ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI1467 good O KOG2042 Posttranslational modification, protein turnover, chaperones Ubiquitin fusion degradation protein-2
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI1467 521254 518384 -957
(957 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL190c [O] KOG2042 Ubiquitin fusion degradation protein-2 1177 0.0
SPAC20H4.10 [O] KOG2042 Ubiquitin fusion degradation protein-2 453 e-127
Hs5174483 [O] KOG2042 Ubiquitin fusion degradation protein-2 297 6e-80
At5g15400 [O] KOG2042 Ubiquitin fusion degradation protein-2 295 2e-79
7297996 [O] KOG2042 Ubiquitin fusion degradation protein-2 290 1e-77
Hs4759288 [O] KOG2042 Ubiquitin fusion degradation protein-2 259 2e-68
7297149 [O] KOG2042 Ubiquitin fusion degradation protein-2 241 4e-63
CE28868 [O] KOG2042 Ubiquitin fusion degradation protein-2 238 3e-62
CE01642 [O] KOG2042 Ubiquitin fusion degradation protein-2 238 3e-62
ECU04g1210 [O] KOG2042 Ubiquitin fusion degradation protein-2 122 3e-27
>YDL190c [O] KOG2042 Ubiquitin fusion degradation protein-2
Length = 961
Score = 1177 bits (3045), Expect = 0.0
Identities = 586/959 (61%), Positives = 741/959 (77%), Gaps = 9/959 (0%)
Query: 1 MTLMRDIFMVTLDPNDSKGCTYVG--DIEDVSDLSADCVDPIVLYQLTENESLQEQPLKY 58
MT + DI +T DP+D++G + + ++ S L D +D ++LYQLTENE L ++P +Y
Sbjct: 1 MTAIEDILQITTDPSDTRGYSLLKSEEVPQGSTLGVDFIDTLLLYQLTENEKL-DKPFEY 59
Query: 59 LNSCFQRCQQSKRISKKNLD-EQQTITLQEIDRLIVGYALVCFQIEEFAIKGSFQQYISD 117
LN CF+R QQ KRI+K + E T QEIDRL++GY +V QIE F + G+F YI+
Sbjct: 60 LNDCFRRNQQQKRITKNKPNAESLHSTFQEIDRLVIGYGVVASQIENFCMNGAFINYITG 119
Query: 118 ILQDLDKFTDLLTAMINRSIQEGTAFDFVDNFFQTVQVYIGKVDATEGFDLNNSTLYNKV 177
I+ +++ +TD L+ +I R+I EGTA D ++ F T+ Y K FDLN S +YN V
Sbjct: 120 IVSNVNSYTDFLSQIIQRAILEGTALDLLNAVFPTLLEYCNK--HVSHFDLNESVIYNNV 177
Query: 178 LTLFELFVSFKPVATIFTKLTGFFADYSTAANQYEKVTLLGPILSLSPLQTAVALKNYVD 237
LT+FELFV+FKP+A IFTK+ GFFADYS +E+ T+LGPILSLSP++ AVA++NY D
Sbjct: 178 LTIFELFVTFKPIAEIFTKIDGFFADYSCKPQDFERKTILGPILSLSPIEAAVAIRNYGD 237
Query: 238 PDSQNQQQINMIHTSLHTEHNVVLQRLFYIVDKIIRASPESRSDLLSYLGQIVNKNHLRR 297
+++QQ MIH SL EH VV+ RLF+IVDK++R S SR+D++SY I NKNHLRR
Sbjct: 238 NLLRSKQQTAMIHESLQAEHKVVIDRLFFIVDKLVRGSLNSRTDMISYFAHIANKNHLRR 297
Query: 298 GDHAQVNKLASNSFMTNITLMLIKFSLPFLDVSYKKIDKIDVNYFNNLNLYIDLNQETRM 357
DH +L+SN FM+NITL+L++FS PFLD+SYKKIDKID NYFNN +L+IDL+ ETR+
Sbjct: 298 ADHPPFKELSSNGFMSNITLLLVRFSQPFLDISYKKIDKIDANYFNNPSLFIDLSGETRL 357
Query: 358 NSDAKEADEFYDQNKKTNEEEPNFISHCFFLTLTYLHYGIGGTILFDERYAPEVTKLKEH 417
NSD KEAD FYD+N+KT + +PNFIS CFFLTLTYLHYG+GGT+ F+E+ E+ LKE
Sbjct: 358 NSDFKEADAFYDKNRKTADSKPNFISDCFFLTLTYLHYGLGGTLSFEEKMGSEIKALKEE 417
Query: 418 LTHLRQVINNSQNSMMARFGEIQLKQLEKRYHHLSSVRSSCQGFFSNKTVHLEVFDFIAG 477
+ ++++ N + + ARF QL ++EK S+R + QGFF+++++ LEVFDFI G
Sbjct: 418 IEKVKKIAAN--HDVFARFITAQLSKMEKALKTTESLRFALQGFFAHRSLQLEVFDFICG 475
Query: 478 ASTFLMRVIDPYHQYPFKTIDLPLIPDQIGVENVDNAEYLRKNAPVPFKYYPEFVIEGSI 537
ASTFL+RV+DP H++PFK I LPLIPDQIGVENVDNA++LR +APVPFKYYPEFV+EG +
Sbjct: 476 ASTFLIRVVDPEHEFPFKQIKLPLIPDQIGVENVDNADFLRAHAPVPFKYYPEFVVEGPV 535
Query: 538 NYCQYVTKYVQNPLFRNPRLHSYIELATMILRCPELISNPHLKGKMVQVLSIGAMPMSDN 597
NY Y++KY +P+FRNPRL S++E TM+LRCPEL+SNPHLKGK+VQ+LS+GAMP++DN
Sbjct: 536 NYSLYISKYQTSPIFRNPRLGSFVEFTTMVLRCPELVSNPHLKGKLVQLLSVGAMPLTDN 595
Query: 598 SPGFMMEIFEHNDIVLKNLLYGLLDFYVIVEKTGSSSQFYDKFNARYSISIILEAL-YEI 656
SPGFMM+IFEH+++V KNLLY LLDFYVIVEKTGSSSQFYDKFN+RYSISIILE L Y+I
Sbjct: 596 SPGFMMDIFEHDELVNKNLLYALLDFYVIVEKTGSSSQFYDKFNSRYSISIILEELYYKI 655
Query: 657 PHYRNQLLWQSQNNSDFFVRFVARMLNDLTFLLDEGLTTLADVHNIQLELENRAKGLPPS 716
P Y+NQL+WQSQNN+DFFVRF ARMLNDLTFLLDEGL+ LA+VHNIQ EL+NRA+G PP+
Sbjct: 656 PSYKNQLIWQSQNNADFFVRFDARMLNDLTFLLDEGLSNLAEVHNIQNELDNRARGAPPT 715
Query: 717 REEETQELQNRLKSAERQAKSSCGLSEKSLVLFNIFTKHIPKAFSTPEIVDRLAAMLDYN 776
REEE +ELQ RL SA RQAKSSCGL++KS+ LF I++K IP AF TPEIV RLA+ML+YN
Sbjct: 716 REEEDKELQTRLASASRQAKSSCGLADKSMKLFEIYSKDIPAAFVTPEIVYRLASMLNYN 775
Query: 777 LESLVGSKCRELKVKDPSKYQFNPKTLLQTLATIYINLADEQEFIAAVARDGRSFNKELF 836
LESLVG KC ELKVKDP Y FNPK LL+ L T+YINL+++ EFI+AVA+D RSFN+ LF
Sbjct: 776 LESLVGPKCGELKVKDPQSYSFNPKDLLKALTTVYINLSEQSEFISAVAKDERSFNRNLF 835
Query: 837 KKAVHILSVKTGLFSEEMCHKLIYFADSAXXXXXXXXXXXXXXXXXXXXFLDPLMYTIMK 896
+AV IL KTGL S E KL+ FA+ A FLDPLMYTIMK
Sbjct: 836 VRAVDILGRKTGLASPEFIEKLLNFANKAEEQRKADEEEDLEYGDVPDEFLDPLMYTIMK 895
Query: 897 DPVILPTSKVTIDRSTIKAHLLSDSTDPFNRSPLKLEEVIPNVELKEKILEFRKSKRSK 955
DPVILP SK+ IDRSTIKAHLLSDSTDPFNR PLKLE+V PN EL++KIL F+K K+ +
Sbjct: 896 DPVILPASKMNIDRSTIKAHLLSDSTDPFNRMPLKLEDVTPNEELRQKILCFKKQKKEE 954
>SPAC20H4.10 [O] KOG2042 Ubiquitin fusion degradation protein-2
Length = 1010
Score = 453 bits (1166), Expect = e-127
Identities = 300/893 (33%), Positives = 453/893 (50%), Gaps = 44/893 (4%)
Query: 67 QQSKRISKKNLDEQQTITLQEIDRLIVGYALVCFQIEEFAIKGSFQQYISDILQDLDKFT 126
Q KR+ K + + L + L+V YA + + + +F D+ + L
Sbjct: 152 QYKKRLPKDENQDFKIHYLSLLKSLLVSYAGIVVMLPD-----TFNSETIDLAEVLIGAE 206
Query: 127 DLLTAMINRSIQEGTAFDFVDNFFQTVQVYIGKVDATEGFDLNNSTLYNKVLTLFELFVS 186
+ ++ +Q + + F ++ K+ +N T+ V+ + VS
Sbjct: 207 GIPLEFLSEFVQRFEHENLDELFIPVLESLSLKIGL-----MNVDTVQMNVMQIILQLVS 261
Query: 187 FKPVATIFTKLTGFFADYSTAANQYEKVTLLGPILSLSPLQTAVALKNYVDPDSQNQQQI 246
KP+A + KL + + + A + E T LG I SLS VA + + + ++ Q I
Sbjct: 262 LKPIALLLPKLPSW--NPTNNAGEIEYKTFLGRISSLSVFTQDVASRYFSNSTERSAQNI 319
Query: 247 NMIHTSLHTEHNVVLQRLFYIVDKIIRASPESRSDLLSYLGQIVNKNHLRRGDHAQVNKL 306
+ +SL + LF I + +IR S R +L + +VN NH R+ +
Sbjct: 320 SSSISSLKLTMSTYQDVLFQIFNTLIRTSTSLRESVLDFFAMVVNANHKRQSIQVNHFDI 379
Query: 307 ASNSFMTNITLMLIKFSLPFLDVSYKKIDKIDVNYFNNLNLYIDLNQETRMNSDAKEADE 366
S++ M N + +L + S PFLD+ KID++ V YF N +D+ +ET++N+D K ++
Sbjct: 380 TSDACMLNFSHVLSRLSEPFLDIGCSKIDRVQVEYFRR-NPRVDIKEETKLNADQKASES 438
Query: 367 FYDQNKKTNEEEPNFISHCFFLTLTYLHYGIGGTILFDERYAPEVT---KLKEHLTHLRQ 423
FY K E NFIS FFL L + HYG+ T E+ + KLKE L +Q
Sbjct: 439 FYS---KPAEGSNNFISDIFFLNLAFHHYGVNATFKALEQLVQSIRDSEKLKERLETEQQ 495
Query: 424 VINNSQNSMMARFGEIQLKQLEKRYHHLSSVRSSCQGFFSNKTVHLEVFDFIAGASTFLM 483
N S A QL +L++R S + + + F F+ + +L
Sbjct: 496 ---NMSGSFQATRLTAQLSRLDQRLDLDRSFVHCYEIMLTQTSDTSRSFSFLNFVAIWLS 552
Query: 484 RVIDPYHQ-YPFKTIDLPLIPDQIGVENVDNAEYLRKNAPVPFKYYPEFVIEGSINYCQY 542
R+ D YP + LP +NAP FK PE+ IE +Y
Sbjct: 553 RLADGQSSTYPKMPLSLPF----------------NENAPEAFKCLPEYFIETITDYMLS 596
Query: 543 VTKYVQNPLFRNPRLHSYIELATMILRCPELISNPHLKGKMVQVLSIGAMPMSDNSPGFM 602
+ K + L + L E L I NP+L+ K+ ++L G S +
Sbjct: 597 LFKTSSSTLTLHS-LEPLCEFCVSFLTQANYIKNPYLRAKLAEILYFGVQTHVGRSE-LL 654
Query: 603 MEIFEHNDIVLKNLLYGLLDFYVIVEKTGSSSQFYDKFNARYSISIILEALYEIPHYRNQ 662
+++ + + + LL L+ FY+ +E TG S+QFYDKFN R+ I + +++ P Y +
Sbjct: 655 LDVVRTSKVATRWLLPALMAFYIEIESTGQSTQFYDKFNIRFYICEVFRTIWKQPAYFGK 714
Query: 663 LLWQSQNNSDFFVRFVARMLNDLTFLLDEGLTTLADVHNIQLELENRAKGLPPSREEETQ 722
L + + N FFV+FVA MLND T+LLDE L L ++HN+Q L + + + Q
Sbjct: 715 LEQEQKTNLPFFVKFVALMLNDATYLLDEALLKLTEIHNLQSLLADAISN--SNSNQNVQ 772
Query: 723 ELQNRLKSAERQAKSSCGLSEKSLVLFNIFTKHIPKAFSTPEIVDRLAAMLDYNLESLVG 782
E Q+ L +AERQA + C L +++ + +FT IPKAF EIVDRLAAML+YNL++L G
Sbjct: 773 ESQSNLAAAERQASTYCQLGNETIFMLKLFTSSIPKAFCAVEIVDRLAAMLNYNLQALCG 832
Query: 783 SKCRELKVKDPSKYQFNPKTLLQTLATIYINLADEQEFIAAVARDGRSFNKELFKKAVHI 842
KC LKV+DP+KY FN KTLL + +Y+NL +E F+ AVA DGRS++KE+F++A I
Sbjct: 833 PKCSNLKVEDPTKYHFNAKTLLSIIFDVYLNLCNEPAFVEAVAHDGRSYSKEIFERATSI 892
Query: 843 LSVKTGLFSEEMCHKLIYFADSAXXXXXXXXXXXXXXXXXXXXFLDPLMYTIMKDPVILP 902
++ K L S + F + FLDPLM+TIMKDPV+LP
Sbjct: 893 MT-KHNLKSSFDIEAIKEFVNRVEAFRLQEATEEEDMGDIPDYFLDPLMFTIMKDPVVLP 951
Query: 903 TSKVTIDRSTIKAHLLSDSTDPFNRSPLKLEEVIPNVELKEKILEFRKSKRSK 955
S ++IDRSTIKAHLLSD+TDPFNR+PL L++V PN L+E+I F KSKR+K
Sbjct: 952 RSGISIDRSTIKAHLLSDATDPFNRTPLTLDDVTPNDTLREEINTFLKSKRNK 1004
>Hs5174483 [O] KOG2042 Ubiquitin fusion degradation protein-2
Length = 1302
Score = 297 bits (760), Expect = 6e-80
Identities = 253/922 (27%), Positives = 425/922 (45%), Gaps = 72/922 (7%)
Query: 56 LKYLNSCFQRCQQSKRISKKNLDEQQTITLQEIDRLIVGYALVCFQIEEFAIKGSFQQYI 115
L YL CF R ++ + K + + +L+ C ++GS Q
Sbjct: 427 LNYLIECFDRVGIEEKKAPKMCSQPA------VSQLLSNIRSQCISHTALVLQGSLTQPR 480
Query: 116 SDILQDLDKFTDLLTAMINRSIQEGTAFDFVDNFFQTVQVYI--------GKVDATEGFD 167
S L + + L+ M+ R++ G + V Q +V+ G A +
Sbjct: 481 S-----LQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECS 535
Query: 168 LNNSTLYNKVLTLFEL----FVSFKPVATIFTKLTGFFADYST--AANQYEKVTLLGPIL 221
L++ ++ L EL F PV + L + + + ++++ LG
Sbjct: 536 LDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFF 595
Query: 222 SLSPL--QTAVALKNYVDPDSQNQQQINMIHTSLHTEHNVVLQRLFYIVDKIIRASPESR 279
S S ++ Y + + ++ SL + Q LF I+ I+ + E+R
Sbjct: 596 SFSVFAEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSIL-LNGETR 654
Query: 280 SDLLSYLGQIVNKNHLRRGDHAQVNKLASNSFMTNITLMLIKFSLPFLDVSYKKIDKIDV 339
LSY+ +VN N + ++++ FM N +L + S K++ +D
Sbjct: 655 EAALSYMAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKI------KLETVDP 708
Query: 340 NYFNNLNLYIDL-NQETRMNSDAKEADEFYDQ--NKKTNEEEPNFISHCFFLTLTYLHYG 396
Y + I L N ETR+N+ ++ +++ + + EP F + CFFLTL H
Sbjct: 709 TYIFHPRCRITLPNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLS 768
Query: 397 IGGTILFDERYAPEVTKLKEHLTHLRQVINNS---QNSMMARFGEIQLKQLEKRYHHLSS 453
I + RY + ++E + + NN ++S +A LK+ + + L
Sbjct: 769 ILPSC---RRYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVR 825
Query: 454 VRSSCQGFFSNKTVHLEVFDFIAGASTFLMRVIDPYHQYPFKTIDLPLIPDQIGVENVDN 513
++ +++ +F L+R++DP YP I LPL D
Sbjct: 826 CKACADAGLLDESFLRRCLNFYGLLIQLLLRILDP--AYP--DITLPLNSD--------- 872
Query: 514 AEYLRKNAPVPFKYYPEFVIEGSINYCQYVTKYVQNPLFRNPRLHSYIELATMILRCPEL 573
P F PEF +E + ++ +Y L+ P + ++L
Sbjct: 873 -------VPKVFAALPEFYVEDVAEFLFFIVQYSPQALYE-PCTQDIVMFLVVMLCNQNY 924
Query: 574 ISNPHLKGKMVQVLSIGAMPMSDNSPGFMMEIFEHNDIVLKNLLYGLLDFYVIVEKTGSS 633
I NP+L K+V+V+ + + + F E+ E++ + K L+ L+ FY VE TG++
Sbjct: 925 IRNPYLVAKLVEVMFMTNPAVQPRTQKFF-EMIENHPLSTKLLVPSLMKFYTDVEHTGAT 983
Query: 634 SQFYDKFNARYSISIILEALYE-IPHYRNQLLWQSQNNSDFFVRFVARMLNDLTFLLDEG 692
S+FYDKF RY IS I ++L++ I H+ + + N+ FVR++ ++ND TFLLDE
Sbjct: 984 SEFYDKFTIRYHISTIFKSLWQNIAHHGTFM--EEFNSGKQFVRYINMLINDTTFLLDES 1041
Query: 693 LTTLADVHNIQLELENRAKGLPPSREEETQELQNRLKSAERQAKSSCGLSEKSLVLFNIF 752
L +L +H +Q E++N+ + R+++ Q Q++L ER ++S L+ +++ +F+I
Sbjct: 1042 LESLKRIHEVQEEMKNKEQWDQLPRDQQ-QARQSQLAQDERVSRSYLALATETVDMFHIL 1100
Query: 753 TKHIPKAFSTPEIVDRLAAMLDYNLESLVGSKCRELKVKDPSKYQFNPKTLLQTLATIYI 812
TK + K F PE+ RLAAML++NL+ L G KCR+LKV++P KY F PK LL L IY+
Sbjct: 1101 TKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIYL 1160
Query: 813 NLADEQEFIAAVARDGRSFNKELFKKAVHILSVKTGLFSEEMCHKLIYFADSAXXXXXXX 872
L D F A+A D RS++KELF++ + + K G+ S K A+
Sbjct: 1161 QL-DCARFAKAIADDQRSYSKELFEEVISKMR-KAGIKSTIAIEKFKLLAEKVEEIVAKN 1218
Query: 873 XXXXXXXXXXXXXFLDPLMYTIMKDPVILPTSKVTIDRSTIKAHLLSDSTDPFNRSPLKL 932
F DPLM T+M DPV LP+ + +DRS I HLL+ TDPFNR L
Sbjct: 1219 ARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTI-MDRSIILRHLLNSPTDPFNRQTLTE 1277
Query: 933 EEVIPNVELKEKILEFRKSKRS 954
+ P ELKE+I + + K++
Sbjct: 1278 SMLEPVPELKEQIQAWMREKQN 1299
>At5g15400 [O] KOG2042 Ubiquitin fusion degradation protein-2
Length = 1038
Score = 295 bits (755), Expect = 2e-79
Identities = 225/799 (28%), Positives = 385/799 (48%), Gaps = 97/799 (12%)
Query: 212 EKVTLLGPILSLSPLQTAVALKNYVDPDSQ-----NQQQINMIHTSLHTEHNV--VLQRL 264
E ++LGP +S L K+ D Q ++++ + +S T N +L
Sbjct: 260 ELTSILGPFFHISALPDNTLFKSQPDVGQQCFSEASERRPADLLSSFSTIKNFMNILYSG 319
Query: 265 FYIVDKIIRASPESRSDLLSYLGQIVNKNHLRRGDHAQVNKL--ASNSFMTNITLMLIKF 322
+ V I+ S ++R +L +L +++N N R H QV+ + AS+ N++ ++++
Sbjct: 320 LHDVLMILLKSTDTRERVLQFLAEVINANASRA--HIQVDPVSCASSGMFVNLSAVMLRL 377
Query: 323 SLPFLDVSYKKIDKIDVNYFNNLNLYIDLNQETRMNSDAKEADEFYDQNKKTNEEEPN-- 380
PFLD K DKID Y + L+ T +++ ++E E+ ++ N +
Sbjct: 378 CEPFLDPHLTKRDKIDPKYAF-CGHRLKLSDLTALHASSEEVTEWIGKDAMANANDAGRE 436
Query: 381 --------------------------------FISHCFFLTLTYLHYGIGGTILFDERYA 408
FI CFF+T L+ G+ + + A
Sbjct: 437 NGNESRLLQSKEATSSSSNASGQNAKSATKYTFICECFFMTARVLNLGLLKALSDFKHLA 496
Query: 409 PEVTKLKEHLTHLRQVINNSQNSMMARFGEIQLKQLEKRYHHLSSVRSSCQGFFSNKTVH 468
++++ +++L L+ + + + + + E+ + ++EK LSS C ++
Sbjct: 497 QDISRGEDNLATLKAMRDQAPSPQL----ELDISRMEKELE-LSSQEKLC-----HEAQI 546
Query: 469 LEVFDFIAGASTFLMRVIDPYHQYPFKTIDLPLIPDQIGVENVDNAEYLRKNAPVPFKYY 528
L DFI A +F ++ + +G + L P+ F
Sbjct: 547 LRDGDFIQRALSFYRLMV-------------VWLVGLVGGFKMP----LPSTCPMEFSCM 589
Query: 529 PEFVIEGSINYCQYVTKYVQNPLFRNPRLHSYIELATMILRCPELISNPHLKGKMVQVLS 588
PE +E ++ + ++ + L P L ++ M + PE + NP+L+ KMV+VL+
Sbjct: 590 PEHFVEDAMELLIFASR-IPKALDGVP-LDDFMNFIIMFMASPEYVRNPYLRAKMVEVLN 647
Query: 589 IGAMPMSDNSPGFMMEIFEHNDIVLKNLLYGLLDFYVIVEKTGSSSQFYDKFNARYSISI 648
MP S +S +FE + + L+ L+ LL YV +E TGS +QFYDKFN R++I+
Sbjct: 648 CW-MPRSSSSSSATSTLFEGHQLSLEYLVRNLLKLYVDIEFTGSHTQFYDKFNIRHNIAE 706
Query: 649 ILEALYEIPHYRNQLLWQ---SQNNSDFFVRFVARMLNDLTFLLDEGLTTLADVHNIQLE 705
+LE L+++P +RN W+ ++ F+ ++ND +LLDE L + ++ I+ +
Sbjct: 707 LLEYLWQVPSHRNA--WRRIAKDEEKGVYLNFLNFLVNDSIYLLDESLNKILEIKQIEAD 764
Query: 706 LENRAKGLPPSREEETQELQNRLK---SAERQAKSSCGLSEKSLVLFNIFTKHIPKAFST 762
+ N A+ + TQE Q R + S E + L+ + + + ++ I F
Sbjct: 765 MSNTAEW----EQRPTQERQERTRLFHSQENIVRIDMKLANEDVTMLAFTSEEITAPFLL 820
Query: 763 PEIVDRLAAMLDYNLESLVGSKCRELKVKDPSKYQFNPKTLLQTLATIYINLADEQE--- 819
PE+V+R+A ML+Y L LVG + + L +KDP KY+F PK LL+ + IY+NLA
Sbjct: 821 PEMVERVANMLNYFLLQLVGPQRKSLSLKDPEKYEFRPKQLLKQIVRIYVNLARGDTVNI 880
Query: 820 FIAAVARDGRSFNKELFKKAVHILSVKTGLFSEE--MCHKLIYFADSAXXXXXXXXXXXX 877
F A++ DGRS+N++LF +L EE + + + A
Sbjct: 881 FPGAISSDGRSYNEQLFNAGADVLR----RIGEEGRIIQEFMELGTKAKAAASEALDAEA 936
Query: 878 XXXXXXXXFLDPLMYTIMKDPVILPTSKVTIDRSTIKAHLLSDSTDPFNRSPLKLEEVIP 937
FLDP+ YT+M+DPVILP+S++T+DR I+ HLLSD+ DPFNR+ L + +IP
Sbjct: 937 ALGEIPDEFLDPIQYTLMRDPVILPSSRITVDRPIIQRHLLSDNHDPFNRAHLTSDMLIP 996
Query: 938 NVELKEKILEFRKSKRSKK 956
++ELK KI EF KS +SKK
Sbjct: 997 DIELKAKIDEFVKSHQSKK 1015
>7297996 [O] KOG2042 Ubiquitin fusion degradation protein-2
Length = 1217
Score = 290 bits (741), Expect = 1e-77
Identities = 250/939 (26%), Positives = 442/939 (46%), Gaps = 63/939 (6%)
Query: 30 SDLSADCVDPIVLYQLTENESLQEQPLKYLNSCFQRCQQSKRISKKNLDEQQTITL--QE 87
S+ + CV P VL + + + L YL C+Q Q S+K Q + L ++
Sbjct: 327 SEAAGTCVAPPVLSIVA---TTKHHVLLYLIRCYQNYQTE--CSRKTPLTQPALQLAFEQ 381
Query: 88 IDRLIVGYALVCFQIEEFAIKGSFQQYISDILQDLDKFTDLLTAMINRSIQEGTAFDFVD 147
+ R+ V ++ +I + Q + D++ L +I + Q+ AFD +
Sbjct: 382 VMRMTV--LVLTDRIYQNLNGHMDQSALLDLMYMAKVSEPFLIDLIAHTHQDREAFDTIF 439
Query: 148 NFFQTVQVYIGKVDATEGFDLNNSTLYNKVLTLFELFV----SFKPVATIFTKLTGFFAD 203
+ QV G + + ++ L +L V S +P+A + ++ F
Sbjct: 440 S-----QVLRGLFAGMQRNICTSKISVQQIEWLSKLVVIKVGSVRPIADLVSRQPNFLPP 494
Query: 204 YSTAANQYE--KVTLLGPILSLSPL-QTAVALKNYVDPDSQNQQQINMIHTSLHTEHNVV 260
T + E K + LGP LS+S + + + + + + LH+
Sbjct: 495 ICTKISGREIVKCSFLGPFLSVSLFAEENIKFAEFTTKNKLEDASSSRLRWELHS----- 549
Query: 261 LQRLFYIVDKIIRASPESRSDLLSYLGQIVNKNHLRRGDHAQVNKLASNSFMTNITLMLI 320
++ ++V + + SR L Y+ I+ N R + LA + FM N+ +L
Sbjct: 550 MRTNMHVVFHSLCVNASSRPKTLEYIASILRHNDRRVQFASDEKLLARDGFMINLMSVLQ 609
Query: 321 KFSLPFLDVSYKKIDKIDVNYFNNLNLYIDLNQETRMNSDAKEADEFYDQNKKTNEEEPN 380
+ S+ K+D+I+ N+ N +++ Q+T++ +E F ++ E N
Sbjct: 610 QLSVKI------KLDRIEPNFHYYKNSLVNIEQDTKIRYSEEEYRNFLARDFSQPVENTN 663
Query: 381 FISHCFFLTLTYLHYGIGGTILFDERYAPEVTKLKEH---LTHLRQVINNSQNSMMARFG 437
F + C+FLTL H G I +RY +V +KE + L + ++ NS A
Sbjct: 664 FQTQCWFLTLQAHHLGYLPAI---QRYRQKVRAIKELQKLIDELDRTKSHWMNSRYANRN 720
Query: 438 EIQLKQLEKRYHHLSSVRSSCQGFFSNKTVHLEVFDFIAGASTFLMRVIDPYHQYPFKTI 497
++ EK+ L+ ++ C+ + + +F + F++ +Q+ + I
Sbjct: 721 NQFKERWEKQLRKLNRSKTCCEITLLDPGLLQRCTEFYSTVCEFML------YQFEGRPI 774
Query: 498 DLPLIPDQIGVENVDNAEYLRKNAPVPFKYYPEFVIEGSINYCQYVTKYVQNPLFRNPRL 557
+ P I + + L +A F PE+ I+ + + ++ N R
Sbjct: 775 EGPFI------SKLPVQQLLPTDA---FSALPEWYIDDIAEFILFTMQHA-NMDIRQGID 824
Query: 558 HSYIELATMILRCPELISNPHLKGKMVQVLSIGAMPMSDNSPGFMMEIFEHNDIVLKNLL 617
HS I + LI NP++ K+V+V+ + ++ +++ M ++++ L+
Sbjct: 825 HSIITWLLTCVCASHLIKNPYVTAKLVEVMFVFSLKPANSVNAAMW----NHELAQNALV 880
Query: 618 YGLLDFYVIVEKTGSSSQFYDKFNARYSISIILEALYEIPHYRNQLLWQSQNNSDFFVRF 677
L+ FYV VE TG S++FYDKF RY IS + ++++E P +R ++ +S+ + F V+F
Sbjct: 881 SSLMRFYVDVETTGQSTEFYDKFTIRYHISHLFKSMWENPIHRQAVICESRVGNQF-VKF 939
Query: 678 VARMLNDLTFLLDEGLTTLADVHNIQLELENRAKGLPPSREEETQELQNRLKSAERQAKS 737
V ++ND TFLLDE L L +H Q L ++A S E++ L +L + ERQ +S
Sbjct: 940 VNMLMNDTTFLLDECLENLKRIHQTQQLLSDKANLSKMSAEQQQSRL-TQLATDERQCRS 998
Query: 738 SCGLSEKSLVLFNIFTKHIPKAFSTPEIVDRLAAMLDYNLESLVGSKCRELKVKDPSKYQ 797
L+ +++ LF+ T I + F E+VDRL++ML++NL+ L G KC +LKVK+P+KY
Sbjct: 999 YLTLARETVDLFHYLTSDIKEPFMRDELVDRLSSMLNFNLKQLAGPKCNDLKVKNPAKYG 1058
Query: 798 FNPKTLLQTLATIYINLADEQEFIAAVARDGRSFNKELFKKAVHILSVKTGLFSEEMCHK 857
+ P++LL + IY++L D F A+A D RSF+ ++ +A + + L S +
Sbjct: 1059 WEPRSLLAQIFDIYLHL-DCDRFAEALAADERSFDVQICNEAASRIK-RLALRSAVEVER 1116
Query: 858 LIYFADSAXXXXXXXXXXXXXXXXXXXXFLDPLMYTIMKDPVILPTSKVTIDRSTIKAHL 917
A F DPLM T+M DPV+LP+ V +DR+ I HL
Sbjct: 1117 FKALTQRAHEIYVTNLQTEDECADAPDEFKDPLMDTLMSDPVVLPSGTV-MDRAIITRHL 1175
Query: 918 LSDSTDPFNRSPLKLEEVIPNVELKEKILEFRKSKRSKK 956
L+ TDPFNR PL + ++ N+ELK++I +RK +R K+
Sbjct: 1176 LNSCTDPFNRQPLTEDMLVANIELKQRIDAWRKEQRGKR 1214
>Hs4759288 [O] KOG2042 Ubiquitin fusion degradation protein-2
Length = 1073
Score = 259 bits (661), Expect = 2e-68
Identities = 247/953 (25%), Positives = 423/953 (43%), Gaps = 111/953 (11%)
Query: 58 YLNSCFQRCQQSKR----------ISKKNLDEQQT----ITLQEIDRLIVGYALVCFQIE 103
YL SCFQR ++ + +NL T +TL+ + LV +E
Sbjct: 176 YLYSCFQRAKEEITKVPENLLPFAVQCRNLTVSNTRTVLLTLEIYVDQNIHEQLVDLMLE 235
Query: 104 EFAIKGSFQQYISDILQDLDKFTDLLTAMINRSIQEGTAFDFVDNFFQTVQVYIGKVDAT 163
AI+G+ ++Y++ I + T+ L +I I + F + + +G++
Sbjct: 236 --AIQGA-REYMNKIY--FEDVTEFLEEVIEALILDEEVRTFPEVMIPVFDILLGRI--- 287
Query: 164 EGFDLNNSTLYNKVLTLFELFVSFKPVATIFTKLTGFFADYSTAANQYEKVTLLGPILSL 223
+ +L LY L + F K +A +F + + Q + TLLG ILS+
Sbjct: 288 KDLELCQILLY-AYLDILLYFTRQKDMAKVFVE---YIQPKDPTNGQMYQKTLLGVILSI 343
Query: 224 SPL-QTAVALKN---YVDPDSQNQQQINMIHTSLHTEHNVVLQRLFYIVDKIIRASPESR 279
S L +T ++N +++P + Q+I + ++H ++++ ++ +++ SPE++
Sbjct: 344 SCLLKTPGVVENHGYFLNPSRSSPQEIKVQEANIHQFMAQFHEKIYQMLKNLLQLSPETK 403
Query: 280 SDLLSYLGQIVNKNHLRRGDHAQ------VNKLASNSFMTNITLMLIKFSLPFLDVSYKK 333
+LS+LG ++ N R A AS++F N+ L+K PF +
Sbjct: 404 HCILSWLGNCLHANAGRTKIWANQMPEIFFQMYASDAFFLNLGAALLKLCQPFCKPRSSR 463
Query: 334 IDKIDVNYFNNLNLYIDLNQETR------MNSDAKEADEFYDQNKKTNEEEPNFISHCFF 387
+ + Y +LN E R M KE + + N ++
Sbjct: 464 LLTFNPTYC----ALKELNDEERKIKNVHMRGLDKETCLIPAVQEPKFPQNYNLVTENLA 519
Query: 388 LTLTYLHYGIGGTILFDERYAPEVTKLKEHLTHLRQVINNSQNSMMARFGEIQLKQLEKR 447
LT L+ G R ++ K+ ++L L+ ++Q S L ++
Sbjct: 520 LTEYTLYLGF-------HRLHDQMVKINQNLHRLQVAWRDAQQSSSPA-----ADNLREQ 567
Query: 448 YHHLSSVRSSCQGFFSNKTVHLEVFDFIAGASTFLMRVIDPYHQYPFKTIDLPLIPDQIG 507
+ L ++ + S KT E L ++ + + ++ Q+
Sbjct: 568 FERLMTI------YLSTKTAMTE--------PQMLQNCLN-------LQVSMAVLLVQLA 606
Query: 508 VENVDNAEYLRKNAPVP-----FKYYPEFVIEGSINYCQYVTKYVQNPLFRNP-RLHSYI 561
+ N + ++ + P+P Y PEF + ++ ++ ++ + L + L +
Sbjct: 607 IGN-EGSQPIELTFPLPDGYSSLAYVPEFFADNLGDFLIFLRRFADDILETSADSLEHVL 665
Query: 562 ELATMILRCPELISNPHLKGKMVQVLSIGAMPMSDNSPGFMMEIFEHNDIVLKNLLYG-- 619
T+ E + NPHL+ K+ +VL MP D +P ++ H V N Y
Sbjct: 666 HFITIFTGSIERMKNPHLRAKLAEVLE-AVMPHLDQTPNPLVSSVFHRKRVFCNFQYAPQ 724
Query: 620 ----LLDFYVIVEKTGSSSQFYDKFNARYSISIILEALYEIPHYRNQLL----WQSQN-- 669
L+ +V +E TG QF KFN R + IL ++ YR + + S+N
Sbjct: 725 LAEALIKVFVDIEFTGDPHQFEQKFNYRRPMYPILRYMWGTDTYRESIKDLADYASKNLE 784
Query: 670 --NSDFFVRFVARMLNDLTFLLDEGLTTLADVHNIQLELENRA-KGLPPSREEETQELQN 726
N F+RF+ ++ND FLLDE + L+ + Q+E + L P E +E +
Sbjct: 785 AMNPPLFLRFLNLLMNDAIFLLDEAIQYLSKIKIQQIEKDRGEWDSLTP---EARREKEA 841
Query: 727 RLKSAERQAKSSCGLSEKSLVLFNIFTKHIPKAFSTPEIVDRLAAMLDYNLESLVGSKCR 786
L+ + A+ +S +++ T I F P + +R+ +ML+Y L+ LVG K
Sbjct: 842 GLQMFGQLARFHNIMSNETIGTLAFLTSEIKSLFVHPFLAERIISMLNYFLQHLVGPKMG 901
Query: 787 ELKVKDPSKYQFNPKTLLQTLATIYINLADEQEFIAAVARDGRSFNKELFKKAVHILSV- 845
LKVKD S++ F P+ L+ + TIY+NL DE+ F A V +DGRS++ LF + V +L
Sbjct: 902 ALKVKDFSEFDFKPQQLVSDICTIYLNLGDEENFCATVPKDGRSYSPTLFAQTVRVLKKI 961
Query: 846 -KTGLFSEEMCHKLIYFADSAXXXXXXXXXXXXXXXXXXXXFLDPLMYTIMKDPVILPTS 904
K G M A+ FLDP+M T+M DPV+LP+S
Sbjct: 962 NKPG----NMIMAFSNLAERIKSLADLQQQEEETYADACDEFLDPIMSTLMCDPVVLPSS 1017
Query: 905 KVTIDRSTIKAHLLSDSTDPFNRSPLKLEEVIPNVELKEKILEFRKSKRSKKE 957
+VT+DRSTI HLLSD TDPFNRSPL ++++ PN ELKEKI + ++ +KE
Sbjct: 1018 RVTVDRSTIARHLLSDQTDPFNRSPLTMDQIRPNTELKEKIQRWLAERKQQKE 1070
>7297149 [O] KOG2042 Ubiquitin fusion degradation protein-2
Length = 972
Score = 241 bits (615), Expect = 4e-63
Identities = 234/944 (24%), Positives = 416/944 (43%), Gaps = 106/944 (11%)
Query: 50 SLQEQPLKYLNSCFQRCQQSKRISKKNLDEQQTITLQEIDRLIVGYALVCF-QIEEFAIK 108
+++ + ++YL F RC + ++ I +I LI+ A C Q + FA +
Sbjct: 88 AMERRAMRYLKGAFTRCGL--------IQAERKIDCSKILALILNNASTCMRQPDLFAPQ 139
Query: 109 GSFQQYISDILQDLDK-------FTDLLTAMINRSIQEGTAFDFVDNFFQTVQVYIGKVD 161
Q++ QD D+ F +T + ++ A + F V + K
Sbjct: 140 SFGAQWMEMFEQDEDEHDTSTQEFLIRVTCKVMEEVEPIEALGALKAIFYPVLTELQKNI 199
Query: 162 ATEGFDLNNSTLYNKVLTLFELFVSFKPVATIFTKLTGFFADYSTAANQYEKVTLLGPIL 221
A LN T+ + FV K A + L + A+ TLLG +L
Sbjct: 200 AK----LNLITMKKNTFWILGYFVRDKRAAVLGELLIDYTTPNPRASGSEYMDTLLGSLL 255
Query: 222 SLSPL-QTAVALKNYVDPDSQNQQQINMIHTSLHTEHNVVLQRLFYIVDKIIRASPESRS 280
+S L +T + S NQ + H + Q +F +V +++ SPE++
Sbjct: 256 CISILPKTQTGKYEFFQELSINQTDEALWALLSHHQ-----QSIFLLVKQLLVLSPETKK 310
Query: 281 DLLSYLGQIVNKN----HLRRGDHAQVNKLA----SNSFMTNITLMLIKFSLPFLDVSYK 332
L ++G ++ N HL +A + + A S++FMTN+T +L++ P S K
Sbjct: 311 KTLQWVGNCLDANVPRGHLWSSINASLEQTAHSTSSDAFMTNLTAVLVRLCAPLCMPSLK 370
Query: 333 KIDKIDVNYFNNLNLYIDLNQETRMNSDAKEADEFYDQNK-KTNEEEPNFISHCFFLTLT 391
+ +D Y N + + + A+ ++ + + E+ NF
Sbjct: 371 VL-LVDPTYCAVPNKDRQAKGVSMLRAHAETCLLTSEEGEERLTAEKYNF---------- 419
Query: 392 YLHYGIGGTILFDERYAPEVTKLKEHLTHLRQVINNSQNSMMARFGEIQLKQLEKRYHHL 451
R+ + +L+ +++N+ NS +A+ + + + +
Sbjct: 420 --------------RFVRVLRELQNTQMAYGEIVNSDPNSEVAKN---LFRMIRDQIQQV 462
Query: 452 SSVRSSCQGFFSNKTVHLEVFDFIAGASTFLMRVIDPYHQYPFKTIDLPLIPDQIGVENV 511
+++++ + T + + F ++ +L + P + + L +
Sbjct: 463 LTIKNT----LAEPTNDMYLLKFFEASAIWLTEIA----MLPREIYEQCLDKRDFSPQVF 514
Query: 512 DNAEYLRKNAPVPFKYY---PEFVIEG---------SINYCQYVTKYVQNPLFRNPRLHS 559
N E L P Y PE +I+ +N QY+ Y +
Sbjct: 515 RNMELLSDTPPFVAPYMQSVPESIIDNISAFLNAARKLNGEQYINIYFSAH-------DA 567
Query: 560 YIELATMILRCPELISNPHLKGKMVQVLS--IGAMPMSDNSPGFMMEIFEHNDIVLKNLL 617
+ ++ + + L+ NPHL+ K+ + L + + M + F+ +F+++ LK ++
Sbjct: 568 FFKMIILFMGSSALVKNPHLRAKLAEALEFLLPSRIMGSHRKTFVSHVFDNHPDRLK-VV 626
Query: 618 YGLLDFYVIVEKTGSSSQFYDKFNARYSISIILEALYEIPHYRN---QLLWQSQNNSD-- 672
LL+ +V +E TG S QF KFN R + I+E L+ P + L +++ N D
Sbjct: 627 RSLLNVFVSIEMTGQSVQFEQKFNYRRPMYAIMEFLWTKPEHVQCFRDLAVEAEQNMDAI 686
Query: 673 ---FFVRFVARMLNDLTFLLDEGLTTLADVHNIQLELENRAKGLPPSREEETQELQNRLK 729
F+RF+ ++ND FLLDE L+ L + +Q +N P E E Q + N L+
Sbjct: 687 EPPIFLRFINLLINDAIFLLDESLSNLEQIKQLQQAQDNGEWESLPHTERE-QHMTN-LQ 744
Query: 730 SAERQAKSSCGLSEKSLVLFNIFTKHIPKAFSTPEIVDRLAAMLDYNLESLVGSKCRELK 789
A+ + ++ L + T I F +VDR+AAML+Y L +LVG K K
Sbjct: 745 HLGMLARFDNIIGRDTINLLKLLTSKIKSIFCHNSMVDRMAAMLNYFLLNLVGPKKERFK 804
Query: 790 VKDPSKYQFNPKTLLQTLATIYINLADEQEFIAAVARDGRSFNKELFKKAVHILSVKTGL 849
VKD +++F+P + ++ IYINL+ ++ F AV++DGRS++++LF A +IL ++ G
Sbjct: 805 VKDKKEFEFDPAQTVIEISHIYINLSSDESFCLAVSQDGRSYSEQLFSYAENIL-IRIG- 862
Query: 850 FSEEMCHKLIYFADSAXXXXXXXXXXXXXXXXXXXXFLDPLMYTIMKDPVILPTSKVTID 909
++ + FA +LDP++ T+M DPV+LP+SKVT+D
Sbjct: 863 -GGQLIGDMSEFAVKVARMGAQYKEEQELLADAPEEYLDPIISTLMTDPVVLPSSKVTVD 921
Query: 910 RSTIKAHLLSDSTDPFNRSPLKLEEVIPNVELKEKILEFRKSKR 953
RSTI HLLSD TDPFNR PL +++V N LK++I + + KR
Sbjct: 922 RSTIARHLLSDQTDPFNREPLTMDKVKSNEALKQEIESWIQGKR 965
>CE28868 [O] KOG2042 Ubiquitin fusion degradation protein-2
Length = 984
Score = 238 bits (608), Expect = 3e-62
Identities = 210/821 (25%), Positives = 366/821 (44%), Gaps = 88/821 (10%)
Query: 166 FDLNNSTLYNKVLTLFELFVSFK-------PVATIFTKLTGFFADYSTA--ANQYEKVTL 216
F+ N + ++L + L +S + P++ + F S ++ ++
Sbjct: 223 FEDNKDEIVRQILRVMNLLLSIRLPSNGPRPLSNLLVNREDFLPTPSEKIQGREFGLMSF 282
Query: 217 LGPILSLSPLQTAVALKNYVDPDSQNQQQINMIHTSLHTEHNVVLQRLFYIVDKI----- 271
LGP S +A + V D + + S++TE + QR+ I +
Sbjct: 283 LGPFFSYGLESSARRPNHRVFVDCE--EDARKYDGSVNTEQKLYFQRMDPIRTMLHQLML 340
Query: 272 -IRASPESRSDLLSYLGQIVNKNHLRRGDHAQVNKLASNSFMTNITLMLIKFSLPFLDVS 330
+ + SR+ L ++ I++ N +R H + + + +MTN ++ FS
Sbjct: 341 PLASDQGSRNKTLRWIATIISTNDIRTRSHYDPSDVLCDHYMTNFLSVMYMFS------- 393
Query: 331 YKKID--KIDVNYFNNLNLYIDLNQETRMNSDAKEADEFYDQNKKTNEEEPNFISHCFFL 388
+KID KI V+Y + I++++ETR+ D A F Q +E +F + CFFL
Sbjct: 394 -EKIDLSKIIVDYPFLPSSLINISKETRLKMDESGAVAFASQFAD-RPDEYHFSTVCFFL 451
Query: 389 TLTYLHYGIGGTILFDERYAPEVTKLKEHLTHLRQVINNSQNSMMARFGEIQLKQLEKRY 448
T+ I + Y+ + +LK + L++ +N A E++ K +
Sbjct: 452 TIAAQRLVIPPLMNQISEYSRHLKELKHKINALKEKLNTVSGFERA---EVEKKLNYETE 508
Query: 449 H------HLSSVRSSCQGFFSNKTVHLEVFDFIAGASTFLMRVIDPYHQYPFKTIDLPLI 502
H HL V++ Q + + DF+ F++ ++
Sbjct: 509 HWKLMSRHLLCVKTQAQ----DPALMASSMDFVDKQMKFILNLL---------------- 548
Query: 503 PDQIGVENVDNAEYLRKNAPVP------FKYYPEFVIEGSINYCQYVTKYVQNPLFRNPR 556
DN + L ++ +P F PE+ +E ++++ Y+ R
Sbjct: 549 --------CDNLDLLGDDSQLPTEVSQMFCALPEYFLEDALDF--YIFAISNGMKLLMER 598
Query: 557 LHSYIELATMILRCPELISNPHLKGKMVQVLSIGAMPMSDNSPGFMMEIFEHNDIVLKNL 616
+I T++ I +P L K+V+VLS P+ N M +NL
Sbjct: 599 NADWISRLTVLFTQYHYIKSPFLVSKLVRVLSSIQPPLWFNVVRLRM--------AQENL 650
Query: 617 LYGLLDFYVIVEKTGSSSQFYDKFNARYSISIILEALYEIPHYRNQLLWQSQNNSDFFVR 676
L ++ FY E G FY+KFN R +I +LE + E Y+ + + ++ F+R
Sbjct: 651 LMCMIKFYSDFEDNGD---FYEKFNVRGNIQYMLEKMEEDMFYKGKFMDMARECGAEFIR 707
Query: 677 FVARMLNDLTFLLDEGLTTLADVHNIQLELENRAKGLPPSREEETQELQNRLKSAERQAK 736
FV ++ND T+ +DE L+ L +H+++ ++ N+ + +E Q+L + A+R+ K
Sbjct: 708 FVNMVINDATWCIDESLSGLKSIHDVEKKMANKVEWDNTDQEIRNQDL-GVYEEAKRKVK 766
Query: 737 SSCGLSEKSLVLFNIFTKHIPKAFSTPEIVDRLAAMLDYNLESLVGSKCRELKVKDPSKY 796
G ++ +L L T + P+ F TP + +RLAAML++NL L+GSK ELKVKDP Y
Sbjct: 767 GWLGTAKSNLKLLLSITVNSPEPFRTPVLGERLAAMLNHNLSQLIGSKASELKVKDPRSY 826
Query: 797 QFNPKTLLQTLATIYINLADEQEFIAAVARDGRSFNKELFKKAVHILSVKTGLFSEEMCH 856
+ P+ + L +IY+ L + F+ +A D R+++ E F A+ + K +
Sbjct: 827 GWEPREFVSLLISIYLKL-NMPAFVKYIAYDERTYSPEFFHNAIECMR-KNSIVGFSQLE 884
Query: 857 KLIYFADSAXXXXXXXXXXXXXXXXXXXXFLDPLMYTIMKDPVILPTSKVTIDRSTIKAH 916
+ A+ F DP+M IM DPV LP+ V +DR+ I+ H
Sbjct: 885 SFEHLAEDVKKEYEAKAELEEEYDDVPEEFKDPIMDAIMVDPVKLPSGHV-MDRAVIERH 943
Query: 917 LLSDSTDPFNRSPLKLEEVIPNVELKEKILEFRKSKRSKKE 957
LLS +PFNR+PL E+ P+ ELK KI E+ KR+ K+
Sbjct: 944 LLSTPNNPFNRAPLSHNELSPDSELKAKIQEWICQKRNSKK 984
>CE01642 [O] KOG2042 Ubiquitin fusion degradation protein-2
Length = 980
Score = 238 bits (608), Expect = 3e-62
Identities = 210/821 (25%), Positives = 366/821 (44%), Gaps = 88/821 (10%)
Query: 166 FDLNNSTLYNKVLTLFELFVSFK-------PVATIFTKLTGFFADYSTA--ANQYEKVTL 216
F+ N + ++L + L +S + P++ + F S ++ ++
Sbjct: 219 FEDNKDEIVRQILRVMNLLLSIRLPSNGPRPLSNLLVNREDFLPTPSEKIQGREFGLMSF 278
Query: 217 LGPILSLSPLQTAVALKNYVDPDSQNQQQINMIHTSLHTEHNVVLQRLFYIVDKI----- 271
LGP S +A + V D + + S++TE + QR+ I +
Sbjct: 279 LGPFFSYGLESSARRPNHRVFVDCE--EDARKYDGSVNTEQKLYFQRMDPIRTMLHQLML 336
Query: 272 -IRASPESRSDLLSYLGQIVNKNHLRRGDHAQVNKLASNSFMTNITLMLIKFSLPFLDVS 330
+ + SR+ L ++ I++ N +R H + + + +MTN ++ FS
Sbjct: 337 PLASDQGSRNKTLRWIATIISTNDIRTRSHYDPSDVLCDHYMTNFLSVMYMFS------- 389
Query: 331 YKKID--KIDVNYFNNLNLYIDLNQETRMNSDAKEADEFYDQNKKTNEEEPNFISHCFFL 388
+KID KI V+Y + I++++ETR+ D A F Q +E +F + CFFL
Sbjct: 390 -EKIDLSKIIVDYPFLPSSLINISKETRLKMDESGAVAFASQFAD-RPDEYHFSTVCFFL 447
Query: 389 TLTYLHYGIGGTILFDERYAPEVTKLKEHLTHLRQVINNSQNSMMARFGEIQLKQLEKRY 448
T+ I + Y+ + +LK + L++ +N A E++ K +
Sbjct: 448 TIAAQRLVIPPLMNQISEYSRHLKELKHKINALKEKLNTVSGFERA---EVEKKLNYETE 504
Query: 449 H------HLSSVRSSCQGFFSNKTVHLEVFDFIAGASTFLMRVIDPYHQYPFKTIDLPLI 502
H HL V++ Q + + DF+ F++ ++
Sbjct: 505 HWKLMSRHLLCVKTQAQ----DPALMASSMDFVDKQMKFILNLL---------------- 544
Query: 503 PDQIGVENVDNAEYLRKNAPVP------FKYYPEFVIEGSINYCQYVTKYVQNPLFRNPR 556
DN + L ++ +P F PE+ +E ++++ Y+ R
Sbjct: 545 --------CDNLDLLGDDSQLPTEVSQMFCALPEYFLEDALDF--YIFAISNGMKLLMER 594
Query: 557 LHSYIELATMILRCPELISNPHLKGKMVQVLSIGAMPMSDNSPGFMMEIFEHNDIVLKNL 616
+I T++ I +P L K+V+VLS P+ N M +NL
Sbjct: 595 NADWISRLTVLFTQYHYIKSPFLVSKLVRVLSSIQPPLWFNVVRLRM--------AQENL 646
Query: 617 LYGLLDFYVIVEKTGSSSQFYDKFNARYSISIILEALYEIPHYRNQLLWQSQNNSDFFVR 676
L ++ FY E G FY+KFN R +I +LE + E Y+ + + ++ F+R
Sbjct: 647 LMCMIKFYSDFEDNGD---FYEKFNVRGNIQYMLEKMEEDMFYKGKFMDMARECGAEFIR 703
Query: 677 FVARMLNDLTFLLDEGLTTLADVHNIQLELENRAKGLPPSREEETQELQNRLKSAERQAK 736
FV ++ND T+ +DE L+ L +H+++ ++ N+ + +E Q+L + A+R+ K
Sbjct: 704 FVNMVINDATWCIDESLSGLKSIHDVEKKMANKVEWDNTDQEIRNQDL-GVYEEAKRKVK 762
Query: 737 SSCGLSEKSLVLFNIFTKHIPKAFSTPEIVDRLAAMLDYNLESLVGSKCRELKVKDPSKY 796
G ++ +L L T + P+ F TP + +RLAAML++NL L+GSK ELKVKDP Y
Sbjct: 763 GWLGTAKSNLKLLLSITVNSPEPFRTPVLGERLAAMLNHNLSQLIGSKASELKVKDPRSY 822
Query: 797 QFNPKTLLQTLATIYINLADEQEFIAAVARDGRSFNKELFKKAVHILSVKTGLFSEEMCH 856
+ P+ + L +IY+ L + F+ +A D R+++ E F A+ + K +
Sbjct: 823 GWEPREFVSLLISIYLKL-NMPAFVKYIAYDERTYSPEFFHNAIECMR-KNSIVGFSQLE 880
Query: 857 KLIYFADSAXXXXXXXXXXXXXXXXXXXXFLDPLMYTIMKDPVILPTSKVTIDRSTIKAH 916
+ A+ F DP+M IM DPV LP+ V +DR+ I+ H
Sbjct: 881 SFEHLAEDVKKEYEAKAELEEEYDDVPEEFKDPIMDAIMVDPVKLPSGHV-MDRAVIERH 939
Query: 917 LLSDSTDPFNRSPLKLEEVIPNVELKEKILEFRKSKRSKKE 957
LLS +PFNR+PL E+ P+ ELK KI E+ KR+ K+
Sbjct: 940 LLSTPNNPFNRAPLSHNELSPDSELKAKIQEWICQKRNSKK 980
>ECU04g1210 [O] KOG2042 Ubiquitin fusion degradation protein-2
Length = 809
Score = 122 bits (305), Expect = 3e-27
Identities = 82/284 (28%), Positives = 140/284 (48%), Gaps = 21/284 (7%)
Query: 675 VRFVARMLNDLTFLLDEGLTTLADVHNIQLELENRAKGLPPSREEETQE-----LQNRLK 729
+ F+ M+ D + L EGL+++ D+ +E ++ L +++E +E + R+
Sbjct: 521 ITFINCMMKDFEYSLSEGLSSIKDIKEDMKVVEELSRELDEAKKERVEEKKIESISERIG 580
Query: 730 SAERQAKSSCGLSEKSLVL----FNIFTKHI----PKAFSTPEIVDRLAAMLDYNLESLV 781
S + + S + S + F++FT HI P F E++ +L+ NL+ +
Sbjct: 581 SLRKSIRFSKNKARNSFLYVDGCFDLFT-HILDEKPDLFLVDEMISNFVRVLNCNLKIIT 639
Query: 782 GSKCRELKVKDPSKYQFNPKTLLQTLATIYINLADEQEFIAAVARDGRSFNKELFKKAVH 841
G KC +L +K P +Y F+ K LL+ + +YI + + F+ VA D F+ + F+ A+
Sbjct: 640 GPKCTDLVIKSPEQYGFDAKNLLRRMVMVYIRIRSSK-FVEMVASDKMYFDIDFFRTALR 698
Query: 842 ILSVKTGLFSEEMCHKLIYFADSAXXXXXXXXXXXXXXXXXXXXFLDPLMYTIMKDPVIL 901
I K L +E +L D F+DPL + +++PV L
Sbjct: 699 ICENKY-LINESQVEELRSLIDRLEKVEVIEKVESVPDE-----FIDPLTFNPIRNPVKL 752
Query: 902 PTSKVTIDRSTIKAHLLSDSTDPFNRSPLKLEEVIPNVELKEKI 945
TS++T+DRST +++ DPFNR PL + VI + ELKEKI
Sbjct: 753 LTSRITVDRSTYDMLMMNGGIDPFNRMPLTEDMVIEDAELKEKI 796
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.137 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,023,441
Number of Sequences: 60738
Number of extensions: 2332587
Number of successful extensions: 6666
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 6598
Number of HSP's gapped (non-prelim): 15
length of query: 957
length of database: 30,389,216
effective HSP length: 116
effective length of query: 841
effective length of database: 23,343,608
effective search space: 19631974328
effective search space used: 19631974328
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)