ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI1316 good C KOG0557 Energy production and conversion Dihydrolipoamide acetyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI1316 464528 463110 -473
(473 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL071w [C] KOG0557 Dihydrolipoamide acetyltransferase 566 e-161
SPCC794.07 [C] KOG0557 Dihydrolipoamide acetyltransferase 374 e-103
CE09597 [C] KOG0557 Dihydrolipoamide acetyltransferase 317 3e-86
7297250 [C] KOG0557 Dihydrolipoamide acetyltransferase 301 1e-81
At3g52200 [C] KOG0557 Dihydrolipoamide acetyltransferase 293 5e-79
At3g13930 [C] KOG0557 Dihydrolipoamide acetyltransferase 292 6e-79
At1g54220 [C] KOG0557 Dihydrolipoamide acetyltransferase 279 6e-75
Hs17458911 [C] KOG0557 Dihydrolipoamide acetyltransferase 243 6e-64
Hs21630255 [C] KOG0557 Dihydrolipoamide acetyltransferase 234 3e-61
Hs4505699 [C] KOG0557 Dihydrolipoamide acetyltransferase 172 7e-43
At1g34430 [C] KOG0557 Dihydrolipoamide acetyltransferase 166 7e-41
CE15651 [C] KOG0557 Dihydrolipoamide acetyltransferase 162 8e-40
At3g25860 [C] KOG0557 Dihydrolipoamide acetyltransferase 152 1e-36
CE14480 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxog... 122 9e-28
YDR148c [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxog... 121 2e-27
7293036 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto ac... 120 6e-27
Hs19923748 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-o... 116 6e-26
CE01115 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto ac... 116 6e-26
At5g55070 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-ox... 114 4e-25
At3g06850 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto ... 114 4e-25
At4g26910 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-ox... 113 5e-25
7299435 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxog... 105 1e-22
SPBC776.15c [C] KOG0559 Dihydrolipoamide succinyltransferase (2-... 102 1e-21
Hs4503265 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto ... 96 1e-19
YGR193c [C] KOG0557 Dihydrolipoamide acetyltransferase 83 8e-16
SPCC1259.09c [C] KOG0557 Dihydrolipoamide acetyltransferase 81 3e-15
>YNL071w [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 482
Score = 566 bits (1460), Expect = e-161
Identities = 305/488 (62%), Positives = 345/488 (70%), Gaps = 21/488 (4%)
Query: 1 MSALLSRVAPRMS---VLACAARLQLRTYASYPPYTIIGMPALSPTMVQGGLTEWSKNVG 57
MSA + RV PR+S VL + RLQLR YASYP +TIIGMPALSPTM QG L W+K G
Sbjct: 1 MSAFV-RVVPRISRSSVLTRSLRLQLRCYASYPEHTIIGMPALSPTMTQGNLAAWTKKEG 59
Query: 58 DRLEPGDVLAEVETDKAQMDFEFQEEGYLAKILVPAGTKDIPVNKPLAVYVEEESDVPXX 117
D+L PG+V+AE+ETDKAQMDFEFQE+GYLAKILVP GTKDIPVNKP+AVYVE+++DVP
Sbjct: 60 DQLSPGEVIAEIETDKAQMDFEFQEDGYLAKILVPEGTKDIPVNKPIAVYVEDKADVPAF 119
Query: 118 XXXXXXXXXXXXXXXXXXXXXXKQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTRI 177
Q RI
Sbjct: 120 KDFKLEDSGSDSKTSTKAQPAEPQAEKKQEAPAEETKTSAPEAKKSDVAAPQG-----RI 174
Query: 178 FASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAFLXXXXXXXXXXXXXXXXXXXXXX 237
FASPLAK+IALE G+SLK+V GTGPRGRITK D+E++L
Sbjct: 175 FASPLAKTIALEKGISLKDVHGTGPRGRITKADIESYLEKSSKQSSQTSGAAAATPAAAT 234
Query: 238 XXXT------------YEDVPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQS 285
T YEDVPIS MR IIG+RLLQSTQ IPSYIVSS+IS+SKLLKLRQS
Sbjct: 235 SSTTAGSAPSPSSTASYEDVPISTMRSIIGERLLQSTQGIPSYIVSSKISISKLLKLRQS 294
Query: 286 LNATAKDQYKLSINDILIKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGL 345
LNATA D+YKLSIND+L+KAI VAA+R PDANAYW+P + VIRKFKNVDVSVAVATPTGL
Sbjct: 295 LNATANDKYKLSINDLLVKAITVAAKRVPDANAYWLPNENVIRKFKNVDVSVAVATPTGL 354
Query: 346 LTPIVKNAESKGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSII 405
LTPIVKN E+KGL IS EIK+L KRA+ NKL PEEFQGGTICISN+GMN AV+MFTSII
Sbjct: 355 LTPIVKNCEAKGLSQISNEIKELVKRARINKLAPEEFQGGTICISNMGMNNAVNMFTSII 414
Query: 406 NPPQSTILAIGTVNKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVI 465
NPPQSTILAI TV +V VEDA +E GF+FD ++ ITGTFDHRTIDGAKG EFMKELK VI
Sbjct: 415 NPPQSTILAIATVERVAVEDAAAENGFSFDNQVTITGTFDHRTIDGAKGAEFMKELKTVI 474
Query: 466 ENPLELLL 473
ENPLE+LL
Sbjct: 475 ENPLEMLL 482
>SPCC794.07 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 483
Score = 374 bits (960), Expect = e-103
Identities = 202/456 (44%), Positives = 268/456 (58%), Gaps = 21/456 (4%)
Query: 24 RTYAS--YPPYTIIGMPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQ 81
RTYA+ YP +T+I MPALSPTM G + + K +GD++EPGDVL E+ETDKAQ+DFE Q
Sbjct: 43 RTYATKNYPAHTVINMPALSPTMTTGNIGAFQKKIGDKIEPGDVLCEIETDKAQIDFEQQ 102
Query: 82 EEGYLAKILVPAGTKDIPVNKPLAVYVEEESDVPXXXXXXXXXXXXXXXXXXXXXXXXKQ 141
+EGYLAKIL+ GTKD+PV KPLAV VE E DV K+
Sbjct: 103 DEGYLAKILIETGTKDVPVGKPLAVTVENEGDV------------AAMADFTIEDSSAKE 150
Query: 142 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTRIFASPLAKSIALEHGVSLKEVEGTG 201
R+FASPLA+ +A E + L ++ G+G
Sbjct: 151 PSAKSGEEKSAPSSEKQSKETSSPSNVSGEERGDRVFASPLARKLAEEKDLDLSQIRGSG 210
Query: 202 PRGRITKDDVEAFLXXXX----XXXXXXXXXXXXXXXXXXXXXTYEDVPISNMRQIIGDR 257
P GRI K D+E F YED+P+SNMR+II R
Sbjct: 211 PNGRIIKVDIENFKPVVAPKPSNEAAAKATTPAASAADAAAPGDYEDLPLSNMRKIIASR 270
Query: 258 LLQSTQNIPSYIVSSQISVSKLLKLRQSLNATAKDQYKLSINDILIKAIAVAAQRCPDAN 317
L +S P Y V+ +++ K+++LR +LNA A +YKLS+ND++IKA A ++ P+ N
Sbjct: 271 LAESKNMNPHYYVTVSVNMEKIIRLRAALNAMADGRYKLSVNDLVIKATTAALRQVPEVN 330
Query: 318 AYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSISKEIKDLGKRAKDNKL 377
A WM + IR++KNVD+S+AVATP+GL+TP+++N + GL IS KD G+RA++NKL
Sbjct: 331 AAWMGD--FIRQYKNVDISMAVATPSGLITPVIRNTHALGLAEISTLAKDYGQRARNNKL 388
Query: 378 KPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAIGTVNKVPVEDAGSEFGFTFDQK 437
KPEE+QGGT ISNLGM P V FT+IINPPQ+ ILA+GT V D+ SE GF
Sbjct: 389 KPEEYQGGTFTISNLGMFP-VDQFTAIINPPQACILAVGTTVDTVVPDSTSEKGFKVAPI 447
Query: 438 MNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
M T + DHR +DGA F LKK++ENPLE++L
Sbjct: 448 MKCTLSSDHRVVDGAMAARFTTALKKILENPLEIML 483
>CE09597 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 507
Score = 317 bits (811), Expect = 3e-86
Identities = 187/479 (39%), Positives = 259/479 (54%), Gaps = 23/479 (4%)
Query: 2 SALLSRVAPRMSVLACAARLQLRTYAS--YPPYTIIGMPALSPTMVQGGLTEWSKNVGDR 59
S L+ +VA + A + Q+R Y+S P + + +PALSPTM G + W K GD+
Sbjct: 45 SGLVGQVARQYPNAAAFSIKQVRLYSSGNLPKHNRVALPALSPTMELGTVVSWQKKEGDQ 104
Query: 60 LEPGDVLAEVETDKAQMDFEFQEEGYLAKILVPAGTKDIPVNKPLAVYVEEESDVPXXXX 119
L GD+L E+ETDKA M FE EEGYLAKIL+ G+KD+P+ K L + V+ E+DV
Sbjct: 105 LSEGDLLCEIETDKATMGFETPEEGYLAKILIQEGSKDVPIGKLLCIIVDNEADV--AAF 162
Query: 120 XXXXXXXXXXXXXXXXXXXXKQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTRIFA 179
+ R+ A
Sbjct: 163 KDFKDDGASSGGSAPAAEKAPEPAKPAASSQPSPPAQMYQAPSVPKSAPIPHSSSGRVSA 222
Query: 180 SPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAFLXXXXXXXXXXXXXXXXXXXXXXXX 239
SP AK +A E+G+ L V G+GP GRI D+
Sbjct: 223 SPFAKKLAAENGLDLSGVSGSGPGGRILASDLSQ----------APAKGATSTTTQAVSG 272
Query: 240 XTYEDVPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNA-----TAKDQY 294
Y D+P+SNMR+ I RL +S IP Y ++S+I + LL++R+ LN T+
Sbjct: 273 QDYTDIPLSNMRKTIAKRLTESKSTIPHYYLTSEIQLDTLLQVREKLNGLLAKGTSGQAT 332
Query: 295 KLSINDILIKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAE 354
K+SIND +IKA A+A QR P+AN+YWM IR+ +VDVSVAV+TP GL+TPI+ NA
Sbjct: 333 KISINDFIIKASALACQRVPEANSYWM--DSFIRENHHVDVSVAVSTPAGLITPIIFNAH 390
Query: 355 SKGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILA 414
+KGL +I+ EI +L +RA++ KL+P EFQGGT +SNLGM +VS FT+IINPPQS ILA
Sbjct: 391 AKGLATIASEIVELAQRAREGKLQPHEFQGGTFTVSNLGMFGSVSDFTAIINPPQSCILA 450
Query: 415 IGTVNKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
IG + V D G+ + M +T + DHRT+DGA G +++ K+ +E P +LL
Sbjct: 451 IGGASDKLVPDEAE--GYKKIKTMKVTLSCDHRTVDGAVGAVWLRHFKEFLEKPHTMLL 507
>7297250 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 512
Score = 301 bits (772), Expect = 1e-81
Identities = 171/451 (37%), Positives = 243/451 (52%), Gaps = 11/451 (2%)
Query: 24 RTYASYPPYTIIGMPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEE 83
R YA+ P + + +PALSPTM +G + W K GD+L GD+L E+ETDKA M FE EE
Sbjct: 72 RAYANLPEHIRVPLPALSPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPEE 131
Query: 84 GYLAKILVPAGTKDIPVNKPLAVYVEEESDVPXXXXXXXXXXXXXXXXXXXXXXXXKQXX 143
G+LAKIL+ GTKD+PV + L + V ++ V
Sbjct: 132 GFLAKILIQGGTKDVPVGQLLCIIVPDQGSVAAFANFKDDGAAAAPAAPAAAPAPAPAAA 191
Query: 144 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTRIFASPLAKSIALEHGVSLKEVEGTGPR 203
R++ASP+AK +A + L+ +G+G
Sbjct: 192 AAPPPPPPPAAAPAAAAPPPAPAAAPAAAGTGRVYASPMAKRLAEAQQLRLQG-KGSGVH 250
Query: 204 GRITKDDVEAFLXXXXXXXXXXXXXXXXXXXXXXXXXTYEDVPISNMRQIIGDRLLQSTQ 263
G I D+ YED+P++NMR +I RLL+S
Sbjct: 251 GSIKSGDLAG------QKAAAKPAAAAPAKAPRAAGARYEDIPVTNMRAVIAKRLLESKT 304
Query: 264 NIPSYIVSSQISVSKLLKLRQSLNATAKDQ-YKLSINDILIKAIAVAAQRCPDANAYWMP 322
+P Y V+ Q V KLLK R +N + Q ++S+ND +IKA+A+A+ + P+AN+ WM
Sbjct: 305 QLPHYYVTVQCQVDKLLKFRAKVNKKYEKQGARVSVNDFIIKAVAIASLKVPEANSAWMD 364
Query: 323 EQGVIRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSISKEIKDLGKRAKDNKLKPEEF 382
VIRK+ +VDVSVAV+T GL+TPIV NA+ KG++ ISK++K L +A+DNKL+P EF
Sbjct: 365 T--VIRKYDDVDVSVAVSTDKGLITPIVFNADRKGVLEISKDVKALAAKARDNKLQPHEF 422
Query: 383 QGGTICISNLGMNPAVSMFTSIINPPQSTILAIGTVNKVPVEDAGSEFGFTFDQKMNITG 442
QGGTI +SNLGM V+ F ++INPPQS ILAIGT K V D S GF + +T
Sbjct: 423 QGGTISVSNLGMF-GVNQFAAVINPPQSCILAIGTTTKQLVADPDSLKGFKEVNMLTVTL 481
Query: 443 TFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
+ DHR +DGA +++ + +E+P ++L
Sbjct: 482 SADHRVVDGAVAARWLQHFRDYMEDPSNMVL 512
>At3g52200 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 637
Score = 293 bits (749), Expect = 5e-79
Identities = 177/459 (38%), Positives = 237/459 (51%), Gaps = 46/459 (10%)
Query: 30 PPYTIIGMPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEEGYLAKI 89
PP+ ++ MPALSPTM QG + +W K GD++E GDV+ E+ETDKA ++FE EEGYLAKI
Sbjct: 210 PPHVVLEMPALSPTMNQGNIAKWWKKEGDKIEVGDVIGEIETDKATLEFESLEEGYLAKI 269
Query: 90 LVPAGTKDIPVNKPLAVYVEEESDVPXXXXXXXXXXXXXXXXXXXXXXXXKQXXXXXXXX 149
L+P G+KD+ V KP+A+ VE+ + K
Sbjct: 270 LIPEGSKDVAVGKPIALIVEDAESIEAIKSSSAGSSEVDTVKEVPDSVVDKPTERKAGF- 328
Query: 150 XXXXXXXXXXXXXXXXXXXXXXXXXTRIFASPLAKSIALEHGVSLKEVEGTGPRGRITKD 209
T+I SP AK + LEHG+ +E +GP G + K
Sbjct: 329 -------------------------TKI--SPAAKLLILEHGLEASSIEASGPYGTLLKS 361
Query: 210 DVEAFLXXXXXXXXXXXX-------------XXXXXXXXXXXXXTYEDVPISNMRQIIGD 256
DV A + YED P S +R+II
Sbjct: 362 DVVAAIASGKASKSSASTKKKQPSKETPSKSSSTSKPSVTQSDNNYEDFPNSQIRKIIAK 421
Query: 257 RLLQSTQNIPSYIVSSQISVSKLLKLRQSLNATAKDQYKLSINDILIKAIAVAAQRCPDA 316
RLL+S Q IP + S + + LL R+ L K+S+NDI+IKA+AVA + A
Sbjct: 422 RLLESKQKIPHLYLQSDVVLDPLLAFRKELQEN--HGVKVSVNDIVIKAVAVALRNVRQA 479
Query: 317 NAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSISKEIKDLGKRAKDNK 376
NA+W E+G I +VD+S+AVAT GL+TPI+KNA+ K + +IS E+K+L ++A+ K
Sbjct: 480 NAFWDAEKGDIVMCDSVDISIAVATEKGLMTPIIKNADQKSISAISLEVKELAQKARSGK 539
Query: 377 LKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAIGTVNKV--PVEDAGSEFGFTF 434
L P EFQGGT ISNLGM P V F +IINPPQ+ ILA+G NKV PV +
Sbjct: 540 LAPHEFQGGTFSISNLGMYP-VDNFCAIINPPQAGILAVGRGNKVVEPVIGLDGIEKPSV 598
Query: 435 DQKMNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
KMN+T + DHR DG G FM EL+ E+ LLL
Sbjct: 599 VTKMNVTLSADHRIFDGQVGASFMSELRSNFEDVRRLLL 637
Score = 114 bits (284), Expect = 4e-25
Identities = 54/97 (55%), Positives = 73/97 (74%), Gaps = 2/97 (2%)
Query: 20 RLQLRTYASYPPY--TIIGMPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMD 77
R ++ ++S P T++ MPALSPTM G + +W K GD++E GDVL E+ETDKA ++
Sbjct: 71 RFGVQNFSSTGPISQTVLAMPALSPTMSHGNVVKWMKKEGDKVEVGDVLCEIETDKATVE 130
Query: 78 FEFQEEGYLAKILVPAGTKDIPVNKPLAVYVEEESDV 114
FE QEEG+LAKILV G+KDIPVN+P+A+ VEEE D+
Sbjct: 131 FESQEEGFLAKILVTEGSKDIPVNEPIAIMVEEEDDI 167
>At3g13930 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 508
Score = 292 bits (748), Expect = 6e-79
Identities = 173/469 (36%), Positives = 250/469 (52%), Gaps = 29/469 (6%)
Query: 14 VLACAARLQLRT------YASY-PPYTIIGMPALSPTMVQGGLTEWSKNVGDRLEPGDVL 66
V+ R+QL T Y +Y PP+ IGMP+LSPTM +G + W K GD++ PG+VL
Sbjct: 60 VIHLPMRIQLATFLYEYFYPNYLPPHQEIGMPSLSPTMTEGNIARWLKKEGDKVAPGEVL 119
Query: 67 AEVETDKAQMDFEFQEEGYLAKILVPAGTKDIPVNKPLAVYVEEESDVPXXXXXXXXXXX 126
EVETDKA ++ E EEG+LAKI+ G K+I V + +A+ VE+E D+
Sbjct: 120 CEVETDKATVEMECMEEGFLAKIVKEEGAKEIQVGEVIAITVEDEDDIQKFKDYTPSSDT 179
Query: 127 XXXXXXXXXXXXXKQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTRIFASPLAKSI 186
+ RIFASPLA+ +
Sbjct: 180 GPAA---------PEAKPAPSLPKEEKVEKPASAPEAKISKPSSAPSEDRIFASPLARKL 230
Query: 187 ALEHGVSLKEVEGTGPRGRITKDDVEAFLXXXXXXXXXXXXXXXXXXXXXXXXXTYEDVP 246
A ++ V L ++GTGP GRI K DVE FL Y D+P
Sbjct: 231 AEDNNVPLSSIKGTGPEGRIVKADVEDFLETTAKPSKQVDSKVPALD--------YVDIP 282
Query: 247 ISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNA--TAKDQYKLSINDILIK 304
+ +R++ RL S Q IP Y ++ V K++ LR LN+ A ++S+ND++IK
Sbjct: 283 HTQIRKVTASRLAFSKQTIPHYYLTVDTCVDKMMGLRSQLNSFQEASGGKRISVNDLVIK 342
Query: 305 AIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSISKE 364
A A+A ++ P N+ W E IR+FKNV+++VAV T GL P+VK+A+ KGL +I +E
Sbjct: 343 AAALALRKVPQCNSSWTDEY--IRQFKNVNINVAVQTENGLYVPVVKDADKKGLSTIGEE 400
Query: 365 IKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAIGTVNKVPVE 424
++ L ++AK+N LKPE+++GGT +SNLG + F ++INPPQ+ ILAIG+ K V
Sbjct: 401 VRFLAQKAKENSLKPEDYEGGTFTVSNLGGPFGIKQFCAVINPPQAAILAIGSAEKRVVP 460
Query: 425 DAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
G + + M++T + DHR IDGA G E++K K IE P +LL
Sbjct: 461 GTGPD-QYNVASYMSVTLSCDHRVIDGAIGAEWLKAFKGYIETPESMLL 508
>At1g54220 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 424
Score = 279 bits (714), Expect = 6e-75
Identities = 160/440 (36%), Positives = 237/440 (53%), Gaps = 19/440 (4%)
Query: 37 MPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEEGYLAKILVPAGTK 96
MP+LSPTM +G + W K GD++ PG+VL EVETDKA ++ E EEGYLAKI+ G+K
Sbjct: 1 MPSLSPTMTEGNIARWLKKEGDKVAPGEVLCEVETDKATVEMECMEEGYLAKIVKAEGSK 60
Query: 97 DIPVNKPLAVYV-EEESDVPXXXXXXXXXXXXXXXXXXXXXXXXKQXXXXXXXXXXXXXX 155
+I V + +A+ V +EE K+
Sbjct: 61 EIQVGEVIAITVEDEEDIGKFKDYTPSSTADAAPTKAEPTPAPPKEEKVKQPSSPPEPKA 120
Query: 156 XXXXXXXXXXXXXXXXXXXTRIFASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAFL 215
R+FASPLA+ +A ++ V L ++EGTGP GRI K D++ +L
Sbjct: 121 SKPSTPPTGD----------RVFASPLARKLAEDNNVPLSDIEGTGPEGRIVKADIDEYL 170
Query: 216 XXXXXXXXXXXXXXXXXXXXXXXXXTYEDVPISNMRQIIGDRLLQSTQNIPSYIVSSQIS 275
Y D+P S +R++ RL S Q IP Y ++
Sbjct: 171 ASSGKGATAKPSKSTDSKAPALD---YVDIPHSQIRKVTASRLAFSKQTIPHYYLTVDTC 227
Query: 276 VSKLLKLRQSLNA--TAKDQYKLSINDILIKAIAVAAQRCPDANAYWMPEQGVIRKFKNV 333
V KL+ LR LN+ A ++S+ND+++KA A+A ++ P N+ W + IR+FKNV
Sbjct: 228 VDKLMALRSQLNSFKEASGGKRISVNDLVVKAAALALRKVPQCNSSWTDDY--IRQFKNV 285
Query: 334 DVSVAVATPTGLLTPIVKNAESKGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLG 393
+++VAV T GL P+VK+A+ KGL +I +E++ L ++AK+N LKPE+++GGT +SNLG
Sbjct: 286 NINVAVQTENGLYVPVVKDADRKGLSTIGEEVRLLAQKAKENSLKPEDYEGGTFTVSNLG 345
Query: 394 MNPAVSMFTSIINPPQSTILAIGTVNKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAK 453
+ F +++NPPQ+ ILA+G+ K V G + F F M +T + DHR +DGA
Sbjct: 346 GPFGIKQFCAVVNPPQAAILAVGSAEKRVVPGNGPD-QFNFASYMPVTLSCDHRVVDGAI 404
Query: 454 GGEFMKELKKVIENPLELLL 473
G E++K K IENP +LL
Sbjct: 405 GAEWLKAFKGYIENPKSMLL 424
>Hs17458911 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 647
Score = 243 bits (619), Expect = 6e-64
Identities = 128/298 (42%), Positives = 192/298 (63%), Gaps = 4/298 (1%)
Query: 176 RIFASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAFLXXXXXXXXXXXXXXXXXXXX 235
R+F SPLAK +A+E G+ L +V+GTGP GRITK D+++F+
Sbjct: 354 RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMA 413
Query: 236 XXXXXTYEDVPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNATAKDQYK 295
+ D+PISN+R++I RL+QS Q IP Y +S +++ ++L +R+ LN + + K
Sbjct: 414 PVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRSK 473
Query: 296 LSINDILIKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAES 355
+S+ND +IKA A+A + P+AN+ WM VIR+ VDVSVAV+TP GL+TPIV NA
Sbjct: 474 ISVNDFIIKASALACLKVPEANSSWMDT--VIRQNHVVDVSVAVSTPAGLITPIVFNAHI 531
Query: 356 KGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAI 415
KG+ +I+ ++ L +A++ KL+P EFQGGT ISNLGM + F++IINPPQ+ ILAI
Sbjct: 532 KGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMF-GIKNFSAIINPPQACILAI 590
Query: 416 GTVNKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
G ++ + A +E GF M++T + DHR +DGA G +++ E +K +E P+ +LL
Sbjct: 591 G-ASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL 647
Score = 115 bits (287), Expect = 2e-25
Identities = 51/88 (57%), Positives = 68/88 (76%)
Query: 27 ASYPPYTIIGMPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEEGYL 86
+SYPP+ + +PALSPTM G + W K VG++L GD+LAE+ETDKA + FE QEEGYL
Sbjct: 213 SSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYL 272
Query: 87 AKILVPAGTKDIPVNKPLAVYVEEESDV 114
AKILVP GT+D+P+ PL + VE+E+D+
Sbjct: 273 AKILVPEGTRDVPLGTPLCIIVEKEADI 300
Score = 92.4 bits (228), Expect = 1e-18
Identities = 46/109 (42%), Positives = 65/109 (59%)
Query: 6 SRVAPRMSVLACAARLQLRTYASYPPYTIIGMPALSPTMVQGGLTEWSKNVGDRLEPGDV 65
S PR +L R Y S PP+ + +P+LSPTM G + W K GD++ GD+
Sbjct: 65 SGATPRNRLLLQLLGSPGRRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDQINEGDL 124
Query: 66 LAEVETDKAQMDFEFQEEGYLAKILVPAGTKDIPVNKPLAVYVEEESDV 114
+AEVETDKA + FE EE Y+AKILV GT+D+P+ + + V + D+
Sbjct: 125 IAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDI 173
>Hs21630255 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 613
Score = 234 bits (596), Expect = 3e-61
Identities = 127/298 (42%), Positives = 188/298 (62%), Gaps = 5/298 (1%)
Query: 176 RIFASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAFLXXXXXXXXXXXXXXXXXXXX 235
R+F PLAK +A+E G+ L +V+GTGP GRITK D+++F+
Sbjct: 321 RVFVDPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMA 380
Query: 236 XXXXXTYEDVPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNATAKDQYK 295
+ D+PISN+R++I RL+QS Q IP Y + S ++L +R+ LN + + K
Sbjct: 381 PVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLLS-CKYGEVLLVRKELNKILEGRSK 439
Query: 296 LSINDILIKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAES 355
+S+ND +IKA A+A + P+AN+ WM VIR+ VDVSVAV+TP GL+TPIV NA
Sbjct: 440 ISVNDFIIKASALACLKVPEANSSWMDT--VIRQNHVVDVSVAVSTPAGLITPIVFNAHI 497
Query: 356 KGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAI 415
KG+ +I+ ++ L +A++ KL+P EFQGGT ISNLGM + F++IINPPQ+ ILAI
Sbjct: 498 KGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMF-GIKNFSAIINPPQACILAI 556
Query: 416 GTVNKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
G ++ + A +E GF M++T + DHR +DGA G +++ E +K +E P+ +LL
Sbjct: 557 G-ASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL 613
Score = 115 bits (287), Expect = 2e-25
Identities = 51/88 (57%), Positives = 68/88 (76%)
Query: 27 ASYPPYTIIGMPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEEGYL 86
+SYPP+ + +PALSPTM G + W K VG++L GD+LAE+ETDKA + FE QEEGYL
Sbjct: 180 SSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYL 239
Query: 87 AKILVPAGTKDIPVNKPLAVYVEEESDV 114
AKILVP GT+D+P+ PL + VE+E+D+
Sbjct: 240 AKILVPEGTRDVPLGTPLCIIVEKEADI 267
Score = 92.4 bits (228), Expect = 1e-18
Identities = 42/91 (46%), Positives = 60/91 (65%)
Query: 24 RTYASYPPYTIIGMPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEE 83
R Y S PP+ + +P+LSPTM G + W K GD++ GD++AEVETDKA + FE EE
Sbjct: 50 RRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEE 109
Query: 84 GYLAKILVPAGTKDIPVNKPLAVYVEEESDV 114
Y+AKILV GT+D+P+ + + V + D+
Sbjct: 110 CYMAKILVAEGTRDVPIGAIICITVGKPEDI 140
>Hs4505699 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 501
Score = 172 bits (437), Expect = 7e-43
Identities = 108/326 (33%), Positives = 159/326 (48%), Gaps = 36/326 (11%)
Query: 176 RIFASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAFLXXXXXXXXXXXXXXXXXXXX 235
R SP A++I +H + + TGPRG TK+D +
Sbjct: 181 RFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTAT 240
Query: 236 XXXXX----------------------------TYEDVPISNMRQIIGDRLLQSTQNIPS 267
T+ ++P SN+R++I RL +S +P
Sbjct: 241 PTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPH 300
Query: 268 YIVSSQISVSKLLKLRQSLNATAKDQYKLSINDILIKAIAVAAQRCPDANAYWMPEQGVI 327
++ + +LK+RQ L KD K+S+ND +IKA AV ++ PD N W E
Sbjct: 301 AYATADCDLGAVLKVRQDL---VKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGP-- 355
Query: 328 RKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSISKEIKDLGKRAKDNKLKPEEFQGGTI 387
++ +D+SVAVAT GLLTPI+K+A +KG+ I+ +K L K+A+D KL PEE+QGG+
Sbjct: 356 KQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSF 415
Query: 388 CISNLGMNPAVSMFTSIINPPQSTILAIGTVNKV--PVEDAGSEFGFTFDQKMNITGTFD 445
ISNLGM + FT++INPPQ+ ILA+G V ED Q + +T + D
Sbjct: 416 SISNLGMF-GIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSD 474
Query: 446 HRTIDGAKGGEFMKELKKVIENPLEL 471
R +D F+K K +ENP+ L
Sbjct: 475 SRVVDDELATRFLKSFKANLENPIRL 500
Score = 72.0 bits (175), Expect = 2e-12
Identities = 33/77 (42%), Positives = 50/77 (64%)
Query: 37 MPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEEGYLAKILVPAGTK 96
MP+LSPTM +G + +W K G+ + GD L E+ETDKA + + ++G LAKI+V G+K
Sbjct: 61 MPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSK 120
Query: 97 DIPVNKPLAVYVEEESD 113
+I + + + VEE D
Sbjct: 121 NIRLGSLIGLIVEEGED 137
>At1g34430 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 465
Score = 166 bits (420), Expect = 7e-41
Identities = 122/437 (27%), Positives = 192/437 (43%), Gaps = 15/437 (3%)
Query: 35 IGMPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEEGYLAKILVPAG 94
I MPALS TM +G + W K+ GD+L G+ + VE+DKA MD E +GYLA I+V G
Sbjct: 42 IFMPALSSTMTEGKIVSWVKSEGDKLNKGESVVVVESDKADMDVETFYDGYLAAIMVEEG 101
Query: 95 TKDIPVNKPLAVYVEEESDVPXXXXXXXXXXXXXXXXXXXXXXXXKQXXXXXXXXXXXXX 154
PV +A+ E E ++
Sbjct: 102 GV-APVGSAIALLAETEDEIADAKAKASGGGGGGDSKAPPASPPTAAVEAPVSVEKKVAA 160
Query: 155 XXXXXXXXXXXXXXXXXXXXTRIFASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAF 214
RI ASP AK +A E V L + G+GP GRI DVEA
Sbjct: 161 APVSIKAVAASAVHPASEGGKRIVASPYAKKLAKELKVELAGLVGSGPMGRIVAKDVEAV 220
Query: 215 LXXXXXXXXXXXXXXXXXXXXXXXXXTYEDVPISNMRQIIGDRLLQSTQNIPSYIVSSQI 274
VP + M+ + +++S +P++ V I
Sbjct: 221 AAGGGVQAAVAVKEVVAAPGVELGSV----VPFTTMQGAVSRNMVESL-GVPTFRVGYTI 275
Query: 275 SVSKLLKLRQSLNATAKDQYKLSINDILIKAIAVAAQRCPDANAYWMPEQGVIRKFKNVD 334
S L L + + + +++ +L KA A+A + P N+ + +++
Sbjct: 276 STDALDALYKKIKSKG-----VTMTALLAKATALALAKHPVVNSSCRDGNSFVYN-SSIN 329
Query: 335 VSVAVATPTGLLTPIVKNAESKGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGM 394
V+VAVA GL+TP+++NA+ + S+S++ K+L +A+ +L+P+E+ GT +SNLGM
Sbjct: 330 VAVAVAIDGGLITPVLQNADKVDIYSLSRKWKELVDKARAKQLQPQEYNTGTFTLSNLGM 389
Query: 395 NPAVSMFTSIINPPQSTILAIGTVNKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKG 454
V F +I+ P I+A+G V G ++N+T DHR I GA
Sbjct: 390 F-GVDRFDAILPPGTGAIMAVGASQPSVVATKDGRIGMKNQMQVNVTA--DHRVIYGADL 446
Query: 455 GEFMKELKKVIENPLEL 471
+F++ L +IE+P +L
Sbjct: 447 AQFLQTLASIIEDPKDL 463
>CE15651 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 337
Score = 162 bits (411), Expect = 8e-40
Identities = 105/309 (33%), Positives = 159/309 (50%), Gaps = 26/309 (8%)
Query: 181 PLAKSIALEHGVSLKEVEGTGPRGR-ITKDDVEAFLXX---------------XXXXXXX 224
P K + +++G+ ++++GTGP+ + I K DV +
Sbjct: 23 PAVKLLLIQYGLENRKIDGTGPKNKNILKGDVMKIVEAEKLKPVAHHAHAPKETHIENKS 82
Query: 225 XXXXXXXXXXXXXXXXTYEDVPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQ 284
++D+P+SN+R I RL S Q IP + + +L LRQ
Sbjct: 83 IEKKSDIFGANNRSLRHHQDIPLSNIRATIAKRLTASKQQIPHEYQGVDVRIDDILALRQ 142
Query: 285 SLNATAKDQYKLSINDILIKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTG 344
L K +S+ND +IKA A+A + P N W PE G+ +VD+SVAVATPTG
Sbjct: 143 KLK---KSGTAVSLNDFIIKAAALALRSVPTVNVRWTPE-GI--GLGSVDISVAVATPTG 196
Query: 345 LLTPIVKNAESKGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSI 404
L+TPIV+N++ G+++IS ++K+L A+++KLKP++FQGG+ ISNLGM +V+ FT+I
Sbjct: 197 LITPIVENSDILGVLAISSKVKELSGLARESKLKPQQFQGGSFTISNLGMFGSVTNFTAI 256
Query: 405 INPPQSTILAIGTVNKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKV 464
INPPQ IL IG V G + M + FD R I F+ +
Sbjct: 257 INPPQCAILTIGGTRSEVVSVDGQ---LETQKLMGVNLCFDGRAISEECAKRFLLHFSES 313
Query: 465 IENPLELLL 473
+ +P ELL+
Sbjct: 314 LSDP-ELLI 321
>At3g25860 [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 480
Score = 152 bits (383), Expect = 1e-36
Identities = 118/447 (26%), Positives = 191/447 (42%), Gaps = 32/447 (7%)
Query: 35 IGMPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEEGYLAKILVPAG 94
I MPALS TM +G + W K G++L G+ + VE+DKA MD E +GYLA I+V G
Sbjct: 58 IFMPALSSTMTEGKIVSWIKTEGEKLAKGESVVVVESDKADMDVETFYDGYLAAIVVGEG 117
Query: 95 TKDIPVNKPLAVYVEEESDVPXXXXXXXXXXXXXXXXXXXXXXXXKQXXXXXXXXXXXXX 154
+ PV + + E E+++
Sbjct: 118 -ETAPVGAAIGLLAETEAEIEEAKSKAASKSSSSVAEAVVPSPPP-------------VT 163
Query: 155 XXXXXXXXXXXXXXXXXXXXTRIFASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAF 214
+ A+P AK +A +H V ++ V GTGP GRIT DVE
Sbjct: 164 SSPAPAIAQPAPVTAVSDGPRKTVATPYAKKLAKQHKVDIESVAGTGPFGRITASDVETA 223
Query: 215 LXXXXXXXXXXXXXXXXXXXXXXXXXTY--------EDVPISNMRQIIGDRLLQSTQNIP 266
T VP + M+ + +++S ++P
Sbjct: 224 AGIAPSKSSIAPPPPPPPPVTAKATTTNLPPLLPDSSIVPFTAMQSAVSKNMIESL-SVP 282
Query: 267 SYIVSSQISVSKLLKLRQSLNATAKDQYKLSINDILIKAIAVAAQRCPDANAYWMPEQGV 326
++ V ++ L L + + +++ +L KA +A + P NA +
Sbjct: 283 TFRVGYPVNTDALDALYEKVKPKG-----VTMTALLAKAAGMALAQHPVVNASCKDGKSF 337
Query: 327 IRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSISKEIKDLGKRAKDNKLKPEEFQGGT 386
+++++VAVA GL+TP++++A+ L +S++ K+L +A+ +L+P E+ GT
Sbjct: 338 SYN-SSINIAVAVAINGGLITPVLQDADKLDLYLLSQKWKELVGKARSKQLQPHEYNSGT 396
Query: 387 ICISNLGMNPAVSMFTSIINPPQSTILAIGTVNKVPVEDAGSEFGFTFDQKMNITGTFDH 446
+SNLGM V F +I+ P Q I+A+G V D F +N+T DH
Sbjct: 397 FTLSNLGMF-GVDRFDAILPPGQGAIMAVGASKPTVVADKDGFFSVKNTMLVNVTA--DH 453
Query: 447 RTIDGAKGGEFMKELKKVIENPLELLL 473
R + GA F++ K+IENP L L
Sbjct: 454 RIVYGADLAAFLQTFAKIIENPDSLTL 480
>CE14480 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxoglutarate
dehydrogenase E2 subunit)
Length = 452
Score = 122 bits (307), Expect = 9e-28
Identities = 83/227 (36%), Positives = 118/227 (51%), Gaps = 21/227 (9%)
Query: 245 VPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNA--TAKDQYKLSINDIL 302
V + MR I RL + ++I +S L+++R++ AK KL +
Sbjct: 237 VKANRMRMRIAQRLKDAQNTYAMLTTFNEIDMSSLIEMRKTYQKDFVAKHGVKLGMMSPF 296
Query: 303 IKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSIS 362
++A A A Q P NA + V R F VD+SVAVATP GL+ P+++N ES I
Sbjct: 297 VRAAAYALQESPVVNAVLDENEIVYRHF--VDISVAVATPKGLVVPVLRNVESMNYAQIE 354
Query: 363 KEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMF-TSIINPPQSTILAIGTVNKV 421
E+ +LG +A+D KL E+ +GGT ISN G+ SMF T IINPPQS IL +
Sbjct: 355 LELANLGVKARDGKLAVEDMEGGTFTISNGGV--FGSMFGTPIINPPQSAILGMHGPEIR 412
Query: 422 PVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENP 468
P+ M I T+DHR IDG + F+K++K +E+P
Sbjct: 413 PI--------------MQIALTYDHRLIDGREAVTFLKKIKTAVEDP 445
>YDR148c [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxoglutarate
dehydrogenase E2 subunit)
Length = 463
Score = 121 bits (304), Expect = 2e-27
Identities = 81/231 (35%), Positives = 125/231 (54%), Gaps = 8/231 (3%)
Query: 245 VPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLN--ATAKDQYKLSINDIL 302
V ++ MR I +RL +S S +++ +S L+++R+ K K +
Sbjct: 238 VKMNRMRLRIAERLKESQNTAASLTTFNEVDMSALMEMRKLYKDEIIKKTGTKFGFMGLF 297
Query: 303 IKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSIS 362
KA +AA+ P N +Q V R + D+SVAVATP GL+TP+V+NAES ++ I
Sbjct: 298 SKACTLAAKDIPAVNGAIEGDQIVYRDY--TDISVAVATPKGLVTPVVRNAESLSVLDIE 355
Query: 363 KEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAIGTVNKVP 422
EI L +A+D KL E+ GGT ISN G+ ++ T IIN PQ+ +L + V + P
Sbjct: 356 NEIVRLSHKARDGKLTLEDMTGGTFTISNGGVFGSL-YGTPIINSPQTAVLGLHGVKERP 414
Query: 423 VEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
V G M + T+DHR +DG + F+K +K++IE+P ++LL
Sbjct: 415 VTVNGQ---IVSRPMMYLALTYDHRLLDGREAVTFLKTVKELIEDPRKMLL 462
>7293036 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto acid
dehydrogenase E2 subunit)
Length = 462
Score = 120 bits (300), Expect = 6e-27
Identities = 109/434 (25%), Positives = 178/434 (40%), Gaps = 40/434 (9%)
Query: 51 EWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEEGYLAKILVPAGTKDIPVNKPLAVY--V 108
EW GD +E D L EV++DKA + + +G + KI + V KPL + V
Sbjct: 57 EWFVKEGDTVEQFDNLCEVQSDKASVTITSRYDGKITKIHHKIDEIAL-VGKPLLDFDVV 115
Query: 109 EEESDVPXXXXXXXXXXXXXXXXXXXXXXXXKQXXXXXXXXXXXXXXXXXXXXXXXXXXX 168
E+ D P +
Sbjct: 116 NEDEDEPEDSSSSSSSTSSDSSASENEEKQSAEASATPTEGRVI---------------- 159
Query: 169 XXXXXXTRIFASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAFLXXXXXXXXXXXXX 228
I A+P + +A EH + L +V TG GR+ K D+ FL
Sbjct: 160 --------IPATPSVRRLAKEHQLDLAKVPATGKNGRVLKGDILEFLGQVPPGTNVPHPT 211
Query: 229 XXXXXXXXXXXXTYE-DVPISNMRQIIGDR--LLQS---TQNIPSYIVSSQISVSKLLKL 282
VP + + G R +L+S + IP + S +I +++L++
Sbjct: 212 LLAKTPSAAPSGAASVSVPADRVEVLKGVRKAMLKSMTESLKIPHFAYSDEIDMTQLMQF 271
Query: 283 RQSLNATAKDQY--KLSINDILIKAIAVAAQRCPDANAYW-MPEQGVIRKFKNVDVSVAV 339
R L AK+ KL+ IKA ++A + P N+ + + ++ K + ++SVA+
Sbjct: 272 RNQLQLVAKENGVPKLTFMPFCIKAASIALSKYPIVNSSLDLASESLVFKGAH-NISVAI 330
Query: 340 ATPTGLLTPIVKNAESKGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVS 399
TP GL+ P +KN ++K ++ I+K++ L +R + L P +F GT +SN+G+
Sbjct: 331 DTPQGLVVPNIKNCQTKTIIEIAKDLNALVERGRTGSLSPADFADGTFSLSNIGVIGGTY 390
Query: 400 MFTSIINPPQSTILAIGTVNKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMK 459
I+ PQ I A+G VP + E + M+++ + DHR IDG F
Sbjct: 391 THPCIM-APQVAIGAMGRTKAVPRFNDKDEVVKAY--VMSVSWSADHRVIDGVTMASFSN 447
Query: 460 ELKKVIENPLELLL 473
K+ +ENP LL
Sbjct: 448 VWKQYLENPALFLL 461
>Hs19923748 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxoglutarate
dehydrogenase E2 subunit)
Length = 453
Score = 116 bits (291), Expect = 6e-26
Identities = 76/229 (33%), Positives = 116/229 (50%), Gaps = 6/229 (2%)
Query: 247 ISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNAT--AKDQYKLSINDILIK 304
++ MRQ I RL ++ ++I +S + ++R K KL +K
Sbjct: 227 MNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVK 286
Query: 305 AIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSISKE 364
A A A Q P NA + +D+SVAVATP GL+ P+++N E+ I +
Sbjct: 287 ASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEAMNFADIERT 346
Query: 365 IKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAIGTVNKVPVE 424
I +LG++A+ N+L E+ GGT ISN G+ ++ T IINPPQS IL + + PV
Sbjct: 347 ITELGEKARKNELAIEDMDGGTFTISNGGVFGSL-FGTPIINPPQSAILGMHGIFDRPVA 405
Query: 425 DAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
G M + T+DHR IDG + F++++K +E+P LLL
Sbjct: 406 IGGK---VEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLL 451
>CE01115 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto acid
dehydrogenase E2 subunit)
Length = 448
Score = 116 bits (291), Expect = 6e-26
Identities = 88/306 (28%), Positives = 147/306 (47%), Gaps = 14/306 (4%)
Query: 176 RIFASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAFLXXXXXXXXXXXXXXXXXXXX 235
++ A+P + IA+E+ + L EV GTG GR+ K+DV FL
Sbjct: 144 KVLATPAVRRIAIENKIKLAEVRGTGKDGRVLKEDVLKFLGQVPADHTSGSTNIRTTHQA 203
Query: 236 XX-XXXTYED------VPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNA 288
+YE VPI + + + ++ + IP + + +I+V L+K R L
Sbjct: 204 PQPSSKSYEPLKEDVAVPIRGYTRAMVKTMTEALK-IPHFGYNDEINVDSLVKYRAELKE 262
Query: 289 TAKDQY-KLSINDILIKAIAVAAQRCPDANAYWMPE-QGVIRKFKNVDVSVAVATPTGLL 346
AK+++ KLS IKA ++A P N+ + + VI K + ++ +A+ TP GL+
Sbjct: 263 FAKERHIKLSYMPFFIKAASLALLEYPSLNSTTDEKMENVIHKASH-NICLAMDTPGGLV 321
Query: 347 TPIVKNAESKGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIIN 406
P +KN E + + I++E+ L + K ++K E+ GT +SN+G N + + ++
Sbjct: 322 VPNIKNCEQRSIFEIAQELNRLLEAGKKQQIKREDLIDGTFSLSNIG-NIGGTYASPVVF 380
Query: 407 PPQSTILAIGTVNKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIE 466
PPQ I AIG + K+P D M ++ DHR +DGA F K +E
Sbjct: 381 PPQVAIGAIGKIEKLPRFD--KHDNVIPVNIMKVSWCADHRVVDGATMARFSNRWKFYLE 438
Query: 467 NPLELL 472
+P +L
Sbjct: 439 HPSAML 444
>At5g55070 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxoglutarate
dehydrogenase E2 subunit)
Length = 464
Score = 114 bits (284), Expect = 4e-25
Identities = 72/231 (31%), Positives = 121/231 (52%), Gaps = 8/231 (3%)
Query: 245 VPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNATAKDQY--KLSINDIL 302
VP++ +R+ + RL S +++ ++ L+KLR +++ KL +
Sbjct: 238 VPMTRLRKRVATRLKDSQNTFALLTTFNEVDMTNLMKLRSQYKDAFLEKHGVKLGLMSGF 297
Query: 303 IKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSIS 362
IKA A Q P NA + + R + VD+S+AV T GL+ P++++A+ I
Sbjct: 298 IKAAVSALQHQPVVNAVIDGDDIIYRDY--VDISIAVGTSKGLVVPVIRDADKMNFADIE 355
Query: 363 KEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAIGTVNKVP 422
K I L K+A + + +E GG+ +SN G+ ++ + T IINPPQS IL + ++ + P
Sbjct: 356 KTINGLAKKATEGTISIDEMAGGSFTVSNGGVYGSL-ISTPIINPPQSAILGMHSIVQRP 414
Query: 423 VEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
+ GS M + T+DHR IDG + F++ +K V+E+P LLL
Sbjct: 415 MVVGGS---VVPRPMMYVALTYDHRLIDGREAVYFLRRIKDVVEDPQRLLL 462
>At3g06850 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto acid
dehydrogenase E2 subunit)
Length = 483
Score = 114 bits (284), Expect = 4e-25
Identities = 83/302 (27%), Positives = 145/302 (47%), Gaps = 12/302 (3%)
Query: 179 ASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAFLXXXXXXXXXXXXXXXXX---XXX 235
++P +++A + G+ + + GTG GR+ K+DV F
Sbjct: 184 STPAVRNLAKDLGIDINVITGTGKDGRVLKEDVLRFSDQKGFVTDSVSSEHAVIGGDSVS 243
Query: 236 XXXXXTYED--VPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNATAKDQ 293
+ED VP+ + + + +T ++P + +I+ L++L+Q D
Sbjct: 244 TKASSNFEDKTVPLRGFSRAMVKTMTMAT-SVPHFHFVEEINCDSLVELKQFFKENNTDS 302
Query: 294 -YKLSINDILIKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKN 352
K + LIK++++A + P N+ + E I + ++ VA+AT GL+ P +KN
Sbjct: 303 TIKHTFLPTLIKSLSMALTKYPFVNSCFNAESLEIILKGSHNIGVAMATEHGLVVPNIKN 362
Query: 353 AESKGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTI 412
+S L+ I+KE+ L A +NKL PE+ GGTI +SN+G + ++N P+ I
Sbjct: 363 VQSLSLLEITKELSRLQHLAANNKLNPEDVTGGTITLSNIGAIGG-KFGSPLLNLPEVAI 421
Query: 413 LAIGTVNKVPVEDAGSEFGFTFDQK-MNITGTFDHRTIDGAKGGEFMKELKKVIENPLEL 471
+A+G + KVP S+ G + M + DHR +DGA F + K+ +E P L
Sbjct: 422 IALGRIEKVP---KFSKEGTVYPASIMMVNIAADHRVLDGATVARFCCQWKEYVEKPELL 478
Query: 472 LL 473
+L
Sbjct: 479 ML 480
>At4g26910 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxoglutarate
dehydrogenase E2 subunit)
Length = 511
Score = 113 bits (283), Expect = 5e-25
Identities = 72/231 (31%), Positives = 119/231 (51%), Gaps = 8/231 (3%)
Query: 245 VPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNATAKDQY--KLSINDIL 302
VP++ +R+ + RL S +++ ++ L+KLR +++ KL +
Sbjct: 285 VPMTRLRKRVATRLKDSQNTFALLTTFNEVDMTNLMKLRSQYKDAFYEKHGVKLGLMSGF 344
Query: 303 IKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSIS 362
IKA A Q P NA + + R + VD+S+AV T GL+ P+++ A+ I
Sbjct: 345 IKAAVSALQHQPVVNAVIDGDDIIYRDY--VDISIAVGTSKGLVVPVIRGADKMNFAEIE 402
Query: 363 KEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAIGTVNKVP 422
K I L K+A + + +E GG+ +SN G+ ++ + T IINPPQS IL + ++ P
Sbjct: 403 KTINSLAKKANEGTISIDEMAGGSFTVSNGGVYGSL-ISTPIINPPQSAILGMHSIVSRP 461
Query: 423 VEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
+ GS M + T+DHR IDG + F++ +K V+E+P LLL
Sbjct: 462 MVVGGS---VVPRPMMYVALTYDHRLIDGREAVYFLRRVKDVVEDPQRLLL 509
>7299435 [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxoglutarate
dehydrogenase E2 subunit)
Length = 468
Score = 105 bits (262), Expect = 1e-22
Identities = 77/226 (34%), Positives = 113/226 (49%), Gaps = 8/226 (3%)
Query: 245 VPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLR-QSLNA-TAKDQYKLSINDIL 302
V ++ MR I RL + +++ +S + R Q+L+A T K K I
Sbjct: 242 VKMNRMRLKIAARLKDAQNTCAMLTTFNEVDMSYAMDFRKQNLDAFTKKYGIKFGFMSIF 301
Query: 303 IKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVATPTGLLTPIVKNAESKGLVSIS 362
KA A A Q P NA V R + VD+SVAVATP GL+ P+++N E I
Sbjct: 302 AKASAYALQDQPVVNAVIDGTDIVYRDY--VDISVAVATPRGLVVPVIRNVEGMNYADIE 359
Query: 363 KEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAIGTVNKVP 422
+ L +A+ + + E+ GGT ISN G+ ++ M T IINPPQS IL + + + P
Sbjct: 360 IALAGLADKARRDAITVEDMDGGTFTISNGGVFGSL-MGTPIINPPQSAILGMHGIFERP 418
Query: 423 VEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENP 468
+ G M I T+DHR IDG + F++++K +ENP
Sbjct: 419 IAVKGE---VKIRPMMYIALTYDHRIIDGREAVLFLRKIKAAVENP 461
>SPBC776.15c [C] KOG0559 Dihydrolipoamide succinyltransferase (2-oxoglutarate
dehydrogenase E2 subunit)
Length = 452
Score = 102 bits (254), Expect = 1e-21
Identities = 75/235 (31%), Positives = 118/235 (49%), Gaps = 12/235 (5%)
Query: 245 VPISNMRQIIGDRLLQSTQNIPSYIVSSQISVSKLLKLRQSLNATAKDQ--YKLSINDIL 302
V ++ MR I +RL +S S ++ +S ++ LR+ + K+
Sbjct: 223 VKMNRMRLRIAERLKESQNRAASLTTFNECDMSAVVALRKKYKDEILKETGVKIGFMSFF 282
Query: 303 IKAIAVAAQRCPDANAYWMPEQG----VIRKFKNVDVSVAVATPTGLLTPIVKNAESKGL 358
KA A ++ P N E V R F D+S+AVATP GL+TP+++NAES L
Sbjct: 283 SKACTQAMKQIPAINGSIEGEGKGDTLVYRDF--CDLSIAVATPKGLVTPVIRNAESMSL 340
Query: 359 VSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSMFTSIINPPQSTILAIGTV 418
+ I I LG +A+ KL E+ GT ISN G+ ++ T IIN PQ+ +L + +
Sbjct: 341 LEIESAIATLGSKARAGKLAIEDMASGTFTISNGGIFGSL-YGTPIINLPQTAVLGLHAI 399
Query: 419 NKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKELKKVIENPLELLL 473
+ PV G M + T+DHR +DG + F++ +K+ IE+P ++LL
Sbjct: 400 KERPVVINGQ---VVPRPMMYLALTYDHRMVDGREAVTFLRLVKEYIEDPAKMLL 451
>Hs4503265 [C] KOG0558 Dihydrolipoamide transacylase (alpha-keto acid
dehydrogenase E2 subunit)
Length = 482
Score = 95.9 bits (237), Expect = 1e-19
Identities = 79/313 (25%), Positives = 135/313 (42%), Gaps = 18/313 (5%)
Query: 176 RIFASPLAKSIALEHGVSLKEVEGTGPRGRITKDDVEAFLXXXXXXXXXXXXXXXXXXXX 235
+ A+P + +A+E+ + L EV G+G GRI K+D+ +L
Sbjct: 170 KTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPP 229
Query: 236 XXXXXTYEDVPISNMRQIIGD--------------RLLQSTQNIPSYIVSSQISVSKLLK 281
+ +S G + + + IP + +I +++L+K
Sbjct: 230 PKPKDMTVPILVSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVK 289
Query: 282 LRQSLNATAKDQ-YKLSINDILIKAIAVAAQRCPDANAYWMPEQGVIRKFKNVDVSVAVA 340
LR+ L A + KLS +KA ++ + P NA I + ++ +A+
Sbjct: 290 LREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMD 349
Query: 341 TPTGLLTPIVKNAESKGLVSISKEIKDLGKRAKDNKLKPEEFQGGTICISNLGMNPAVSM 400
T GL+ P VKN + + I+ E+ L K +L + GGT +SN+G + +
Sbjct: 350 TEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIG-SIGGTF 408
Query: 401 FTSIINPPQSTILAIGTVNKVPVEDAGSEFGFTFDQKMNITGTFDHRTIDGAKGGEFMKE 460
+I PP+ I A+G++ +P + E Q MN++ + DHR IDGA F
Sbjct: 409 AKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKA--QIMNVSWSADHRVIDGATMSRFSNL 466
Query: 461 LKKVIENPLELLL 473
K +ENP +LL
Sbjct: 467 WKSYLENPAFMLL 479
>YGR193c [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 410
Score = 83.2 bits (204), Expect = 8e-16
Identities = 42/114 (36%), Positives = 63/114 (54%)
Query: 1 MSALLSRVAPRMSVLACAARLQLRTYASYPPYTIIGMPALSPTMVQGGLTEWSKNVGDRL 60
M + +S+V+ S + A MPA+SPTM +GG+ W VG+
Sbjct: 1 MLSAISKVSTLKSCTRYLTKCNYHASAKLLAVKTFSMPAMSPTMEKGGIVSWKYKVGEPF 60
Query: 61 EPGDVLAEVETDKAQMDFEFQEEGYLAKILVPAGTKDIPVNKPLAVYVEEESDV 114
GDV+ EVETDK+Q+D E ++G LAKIL G+KD+ V +P+A + + D+
Sbjct: 61 SAGDVILEVETDKSQIDVEALDDGKLAKILKDEGSKDVDVGEPIAYIADVDDDL 114
>SPCC1259.09c [C] KOG0557 Dihydrolipoamide acetyltransferase
Length = 456
Score = 81.3 bits (199), Expect = 3e-15
Identities = 39/78 (50%), Positives = 54/78 (69%), Gaps = 1/78 (1%)
Query: 37 MPALSPTMVQGGLTEWSKNVGDRLEPGDVLAEVETDKAQMDFEFQEEGYLAKILVPAGTK 96
MPALSPTM +G +T+W GD + GD+L EVETDKA MD E Q+ G LAK+L+ G+
Sbjct: 40 MPALSPTMEEGNITKWHFKEGDSFKSGDILLEVETDKATMDVEVQDNGILAKVLIEKGS- 98
Query: 97 DIPVNKPLAVYVEEESDV 114
+IPV K +A+ + E ++
Sbjct: 99 NIPVGKNIAIVADAEDNL 116
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.134 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,628,040
Number of Sequences: 60738
Number of extensions: 869352
Number of successful extensions: 2148
Number of sequences better than 1.0e-05: 26
Number of HSP's better than 0.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2016
Number of HSP's gapped (non-prelim): 60
length of query: 473
length of database: 30,389,216
effective HSP length: 110
effective length of query: 363
effective length of database: 23,708,036
effective search space: 8606017068
effective search space used: 8606017068
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)