ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI1477 good T KOG3205 Signal transduction mechanisms Rho GDP-dissociation inhibitor
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI1477 524444 523848 -199
(199 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL135c [T] KOG3205 Rho GDP-dissociation inhibitor 323 7e-89
SPAC6F12.06 [T] KOG3205 Rho GDP-dissociation inhibitor 140 1e-33
Hs4757768 [T] KOG3205 Rho GDP-dissociation inhibitor 131 7e-31
Hs10835002 [T] KOG3205 Rho GDP-dissociation inhibitor 127 1e-29
7293721 [T] KOG3205 Rho GDP-dissociation inhibitor 119 3e-27
Hs4502225 [T] KOG3205 Rho GDP-dissociation inhibitor 110 2e-24
CE04595 [T] KOG3205 Rho GDP-dissociation inhibitor 105 4e-23
At3g07880 [T] KOG3205 Rho GDP-dissociation inhibitor 102 3e-22
At1g62450 [T] KOG3205 Rho GDP-dissociation inhibitor 97 1e-20
At1g12070 [T] KOG3205 Rho GDP-dissociation inhibitor 89 4e-18
>YDL135c [T] KOG3205 Rho GDP-dissociation inhibitor
Length = 202
Score = 323 bits (829), Expect = 7e-89
Identities = 157/186 (84%), Positives = 169/186 (90%)
Query: 14 NDTYKVGEKKTVEEYKNLDADDEALRKWKDSLGLGGDVLPLEHPGDERRVVIQKIQLIVD 73
ND YKV KKTV+EYKNLDA+DE+L KWK+SLGL DVLPLE PGD+R+VV+QKIQL+V+
Sbjct: 17 NDQYKVSAKKTVDEYKNLDAEDESLAKWKESLGLSSDVLPLEFPGDKRKVVVQKIQLLVN 76
Query: 74 TEPAPITFDLTNEKTLKDLASKRYKIKEKSIYHLKITFKVQHEIITGLRYVQYTKKAGIA 133
TEP PITFDLTNEKT+K+LASKRYKIKE SIY LKI FKVQHEIITGLRYVQY KKAGIA
Sbjct: 77 TEPNPITFDLTNEKTIKELASKRYKIKENSIYKLKIVFKVQHEIITGLRYVQYIKKAGIA 136
Query: 134 VDKIDDHLGSYAPNTTKNPFYEVELPESEAPSGFLVRGNYSAVSKFIDDDKNNHLTLNWG 193
VDKIDDHLGSYAPNT PFYEVELPESEAPSGFL RGNYSAVSKFIDDDK NHLTLNWG
Sbjct: 137 VDKIDDHLGSYAPNTKTKPFYEVELPESEAPSGFLARGNYSAVSKFIDDDKTNHLTLNWG 196
Query: 194 VEIVKR 199
VEIVK+
Sbjct: 197 VEIVKK 202
>SPAC6F12.06 [T] KOG3205 Rho GDP-dissociation inhibitor
Length = 205
Score = 140 bits (353), Expect = 1e-33
Identities = 73/180 (40%), Positives = 108/180 (59%), Gaps = 6/180 (3%)
Query: 19 VGEKKTVEEYKNLDADDEALRKWKDSLGLGGDVLPLEHPGDERRVVIQKIQLIVDTEPAP 78
+GEKK++ EY +DA+DE+L+KWK SLG+ G D R VVI K+ L+VD P
Sbjct: 29 LGEKKSLNEYMKMDAEDESLQKWKASLGITGT--GYSPSNDRRTVVILKLSLLVDGRD-P 85
Query: 79 ITFDLTNEKTLKDLASKRYKIKEKSIYHLKITFKVQHEIITGLRYVQYTKKAGIAVDKID 138
+ ++ + +++ + K + IKE S + + + F+VQHE+I+GLRYVQ ++ G VDK
Sbjct: 86 VDVNMEDAASVEQIRKKGFTIKEGSEFKIGVKFRVQHEVISGLRYVQTVRRRGFVVDKTS 145
Query: 139 DHLGSYAPNTTKNPFYEVELPESEAPSGFLVRGNYSAVSKFIDDDKNNHLTLNWGVEIVK 198
+GSY P+ T Y+ EAP+G L RG+Y A KF+DDDK H W ++ K
Sbjct: 146 TMIGSYGPSETP---YDFTSEPDEAPTGMLARGHYEANGKFVDDDKVVHHEFVWAFDVAK 202
>Hs4757768 [T] KOG3205 Rho GDP-dissociation inhibitor
Length = 204
Score = 131 bits (329), Expect = 7e-31
Identities = 70/182 (38%), Positives = 109/182 (59%), Gaps = 8/182 (4%)
Query: 17 YKVGEKKTVEEYKNLDADDEALRKWKDSLGLGGDVLPLEHPGDERRVVIQKIQLIVDTEP 76
YK +K+++E + LD DDE+LRK+K++L G V P + VV+ + L+ + P
Sbjct: 27 YKPPAQKSIQEIQELDKDDESLRKYKEALL--GRVAVSADP-NVPNVVVTGLTLVCSSAP 83
Query: 77 APITFDLTNEKTLKDLASKRYKIKEKSIYHLKITFKVQHEIITGLRYVQYTKKAGIAVDK 136
P+ DLT + L+ + + +KE Y +KI+F+V EI++G++Y+Q+T + G+ +DK
Sbjct: 84 GPLELDLTGD--LESFKKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDK 141
Query: 137 IDDHLGSYAPNTTKNPFYEVELPESEAPSGFLVRGNYSAVSKFIDDDKNNHLTLNWGVEI 196
D +GSY P + YE P EAP G L RG+YS S+F DDDK +HL+ W + I
Sbjct: 142 TDYMVGSYGPRAEE---YEFLTPVEEAPKGMLARGSYSIKSRFTDDDKTDHLSWEWNLTI 198
Query: 197 VK 198
K
Sbjct: 199 KK 200
>Hs10835002 [T] KOG3205 Rho GDP-dissociation inhibitor
Length = 201
Score = 127 bits (318), Expect = 1e-29
Identities = 74/183 (40%), Positives = 107/183 (58%), Gaps = 10/183 (5%)
Query: 17 YKVGEKKTVEEYKNLDADDEALRKWKDSL-GLGGDVLPLEHPGDERRVVIQKIQLIVDTE 75
YK +K+++E + +D DDE+L K+K +L G G V + P VV+ ++ L+ ++
Sbjct: 24 YKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPN----VVVTRLTLVCESA 79
Query: 76 PAPITFDLTNEKTLKDLASKRYKIKEKSIYHLKITFKVQHEIITGLRYVQYTKKAGIAVD 135
P PIT DLT + L+ L + +KE S Y +KI FKV +I++GL+YVQ+T + G+ VD
Sbjct: 80 PGPITMDLTGD--LEALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVD 137
Query: 136 KIDDHLGSYAPNTTKNPFYEVELPESEAPSGFLVRGNYSAVSKFIDDDKNNHLTLNWGVE 195
K +GSY P + YE P EAP G L RG Y S F DDDK +HL+ W +
Sbjct: 138 KATFMVGSYGPRPEE---YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLS 194
Query: 196 IVK 198
I K
Sbjct: 195 IKK 197
>7293721 [T] KOG3205 Rho GDP-dissociation inhibitor
Length = 201
Score = 119 bits (298), Expect = 3e-27
Identities = 72/183 (39%), Positives = 103/183 (55%), Gaps = 7/183 (3%)
Query: 17 YKVGEKKTVEEYKNLDADDEALRKWKDSL-GLGGDVLPLEHPGDERRVVIQKIQLIVDTE 75
Y+ +KT+EE D +DE+LR++K++L G + P D R+V+++K+ L+V+
Sbjct: 22 YQAPPEKTIEEIMAADQEDESLRRYKEALLGAAQTEKIIVEPNDPRKVIVKKLALVVEGR 81
Query: 76 PAPITFDLTNEKTLKDLASKRYKIKEKSIYHLKITFKVQHEIITGLRYVQYTKKAGIAVD 135
+ DLT + L L + + IKE Y ++I F VQ EI+ GL+YVQ T + G+ VD
Sbjct: 82 D-DMELDLTGD--LSQLKKQLFVIKEGVQYKVRIDFIVQREIVHGLKYVQKTSRLGVNVD 138
Query: 136 KIDDHLGSYAPNTTKNPFYEVELPESEAPSGFLVRGNYSAVSKFIDDDKNNHLTLNWGVE 195
K+ +GSY P K P EAPSG RG YS S F DDDK+ HL +W E
Sbjct: 139 KMKHMVGSYPP---KKEIQFYLTPAEEAPSGTFSRGTYSVSSVFTDDDKHIHLEWDWTFE 195
Query: 196 IVK 198
I K
Sbjct: 196 IKK 198
>Hs4502225 [T] KOG3205 Rho GDP-dissociation inhibitor
Length = 225
Score = 110 bits (274), Expect = 2e-24
Identities = 68/179 (37%), Positives = 100/179 (54%), Gaps = 10/179 (5%)
Query: 17 YKVGEKKTVEEYKNLDADDEALRKWKDSLGLGGDVLPLEHPGDERRVVIQKIQLIVDTEP 76
Y+ +K++ E + LD DD +L K+K L G + P P V + ++ L+ + P
Sbjct: 48 YRAPGRKSLLEIRQLDPDDRSLAKYKRVLL--GPLPPAVDPSLPN-VQVTRLTLLSEQAP 104
Query: 77 APITFDLT-NEKTLKDLASKRYKIKEKSIYHLKITFKVQHEIITGLRYVQYTKKAGIAVD 135
P+ DLT N LKD + +KE Y +KI+FKV EI++GL+ + +T + G+ VD
Sbjct: 105 GPVVMDLTGNLAVLKDQV---FVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVD 161
Query: 136 KIDDHLGSYAPNTTKNPFYEVELPESEAPSGFLVRGNYSAVSKFIDDDKNNHLTLNWGV 194
K +GSY P+ + YE P EAP G LVRG Y VS F DDD+ +HL+ WG+
Sbjct: 162 KTVYMVGSYGPSAQE---YEFVTPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGL 217
>CE04595 [T] KOG3205 Rho GDP-dissociation inhibitor
Length = 191
Score = 105 bits (262), Expect = 4e-23
Identities = 66/183 (36%), Positives = 101/183 (55%), Gaps = 9/183 (4%)
Query: 17 YKVGEKKTVEEYKNLDADDEALRKWKDSL-GLGGDVLPLEHPGDERRVVIQKIQLIVDTE 75
YK +K+++E N D +DE+L+ +K L G G ++ ++P RV+++ ++L+++ +
Sbjct: 16 YKQPPQKSIDELLNADKEDESLKVYKAKLLGQGTVIVDEKNP---LRVIVRSVELLINGK 72
Query: 76 PAPITFDLTNEKTLKDLASKRYKIKEKSIYHLKITFKVQHEIITGLRYVQYTKKAGIAVD 135
A +FDL++ L + + IKE S Y L F VQ EI +GL Y K++GI V+
Sbjct: 73 TAQ-SFDLSDPAKLVN-SDLSVSIKEGSNYRLSFAFHVQREITSGLHYKHKVKRSGITVE 130
Query: 136 KIDDHLGSYAPNTTKNPFYEVELPESEAPSGFLVRGNYSAVSKFIDDDKNNHLTLNWGVE 195
+GSYAP K E + P EAPSG + RG Y SK DDD N +L W +
Sbjct: 131 NEKYMMGSYAP---KLEIQEYKSPNEEAPSGMMHRGKYKVYSKITDDDNNVYLDWQWTLH 187
Query: 196 IVK 198
I K
Sbjct: 188 ITK 190
>At3g07880 [T] KOG3205 Rho GDP-dissociation inhibitor
Length = 240
Score = 102 bits (254), Expect = 3e-22
Identities = 63/181 (34%), Positives = 96/181 (52%), Gaps = 8/181 (4%)
Query: 18 KVGEKKTVEEYKNLDADDEALRKWKDSLGLGGDVLPLEHPGDERRVVIQKIQLIVDTEPA 77
++G + T++E+ D DDE+LRKWK+ L DV + D V I + +I P
Sbjct: 63 QLGPQYTIKEHLEKDKDDESLRKWKEQLLGSVDVTNIGETLDPE-VRIDSLAIISPGRPD 121
Query: 78 PITFDLTNEKTLKDLASKRYKIKEKSIYHLKITFKVQHEIITGLRYVQYTKKAGIAVDKI 137
+ N + +KE S Y+LK TF V + I++GLRY K G+ VD+
Sbjct: 122 IVLLVPENGNP----KGMWFTLKEGSKYNLKFTFHVNNNIVSGLRYTNTVWKTGVKVDRA 177
Query: 138 DDHLGSYAPNTTKNPFYEVELPESEAPSGFLVRGNYSAVSKFIDDDKNNHLTLNWGVEIV 197
+ LG+++P P+ V +PE PSG RG+YSA +KF+DDD +L +N+ +I
Sbjct: 178 KEMLGTFSPQL--EPYNHV-MPEETTPSGMFARGSYSARTKFLDDDNKCYLEINYSFDIR 234
Query: 198 K 198
K
Sbjct: 235 K 235
>At1g62450 [T] KOG3205 Rho GDP-dissociation inhibitor
Length = 223
Score = 97.1 bits (240), Expect = 1e-20
Identities = 65/184 (35%), Positives = 97/184 (52%), Gaps = 12/184 (6%)
Query: 18 KVGEKKTVEEYKNLDADDEALRKWKDSLGLGGDVLPLEHPGDERRVVIQKIQLIV---DT 74
++G ++E D DDE+LR+WK+ L LG V+ LE G+ V++ + L + D
Sbjct: 46 ELGPMIALKEQLERDKDDESLRRWKEQL-LG--VVDLEDVGETPDPVVKILDLTIRSPDR 102
Query: 75 EPAPITFDLTNEKTLKDLASKRYKIKEKSIYHLKITFKVQHEIITGLRYVQYTKKAGIAV 134
E +T E L + + IKE S Y L F+V + I++GLRY K G+ V
Sbjct: 103 EEMVLTIP---EDGLPNPKGPWFTIKEGSKYTLVFNFRVTNNIVSGLRYNNTVWKTGVKV 159
Query: 135 DKIDDHLGSYAPNTTKNPFYEVELPESEAPSGFLVRGNYSAVSKFIDDDKNNHLTLNWGV 194
D LG+++P Y+ +PE PSG RG+YSA +KFIDDD +L +N+
Sbjct: 160 DSTKAMLGTFSPQAES---YQHVMPEEMTPSGMFARGSYSARTKFIDDDNKCYLEINYTF 216
Query: 195 EIVK 198
+I K
Sbjct: 217 DIRK 220
>At1g12070 [T] KOG3205 Rho GDP-dissociation inhibitor
Length = 223
Score = 89.0 bits (219), Expect = 4e-18
Identities = 63/184 (34%), Positives = 97/184 (52%), Gaps = 12/184 (6%)
Query: 18 KVGEKKTVEEYKNLDADDEALRKWKDSLGLGGDVLPLEHPGDERRVVIQKIQLIV---DT 74
++G ++E D DDE+LR+WK+ L LG + LE G+ +++ + L + D
Sbjct: 46 ELGPMIALKEQLEKDKDDESLRRWKEQL-LGS--VDLEEVGETPDPLVKILTLTIRSPDR 102
Query: 75 EPAPITFDLTNEKTLKDLASKRYKIKEKSIYHLKITFKVQHEIITGLRYVQYTKKAGIAV 134
E +T + K + +KE S Y L TF+V + I++GL+Y K GI V
Sbjct: 103 EDMVLTIPENGKPASK---GPWFTLKEGSKYTLIFTFRVTNNIVSGLQYSNTVWKTGIKV 159
Query: 135 DKIDDHLGSYAPNTTKNPFYEVELPESEAPSGFLVRGNYSAVSKFIDDDKNNHLTLNWGV 194
+ LG+++P P+ V E+ APSG LVRG+YS SKF+DDD +L N+
Sbjct: 160 YSRKEMLGTFSPQA--EPYTHVMFEET-APSGLLVRGSYSVKSKFVDDDNQCYLENNYTF 216
Query: 195 EIVK 198
+I K
Sbjct: 217 DIRK 220
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.135 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,228,265
Number of Sequences: 60738
Number of extensions: 535661
Number of successful extensions: 1024
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 994
Number of HSP's gapped (non-prelim): 10
length of query: 199
length of database: 30,389,216
effective HSP length: 101
effective length of query: 98
effective length of database: 24,254,678
effective search space: 2376958444
effective search space used: 2376958444
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)