ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI1280 good R KOG1825 General function prediction only Fry-like conserved proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI1280 444673 451446 2258
(2258 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL129c [R] KOG1825 Fry-like conserved proteins 2514 0.0
SPBP19A11.04c [R] KOG1825 Fry-like conserved proteins 646 0.0
At5g15680 [R] KOG1825 Fry-like conserved proteins 146 3e-34
7294898 [R] KOG1825 Fry-like conserved proteins 113 4e-24
Hs12957488 [R] KOG1825 Fry-like conserved proteins 112 9e-24
CE25860 [R] KOG1825 Fry-like conserved proteins 100 3e-20
7294904 [R] KOG1825 Fry-like conserved proteins 79 6e-14
Hs22043621 [R] KOG1825 Fry-like conserved proteins 77 4e-13
Hs22043623 [R] KOG1825 Fry-like conserved proteins 69 9e-11
>YIL129c [R] KOG1825 Fry-like conserved proteins
Length = 2376
Score = 2514 bits (6516), Expect = 0.0
Identities = 1293/2299 (56%), Positives = 1653/2299 (71%), Gaps = 77/2299 (3%)
Query: 4 GFMFPPVGKENRAHGTLLSDDMGNDFKFPSXXXXXXXXXXXXXYPSTQIDQGAVQHSNTD 63
GF FPP N+A G+ ++ + D PS ++ + S TD
Sbjct: 16 GFTFPPT---NKAEGSSNNNQISIDID-PSGQDVLEEIN------EAPLNTFPLHQSVTD 65
Query: 64 YPQQTLNIIDIP-PVDPNGVTPEQFHINALQLNKPGDNLSNKIT----------NNINYS 112
P IIDIP P D + T + Q + G + N I+
Sbjct: 66 AP-----IIDIPSPTDMSEGTSLNNQLLLRQQQQQGTGEGQALPPTFVEEQSDQNKISML 120
Query: 113 INEVSQQPRPDPASANSTS-SFPDEYVAGLRQKSATDWKSPSEYALHILFTKFVRFAEMK 171
+ E QQ + A + T+ S ++YV LRQ+ ATDWKSPSEYALHILFTKF+R+AE K
Sbjct: 121 LPEQKQQRMQESAPPDITAKSVAEDYVTTLRQQMATDWKSPSEYALHILFTKFIRYAENK 180
Query: 172 LNICLQYPRETEPPIIEILGEGKDIEFDKIIESLGFISKKNAKPVIDAMMFWRKTKSEVA 231
LN+CLQ EPPI+EILGEG D FD+II+SLG I+KK KPVIDAMMFWRKTKSE A
Sbjct: 181 LNMCLQQLDMAEPPIVEILGEGVDPSFDEIIKSLGHIAKKKPKPVIDAMMFWRKTKSEAA 240
Query: 232 ALAAEKLDKIMQEYE--------------------------QYVKNNEQVXXXXXXXXXX 265
A+E+++K+++EYE +Y NN
Sbjct: 241 NSASEEMEKLLKEYEFEKAHPSQAHFLMNRRLSRSSSNTTSKYKHNNNTNNLPGMKRHVS 300
Query: 266 XXXXXXXXXXXXXXXXXXXXXXXXXXDPKFASLENQVERTKEMAFQADRKSLITIYILCR 325
+ + SLEN +E KE AF ADRKSLI+IYILCR
Sbjct: 301 SSFNNKVPLIKASSSNNSATSSPSIANSQLKSLENTIEVAKEEAFLADRKSLISIYILCR 360
Query: 326 VLIEIVKQNPMDFDDELSTKLEGIVFTQLKTTDPSSLSSTLIKSANWNSFAELLGWMSEK 385
VL EIVKQ + +++LS KLE IVFTQLKTTDP S+S++LIKS+NWNSFAELLG MSEK
Sbjct: 361 VLNEIVKQASSNEEEDLSDKLEEIVFTQLKTTDPLSISTSLIKSSNWNSFAELLGSMSEK 420
Query: 386 KFISVSDKFIADLEKIPPKVPRDQEPSVHLLILGMRYLRLKNYPLEMFEESAGFIKSISK 445
KF+SVSD+FIADLEKIP +P + EPS HLLILGMRYL+L+NYPLE FEESA F+KS+SK
Sbjct: 421 KFLSVSDRFIADLEKIPAYIPPELEPSTHLLILGMRYLKLRNYPLEKFEESADFMKSLSK 480
Query: 446 FFAPSQNTSIRLAYAEVLSQLLLPLAGAMTAEANHPTWIEAMTSILATCKKLQTDSKCWT 505
FFA ++N + LAYAEV +QLLLPLAG++TAE NHPTW+EAM+++L T K+LQ DSK W
Sbjct: 481 FFAKTENFPVCLAYAEVTNQLLLPLAGSLTAEVNHPTWVEAMSTLLNTAKRLQADSKYWV 540
Query: 506 LAFKLTVAVLCVSDTELFSKNWLSLIEKNVTKIKSKSLEDRVAFSMGLSRLIWVYLFRCX 565
FKLTV++LC S +LFSK WLSL+E N +K+KSKSL +R+ F++GLSRL+WVYL+RC
Sbjct: 541 SGFKLTVSILCASPPDLFSKQWLSLLEANASKVKSKSLNERIIFAVGLSRLVWVYLYRCP 600
Query: 566 XXXXXXXXXXXXXXXXXXXXXXXENWITTDMDIINPLCDVFVTVGYVHPTFVFENVLLHL 625
ENWIT D ++NPL D +++G++HP F+ E L+ L
Sbjct: 601 ETLNNTTRTLTKLLQLYLNTRKKENWITGDFGLLNPLTDALISIGFLHPNFLMEQALIPL 660
Query: 626 MKSSFNGTNLENIAHEKLILVINTYRGLLMTKERPIFPDGERRFYEVDLNKISVHS-SDK 684
++ SFNG+NLENI +EKLIL INTY+GLL+TKERP FP+ + R YE++LN I+V+ +
Sbjct: 661 IRQSFNGSNLENINYEKLILTINTYKGLLVTKERPRFPEDDNRLYELNLNNITVNQVQEA 720
Query: 685 NWANHEELVKYLYKLFMLLDSNIGSEVWSPENEHRRQPSTPFSNITNFGFGINNDNSANY 744
+ NH E+ Y YKLF+LLDS+IGSEVWSPEN+H++Q S FS FGF +NDN ++
Sbjct: 721 SSINHTEISDYFYKLFLLLDSSIGSEVWSPENQHQKQSSNAFSP---FGFSFSNDNDSSK 777
Query: 745 ARSLNMALFATLIEVLPCCLSVSQSIPFKSTIEILSRNAVHADQLIATSAQNALKVLAAK 804
+SL + LF T+IE +PCCLS+S++IP+KSTIEILSRNAVH++ +I++S+QNAL+ LA+K
Sbjct: 778 NKSLYVILFGTIIEAIPCCLSISRTIPYKSTIEILSRNAVHSEVIISSSSQNALRALASK 837
Query: 805 KNPYTLITWFAKYSFDFDEKTQSRYSLYYLSSAEYRTLLALYVELLECWLEDFTKNDIQQ 864
KNPYTLITWFAKYSFDFDEKTQS Y++ YLSS EY LL LYVELLECWLE+F ++ ++
Sbjct: 838 KNPYTLITWFAKYSFDFDEKTQSSYNMSYLSSKEYNRLLILYVELLECWLEEFQSSNKEE 897
Query: 865 SESDAALNGMKLPPKTLEANY-HELEKIEWKNTQTVVEDVEGNGLFFLCSADASIRRLAI 923
++ + L+G++L P E +E EK+EWKNT TV+E+VEGNGLFFLCS DA IRRL I
Sbjct: 898 NKKETGLDGIRLLPIDAEQEESNETEKLEWKNTVTVIEEVEGNGLFFLCSHDAKIRRLGI 957
Query: 924 QILQLTSKFDKALMQKATTYDKGHSRSSSRLVAESGSRLIDMLPSYDIPKLLEPEKQSLS 983
QIL++ KFD+A+M+K GHSRSSS A+ G+RLID+L + L+ P K +LS
Sbjct: 958 QILRIIFKFDEAMMEKTEKLSNGHSRSSSHFAADRGTRLIDLLNECNTTTLINPHKATLS 1017
Query: 984 VAEKSRLVKLTMKSKTNILVRLCESEYGVDAALWQRVFPKLLTYIFEQSPVTMALCRSIV 1043
EK+R +L K K +L++L ESEYGVDAALWQR FPKLL +F+ P+ MALCRSIV
Sbjct: 1018 AVEKTRFSRLNSKYKRGLLIKLAESEYGVDAALWQRAFPKLLALVFKTCPMAMALCRSIV 1077
Query: 1044 CIRLVQLYELILSIMSNSTEKFKDILPEAVVNQWKLYLIVACSSLTSTNDQKLHIPAATG 1103
CIRLVQ++E+IL + ++ K K++LPE +VNQWKLYLI AC+SLTST DQKLHIP+
Sbjct: 1078 CIRLVQVHEIILRVANDVDFKLKNVLPETIVNQWKLYLIAACTSLTSTFDQKLHIPSNIP 1137
Query: 1104 QHGRKKSQQIFTVQHQKIKSATSVFKMVLPLLNCNKNFIKSAVITGLSAMNINIYRAYIE 1163
QHGRKKSQQIFTVQHQKIKSA S+FKMVLPLLN I+ A+ITGLS+MNINI++AY+E
Sbjct: 1138 QHGRKKSQQIFTVQHQKIKSAKSIFKMVLPLLNAKYIMIRDAIITGLSSMNINIFKAYVE 1197
Query: 1164 SIDQFMTSWNINSSNNVMRMEMVHILVILSPFLQDPLINSDDWILQKLSHYLKEMKSFLE 1223
+ID F+ +W SSNN +R+EM HIL ILSP+L+ +I +D+WIL+KLS +L++ K FLE
Sbjct: 1198 AIDVFLVAWKEGSSNNQIRVEMFHILTILSPYLKSDMIFNDEWILRKLSEFLQKTKQFLE 1257
Query: 1224 IDEVQKSFEFQPLRHXXXXXXXXXXXXIRTKVDCDTFFPFEARASCFNFLKEWCGYGQYT 1283
D VQ S+E+Q LR +R D FPF+ARASCFNFLKEWCGYG+Y
Sbjct: 1258 KDSVQISYEYQSLRSYFAGLILSYYMAVREHPLIDELFPFQARASCFNFLKEWCGYGEYE 1317
Query: 1284 SLSSQRYRYMAANSQKAYEDATFATALEFQKSKLETVALECMIVLCSGEVSKTIYDTNGL 1343
+S +RY M N++ + T +EFQK++L+ + LE M+VLCS +++T+ D L
Sbjct: 1318 PISEERYAIMIKNTESGRDRTAITTGIEFQKNRLQMIVLETMVVLCSDPITQTLDDDLEL 1377
Query: 1344 PIQMSFDIAGLLCWIDSLLHAPNDKIKILGVRALKTILEANTSNVQLMRDVLHQIKLQTS 1403
PI +SFD LL WI++L + N +K LGVRAL+ +L+ N N +L RDV Q S
Sbjct: 1378 PIVISFDTEDLLAWIEALFDSDNTTVKNLGVRALENLLDKNRENFKLFRDVAFQCVSHHS 1437
Query: 1404 DNLIHHAYYSLFCEAICRQDTLLLTEDELVAFGLNGVVSNDKAMREHAIDLLIFIESKLY 1463
+ YY+ C+++ + D L+L EDELV+ GL G+V++ + R A+DLL +E+KL+
Sbjct: 1438 HPSVAVLYYTTLCKSVLKLDNLVLDEDELVSLGLYGLVADKEDTRTFAVDLLSAVETKLH 1497
Query: 1464 ESSYARIFKERLSNQSKTVYKSTAQEISNIFAELLPQEVRLKVFSRMSEYFHLLPTELKQ 1523
SSY ++FKERL+N SKTVYKSTA+EIS+IFAELL Q++ L++FS + L P E+K+
Sbjct: 1498 NSSYTKVFKERLANSSKTVYKSTAKEISSIFAELLSQDLCLRIFSSLVRILDLFPFEIKR 1557
Query: 1524 NVLVMFVPWVNKFTLKSSEDLDTFMVLNNTFALTIYSKNRYPMEVEQLWISLGKGNSFQN 1583
++LV+ VPWVNKFTLKS E+LDTFMVLNN F +TI + P EVEQLWISLGKGNSFQN
Sbjct: 1558 DLLVLMVPWVNKFTLKSLEELDTFMVLNNLFYITIDLNDSLPNEVEQLWISLGKGNSFQN 1617
Query: 1584 IHVVLEYIISTSINCRNPEFVKHAREIVLFLANVPGGMGVIDTLFHSLEPKHIIPTSKIL 1643
IHV LEYII++S+N NP FV++AR+IVL+LAN+PGG+G++DTL ++LEPK+++P +K
Sbjct: 1618 IHVSLEYIINSSMNHCNPLFVQYARDIVLYLANIPGGIGLLDTLLNNLEPKYMVPLAKHT 1677
Query: 1644 REEPQNNDKYSFIADIWTILDYRGKDVVFSKAQLSMIFLVNLLIIPNESVKSRLPLLLHI 1703
EP NN+KYSF+ +IW L+Y GK ++FSKAQLS+IFLVNLL +ESVK+++PLLLH+
Sbjct: 1678 FNEPMNNNKYSFLGNIWERLNYNGKRIIFSKAQLSIIFLVNLLTNLSESVKAKIPLLLHM 1737
Query: 1704 SVCLLDHHVPIIQDSASRILCGIIYGLEPTNKNSDETVNLIKNRQMLWTYENLTKESGAR 1763
S+CLLDH+VP+I +SA +I +I+GL P+++ S+ETV L++N+ LW+Y+NL K+ GAR
Sbjct: 1738 SICLLDHYVPLIHESACKIASTLIFGLAPSHEKSEETVKLLRNKHALWSYDNLMKK-GAR 1796
Query: 1764 SPKSMDTMIRNIISIFSEIETLQEDWQRISLKWATTCSVRHIACRSFQIFRSLLTFLDQE 1823
SPK+MD +IRNIISIFS+++ Q WQRI+LKWATTCSVRHIACRSFQIFRSLLTFLDQE
Sbjct: 1797 SPKTMDLLIRNIISIFSDLDEFQVTWQRIALKWATTCSVRHIACRSFQIFRSLLTFLDQE 1856
Query: 1824 MLRDMLHRLSNTISDENPDIQGFAMQILMTLNAITAELNADKLIDFPQLFWSVVACLNTI 1883
MLRDMLHRLSNTISD N DIQGFAMQILMTLNAI AEL+ LI FPQLFWS+ ACL++I
Sbjct: 1857 MLRDMLHRLSNTISDGNVDIQGFAMQILMTLNAIMAELDPTNLISFPQLFWSITACLSSI 1916
Query: 1884 HEQEFIEVLSSLSKFVSKIDLDSPDTVQCLISTFPSNWEGKFDGLQQIVMIGLRSCNSWE 1943
HEQEFIEVLS LSKF+SKIDLDSPDTVQCL++ FPSNWEG+FDGLQQIVM GLRS NS E
Sbjct: 1917 HEQEFIEVLSCLSKFISKIDLDSPDTVQCLVAIFPSNWEGRFDGLQQIVMTGLRSANSLE 1976
Query: 1944 ISLQFLDRLNLLNDSQIIANKESRILYALLANLPRFLYALDTNDMNDGVVRGANCLISLC 2003
I+ +FLD+LNLL DS+IIAN ESR+L+AL+ANLPRFL A+D D G+ A+ LI L
Sbjct: 1977 ITWKFLDKLNLLKDSRIIANTESRLLFALIANLPRFLNAMDRKDFT-GIQVAADSLIELA 2035
Query: 2004 MANDEPSLSRIIDSMVKNKFRSKKDFMSQIVNFISSNFFPNYAPQALVFLLGLLFNSMDW 2063
A +PSLSR+IDS+ KNKFRSKKDFMSQ+V+FIS N+FP+Y+ Q LVFLLGLLFN + W
Sbjct: 2036 NAYKQPSLSRLIDSLAKNKFRSKKDFMSQVVSFISRNYFPSYSAQTLVFLLGLLFNKIGW 2095
Query: 2064 VKIQTMQLLKHIFPLTELSRPEFIGVGADFISPXXXXXXXXXXXXXXXVLNTIPKVSGSK 2123
+++QT+++LK++FPL +L RPEFIGVGAD ISP VL+ +P VSGSK
Sbjct: 2096 IRVQTLEILKYVFPLIDLRRPEFIGVGADLISPLLRLLFTEYEAKALEVLDCVPNVSGSK 2155
Query: 2124 MDKDVLRISMGNKDAKKVYNKTATLFGIPEESGWSIPMPALTAASTRHNVHAVFTTCAVM 2183
MDKDVLRI+MGNKD K N T TLFG+PE+SGWS+PMP +TAA+TRHNVHAVF TC
Sbjct: 2156 MDKDVLRITMGNKDVKDGDNATTTLFGLPEDSGWSVPMPTMTAATTRHNVHAVFMTCGTG 2215
Query: 2184 VGGEVD---------------NGD--SGILEEIVEFHADGGYVQGTDEFGDVVSVTEDKD 2226
EV +GD G ++ IVEFHADG Y G + D +SV E+KD
Sbjct: 2216 KSDEVSAHGSDDMDAVIEFHADGDYELGRMDTIVEFHADGDYDLGRMDTNDSISVAEEKD 2275
Query: 2227 PSLSHMWAELDDLGSFFNK 2245
SLSHMWAELD+L SFF K
Sbjct: 2276 ASLSHMWAELDNLDSFFTK 2294
>SPBP19A11.04c [R] KOG1825 Fry-like conserved proteins
Length = 2196
Score = 646 bits (1667), Expect = 0.0
Identities = 526/2017 (26%), Positives = 927/2017 (45%), Gaps = 186/2017 (9%)
Query: 313 DRKSLITIYILCRVLIEIVKQNPMDFDDELSTK-LEGIVFTQLKTTDPSSLSSTLIKSAN 371
+R+S I+IYILCRVL EI + P + +E + L VF QL + +SS+ AN
Sbjct: 128 ERRSSISIYILCRVLTEIAETIPSNALEESTVSCLLECVFHQLLSAKNLPVSSSYFSLAN 187
Query: 372 WNSFAELLGWMSEKKFISVSDKFIADLEKIPPKV--PRDQEPSVHLLILGMRYLRLKNYP 429
W SFA L+G MS F+ VSD+FI ++E + R +E + L+ MRYLRL+ YP
Sbjct: 188 WESFAFLVGSMSRFNFVMVSDRFIEEIEHLEKSGCDSRQKETVLVHLLRAMRYLRLQLYP 247
Query: 430 LEMFEESAGFIKSISKFFAPSQNTSIRLAYAEVLSQLLLPLAGAMTAEANHPTWIEAMTS 489
+ EES F++S++ FF + NT++++ YA ++ QLL PL T E N P W + +
Sbjct: 248 TTLLEESIAFLQSLTSFFMKA-NTALKIEYAYLMEQLLRPLISRATFEVNIPAWSRTIET 306
Query: 490 ILATCKKLQTDSKCWTLAFKLTVAVLCVSDTELFSKNWLSLIEKNVTKIKSKSLEDRVAF 549
I K+ T +K W + F +LC+S + F K+W+S ++ ++K + L R
Sbjct: 307 IYPVVLKMCTKTKYWNVFFPFCCTLLCLSPKQFFLKHWISSLDAAFFRVKDRRL--RNTG 364
Query: 550 SMGLSRLIWVYLFRCXXXXXXXXXXXXXXXXXXXXXXXXENWIT-TDMDIINPLCDVFVT 608
LSR++W Y + + + ++ ++ +
Sbjct: 365 LPHLSRVVWTYSNQYKEEPSIMNSNISNILKSGFSIGKKFSVVPFATLEELDGYAQIVRV 424
Query: 609 VGYVHPTFVFENVLLHLMKSSFNGTNLENIAHEKLILVINTYRGLL-----MTKERPIFP 663
VG P V + +L L +F ENI EKL++V+ + +L + IF
Sbjct: 425 VGAHFPELVIKEILTPLSTDAFT----ENIGPEKLMIVVRSVYYILHDMKYKKSDSTIFE 480
Query: 664 DGERRFYEVDLNKISVHSSDKNWANHEELVKYLYKLFMLLDSNIGSEVWSPENEHRRQPS 723
E F VDL++++V + + + H K L+ +F L
Sbjct: 481 YIEFEF--VDLHEVAVGTPLQQFV-HNLSQKLLFLVFQLS-------------------- 517
Query: 724 TPFSNITNFGFGINNDNSANYARSLNMALFATLIEVLPCCLSVSQSIPFKSTIEILSRNA 783
TN +++ N+ + +AL+ ++V PC + + + ++ L+ +
Sbjct: 518 ------TNTNCYLDSKNATSL-----LALYINALKVFPCLMGKLEQRVIDAYVKCLNCS- 565
Query: 784 VHADQLIATSAQNALKVLAAKKNPYTLITWFAKYSFDFDEKTQSRYSLYYLSSAEYRTLL 843
+++I T N+L ++ + S S + +EY LL
Sbjct: 566 ---NKIIHTVCHNSLIYFSS--------------GLKMSKSVISCLSRKLVKGSEY--LL 606
Query: 844 ALYVELLECWLEDFT-----KNDIQQSESDAALNGMKLPPKTLEANYHELEKIEWKNTQT 898
Y E++ W+ +N + ++S A+ P +++ +Y +++ W T
Sbjct: 607 RTYHEVIRIWISQQEAVIEKRNSVLSNKSCASSESNT--PASVKQDYDDIQS--W----T 658
Query: 899 VVEDVEGNGLFFLCSADASIRRLAIQILQLTSKFD-KALMQKATTYDKGHSRSSSRLVAE 957
++E+++ G+ L S IR+ A+ +L + + + LM + + G S +V
Sbjct: 659 IIEEIQSLGVLHLSSPSVGIRKFAVALLNDVKQLNTEYLMLSSDKVEVGDIYSEPTIV-- 716
Query: 958 SGSRLIDMLPSYDIPKLLEPEKQSLSVAEKSRLVKLTMKSKTNILVRLCESEYGVDAALW 1017
D+L D +L E + AE+SRL K ++L++L S GVD ++W
Sbjct: 717 ------DVLKDCD-SSILSVESHLPTAAERSRLRKFINDGTKDMLLKLATSNSGVDISIW 769
Query: 1018 QRVFPKLLTYIFEQSPVTMALCRSIVCIRLVQLYELILSIMSNSTEKFK-------DILP 1070
VFP+ + FE+ P TMAL R+ VC +L + +LS + +S F D P
Sbjct: 770 YNVFPRFIKVCFERFPTTMALLRNTVCEKLPSITMQLLSRIESSELNFNLKSAVKNDNFP 829
Query: 1071 EAVVNQWKLYLIVACSSLTSTND--------QKLHIPAATGQHGRKKSQQIFTVQHQKIK 1122
E ++ QWKLYLIVAC ++T T++ ++ +G H R + I KI
Sbjct: 830 EFLLVQWKLYLIVACCTITYTSNVDYSHTDLRRTLTAVQSGNHLRGLQETI------KIT 883
Query: 1123 SATSVFKMVLPLLNCNKNFIKSAVITGLSAMNINIY-------RAYIESIDQ-------- 1167
SA S+F MVLPL+ + I+ AV+ + +N+N + + YI + Q
Sbjct: 884 SAESLFSMVLPLIFTEFSPIREAVVFAIGCINVNAFPQLVRSLKPYISVLKQDHQEFIFA 943
Query: 1168 ---FMTSWNINSSNNVMRMEMVHILVILSPFLQDPLINSDDWILQKLSHYLKEMKSFLEI 1224
F + N + ++R E+ HI + S L L+N D L +S +LK++K FL
Sbjct: 944 GLNFPSVKRRNKPDLLLRSEIAHIFAMTSHLLLHELLNEDREALSVISEFLKDLKGFLST 1003
Query: 1225 DEVQKSFEFQPLRHXXXXXXXXXXXXIRTKVDCDTFFPFEARASCFNFLKEWCGYGQYTS 1284
VQ ++ LR ++ PF RASC+ L EW G+G +
Sbjct: 1004 PNVQADEKYLKLR-CYFSQLLEKVLLVQNLHPSSEVLPFSGRASCWKLLDEWTGFGPARA 1062
Query: 1285 LSSQRYRYMAA----NSQKAYEDATFATALEFQKSKLETVALECMIVLCSGEVSKTIYDT 1340
++ R M A N++ E + E K LE +A++ MI LC+ ++ + + T
Sbjct: 1063 ITKNREELMRAHIRGNNKDIRERDKLLASFEAGKQNLEYLAIKAMIALCTAKLQQEL--T 1120
Query: 1341 NGLPIQMSFDIAGLLCWIDSLLHAPNDKIKILGVRALKTILEANTSNVQLMRDVLHQIKL 1400
G+ + FDI LL W ++ +P+ I L + L +L N+SN L++ V+++
Sbjct: 1121 EGVFL---FDIEILLNWFTAVFGSPSKAIVGLARKGLTALLLENSSNEVLLQKVINRCFS 1177
Query: 1401 QTSDNLIHHAYYSLFCEAICRQDTLLLTEDELVAFGLNGVVSNDKAMREHAIDLLIFIES 1460
+ I + Y+ E + + + L++ +L+ L + +N+ ++R A +LL
Sbjct: 1178 KEISQTISNYYFLSLSEMLIQINPNNLSKPKLLPLCLVNLSTNNLSVRLKAFELLGNFHL 1237
Query: 1461 KLYESSYARIFKERLSNQSKTVYKSTAQEISNIFAELLPQEVRLKVFSRMSE---YFHLL 1517
+ + FK L + + +Y +F+ L + F+ SE YF+
Sbjct: 1238 NNFTMTALMEFKTFLESSNPALYLKPQY----LFSVQLASDFTEDSFTLTSECLRYFNY- 1292
Query: 1518 PTELKQNVLVMFVPWVNKFTLKSSEDLDTF-----MVLNNTFALTIYSKNRYPMEVEQLW 1572
+ ++ ++ + +PW+ LK + TF ++L + +T N P E+E LW
Sbjct: 1293 GHQHRRGLVTVLLPWLQNLELKMDVENKTFDSFTAVILIDLIEVTAKFTNDLPNEIEALW 1352
Query: 1573 ISLGKGNSFQNIHVVLEYIISTSINCRNPEFVKHAREIVLFLANVPGGMGVIDTLFHSLE 1632
SL N V+L +++ + FV R+I ++LA + TL +
Sbjct: 1353 TSLALSRHKSNWTVILFFLMQQCYQRKTFSFVDCTRQITIYLAKTELLSDLYSTLLSFVC 1412
Query: 1633 PKHIIPTSKILREEPQNNDKYSFIADIWTILDYRGKDVVFSKAQLSMIFLVNLLIIPNES 1692
P ++ ++ + + + +++A++ + + +S QLS++ L+++L PN S
Sbjct: 1413 PANVSNENQEVYKFSLEDLSSTYVANLEDLFPSEKNHISYSPCQLSLLLLMDIL--PNPS 1470
Query: 1693 ---VKSRLPLLLHISVCLLDHHVPIIQDSASRILCGII---YGLEPTNKNSDETVNLIKN 1746
V + +LH + DH+ I+Q+ +I ++ +E D +
Sbjct: 1471 IITVTDDVATILHAAFIQFDHYSRIVQEQCQQIFQYVVRKVLAMEGRLDYDDAYFDFNVE 1530
Query: 1747 RQMLWTYENLTKESGARSPKSMDTMIRNIISIFSEIETLQEDWQRISLKWATTCSVRHIA 1806
++ TK+ K + +++ I + S L++ W ++L WATTC R +A
Sbjct: 1531 SSLITGLRGKTKKEDDLV-KYHNMILKTIELLSSSYPELKQIWGEVALSWATTCPSRRLA 1589
Query: 1807 CRSFQIFRSLLTFLDQEMLRDMLHRLSNTISDENPDIQGFAMQILMTLNAITAELNADKL 1866
C SFQ+FRSLL D ML +++ RL TISDE ++ ++++IL T N+ +N+D L
Sbjct: 1590 CNSFQLFRSLLPDFDARMLLEIISRLVGTISDETSYLRDYSVEILRTFNSYVLVMNSDDL 1649
Query: 1867 IDFPQLFWSVVACLNTIHEQEFIEVLSSLSKFVSKIDLDSPDTVQCLISTFPSNWEGKFD 1926
+ + Q+ W+ +ACL TIHE EFIE + + +++ ++ Q ++ TFP NW G +
Sbjct: 1650 LSYSQILWTAIACLTTIHEDEFIESVKIAYAYFLRVE-ETDSATQQIMETFPQNWVGDYQ 1708
Query: 1927 GLQQIVMIGLRSCNSWEISLQFLDRLNLLNDSQIIANKESRILYALLANLPRFLYALDTN 1986
GLQ +++ G RS NS+EI++ F L D+ ++ RIL LL +LP +Y + +
Sbjct: 1709 GLQILILKGFRSTNSFEITMNFFLLLMDFKDNDLVGVGYLRILSCLLVSLPAMVYTYEHS 1768
Query: 1987 D-MNDGVVRGANCLISLCMANDEPSLSRIIDSMVKNKFRSKKDFMSQIVNFISSNFFPNY 2045
D + + + L +L ++ +L ++D+ +K KFRS KDF+ V+++ S +F +Y
Sbjct: 1769 DPITFDLSVFCHKLATLASQFNDDALIELLDTYLKRKFRSIKDFLKHTVSYLYSYYFEDY 1828
Query: 2046 APQALVFLLGLLFNSMDWVKIQTMQLLKHIFPLTELSRPEFIGVGADFISPXXXXXXXXX 2105
+ + L L N++ W + T+ +LK +FPL + +P + G +SP
Sbjct: 1829 ELEIVSTLTMFLSNNLTWFRKSTLDVLKELFPLIDFQKPIYSEHGLGIVSPLLRLLPTGY 1888
Query: 2106 XXXXXXVLNTIPKVSGSKMDKDVLRISMGNKDAKKVYNKTATLFGIPEESGWSIPMPALT 2165
+L + D L++ M + K ++ A F IP+E GW P
Sbjct: 1889 AMEALSLLTDSVLHVSAPTDMQTLKLLMVDPKLKNSDDRLAGFFEIPDEDGWYEPNSEYA 1948
Query: 2166 AASTRHNVHAVFTTCAVMVGGEVDNGDSGILEEIVEFHAD--GGYVQ--GTDEFGDVVSV 2221
AA T+ NVHAVF +C+ ++ + V FHAD Y + TD G +
Sbjct: 1949 AAITKSNVHAVFYSCSTT--------EASVSTPEVRFHADEVSNYPRHVPTDSHGSL--- 1997
Query: 2222 TEDKDPSLSHMWAELDDLGSFFNKSDFMEEEQEEDDV 2258
+ SL + L L FF ++ +EE + DV
Sbjct: 1998 ---DENSLGELVTTLHSLDVFF--AEDRDEELIQPDV 2029
Score = 56.2 bits (134), Expect = 6e-07
Identities = 30/91 (32%), Positives = 53/91 (57%), Gaps = 12/91 (13%)
Query: 154 EYALHILFTKFVRFAEMKLNICLQYP----RETEP--------PIIEILGEGKDIEFDKI 201
+YALHILFT+FVR +E K++ +Y + EP I +L +G+D EFD+
Sbjct: 28 DYALHILFTQFVRLSEQKISFLSRYHANEGKNAEPVRFNVGEQEAILLLKKGEDNEFDRC 87
Query: 202 IESLGFISKKNAKPVIDAMMFWRKTKSEVAA 232
I++L ++ VI++++ WRK + ++ +
Sbjct: 88 IQALVALASSKPVAVIESLLCWRKVRVDITS 118
>At5g15680 [R] KOG1825 Fry-like conserved proteins
Length = 2163
Score = 146 bits (369), Expect = 3e-34
Identities = 104/435 (23%), Positives = 192/435 (43%), Gaps = 52/435 (11%)
Query: 1675 AQLSMIFLVNLLIIPNESVKSRLPLLLHISVCLLDHHVPIIQDSASRILCGIIYGL---- 1730
A +++I L + +E + LPLL H++ +D I+ + +L ++Y L
Sbjct: 1565 ADIALILLAEIAYENDEDFREHLPLLFHVTFVSMDSSEDIVLEHCQHLLVNLLYSLAGRH 1624
Query: 1731 -------EPTNKNSDETVNLIKNRQ-----MLWTYENLTK-ESGARSPKSMDTMIRNIIS 1777
+N + V+LIK Q M+W E+ T + S + ++++++
Sbjct: 1625 LELYEVENSDGENKQQVVSLIKYVQSKRGSMMWENEDPTVVRTDLPSAALLSALVQSMVD 1684
Query: 1778 IFSEIETLQEDWQRISLKWATTCSVRHIACRSFQIFRSLLTFLDQEMLRDMLHRLSNTIS 1837
L+E W +LKWA C+ RH+ACRS QI+R+L + + +L L +S
Sbjct: 1685 AIFFQGDLRETWGTEALKWAMECTSRHLACRSHQIYRALRPSVTSDACVSLLRCLHRCLS 1744
Query: 1838 DENPDIQGFAMQILMTLNAITAELNADKLIDFPQLFWSVVACLNTIHEQEFIEVLSSLSK 1897
+ P + GF M+IL+TL + + +K+I +PQLFW VA ++T + +VL S+
Sbjct: 1745 NPIPPVLGFIMEILLTLQVMVENMEPEKVILYPQLFWGCVAMMHTDFVHVYCQVLELFSR 1804
Query: 1898 FVSKIDLDSPDTVQCLISTFP-------------------------SNWEGKFDGLQQIV 1932
+ ++ T L+S+ P S KF+G+Q +V
Sbjct: 1805 IIDRLSFRDKTTENVLLSSMPRDEFNTNDLGEFQRSESRGYEMPPSSGTLPKFEGVQPLV 1864
Query: 1933 MIGLRSCNSWEISLQFLDRLNLLNDSQIIANKESRILYALLANLP----------RFLYA 1982
+ GL S S E S++ L R+ + + I + E+R+L + LP + A
Sbjct: 1865 LKGLMSTVSHEFSIEVLSRITVPSCDSIFGDAETRLLMHITGLLPWLCLQLTQDQVMVSA 1924
Query: 1983 LDTNDMNDGVVRGANCLISLCMANDEPSLSRIIDSMVKNKFRSKKDFMSQIVNFISSNFF 2042
L A+ + C A L+ + + + + + ++ ++ + + + +F
Sbjct: 1925 LPLQQQYQKACSVASNIAVWCRAKSLDELATVFVAYARGEIKRVENLLACVSPLLCNKWF 1984
Query: 2043 PNYAPQALVFLLGLL 2057
P ++ A LL LL
Sbjct: 1985 PKHSALAFGHLLRLL 1999
>7294898 [R] KOG1825 Fry-like conserved proteins
Length = 1632
Score = 113 bits (282), Expect = 4e-24
Identities = 77/267 (28%), Positives = 135/267 (49%), Gaps = 13/267 (4%)
Query: 305 TKEMAFQADRKSLITIYILCRVLIEIVKQNPMD-FDDELSTKLEGIVFTQLKTTD----- 358
T ++ FQ R+ +I C LIEI+KQ P ++L +E + F K D
Sbjct: 385 TVDLDFQLQRREAAVEFIFCLALIEILKQLPYHPGHEDLVRSIENLAFKHFKYKDGLQNN 444
Query: 359 PSSLSSTLIKSANWNSFAELLGWMSEKKFISVSDKFIADLEKIPPK-VPRDQEPSVHLLI 417
P++L+ +I +AE++G +++ +F SV +F+++L+++ K V S+ L+
Sbjct: 445 PNALNIHMIADL----YAEVIGVLAQSRFASVRKRFMSELKELRGKEVSPTTTQSIISLL 500
Query: 418 LGMRYLRLKNYPLEMFEESAGFIKSISKFFAPSQNTSIRLAYAEVLSQLLLPLAGAMTAE 477
+GM++ R+K P+E FE S F+ ++F ++ I+ A A + ++L+P+A A+ E
Sbjct: 501 MGMKFFRVKMVPIEEFEASFQFMHECGQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNE 560
Query: 478 ANHPTWIEAMTSILATCKKLQTDSKCWTLAFKLTVAVLCVSDTELFSKNWLSLIEKNVTK 537
N P + + T SK F L +LCVS F NW + ++
Sbjct: 561 VNVPCVKNFVELLYVQTLDASTKSKHRLALFPLVTCLLCVSQKTFFLTNWHYFLAMCLSN 620
Query: 538 IKSKSLE-DRVAFSMGLSRLIWVYLFR 563
+K++ + RVA L RL+WVY+ R
Sbjct: 621 LKNRDAKMSRVALE-SLFRLLWVYMIR 646
>Hs12957488 [R] KOG1825 Fry-like conserved proteins
Length = 3012
Score = 112 bits (279), Expect = 9e-24
Identities = 100/417 (23%), Positives = 180/417 (42%), Gaps = 66/417 (15%)
Query: 152 PSEYALHILFTKFVRFAEMKLNICLQYPRETEPPIIEILGEGKDIEFDKIIESLGFISKK 211
P EY L LF F AE K+ I + P E P+ + L G+D
Sbjct: 62 PGEYVLKSLFVNFTTQAERKIRIIMAEP--LEKPLTKSLQRGED---------------- 103
Query: 212 NAKPVIDAMMFWRKTKSEVAALAAEKLDKIMQEYEQYVKNNEQVXXXXXXXXXXXXXXXX 271
P D ++ S +++L+ L I++ + K +
Sbjct: 104 ---PQFDQVI------SSMSSLSEYCLPSILRTLFDWYKRQNGIEDESHEYR-------- 146
Query: 272 XXXXXXXXXXXXXXXXXXXXDPKFASLENQVERTKEMAFQADRKSLITIYILCRVLIEIV 331
P+ ++ E+ ++ + +R+ L +I VLIE++
Sbjct: 147 ---------------------PRTSNKSKSDEQQRD--YLMERRDLAIDFIFSLVLIEVL 183
Query: 332 KQNPMD-FDDELSTKLEGIVFTQLKTTDPSSLSSTLIKSANWNSFAELLGWMSEKKFISV 390
KQ P+ D L + + F K + +T + +AE++G +++ KF +V
Sbjct: 184 KQIPLHPVIDSLIHDVINLAFKHFKYKEGYLGPNTGNMHIVADLYAEVIGVLAQAKFPAV 243
Query: 391 SDKFIADLEKIPPKVPRDQEP----SVHLLILGMRYLRLKNYPLEMFEESAGFIKSISKF 446
KF+A+L+++ K +Q P S+ LI+GM++ R+K YP+E FE S F++ + +
Sbjct: 244 KKKFMAELKELRHK---EQNPYVVQSIISLIMGMKFFRIKMYPVEDFEASLQFMQECAHY 300
Query: 447 FAPSQNTSIRLAYAEVLSQLLLPLAGAMTAEANHPTWIEAMTSILATCKKLQTDSKCWTL 506
F ++ I+ A A + ++L+P+A A+ E N P + S+ T +L + K
Sbjct: 301 FLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLELSSRKKHSLA 360
Query: 507 AFKLTVAVLCVSDTELFSKNWLSLIEKNVTKIKSKSLEDRVAFSMGLSRLIWVYLFR 563
+ L +LCVS +LF W + ++ +K+K + L RL+WVY+ R
Sbjct: 361 LYPLVTCLLCVSQKQLFLNRWHIFLNNCLSNLKNKDPKMARVALESLYRLLWVYMIR 417
Score = 75.9 bits (185), Expect = 7e-13
Identities = 42/136 (30%), Positives = 76/136 (55%), Gaps = 6/136 (4%)
Query: 1733 TNKNSDETVNLIKNRQM--LWTYENLT-KESGARSPKSMDTMIRNIISIFSEIET---LQ 1786
T++ +++ + + R LW +E++T K ++S + + +R+++S+F + ++ L+
Sbjct: 1787 TDEKANKLIEFLTTRAFGPLWCHEDITPKNQNSKSAEQLTNFLRHVVSVFKDSKSGFHLE 1846
Query: 1787 EDWQRISLKWATTCSVRHIACRSFQIFRSLLTFLDQEMLRDMLHRLSNTISDENPDIQGF 1846
++L+ A S RH A RSFQIFR+L L L D+L RL I + +IQG+
Sbjct: 1847 HQLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHGDEIQGY 1906
Query: 1847 AMQILMTLNAITAELN 1862
M+ L+TL A L+
Sbjct: 1907 VMEALLTLEAAVDNLS 1922
>CE25860 [R] KOG1825 Fry-like conserved proteins
Length = 2858
Score = 100 bits (249), Expect = 3e-20
Identities = 66/265 (24%), Positives = 121/265 (44%), Gaps = 9/265 (3%)
Query: 305 TKEMAFQADRKSLITIYILCRVLIEIVKQNPMDFD--DELSTKLEGIVFTQLKTTDPSSL 362
T E+ + +K L Y+ C VLIEI+ Q D L K+ I F ++ +PS++
Sbjct: 90 TPELRLKLHKKLLAVNYLFCLVLIEILPQVEFHLPQCDPLIKKVLEICFKNVQYREPSAV 149
Query: 363 SSTLIKSANW----NSFAELLGWMSEKKFISVSDKFIADLEKIPPKVPRDQEPSVHLLIL 418
I N ++ E++G +S F + F+ + ++ V + + LI+
Sbjct: 150 G---INKTNHLVVAETYGEVVGVLSSTYFTHIHRIFMTHITELKKDVSQTAAQQIVALIM 206
Query: 419 GMRYLRLKNYPLEMFEESAGFIKSISKFFAPSQNTSIRLAYAEVLSQLLLPLAGAMTAEA 478
M++LR+ + +E FE F+ + ++ ++ A +L ++LLP+A + E
Sbjct: 207 SMKFLRINSSQVEDFENGLKFLDDLGSLLLEVKDKDVKHAVMGLLVEILLPVAAQIKRET 266
Query: 479 NHPTWIEAMTSILATCKKLQTDSKCWTLAFKLTVAVLCVSDTELFSKNWLSLIEKNVTKI 538
N P I + + T + + + AF L +LCVS F NW+ + ++ +
Sbjct: 267 NIPALISLVQKLYTTTNDMISKKQHKLAAFPLITCLLCVSQKHFFLANWVQFLNSCLSHL 326
Query: 539 KSKSLEDRVAFSMGLSRLIWVYLFR 563
K+K + L RL+WVY+ R
Sbjct: 327 KNKDPQVARVALESLYRLLWVYMIR 351
>7294904 [R] KOG1825 Fry-like conserved proteins
Length = 1452
Score = 79.3 bits (194), Expect = 6e-14
Identities = 55/184 (29%), Positives = 95/184 (50%), Gaps = 19/184 (10%)
Query: 1685 LLIIPNESVKSRLPLLLHISVCLLDHHVPIIQDSASRILCGIIYGLEPTNKNSDETVNLI 1744
L I PN S S +PL+ D H P Q S + +I L + +T
Sbjct: 160 LQINPNNSENSEVPLIHP------DEHAPP-QPGPSMPIAHVIKSL--LKFLAQDTC--- 207
Query: 1745 KNRQMLWTYENLTKESGA-RSPKSMDTMIRNIISIFSEI---ETLQEDWQRISLKWATTC 1800
Q LW YE++T + A +S + + +++++ +F++ + E W + +L+ +C
Sbjct: 208 ---QPLWNYEDITAKVWAVKSAEQLSCFLKHMVKVFADSYPQARIAERWAQTALQLGLSC 264
Query: 1801 SVRHIACRSFQIFRSLLTFLDQEMLRDMLHRLSNTISDENPDIQGFAMQILMTLNAITAE 1860
S RH A R QIFR+L ++ ML D+L RL T++++ D+QG+ ++L+TL A
Sbjct: 265 SSRHYAGRCLQIFRALNVPINSRMLSDILSRLVETVAEQGEDMQGYVTELLLTLEAAVDS 324
Query: 1861 LNAD 1864
L++D
Sbjct: 325 LDSD 328
>Hs22043621 [R] KOG1825 Fry-like conserved proteins
Length = 1308
Score = 76.6 bits (187), Expect = 4e-13
Identities = 40/117 (34%), Positives = 69/117 (58%), Gaps = 5/117 (4%)
Query: 1745 KNRQMLWTYENLT-KESGARSPKSMDTMIRNIISIFSEIET----LQEDWQRISLKWATT 1799
+ R LW +E+++ K +S + + T +++++S+F + + L+ ++L+ A +
Sbjct: 55 RKRGPLWNHEDVSAKNPSIKSAEQLTTFLKHVVSVFKQSSSEGIHLEHHLSEVALQTALS 114
Query: 1800 CSVRHIACRSFQIFRSLLTFLDQEMLRDMLHRLSNTISDENPDIQGFAMQILMTLNA 1856
CS RH A RSFQIFR+L L L D+L RL T+ D D QGF +++L+TL +
Sbjct: 115 CSSRHYAGRSFQIFRALKQPLTATTLSDVLSRLVETVGDPGEDAQGFVIELLLTLES 171
>Hs22043623 [R] KOG1825 Fry-like conserved proteins
Length = 152
Score = 68.9 bits (167), Expect = 9e-11
Identities = 41/137 (29%), Positives = 72/137 (51%), Gaps = 2/137 (1%)
Query: 428 YPLEMFEESAGFIKSISKFFAPSQNTSIRLAYAEVLSQLLLPLAGAMTAEANHPTWIEAM 487
YP+E FE S F++ +++F ++ I+ A A + ++L+P+A A+ E N P +
Sbjct: 2 YPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFV 61
Query: 488 TSILATCKKLQTDSKCWTLAFKLTVAVLCVSDTELFSKNWLSLIEKNVTKIKSKSLE-DR 546
+ T +L + K + L +LCVS + F NW ++ ++ +K+K + R
Sbjct: 62 EMLYQTTFELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLKNKDPKMSR 121
Query: 547 VAFSMGLSRLIWVYLFR 563
VA L RL+WVY+ R
Sbjct: 122 VALE-SLYRLLWVYVIR 137
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 125,830,807
Number of Sequences: 60738
Number of extensions: 5262990
Number of successful extensions: 13801
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 13720
Number of HSP's gapped (non-prelim): 44
length of query: 2258
length of database: 30,389,216
effective HSP length: 122
effective length of query: 2136
effective length of database: 22,979,180
effective search space: 49083528480
effective search space used: 49083528480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)