ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI1153 good E KOG2964 Amino acid transport and metabolism Arginase family protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI1153 404537 403197 -447
(447 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPAC11D3.09 [E] KOG2964 Arginase family protein 293 3e-79
SPAPB24D3.03 [E] KOG2964 Arginase family protein 257 2e-68
SPBC8E4.03 [E] KOG2964 Arginase family protein 249 6e-66
Hs13376095 [E] KOG2964 Arginase family protein 130 3e-30
At4g08870 [E] KOG2964 Arginase family protein 82 2e-15
At4g08900 [E] KOG2964 Arginase family protein 78 3e-14
Hs4502215 [E] KOG2965 Arginase 53 8e-07
>SPAC11D3.09 [E] KOG2964 Arginase family protein
Length = 394
Score = 293 bits (751), Expect = 3e-79
Identities = 159/380 (41%), Positives = 223/380 (57%), Gaps = 23/380 (6%)
Query: 71 VAAARPLIKVHPEETDEEFRGMCSFYNDHENEYPEDDFEDDLLQFTGIVSFAHTPIAQCF 130
+A A L + HP+ ++ ++D +P D F+GI +F P +C
Sbjct: 11 LAGAAQLAQAHPKIFEQSRANAVETFDD---AFPGDGETQADSVFSGIATFGRLPYWKCL 67
Query: 131 RNTSLEMDIAIVGAPFDTSVSYRPGARFGPNGIRQGSRRLGNGISPVRGFPGSKL-RKLD 189
+ S DIA +GAPFDT SYRPGARFGP+GIR+GSRRL + G + + +
Sbjct: 68 NDKSQSFDIAFLGAPFDTGTSYRPGARFGPSGIREGSRRLNL-------YGGYNVPMETN 120
Query: 190 PYHSGYKIVDCGDIPMTPFDNKLALNQLYRGQRALHNHSSLVHKEQP---------PKLI 240
P+++ KIVDCGDIP+T +DN +A+ Q+ G L + E+ P++I
Sbjct: 121 PFNNWAKIVDCGDIPLTSYDNAVAIKQIENGHFELLTRKPTSYSEKDGYALDGSVLPRVI 180
Query: 241 TLGGDHTITLMALRSAYEHYGKVSVIHFDSHLDTWDPKVLGGNISKRAGLNHGTFLHFAH 300
TLGGDHTI L LRS YG VS+IHFDSHLD+W PKV GG S +NHGT+ + A
Sbjct: 181 TLGGDHTIVLPILRSVSRAYGPVSIIHFDSHLDSWKPKVFGGGKSSVGSINHGTYFYHAS 240
Query: 301 ENGYLQDDKNIHVGIRAPYIAPGFYDEDHDYECGFEKIVARDLDIISLKEVVSAIKKRVG 360
+ G + +D NIH GIR G D D+D +CGFE I AR++D I + ++ I+ RVG
Sbjct: 241 QEGLVSNDSNIHAGIRT--TLSGLSDYDNDADCGFEIIEAREIDTIGIDAIIKRIRDRVG 298
Query: 361 DGPVYISVDIDVVDLASAXXXXXXXXXXXXSRELLTILDGLEGLNIIGADIVEVLPAFDT 420
DG Y+S+DIDV+D A A +REL TIL GL+G+ ++GADIVEV PA+D
Sbjct: 299 DGIAYLSIDIDVLDPAYAPATGTPESAGWTTRELRTILRGLDGIKLVGADIVEVAPAYDF 358
Query: 421 NGDITTIIAAQVVDSILGLM 440
++TT+ AA ++ ++ +M
Sbjct: 359 -AEVTTLAAADILFEVMSIM 377
>SPAPB24D3.03 [E] KOG2964 Arginase family protein
Length = 385
Score = 257 bits (657), Expect = 2e-68
Identities = 139/336 (41%), Positives = 203/336 (60%), Gaps = 19/336 (5%)
Query: 115 FTGIVSFAHTPIAQCFRNTSLEMDIAIVGAPFDTSVSYRPGARFGPNGIRQGSRRLGNGI 174
++GI +F +C S + DIA +G PFDT SYRPGARFGP+ +R+GSRR+
Sbjct: 40 YSGIATFGRLENVECLSKRSEDFDIAFIGMPFDTGTSYRPGARFGPSSLREGSRRINTKY 99
Query: 175 SPVRGFPGSKLRKLDPYHSGYKIVDCGDIPMTPFDNKLALNQLY--------RGQRALHN 226
V + +++P+ S K+VDCGDIP+T +D A++QL R + +
Sbjct: 100 GAV-----NVPLEINPFKSWAKLVDCGDIPVTTYDILKAMDQLESAYFQLIARKPSSFTD 154
Query: 227 HSSLVHKEQP-PKLITLGGDHTITLMALRSAYEHYGK-VSVIHFDSHLDTWDPKVLGGNI 284
H + P++++LGGDHTI L LR+ + YG+ +SVIHFDSHLDTW P ++G
Sbjct: 155 HDGFAKNDTVLPRVLSLGGDHTIVLPILRALHRVYGQPISVIHFDSHLDTWAPGLIGDG- 213
Query: 285 SKRAGLNHGTFLHFAHENGYLQDDKNIHVGIRAPYIAPGFYDEDHDYECGFEKIVARDLD 344
+ G+NHG++ +FA + G + D NIH GIR P + F D D D +CGF+ I AR++D
Sbjct: 214 DEADGINHGSYFYFASQEGIMSKDANIHAGIRTPISS--FSDYDDDVDCGFKIIEAREID 271
Query: 345 IISLKEVVSAIKKRVGDGPVYISVDIDVVDLASAXXXXXXXXXXXXSRELLTILDGLEGL 404
+ + +V I+ RVGD VY+S+DIDV+D A A SRE+ IL GL+GL
Sbjct: 272 DLGIDGIVKKIRDRVGDNLVYLSIDIDVLDPAFAPATGTPETGGWSSREMRAILRGLQGL 331
Query: 405 NIIGADIVEVLPAFDTNGDITTIIAAQVVDSILGLM 440
+GAD+VEV PA+D +IT++ AQ++ I+ +M
Sbjct: 332 KFVGADLVEVAPAYDV-AEITSLAGAQLLFDIVSMM 366
>SPBC8E4.03 [E] KOG2964 Arginase family protein
Length = 413
Score = 249 bits (636), Expect = 6e-66
Identities = 146/364 (40%), Positives = 203/364 (55%), Gaps = 32/364 (8%)
Query: 103 YPEDDFEDDL---------LQFTGIVSFAHTPIAQCFRNTSLEMDIAIVGAPFDTSVSYR 153
Y +D +DD Q++GI +FAH P +C S + DIAI+G PFDT+VS+R
Sbjct: 46 YEDDSLDDDTWRSKRWEFDYQYSGISTFAHLPHVRCLVEQSEDFDIAIIGVPFDTAVSHR 105
Query: 154 PGARFGPNGIRQGSRRLGNGISPVRGFPGSKLRKLDPYHSGYKIVDCGDIPMTPFDNKLA 213
PGARFGP GIR S R +RGF S ++PY S KI+DCGDIP++ +DN+LA
Sbjct: 106 PGARFGPKGIRSASSRQ----MAIRGFNPSL--NVNPYESWAKILDCGDIPVSSYDNQLA 159
Query: 214 LNQLYRGQRALHNHSSLVHKEQP--------------PKLITLGGDHTITLMALRSAYEH 259
+ Q+ G L + + P+LITLGGDH+I L +LR+
Sbjct: 160 VRQMTEGYIDLLSRKATASPASNNLKTAGLAKDGIFHPRLITLGGDHSIGLASLRALGHF 219
Query: 260 YGKVSVIHFDSHLDTWDPKVLGGNI--SKRAGLNHGTFLHFAHENGYLQDDKNIHVGIRA 317
YG VSVIHFDSHLDTW+PK + S RA HGT A + G + + +IH G+R
Sbjct: 220 YGNVSVIHFDSHLDTWNPKRYYPSYWHSDRADFTHGTMFWMASKEGLINNGTSIHAGLRT 279
Query: 318 PYIAPGFYDEDHDYECGFEKIVARDLDIISLKEVVSAIKKRVGDGPVYISVDIDVVDLAS 377
+YD + D GF I A+++D I + +V IK+ VGD VY+S+DIDVVD
Sbjct: 280 RLSGTDYYDYEEDNRVGFTFIEAQEIDEIGVNGIVERIKQVVGDTLVYLSIDIDVVDPGL 339
Query: 378 AXXXXXXXXXXXXSRELLTILDGLEG-LNIIGADIVEVLPAFDTNGDITTIIAAQVVDSI 436
A +RE+ +IL L+G LN++GA++VEV P +D + T++ A+ + I
Sbjct: 340 APGTGTPETGGWTTREMKSILRKLDGHLNLVGAEVVEVSPPYDDRAESTSLAASDFIFEI 399
Query: 437 LGLM 440
L M
Sbjct: 400 LSSM 403
>Hs13376095 [E] KOG2964 Arginase family protein
Length = 352
Score = 130 bits (328), Expect = 3e-30
Identities = 101/348 (29%), Positives = 165/348 (47%), Gaps = 40/348 (11%)
Query: 101 NEYPEDDFEDDLLQFTGIVSFAHTPIAQCFRNTSLE-MDIAIVGAPFDTSVSYRPGARFG 159
N+ P +F + + G+ S P+ TS E +D A +G P DT S RPGARFG
Sbjct: 42 NQPPSPEF---VARPVGVCSMMRLPV-----QTSPEGLDAAFIGVPLDTGTSNRPGARFG 93
Query: 160 PNGIRQGSRRLGNGISPVRGFPGSKLRKLDPYHSGYKIVDCGDIPMTPFDNKLALNQLYR 219
P IR+ S L ++P G P+ S + D GD+ + ++ + + ++
Sbjct: 94 PRRIREESVMLRT-VNPSTGAL--------PFQS-LMVADLGDVNVNLYNLQDSCRRIQE 143
Query: 220 GQRALHNHSSLVHKEQPPKLITLGGDHTITLMALRSAYEHYGKVSVIHFDSHLDTWDPKV 279
+ + +TLGGDHTIT L++ + +G V ++H D+H DT D K
Sbjct: 144 ACEKIVAAGCIP--------LTLGGDHTITYPILQAMAKKHGPVGLLHVDAHTDTTD-KA 194
Query: 280 LGGNISKRAGLNHGTFLHFAHENGYLQDDKNIHVGIR--APYIAPGFYDEDHDYECGFEK 337
LG L HG + G L + + +GIR + + P Y+ GF
Sbjct: 195 LGEK------LYHGAPFRRCVDEGLLDCKRVVQIGIRGSSTTLDPYRYNRSQ----GFRV 244
Query: 338 IVARDLDIISLKEVVSAIKKRVGDGPVYISVDIDVVDLASAXXXXXXXXXXXXSRELLTI 397
++A D + SL ++ +++++G P+YIS DID +D A A + L I
Sbjct: 245 VLAEDCWMKSLVPLMGEVRQQMGGKPIYISFDIDALDPAYAPGTGTPEIAGLTPSQALEI 304
Query: 398 LDGLEGLNIIGADIVEVLPAFDTNGDITTIIAAQVVDSILGLMTVDSV 445
+ G +GLN++G D+VEV P +D +G+ + A + + + L V +V
Sbjct: 305 IRGCQGLNVMGCDLVEVSPPYDLSGNTALLAANLLFEMLCALPKVTTV 352
>At4g08870 [E] KOG2964 Arginase family protein
Length = 344
Score = 81.6 bits (200), Expect = 2e-15
Identities = 79/303 (26%), Positives = 139/303 (45%), Gaps = 28/303 (9%)
Query: 140 AIVGAPFDTSVSYRPGARFGPNGIRQGSRRLGNGISPVRGFPGSKLRKLDPYHSGYKIVD 199
A++G P + S+ G P +R+ + G + G +L+ DP + D
Sbjct: 68 ALLGVPLGHNSSFLEGPALAPPHVREA---IWCGSTNSTTEEGKELK--DPR----VLSD 118
Query: 200 CGDIPMTPFDNKLALNQLYRGQRALHNHSSLVHKEQPPKLITLGGDHTITLMALRSAYEH 259
GDIP+ ++ ++ R + + LV +E+P + + +GGDH+I+ +R+ E
Sbjct: 119 VGDIPVQEI-REMGVDD-DRLMKVVSESVKLVMEEEPLRPLVIGGDHSISYPVVRAVSEK 176
Query: 260 YG-KVSVIHFDSHLDTWDPKVLGGNISKRAGLNHGTFLHFAHENGYLQDDKNIHVGIRAP 318
G V ++H D+H D +D GN +H + E GY + + + VGIR+
Sbjct: 177 LGGPVDILHLDAHPDIYDR--FEGNY-----YSHASSFARIMEGGYAR--RLLQVGIRSI 227
Query: 319 YIAPGFYDEDHDYECGFEKIVARDLDIISLKEVVSAIKKRVGDGPVYISVDIDVVDLASA 378
+ G E+ R ++++ +K G VYIS+D+D +D A
Sbjct: 228 ----NKEGREQGKRFGVEQYEMRTFS--KDRQMLENLKLGEGVKGVYISIDVDCLDPGFA 281
Query: 379 XXXXXXXXXXXXSRELLTILDGLEGLNIIGADIVEVLPAFDTNGDITTIIAAQVVDSILG 438
R++L IL L+G +++GAD+VE P DT D+T ++AA+ V +
Sbjct: 282 HGVSHFEPGGLSFRDVLNILHNLQG-DLVGADVVEYNPQRDTADDMTAMVAAKFVRELAA 340
Query: 439 LMT 441
M+
Sbjct: 341 KMS 343
>At4g08900 [E] KOG2964 Arginase family protein
Length = 342
Score = 77.8 bits (190), Expect = 3e-14
Identities = 78/295 (26%), Positives = 133/295 (44%), Gaps = 28/295 (9%)
Query: 140 AIVGAPFDTSVSYRPGARFGPNGIRQGSRRLGNGISPVRGFPGSKLRKLDPYHSGYKIVD 199
+++G P + S+ G F P IR+ + G + G +L+ DP + D
Sbjct: 66 SLLGVPLGHNSSFLQGPAFAPPRIREA---IWCGSTNSATEEGKELK--DPR----VLTD 116
Query: 200 CGDIPMTPFDNKLALNQLYRGQRALHNHSSLVHKEQPPKLITLGGDHTITLMALRSAYEH 259
GD+P+ + + R + LV +E+P + + LGGDH+I+ +R+ E
Sbjct: 117 VGDVPVQEIRDCGVDDD--RLMNVISESVKLVMEEEPLRPLVLGGDHSISYPVVRAVSEK 174
Query: 260 Y-GKVSVIHFDSHLDTWDPKVLGGNISKRAGLNHGTFLHFAHENGYLQDDKNIHVGIRAP 318
G V ++H D+H D +D GN +H + E GY + + + VGIR
Sbjct: 175 LGGPVDILHLDAHPDIYD--CFEGN-----KYSHASSFARIMEGGYAR--RLLQVGIR-- 223
Query: 319 YIAPGFYDEDHDYECGFEKIVARDLDIISLKEVVSAIKKRVGDGPVYISVDIDVVDLASA 378
+ + G E+ R + ++ +K G VYIS+D+D +D A A
Sbjct: 224 --SINQEGREQGKRFGVEQYEMRTFS--KDRPMLENLKLGEGVKGVYISIDVDCLDPAFA 279
Query: 379 XXXXXXXXXXXXSRELLTILDGLEGLNIIGADIVEVLPAFDTNGDITTIIAAQVV 433
R++L IL L+ +++GAD+VE P DT +T ++AA++V
Sbjct: 280 PGVSHIEPGGLSFRDVLNILHNLQA-DVVGADVVEFNPQRDTVDGMTAMVAAKLV 333
>Hs4502215 [E] KOG2965 Arginase
Length = 354
Score = 53.1 bits (126), Expect = 8e-07
Identities = 74/329 (22%), Positives = 125/329 (37%), Gaps = 66/329 (20%)
Query: 139 IAIVGAPFDTSVSYRPGARFGPNGIRQGSRRLGNGISPVRGFPGSKLRKLDPYHSGYKIV 198
+A++GAPF R G GP IR+ +L L G +
Sbjct: 26 VAVIGAPFSQGQK-RKGVEHGPAAIREAGLM-------------KRLSSL-----GCHLK 66
Query: 199 DCGDIPMTPFDNKLALNQLYRGQRALHNHSSLVHKEQPPKL----------ITLGGDHTI 248
D GD+ TP N L R++ L ++E + +TLGGDH++
Sbjct: 67 DFGDLSFTPVPKDDLYNNLIVNPRSV----GLANQELAEVVSRAVSDGYSCVTLGGDHSL 122
Query: 249 TLMALRSAYEHYGKVSVIHFDSHLDTWDPKVLGGNISKRAGLNHG---TFL--------- 296
+ + H + V+ D+H D P ++ +G HG +FL
Sbjct: 123 AIGTISGHARHCPDLCVVWVDAHADINTP------LTTSSGNLHGQPVSFLLRELQDKVP 176
Query: 297 ---HFAHENGYLQDDKNIHVGIRAPYIAPGFYDEDHDYECGFEKIVARDLDIISLKEVVS 353
F+ + +++G+R F +++D + RD+D + +++V+
Sbjct: 177 QLPGFSWIKPCISSASIVYIGLRDVDPPEHFILKNYD----IQYFSMRDIDRLGIQKVME 232
Query: 354 -----AIKKRVGDGPVYISVDIDVVDLASAXXXXXXXXXXXXSRELLTILDGLEGLNIIG 408
I KR P+++S DID D A RE + I + + ++
Sbjct: 233 RTFDLLIGKR--QRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLS 290
Query: 409 A-DIVEVLPAFDTNGDITTIIAAQVVDSI 436
A D+VEV P T+ + A VD I
Sbjct: 291 ALDLVEVNPQLATSEEEAKTTANLAVDVI 319
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.139 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,742,536
Number of Sequences: 60738
Number of extensions: 1295769
Number of successful extensions: 2782
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2756
Number of HSP's gapped (non-prelim): 7
length of query: 447
length of database: 30,389,216
effective HSP length: 110
effective length of query: 337
effective length of database: 23,708,036
effective search space: 7989608132
effective search space used: 7989608132
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)