ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI1112 good E KOG0784 Amino acid transport and metabolism Isocitrate dehydrogenase, gamma subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI1112 389159 390241 361
(361 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL037c [E] KOG0784 Isocitrate dehydrogenase gamma subunit 567 e-161
SPAC11G7.03 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 456 e-128
Hs4758582 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 337 1e-92
7300799 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 336 4e-92
Hs5901982 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 332 7e-91
CE08620 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 331 9e-91
At4g35260 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 328 1e-89
At4g35650 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 323 3e-88
CE16887 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 322 4e-88
CE00970 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 321 9e-88
7301367 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 321 9e-88
At2g17130 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 318 8e-87
7293593 [E] KOG0785 Isocitrate dehydrogenase alpha subunit 314 1e-85
At5g03290 [E] KOG0785 Isocitrate dehydrogenase alpha subunit 304 1e-82
At3g09805 [E] KOG0785 Isocitrate dehydrogenase alpha subunit 295 9e-80
CE10354 [E] KOG0785 Isocitrate dehydrogenase alpha subunit 293 3e-79
SPBC902.05c [E] KOG0785 Isocitrate dehydrogenase alpha subunit 290 2e-78
Hs5031777 [E] KOG0785 Isocitrate dehydrogenase alpha subunit 287 2e-77
YOR136w [E] KOG0785 Isocitrate dehydrogenase alpha subunit 286 2e-77
7291785 [E] KOG0785 Isocitrate dehydrogenase alpha subunit 207 1e-53
YIL094c [E] KOG0785 Isocitrate dehydrogenase alpha subunit 182 5e-46
SPAC31G5.04 [E] KOG0785 Isocitrate dehydrogenase alpha subunit 174 1e-43
At1g32480 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 159 6e-39
At1g31180 [E] KOG0786 3-isopropylmalate dehydrogenase 140 2e-33
At5g14200 [E] KOG0786 3-isopropylmalate dehydrogenase 139 5e-33
At1g80560 [E] KOG0786 3-isopropylmalate dehydrogenase 134 3e-31
YCL018w [E] KOG0786 3-isopropylmalate dehydrogenase 117 3e-26
7302952 [E] KOG0784 Isocitrate dehydrogenase gamma subunit 114 2e-25
SPBC1A4.02c [E] KOG0786 3-isopropylmalate dehydrogenase 100 4e-21
>YNL037c [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 360
Score = 567 bits (1461), Expect = e-161
Identities = 284/362 (78%), Positives = 323/362 (88%), Gaps = 3/362 (0%)
Query: 1 MLRQGIAAQKKSFATLA-AEQLLPKKYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPI 59
ML + IA K++ AT A AE+ LPKKYGGR+TVTLIPGDGVGKE+TDSV IFE ENIPI
Sbjct: 1 MLNRTIA--KRTLATAAQAERTLPKKYGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPI 58
Query: 60 DWETIDISGLENTENVQRAVESLKRNKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANV 119
DWETI+I ++ E V AVESLKRNK+GLKG+WHTPADQTGHGSLNVALRKQLDI+ANV
Sbjct: 59 DWETINIKQTDHKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANV 118
Query: 120 ALFKSIPGVKTRLNNIDMVIIRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAF 179
ALFKS+ GVKTR+ +ID+++IRENTEGE+SGLEHESVPGVVESLK+MTR K+ERIARFAF
Sbjct: 119 ALFKSLKGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAF 178
Query: 180 DFALKNNRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKP 239
DFA K NRKSV AVHKANIMKLGDGLFRN + EIG EYP++DV +IIVDNASMQAVAKP
Sbjct: 179 DFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKP 238
Query: 240 HQFDVLVTPNLYGSILGNIGSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVAN 299
HQFDVLVTP++YG+ILGNIG+ALIGGPGLV GANFGR+YAVFEPGSRHVGLDIKGQNVAN
Sbjct: 239 HQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVAN 298
Query: 300 PTAMILSSTLMLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKLA 359
PTAMILSSTLML HLGLN YA RISKA ++ I+EGK TTRDIGGS+ST++FTN +I KL+
Sbjct: 299 PTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLS 358
Query: 360 KL 361
+
Sbjct: 359 TM 360
>SPAC11G7.03 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 356
Score = 456 bits (1173), Expect = e-128
Identities = 224/344 (65%), Positives = 280/344 (81%), Gaps = 6/344 (1%)
Query: 23 PKKYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTEN-----VQR 77
P KYGG+YTVTLIPGDG+G+E +++V +IF+ N+PI++E ID++G+E +
Sbjct: 14 PLKYGGKYTVTLIPGDGIGRETSNAVTEIFKTANVPIEFEEIDVTGMEKNNKSSGDALHE 73
Query: 78 AVESLKRNKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDM 137
A++SLKRNKVGLKGI TP ++ GH S NVALRK+LDI+A++ L K+IPG KTR +N+D
Sbjct: 74 AIQSLKRNKVGLKGILFTPFEKGGHTSFNVALRKELDIYASLVLIKNIPGFKTRHDNVDF 133
Query: 138 VIIRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKAN 197
IIRENTEGEYSGLEH+SVPGVVESLKI+T KS+RIA+FAFDFAL+N RKSV +HKAN
Sbjct: 134 AIIRENTEGEYSGLEHQSVPGVVESLKIITEYKSKRIAQFAFDFALQNGRKSVTCIHKAN 193
Query: 198 IMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGN 257
IMKL DGLFR T ++ AN Y + K++IVDNASMQAV++P QFDVLV PNLYGSIL N
Sbjct: 194 IMKLADGLFRRTFYDV-ANGYDAITPKDLIVDNASMQAVSRPQQFDVLVMPNLYGSILSN 252
Query: 258 IGSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLN 317
IGSAL+GGPG++PGANFGR+YA+FEPG RHVGL I G+ ANPTA ILS+ LMLRHLGL
Sbjct: 253 IGSALVGGPGVIPGANFGRDYALFEPGCRHVGLSITGRGEANPTAAILSACLMLRHLGLK 312
Query: 318 AYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKLAKL 361
YAD I+ ATY VI EGK+ T+D+GGSAST +FT+A++E++ L
Sbjct: 313 DYADLINAATYSVIEEGKTLTKDLGGSASTGDFTHAILERMESL 356
>Hs4758582 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 393
Score = 337 bits (865), Expect = 1e-92
Identities = 177/356 (49%), Positives = 242/356 (67%), Gaps = 4/356 (1%)
Query: 6 IAAQKKSFATLAAEQLLPK--KYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWET 63
+ A + + +EQ +P KYGGR+TVT+IPGDG+G E+ V +F + +P+D+E
Sbjct: 29 LGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEE 88
Query: 64 IDISGLENTENVQRAVESLKRNKVGLKGIWHTPAD-QTGHGSLNVALRKQLDIFANVALF 122
+ +S + E+++ A+ +++RN+V LKG T + H S N LR LD++ANV
Sbjct: 89 VHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHC 148
Query: 123 KSIPGVKTRLNNIDMVIIRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFA 182
KS+PGV TR +ID++I+RENTEGEYS LEHESV GVVESLKI+T+AKS RIA +AF A
Sbjct: 149 KSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLA 208
Query: 183 LKNNRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQF 242
++ RK V AVHKANIMKLGDGLF E+ A YP++ +N+IVDN +MQ V++P QF
Sbjct: 209 QESGRKKVTAVHKANIMKLGDGLFLQCCREVAAR-YPQITFENMIVDNTTMQLVSRPQQF 267
Query: 243 DVLVTPNLYGSILGNIGSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTA 302
DV+V PNLYG+I+ N+ + L+GGPGLV GAN+G YAVFE +R+ G I +N+ANPTA
Sbjct: 268 DVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTA 327
Query: 303 MILSSTLMLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKL 358
+L+S +ML HL L++YA I KA + T DIGG +TSE VI +
Sbjct: 328 TLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383
>7300799 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 370
Score = 336 bits (861), Expect = 4e-92
Identities = 176/354 (49%), Positives = 242/354 (67%), Gaps = 7/354 (1%)
Query: 7 AAQKKSFATLAAEQLLPKKYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDI 66
AA +S T + + R T TLIPGDGVG E+ S+ ++F+ ++P+D+E +
Sbjct: 15 AAAARSLHTTSTLRATDNYGANRTTCTLIPGDGVGPELVYSLQEVFKAASVPVDFECYFL 74
Query: 67 SGLEN--TENVQRAVESLKRNKVGLKGIWHTPADQTGHG---SLNVALRKQLDIFANVAL 121
S + + ++ V S+++NKV +KG+ TP D + G +LN+ LR LD++ANV
Sbjct: 75 SEINPVLSAKLEDVVASIQKNKVCIKGVLATP-DYSNVGDLQTLNMKLRNDLDLYANVVH 133
Query: 122 FKSIPGVKTRLNNIDMVIIRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDF 181
+S+PGVKTR NID VIIRE TEGEYS LEHESVPG+VE LKI+T KS RIA+FAFD+
Sbjct: 134 VRSLPGVKTRHTNIDTVIIREQTEGEYSALEHESVPGIVECLKIITAKKSMRIAKFAFDY 193
Query: 182 ALKNNRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQ 241
A KN RK V AVHKANIMKLGDGLF + E+ + YP + + +IVDN +MQ V+ P+Q
Sbjct: 194 ATKNQRKKVTAVHKANIMKLGDGLFLRSCEEV-SRLYPRIQFEKMIVDNTTMQMVSNPNQ 252
Query: 242 FDVLVTPNLYGSILGNIGSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPT 301
FDV+VTPNLYG+I+ N+ S L+GG G+V GA++ E VFEPG+RH + G+NVANPT
Sbjct: 253 FDVMVTPNLYGAIVDNLASGLVGGAGVVAGASYSSESVVFEPGARHTFAEAVGKNVANPT 312
Query: 302 AMILSSTLMLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVI 355
AM+L +LRH+ L Y + I A V+++GK T+D+GG ++T +FT A+I
Sbjct: 313 AMLLCGVKLLRHINLPTYGEIIQNAINKVLNDGKVRTKDLGGQSTTQDFTRAII 366
>Hs5901982 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 385
Score = 332 bits (850), Expect = 7e-91
Identities = 169/335 (50%), Positives = 235/335 (69%), Gaps = 5/335 (1%)
Query: 28 GRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENT---ENVQRAVESLKR 84
G + VT++PGDGVG E+ +V ++F+ +P++++ +S ++N E +++ + S+K
Sbjct: 47 GSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKE 106
Query: 85 NKVGLKGIWHTPADQTGH-GSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIREN 143
NKV + G HTP + G S ++ LR++LD+FANV KS+PG TR NN+D+VIIRE
Sbjct: 107 NKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQ 166
Query: 144 TEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGD 203
TEGEYS LEHES GV+E LKI+TRAKS+RIA+FAFD+A K R V AVHKANIMKLGD
Sbjct: 167 TEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGD 226
Query: 204 GLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALI 263
GLF E+ A YP++ + +I+DN MQ V P+QFDVLV PNLYG+I+ N+ + L+
Sbjct: 227 GLFLQCCEEV-AELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLV 285
Query: 264 GGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNAYADRI 323
GG G+VPG ++ EYAVFE G+RH G+N+ANPTAM+LS++ MLRHL L ++ I
Sbjct: 286 GGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMI 345
Query: 324 SKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKL 358
+ A VI GK TRD+GG ++T++F +VI L
Sbjct: 346 ADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHL 380
>CE08620 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 379
Score = 331 bits (849), Expect = 9e-91
Identities = 178/361 (49%), Positives = 245/361 (67%), Gaps = 16/361 (4%)
Query: 7 AAQKKSFATLAAEQLLPKKYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDI 66
AA + ++ A P + + VT+IPGDGVG E+ +V I + IPI++E I +
Sbjct: 22 AASSRQYSITAPRP--PTELNQKLKVTIIPGDGVGPELIYTVQDIVKQTGIPIEFEEIFL 79
Query: 67 SGLENTEN--VQRAVESLKRNK-VGLKG------IWHTPADQTGHGSLNVALRKQLDIFA 117
S + T + ++ AVES+ RN V LKG + HT + G LN+ LR+ LD+FA
Sbjct: 80 SEVHYTRSSSIENAVESIGRNNNVALKGAIEESAVLHTEGELQG---LNMRLRRSLDLFA 136
Query: 118 NVALFKSIPGVKTRLNN-IDMVIIRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIAR 176
NV K++ G+KTR +D VI+RE TEGEYS LEHE VPGV+E LKI TR K+ERIA+
Sbjct: 137 NVVHIKTLDGIKTRHGKQLDFVIVREQTEGEYSSLEHELVPGVIECLKISTRTKAERIAK 196
Query: 177 FAFDFALKNNRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAV 236
FAFD+A K RK V AVHKANIMKLGDGLF T + A +YP++ +++I+DN MQ V
Sbjct: 197 FAFDYATKTGRKKVTAVHKANIMKLGDGLFLRTCEGV-AKQYPKIQFESMIIDNTCMQLV 255
Query: 237 AKPHQFDVLVTPNLYGSILGNIGSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQN 296
+KP QFDV+V PNLYG+I+ N+ + L+GG G+VPG + GR++ +FEPGSRH + G++
Sbjct: 256 SKPEQFDVMVMPNLYGNIIDNLAAGLVGGAGVVPGQSVGRDFVIFEPGSRHSFQEAMGRS 315
Query: 297 VANPTAMILSSTLMLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVIE 356
+ANPTAMIL + ML HL L+A+ + + +A DV+ EGK TRD+GG A+T +F +AVI+
Sbjct: 316 IANPTAMILCAANMLNHLHLDAWGNSLRQAVADVVKEGKVRTRDLGGYATTVDFADAVID 375
Query: 357 K 357
K
Sbjct: 376 K 376
>At4g35260 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 367
Score = 328 bits (840), Expect = 1e-89
Identities = 176/335 (52%), Positives = 237/335 (70%), Gaps = 6/335 (1%)
Query: 27 GGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENVQRAVESLKRNK 86
G VTLIPGDG+G VT++V ++ E + PI +E D+ G E + +ES+++NK
Sbjct: 35 GAPRAVTLIPGDGIGPLVTNAVEQVMEAMHAPIFFEKYDVHG-EMSRVPPEVMESIRKNK 93
Query: 87 VGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRENTEG 146
V LKG TP G SLNV LRK+LD+FA++ ++PG+ TR N+D+V+IRENTEG
Sbjct: 94 VCLKGGLKTPVGG-GVSSLNVQLRKELDLFASLVNCFNLPGLPTRHENVDIVVIRENTEG 152
Query: 147 EYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGDGLF 206
EY+GLEHE VPGVVESLK++T+ SERIA++AF++A NNRK V AVHKANIMKL DGLF
Sbjct: 153 EYAGLEHEVVPGVVESLKVITKFCSERIAKYAFEYAYLNNRKKVTAVHKANIMKLADGLF 212
Query: 207 RNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALIGGP 266
+ E+ A +YP + IIVDN MQ VAKP QFDV+VTPNLYG+++ N + + GG
Sbjct: 213 LESCREV-AKKYPSITYNEIIVDNCCMQLVAKPEQFDVMVTPNLYGNLVANTAAGIAGGT 271
Query: 267 GLVPGANFGREYAVFEPGSR--HVGLD-IKGQNVANPTAMILSSTLMLRHLGLNAYADRI 323
G++PG N G ++AVFE G+ +VG D I +N ANP A++LSS +MLRHL ++ADR+
Sbjct: 272 GVMPGGNVGADHAVFEQGASAGNVGKDKIVLENKANPVALLLSSAMMLRHLQFPSFADRL 331
Query: 324 SKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKL 358
A VI+EGK T+D+GG+++T E +AVI KL
Sbjct: 332 ETAVKKVIAEGKCRTKDLGGTSTTQEVVDAVIAKL 366
>At4g35650 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 368
Score = 323 bits (827), Expect = 3e-88
Identities = 177/336 (52%), Positives = 230/336 (67%), Gaps = 8/336 (2%)
Query: 27 GGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENV-QRAVESLKRN 85
G TVTLIPGDG+G VT +V ++ E + P+ +E ++ G N V + +ES+KRN
Sbjct: 36 GAPRTVTLIPGDGIGPLVTGAVEQVMEAMHAPVHFERYEVLG--NMRKVPEEVIESVKRN 93
Query: 86 KVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRENTE 145
KV LKG TP G SLN+ LRK+LDIFA++ ++PG+ TR N+D+V+IRENTE
Sbjct: 94 KVCLKGGLATPVGG-GVSSLNMQLRKELDIFASLVNCINVPGLVTRHENVDIVVIRENTE 152
Query: 146 GEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGDGL 205
GEYSGLEHE VPGVVESLK++T+ SERIAR+AF++A NNRK V AVHKANIMKL DGL
Sbjct: 153 GEYSGLEHEVVPGVVESLKVITKFCSERIARYAFEYAYLNNRKKVTAVHKANIMKLADGL 212
Query: 206 FRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALIGG 265
F + E+ A Y + IIVDN MQ VAKP QFDV+VTPNLYG+++ N + + GG
Sbjct: 213 FLESCREV-AKHYSGITYNEIIVDNCCMQLVAKPEQFDVMVTPNLYGNLIANTAAGIAGG 271
Query: 266 PGLVPGANFGREYAVFEPGSR--HVGLD-IKGQNVANPTAMILSSTLMLRHLGLNAYADR 322
G++PG N G E+A+FE G+ +VG D + Q ANP A++LSS +MLRHL +ADR
Sbjct: 272 TGVMPGGNVGAEHAIFEQGASAGNVGNDKMVEQKKANPVALLLSSAMMLRHLRFPTFADR 331
Query: 323 ISKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKL 358
+ A VI EGK T+D+GG +T E +AVI L
Sbjct: 332 LETAVKQVIKEGKYRTKDLGGDCTTQEVVDAVIAAL 367
>CE16887 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 373
Score = 322 bits (826), Expect = 4e-88
Identities = 166/337 (49%), Positives = 232/337 (68%), Gaps = 1/337 (0%)
Query: 25 KYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENVQRAVESLKR 84
KYGGR+TV +PGDG+G E+ + IF + P+++E + +S ++ A+ +++R
Sbjct: 31 KYGGRHTVCALPGDGIGPEMIAHIRNIFSFCHAPVNFEEVQVSSSLLDGDMDAAMLAIER 90
Query: 85 NKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRENT 144
N V +KG T D S NV LR +LD++AN+ +IP V TR + ID+V+IRENT
Sbjct: 91 NGVAIKGNIETKHDDPQFNSRNVELRTKLDLYANILHCVTIPTVPTRHSGIDIVLIRENT 150
Query: 145 EGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGDG 204
EGEYSGLEHE+VPG+VES+KI+TR K ERI+R AF++A N RK V AVHKANI KLGDG
Sbjct: 151 EGEYSGLEHEAVPGIVESIKIVTREKIERISRMAFEYAKANGRKKVTAVHKANIQKLGDG 210
Query: 205 LFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALIG 264
LF V ++ + +Y ++ + +IVDNASMQ V+KP QFDV+V PNLYG+I+ NI L+G
Sbjct: 211 LFLKVVRDM-SEDYKDIKFEAMIVDNASMQLVSKPQQFDVMVMPNLYGNIISNIACGLVG 269
Query: 265 GPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNAYADRIS 324
GPGLV G N G +YAVFE G+R+ G + G+++ANPTA I +S MLR+LG + +A+ IS
Sbjct: 270 GPGLVSGMNLGDKYAVFETGTRNTGTSLAGKDIANPTAFIRASVDMLRYLGCHYHANIIS 329
Query: 325 KATYDVISEGKSTTRDIGGSASTSEFTNAVIEKLAKL 361
A + + E + T DIGG+ S S+ NA ++ + L
Sbjct: 330 DALWKALVEQRIHTADIGGNNSASDVINATLQNIKVL 366
>CE00970 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 380
Score = 321 bits (823), Expect = 9e-88
Identities = 165/326 (50%), Positives = 226/326 (68%), Gaps = 5/326 (1%)
Query: 25 KYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLEN-TENVQRAVESLK 83
+YGGR+ VT++PGDG+G E+ V +I P+D+E ++++ E+ +E++ A+ ++K
Sbjct: 47 RYGGRHNVTVLPGDGIGPEMLHHVERILSAVQAPVDFEVVNLTSKEDASEDLAEAITAIK 106
Query: 84 RNKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIREN 143
RN V LKG T D S N+ LR+QL+++ANV +IP V +R IDMVIIREN
Sbjct: 107 RNGVALKGNIETKFDNPSFVSRNLELRRQLNLYANVLHCSTIPTVPSRHTGIDMVIIREN 166
Query: 144 TEGEYSGLEHESV----PGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIM 199
TEGEYSG EHE+V P VVESLK++TR KSE+I RFAF FA K RK V AVHKANI
Sbjct: 167 TEGEYSGNEHEAVNAPHPRVVESLKVVTREKSEQITRFAFQFAKKYGRKKVTAVHKANIQ 226
Query: 200 KLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIG 259
KLGDGLF +I EYP+++ +IVDNASMQ V++P QFDV++ PNLYG+I+ NI
Sbjct: 227 KLGDGLFLKVATDIAKAEYPDIEFNAMIVDNASMQLVSRPQQFDVMLMPNLYGNIISNIA 286
Query: 260 SALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNAY 319
L+GGPGLV G N G +YAVFE G+R+ G + G+++ANPTA I ++ MLR LGL ++
Sbjct: 287 CGLVGGPGLVSGMNIGEDYAVFETGTRNTGTTLAGKDLANPTAFIRAAVDMLRFLGLQSH 346
Query: 320 ADRISKATYDVISEGKSTTRDIGGSA 345
AD IS + + + + + T DIGG++
Sbjct: 347 ADMISDSLFRTLVDKRIHTADIGGTS 372
>7301367 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 393
Score = 321 bits (823), Expect = 9e-88
Identities = 166/354 (46%), Positives = 234/354 (65%), Gaps = 6/354 (1%)
Query: 7 AAQKKSFATLAAEQLLPKKYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDI 66
A QKK T + +YGGR+ VT++PG G+G E+ V +IF PID+E IDI
Sbjct: 39 ALQKKVTGT----DIPSAQYGGRHAVTMLPGGGIGPELMGYVREIFRYCGAPIDFEVIDI 94
Query: 67 S-GLENTENVQRAVESLKRNKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSI 125
E +++ A+ S+KRN V LKG T + S NVA+R +LD++ NV KS
Sbjct: 95 DPSTEGNDDLDYAITSIKRNGVALKGNIETKSQSLTEVSRNVAIRNELDLYVNVVHCKSY 154
Query: 126 PGVKTRLNNIDMVIIRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKN 185
PG+ R ++ID+V+IR+NT+GEY+ LEHESVPG+VES+K++T +ER+AR+AF+FA +N
Sbjct: 155 PGIPARHHDIDVVLIRQNTDGEYAMLEHESVPGIVESMKVVTVENAERVARYAFEFARQN 214
Query: 186 NRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVL 245
NRK V +HKANIMKL DGLF N + +YPEL+ N+I+DN MQ+V+ PHQFDV+
Sbjct: 215 NRKKVTTIHKANIMKLSDGLFLEVANRV-HKDYPELEHNNMIIDNTCMQSVSNPHQFDVM 273
Query: 246 VTPNLYGSILGNIGSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMIL 305
NLYG+I+ N+ L+GG GL+ G N+G YA+FEPG+R+ G I G+N+ANP AMI
Sbjct: 274 NMTNLYGTIVSNVLCGLMGGAGLISGRNYGDHYAIFEPGTRNTGTAIAGKNIANPVAMIS 333
Query: 306 SSTLMLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKLA 359
+S ML HLG +A+ I +A Y I T DIGG+ S+++ +++ L+
Sbjct: 334 ASIDMLNHLGHKEHANVIQEAVYQTIVNDAIRTPDIGGTNSSTDVVENILKILS 387
>At2g17130 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 367
Score = 318 bits (815), Expect = 8e-87
Identities = 171/330 (51%), Positives = 232/330 (69%), Gaps = 6/330 (1%)
Query: 32 VTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENVQRAVESLKRNKVGLKG 91
VTLIPGDGVG VT++V ++ E + P+ +E ++ G + + +ES+K+NKV LKG
Sbjct: 40 VTLIPGDGVGPLVTNAVQQVMEAMHAPVYFEPFEVHG-DMKSLPEGLLESIKKNKVCLKG 98
Query: 92 IWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRENTEGEYSGL 151
TP G SLNV LRK+LD+FA++ ++PG+ +R N+D+V+IRENTEGEY+GL
Sbjct: 99 GLKTPVGG-GVSSLNVNLRKELDLFASLVNCFNLPGLASRHENVDIVVIRENTEGEYAGL 157
Query: 152 EHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGDGLFRNTVN 211
EHE VPGVVESLK++T+ SERIA++AF++A NNRK V AVHKANIMKL DGLF +
Sbjct: 158 EHEVVPGVVESLKVITKFCSERIAKYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCQ 217
Query: 212 EIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALIGGPGLVPG 271
E+ A +YP + IIVDN MQ VA+P QFDV+VTPNLYG+++ N + + GG G++PG
Sbjct: 218 EV-AKKYPSIAYNEIIVDNCCMQLVARPEQFDVMVTPNLYGNLVANTAAGIAGGTGVMPG 276
Query: 272 ANFGREYAVFEPGSR--HVGLD-IKGQNVANPTAMILSSTLMLRHLGLNAYADRISKATY 328
N G EYAVFE G+ +VG D + Q ANP A++LSS +MLRHL ++ADR+ A
Sbjct: 277 GNVGAEYAVFEQGASAGNVGKDTTEEQKNANPVALLLSSAMMLRHLQFPSFADRLETAVK 336
Query: 329 DVISEGKSTTRDIGGSASTSEFTNAVIEKL 358
VI+EG T D+GG+++T E +AVI L
Sbjct: 337 RVIAEGNCRTEDLGGNSTTQEVVDAVIANL 366
>7293593 [E] KOG0785 Isocitrate dehydrogenase alpha subunit
Length = 377
Score = 314 bits (804), Expect = 1e-85
Identities = 159/335 (47%), Positives = 226/335 (67%), Gaps = 7/335 (2%)
Query: 28 GRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENV----QRAVESLK 83
G VTLIPGDG+G E++ +V KIF N+PI+WE +D++ + + Q A++S+
Sbjct: 46 GTKKVTLIPGDGIGPEISAAVQKIFTAANVPIEWEAVDVTPVRGPDGKFGIPQAAIDSVN 105
Query: 84 RNKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIREN 143
NK+GLKG TP + GH SLN+ALRK+ +++ANV +S+ G KT +++D+V IREN
Sbjct: 106 TNKIGLKGPLMTPVGK-GHRSLNLALRKEFNLYANVRPCRSLEGYKTLYDDVDVVTIREN 164
Query: 144 TEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGD 203
TEGEYSG+EHE V GVV+S+K++T S+R+A +AF +A NNRK V VHKANIM++ D
Sbjct: 165 TEGEYSGIEHEIVDGVVQSIKLITEEASKRVAEYAFQYAKNNNRKKVTVVHKANIMRMSD 224
Query: 204 GLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALI 263
GLF V ++ A ++PE+ + +D + V P ++DVLV PNLYG IL ++ + L+
Sbjct: 225 GLFLRCVRDM-AQKFPEIQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLV 283
Query: 264 GGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNAYADRI 323
GG GL P N G A+FE DI G+++ANPTA++LS+ +MLRH+ LN YAD+I
Sbjct: 284 GGLGLTPSGNMGLNGALFE-SVHGTAPDIAGKDLANPTALLLSAVMMLRHMELNTYADKI 342
Query: 324 SKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKL 358
+A ++ I EGK T D+GG A SEFTN + KL
Sbjct: 343 ERAAFETIKEGKYLTGDLGGRAKCSEFTNEICAKL 377
>At5g03290 [E] KOG0785 Isocitrate dehydrogenase alpha subunit
Length = 372
Score = 304 bits (779), Expect = 1e-82
Identities = 159/333 (47%), Positives = 219/333 (65%), Gaps = 8/333 (2%)
Query: 31 TVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENVQ-----RAVESLKRN 85
T TL PGDG+G E+ +SV K+F +PI+WE + G E Q ++ES++RN
Sbjct: 43 TATLFPGDGIGPEIAESVKKVFTTAGVPIEWEEHYV-GTEIDPRTQSFLTWESLESVRRN 101
Query: 86 KVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRENTE 145
KVGLKG TP + GH SLN+ LRK+L+++ANV S+PG KTR +++D++ IRENTE
Sbjct: 102 KVGLKGPMATPIGK-GHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVDLITIRENTE 160
Query: 146 GEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGDGL 205
GEYSGLEH+ V GVVESLKI+TR S R+A +AF +A + R+ V A+HKANIM+ DGL
Sbjct: 161 GEYSGLEHQVVRGVVESLKIITRQASLRVAEYAFLYAKTHGRERVSAIHKANIMQKTDGL 220
Query: 206 FRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALIGG 265
F E+ A +YPE+ + +++DN M V P FDVLV PNLYG I+ ++ + L+GG
Sbjct: 221 FLKCCREV-AEKYPEITYEEVVIDNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLVGG 279
Query: 266 PGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNAYADRISK 325
GL P N G + DI G+N+ANPTA++LS +MLRHL N A++I
Sbjct: 280 LGLTPSCNIGEDGVALAEAVHGSAPDIAGKNLANPTALLLSGVMMLRHLKFNEQAEQIHS 339
Query: 326 ATYDVISEGKSTTRDIGGSASTSEFTNAVIEKL 358
A + I+EGK T D+GGS++T+EFT A+ + L
Sbjct: 340 AIINTIAEGKYRTADLGGSSTTTEFTKAICDHL 372
>At3g09805 [E] KOG0785 Isocitrate dehydrogenase alpha subunit
Length = 374
Score = 295 bits (754), Expect = 9e-80
Identities = 153/330 (46%), Positives = 217/330 (65%), Gaps = 6/330 (1%)
Query: 33 TLIPGDGVGKEVTDSVVKIFENENIPIDWET----IDISGLENTENVQRAVESLKRNKVG 88
TL PGDG+G E+ +SV ++F ++ IDW+ ++ N+ ++S+ +NKVG
Sbjct: 47 TLFPGDGIGPEIAESVKQVFTAADVVIDWDEQFVGTEVDPRTNSFLTWDNLQSVLKNKVG 106
Query: 89 LKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRENTEGEY 148
LKG TP + GH SLN+ LRK+L+++ANV S+PG KTR +++D++ IRENTEGEY
Sbjct: 107 LKGPMATPIGK-GHRSLNLTLRKELNLYANVRPCYSLPGYKTRYDDVDLITIRENTEGEY 165
Query: 149 SGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGDGLFRN 208
SGLEH+ V GVVESLKI+TR S R+A +AF +A + RK V A+HKANIM+ DGLF
Sbjct: 166 SGLEHQVVKGVVESLKIITRKASMRVAEYAFLYAKTHGRKKVSAIHKANIMQKTDGLFLQ 225
Query: 209 TVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALIGGPGL 268
+E+ A +YPE+ + +++DN M V P FDVLV PNLYG I+ ++ + L+GG GL
Sbjct: 226 CCDEVAA-KYPEIYYEKVVIDNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLVGGLGL 284
Query: 269 VPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNAYADRISKATY 328
P N G + DI G N+ANPTA++LS +MLRHL LN A++I A
Sbjct: 285 TPSMNIGEDGIALAEAVHGSAPDIAGMNLANPTALLLSGVMMLRHLKLNKQAEQIHSAII 344
Query: 329 DVISEGKSTTRDIGGSASTSEFTNAVIEKL 358
+ I+EGK T D+GGS++T++FT A+ + L
Sbjct: 345 NTIAEGKYRTADLGGSSTTTDFTKAICDHL 374
>CE10354 [E] KOG0785 Isocitrate dehydrogenase alpha subunit
Length = 374
Score = 293 bits (749), Expect = 3e-79
Identities = 161/371 (43%), Positives = 230/371 (61%), Gaps = 23/371 (6%)
Query: 10 KKSFATLAAEQLLPKKYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGL 69
KK+ +T+ Q + G VTLIPGDG+G E++ SV KIFE + PI W+ +D++ +
Sbjct: 7 KKASSTVG--QSIRYSSGDVRRVTLIPGDGIGPEISASVQKIFEAADAPIAWDPVDVTPV 64
Query: 70 ENTENV----QRAVESLKRNKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSI 125
+ + V R +E + NKVGLKG TP + GH SLN+A+RK+ ++ANV +S+
Sbjct: 65 KGRDGVFRIPSRCIELMHANKVGLKGPLETPIGK-GHRSLNLAVRKEFSLYANVRPCRSL 123
Query: 126 PGVKTRLNNIDMVIIRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKN 185
G KT +N+D+V IRENTEGEYSG+EHE VPGVV+S+K++T S +A FAF++A +N
Sbjct: 124 EGHKTLYDNVDVVTIRENTEGEYSGIEHEIVPGVVQSIKLITETASRNVASFAFEYARQN 183
Query: 186 NRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVL 245
RK V AVHKANIM+ DGLF + E A YP++ K +D + V P Q+DVL
Sbjct: 184 GRKVVTAVHKANIMRQSDGLFLSICREQAA-LYPDIKFKEAYLDTVCLNMVQDPSQYDVL 242
Query: 246 VTPNLYGSILGNIGSALIGGPGLVPGANFGREYAVFEP---------------GSRHVGL 290
V PNLYG IL ++ + L+GG G+ P N G+ AVF+
Sbjct: 243 VMPNLYGDILSDLCAGLVGGLGVTPSGNIGKGAAVFDEIQFFIQTKLTKFLYRSVHGTAP 302
Query: 291 DIKGQNVANPTAMILSSTLMLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEF 350
DI GQ+ ANPTA++LS+ +MLR++ L +A RI KA +D I++G++ T D+GG+ + S F
Sbjct: 303 DIAGQDKANPTALLLSAVMMLRYMNLPQHAARIEKAVFDAIADGRAKTGDLGGTGTCSSF 362
Query: 351 TNAVIEKLAKL 361
T V ++ L
Sbjct: 363 TADVCARVKDL 373
>SPBC902.05c [E] KOG0785 Isocitrate dehydrogenase alpha subunit
Length = 378
Score = 290 bits (743), Expect = 2e-78
Identities = 150/341 (43%), Positives = 225/341 (64%), Gaps = 9/341 (2%)
Query: 24 KKYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGL---ENTENVQRAVE 80
K G YTVT+I GDG+G E+ SV +IF+ +PI+WE + + + T A E
Sbjct: 40 KNANGNYTVTMIAGDGIGPEIAQSVERIFKAAKVPIEWERVKVYPILKNGTTTIPDDAKE 99
Query: 81 SLKRNKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVII 140
S+++NKV LKG TP + GH S+N+ LR+ +FANV SI G KT +N++ V+I
Sbjct: 100 SVRKNKVALKGPLATPIGK-GHVSMNLTLRRTFGLFANVRPCVSITGYKTPYDNVNTVLI 158
Query: 141 RENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMK 200
RENTEGEYSG+EHE +PGVV+S+K++TRA SER+ R+AF +A + + ++ VHKA IM+
Sbjct: 159 RENTEGEYSGIEHEVIPGVVQSIKLITRAASERVIRYAFQYARQTGKNNITVVHKATIMR 218
Query: 201 LGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFD--VLVTPNLYGSILGNI 258
+ DGLF E+ A EYP+++++ I+DNA ++ V P ++ V+V PNLYG I+ ++
Sbjct: 219 MADGLFLECAKEL-APEYPDIELREEILDNACLKIVTDPVPYNNTVMVMPNLYGDIVSDM 277
Query: 259 GSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNA 318
+ LIGG GL P N G + ++FE DI G+ +ANPTA++LSS +ML+H+ LN
Sbjct: 278 CAGLIGGLGLTPSGNIGNQASIFE-AVHGTAPDIAGKGLANPTALLLSSVMMLKHMNLND 336
Query: 319 YADRISKATYDVISEG-KSTTRDIGGSASTSEFTNAVIEKL 358
YA RI A +D ++ + T+D+GG ++ ++T+A+I KL
Sbjct: 337 YAKRIESAIFDTLANNPDARTKDLGGKSNNVQYTDAIISKL 377
>Hs5031777 [E] KOG0785 Isocitrate dehydrogenase alpha subunit
Length = 366
Score = 287 bits (734), Expect = 2e-77
Identities = 151/339 (44%), Positives = 213/339 (62%), Gaps = 6/339 (1%)
Query: 27 GGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENV----QRAVESL 82
GG TVTLIPGDG+G E++ +V+KIF+ PI WE +++ ++ A ES+
Sbjct: 29 GGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESM 88
Query: 83 KRNKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRE 142
+NK+GLKG TP GH S+N+ LRK D++ANV SI G KT ++++V IRE
Sbjct: 89 DKNKMGLKGPLKTPI-AAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRE 147
Query: 143 NTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLG 202
NTEGEYSG+EH V GVV+S+K++T S+RIA FAF++A N+R +V AVHKANIM++
Sbjct: 148 NTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMS 207
Query: 203 DGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSAL 262
DGLF E+ A ++ + +D + V P QFDVLV PNLYG IL ++ + L
Sbjct: 208 DGLFLQKCREV-AESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGL 266
Query: 263 IGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNAYADR 322
IGG G+ P N G DI G+++ANPTA++LS+ +MLRH+GL +A R
Sbjct: 267 IGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAR 326
Query: 323 ISKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKLAKL 361
I A + I +GKS T+D+GG+A S+FT + ++ L
Sbjct: 327 IEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDL 365
>YOR136w [E] KOG0785 Isocitrate dehydrogenase alpha subunit
Length = 369
Score = 286 bits (733), Expect = 2e-77
Identities = 159/343 (46%), Positives = 220/343 (63%), Gaps = 10/343 (2%)
Query: 23 PKKYGGRYTVTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGL---ENTENVQRAV 79
P G+YTV+ I GDG+G E++ SV KIF N+PI+WE+ D+S + T AV
Sbjct: 30 PNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAV 89
Query: 80 ESLKRNKVGLKGIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVI 139
+S+ +N V LKG TP + GH SLN+ LRK +FANV KSI G KT N+D+V+
Sbjct: 90 QSITKNLVALKGPLATPIGK-GHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVL 148
Query: 140 IRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIM 199
IRENTEGEYSG+EH PGVV+S+K++TR SER+ R+AF++A R V VHK+ I
Sbjct: 149 IRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQ 208
Query: 200 KLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQFD--VLVTPNLYGSILGN 257
+L DGLF N E+ + EYP+L ++ ++DN+ ++ V P + V V PNLYG IL +
Sbjct: 209 RLADGLFVNVAKEL-SKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSD 267
Query: 258 IGSALIGGP-GLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGL 316
+ S L G GL P AN G + ++FE DI GQ+ ANPTA++LSS +ML H+GL
Sbjct: 268 LNSGLSAGSLGLTPSANIGHKISIFE-AVHGSAPDIAGQDKANPTALLLSSVMMLNHMGL 326
Query: 317 NAYADRISKATYDVISEG-KSTTRDIGGSASTSEFTNAVIEKL 358
+AD+I A I+ G ++ T D+ G+A+TS FT AVI++L
Sbjct: 327 TNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369
>7291785 [E] KOG0785 Isocitrate dehydrogenase alpha subunit
Length = 391
Score = 207 bits (528), Expect = 1e-53
Identities = 120/328 (36%), Positives = 191/328 (57%), Gaps = 9/328 (2%)
Query: 32 VTLIPGDGVGKEVTDSVVKIFENENIPIDWETIDISGLENTENVQRAV-ESLKRNKVGLK 90
VTLI G+GVG+E+ D+V ++ PI+W+ D +++++V V +SL+ NKVG+K
Sbjct: 72 VTLINGEGVGRELMDAVQEVICAVKAPIEWDVHDEFKAKDSDDVSPEVLKSLRANKVGIK 131
Query: 91 GIWHTPADQTGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRENTEGEYSG 150
G P D H + RKQ FA V+L I G+ + + D+VIIR+ EG+YSG
Sbjct: 132 G----PVDSR-HWQRQI--RKQFAQFAYVSLCSHIEGLDSPYGDFDVVIIRDQMEGDYSG 184
Query: 151 LEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGDGLFRNTV 210
+EH VPGV++++K+ T A + RIA F F++A+KN RK + HKANIM++ DG F +
Sbjct: 185 IEHLVVPGVMQTIKVSTTAGAARIAEFVFNYAVKNKRKRITVAHKANIMRMTDGNFLEAM 244
Query: 211 NEIGANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALIGGPGLVP 270
++ + +D ++ + KPH+ DV+V+ ++YG +L I ++G PG+ P
Sbjct: 245 RAEADKHVDDVLFEERYLDTCILKILLKPHKCDVMVSSSMYGDVLRVIAGGMMGVPGICP 304
Query: 271 GANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNAYADRISKATYDV 330
G + VF+ + + G+++ANPT +LS+ LMLRH+ ++ AD++ A V
Sbjct: 305 GYSVSSLGTVFDCRMKACHA-LAGKDLANPTGPLLSAALMLRHVKMDKQADQVDCAIRKV 363
Query: 331 ISEGKSTTRDIGGSASTSEFTNAVIEKL 358
+ T D+GG A SEF AV + L
Sbjct: 364 YKDTDIRTPDVGGKAKCSEFVKAVCDCL 391
>YIL094c [E] KOG0785 Isocitrate dehydrogenase alpha subunit
Length = 371
Score = 182 bits (463), Expect = 5e-46
Identities = 128/350 (36%), Positives = 187/350 (52%), Gaps = 25/350 (7%)
Query: 31 TVTLIPGDGVGKEVTDSVVKIFENENIP--IDWETIDI-SGLENTENVQRA-----VESL 82
T+ LIPGDG+GKEV + ++ EN N + + ID+ +G + + +A V+ L
Sbjct: 25 TIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVKVL 84
Query: 83 KRNKVG-LKGIWHTPADQT-GHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVII 140
K G L G +P + G+ S VALR+++ +FANV KS+ G K + IDMVI+
Sbjct: 85 KEQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGEKGK--PIDMVIV 142
Query: 141 RENTEGEYSGLEHESVPG-----VVESLKIMTRAKSERIARFAFDFALKN----NRKSVC 191
RENTE Y +E + V ++ K ++ + RIA A D ALK + ++
Sbjct: 143 RENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGQATLT 202
Query: 192 AVHKANIMKLGDGLFRNTVNEI---GANEYPELDVKNIIVDNASMQAVAKPHQFDVLVTP 248
HK+N++ DGLFR E+ ++Y ++ IVD+ + +P FDV+V P
Sbjct: 203 VTHKSNVLSQSDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAP 262
Query: 249 NLYGSILGNIGSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTAMILSST 308
NLYG IL + +AL+G G+VP AN G E + EP DI G+ +ANP A I S+
Sbjct: 263 NLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CHGSAPDIAGKGIANPIATIRSTA 321
Query: 309 LMLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKL 358
LML LG N A I KA + EG T D+GG AST + + V+ +L
Sbjct: 322 LMLEFLGHNEAAQDIYKAVDANLREGSIKTPDLGGKASTQQVVDDVLSRL 371
>SPAC31G5.04 [E] KOG0785 Isocitrate dehydrogenase alpha subunit
Length = 362
Score = 174 bits (442), Expect = 1e-43
Identities = 128/363 (35%), Positives = 190/363 (52%), Gaps = 41/363 (11%)
Query: 29 RYTVTLIPGDGVGKEVTDSVVKIFEN---------ENIPID--WETIDISGLENTENVQR 77
R + LIP DG+GKEV + ++ EN + I +D W T + +G E R
Sbjct: 6 RIVLGLIPADGIGKEVVPAARRLMENLPAKHKLKFDFIDLDAGWGTFERTGKALPE---R 62
Query: 78 AVESLKRN-KVGLKGIWHTPADQT-GHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNI 135
VE LK L G +P + G+ S VALRK++ ++ANV KS+ G K + +
Sbjct: 63 TVERLKTECNAALFGAVQSPTHKVAGYSSPIVALRKKMGLYANVRPVKSLDGAKGK--PV 120
Query: 136 DMVIIRENTEGEYSGLEH--ESVPG--VVESLKIMTRAKSERIARFAFDFALK------- 184
D+VI+RENTE Y E ++ PG V E+++ ++ S +I + AF+ A
Sbjct: 121 DLVIVRENTECLYVKEERMVQNTPGKRVAEAIRRISEEASTKIGKMAFEIAKSRQKIRES 180
Query: 185 -----NNRKSVCAVHKANIMKLGDGLFRNTVNEIGANE--YPELDVKNIIVDNASMQAVA 237
+ + V +HK+N+M + DGLFR + + + Y ++V IVD+ +
Sbjct: 181 GTYSIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYASINVDEQIVDSMVYRLFR 240
Query: 238 KPHQFDVLVTPNLYGSILGNIGSALIGGPGLVPGANFGREYAVFEP--GSRHVGLDIKGQ 295
+P FDV+V PNLYG IL + ++LIG GLVP AN G + + EP GS DI G+
Sbjct: 241 EPECFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGDNFVMSEPVHGS---APDIAGR 297
Query: 296 NVANPTAMILSSTLMLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVI 355
+ANP A S LML +G A I A V++EGK T D+GG + T+E T+AV+
Sbjct: 298 GIANPVATFRSVALMLEFMGHQDAAADIYTAVDKVLTEGKVLTPDLGGKSGTNEITDAVL 357
Query: 356 EKL 358
+
Sbjct: 358 ANI 360
>At1g32480 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 294
Score = 159 bits (402), Expect = 6e-39
Identities = 116/322 (36%), Positives = 172/322 (53%), Gaps = 39/322 (12%)
Query: 40 VGKEVTDSVVKIFENENIPIDWETIDISGLENTENVQRAVESLKRNKVGLKGIWHTPADQ 99
+ VT++V ++ + P+ +ET I G V+S+++NKV L G
Sbjct: 8 IDSNVTNAVHQVMDAMQAPVYFETYIIKGKNMNHLTWEVVDSIRKNKVCLNG-------- 59
Query: 100 TGHGSLNVALRKQLDIFANVALFKSIPGVKTRLNNIDMVIIRENTEGEYSGLEHESVPGV 159
+ SL RK+LD+FA++ ++ G +R N+D+V+IRENTEGEY+G EHE VPGV
Sbjct: 60 RVNNSLCGGARKELDLFASLVDCFNLNGQPSRHENVDIVVIRENTEGEYAGREHEVVPGV 119
Query: 160 VESLKI-MTRAKSERIARFAFDFALKNNRKSVCAVH-KANIMKLGDGLFRNTVNEIGANE 217
+ES ++ MT+ S+RIA++AF++A + RK V AVH KL D F + E+ A
Sbjct: 120 IESFQVTMTKFWSDRIAKYAFEYAHFSKRKKVTAVHNNGKYEKLADAFFLESCQEV-AKM 178
Query: 218 YPELDVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALIGGPGLVPGANFGRE 277
YP + I + +A+ + L +I+ NI S + GG +FG +
Sbjct: 179 YPNITYNEIA--SRETRAIRRHSNSKSL------WAIIANIASGVAGG-------SFGDD 223
Query: 278 YAVFEP-GSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNAYADRISKATYDVISEGKS 336
YA+FE GS VG N NP A++ SS +MLRHL L +ADR+ A VISEGK
Sbjct: 224 YAIFEQVGS--VG------NHKNPVALLFSSVMMLRHLLLPLFADRLKTAVTRVISEGKC 275
Query: 337 TTRDIGGSASTSEFTNAVIEKL 358
+ +T E ++VI L
Sbjct: 276 G----NSNTTTQEVVDSVIANL 293
>At1g31180 [E] KOG0786 3-isopropylmalate dehydrogenase
Length = 404
Score = 140 bits (354), Expect = 2e-33
Identities = 110/340 (32%), Positives = 174/340 (50%), Gaps = 39/340 (11%)
Query: 29 RYTVTLIPGDGVGKEVTDSVVKI-----------FENENIPIDWETIDISGLENTENVQR 77
RY +TL+PGDG+G EV + F+ + +P +D+ G+ E
Sbjct: 43 RYNITLLPGDGIGPEVISVAKNVLQKAGFLQGLEFDFQEMPFGGAALDLVGVPLPEETST 102
Query: 78 AVESLKRNKVGLKGIWHTPADQTG----HGSLNVALRKQLDIFANVALFKSIPGV----- 128
A + +G G + ++ G LN+ R+ L++FAN+ +P +
Sbjct: 103 AAKQSDAILLGAIGGYKWDKNEKHLRPEMGLLNI--RRDLNVFANLRPATVLPQLVDAST 160
Query: 129 --KTRLNNIDMVIIRENTEGEYSGLE-----HESVPGVVESLKIMTRAKSERIARFAFDF 181
K +DM+I+RE T G Y G +E+ V + +I + +RIAR AF+
Sbjct: 161 LKKEVAQGVDMMIVRELTGGIYFGEPRGITINENGEEVGFNTEIYAAHEIDRIARVAFET 220
Query: 182 ALKNNRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQ 241
A K K +C+V KAN++ L+R V + A+EYP++++ ++ VDNA+MQ V P Q
Sbjct: 221 ARKRRGK-LCSVDKANVLDASI-LWRKRVTAL-ASEYPDVELSHMYVDNAAMQLVRDPKQ 277
Query: 242 FDVLVTPNLYGSILGNIGSALIGGPGLVPGANFGRE-YAVFEP--GSRHVGLDIKGQNVA 298
FD +VT N++G IL + S + G G++P A+ G +FEP GS DI GQ+ A
Sbjct: 278 FDTIVTNNIFGDILSDEASMITGSIGMLPSASLGESGPGLFEPIHGS---APDIAGQDKA 334
Query: 299 NPTAMILSSTLMLRH-LGLNAYADRISKATYDVISEGKST 337
NP A ILS+ ++L++ LG A I A D +++G T
Sbjct: 335 NPLATILSAAMLLKYGLGEEKAAKMIEDAVVDALNKGFRT 374
>At5g14200 [E] KOG0786 3-isopropylmalate dehydrogenase
Length = 409
Score = 139 bits (351), Expect = 5e-33
Identities = 110/339 (32%), Positives = 174/339 (50%), Gaps = 37/339 (10%)
Query: 29 RYTVTLIPGDGVGKEVTDSVVKI-----------FENENIPIDWETIDISGLENTENVQR 77
RY + L+PGDG+G EV + F+ + +P+ +D+ G+ E
Sbjct: 46 RYNIALLPGDGIGPEVISVAKNVLQKAGSLEGLEFDFKEMPVGGAALDLVGVPLPEETFT 105
Query: 78 AVESLKRNKVGLKGIWHTPADQTGHGSLNVAL---RKQLDIFANVALFKSIPGV------ 128
A + +G G + ++ H +AL R+ L +FAN+ +P +
Sbjct: 106 AAKLSDAILLGAIGGYKWDKNEK-HLRPEMALFYLRRDLKVFANLRPATVLPQLVDASTL 164
Query: 129 -KTRLNNIDMVIIRENTEGEYSGLE-----HESVPGVVESLKIMTRAKSERIARFAFDFA 182
K +DM+I+RE T G Y G +E+ V S +I + +RIAR AF+ A
Sbjct: 165 KKEVAEGVDMMIVRELTGGIYFGEPRGITINENGEEVGVSTEIYAAHEIDRIARVAFETA 224
Query: 183 LKNNRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQF 242
K K +C+V KAN++ L+R V + A+EYP++++ ++ VDNA+MQ + P QF
Sbjct: 225 RKRRGK-LCSVDKANVLDASI-LWRKRVTAL-ASEYPDVELSHMYVDNAAMQLIRDPKQF 281
Query: 243 DVLVTPNLYGSILGNIGSALIGGPGLVPGANFGRE-YAVFEP--GSRHVGLDIKGQNVAN 299
D +VT N++G IL + S + G G++P A+ G +FEP GS DI GQ+ AN
Sbjct: 282 DTIVTNNIFGDILSDEASMITGSIGMLPSASLGESGPGLFEPIHGS---APDIAGQDKAN 338
Query: 300 PTAMILSSTLMLRH-LGLNAYADRISKATYDVISEGKST 337
P A ILS+ ++L++ LG A RI A D +++G T
Sbjct: 339 PLATILSAAMLLKYGLGEEKAAKRIEDAVVDALNKGFRT 377
>At1g80560 [E] KOG0786 3-isopropylmalate dehydrogenase
Length = 405
Score = 134 bits (336), Expect = 3e-31
Identities = 109/360 (30%), Positives = 173/360 (47%), Gaps = 35/360 (9%)
Query: 7 AAQKKSFATLAAEQLLPKKYGGRYTVTLIPGDGVGKEVTDSVVKI-----------FENE 55
A K+S A + RYT+TL+PGDG+G EV + F
Sbjct: 20 AVSKQSLAPFRVRCAVASPGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFR 79
Query: 56 NIPIDWETIDISGLENTENVQRAVESLKRNKVGLKG--IWHTPADQTGHGSLNVALRKQL 113
+PI +D+ G+ E A + +G G W + +R L
Sbjct: 80 EMPIGGAALDLVGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAAL 139
Query: 114 DIFANVALFKSIPGV-------KTRLNNIDMVIIRENTEGEYSG-----LEHESVPGVVE 161
+FAN+ +P + + +D++++RE T G Y G +E+ V
Sbjct: 140 KVFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGF 199
Query: 162 SLKIMTRAKSERIARFAFDFALKNNRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPEL 221
+ ++ + +RIAR AF+ A K K +C+V KAN+++ L+R V + A+EYP++
Sbjct: 200 NTEVYAAHEIDRIARVAFETARKRRGK-LCSVDKANVLEASI-LWRKRVTAL-ASEYPDV 256
Query: 222 DVKNIIVDNASMQAVAKPHQFDVLVTPNLYGSILGNIGSALIGGPGLVPGANFGRE-YAV 280
++ ++ VDNA+MQ V P QFD +VT N++G IL + S + G G++P A+ +
Sbjct: 257 ELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGL 316
Query: 281 FEP--GSRHVGLDIKGQNVANPTAMILSSTLMLRH-LGLNAYADRISKATYDVISEGKST 337
FEP GS DI GQ+ ANP A ILS+ ++L++ LG A RI A ++ G T
Sbjct: 317 FEPIHGS---APDIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRT 373
>YCL018w [E] KOG0786 3-isopropylmalate dehydrogenase
Length = 364
Score = 117 bits (292), Expect = 3e-26
Identities = 104/362 (28%), Positives = 171/362 (46%), Gaps = 38/362 (10%)
Query: 32 VTLIPGDGVGKEVTDSVVKIFE-----NENIPIDWET-------IDISGLENTENVQRAV 79
+ ++PGD VG+E+T +K+ + N+ D+E ID +G+ + A
Sbjct: 7 IVVLPGDHVGQEITAEAIKVLKAISDVRSNVKFDFENHLIGGAAIDATGVPLPDEALEAS 66
Query: 80 ESLKRNKVGLKG--IWHTPADQTGHGSLNVALRKQLDIFANV--------ALFKSIPGVK 129
+ +G G W T + + G L + RK+L ++AN+ +L P
Sbjct: 67 KKADAVLLGAVGGPKWGTGSVRPEQGLLKI--RKELQLYANLRPCNFASDSLLDLSPIKP 124
Query: 130 TRLNNIDMVIIRENTEGEYSGLEHESV-PGVVESLKIMTRAKSERIARFAFDFALKNNRK 188
D V++RE G Y G E GV + T + +RI R A AL++
Sbjct: 125 QFAKGTDFVVVRELVGGIYFGKRKEDDGDGVAWDSEQYTVPEVQRITRMAAFMALQHEPP 184
Query: 189 -SVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKP-HQFDVLV 246
+ ++ KAN++ L+R TV E NE+P L V++ ++D+A+M V P H +++
Sbjct: 185 LPIWSLDKANVLA-SSRLWRKTVEETIKNEFPTLKVQHQLIDSAAMILVKNPTHLNGIII 243
Query: 247 TPNLYGSILGNIGSALIGGPGLVPGANF------GREYAVFEPGSRHVGLDIKGQNVANP 300
T N++G I+ + S + G GL+P A+ + ++EP H +N NP
Sbjct: 244 TSNMFGDIISDEASVIPGSLGLLPSASLASLPDKNTAFGLYEP--CHGSAPDLPKNKVNP 301
Query: 301 TAMILSSTLMLR-HLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVIEKLA 359
A ILS+ +ML+ L L I A V+ G T D+GGS ST+E +AV E++
Sbjct: 302 IATILSAAMMLKLSLNLPEEGKAIEDAVKKVLDAG-IRTGDLGGSNSTTEVGDAVAEEVK 360
Query: 360 KL 361
K+
Sbjct: 361 KI 362
>7302952 [E] KOG0784 Isocitrate dehydrogenase gamma subunit
Length = 368
Score = 114 bits (285), Expect = 2e-25
Identities = 96/350 (27%), Positives = 166/350 (47%), Gaps = 23/350 (6%)
Query: 7 AAQKKSFATLAAEQLLPK-KYGGRYTVTLIPGDGV-GKEVTDSVVKIFENENIPIDWETI 64
AA K A +LPK KYGG TV+L+ G + G++ V + + +P++ + I
Sbjct: 20 AAYAKGDARADPVNVLPKSKYGGINTVSLVTGTTIIGQQGAQFVSSLLSSSRVPVEVQVI 79
Query: 65 DISGLENTENVQRAVESLKRNKVGLKGIWHTPADQTGHGSLNVALR--KQLDIFANVALF 122
+ +G ++ S+ RN+ + H +Q + AL+ LD++
Sbjct: 80 E-AGQDD-----EYFHSVLRNRTAV----HVD-NQADAEAKQKALKICNDLDLYVFKTRT 128
Query: 123 KSIPGVKTRLNNIDMVIIRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFA 182
+S PG K R +D+ +I +N G ++ LE+ V GVVE+L ++++ +++ R+AF A
Sbjct: 129 RSFPGFKCRFPGVDIQLIGQNNMGIFNELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAA 188
Query: 183 LKNNRKSVCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVAKPHQF 242
K RK V ++KA + DG + + L+++ + V+ A + + +P F
Sbjct: 189 AKAGRKRVTLINKAKEWPISDGSLVEAAQRLHCHYKDCLELELMEVEEAISRLMTEPTYF 248
Query: 243 DVLVTPNLYGSILGNIGSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNVANPTA 302
D L Y + L I S + GG L G +AVF+P + L N AN +A
Sbjct: 249 DCLFASERYATFLSAICSGVCGGANLFSAVEIGDHHAVFKPLQTKLSL----TNYANLSA 304
Query: 303 MILSSTL--MLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEF 350
+ ST+ + +HLG + AD + + EG T++ GG T E+
Sbjct: 305 YGIVSTIVDLFQHLGHDKCADALWCELKRTMDEG-IRTKEFGGQ-DTGEY 352
>SPBC1A4.02c [E] KOG0786 3-isopropylmalate dehydrogenase
Length = 220
Score = 100 bits (248), Expect = 4e-21
Identities = 77/208 (37%), Positives = 117/208 (56%), Gaps = 24/208 (11%)
Query: 173 RIARFAFDFALKNNRKS-VCAVHKANIMKLGDGLFRNTVNEIGANEYPELDVKNIIVDNA 231
RIAR A A +N + V + KAN++ L+R TV +I EYP L +KN ++D+A
Sbjct: 17 RIARLAAWLAETSNPPAPVTLLDKANVLATSR-LWRKTVAKIFKEEYPHLTLKNQLIDSA 75
Query: 232 SMQAVAKPHQFD-VLVTPNLYGSILGNIGSALIGGPGLVPGANFG--------REYAVFE 282
+M V P + V++T NL+G I+ + S + G GL+P A+ + + + E
Sbjct: 76 AMLLVKSPRTLNGVVLTDNLFGDIISDEASVIPGSLGLLPSASLSGVVGKSEEKVHCLVE 135
Query: 283 P--GSRHVGLDIKGQNVANPTAMILSSTLMLRHLGLNA--YADRISKATYDVISE----G 334
P GS DI G+ + NP ILS++L+LR+ GLNA A+ I A V+ + G
Sbjct: 136 PIHGS---APDIAGKGIVNPVGTILSASLLLRY-GLNAPKEAEAIEAAVRKVLDDTSIGG 191
Query: 335 KST-TRDIGGSASTSEFTNAVIEKLAKL 361
+ TRD+GG AST++ T AV+E+L K+
Sbjct: 192 RGLYTRDLGGEASTADITKAVVEELEKI 219
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.135 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,354,824
Number of Sequences: 60738
Number of extensions: 860379
Number of successful extensions: 2118
Number of sequences better than 1.0e-05: 29
Number of HSP's better than 0.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1994
Number of HSP's gapped (non-prelim): 30
length of query: 361
length of database: 30,389,216
effective HSP length: 108
effective length of query: 253
effective length of database: 23,829,512
effective search space: 6028866536
effective search space used: 6028866536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)