ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI1759 good D KOG0653 Cell cycle control, cell division, chromosome partitioning Cyclin B and related kinase-activating proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI1759 628569 626986 -528
(528 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR199w [D] KOG0653 Cyclin B and related kinase-activating proteins 478 e-135
YPL256c [D] KOG0653 Cyclin B and related kinase-activating proteins 476 e-134
SPBC19F5.01c [D] KOG0653 Cyclin B and related kinase-activating ... 69 1e-11
YAL040c [D] KOG0653 Cyclin B and related kinase-activating proteins 52 2e-06
Hs4502613 [D] KOG0654 G2/Mitotic-specific cyclin A 52 2e-06
>YMR199w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 546
Score = 478 bits (1231), Expect = e-135
Identities = 246/469 (52%), Positives = 307/469 (65%), Gaps = 22/469 (4%)
Query: 9 ESSLGLVVTAKQTYYPIELSNAELLAHYETVQDYHQEISLNCITQSCRLKPDSKLIDQQP 68
E GL+VTAKQTYYPIELSNAELL HYET+Q+YH+EIS N + QS + KPD KLIDQQP
Sbjct: 5 EVKTGLIVTAKQTYYPIELSNAELLTHYETIQEYHEEISQNVLVQSSKTKPDIKLIDQQP 64
Query: 69 ELGPSKTRHVVVNFFFELALKTRVTNGIFYQAVRLYDRYCSKRIVLREQVKLVVATCLWL 128
E+ P +TR +V F ++L++ TRV+NGIF+ AVR YDRYCSKR+VL++Q KLVV TCLWL
Sbjct: 65 EMNPHQTREAIVTFLYQLSVMTRVSNGIFFHAVRFYDRYCSKRVVLKDQAKLVVGTCLWL 124
Query: 129 AAKTWGGCNHIINNVSVPTGGRFYGPNPRARIPRLSELIHLCNDSQTFDESMFTQMERHI 188
AAKTWGGCNHIINNVS+PTGGRFYGPNPRARIPRLSEL+H C S FDESMF QMERHI
Sbjct: 125 AAKTWGGCNHIINNVSIPTGGRFYGPNPRARIPRLSELVHYCGGSDLFDESMFIQMERHI 184
Query: 189 LNTLGWEIYEPMINDYILNADENCAIQYELYRRQLEHN----RKWLXXXXXXXXXXXXXX 244
L+TL W++YEPMINDYILN DENC IQYELY+ QL++N ++W
Sbjct: 185 LDTLNWDVYEPMINDYILNVDENCLIQYELYKNQLQNNNSNGKEWSCKRKSQSSDDSDAT 244
Query: 245 XXXXXXXXXXXXXXXXXXXX-------XXKIQLINIKKFLIDLTSWQYQLLKFEQFEVTH 297
KI+LIN+K+FLIDL+ WQY LLKFE +E+ +
Sbjct: 245 VEEHISSSPQSTGLDGDTTTMDEDEELNSKIKLINLKRFLIDLSCWQYNLLKFELYEICN 304
Query: 298 GMFQLINKFTNQELGPLLQTPIP---TGSTSDAIVDIYIDAILDCPEQLWESYKEFDGIV 354
GMF +INKFTNQ+ GP L PI +T + I I+ I++ P L E YKE GIV
Sbjct: 305 GMFSIINKFTNQDQGPFLSMPIGNDINSNTQTQVFSIIINGIVNSPPSLVEVYKEQYGIV 364
Query: 355 QFVGEVRDYQRQMEYLSQQRQI-----QYSTPTRIYQVPSAQQNFPSP-PYSQQTFSPSS 408
F+ +V+DY +++ Q + + +R + ++ + SP YS T
Sbjct: 365 PFILQVKDYNLELQKKLQLASTIDLTRKIAVNSRYFDQNASSSSVSSPSTYSSGTNYTPM 424
Query: 409 RKISTQSDNSLFSTYGVTHSSPLTPQLHSFTHNKLTPNSANGSHISLHS 457
R S QSDNS+FST + HSSP+TP H +T N+ SA S IS+ S
Sbjct: 425 RNFSAQSDNSVFSTTNIDHSSPITP--HMYTFNQFKNESACDSAISVSS 471
>YPL256c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 545
Score = 476 bits (1224), Expect = e-134
Identities = 242/465 (52%), Positives = 321/465 (68%), Gaps = 19/465 (4%)
Query: 12 LGLVVTAKQTYYPIELSNAELLAHYETVQDYHQEISLNCITQSCRLKPDSKLIDQQPELG 71
+GLV+ AK YYPIELSNAELL+H+E +Q+YHQEIS N I QSC+ KP+ KLIDQQPE+
Sbjct: 10 MGLVINAKPDYYPIELSNAELLSHFEMLQEYHQEISTNVIAQSCKFKPNPKLIDQQPEMN 69
Query: 72 PSKTRHVVVNFFFELALKTRVTNGIFYQAVRLYDRYCSKRIVLREQVKLVVATCLWLAAK 131
P +TR ++ F FEL++ TRVTNGIF+ +VRLYDRYCSKRIVLR+Q KLVVATCLWLAAK
Sbjct: 70 PVETRSNIITFLFELSVVTRVTNGIFFHSVRLYDRYCSKRIVLRDQAKLVVATCLWLAAK 129
Query: 132 TWGGCNHIINNVSVPTGGRFYGPNPRARIPRLSELIHLCNDSQTFDESMFTQMERHILNT 191
TWGGCNHIINNV +PTGGRFYGPNPRARIPRLSEL+H C D Q FDESMF QMERHIL+T
Sbjct: 130 TWGGCNHIINNVVIPTGGRFYGPNPRARIPRLSELVHYCGDGQVFDESMFLQMERHILDT 189
Query: 192 LGWEIYEPMINDYILNADENCAIQYELYRRQLEHNRKWLXXXXXXXXXXXXXXXXXXXXX 251
L W IYEPMINDY+LN DENC +QYELY Q+ ++++
Sbjct: 190 LNWNIYEPMINDYVLNVDENCLMQYELYENQVTYDKQ----CSEKRQSQLSQDSDATVDE 245
Query: 252 XXXXXXXXXXXXXXXKIQLINIKKFLIDLTSWQYQLLKFEQFEVTHGMFQLINKFTNQEL 311
KI+LIN+KKFLID+++WQY LL++E FEV+HG+F +IN+FTNQ+
Sbjct: 246 RPYQNEEEEEEDLKLKIKLINLKKFLIDVSAWQYDLLRYELFEVSHGIFSIINQFTNQDH 305
Query: 312 GPLLQTPIPTGSTSDAIVDIYIDAILDCPEQLWESYKEFDGIVQFVGEVRDY----QRQM 367
GP L TP+ + S + I+ ++ I+ P L E YK +G++ F+ +V++Y QR++
Sbjct: 306 GPFLMTPMTSESKNGEILSTLMNGIVSIPNSLMEVYKTVNGVLPFINQVKEYHLDLQRKL 365
Query: 368 EYLSQ---QRQIQYSTPTRIYQVPSAQQNFPSPPYSQQTFSPSSRKISTQSDNSLFSTYG 424
+ S R++ STP+ ++ S + PSP S Q+ +P R +S+ SDNS+FS
Sbjct: 366 QIASNLNISRKLTISTPSCSFE-NSNSTSIPSPASSSQSHTP-MRNMSSLSDNSVFSR-N 422
Query: 425 VTHSSPLTPQLHSFTHNKLTPNSANGSHISLHS---TSSMKRSYD 466
+ SSP+TP ++ F + NS GS +S++S T++ +R Y+
Sbjct: 423 MEQSSPITPSMYQFGQQQ--SNSICGSTVSVNSLVNTNNKQRIYE 465
>SPBC19F5.01c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 359
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/165 (30%), Positives = 79/165 (46%), Gaps = 24/165 (14%)
Query: 41 DYHQEISLNCITQSCRLKPDSKLIDQQPELGPSKTRHVVVNFFFELALKTRVTNGIFYQA 100
+Y ++I + IT+ + L +QQPEL S R +VNF E+ ++ +
Sbjct: 95 EYQEDIIHHLITREKNFLLNVHLSNQQPELRWSM-RPALVNFIVEIHNGFDLSIDTLPLS 153
Query: 101 VRLYDRYCSKRIVLREQVKLVVATCLWLAAKTWGGCNHIINNVSVPTGGRFYGPNPRARI 160
+ L D Y S+R+V + ++LV CLW+A+K F+ R+
Sbjct: 154 ISLMDSYVSRRVVYCKHIQLVACVCLWIASK-------------------FH--ETEDRV 192
Query: 161 PRLSELIHLCNDSQTFDESMFTQMERHILNTLGWEIYEPMINDYI 205
P L EL C + + E +F +MERHIL+TL W+I P YI
Sbjct: 193 PLLQELKLACKN--IYAEDLFIRMERHILDTLDWDISIPTPASYI 235
>YAL040c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 580
Score = 52.4 bits (124), Expect = 2e-06
Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 26/172 (15%)
Query: 27 LSNAELLAHYETVQDYHQEISLNCITQSCRLKPDSKL--IDQQPELGPSKTRHVVVNFFF 84
L EL AH+ + +Y+ + + S +P L + QP++ P K R ++ +F
Sbjct: 58 LVKRELQAHHSAISEYNNDQLDHYFRLSHTERPLYNLTNFNSQPQVNP-KMRFLIFDFIM 116
Query: 85 ELALKTRVTNGIFYQAVRLYDRYCSKRIVLREQVKLVVATCLWLAAKTWGGCNHIINNVS 144
+ ++ + + D+Y S+ I+ +L+ T LW+++K W N
Sbjct: 117 YCHTRLNLSTSTLFLTFTILDKYSSRFIIKSYNYQLLSLTALWISSKFWDSKN------- 169
Query: 145 VPTGGRFYGPNPRARIPRLSELIHLCNDSQTFDESMFTQMERHILNTLGWEI 196
R+ L L +LC + + + FT ME H+ +L W I
Sbjct: 170 --------------RMATLKVLQNLCCNQYSIKQ--FTTMEMHLFKSLDWSI 205
>Hs4502613 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 432
Score = 52.0 bits (123), Expect = 2e-06
Identities = 39/167 (23%), Positives = 77/167 (45%), Gaps = 26/167 (15%)
Query: 39 VQDYHQEISLNCITQSCRLKPDSKLIDQQPELGPSKTRHVVVNFFFELALKTRVTNGIFY 98
V DYH++I + KP + +QP++ S R ++V++ E+ + ++ N +
Sbjct: 175 VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSM-RAILVDWLVEVGEEYKLQNETLH 233
Query: 99 QAVRLYDRYCSKRIVLREQVKLVVATCLWLAAKTWGGCNHIINNVSVPTGGRFYGPNPRA 158
AV DR+ S VLR +++LV + LA+K F P
Sbjct: 234 LAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASK-------------------FEEIYP-- 272
Query: 159 RIPRLSELIHLCNDSQTFDESMFTQMERHILNTLGWEIYEPMINDYI 205
P ++E +++ +D T+ + +ME +L L +++ P +N ++
Sbjct: 273 --PEVAEFVYITDD--TYTKKQVLRMEHLVLKVLTFDLAAPTVNQFL 315
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,399,754
Number of Sequences: 60738
Number of extensions: 1240993
Number of successful extensions: 3682
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3670
Number of HSP's gapped (non-prelim): 7
length of query: 528
length of database: 30,389,216
effective HSP length: 111
effective length of query: 417
effective length of database: 23,647,298
effective search space: 9860923266
effective search space used: 9860923266
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)