINDVEVVKVLL----EPDFNLNVDAICETLSKDSAIKVFFACSPGNPTAKAL 171
Query: 183 DVNRIEKILSQ--WQTGLVVVDEAYIDFVEGSDKGSLAPLATKYENIAVLQTLSKSFGLA 240
+ I+KIL W G+VVVDEAYIDF D +L L +Y N+AV QTLSKSFGLA
Sbjct: 172 KLEDIKKILEHPTW-NGIVVVDEAYIDF-SAPDMSALT-LVNEYPNLAVCQTLSKSFGLA 228
Query: 241 GIRLGVTYTSKAMSRVLNSMKAPYNISCSTAEVALKAVQPKNL-KLMEENAATXXXXXXX 299
GIR+G TSK ++ ++NS+KAPYNIS T+ +AL A+ P+++ K+ A
Sbjct: 229 GIRIGFCLTSKPIATIMNSLKAPYNISEPTSRLALDALSPQSIDKMHTYRDAIIQQRVRL 288
Query: 300 XXXXXTSSPYVSQLGGLDANFILLNI------NNGDNALTKKLYERLAVESAVITRYRGN 353
T +GG DANFIL+ + N K LY ++A V+ R+RG
Sbjct: 289 CKELTTIKGMGKIIGGYDANFILIQVLDRPEGGKPSNDAAKYLYLQMATMHKVVVRFRGT 348
Query: 354 EPGCAGGLRITIGTKQENDVLIKEFR 379
EP C G LRIT+GT++EN +L+K +
Sbjct: 349 EPLCEGALRITVGTEEENTILLKTIK 374
>At5g10330 [E] KOG0633 Histidinol phosphate aminotransferase
Length = 415
Score = 138 bits (348), Expect = 1e-32
Identities = 110/349 (31%), Positives = 170/349 (48%), Gaps = 33/349 (9%)
Query: 30 ILLDANENPYGPTIQEYNVDSLL--HRYPDPHQLEFKKLLSDYRNKTSIFKDQNLKPLDA 87
+ LDANENPYGP E + ++ + YPDP + L+ L++
Sbjct: 92 VKLDANENPYGPP-PEATLGNMKFPYVYPDPQSRRLRDALAQDSG------------LES 138
Query: 88 DNLCLGVGSDESIDALIRACCVPAKEKILIAPATYGMYTICSQVNDVEYVTVPLLLSEED 147
+ + +G G+DE ID ++R C + EKI+ P T+ MY + VN + VP
Sbjct: 139 EYILVGCGADELIDLIMR-CVLDPGEKIIDCPPTFSMYVFDAAVNGAGVIKVP----RNP 193
Query: 148 KFQIDEEKILETLQNDPSIKLVFITSPGNPTGTFIDVNRIEKILSQWQTGLVVVDEAYID 207
F ++ ++I E ++ + K +F+TSP NP G+ I + + KIL LVV+DEAYI+
Sbjct: 194 DFSLNVDRIAEVVELEKP-KCIFLTSPNNPDGSIISEDDLLKILEM--PILVVLDEAYIE 250
Query: 208 FVEGSDKGSLAPLATKYENIAVLQTLSKSFGLAGIRLGVTYTSKAMSRVLNSMKAPYNIS 267
F S S KYEN+ VL+T SK GLAG+R+G ++ L K PYN+S
Sbjct: 251 F---SGVESRMKWVKKYENLIVLRTFSKRAGLAGLRVGYGAFPLSIIEYLWRAKQPYNVS 307
Query: 268 CSTAEVALKAVQPKNLKLMEENAATXXXXXXXXXXXXTSSPYVSQLGGLDANFILLNINN 327
+ AL A+ N K +E+ P+++ +NFIL + +
Sbjct: 308 VAGEVAALAAL--SNGKYLEDVRDALVRERERLFGLLKEVPFLNPYPSY-SNFILCEVTS 364
Query: 328 GDNALTKKLYERLAVESAVITRYRGNEPGCAGGLRITIGTKQENDVLIK 376
G +A KKL E LA ++ Y E G +R++ G + DVL++
Sbjct: 365 GMDA--KKLKEDLAKMGVMVRHYNSQE--LKGYVRVSAGKPEHTDVLME 409
>At1g71920 [E] KOG0633 Histidinol phosphate aminotransferase
Length = 415
Score = 138 bits (348), Expect = 1e-32
Identities = 110/349 (31%), Positives = 170/349 (48%), Gaps = 33/349 (9%)
Query: 30 ILLDANENPYGPTIQEYNVDSLL--HRYPDPHQLEFKKLLSDYRNKTSIFKDQNLKPLDA 87
+ LDANENPYGP E + ++ + YPDP + L+ L++
Sbjct: 92 VKLDANENPYGPP-PEATLGNMKFPYVYPDPQSRRLRDALAQDSG------------LES 138
Query: 88 DNLCLGVGSDESIDALIRACCVPAKEKILIAPATYGMYTICSQVNDVEYVTVPLLLSEED 147
+ + +G G+DE ID ++R C + EKI+ P T+ MY + VN + VP
Sbjct: 139 EYILVGCGADELIDLIMR-CVLDPGEKIIDCPPTFSMYVFDAAVNGAGVIKVP----RNP 193
Query: 148 KFQIDEEKILETLQNDPSIKLVFITSPGNPTGTFIDVNRIEKILSQWQTGLVVVDEAYID 207
F ++ ++I E ++ + K +F+TSP NP G+ I + + KIL LVV+DEAYI+
Sbjct: 194 DFSLNVDRIAEVVELEKP-KCIFLTSPNNPDGSIISEDDLLKILEM--PILVVLDEAYIE 250
Query: 208 FVEGSDKGSLAPLATKYENIAVLQTLSKSFGLAGIRLGVTYTSKAMSRVLNSMKAPYNIS 267
F S S KYEN+ VL+T SK GLAG+R+G ++ L K PYN+S
Sbjct: 251 F---SGVESRMKWVKKYENLIVLRTFSKRAGLAGLRVGYGAFPLSIIEYLWRAKQPYNVS 307
Query: 268 CSTAEVALKAVQPKNLKLMEENAATXXXXXXXXXXXXTSSPYVSQLGGLDANFILLNINN 327
+ AL A+ N K +E+ P+++ +NFIL + +
Sbjct: 308 VAGEVAALAAL--SNGKYLEDVRDALVRERERLFGLLKEVPFLNPYPSY-SNFILCEVTS 364
Query: 328 GDNALTKKLYERLAVESAVITRYRGNEPGCAGGLRITIGTKQENDVLIK 376
G +A KKL E LA ++ Y E G +R++ G + DVL++
Sbjct: 365 GMDA--KKLKEDLAKMGVMVRHYNSQE--LKGYVRVSAGKPEHTDVLME 409
>At2g22250 [E] KOG0257 Kynurenine aminotransferase glutamine transaminase K
Length = 406
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/204 (27%), Positives = 96/204 (46%), Gaps = 11/204 (5%)
Query: 78 KDQNLKPLDADNLCLGVGSDESIDALIRACCVPAKEKILIAPATYGMYTICSQVNDVEYV 137
K++N D + + G+ +S+ + A C P E I+ AP + YT +++ D V
Sbjct: 81 KEENGLSYAPDQILVSNGAKQSLLQAVLAVCSPGDEVIIPAPY-WVSYTEQARLADATPV 139
Query: 138 TVPLLLSEEDKFQIDEEKILETLQNDPSIKLVFITSPGNPTGTFIDVNRIE---KILSQW 194
+P +S + F +D K LE+ + S +L+ + SP NPTG+ + +E +I+++
Sbjct: 140 VIPTKIS--NNFLLDP-KDLESKLTEKS-RLLILCSPSNPTGSVYPKSLLEEIARIIAKH 195
Query: 195 QTGLVVVDEAYIDFVEG-SDKGSLAPLATKYENIAVLQTLSKSFGLAGIRLGVTYTSKAM 253
LV+ DE Y + + S A L YE + SK+F + G RLG Y +
Sbjct: 196 PRLLVLSDEIYEHIIYAPATHTSFASLPDMYERTLTVNGFSKAFAMTGWRLG--YLAGPK 253
Query: 254 SRVLNSMKAPYNISCSTAEVALKA 277
V K +S + +A KA
Sbjct: 254 HIVAACSKLQGQVSSGASSIAQKA 277
>At3g49700 [T] KOG0256 1-aminocyclopropane-1-carboxylate synthase and related
proteins
Length = 470
Score = 55.1 bits (131), Expect = 2e-07
Identities = 57/241 (23%), Positives = 95/241 (38%), Gaps = 24/241 (9%)
Query: 55 YPDPHQL-EFKKLLSDYRNKTSIFKDQNLKPLDADNLCLGVGSDESIDALIRACCVPAKE 113
+ D H L EFKK L+++ + N D + L GS + + L+ P
Sbjct: 82 FQDYHGLPEFKKALAEFMEEIR----GNRVTFDPSKIVLAAGSTSANETLMFCLAEPGDA 137
Query: 114 KILIAPATYGMYTICSQVNDVEYVTVPLLLSEEDKFQIDEEKILETLQN----DPSIKLV 169
+L P G E V P+ S + FQI E + + Q D +K V
Sbjct: 138 FLLPTPYYPGFDRDLKWRTGAEIV--PIHCSSSNGFQITESALQQAYQQAQKLDLKVKGV 195
Query: 170 FITSPGNPTGT------------FIDVNRIEKILSQWQTGLVVVDEAYIDFVEGSDKGSL 217
+T+P NP GT FI I I + +G V E ++ ++ +L
Sbjct: 196 LVTNPSNPLGTMLTRRELNLLVDFITSKNIHLISDEIYSGTVFGFEQFVSVMDVLKDKNL 255
Query: 218 APLATKYENIAVLQTLSKSFGLAGIRLGVTYTSKAMSRVLNSMKAPYNISCSTAEVALKA 277
+ + ++ +LSK GL G R+G Y++ M + + + + S + L A
Sbjct: 256 ENSEVS-KRVHIVYSLSKDLGLPGFRVGAIYSNDEMVVSAATKMSSFGLVSSQTQYLLSA 314
Query: 278 V 278
+
Sbjct: 315 L 315
>At5g65800 [T] KOG0256 1-aminocyclopropane-1-carboxylate synthase and related
proteins
Length = 470
Score = 53.1 bits (126), Expect = 7e-07
Identities = 56/241 (23%), Positives = 94/241 (38%), Gaps = 24/241 (9%)
Query: 55 YPDPHQL-EFKKLLSDYRNKTSIFKDQNLKPLDADNLCLGVGSDESIDALIRACCVPAKE 113
+ D H + EFKK ++++ + N D + L GS + + L+ P
Sbjct: 82 FQDYHGMPEFKKAMAEFMEEIR----GNRVTFDPKKIVLAAGSTSANETLMFCLAEPGDA 137
Query: 114 KILIAPATYGMYTICSQVNDVEYVTVPLLLSEEDKFQIDEEKILETLQN----DPSIKLV 169
+L P G E V P+ S + FQI E + + Q D +K V
Sbjct: 138 FLLPTPYYPGFDRDLKWRTGAEIV--PIHCSSSNGFQITESALQQAYQQAQKLDLKVKGV 195
Query: 170 FITSPGNPTGT------------FIDVNRIEKILSQWQTGLVVVDEAYIDFVEGSDKGSL 217
+T+P NP GT FI I I + +G + E +I ++ L
Sbjct: 196 LVTNPSNPLGTALTRRELNLLVDFITSKNIHLISDEIYSGTMFGFEQFISVMDVLKDKKL 255
Query: 218 APLATKYENIAVLQTLSKSFGLAGIRLGVTYTSKAMSRVLNSMKAPYNISCSTAEVALKA 277
+ + V+ +LSK GL G R+G Y++ M + + + + S + L A
Sbjct: 256 EDTEVS-KRVHVVYSLSKDLGLPGFRVGAIYSNDEMIVSAATKMSSFGLVSSQTQYLLSA 314
Query: 278 V 278
+
Sbjct: 315 L 315
>At4g08040 [T] KOG0256 1-aminocyclopropane-1-carboxylate synthase and related
proteins
Length = 460
Score = 52.4 bits (124), Expect = 1e-06
Identities = 54/207 (26%), Positives = 89/207 (42%), Gaps = 15/207 (7%)
Query: 55 YPDPHQLE-FKKLLSDYRNKTSIFKDQNLKPLDADNLCLGVGSDESIDALIRACCVPAKE 113
+ D H L FK ++ + K +N D + + L GS + + L+ P
Sbjct: 80 FQDYHGLPAFKDAMAKFMGKIR----ENKVKFDTNKMVLTAGSTSANETLMFCLANPGDA 135
Query: 114 KILIAPATYGMYTICSQVNDVEYVTVPLLLSEEDKFQID--EEKILETLQNDPSIKLVFI 171
++ AP G VE V + + S K D E+ L+++ ++K V I
Sbjct: 136 FLIPAPYYPGFDRDLKWRTGVEIVPIHCVSSNGYKITEDALEDAYERALKHNLNVKGVLI 195
Query: 172 TSPGNPTGTFIDVNRIEKILSQWQTGLV--VVDEAYIDFVEGSDKGSLAPLATKYEN--- 226
T+P NP GT ++ +L+ T + V DE Y V S + + K +N
Sbjct: 196 TNPSNPLGTSTTREELDLLLTFTSTKKIHMVSDEIYSGTVFDSPEFTSVLEVAKDKNMGL 255
Query: 227 ---IAVLQTLSKSFGLAGIRLGVTYTS 250
I V+ +LSK GL G R+G+ Y++
Sbjct: 256 DGKIHVVYSLSKDLGLPGFRVGLIYSN 282
>At5g53970 [E] KOG0259 Tyrosine aminotransferase
Length = 414
Score = 50.8 bits (120), Expect = 3e-06
Identities = 59/211 (27%), Positives = 100/211 (46%), Gaps = 32/211 (15%)
Query: 49 DSLL----HRY-PDPHQLEFKKLLSDYRNKTSIFKDQNLKPLDADNLCLGVGSDESIDAL 103
DSLL H Y P + ++ +++Y ++ +K L D++ + G ++ID
Sbjct: 61 DSLLSNKFHGYSPTVGLPQARRAIAEYLSRDLPYK------LSQDDVFITSGCTQAIDVA 114
Query: 104 IRACCVPAKEKILIAPATYGMYTICSQVNDVEYVTVPLLLSEEDKFQIDEEKILETLQND 163
+ P + IL+ + +Y +C++ +E V LL E+ ++ID + + E L ++
Sbjct: 115 LSMLARP-RANILLPRPGFPIYELCAKFRHLEVRYVDLL--PENGWEIDLDAV-EALADE 170
Query: 164 PSIKLVFITSPGNPTGTFIDVNRIEKIL-SQWQTG-LVVVDEAYIDFVEGSDK------- 214
++ LV I +PGNP G + KI S + G LV+ DE Y GS
Sbjct: 171 NTVALVVI-NPGNPCGNVYSYQHLMKIAESAKKLGFLVIADEVYGHLAFGSKPFVPMGVF 229
Query: 215 GSLAPLATKYENIAVLQTLSKSFGLAGIRLG 245
GS+ P+ T L +LSK + + G RLG
Sbjct: 230 GSIVPVLT-------LGSLSKRWIVPGWRLG 253
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,287,039
Number of Sequences: 60738
Number of extensions: 942774
Number of successful extensions: 2167
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2139
Number of HSP's gapped (non-prelim): 9
length of query: 387
length of database: 30,389,216
effective HSP length: 108
effective length of query: 279
effective length of database: 23,829,512
effective search space: 6648433848
effective search space used: 6648433848
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)