ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI1784 good S KOG1426 Function unknown FOG: RCC1 domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI1784 637943 636504 -480
(480 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL097w [S] KOG1426 FOG: RCC1 domain 705 0.0
SPBC557.03c [S] KOG1426 FOG: RCC1 domain 321 2e-87
Hs4502801 [S] KOG1426 FOG: RCC1 domain 152 8e-37
ECU04g1500 [S] KOG1426 FOG: RCC1 domain 150 3e-36
7295409 [S] KOG1426 FOG: RCC1 domain 126 6e-29
7292061 [O] KOG0941 E3 ubiquitin protein ligase 119 1e-26
At5g63860 [S] KOG1426 FOG: RCC1 domain 118 2e-26
At5g16040 [S] KOG1426 FOG: RCC1 domain 108 1e-23
CE03024 [S] KOG1426 FOG: RCC1 domain 106 7e-23
At3g02300 [S] KOG1426 FOG: RCC1 domain 106 7e-23
Hs7657152 [O] KOG0941 E3 ubiquitin protein ligase 106 9e-23
At1g27060 [S] KOG1426 FOG: RCC1 domain 98 3e-20
Hs4506581_1 [S] KOG1426 FOG: RCC1 domain 96 1e-19
CE29116 [O] KOG0941 E3 ubiquitin protein ligase 94 3e-19
Hs6912330 [S] KOG1426 FOG: RCC1 domain 93 8e-19
Hs4758520 [S] KOG1426 FOG: RCC1 domain 92 1e-18
Hs4557026 [S] KOG1426 FOG: RCC1 domain 92 1e-18
7295603 [S] KOG1426 FOG: RCC1 domain 90 7e-18
At5g48330 [S] KOG1426 FOG: RCC1 domain 90 9e-18
At3g55580 [S] KOG1426 FOG: RCC1 domain 85 2e-16
7296158 [S] KOG1426 FOG: RCC1 domain 85 2e-16
At3g53830 [S] KOG1426 FOG: RCC1 domain 84 5e-16
At1g19880 [S] KOG1427 Uncharacterized conserved protein contains... 84 6e-16
At5g60870 [S] KOG1426 FOG: RCC1 domain 82 1e-15
Hs19923519 [S] KOG1426 FOG: RCC1 domain 79 2e-14
At3g02510 [S] KOG1426 FOG: RCC1 domain 79 2e-14
Hs7705931 [O] KOG0941 E3 ubiquitin protein ligase 79 2e-14
Hs4557445 [S] KOG1426 FOG: RCC1 domain 78 3e-14
At3g03790 [S] KOG1426 FOG: RCC1 domain 77 6e-14
Hs19311016_2 [S] KOG1426 FOG: RCC1 domain 75 2e-13
7300793 [S] KOG1426 FOG: RCC1 domain 69 2e-11
CE07026 [S] KOG1426 FOG: RCC1 domain 68 3e-11
At3g15430 [S] KOG1426 FOG: RCC1 domain 68 3e-11
7297063 [S] KOG1427 Uncharacterized conserved protein contains R... 67 5e-11
7301213 [R] KOG0589 Serine/threonine protein kinase 65 2e-10
At3g26100 [S] KOG1426 FOG: RCC1 domain 64 5e-10
At5g11580 [S] KOG1426 FOG: RCC1 domain 63 1e-09
Hs13540582 [S] KOG1426 FOG: RCC1 domain 62 2e-09
Hs22049475 [S] KOG1426 FOG: RCC1 domain 61 4e-09
CE19021 [S] KOG1426 FOG: RCC1 domain 60 6e-09
7296072 [S] KOG1426 FOG: RCC1 domain 58 3e-08
CE12118 [S] KOG1426 FOG: RCC1 domain 57 6e-08
Hs20547756 [S] KOG0783 Uncharacterized conserved protein contain... 56 1e-07
Hs16716337_1 [S] KOG1426 FOG: RCC1 domain 56 1e-07
CE25842 [T] KOG1428 Inhibitor of type V adenylyl cyclases/Neuron... 52 3e-06
CE06730 [T] KOG1428 Inhibitor of type V adenylyl cyclases/Neuron... 52 3e-06
7293028 [T] KOG1428 Inhibitor of type V adenylyl cyclases/Neuron... 50 1e-05
>YGL097w [S] KOG1426 FOG: RCC1 domain
Length = 482
Score = 705 bits (1819), Expect = 0.0
Identities = 331/454 (72%), Positives = 386/454 (84%), Gaps = 3/454 (0%)
Query: 29 INSQDDYKHLYRSVVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSF 88
IN+Q+DYKH+Y SV PLDIF WGTGSMCELGLGPLAKNKEVKRPRLNP LPRDEAKI+SF
Sbjct: 30 INAQEDYKHMYLSVQPLDIFCWGTGSMCELGLGPLAKNKEVKRPRLNPFLPRDEAKIISF 89
Query: 89 AAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIEST 148
A GGMHTLALD ++N+WSWG ND GALGRDTS A E+LK LNE+EST
Sbjct: 90 AVGGMHTLALDEESNVWSWGCNDVGALGRDTSNAKEQLKDMDADDSSDDEDGDLNELEST 149
Query: 149 PTKIPRDSLP--LDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQ 206
P KIPR+S P + + VQ+AATDN+S ALF NG+VYAWGTFRCNEGILGFY+D+I +Q
Sbjct: 150 PAKIPRESFPPLAEGHKVVQLAATDNMSCALFSNGEVYAWGTFRCNEGILGFYQDKIKIQ 209
Query: 207 KTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDP 266
KTPW +P FSK IVQ+A GKDHILFLDE G+V+AWGNGQQ QLGR+++ER RL+TLDP
Sbjct: 210 KTPWKVPTFSKY-NIVQLAPGKDHILFLDEEGMVFAWGNGQQNQLGRKVMERFRLKTLDP 268
Query: 267 RPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPE 326
RPFGL ++KYI+SGENH FAL+ D KL SWGLNQFGQCG+S ++EDG+LV+ P + LP+
Sbjct: 269 RPFGLRHVKYIASGENHCFALTKDNKLVSWGLNQFGQCGVSEDVEDGALVTKPKRLALPD 328
Query: 327 GVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPT 386
V I S++AGEHH+LIL++ GDLYSCGRLDMFEVGI KD LPEYTYKDVHGKAR++PLPT
Sbjct: 329 NVVIRSIAAGEHHSLILSQDGDLYSCGRLDMFEVGIPKDNLPEYTYKDVHGKARAVPLPT 388
Query: 387 KLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQD 446
KL +VP FK++AAGSHHS+A+A+NGI YSWGFGETYAVGLGP DD E PTRIKNTATQD
Sbjct: 389 KLNNVPKFKSVAAGSHHSVAVAQNGIAYSWGFGETYAVGLGPFEDDTEVPTRIKNTATQD 448
Query: 447 HSIVFIGCGGQFSISGGVKLSDEEAEKRADEMDD 480
H+I+ +GCGGQFS+SGGVKLSDE+AEKRADEMDD
Sbjct: 449 HNIILVGCGGQFSVSGGVKLSDEDAEKRADEMDD 482
>SPBC557.03c [S] KOG1426 FOG: RCC1 domain
Length = 539
Score = 321 bits (822), Expect = 2e-87
Identities = 173/428 (40%), Positives = 253/428 (58%), Gaps = 22/428 (5%)
Query: 45 LDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNI 104
L+++V+G+GSM ELG+G + V RPRLNP+L D+ +V A GGMH+ AL D +
Sbjct: 71 LNVYVFGSGSMNELGMGE-EEMDVVYRPRLNPILSTDKVGVVDLAVGGMHSAALSHDGRV 129
Query: 105 WSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRC 164
++WG ND ALGR T ++ + +E TP+K+ L LR
Sbjct: 130 YTWGVNDDYALGRLTKDQKDE----------NGDKVDNDLLEGTPSKVEG---ALSHLRV 176
Query: 165 VQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEI-TVQKTPWIIPNFSKKAKIVQ 223
++ +DNL+AA+ +NG + WGTFRC++G+LG+ + T + T +P +I Q
Sbjct: 177 TKVICSDNLTAAITDNGCCFTWGTFRCSDGVLGYSDSQKRTAEPTQMRLP------EICQ 230
Query: 224 MAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENH 283
+A G DHI+ L TG VY WGNGQQ QLGRR+LER RL+ L P+P L NI + +G H
Sbjct: 231 LATGTDHIIALTTTGKVYTWGNGQQFQLGRRMLERRRLQGLTPQPLALKNIISVGAGSYH 290
Query: 284 SFALSTDGKLYSWGLNQFGQCGISTE-LEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLI 342
SFA+ G++Y+WGLN QCGI E E+G++++ PT V EG + S++ GEHHTL
Sbjct: 291 SFAIDNKGRVYAWGLNITRQCGIEVEDEEEGAVITKPTLVDALEGYNVKSITGGEHHTLA 350
Query: 343 LAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSH 402
L + G + + GR D ++GI + LPE KD G + PT + + + + G+H
Sbjct: 351 LLEDGRVLAWGRDDRHQLGIPDNALPETVVKDEKGNNYYLSTPTIIPGLTNVIQVVCGTH 410
Query: 403 HSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQFSISG 462
H+LA+ +G VYSWG E Y VG G + +D+ PT +++ A ++ +I G GGQFSI
Sbjct: 411 HNLAVTSDGKVYSWGSAENYEVGQGDNDEDVAVPTLVRSKAIKEVAIRVAGAGGQFSIIA 470
Query: 463 GVKLSDEE 470
G+ + EE
Sbjct: 471 GIPNASEE 478
>Hs4502801 [S] KOG1426 FOG: RCC1 domain
Length = 421
Score = 152 bits (385), Expect = 8e-37
Identities = 117/439 (26%), Positives = 196/439 (43%), Gaps = 68/439 (15%)
Query: 37 HLYRSVVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTL 96
H S P + G G + +LGLG + K+P L + P D +V AGGMHT+
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMER--KKPALVSI-PED---VVQAEAGGMHTV 80
Query: 97 ALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDS 156
L ++S+G ND GALGRDTS + E P K+
Sbjct: 81 CLSKSGQVYSFGCNDEGALGRDTS---------------------VEGSEMVPGKVELQE 119
Query: 157 LPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFS 216
+ VQ++A D+ +AAL ++G V+ WG+FR N G++G + K +
Sbjct: 120 ------KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGL----LEPMKKSMVPVQVQ 169
Query: 217 KKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGR-------RILERSRLRTLDPRPF 269
+V++A+G DH++ L G +Y G G+Q QLGR R + R L P+
Sbjct: 170 LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCV 229
Query: 270 GL------DNIKYISS--GENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTE 321
L ++++ + G +FA+S +G +Y +GL+ + Q G T + +
Sbjct: 230 MLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG--TPGTESCFIPQNLT 287
Query: 322 VILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARS 381
S G+HHT+ + G YS GR + +G+ + A
Sbjct: 288 SFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEG-------------AEE 334
Query: 382 IPLPTKLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKN 441
+PT + +P+ ++A G+ A+ K+G V++WG G Y +G G +D +P +
Sbjct: 335 KSIPTLISRLPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTG-QDEDAWSPVEMMG 393
Query: 442 TATQDHSIVFIGCGGQFSI 460
++ ++ + GGQ ++
Sbjct: 394 KQLENRVVLSVSSGGQHTV 412
>ECU04g1500 [S] KOG1426 FOG: RCC1 domain
Length = 440
Score = 150 bits (380), Expect = 3e-36
Identities = 119/392 (30%), Positives = 178/392 (45%), Gaps = 72/392 (18%)
Query: 42 VVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDAD 101
V+ + +FV+G+ ++ +LGLG A++ V RL+ D+ + G +HTL LD+D
Sbjct: 79 VLQMSVFVFGSNAISQLGLGEDAESTHVPT-RLSFF---DKMSLTKVRCGSLHTLVLDSD 134
Query: 102 NNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDE 161
++SWG ND GALGRD ESTP ++ D
Sbjct: 135 GMLYSWGCNDEGALGRDGD-------------------------ESTPQRVCLDE----- 164
Query: 162 LRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKI 221
+ V + ++S AL G VY WGTFR G G +T K P I
Sbjct: 165 -KIVDMDCGASISVALTSRGHVYVWGTFRSTNGTFG-----LTPGKKISFEPVKVPLKSI 218
Query: 222 VQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPF-----GLDNIKY 276
++AG+ + LD ++ +G+ + +LGRR ER++LR L P L N ++
Sbjct: 219 TALSAGQGFVAALDSKDSIFTFGSNEFGELGRRTSERNKLRALIPDAVTTPRKRLRNYRF 278
Query: 277 --ISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVS 334
IS G NH AL+TDG+ Y WG N +GQ G + VP + I V+
Sbjct: 279 RSISCGLNHIIALNTDGEAYCWGSNLYGQLGHDKAESTFNKYKVPLD-------GIRQVA 331
Query: 335 AGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSF 394
GE+H+L + G LY CGR ++GI +A P+ +E V +
Sbjct: 332 GGENHSLFVTIDGTLYGCGRNKEGQLGIQS------------VEAVRTPMKLSIEHVETV 379
Query: 395 KAIAAGSHHSLAIAKNG-IVYSWGFGETYAVG 425
+ S++S I + G +YSWG G A+G
Sbjct: 380 R-----SYNSFNICRVGNELYSWGTGFNGALG 406
>7295409 [S] KOG1426 FOG: RCC1 domain
Length = 547
Score = 126 bits (317), Expect = 6e-29
Identities = 121/433 (27%), Positives = 193/433 (43%), Gaps = 69/433 (15%)
Query: 40 RSVVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALD 99
R V ++ V G G + +LGLG ++R RL+P+ +A V +AGGMH L L
Sbjct: 37 RRTVLGNVLVCGNGDVGQLGLG----EDILERKRLSPVAGIPDA--VDISAGGMHNLVLT 90
Query: 100 ADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPL 159
+I+S+G ND GALGRDTS + ES P I
Sbjct: 91 KSGDIYSFGCNDEGALGRDTSE---------------------DGSESKPDLIDLPG--- 126
Query: 160 DELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKA 219
+ + I+A D+ SA L E+G V+AWG+FR + G +G +T+ + +
Sbjct: 127 ---KALCISAGDSHSACLLEDGRVFAWGSFRDSHGNMG-----LTIDGNKRTPIDLMEGT 178
Query: 220 KIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERS--------RLRTLDPRPFGL 271
+A+G DH++ L G V+ G +Q QLG R+ ERS + L P +
Sbjct: 179 VCCSIASGADHLVILTTAGKVFTVGCAEQGQLG-RLSERSISGEGRRGKRDLLRPTQLII 237
Query: 272 DNIKYISS--GENHSFAL--STDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEG 327
K + N+ + S +++ GLN F Q T+ ++ +L + TE+
Sbjct: 238 TRAKPFEAIWATNYCTFMRESQTQVIWATGLNNFKQLAHETKGKEFALTPIKTEL----- 292
Query: 328 VEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTK 387
+I ++ G+HHT+IL GR + +G+ KDV K + T+
Sbjct: 293 KDIRHIAGGQHHTVILTTDLKCSVVGRPEYGRLGLG-------DVKDVVEKPTIVKKLTE 345
Query: 388 LEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDH 447
++ G S A+ +G +YSWG G +G+G D++E P + + TQ
Sbjct: 346 -----KIVSVGCGEVCSYAVTIDGKLYSWGSGVNNQLGVGDGDDELE-PIVVVSKNTQGK 399
Query: 448 SIVFIGCGGQFSI 460
++ GGQ +I
Sbjct: 400 HMLLASGGGQHAI 412
>7292061 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1057
Score = 119 bits (297), Expect = 1e-26
Identities = 107/394 (27%), Positives = 167/394 (42%), Gaps = 75/394 (19%)
Query: 46 DIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIW 105
+++ WG+ S +LGLG + +++++ P P P + + A G HTL L A ++
Sbjct: 6 ELYCWGSTSHGQLGLGGI-EDEQILTPSQIPWTP--DTAVQQVACGHRHTLFLTATGKVY 62
Query: 106 SWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCV 165
+ G+ND LG D PTK P L + +
Sbjct: 63 ACGSNDYSQLGHDL-----------------------------PTKRPLLIPELQDYVII 93
Query: 166 QIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMA 225
QI S AL + G V +WG C G LG D+ VQ P ++ K +VQ+A
Sbjct: 94 QICCGSRHSLALSDWGQVLSWGDNDC--GQLGHATDKEIVQ-LPKVVRQLVTKT-VVQIA 149
Query: 226 AGKDHILFLDETGIVYAWGNGQQQQLG-------RRILERSRLRTLDPRPFGLDNIKYIS 278
G +H L L G +Y+WG+ QLG RL TL P I+
Sbjct: 150 CGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAA-----IA 204
Query: 279 SGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEH 338
G NHSF +S G ++ WG N GQ G++ E S PT++ + + V+ G+
Sbjct: 205 CGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNR----SYPTQLKTLRTLGVRFVACGDE 260
Query: 339 HTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDV--PSFKA 396
++ L G +++CG ++G HG + + LP + ++ +
Sbjct: 261 FSVFLTNEGGVFTCGAGAYGQLG--------------HGFSSNEMLPRMVMELMGSTITQ 306
Query: 397 IAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSG 430
+A G+ H+LA+ + G YA GLG SG
Sbjct: 307 VACGNRHTLALVPSR-------GRVYAFGLGSSG 333
Score = 92.4 bits (228), Expect = 1e-18
Identities = 88/358 (24%), Positives = 155/358 (42%), Gaps = 48/358 (13%)
Query: 104 IWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELR 163
++ WG+ G LG G +E +E TP++IP +
Sbjct: 7 LYCWGSTSHGQLGL---GGIE------------------DEQILTPSQIPWTP----DTA 41
Query: 164 CVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQ 223
Q+A + L G VYA G+ ++ LG D T K P +IP I+Q
Sbjct: 42 VQQVACGHRHTLFLTATGKVYACGSNDYSQ--LG--HDLPT--KRPLLIPELQDYV-IIQ 94
Query: 224 MAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENH 283
+ G H L L + G V +WG+ QLG + R + I+ G NH
Sbjct: 95 ICCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNNH 154
Query: 284 SFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLIL 343
S AL++ G+LYSWG N +GQ G+++ D + + P + G+ + +++ G +H+ ++
Sbjct: 155 SLALTSCGELYSWGSNIYGQLGVNSP-NDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLI 213
Query: 344 AKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHH 403
+KSG ++ GR + ++G++ + RS P K + +A G
Sbjct: 214 SKSGAVFGWGRNNCGQLGLNDE------------TNRSYPTQLKTLRTLGVRFVACGDEF 261
Query: 404 SLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQFSIS 461
S+ + G V++ G G +G G S +++ P + +I + CG + +++
Sbjct: 262 SVFLTNEGGVFTCGAGAYGQLGHGFSSNEM-LPRMVME--LMGSTITQVACGNRHTLA 316
Score = 68.6 bits (166), Expect = 2e-11
Identities = 48/175 (27%), Positives = 86/175 (48%), Gaps = 18/175 (10%)
Query: 287 LSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKS 346
+++ +LY WG GQ G+ +ED +++ P+++ + V+ G HTL L +
Sbjct: 1 MASGKELYCWGSTSHGQLGLG-GIEDEQILT-PSQIPWTPDTAVQQVACGHRHTLFLTAT 58
Query: 347 GDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLA 406
G +Y+CG D ++G LP R + +P +L+D + I GS HSLA
Sbjct: 59 GKVYACGSNDYSQLG---HDLP---------TKRPLLIP-ELQDYVIIQ-ICCGSRHSLA 104
Query: 407 IAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQFSIS 461
++ G V SWG + +G + ++ P ++ T+ ++V I CG S++
Sbjct: 105 LSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTK--TVVQIACGNNHSLA 157
>At5g63860 [S] KOG1426 FOG: RCC1 domain
Length = 440
Score = 118 bits (295), Expect = 2e-26
Identities = 93/343 (27%), Positives = 153/343 (44%), Gaps = 47/343 (13%)
Query: 24 HKFVSINSQDDYKHLYRSVVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEA 83
H+ VS+ D+ Y S ++++ WG G LG G + ++ P P+
Sbjct: 67 HQIVSVTCGADHTVAY-SQSGMEVYSWGWGDFGRLGHG---NSSDLFTPL--PIKALHGI 120
Query: 84 KIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLN 143
+I A G H LA+ + + SWG N +G LG L
Sbjct: 121 RIKQIACGDSHCLAVTMEGEVQSWGRNQNGQLG-------------------------LG 155
Query: 144 EIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEI 203
+ E + +P+ + +R +AA +AA+ E+GD+Y WG R LG D +
Sbjct: 156 DTEDS--LVPQKIQAFEGIRIKMVAAGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRL 213
Query: 204 TVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRT 263
++ + K+ +A G H + + +G +Y +G + QLG LE
Sbjct: 214 VPERV-----TSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLED---HL 265
Query: 264 LDPRPFGLDN--IKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTE 321
+ + L N I IS G H+ AL++DGKLY WG N+FGQ G+ L+ S P +
Sbjct: 266 IPHKLEALSNSFISQISGGWRHTMALTSDGKLYGWGWNKFGQVGVGNNLDQCS----PVQ 321
Query: 322 VILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISK 364
V P+ ++ VS G HTL + + ++++ GR ++GI +
Sbjct: 322 VRFPDDQKVVQVSCGWRHTLAVTERNNVFAWGRGTNGQLGIGE 364
Score = 109 bits (273), Expect = 8e-24
Identities = 103/384 (26%), Positives = 160/384 (40%), Gaps = 57/384 (14%)
Query: 50 WGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADN-NIWSWG 108
WG G +LG G RP L D +IVS G HT+A ++SWG
Sbjct: 39 WGRGEDGQLGHGDAED-----RPSPTQLSALDGHQIVSVTCGADHTVAYSQSGMEVYSWG 93
Query: 109 TNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQIA 168
D G LG S + TP I L +R QIA
Sbjct: 94 WGDFGRLGHGNSSDL-----------------------FTPLPIKA----LHGIRIKQIA 126
Query: 169 ATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGK 228
D+ A+ G+V +WG + + LG D + QK I F + +I +AAG
Sbjct: 127 CGDSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQK----IQAF-EGIRIKMVAAGA 181
Query: 229 DHILFLDETGIVYAWGNGQQQQLGRRILERS-RLRTLDPRPFGLDNIKYISSGENHSFAL 287
+H + E G +Y WG G+ LG + +R+ RL G + + ++ G H+ ++
Sbjct: 182 EHTAAVTEDGDLYGWGWGRYGNLG--LGDRTDRLVPERVTSTGGEKMSMVACGWRHTISV 239
Query: 288 STDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSG 347
S G LY++G +++GQ G +LED +P ++ I +S G HT+ L G
Sbjct: 240 SYSGALYTYGWSKYGQLGHG-DLEDHL---IPHKLEALSNSFISQISGGWRHTMALTSDG 295
Query: 348 DLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAI 407
LY G +VG+ + + P+ + D ++ G H+LA+
Sbjct: 296 KLYGWGWNKFGQVGVGNNL------------DQCSPVQVRFPDDQKVVQVSCGWRHTLAV 343
Query: 408 AKNGIVYSWGFGETYAVGLGPSGD 431
+ V++WG G +G+G S D
Sbjct: 344 TERNNVFAWGRGTNGQLGIGESVD 367
Score = 107 bits (268), Expect = 3e-23
Identities = 98/381 (25%), Positives = 164/381 (42%), Gaps = 57/381 (14%)
Query: 84 KIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLN 143
K++ +AG H++AL + + + SWG + G LG
Sbjct: 16 KVLIISAGASHSVALLSGDIVCSWGRGEDGQLGH-------------------------G 50
Query: 144 EIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENG-DVYAWGTFRCNEGILGFYRDE 202
+ E P+ P LD + V + + + A ++G +VY+WG + G LG
Sbjct: 51 DAEDRPS--PTQLSALDGHQIVSVTCGADHTVAYSQSGMEVYSWGW--GDFGRLGHGNSS 106
Query: 203 ITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLR 262
P +I Q+A G H L + G V +WG Q QLG E S L
Sbjct: 107 DLFTPLP---IKALHGIRIKQIACGDSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDS-LV 162
Query: 263 TLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEV 322
+ F IK +++G H+ A++ DG LY WG ++G G L D + VP V
Sbjct: 163 PQKIQAFEGIRIKMVAAGAEHTAAVTEDGDLYGWGWGRYGNLG----LGDRTDRLVPERV 218
Query: 323 ILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSI 382
G ++ V+ G HT+ ++ SG LY+ G ++G HG
Sbjct: 219 TSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLG--------------HGDLEDH 264
Query: 383 PLPTKLEDVPS--FKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIK 440
+P KLE + + I+ G H++A+ +G +Y WG+ + VG+G + D +P +++
Sbjct: 265 LIPHKLEALSNSFISQISGGWRHTMALTSDGKLYGWGWNKFGQVGVGNNLDQC-SPVQVR 323
Query: 441 NTATQDHSIVFIGCGGQFSIS 461
D +V + CG + +++
Sbjct: 324 --FPDDQKVVQVSCGWRHTLA 342
>At5g16040 [S] KOG1426 FOG: RCC1 domain
Length = 396
Score = 108 bits (271), Expect = 1e-23
Identities = 105/434 (24%), Positives = 185/434 (42%), Gaps = 75/434 (17%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWS 106
+ WG+G +LGLG + KE+ ++ L P + +V G ++LA+ D +++
Sbjct: 7 VIAWGSGEDGQLGLGT-DEEKELASV-VDALEPFNVRSVVG---GSRNSLAICDDGKLFT 61
Query: 107 WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQ 166
WG N G LG + ESTP+ + L ++ VQ
Sbjct: 62 WGWNQRGTLGHPPE----------------------TKTESTPSLVKS----LANVKIVQ 95
Query: 167 IAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEI--TVQKTPWIIPNFSKKAKIVQM 224
A A+ + G YAWG + +DE V++ I +++ + Q+
Sbjct: 96 AAIGGWHCLAVDDQGRAYAWGGNEYGQCGEEPSKDETGRPVRRDIVIPKRCAQQLTVRQV 155
Query: 225 AAGKDHILFLDETGIVYAWGN----GQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSG 280
AAG H + L G V+ WG G +Q+ ++ R GL+N++ I+ G
Sbjct: 156 AAGGTHSVVLTREGYVWTWGQPWPPGDIKQI-----------SVPVRVQGLENVRLIAVG 204
Query: 281 ENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHT 340
H+ AL DG L++WG N++GQ G D S P V + + + ++AG H+
Sbjct: 205 AFHNLALKEDGTLWAWGNNEYGQLGTG----DTQPRSYPIPVQGLDDLTLVDIAAGGWHS 260
Query: 341 LILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAG 400
L G++Y GR + +G + D ++ +P L ++ G
Sbjct: 261 TALTNEGEVYGWGRGEHGRLG----------FGDNDKSSKMLPQKVNLLAGEDIIQVSCG 310
Query: 401 SHHSLAIAKNGIVYSWGFGETYAVGLG---PSGDDIETPT-------RIKNTATQDHS-- 448
HS+A+ ++G ++S+G G+ +G G +G +E P R +T +D
Sbjct: 311 GTHSVALTRDGRIFSFGRGDHGRLGYGRKVTTGQPLELPIHIPPPEGRFNHTDEEDDGKW 370
Query: 449 -IVFIGCGGQFSIS 461
+ CGG+ +++
Sbjct: 371 IAKHVACGGRHTLA 384
>CE03024 [S] KOG1426 FOG: RCC1 domain
Length = 569
Score = 106 bits (265), Expect = 7e-23
Identities = 103/427 (24%), Positives = 181/427 (42%), Gaps = 71/427 (16%)
Query: 70 KRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWSWGTNDSGAL---GRDTSGAVEKL 126
K+PR + + K + AGG+H+ L ++ ++ G N+ G + G + G+ ++
Sbjct: 172 KKPRKVDIFEEEGLKPLQAVAGGVHSAVLTSEGEVYMCGINEKGTVPAEGVEKEGSTDEF 231
Query: 127 KXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAW 186
K+ + E + V +AA + +AAL + G V AW
Sbjct: 232 -----------------------AKVKFEEDIEKEGKIVMLAAGASFTAALTDQGSVIAW 268
Query: 187 GTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNG 246
G R + G + + +Q+ P +I + +K+ KIV++AAG++H++ LDE G + +G+G
Sbjct: 269 GNLRNSNGNVDVHPLLHKMQEAPVVIVHQAKR-KIVKIAAGENHLVMLDEKGCLLTFGDG 327
Query: 247 QQQQLGRR----------ILERSRLRTLDPRPFGLDNIKYISSGENHSFALS-------T 289
+ QLGR + + S L P F K+ + FA
Sbjct: 328 EMGQLGRSSRTKTIRSKYMCDESGDHLLVPLRFKHKG-KFFDVVAKNVFASGFWTIVHGE 386
Query: 290 DGKLYSWGLNQFGQCGISTELED---GSLVSVPTEVILPE-----GVEIDSVSA-GEHHT 340
DGK Y++GLN + Q GI + D + V LP G E V+ G H
Sbjct: 387 DGKYYAFGLNNYAQLGIKVDEADVGQDGQDNRELRVFLPAEAPAFGAERTFVNIEGVQHV 446
Query: 341 LILAKSGDLYSCGRLDMFEVGIS----KDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKA 396
+IL G +++ G+ +G+ KD + Y + ++E
Sbjct: 447 VILGSDGKVFAMGKNTDNALGLGNWTGKDDQQHWLYDTIQ----------EIEFDSKIVG 496
Query: 397 IAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDD---IETPTRIKNTATQDHSIVFIG 453
++A S+A +++G Y+WGF T +GLG +D + P I + +SI+
Sbjct: 497 VSAKLATSIAWSEDGTAYAWGFDTTGQLGLGLKDEDEKMVSKPEEISSAHLDGYSIIGAS 556
Query: 454 CGGQFSI 460
Q ++
Sbjct: 557 ISDQHTL 563
Score = 61.2 bits (147), Expect = 3e-09
Identities = 72/281 (25%), Positives = 106/281 (37%), Gaps = 33/281 (11%)
Query: 84 KIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLN 143
KIV AAG H + LD + ++G + G LGR + + K
Sbjct: 301 KIVKIAAGENHLVMLDEKGCLLTFGDGEMGQLGRSSRTKTIRSKYMCDESGDHLL----- 355
Query: 144 EIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEI 203
P + D + + A+ + E+G YA+G N LG DE
Sbjct: 356 ----VPLRFKHKGKFFDVV-AKNVFASGFWTIVHGEDGKYYAFGLN--NYAQLGIKVDEA 408
Query: 204 TVQKT-----------PWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLG 252
V + P P F + V + G H++ L G V+A G LG
Sbjct: 409 DVGQDGQDNRELRVFLPAEAPAFGAERTFVNIE-GVQHVVILGSDGKVFAMGKNTDNALG 467
Query: 253 ------RRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGI 306
+ + T+ F I +S+ S A S DG Y+WG + GQ G+
Sbjct: 468 LGNWTGKDDQQHWLYDTIQEIEFD-SKIVGVSAKLATSIAWSEDGTAYAWGFDTTGQLGL 526
Query: 307 STELEDGSLVSVPTEVILP--EGVEIDSVSAGEHHTLILAK 345
+ ED +VS P E+ +G I S + HTLI+AK
Sbjct: 527 GLKDEDEKMVSKPEEISSAHLDGYSIIGASISDQHTLIIAK 567
Score = 53.1 bits (126), Expect = 9e-07
Identities = 80/311 (25%), Positives = 121/311 (38%), Gaps = 41/311 (13%)
Query: 148 TPTKIPR--DSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCN----EGI-LGFYR 200
T TK PR D + L+ +Q A SA L G+VY G EG+
Sbjct: 169 TTTKKPRKVDIFEEEGLKPLQAVAGGVHSAVLTSEGEVYMCGINEKGTVPAEGVEKEGST 228
Query: 201 DEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSR 260
DE K + K+ KIV +AAG L + G V AWGN + +
Sbjct: 229 DEFAKVKFE---EDIEKEGKIVMLAAGASFTAALTDQGSVIAWGN--LRNSNGNVDVHPL 283
Query: 261 LRTLDPRPFGL-----DNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTEL----- 310
L + P + I I++GENH L G L ++G + GQ G S+
Sbjct: 284 LHKMQEAPVVIVHQAKRKIVKIAAGENHLVMLDEKGCLLTFGDGEMGQLGRSSRTKTIRS 343
Query: 311 -----EDGSLVSVPTEVILPEGVEID----SVSAGEHHTLILAKSGDLYSCGRLDMFEVG 361
E G + VP +G D +V A T++ + G Y+ G + ++G
Sbjct: 344 KYMCDESGDHLLVPLR-FKHKGKFFDVVAKNVFASGFWTIVHGEDGKYYAFGLNNYAQLG 402
Query: 362 ISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAA-----GSHHSLAIAKNGIVYSW 416
I D+ + + + LP + P+F A G H + + +G V++
Sbjct: 403 IKVDE-ADVGQDGQDNRELRVFLPA---EAPAFGAERTFVNIEGVQHVVILGSDGKVFAM 458
Query: 417 GFGETYAVGLG 427
G A+GLG
Sbjct: 459 GKNTDNALGLG 469
>At3g02300 [S] KOG1426 FOG: RCC1 domain
Length = 456
Score = 106 bits (265), Expect = 7e-23
Identities = 98/393 (24%), Positives = 165/393 (41%), Gaps = 65/393 (16%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRD--------EAKIVSFAAGGMHTLAL 98
I+VWG + G +N++ K R+ LP + ++ + + G HT A+
Sbjct: 22 IYVWGYNQSGQTG-----RNEQEKLLRIPKQLPPELFGCPAGANSRWLDISCGREHTAAV 76
Query: 99 DADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLP 158
+D ++++WG N+ G LG T + K + +++S K
Sbjct: 77 ASDGSLFAWGANEYGQLGDGTEVGRKHPKK-------------VKQLQSEFVKFVSCGA- 122
Query: 159 LDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPN-FSK 217
C A + ++ WG N+G P + F
Sbjct: 123 ----FCTAAIAEPRENDGTLSTSRLWVWGQ---NQG-----------SNLPRLFSGAFPA 164
Query: 218 KAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRI----LERSRL-----RTLDPRP 268
I Q++ G H++ L E G++ AWG +Q QLGR + L+ R+ + LD P
Sbjct: 165 TTAIRQVSCGTAHVVALSEEGLLQAWGYNEQGQLGRGVTCEGLQAPRVINAYAKFLDEAP 224
Query: 269 FGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGV 328
L I +S GE H+ ALS G++Y+WGL GQ G L+ G +P V+ +GV
Sbjct: 225 -ELVKIMQLSCGEYHTAALSDAGEVYTWGLGSMGQLG-HVSLQSGDKELIPRRVVGLDGV 282
Query: 329 EIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGK---ARSIPLP 385
+ V+ G HT L+ G LY+ G ++G+ + + +G R++P+
Sbjct: 283 SMKEVACGGVHTCALSLEGALYAWGGGQAGQLGLGPQS--GFFFSVSNGSEMLLRNVPVL 340
Query: 386 TKLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGF 418
DV + +A G H+L + G + WG+
Sbjct: 341 VIPTDV---RLVACGHSHTLVYMREGRICGWGY 370
Score = 79.0 bits (193), Expect = 2e-14
Identities = 92/356 (25%), Positives = 149/356 (41%), Gaps = 72/356 (20%)
Query: 95 TLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPR 154
++++ + I+ WG N SG GR+ + ++ P ++P
Sbjct: 13 SVSIPTKSAIYVWGYNQSGQTGRNEQEKLLRI----------------------PKQLPP 50
Query: 155 DSLPLD---ELRCVQIAATDNLSAALFENGDVYAWGTFRCNE-GILGFYRDEITV-QKTP 209
+ R + I+ +AA+ +G ++AWG NE G LG D V +K P
Sbjct: 51 ELFGCPAGANSRWLDISCGREHTAAVASDGSLFAWGA---NEYGQLG---DGTEVGRKHP 104
Query: 210 WIIPNF-SKKAKIVQMAA----------GKDHILFLDETGIVYAWGNGQQQQLGRRILER 258
+ S+ K V A D L T ++ WG Q L R
Sbjct: 105 KKVKQLQSEFVKFVSCGAFCTAAIAEPRENDGTL---STSRLWVWGQNQGSNLPRLFSGA 161
Query: 259 SRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCG--ISTE-LEDGSL 315
T I+ +S G H ALS +G L +WG N+ GQ G ++ E L+ +
Sbjct: 162 FPATTA---------IRQVSCGTAHVVALSEEGLLQAWGYNEQGQLGRGVTCEGLQAPRV 212
Query: 316 VSVPTEVI--LPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVG-ISKDKLPEYTY 372
++ + + PE V+I +S GE+HT L+ +G++Y+ G M ++G +S
Sbjct: 213 INAYAKFLDEAPELVKIMQLSCGEYHTAALSDAGEVYTWGLGSMGQLGHVSLQS------ 266
Query: 373 KDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGP 428
G IP D S K +A G H+ A++ G +Y+WG G+ +GLGP
Sbjct: 267 ----GDKELIPRRVVGLDGVSMKEVACGGVHTCALSLEGALYAWGGGQAGQLGLGP 318
Score = 62.8 bits (151), Expect = 1e-09
Identities = 80/329 (24%), Positives = 132/329 (39%), Gaps = 55/329 (16%)
Query: 53 GSMCELGLGPLAKNKEVKRPRL-NPLLPRDEAKIVSFAAGGMHTLALDADNNIWSWGTND 111
G++ L +N+ PRL + P A I + G H +AL + + +WG N+
Sbjct: 136 GTLSTSRLWVWGQNQGSNLPRLFSGAFPATTA-IRQVSCGTAHVVALSEEGLLQAWGYNE 194
Query: 112 SGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDE----LRCVQI 167
G LGR + E L+ P I + LDE ++ +Q+
Sbjct: 195 QGQLGRGVT--CEGLQA--------------------PRVINAYAKFLDEAPELVKIMQL 232
Query: 168 AATDNLSAALFENGDVYAWGTFRCNEGILGFYR----DEITVQKTPWIIPNFSKKAKIVQ 223
+ + +AAL + G+VY WG + G LG D+ + + + S K +
Sbjct: 233 SCGEYHTAALSDAGEVYTWGLG--SMGQLGHVSLQSGDKELIPRRVVGLDGVSMK----E 286
Query: 224 MAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNI--------- 274
+A G H L G +YAWG GQ QLG + L N+
Sbjct: 287 VACGGVHTCALSLEGALYAWGGGQAGQLGLGPQSGFFFSVSNGSEMLLRNVPVLVIPTDV 346
Query: 275 KYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVS 334
+ ++ G +H+ +G++ WG N +GQ E S P+ V G ++ ++
Sbjct: 347 RLVACGHSHTLVYMREGRICGWGYNSYGQAA----NEKSSYAWYPSPVDWCVG-QVRKLA 401
Query: 335 AGEHHTLILAKSGDLYSCGRLDMFEVGIS 363
AG H+ +L D +S L F++ S
Sbjct: 402 AGGGHSAVLT---DAFSLKELCEFQLADS 427
>Hs7657152 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1050
Score = 106 bits (264), Expect = 9e-23
Identities = 91/367 (24%), Positives = 159/367 (42%), Gaps = 65/367 (17%)
Query: 82 EAKIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXX 141
+ + A GG H++ L D +++ G N G LG + G
Sbjct: 33 DRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREG-------------------- 72
Query: 142 LNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRD 201
P L + + +A ++ S AL + G +++WG ++G LG
Sbjct: 73 ---------NKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAG--SDGQLGLMTT 121
Query: 202 EITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGR-----RIL 256
E +V P +I +++ I+Q++ G H L L G + WG QLG
Sbjct: 122 EDSVA-VPRLIQKLNQQT-ILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQA 179
Query: 257 ERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLV 316
R+R+L+ P + +++G HSFALS G ++ WG+N GQ G+S E + S
Sbjct: 180 SPQRVRSLEGIP-----LAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRES-- 232
Query: 317 SVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVH 376
P V L ++ +S GE HT +L KSG +++ G ++G H
Sbjct: 233 --PCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLG--------------H 276
Query: 377 GKARSIPLPTKLEDVPSFKA--IAAGSHHSLA-IAKNGIVYSWGFGETYAVGLGPSGDDI 433
P ++ ++ + IA G H+LA + +G++Y++G G +G G + ++
Sbjct: 277 DSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHT-CNV 335
Query: 434 ETPTRIK 440
+ P+ +K
Sbjct: 336 KCPSPVK 342
Score = 103 bits (256), Expect = 7e-22
Identities = 82/254 (32%), Positives = 121/254 (47%), Gaps = 24/254 (9%)
Query: 215 FSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNI 274
F + ++A G +H +FL E G VY G + QLG ER + +I
Sbjct: 30 FISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGH---EREGNKPEQIGALADQHI 86
Query: 275 KYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVS 334
+++ GE+HS ALS G+L+SWG GQ G+ T ED V+VP + I VS
Sbjct: 87 IHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT-TEDS--VAVPRLIQKLNQQTILQVS 143
Query: 335 AGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSF 394
G H L LA G ++ G+ ++G+ K E+ + + RS LE +P
Sbjct: 144 CGNWHCLALAADGQFFTWGKNSHGQLGLGK----EFPSQASPQRVRS------LEGIP-L 192
Query: 395 KAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGC 454
+AAG HS A++ +G V+ WG +GL D E+P +K TQ +V+I C
Sbjct: 193 AQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDE-KDRESPCHVKLLRTQ--KVVYISC 249
Query: 455 GGQFSI----SGGV 464
G + + SGGV
Sbjct: 250 GEEHTAVLTKSGGV 263
Score = 101 bits (252), Expect = 2e-21
Identities = 78/296 (26%), Positives = 130/296 (43%), Gaps = 25/296 (8%)
Query: 166 QIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMA 225
++A N S L E+G+VY G +G LG R+ ++ + I+ +A
Sbjct: 38 EVACGGNHSVFLLEDGEVYTCGL--NTKGQLGHEREGNKPEQIGALADQ-----HIIHVA 90
Query: 226 AGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSF 285
G+ H L L + G +++WG G QLG E S + I +S G H
Sbjct: 91 CGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCL 150
Query: 286 ALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAK 345
AL+ DG+ ++WG N GQ G+ E + P V EG+ + V+AG H+ L+
Sbjct: 151 ALAADGQFFTWGKNSHGQLGLGKEFPS---QASPQRVRSLEGIPLAQVAAGGAHSFALSL 207
Query: 346 SGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSL 405
SG ++ G + ++G+S + K R P KL I+ G H+
Sbjct: 208 SGAVFGWGMNNAGQLGLSDE------------KDRESPCHVKLLRTQKVVYISCGEEHTA 255
Query: 406 AIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQFSIS 461
+ K+G V+++G G +G D++ P R+ + + I CG Q +++
Sbjct: 256 VLTKSGGVFTFGAGSCGQLGHDSMNDEV-NPRRVLELMGSE--VTQIACGRQHTLA 308
>At1g27060 [S] KOG1426 FOG: RCC1 domain
Length = 386
Score = 97.8 bits (242), Expect = 3e-20
Identities = 109/392 (27%), Positives = 169/392 (42%), Gaps = 71/392 (18%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPL--LPRDEAKIVSFAAGGMHTLALDADNNI 104
++ WG G+ +LG K ++ P+L L LP I A GG H +AL + +
Sbjct: 17 VWSWGAGTDGQLGT---TKLQDELLPQLLSLTSLP----SISMLACGGAHVIALTSGGKV 69
Query: 105 WSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRC 164
++WG SG LG LN +P+ D+
Sbjct: 70 FTWGRGSSGQLGHGD---------------------ILN------ITLPKLVSFFDDSVI 102
Query: 165 VQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQ-KTPWIIPNFSKKAKIVQ 223
Q AA + S + ++G + F C G G T+ TP + +F+ + +
Sbjct: 103 TQAAAGWSHSGFVSDSGCI-----FTCGNGSFGQLGHGDTLSLSTPAKVSHFNNDS-VKM 156
Query: 224 MAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKY--ISSGE 281
+A G H L L V +G+G++ QLG +R + L GL +++ IS+
Sbjct: 157 VACGMRHSLVLFAGNQVCGFGSGKRGQLGFSS-DRIKSVNLPCVVSGLKDVEVVRISANG 215
Query: 282 NHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTL 341
+HS A+S DG+ +SWG G CG G V P LP + V+ G +H L
Sbjct: 216 DHSAAISADGQFFSWGR---GFCG-------GPDVHAPQS--LPSPLSFREVAVGWNHAL 263
Query: 342 ILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKA--IAA 399
+L G++ F++G + +K PE + S L K+ D K IAA
Sbjct: 264 LLTVDGEV--------FKLGSTLNKQPEKQQLQIDS---SEALFEKVPDFDGVKVMQIAA 312
Query: 400 GSHHSLAIAKNGIVYSWGFGETYAVGLGPSGD 431
G+ HS A+ +NG V +WG+GE +GLG + D
Sbjct: 313 GAEHSAAVTENGEVKTWGWGEHGQLGLGNTND 344
Score = 67.4 bits (163), Expect = 5e-11
Identities = 65/238 (27%), Positives = 100/238 (41%), Gaps = 36/238 (15%)
Query: 235 DETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLY 294
+E V++WG G QLG L+ L L L +I ++ G H AL++ GK++
Sbjct: 12 EEEEQVWSWGAGTDGQLGTTKLQDELLPQLLSLT-SLPSISMLACGGAHVIALTSGGKVF 70
Query: 295 SWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGR 354
+WG GQ G L +++P V + I +AG H+ ++ SG +++CG
Sbjct: 71 TWGRGSSGQLGHGDILN----ITLPKLVSFFDDSVITQAAAGWSHSGFVSDSGCIFTCGN 126
Query: 355 LDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLE--DVPSFKAIAAGSHHSLAIAKNGI 412
++G HG S+ P K+ + S K +A G HSL +
Sbjct: 127 GSFGQLG--------------HGDTLSLSTPAKVSHFNNDSVKMVACGMRHSLVLFAGNQ 172
Query: 413 VYSWGFGETYAVGLGPSGDDIETPTR------------IKNTATQDHSIVFIGCGGQF 458
V GFG LG S D I++ ++ +A DHS I GQF
Sbjct: 173 V--CGFGSGKRGQLGFSSDRIKSVNLPCVVSGLKDVEVVRISANGDHSAA-ISADGQF 227
>Hs4506581_1 [S] KOG1426 FOG: RCC1 domain
Length = 524
Score = 95.9 bits (237), Expect = 1e-19
Identities = 84/292 (28%), Positives = 133/292 (44%), Gaps = 27/292 (9%)
Query: 165 VQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQM 224
V ++ D SA + N +Y +G+ N G LG + T K K+
Sbjct: 38 VHLSCGDEHSAVVTGNNKLYMFGSN--NWGQLGLGSKSAISKPT---CVKALKPEKVKLA 92
Query: 225 AAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHS 284
A G++H L E G VYA G + QLG E + IK +S+G N S
Sbjct: 93 ACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTS 152
Query: 285 FALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILA 344
AL+ DG+L+ WG N GQ G L++ S V VP +V + G + +S G +H+ +
Sbjct: 153 AALTEDGRLFMWGDNSEGQIG----LKNVSNVCVPQQVTI--GKPVSWISCGYYHSAFVT 206
Query: 345 KSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVP-SFKAIAAGSHH 403
G+LY G + ++G+ L G R+ P + ++P +A G H
Sbjct: 207 TDGELYVFGEPENGKLGLPNQLL---------GNHRT---PQLVSEIPEKVIQVACGGEH 254
Query: 404 SLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCG 455
++ + +N VY++G G+ +GLG + P I+N +D +I +I CG
Sbjct: 255 TVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIEN--IRDQTISYISCG 303
Score = 72.0 bits (175), Expect = 2e-12
Identities = 77/315 (24%), Positives = 129/315 (40%), Gaps = 58/315 (18%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWS 106
++++G+ + +LGLG + +P L ++ K+ A G HTL N+++
Sbjct: 56 LYMFGSNNWGQLGLG---SKSAISKPTCVKALKPEKVKLA--ACGRNHTLVSTEGGNVYA 110
Query: 107 WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQ 166
G N+ G LG L + E T S E + Q
Sbjct: 111 TGGNNEGQLG-------------------------LGDTEERNT-FHVISFFTSEHKIKQ 144
Query: 167 IAATDNLSAALFENGDVYAWGTFRCNEGILGFYR-------DEITVQK-TPWIIPNFSKK 218
++A N SAAL E+G ++ WG +EG +G ++T+ K WI
Sbjct: 145 LSAGSNTSAALTEDGRLFMWGD--NSEGQIGLKNVSNVCVPQQVTIGKPVSWI------- 195
Query: 219 AKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYIS 278
+ G H F+ G +Y +G + +LG RT + + ++
Sbjct: 196 ------SCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVA 249
Query: 279 SGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEH 338
G H+ L T+ +Y++GL QFGQ G+ T L + S P + I +S GE+
Sbjct: 250 CGGEHTVVL-TENAVYTFGLGQFGQLGLGTFLFE---TSEPKVIENIRDQTISYISCGEN 305
Query: 339 HTLILAKSGDLYSCG 353
HT ++ G +Y+ G
Sbjct: 306 HTALITDIGLMYTFG 320
>CE29116 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1019
Score = 94.4 bits (233), Expect = 3e-19
Identities = 85/368 (23%), Positives = 156/368 (42%), Gaps = 67/368 (18%)
Query: 49 VWGTGSMCELGLGPLAKNKEVKRP-RLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWSW 107
+W GS + G L + + + P+ AKI+ +AG HT+++ D +++W
Sbjct: 62 MWSVGSNMD---GQLGRGSRTEGSFSIYPVSWTSSAKIIQISAGRSHTVSVTDDGRVFAW 118
Query: 108 GTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQI 167
G+N+ G LG ++ + T PR ++++ VQ+
Sbjct: 119 GSNEHGQLGMES--------------------------KFTWQGTPRRVQEINDI--VQV 150
Query: 168 AATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAG 227
A+ N AL E G V+ WG I +R E Q + IV++ AG
Sbjct: 151 ASGSNHCIALDEGGRVFVWGEQADGRCI---HRPEPVEQLSG---------VPIVRVLAG 198
Query: 228 KDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISS--GENHSF 285
H L L +G V+ WG +LG ++ R +T +D + + + G+NH+
Sbjct: 199 ARHCLALSASGAVFTWGQNNSGELG---IDDLRPQTSVQHVHQMDGLGVVEAACGDNHTV 255
Query: 286 ALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAK 345
L+ G+ +S+G + GQCG ++E + + +++I G + ++AG HT+ + K
Sbjct: 256 LLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLI---GSHVTRIAAGACHTIAICK 312
Query: 346 SGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSL 405
G Y G ++G +GK + P K +++ + AG H +
Sbjct: 313 -GAPYPFGLNSSGQLG--------------NGKIMTQSTPRKTDELDHVTGVFAGYHQTF 357
Query: 406 AIAKNGIV 413
+ +G +
Sbjct: 358 FVRSSGTI 365
Score = 87.0 bits (214), Expect = 6e-17
Identities = 71/281 (25%), Positives = 127/281 (44%), Gaps = 40/281 (14%)
Query: 214 NFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDN 273
+++ AKI+Q++AG+ H + + + G V+AWG+ + QLG + + R +++
Sbjct: 89 SWTSSAKIIQISAGRSHTVSVTDDGRVFAWGSNEHGQLGME--SKFTWQGTPRRVQEIND 146
Query: 274 IKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSV 333
I ++SG NH AL G+++ WG E DG + P V GV I V
Sbjct: 147 IVQVASGSNHCIALDEGGRVFVWG-----------EQADGRCIHRPEPVEQLSGVPIVRV 195
Query: 334 SAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPS 393
AG H L L+ SG +++ G+ + E+GI D P+ + + VH +++ +
Sbjct: 196 LAGARHCLALSASGAVFTWGQNNSGELGID-DLRPQTSVQHVH----------QMDGLGV 244
Query: 394 FKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKN---------TAT 444
+A A G +H++ + G +S+G G G + PT + + A
Sbjct: 245 VEA-ACGDNHTVLLTHCGRTFSFGSDALGQCGFGKKVEKRTNPTAVSDLIGSHVTRIAAG 303
Query: 445 QDHSIVFI-GCGGQFSIS-----GGVKLSDEEAEKRADEMD 479
H+I G F ++ G K+ + ++ DE+D
Sbjct: 304 ACHTIAICKGAPYPFGLNSSGQLGNGKIMTQSTPRKTDELD 344
Score = 85.1 bits (209), Expect = 2e-16
Identities = 70/288 (24%), Positives = 124/288 (42%), Gaps = 44/288 (15%)
Query: 187 GTFRCNEGILGFYRDEITVQKTPWII--PNFSKKAKIVQMAAGKDHILFLDETGIVYAWG 244
G EG LG E T+Q II PN + + G+ H +FL + G +++ G
Sbjct: 7 GCGHTGEGQLGVRLSESTIQVPERIIGAPNDMDGTAVTSVTCGEQHTVFLTKDGKMWSVG 66
Query: 245 NGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQC 304
+ QLGR I IS+G +H+ +++ DG++++WG N+ GQ
Sbjct: 67 SNMDGQLGRGSRTEGSFSIYPVSWTSSAKIIQISAGRSHTVSVTDDGRVFAWGSNEHGQL 126
Query: 305 GISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISK 364
G+ ++ + P V E +I V++G +H + L + G ++ G
Sbjct: 127 GMESKF---TWQGTPRRV--QEINDIVQVASGSNHCIALDEGGRVFVWG----------- 170
Query: 365 DKLPEYTYKDVHGKARSIPLPT-KLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYA 423
+ G+ P P +L VP + + AG+ H LA++ +G V++WG +
Sbjct: 171 --------EQADGRCIHRPEPVEQLSGVPIVR-VLAGARHCLALSASGAVFTWGQNNSGE 221
Query: 424 VGLGPSGDDIETPTRIKNTATQD------------HSIVFIGCGGQFS 459
+G+ DD+ T +++ D H+++ CG FS
Sbjct: 222 LGI----DDLRPQTSVQHVHQMDGLGVVEAACGDNHTVLLTHCGRTFS 265
>Hs6912330 [S] KOG1426 FOG: RCC1 domain
Length = 458
Score = 93.2 bits (230), Expect = 8e-19
Identities = 110/439 (25%), Positives = 181/439 (41%), Gaps = 81/439 (18%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLL-PRDEAKIVSFAAGGMHTLALDADNNIW 105
+F WG S +LGLG K + +LN PR +I GG H+ + +++
Sbjct: 17 LFAWGANSYGQLGLG--HKEDVLLPQQLNDFCKPRSVRRI---TGGGGHSAVVTDGGDLF 71
Query: 106 SWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSL---PLDEL 162
G N G LG L E P P SL P+
Sbjct: 72 VCGLNKDGQLG-------------------------LGHTEDIPYFTPCKSLFGCPIQ-- 104
Query: 163 RCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTP--WIIPNFSK--K 218
Q+A + + L ENG V + C G ++ V P ++P + K
Sbjct: 105 ---QVACGWDFTIMLTENGQVLS-----CGSNSFG----QLGVPHGPRRCVVPQAIELHK 152
Query: 219 AKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTL-----DPRPFGLDN 273
K+V +AAG H + +GIV+ WG G GRR+ L R GL+N
Sbjct: 153 EKVVCIAAGLRHAVAATASGIVFQWGTG-LASCGRRLCPGQTLPLFFTAKEPSRVTGLEN 211
Query: 274 IK--YISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILP--EGVE 329
K + +G +HS +L+ G++Y WG N+ GQ + + + VP ++ + +
Sbjct: 212 SKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLA-----NEAAFLPVPQKIEAHCFQNEK 266
Query: 330 IDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLE 389
+ ++ +G H + ++G +++ GR D ++G KL Y + + +P
Sbjct: 267 VTAIWSGWTHLVAQTETGKMFTWGRADYGQLG---RKLETYEGWKLEKQDSFLPCSRPPN 323
Query: 390 DVPS-------FKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNT 442
+PS ++ GS H+LAI G+ YSWG+ E G G ++ P ++
Sbjct: 324 SMPSSPHCLTGATEVSCGSEHNLAII-GGVCYSWGWNEHGMCGDGTEA-NVWAPKPVQ-- 379
Query: 443 ATQDHSIVFIGCGGQFSIS 461
A S + +GCG S++
Sbjct: 380 ALLSSSGLLVGCGAGHSLA 398
>Hs4758520 [S] KOG1426 FOG: RCC1 domain
Length = 4834
Score = 92.4 bits (228), Expect = 1e-18
Identities = 83/293 (28%), Positives = 127/293 (43%), Gaps = 31/293 (10%)
Query: 142 LNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRD 201
L ++ + K+P S L L VQ+A A+ G VYA G G LG
Sbjct: 2972 LGGLKGSKIKVPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACG--EATNGRLGLGIS 3029
Query: 202 EITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRL 261
TV I S K V + +G H L G V++WG G +LG SR+
Sbjct: 3030 SGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGDDGKLGHF----SRM 3085
Query: 262 RTLDPR---PFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSV 318
PR I+ I+ G +HS AL++ G+LY+WGL ++G+ G D +
Sbjct: 3086 NCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHG----DNTTQLK 3141
Query: 319 PTEVILPEGVEIDSVSAG--EHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVH 376
P V + G + V+ G + TL L G ++S G D ++G
Sbjct: 3142 PKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLG--------------R 3187
Query: 377 GKARSIPLPTKLEDV--PSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLG 427
G + +P +E + I G+ SLA+ K+G+V++WG G+ + +G G
Sbjct: 3188 GGSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHG 3240
Score = 90.1 bits (222), Expect = 7e-18
Identities = 83/296 (28%), Positives = 125/296 (42%), Gaps = 37/296 (12%)
Query: 64 AKNKEVKRPRL-NPLLPRDEAKIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGA 122
A N + P+L L R+ KI + + G H LAL A ++SWG D G LG +
Sbjct: 476 AYNSDTLAPQLVQGLASRNIVKIAAHS-DGHHYLALAATGEVYSWGCGDGGRLGHGDTVP 534
Query: 123 VEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGD 182
+E+ K V IA SAA+ G+
Sbjct: 535 LEEPKVISAFSGKQAGK-----------------------HVVHIACGSTYSAAITAEGE 571
Query: 183 VYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKD--HILFLDETGIV 240
+Y WG R N G LG E + P ++ K K++ +A G L + E G V
Sbjct: 572 LYTWG--RGNYGRLGHGSSED--EAIPMLVAGL-KGLKVIDVACGSGDAQTLAVTENGQV 626
Query: 241 YAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQ 300
++WG+G +LGR + + L + LD +K + G S AL+ DG++YSWG
Sbjct: 627 WSWGDGDYGKLGRGGSDGCKTPKLIEKLQDLDVVK-VRCGSQFSIALTKDGQVYSWGKGD 685
Query: 301 FGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLD 356
+ G TE V P + +G ++ V+AG H L L + +++S G D
Sbjct: 686 NQRLGHGTE----EHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGSND 737
Score = 89.4 bits (220), Expect = 1e-17
Identities = 100/375 (26%), Positives = 153/375 (40%), Gaps = 57/375 (15%)
Query: 36 KHLYRSVVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHT 95
K L+ V ++ G + LGLG + V PR L K V+ +GG H
Sbjct: 3002 KSLFAVTVEGKVYACGEATNGRLGLG--ISSGTVPIPRQITALSSYVVKKVAVHSGGRHA 3059
Query: 96 LALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRD 155
AL D ++SWG D G LG + +K + IE+ TK RD
Sbjct: 3060 TALTVDGKVFSWGEGDDGKLGHFSRMNCDKPRL----------------IEALKTKRIRD 3103
Query: 156 SLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNF 215
IA + SAAL +G++Y WG G LG + T Q P ++
Sbjct: 3104 -----------IACGSSHSAALTSSGELYTWGL--GEYGRLG--HGDNTTQLKPKMV-KV 3147
Query: 216 SKKAKIVQMAAGK--DHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDN 273
+++Q+A G L L + G+V++WG+G +LGR E + R G
Sbjct: 3148 LLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSEGCNIPQNIERLNG-QG 3206
Query: 274 IKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSV 333
+ I G S AL+ G +++WG + + G +++ V P V G +I V
Sbjct: 3207 VCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVH----VRKPQVVEGLRGKKIVHV 3262
Query: 334 SAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPS 393
+ G H L + SG +Y+ G D + G +G PT ++ +
Sbjct: 3263 AVGALHCLAVTDSGQVYAWGDNDHGQQG--------------NGTTTVNRKPTLVQGLEG 3308
Query: 394 FK--AIAAGSHHSLA 406
K +A GS HS+A
Sbjct: 3309 QKITRVACGSSHSVA 3323
Score = 88.2 bits (217), Expect = 2e-17
Identities = 99/422 (23%), Positives = 170/422 (39%), Gaps = 66/422 (15%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWS 106
+FVWG +LG K ++K P + L +V A G A+ + +++
Sbjct: 2961 VFVWGLNDKDQLGG---LKGSKIKVPSFSETL--SALNVVQVAGGSKSLFAVTVEGKVYA 3015
Query: 107 WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDE--LRC 164
G +G LG I S IPR L ++
Sbjct: 3016 CGEATNGRLGLG--------------------------ISSGTVPIPRQITALSSYVVKK 3049
Query: 165 VQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQM 224
V + + + AL +G V++WG ++G LG + + K P +I K +I +
Sbjct: 3050 VAVHSGGRHATALTVDGKVFSWG--EGDDGKLGHF-SRMNCDK-PRLIEALKTK-RIRDI 3104
Query: 225 AAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGEN-- 282
A G H L +G +Y WG G+ +LG ++L+ + + ++ G
Sbjct: 3105 ACGSSHSAALTSSGELYTWGLGEYGRLGHGD-NTTQLKPKMVKVLLGHRVIQVACGSRDA 3163
Query: 283 HSFALSTDGKLYSWGLNQFGQCGISTELEDGSL-VSVPTEVILPEGVEIDSVSAGEHHTL 341
+ AL+ +G ++SWG FG+ G GS ++P + G + + G +L
Sbjct: 3164 QTLALTDEGLVFSWGDGDFGKLG-----RGGSEGCNIPQNIERLNGQGVCQIECGAQFSL 3218
Query: 342 ILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAI--AA 399
L KSG +++ G+ D F +G HG + P +E + K + A
Sbjct: 3219 ALTKSGVVWTWGKGDYFRLG--------------HGSDVHVRKPQVVEGLRGKKIVHVAV 3264
Query: 400 GSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQFS 459
G+ H LA+ +G VY+WG + G G + + PT ++ Q I + CG S
Sbjct: 3265 GALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVN-RKPTLVQGLEGQ--KITRVACGSSHS 3321
Query: 460 IS 461
++
Sbjct: 3322 VA 3323
Score = 87.0 bits (214), Expect = 6e-17
Identities = 71/251 (28%), Positives = 114/251 (45%), Gaps = 34/251 (13%)
Query: 176 ALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAK---IVQMAAGKDHIL 232
AL G+VY+WG C +G + D + +++ P +I FS K +V +A G +
Sbjct: 509 ALAATGEVYSWG---CGDGGRLGHGDTVPLEE-PKVISAFSGKQAGKHVVHIACGSTYSA 564
Query: 233 FLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYIS----SGENHSFALS 288
+ G +Y WG G +LG E + L GL +K I SG+ + A++
Sbjct: 565 AITAEGELYTWGRGNYGRLGHGSSEDEAIPMLVA---GLKGLKVIDVACGSGDAQTLAVT 621
Query: 289 TDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGD 348
+G+++SWG +G+ G DG P + + +++ V G ++ L K G
Sbjct: 622 ENGQVWSWGDGDYGKLGRGGS--DGC--KTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQ 677
Query: 349 LYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAI--AAGSHHSLA 406
+YS G+ D +G HG + P LE + K I AAGS H LA
Sbjct: 678 VYSWGKGDNQRLG--------------HGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLA 723
Query: 407 IAKNGIVYSWG 417
+ ++ V+SWG
Sbjct: 724 LTEDSEVHSWG 734
Score = 86.3 bits (212), Expect = 9e-17
Identities = 90/369 (24%), Positives = 148/369 (39%), Gaps = 64/369 (17%)
Query: 95 TLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPR 154
TL+ I+ WG N G LG IE K+P
Sbjct: 3945 TLSAGGSGTIYGWGHNHRGQLGG---------------------------IEGAKVKVPT 3977
Query: 155 DSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPN 214
L LR VQ+ + A+ +G +YA G G LG E TP ++ +
Sbjct: 3978 PCEALATLRPVQLIGGEQTLFAVTADGKLYATGYGA--GGRLGIGGTESV--STPTLLES 4033
Query: 215 FSKK-AKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDN 273
K V + +G H L L G VY+WG + +LG R+ RP +++
Sbjct: 4034 IQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLGHGN------RSPCDRPRVIES 4087
Query: 274 IKYI-----SSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGV 328
++ I ++G HS ++ G LY+WG ++G+ G S + L E + V
Sbjct: 4088 LRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDS--EDQLKPKLVEALQGHRV 4145
Query: 329 EIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKL 388
+ +G+ TL L ++S G D ++G G + +P K+
Sbjct: 4146 VDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLG--------------RGGSDGCKVPMKI 4191
Query: 389 EDVPSFKAIAA--GSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQD 446
+ + + GS S+A+ K+G VY+WG G+ + +G G S D + P +++ Q
Sbjct: 4192 DSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHG-SDDHVRRPRQVQ--GLQG 4248
Query: 447 HSIVFIGCG 455
++ I G
Sbjct: 4249 KKVIAIATG 4257
Score = 85.1 bits (209), Expect = 2e-16
Identities = 93/375 (24%), Positives = 157/375 (41%), Gaps = 55/375 (14%)
Query: 91 GGMHTL-ALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTP 149
GG TL A+ AD +++ G G LG G E + STP
Sbjct: 3992 GGEQTLFAVTADGKLYATGYGAGGRLG---IGGTESV--------------------STP 4028
Query: 150 TKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTP 209
T + +S+ ++ V + + AL G+VY+WG +G LG + P
Sbjct: 4029 TLL--ESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWG--EAEDGKLG--HGNRSPCDRP 4082
Query: 210 WIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPF 269
+I + + ++V +AAG H + G +Y WG G+ +LG E L
Sbjct: 4083 RVIESL-RGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLKPKLVEALQ 4141
Query: 270 GLDNIKYI-SSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGV 328
G + SG+ + L+ D ++SWG +G+ G DG VP ++ G+
Sbjct: 4142 GHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGS--DGC--KVPMKIDSLTGL 4197
Query: 329 EIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKL 388
+ V G ++ L KSG +Y+ G+ D +G HG + P ++
Sbjct: 4198 GVVKVECGSQFSVALTKSGAVYTWGKGDYHRLG--------------HGSDDHVRRPRQV 4243
Query: 389 EDVPSFK--AIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQD 446
+ + K AIA GS H + ++G VY+WG + +G G + + I+ P + A Q
Sbjct: 4244 QGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTT-NAIQRPRLV--AALQG 4300
Query: 447 HSIVFIGCGGQFSIS 461
+ + CG +++
Sbjct: 4301 KKVNRVACGSAHTLA 4315
Score = 83.6 bits (205), Expect = 6e-16
Identities = 88/364 (24%), Positives = 148/364 (40%), Gaps = 58/364 (15%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWS 106
++ G G+ LG+G + V P L + K V+ +GG H LAL ++ ++S
Sbjct: 4006 LYATGYGAGGRLGIGG---TESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYS 4062
Query: 107 WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQ 166
WG + G LG +P PR L + V
Sbjct: 4063 WGEAEDGKLGHG---------------------------NRSPCDRPRVIESLRGIEVVD 4095
Query: 167 IAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAA 226
+AA SA + GD+Y WG R G LG E Q P ++ + ++V +A
Sbjct: 4096 VAAGGAHSACVTAAGDLYTWGKGR--YGRLGHSDSE--DQLKPKLVEAL-QGHRVVDIAC 4150
Query: 227 GKD--HILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHS 284
G L L + V++WG+G +LGR + ++ GL +K + G S
Sbjct: 4151 GSGDAQTLCLTDDDTVWSWGDGDYGKLGRGGSDGCKVPMKIDSLTGLGVVK-VECGSQFS 4209
Query: 285 FALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILA 344
AL+ G +Y+WG + + G ++ V P +V +G ++ +++ G H +
Sbjct: 4210 VALTKSGAVYTWGKGDYHRLGHGSD----DHVRRPRQVQGLQGKKVIAIATGSLHCVCCT 4265
Query: 345 KSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKA--IAAGSH 402
+ G++Y+ G D ++G G +I P + + K +A GS
Sbjct: 4266 EDGEVYTWGDNDEGQLG--------------DGTTNAIQRPRLVAALQGKKVNRVACGSA 4311
Query: 403 HSLA 406
H+LA
Sbjct: 4312 HTLA 4315
Score = 83.2 bits (204), Expect = 8e-16
Identities = 75/276 (27%), Positives = 129/276 (46%), Gaps = 38/276 (13%)
Query: 159 LDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKK 218
L L QIA + L NG VY T N L P ++ + +
Sbjct: 448 LANLGVTQIACAEKRFLILSRNGRVY---TQAYNSDTLA-----------PQLVQGLASR 493
Query: 219 AKIVQMAAGKD--HILFLDETGIVYAWGNGQQQQLGRRI---LERSRLRTLDPRPFGLDN 273
IV++AA D H L L TG VY+WG G +LG LE ++ + +
Sbjct: 494 -NIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKH 552
Query: 274 IKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSV 333
+ +I+ G +S A++ +G+LY+WG +G+ G + ++ ++P V +G+++ V
Sbjct: 553 VVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSSEDE----AIPMLVAGLKGLKVIDV 608
Query: 334 S--AGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDV 391
+ +G+ TL + ++G ++S G D ++G + ++ L KL+D+
Sbjct: 609 ACGSGDAQTLAVTENGQVWSWGDGDYGKLG-----------RGGSDGCKTPKLIEKLQDL 657
Query: 392 PSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLG 427
K + GS S+A+ K+G VYSWG G+ +G G
Sbjct: 658 DVVK-VRCGSQFSIALTKDGQVYSWGKGDNQRLGHG 692
Score = 78.2 bits (191), Expect = 3e-14
Identities = 76/288 (26%), Positives = 121/288 (41%), Gaps = 46/288 (15%)
Query: 23 NHKFVSINSQDDYKHLYRSVVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDE 82
+ V I + D H +++ WG G LG G +E P++ +
Sbjct: 492 SRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEE---PKVISAFSGKQ 548
Query: 83 A--KIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXX 140
A +V A G ++ A+ A+ +++WG + G LG +S
Sbjct: 549 AGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGSS-------------------- 588
Query: 141 XLNEIESTPTKIPRDSLPLDELRCVQIA--ATDNLSAALFENGDVYAWGTFRCNEGILGF 198
E E+ P + L L+ + +A + D + A+ ENG V++WG + G LG
Sbjct: 589 ---EDEAIPMLV----AGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGD--GDYGKLG- 638
Query: 199 YRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILER 258
R KTP +I + +V++ G + L + G VY+WG G Q+LG E
Sbjct: 639 -RGGSDGCKTPKLIEKL-QDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEH 696
Query: 259 SRLRTLDPRPFGLDNIKYI--SSGENHSFALSTDGKLYSWGLNQFGQC 304
R L GL K I ++G H AL+ D +++SWG N QC
Sbjct: 697 VRYPKLLE---GLQGKKVIDVAAGSTHCLALTEDSEVHSWGSND--QC 739
Score = 77.4 bits (189), Expect = 4e-14
Identities = 66/233 (28%), Positives = 106/233 (45%), Gaps = 30/233 (12%)
Query: 229 DHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYIS--SGENHSFA 286
D L +G +Y WG+ + QLG +E ++++ P L ++ + GE FA
Sbjct: 3943 DWTLSAGGSGTIYGWGHNHRGQLGG--IEGAKVKVPTPCE-ALATLRPVQLIGGEQTLFA 3999
Query: 287 LSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPT--EVILPEGVEIDSVSAGEHHTLILA 344
++ DGKLY+ G G+ GI VS PT E I ++ +V++G H L L+
Sbjct: 4000 VTADGKLYATGYGAGGRLGIG----GTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALS 4055
Query: 345 KSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKA--IAAGSH 402
G++YS G + ++G HG P +E + + +AAG
Sbjct: 4056 SEGEVYSWGEAEDGKLG--------------HGNRSPCDRPRVIESLRGIEVVDVAAGGA 4101
Query: 403 HSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCG 455
HS + G +Y+WG G +G S D ++ P ++ A Q H +V I CG
Sbjct: 4102 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLK-PKLVE--ALQGHRVVDIACG 4151
Score = 72.8 bits (177), Expect = 1e-12
Identities = 62/248 (25%), Positives = 109/248 (43%), Gaps = 36/248 (14%)
Query: 221 IVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSG 280
+ Q+A + L L G VY L ++++ R + +K +
Sbjct: 453 VTQIACAEKRFLILSRNGRVYTQAYNSDT-LAPQLVQGLASRNI---------VKIAAHS 502
Query: 281 ENHSF-ALSTDGKLYSWGLNQFGQCGI--STELEDGSLVSVPTEVILPEGVEIDSVSAGE 337
+ H + AL+ G++YSWG G+ G + LE+ ++S + G + ++ G
Sbjct: 503 DGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGK--QAGKHVVHIACGS 560
Query: 338 HHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAI 397
++ + G+LY+ GR + +G HG + +P + + K I
Sbjct: 561 TYSAAITAEGELYTWGRGNYGRLG--------------HGSSEDEAIPMLVAGLKGLKVI 606
Query: 398 ----AAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIG 453
+G +LA+ +NG V+SWG G+ +G G S D +TP I+ QD +V +
Sbjct: 607 DVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGS-DGCKTPKLIEK--LQDLDVVKVR 663
Query: 454 CGGQFSIS 461
CG QFSI+
Sbjct: 664 CGSQFSIA 671
Score = 72.4 bits (176), Expect = 1e-12
Identities = 70/249 (28%), Positives = 106/249 (42%), Gaps = 46/249 (18%)
Query: 46 DIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIW 105
+++ WG G+ LG G +++ P L L + V+ +G TLA+ + +W
Sbjct: 571 ELYTWGRGNYGRLGHG---SSEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVW 627
Query: 106 SWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCV 165
SWG D G LGR S + TP I + L +L V
Sbjct: 628 SWGDGDYGKLGRGGSDGCK-----------------------TPKLIEK----LQDLDVV 660
Query: 166 QIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMA 225
++ S AL ++G VY+WG + + LG +E + P ++ K K++ +A
Sbjct: 661 KVRCGSQFSIALTKDGQVYSWG--KGDNQRLGHGTEEHV--RYPKLLEGLQGK-KVIDVA 715
Query: 226 AGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPF---GLD--NIKYISSG 280
AG H L L E V++WG+ Q Q LR P P GLD +I I+ G
Sbjct: 716 AGSTHCLALTEDSEVHSWGSNDQCQ------HFDTLRVTKPEPAALPGLDTKHIVGIACG 769
Query: 281 ENHSFALST 289
SFA S+
Sbjct: 770 PAQSFAWSS 778
Score = 71.6 bits (174), Expect = 2e-12
Identities = 64/248 (25%), Positives = 100/248 (39%), Gaps = 44/248 (17%)
Query: 46 DIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIW 105
D++ WG G LG + +++ +P+L L ++ +G TL L D+ +W
Sbjct: 4111 DLYTWGKGRYGRLGH---SDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVW 4167
Query: 106 SWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCV 165
SWG D G LGR S K+P L L V
Sbjct: 4168 SWGDGDYGKLGRGGSDG---------------------------CKVPMKIDSLTGLGVV 4200
Query: 166 QIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMA 225
++ S AL ++G VY WG + + LG D+ + P + K K++ +A
Sbjct: 4201 KVECGSQFSVALTKSGAVYTWG--KGDYHRLGHGSDDHV--RRPRQVQGLQGK-KVIAIA 4255
Query: 226 AGKDHILFLDETGIVYAWGNGQQQQLG---RRILERSRL-RTLDPRPFGLDNIKYISSGE 281
G H + E G VY WG+ + QLG ++R RL L + + ++ G
Sbjct: 4256 TGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGK-----KVNRVACGS 4310
Query: 282 NHSFALST 289
H+ A ST
Sbjct: 4311 AHTLAWST 4318
>Hs4557026 [S] KOG1426 FOG: RCC1 domain
Length = 4861
Score = 92.4 bits (228), Expect = 1e-18
Identities = 106/438 (24%), Positives = 184/438 (41%), Gaps = 70/438 (15%)
Query: 29 INSQDDYKHLYRSVVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSF 88
IN D+ + + P D W G C++ L ++ ++ N ++P A SF
Sbjct: 3973 INGMDEQIMSWATSRPED---WHLGGKCDVYLWGAGRHGQLAEAGRNVMVP---AAAPSF 4026
Query: 89 A------AGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXL 142
+ G T + A+ + + G G LG+ S + L
Sbjct: 4027 SQAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVT---- 4082
Query: 143 NEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDE 202
+ V +D S AL E+G+V++WG + G LG +
Sbjct: 4083 --------------------QLVTSCGSDGHSMALTESGEVFSWGDG--DYGKLGHGNSD 4120
Query: 203 ITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLR 262
Q+ P I + ++VQM+ G H + G ++ +GNG +LG L + +
Sbjct: 4121 R--QRRPRQIEALQGE-EVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLG---LGNTSNK 4174
Query: 263 TLDPRPFGLDN--IKYISSGENHSFALSTDGKL-YSWGLNQFGQCGISTELEDGSLVSVP 319
L R L+ I ++ G NH+ A+S DG + +++G +G+ G+ S P
Sbjct: 4175 KLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSS----P 4230
Query: 320 TEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKA 379
++ + G+ I V+ G ++ L K G +Y+ G+ + LPE ++ H +
Sbjct: 4231 QKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIG-------LPEGRARN-HNRP 4282
Query: 380 RSIPLPTK--LEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPT 437
+ IP+ +EDV A G+ H+LA+A NG VY+WG +GLG + + + PT
Sbjct: 4283 QQIPVLAGVIIEDV------AVGAEHTLALASNGDVYAWGSNSEGQLGLGHT-NHVREPT 4335
Query: 438 RIKNTATQDHSIVFIGCG 455
+ T Q ++ I G
Sbjct: 4336 LV--TGLQGKNVRQISAG 4351
Score = 86.7 bits (213), Expect = 7e-17
Identities = 85/313 (27%), Positives = 131/313 (41%), Gaps = 29/313 (9%)
Query: 145 IESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEIT 204
+E T KI + L I A + + +G V A G LG ++ T
Sbjct: 386 VEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQST 445
Query: 205 VQKTPWIIPNFSKKAKIVQMAAGKD-HILFLDETGIVYAWGNGQQQQLGRRILERSRLRT 263
++K + KK V + G D H L G V++WG+G +LG +
Sbjct: 446 LKKLTFEPHRSIKK---VSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPK 502
Query: 264 LDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVI 323
L P + +S+G HS A++ DG+LY+WG FG+ G D + ++PT +
Sbjct: 503 LIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHG----DSNSRNIPT--L 556
Query: 324 LPEGVEIDSVSAGEHHTLILAKSG-DLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSI 382
+ + + VS G HT+ L+K G ++S G D ++G HG +
Sbjct: 557 VKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLG--------------HGDTNRV 602
Query: 383 PLPTKLEDVPS--FKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIK 440
P +E + + + AGS SLA+ G VY+WG G +G G S P I+
Sbjct: 603 YKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGA--CLGCGSSEATALRPKLIE 660
Query: 441 NTATQDHSIVFIG 453
A V IG
Sbjct: 661 ELAATRIVDVSIG 673
Score = 84.3 bits (207), Expect = 4e-16
Identities = 95/397 (23%), Positives = 161/397 (39%), Gaps = 60/397 (15%)
Query: 46 DIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIW 105
+++VWG+ S +L G K + +P+L P +A+ + AG T + D ++
Sbjct: 373 EVYVWGSNSSHQLVEGTQEK---ILQPKLAPSF--SDAQTIE--AGQYCTFVISTDGSVR 425
Query: 106 SWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCV 165
+ G G LG S LK T P S+ +
Sbjct: 426 ACGKGSYGRLGLGDSNNQSTLKKL--------------------TFEPHRSIK----KVS 461
Query: 166 QIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMA 225
+D + A G+V++WG + G LG + QK P +I + +V ++
Sbjct: 462 SSKGSDGHTLAFTTEGEVFSWGDG--DYGKLG--HGNSSTQKYPKLIQGPLQGKVVVCVS 517
Query: 226 AGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSF 285
AG H + E G +Y WG G +LG + TL + N+ +S G +H+
Sbjct: 518 AGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVK---DISNVGEVSCGSSHTI 574
Query: 286 ALSTDGK-LYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILA 344
ALS DG+ ++S+G G+ G D + V P + +G+ I V AG +L L
Sbjct: 575 ALSKDGRTVWSFGGGDNGKLGHG----DTNRVYKPKVIEALQGMFIRKVCAGSQSSLALT 630
Query: 345 KSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAI--AAGSH 402
+G +Y+ G G S+ + P +E++ + + + + G
Sbjct: 631 STGQVYAWGCGACLGCGSSE---------------ATALRPKLIEELAATRIVDVSIGDS 675
Query: 403 HSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRI 439
H LA++ + VY+WG G G S I P ++
Sbjct: 676 HCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKV 712
Score = 84.0 bits (206), Expect = 5e-16
Identities = 84/296 (28%), Positives = 126/296 (42%), Gaps = 42/296 (14%)
Query: 46 DIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIW 105
++F WG G +LG G + K P+L P +V +AG H+ A+ D ++
Sbjct: 478 EVFSWGDGDYGKLGHG---NSSTQKYPKLIQG-PLQGKVVVCVSAGYRHSAAVTEDGELY 533
Query: 106 SWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCV 165
+WG D G LG S + + PT + +D + E+ C
Sbjct: 534 TWGEGDFGRLGHGDSNS-----------------------RNIPTLV-KDISNVGEVSC- 568
Query: 166 QIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMA 225
+ + AL ++G W + G LG + D V K P +I I ++
Sbjct: 569 ----GSSHTIALSKDGRT-VWSFGGGDNGKLG-HGDTNRVYK-PKVIEALQGMF-IRKVC 620
Query: 226 AGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSF 285
AG L L TG VYAWG G LG E + LR I +S G++H
Sbjct: 621 AGSQSSLALTSTGQVYAWGCGAC--LGCGSSEATALRPKLIEELAATRIVDVSIGDSHCL 678
Query: 286 ALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTL 341
ALS D ++Y+WG N GQCG + ++ P +V +G+ I +SAG H+L
Sbjct: 679 ALSHDNEVYAWGNNSMGQCG---QGNSTGPITKPKKVSGLDGIAIQQISAGTSHSL 731
Score = 79.3 bits (194), Expect = 1e-14
Identities = 76/268 (28%), Positives = 107/268 (39%), Gaps = 48/268 (17%)
Query: 35 YKHLYRSVVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMH 94
Y+H +++ WG G LG G R P L +D + + + G H
Sbjct: 520 YRHSAAVTEDGELYTWGEGDFGRLGHGD-------SNSRNIPTLVKDISNVGEVSCGSSH 572
Query: 95 TLALDADNN-IWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIP 153
T+AL D +WS+G D+G LG + V K K IE+
Sbjct: 573 TIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKV----------------IEALQGMFI 616
Query: 154 RDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIP 213
R ++ A S AL G VYAWG C LG E T + P +I
Sbjct: 617 R-----------KVCAGSQSSLALTSTGQVYAWGCGAC----LGCGSSEATALR-PKLIE 660
Query: 214 NFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDN 273
+ +IV ++ G H L L VYAWGN Q G+ + T + GLD
Sbjct: 661 ELAA-TRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQG--NSTGPITKPKKVSGLDG 717
Query: 274 --IKYISSGENHSF---ALSTDGKLYSW 296
I+ IS+G +HS AL D ++ +W
Sbjct: 718 IAIQQISAGTSHSLAWTALPRDRQVVAW 745
Score = 69.7 bits (169), Expect = 9e-12
Identities = 58/231 (25%), Positives = 107/231 (46%), Gaps = 26/231 (11%)
Query: 234 LDETGIVYAWGNGQQQQLGRRILERSRLRTLDPR-PFGLDNIKYISSGENHSFALSTDGK 292
+ ET VY WG+ QL +E ++ + L P+ + + I +G+ +F +STDG
Sbjct: 368 VSETCEVYVWGSNSSHQL----VEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGS 423
Query: 293 LYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEG--VEIDSVSAGEHHTLILAKSGDLY 350
+ + G +G+ G+ +L + E P ++ S + HTL G+++
Sbjct: 424 VRACGKGSYGRLGLGDSNNQSTLKKLTFE---PHRSIKKVSSSKGSDGHTLAFTTEGEVF 480
Query: 351 SCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAKN 410
S G D ++G +Y K + G PL K+ ++AG HS A+ ++
Sbjct: 481 SWGDGDYGKLGHGNSSTQKYP-KLIQG-----PLQGKV-----VVCVSAGYRHSAAVTED 529
Query: 411 GIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQFSIS 461
G +Y+WG G+ +G G S + PT +K+ + ++ + CG +I+
Sbjct: 530 GELYTWGEGDFGRLGHGDS-NSRNIPTLVKDIS----NVGEVSCGSSHTIA 575
Score = 68.9 bits (167), Expect = 2e-11
Identities = 75/255 (29%), Positives = 107/255 (41%), Gaps = 43/255 (16%)
Query: 35 YKHLYRSVVPLD--IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGG 92
+KH +VV D +F +G G LGLG + K +R + + +I A G
Sbjct: 4143 FKH--SAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPER-----VTALEGYQIGQVACGL 4195
Query: 93 MHTLALDADNN-IWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTK 151
HTLA+ AD + +W++G D G LG S A +S+P K
Sbjct: 4196 NHTLAVSADGSMVWAFGDGDYGKLGLGNSTA-----------------------KSSPQK 4232
Query: 152 IPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWI 211
I L + ++A S AL ++G VY +G R ++G P
Sbjct: 4233 ID----VLCGIGIKKVACGTQFSVALTKDGHVYTFGQDR----LIGLPEGRARNHNRPQQ 4284
Query: 212 IPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGL 271
IP + I +A G +H L L G VYAWG+ + QLG R TL G
Sbjct: 4285 IPVLA-GVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVTGLQG- 4342
Query: 272 DNIKYISSGENHSFA 286
N++ IS+G HS A
Sbjct: 4343 KNVRQISAGRCHSAA 4357
>7295603 [S] KOG1426 FOG: RCC1 domain
Length = 4669
Score = 90.1 bits (222), Expect = 7e-18
Identities = 78/293 (26%), Positives = 128/293 (43%), Gaps = 32/293 (10%)
Query: 142 LNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRD 201
L ++ + K+P S + LR + IA + ++G VYA G LG +
Sbjct: 2999 LGGLKGSKVKVPTFSQTISRLRPIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLGVTHN 3058
Query: 202 EITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLG---RRILER 258
+ P + KK V + +G H L L G V++WG G+ +LG R L++
Sbjct: 3059 VPLPHQLPVLRQYVVKK---VAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGNRTTLDK 3115
Query: 259 SRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSV 318
RL I+ ++ G +HS A+S+ G+LY+WGL ++G+ G D +
Sbjct: 3116 PRL----VEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHG----DNTTQLK 3167
Query: 319 PTEVILPEGVEIDSVSAGEH--HTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVH 376
P V G + V+ G TL L + G ++S G D ++G
Sbjct: 3168 PKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLG--------------R 3213
Query: 377 GKARSIPLPTKLEDVPSFKA--IAAGSHHSLAIAKNGIVYSWGFGETYAVGLG 427
G + P ++E + I G+ SLA+ + G V++WG G+ Y +G G
Sbjct: 3214 GGSEGSDTPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWGKGDYYRLGHG 3266
Score = 88.2 bits (217), Expect = 2e-17
Identities = 84/317 (26%), Positives = 134/317 (41%), Gaps = 42/317 (13%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWS 106
++ G G+ LGLG V P P+L + K V+ +GG H LAL D ++S
Sbjct: 3040 VYACGEGTNGRLGLGV---THNVPLPHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFS 3096
Query: 107 WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQ 166
WG + G LG ++K + +E+ K RD
Sbjct: 3097 WGEGEDGKLGHGNRTTLDKPRL----------------VEALRAKKIRD----------- 3129
Query: 167 IAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAA 226
+A + SAA+ G++Y WG G LG + T Q P ++ + + ++VQ+A
Sbjct: 3130 VACGSSHSAAISSQGELYTWGL--GEYGRLG--HGDNTTQLKPKLVTALAGR-RVVQVAC 3184
Query: 227 GK--DHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHS 284
G L L E G V++WG+G +LGR E S R G+ + I G S
Sbjct: 3185 GSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGI-GVVQIECGAQFS 3243
Query: 285 FALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILA 344
AL+ G++++WG + + G + V P + G + V+ G H L +
Sbjct: 3244 LALTRAGEVWTWGKGDYYRLGHGGDQH----VRKPQPIGGLRGRRVIHVAVGALHCLAVT 3299
Query: 345 KSGDLYSCGRLDMFEVG 361
+G +Y+ G D + G
Sbjct: 3300 DAGQVYAWGDNDHGQQG 3316
Score = 84.0 bits (206), Expect = 5e-16
Identities = 84/324 (25%), Positives = 140/324 (42%), Gaps = 41/324 (12%)
Query: 142 LNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRD 201
L +E + K P L LR VQ+A + A+ +G ++A G + G LG
Sbjct: 4062 LGGLEGSRIKTPTPCEALSLLRPVQLAGGEQSLFAVTPDGKLFATGYG--SGGRLGVGGS 4119
Query: 202 EITVQKTPWIIPNFSKK-----AKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLG---R 253
+ W IP K V + +G H L L G VYAWG G+ +LG R
Sbjct: 4120 D------SWAIPTLLGSLQHVFVKKVAVNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNR 4173
Query: 254 RILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDG 313
+R +L ++ I+ G HS A++ G + +WG ++G+ G + ED
Sbjct: 4174 MSYDRPKL----VEHLNGMSVADIACGSAHSAAITASGHVLTWGKGRYGRLGHG-DSEDQ 4228
Query: 314 SLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYK 373
+ ++ ++I + +G+ TL + +++S G D ++G
Sbjct: 4229 LRPKLVEALLGYRAIDI-ACGSGDAQTLCITDDDNVWSWGDGDYGKLG------------ 4275
Query: 374 DVHGKARSIPLPTKLEDVPSFKAIAA--GSHHSLAIAKNGIVYSWGFGETYAVGLGPSGD 431
G + LP K+E + + GS S+A+ K+G VY+WG G+ + +G G S D
Sbjct: 4276 --RGGSDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHG-SVD 4332
Query: 432 DIETPTRIKNTATQDHSIVFIGCG 455
+ P ++ A Q I+ I G
Sbjct: 4333 HVRRPKKV--AALQGKKIISIATG 4354
Score = 79.3 bits (194), Expect = 1e-14
Identities = 74/289 (25%), Positives = 128/289 (43%), Gaps = 29/289 (10%)
Query: 176 ALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLD 235
AL G+VYAWG +G LG + + ++ + P ++ + + + + +A G H +
Sbjct: 4150 ALTTEGEVYAWG--EGEDGKLG-HGNRMSYDR-PKLVEHLNGMS-VADIACGSAHSAAIT 4204
Query: 236 ETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYI-SSGENHSFALSTDGKLY 294
+G V WG G+ +LG E L G I SG+ + ++ D ++
Sbjct: 4205 ASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDDDNVW 4264
Query: 295 SWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGR 354
SWG +G+ G DG +P ++ G+ + V G ++ L KSG +Y+ G+
Sbjct: 4265 SWGDGDYGKLGRGGS--DGC--KLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGK 4320
Query: 355 LDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFK--AIAAGSHHSLAIAKNGI 412
D +G HG + P K+ + K +IA GS H +A + +G
Sbjct: 4321 GDFHRLG--------------HGSVDHVRRPKKVAALQGKKIISIATGSLHCVACSDSGE 4366
Query: 413 VYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQFSIS 461
VY+WG + +G G + I+ P + A Q IV + CG +++
Sbjct: 4367 VYTWGDNDEGQLGDG-TVTAIQRPRLV--AALQGKHIVKVTCGSAHTLA 4412
Score = 78.2 bits (191), Expect = 3e-14
Identities = 67/259 (25%), Positives = 118/259 (44%), Gaps = 31/259 (11%)
Query: 212 IPNFSK---KAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDP-- 266
+P FS+ + + + +A G + + + G VYA G G +LG + L P
Sbjct: 3009 VPTFSQTISRLRPIHIAGGSKSLFIVSQDGKVYACGEGTNGRLGLGVTHNVPLPHQLPVL 3068
Query: 267 RPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPE 326
R + + + + SG H+ AL+ DGK++SWG + G+ G + + P V
Sbjct: 3069 RQYVVKKVA-VHSGGKHALALTLDGKVFSWGEGEDGKLGHGNR----TTLDKPRLVEALR 3123
Query: 327 GVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPT 386
+I V+ G H+ ++ G+LY+ G + +G HG + P
Sbjct: 3124 AKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLG--------------HGDNTTQLKPK 3169
Query: 387 KLEDVPSFKAI--AAGSH--HSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNT 442
+ + + + A GS +LA+ ++G V+SWG G+ +G G S + +TP I+
Sbjct: 3170 LVTALAGRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGS-EGSDTPHEIERL 3228
Query: 443 ATQDHSIVFIGCGGQFSIS 461
+ +V I CG QFS++
Sbjct: 3229 S--GIGVVQIECGAQFSLA 3245
Score = 76.6 bits (187), Expect = 7e-14
Identities = 80/298 (26%), Positives = 127/298 (41%), Gaps = 47/298 (15%)
Query: 71 RPRLNPLLPRDEAKIVSFAAGG----MHTLALDADNNIWSWGTNDSGALGRDTSGAVEKL 126
+P PL + A V + G H LA+D+++N +SWGT + LG + A
Sbjct: 600 KPEAEPLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTHA---- 655
Query: 127 KXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQ-IAATDNLSAALFENGDVYA 185
+ PTKI E CVQ + + SAA+ G++
Sbjct: 656 -------------------RAVPTKI-----AALEQHCVQSVYCGCSYSAAITCGGNLLT 691
Query: 186 WGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKI-VQMAAGKDHILFLDETGIVYAWG 244
WG R LG + + P ++ S + V + +G H L L G+V+AWG
Sbjct: 692 WG--RGTYARLGHGNSD--DRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWG 747
Query: 245 NGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQC 304
+G +LG S L L ++ + +G S ALS++G+LY+WG C
Sbjct: 748 DGDYGKLGNGNCNGSLQPILVE---SLPRVQRVFAGSQFSVALSSEGQLYTWGK---ATC 801
Query: 305 GISTELEDGSL--VSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEV 360
+ +L + S+ SVP V + I V+ H L L+ SG+++ GR D ++
Sbjct: 802 -LGHQLVERSVQGCSVPRLVSSLQHKRIVDVAVSVAHCLALSSSGEVFGWGRNDSQQI 858
Score = 73.6 bits (179), Expect = 6e-13
Identities = 65/246 (26%), Positives = 96/246 (38%), Gaps = 42/246 (17%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWS 106
+ WG G LG G +++ RP+L L A ++ +G TL + D+N+WS
Sbjct: 4209 VLTWGKGRYGRLGHGD---SEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDDDNVWS 4265
Query: 107 WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQ 166
WG D G LGR S K+P L L V+
Sbjct: 4266 WGDGDYGKLGRGGSDGC---------------------------KLPYKIESLAGLGVVK 4298
Query: 167 IAATDNLSAALFENGDVYAWGT---FRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQ 223
+ S AL ++G VY WG R G + R V + KI+
Sbjct: 4299 VECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAAL--------QGKKIIS 4350
Query: 224 MAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENH 283
+A G H + ++G VY WG+ + QLG + + L G +K ++ G H
Sbjct: 4351 IATGSLHCVACSDSGEVYTWGDNDEGQLGDGTVTAIQRPRLVAALQGKHIVK-VTCGSAH 4409
Query: 284 SFALST 289
+ ALST
Sbjct: 4410 TLALST 4415
Score = 72.0 bits (175), Expect = 2e-12
Identities = 64/221 (28%), Positives = 101/221 (44%), Gaps = 28/221 (12%)
Query: 240 VYAWGNGQQQQLGRRILERSRLRTLDP-RPFGLDNIKYISSGENHSFALSTDGKLYSWGL 298
+Y WG+ + QLG LE SR++T P L ++ GE FA++ DGKL++ G
Sbjct: 4051 IYGWGHNHRGQLGG--LEGSRIKTPTPCEALSLLRPVQLAGGEQSLFAVTPDGKLFATGY 4108
Query: 299 NQFGQCGISTELEDGSLVSVPTEVILPEGVEID--SVSAGEHHTLILAKSGDLYSCGRLD 356
G+ G+ ++PT + + V + +V++G H L L G++Y+ G +
Sbjct: 4109 GSGGRLGVG----GSDSWAIPTLLGSLQHVFVKKVAVNSGGKHCLALTTEGEVYAWGEGE 4164
Query: 357 MFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDV--PSFKAIAAGSHHSLAIAKNGIVY 414
++G HG S P +E + S IA GS HS AI +G V
Sbjct: 4165 DGKLG--------------HGNRMSYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVL 4210
Query: 415 SWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCG 455
+WG G +G G S D + P ++ A + + I CG
Sbjct: 4211 TWGKGRYGRLGHGDSEDQLR-PKLVE--ALLGYRAIDIACG 4248
Score = 65.1 bits (157), Expect = 2e-10
Identities = 61/224 (27%), Positives = 99/224 (43%), Gaps = 30/224 (13%)
Query: 240 VYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLN 299
V WG ++QLG + ++ T L I +I+ G F +S DGK+Y+ G
Sbjct: 2988 VMVWGLNDKEQLGGLKGSKVKVPTFSQTISRLRPI-HIAGGSKSLFIVSQDGKVYACGEG 3046
Query: 300 QFGQCGISTELEDGSLVSVPTEVILPE----GVEIDSVSAGEHHTLILAKSGDLYSCGRL 355
G+ G+ G +VP LP V+ +V +G H L L G ++S G
Sbjct: 3047 TNGRLGL------GVTHNVPLPHQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWGEG 3100
Query: 356 DMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKA--IAAGSHHSLAIAKNGIV 413
+ ++G HG ++ P +E + + K +A GS HS AI+ G +
Sbjct: 3101 EDGKLG--------------HGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGEL 3146
Query: 414 YSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQ 457
Y+WG GE +G G + ++ P + TA +V + CG +
Sbjct: 3147 YTWGLGEYGRLGHGDNTTQLK-PKLV--TALAGRRVVQVACGSR 3187
Score = 63.9 bits (154), Expect = 5e-10
Identities = 48/192 (25%), Positives = 91/192 (47%), Gaps = 25/192 (13%)
Query: 230 HILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDN--IKYISSGENHSFAL 287
H L +D Y+WG G+ +LG + R + + L+ ++ + G ++S A+
Sbjct: 627 HFLAIDSNHNAYSWGTGEDHRLGHG---DTHARAVPTKIAALEQHCVQSVYCGCSYSAAI 683
Query: 288 STDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVI-LPEGVEID-SVSAGEHHTLILAK 345
+ G L +WG + + G +D SL PT V+ L + + +D ++ +G+ H+L L
Sbjct: 684 TCGGNLLTWGRGTYARLGHGNS-DDRSL---PTLVVALSDHMVVDVALGSGDAHSLALTS 739
Query: 346 SGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSL 405
G +++ G D ++G +G P +E +P + + AGS S+
Sbjct: 740 EGLVFAWGDGDYGKLG--------------NGNCNGSLQPILVESLPRVQRVFAGSQFSV 785
Query: 406 AIAKNGIVYSWG 417
A++ G +Y+WG
Sbjct: 786 ALSSEGQLYTWG 797
Score = 58.2 bits (139), Expect = 3e-08
Identities = 58/261 (22%), Positives = 107/261 (40%), Gaps = 50/261 (19%)
Query: 212 IPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGL 271
+P S + +I Q+A + +L L + G +Y W RL + P +
Sbjct: 565 VPTLSCRFQIKQVACCETQMLILSQEGKLYTW----------------RLAKPEAEPLPM 608
Query: 272 DNIK---YISSGEN----HSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVIL 324
+ + +IS + H A+ ++ YSWG + + G D +VPT++
Sbjct: 609 EEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHG----DTHARAVPTKIAA 664
Query: 325 PEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPL 384
E + SV G ++ + G+L + GR +G HG + L
Sbjct: 665 LEQHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLG--------------HGNSDDRSL 710
Query: 385 PTKLEDVPSFK----AIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIK 440
PT + + A+ +G HSLA+ G+V++WG G+ +G G ++ P ++
Sbjct: 711 PTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQ-PILVE 769
Query: 441 NTATQDHSIVFIGCGGQFSIS 461
+ + + G QFS++
Sbjct: 770 SLP----RVQRVFAGSQFSVA 786
Score = 52.4 bits (124), Expect = 2e-06
Identities = 72/308 (23%), Positives = 114/308 (36%), Gaps = 57/308 (18%)
Query: 26 FVSINSQDDYKHLYRSVVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKI 85
F+SI + +H + + WGTG LG G R + ++ +
Sbjct: 616 FISIAGHCEGRHFLAIDSNHNAYSWGTGEDHRLGHGDTH-----ARAVPTKIAALEQHCV 670
Query: 86 VSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEI 145
S G ++ A+ N+ +WG LG S +
Sbjct: 671 QSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNS-----------------------DD 707
Query: 146 ESTPTKIP--RDSLPLDELRCVQIAATDNLSAALFENGDVYAWGT---FRCNEGILGFYR 200
S PT + D + +D V + + D S AL G V+AWG + G
Sbjct: 708 RSLPTLVVALSDHMVVD----VALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSL 763
Query: 201 DEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSR 260
I V+ P ++ ++ AG + L G +Y W G+ LG +++ERS
Sbjct: 764 QPILVESLP----------RVQRVFAGSQFSVALSSEGQLYTW--GKATCLGHQLVERSV 811
Query: 261 LRTLDPR---PFGLDNIKYISSGENHSFALSTDGKLYSWGLN---QFGQCGISTE--LED 312
PR I ++ H ALS+ G+++ WG N Q +S+E L
Sbjct: 812 QGCSVPRLVSSLQHKRIVDVAVSVAHCLALSSSGEVFGWGRNDSQQICPASVSSEPLLRT 871
Query: 313 GSLVSVPT 320
LVS+PT
Sbjct: 872 PILVSLPT 879
>At5g48330 [S] KOG1426 FOG: RCC1 domain
Length = 454
Score = 89.7 bits (221), Expect = 9e-18
Identities = 108/460 (23%), Positives = 180/460 (38%), Gaps = 107/460 (23%)
Query: 47 IFVWGTGSMCELGLGPLA---KNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNN 103
+ +G G++ LGL + + P + LP D I S +AG H+LA+ +
Sbjct: 46 VMSFGDGNLGALGLSSSSIPGMGMDAYEPTVVSNLPSD---ISSISAGHYHSLAVTSSGE 102
Query: 104 IWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELR 163
IW+WG ND G LGR + + S P ++ L+ +
Sbjct: 103 IWAWGRNDEGQLGRIVIDS--------------------RDSRSEPKRVEG----LENVN 138
Query: 164 CVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQ 223
A+ +SAA+ ++G ++ WG R G LG + I + P + N + + +V+
Sbjct: 139 VQAAFASGVVSAAIGDDGSLWVWG--RSKRGQLGL-GNGIIEARVPSRVENLAAE-HVVK 194
Query: 224 MAAGKDHILFLDETGIVYAWGNGQQQQLGR--RILERSRLRTL----------------- 264
++ G H L L G V+ WG ++G LE S L ++
Sbjct: 195 VSLGWGHALALTVDGKVFGWGYVADGRVGNVGLPLEASLLDSITDGSMKGHHAAGDLNLE 254
Query: 265 -------------DPRPFGLD----------NIKYISSGENHSFALSTDGKLYSWGLNQF 301
+ P + + I+ G +HS L DG L S G N +
Sbjct: 255 AAEKKVVEAMSKENDMPIAWEPCLVEETCNEKVADIACGSDHSLILCHDGTLLSAGSNIY 314
Query: 302 GQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGD--LYSCGRLDMFE 359
GQ G S + V + I S++AG H+L + G+ + S G +
Sbjct: 315 GQLGRSKQDLGMKPVDITESPI--------SIAAGLGHSLAICNRGERNILSWGWNRSRQ 366
Query: 360 VGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFG 419
+G GK ++P + D S +++AG HSL + + G + WG G
Sbjct: 367 LG--------------RGKPENLPREVEGFDGESPASVSAGRVHSLCVTEKGEAWVWGCG 412
Query: 420 ETYAVGLGPSGDDIETPTR-------IKNTATQDHSIVFI 452
+ +GLG S D+ E ++ A DHS++ +
Sbjct: 413 KNGRLGLGSSSDEPEPMLLEDVEGCVLQAVAGFDHSLILV 452
Score = 65.5 bits (158), Expect = 2e-10
Identities = 74/293 (25%), Positives = 121/293 (41%), Gaps = 44/293 (15%)
Query: 209 PWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRP 268
P ++ N + I ++AG H L + +G ++AWG + QLGR +++ R+ R
Sbjct: 74 PTVVSNLP--SDISSISAGHYHSLAVTSSGEIWAWGRNDEGQLGRIVIDSRDSRSEPKRV 131
Query: 269 FGLDNIKYISSGENH--SFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPE 326
GL+N+ ++ + S A+ DG L+ WG ++ GQ G+ + + VP+ V
Sbjct: 132 EGLENVNVQAAFASGVVSAAIGDDGSLWVWGRSKRGQLGLGNGIIE---ARVPSRVENLA 188
Query: 327 GVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVG--------ISKDKLPEYTYKDVH-- 376
+ VS G H L L G ++ G + VG D + + + K H
Sbjct: 189 AEHVVKVSLGWGHALALTVDGKVFGWGYVADGRVGNVGLPLEASLLDSITDGSMKGHHAA 248
Query: 377 ----------------GKARSIPL---PTKLEDVPSFKA--IAAGSHHSLAIAKNGIVYS 415
K +P+ P +E+ + K IA GS HSL + +G + S
Sbjct: 249 GDLNLEAAEKKVVEAMSKENDMPIAWEPCLVEETCNEKVADIACGSDHSLILCHDGTLLS 308
Query: 416 WGFGETYAVG-----LGPSGDDIETPTRIKNTATQDHSIVFIGCGGQFSISGG 463
G +G LG DI T + I A HS+ G + +S G
Sbjct: 309 AGSNIYGQLGRSKQDLGMKPVDI-TESPISIAAGLGHSLAICNRGERNILSWG 360
Score = 60.1 bits (144), Expect = 7e-09
Identities = 81/336 (24%), Positives = 130/336 (38%), Gaps = 62/336 (18%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWS 106
++VWG +LGLG V R+ L K+ + G H LAL D ++
Sbjct: 158 LWVWGRSKRGQLGLGNGIIEARVPS-RVENLAAEHVVKV---SLGWGHALALTVDGKVFG 213
Query: 107 WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQ 166
WG G +G L DS+ ++
Sbjct: 214 WGYVADGRVGNVGLPLEASLL---------------------------DSITDGSMKGHH 246
Query: 167 IAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAA 226
A NL AA E V A +++ + P ++ + K+ +A
Sbjct: 247 AAGDLNLEAA--EKKVVEAMSK-----------ENDMPIAWEPCLVEETCNE-KVADIAC 292
Query: 227 GKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGL-DNIKYISSGENHSF 285
G DH L L G + + G+ QLGR + L +P + ++ I++G HS
Sbjct: 293 GSDHSLILCHDGTLLSAGSNIYGQLGR------SKQDLGMKPVDITESPISIAAGLGHSL 346
Query: 286 ALSTDGK--LYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLIL 343
A+ G+ + SWG N+ S +L G ++P EV +G SVSAG H+L +
Sbjct: 347 AICNRGERNILSWGWNR------SRQLGRGKPENLPREVEGFDGESPASVSAGRVHSLCV 400
Query: 344 AKSGD--LYSCGRLDMFEVGISKDKLPEYTYKDVHG 377
+ G+ ++ CG+ +G S D+ +DV G
Sbjct: 401 TEKGEAWVWGCGKNGRLGLGSSSDEPEPMLLEDVEG 436
Score = 57.8 bits (138), Expect = 4e-08
Identities = 54/188 (28%), Positives = 91/188 (47%), Gaps = 24/188 (12%)
Query: 278 SSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGE 337
+SGE + DG L + GL+ G+ + + ++VS LP +I S+SAG
Sbjct: 39 TSGERRTVMSFGDGNLGALGLSSSSIPGMGMDAYEPTVVSN-----LPS--DISSISAGH 91
Query: 338 HHTLILAKSGDLYSCGRLDMFEVGI----SKDKLPEYTYKDVHGKARSIPLPTKLEDVPS 393
+H+L + SG++++ GR D ++G S+D E K V G LE+V
Sbjct: 92 YHSLAVTSSGEIWAWGRNDEGQLGRIVIDSRDSRSEP--KRVEG----------LENVNV 139
Query: 394 FKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIG 453
A A+G S AI +G ++ WG + +GLG + P+R++N A + V +G
Sbjct: 140 QAAFASGVV-SAAIGDDGSLWVWGRSKRGQLGLGNGIIEARVPSRVENLAAEHVVKVSLG 198
Query: 454 CGGQFSIS 461
G +++
Sbjct: 199 WGHALALT 206
>At3g55580 [S] KOG1426 FOG: RCC1 domain
Length = 488
Score = 85.1 bits (209), Expect = 2e-16
Identities = 104/447 (23%), Positives = 172/447 (38%), Gaps = 103/447 (23%)
Query: 53 GSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWSWGTN-- 110
GS +LG + K + P PL P E + AG H +A+ + +++WG
Sbjct: 89 GSTDDLGQSYVTSGKHGETPEPFPLPP--EVCVQKAEAGWAHCVAVTENQQVYTWGWREC 146
Query: 111 ----------DSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIES--TPTKIPRDSLP 158
D + R+ S + E++ E PTK R S P
Sbjct: 147 IPTGRVFGQVDGDSCERNISFSTEQVSSSSQGKKSSGGTSSQVEGRGGGEPTKKRRIS-P 205
Query: 159 LDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKK 218
+ A +N S + D I + P ++ + +
Sbjct: 206 SKQ-------AAENSSQS------------------------DNIDLSALPCLV-SLAPG 233
Query: 219 AKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLG-----RRILERSRLRTLDPRPFGL-- 271
+IV +AAG H L L + G V+ WG G + QLG R + + ++P +G
Sbjct: 234 VRIVSVAAGGRHTLALSDIGQVWGWGYGGEGQLGLGSRVRLVSSPHPIPCIEPSSYGKAT 293
Query: 272 -----------------DNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGS 314
+K I+ G HS ++ G L ++G +GQCG + ++ S
Sbjct: 294 SSGVNMSSVVQCGRVLGSYVKKIACGGRHSAVITDTGALLTFGWGLYGQCGQGSTDDELS 353
Query: 315 LVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKD 374
PT V G+ I+ V+AG HT + GD+Y+ G ++G D
Sbjct: 354 ----PTCVSSLLGIRIEEVAAGLWHTTCASSDGDVYAFGGNQFGQLGTGCD--------- 400
Query: 375 VHGKARSIPLPTKLEDVPSF-----KAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPS 429
+A ++P KL + P+ K I+ G+ H+ I G V+ WG+ + +G+G
Sbjct: 401 ---QAETLP---KLLEAPNLENVNVKTISCGARHTAVITDEGRVFCWGWNKYGQLGIGDV 454
Query: 430 GD-DIETPTRIKNTATQDHSIVFIGCG 455
D + RIK+ ++ I CG
Sbjct: 455 IDRNAPAEVRIKDCFPKN-----IACG 476
Score = 77.0 bits (188), Expect = 6e-14
Identities = 68/267 (25%), Positives = 117/267 (43%), Gaps = 21/267 (7%)
Query: 84 KIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLN 143
+IVS AAGG HTLAL +W WG G LG + + +
Sbjct: 235 RIVSVAAGGRHTLALSDIGQVWGWGYGGEGQLGLGSRVRLVSSPHPIPCIEPSSYGKATS 294
Query: 144 EIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDV--YAWGTF-RCNEGILGFYR 200
+ + + + ++ +IA SA + + G + + WG + +C +G
Sbjct: 295 SGVNMSSVVQCGRVLGSYVK--KIACGGRHSAVITDTGALLTFGWGLYGQCGQGSTD--- 349
Query: 201 DEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSR 260
DE++ ++ +I ++AAG H G VYA+G Q QLG +
Sbjct: 350 DELSPTCVSSLLG-----IRIEEVAAGLWHTTCASSDGDVYAFGGNQFGQLGTGCDQAET 404
Query: 261 LRTLDPRPFGLDNI--KYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSV 318
L L P L+N+ K IS G H+ ++ +G+++ WG N++GQ GI ++ + V
Sbjct: 405 LPKLLEAP-NLENVNVKTISCGARHTAVITDEGRVFCWGWNKYGQLGIGDVIDRNAPAEV 463
Query: 319 PTEVILPEGVEIDSVSAGEHHTLILAK 345
+ P+ +++ G HTL+L +
Sbjct: 464 RIKDCFPK-----NIACGWWHTLLLGQ 485
>7296158 [S] KOG1426 FOG: RCC1 domain
Length = 454
Score = 85.1 bits (209), Expect = 2e-16
Identities = 94/407 (23%), Positives = 171/407 (41%), Gaps = 65/407 (15%)
Query: 77 LLPRDEAKIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXX 136
+L +D++KI ++ + ++ ++ WG ++GALG T+ V+K K
Sbjct: 23 VLAQDKSKIKEYSPKTTDS----HEHRVYVWGFQETGALGLQTN--VKKAKERYT----- 71
Query: 137 XXXXXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGIL 196
E+ PT++ + +E+ V + A ++G+ +G+ + L
Sbjct: 72 -------EMVHHPTRLQFSNN--NEITDVAAGYGFTVYAVNRDDGETL-FGSGLNTDSQL 121
Query: 197 GFY----------RDEI---TVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAW 243
GF D I T K P + + ++ M+AG+ H++ L + G ++
Sbjct: 122 GFQVKGNPNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTL 181
Query: 244 GNGQQQQLGRRILERSRL-------RTLDPRPFGL-DNIKYISSGENHSFALSTDGKLYS 295
GN Q GR I+E R R G D + + G++HS L+ G++Y+
Sbjct: 182 GNNSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYT 241
Query: 296 WGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRL 355
G GQ G G + + +V E +I +S L L ++GD + G
Sbjct: 242 CGWGADGQTGQGNYHTAGQITLIGGDV---EKEKIVRLSCSSDCVLALNEAGDAFGWGNS 298
Query: 356 DMFEVGISKDKLPEYTYKDVHGKARSIPLPTKL-EDVPSFKAIAAGSHHSLAIAKNGIVY 414
+ ++ S ++ +IP KL + + K +AAG +A+ G+VY
Sbjct: 299 EYGQLDDS----------ELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVY 348
Query: 415 SWGFGETYAVGLGPSGDDIETPTRI------KNTATQDHSIVFIGCG 455
+WGFG +G GP + P + +N + + ++V IGCG
Sbjct: 349 TWGFG---ILGFGPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIGCG 392
Score = 68.6 bits (166), Expect = 2e-11
Identities = 81/356 (22%), Positives = 140/356 (38%), Gaps = 63/356 (17%)
Query: 69 VKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKX 128
+K PR+ D ++ S +AG H + L + I++ G N G GR +E+ +
Sbjct: 144 IKLPRVQGETDED-MRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQCGR---SIIEEERY 199
Query: 129 XXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVY--AW 186
+I ++ + E VQ+ + S L + G +Y W
Sbjct: 200 SKSALIH---------------RISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGW 244
Query: 187 GTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNG 246
G +G G Q T +I +K KIV+++ D +L L+E G + WGN
Sbjct: 245 GA----DGQTGQGNYHTAGQIT--LIGGDVEKEKIVRLSCSSDCVLALNEAGDAFGWGNS 298
Query: 247 QQQQLGRRILERSRLRTLDPRPF----GLDNIKYISSGENHSFALSTDGKLYSWGLNQFG 302
+ QL L +++ PR + IK +++G + AL+ G +Y+WG FG
Sbjct: 299 EYGQLDDSELAETQINI--PRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWG---FG 353
Query: 303 QCGISTELEDGSLVSVPTEVILP--------EGVEIDSVSAGEHHTLILAKSGDLYSCGR 354
G +E S P ++ P + S+ G H + GDL+ G+
Sbjct: 354 ILGFGPFVEQ---TSKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNSDGDLFMWGK 410
Query: 355 LDMFEVGISKDKLPEYTYK-DVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAK 409
+G+ K + +K ++GK +A G H++A+ K
Sbjct: 411 NRFGHLGLGHKKDQFFPFKAAINGKVTK---------------VAYGVDHTIALCK 451
Score = 64.7 bits (156), Expect = 3e-10
Identities = 90/404 (22%), Positives = 159/404 (39%), Gaps = 45/404 (11%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRL----NPLLPRDEAKIVSFAAG-GMHTLALDAD 101
++VWG LGL K + + + L + +I AAG G A++ D
Sbjct: 46 VYVWGFQETGALGLQTNVKKAKERYTEMVHHPTRLQFSNNNEITDVAAGYGFTVYAVNRD 105
Query: 102 NN--IWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPL 159
+ ++ G N LG G I T K+PR
Sbjct: 106 DGETLFGSGLNTDSQLGFQVKGNPNDPANLDVI------------IYPTAIKLPRVQGET 153
Query: 160 DE-LRCVQIAATDNLSAALFENGDVYAWGTF---RCNEGILGFYRDEITVQKTPWIIPNF 215
DE +R ++A L +NG ++ G +C I+ +E K+ +I
Sbjct: 154 DEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQCGRSII----EEERYSKSA-LIHRI 208
Query: 216 S------KKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPF 269
S K+ ++VQ+ G+DH +FL + G +Y G G Q G+ + TL
Sbjct: 209 SQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQITLIGGDV 268
Query: 270 GLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGV- 328
+ I +S + AL+ G + WG +++GQ S E + +++P + L + +
Sbjct: 269 EKEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQLDDSELAE--TQINIPRALKLTKSIG 326
Query: 329 EIDSVSAGEHHTLILAKSGDLYSCG-RLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTK 387
+I V+AG + L G +Y+ G + F + + P++ + G+
Sbjct: 327 KIKDVAAGGSFCMALNDQGLVYTWGFGILGFGPFVEQTSKPQHLLPPLFGR-------ND 379
Query: 388 LEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGD 431
+ + +I G H A+ +G ++ WG +GLG D
Sbjct: 380 FSNETTVVSIGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKD 423
>At3g53830 [S] KOG1426 FOG: RCC1 domain
Length = 487
Score = 84.0 bits (206), Expect = 5e-16
Identities = 77/286 (26%), Positives = 119/286 (40%), Gaps = 38/286 (13%)
Query: 84 KIVSFAAGGMHTLALDADNN---------------IWSWGTNDSGALGRDTS----GAVE 124
+I S A GG HTLAL +++ IW WG G LG + +
Sbjct: 215 RITSVATGGRHTLALSVEDSFEDDHVFTEVSDLGQIWGWGYGGEGQLGLGSRIKMVSSPH 274
Query: 125 KLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDV- 183
+ L++ +T T P ++ + SAA+ + G +
Sbjct: 275 LIPCLESIGSGKERSFILHQGGTTTTSAQASREPGQYIKAISCGGRH--SAAITDAGGLI 332
Query: 184 -YAWGTF-RCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVY 241
+ WG + +C G + V + K ++ +AAG H + + G VY
Sbjct: 333 TFGWGLYGQCGHGNTNDQLRPMAVSEV--------KSVRMESVAAGLWHTICISSDGKVY 384
Query: 242 AWGNGQQQQLGRRILERSRL-RTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQ 300
A+G Q QLG L R LD + + K +S G HS L+ DG+L WG N+
Sbjct: 385 AFGGNQFGQLGTGTDHAEILPRLLDGQNLEGKHAKAVSCGARHSAVLAEDGQLLCWGWNK 444
Query: 301 FGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKS 346
+GQ G L D + ++PT+V L +G + V+ G HTL+L S
Sbjct: 445 YGQLG----LGDTNDRNIPTQVQL-DGCRLRKVACGWWHTLLLGDS 485
Score = 69.7 bits (169), Expect = 9e-12
Identities = 96/431 (22%), Positives = 164/431 (37%), Gaps = 87/431 (20%)
Query: 53 GSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWSWGTND- 111
GS + G +A K + P PL EA +V ++G H + ++WG +
Sbjct: 77 GSTDDEGQSYVASGKHGETPEPFPL--PTEAPVVQASSGWAHCAVVTETGEAFTWGWKEC 134
Query: 112 ---SGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNE---IESTPTKIPRDSLPLDE---- 161
+G+ SG+ E+ NE + K R S DE
Sbjct: 135 IPSKDPVGKQQSGSSEQGDIASQGSNAASGTTLQNENQKVGEESVKRRRVSTAKDETEGH 194
Query: 162 -------------------LRCVQIAATDNLSAAL-----FENGDVYA--------WGTF 189
+R +A + AL FE+ V+ WG
Sbjct: 195 TSGGDFFATTPSLVSVGLGVRITSVATGGRHTLALSVEDSFEDDHVFTEVSDLGQIWGWG 254
Query: 190 RCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQ 249
EG LG I + +P +IP + +GK+ L + G
Sbjct: 255 YGGEGQLGL-GSRIKMVSSPHLIPCLES------IGSGKERSFILHQGGTTTT------- 300
Query: 250 QLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTE 309
S + +P + IK IS G HS A++ G L ++G +GQCG
Sbjct: 301 ---------SAQASREPGQY----IKAISCGGRHSAAITDAGGLITFGWGLYGQCGHGNT 347
Query: 310 LEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPE 369
+ ++V +EV + V ++SV+AG HT+ ++ G +Y+ G ++G D
Sbjct: 348 NDQLRPMAV-SEV---KSVRMESVAAGLWHTICISSDGKVYAFGGNQFGQLGTGTD---- 399
Query: 370 YTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPS 429
H + L + + KA++ G+ HS +A++G + WG+ + +GLG +
Sbjct: 400 ------HAEILPRLLDGQNLEGKHAKAVSCGARHSAVLAEDGQLLCWGWNKYGQLGLGDT 453
Query: 430 GDDIETPTRIK 440
+D PT+++
Sbjct: 454 -NDRNIPTQVQ 463
>At1g19880 [S] KOG1427 Uncharacterized conserved protein contains RCC1 domain
Length = 530
Score = 83.6 bits (205), Expect = 6e-16
Identities = 70/269 (26%), Positives = 127/269 (47%), Gaps = 29/269 (10%)
Query: 220 KIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRR-ILERSRLRTLDPRPFGLDNIKYI- 277
+ V H + LD G Y WG ++ QLG +++R R + GL K +
Sbjct: 59 RFVATGCASFHCVALDVEGRCYTWGRNEKGQLGHGDMIQRDRPTVVS----GLSKHKIVK 114
Query: 278 -SSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAG 336
++G NH+ +S DG+ +G N++GQ G+ + + + S P ++ + E+ +V+ G
Sbjct: 115 AAAGRNHTVVVSDDGQSLGFGWNKYGQLGLGSAKNE--VESTPLPCVVSD--EVTNVACG 170
Query: 337 EHHTLILAKS--GDLYSCGRLDMFEVGISKDKLPEYTYKD--VHGKARSIPLPTKLEDVP 392
T+ L+ + + + G ++G D E+ KD V + P P + +
Sbjct: 171 ADFTVWLSSTEGASILTAGLPQYGQLGHGTDN--EFNMKDSSVRLAYEAQPRPKAIASLA 228
Query: 393 --SFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRI----KNTATQD 446
+ +A G++H++A+ KNG VY+WGFG +G D+ P RI +N
Sbjct: 229 GETIVKVACGTNHTVAVDKNGYVYTWGFGGYGRLGHREQKDE-WAPRRIDVFQRNNVLPP 287
Query: 447 HSIVFIG-----CGGQFSISGGVKLSDEE 470
++I+ G CGGQ + G +K + ++
Sbjct: 288 NAILSAGSANSACGGQLYMWGKIKNNGDD 316
Score = 61.6 bits (148), Expect = 2e-09
Identities = 83/408 (20%), Positives = 161/408 (39%), Gaps = 83/408 (20%)
Query: 69 VKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKX 128
V RL PL+ + + V+ H +ALD + ++WG N+ G LG ++
Sbjct: 45 VSPTRLRPLVGVN-IRFVATGCASFHCVALDVEGRCYTWGRNEKGQLGHGDMIQRDR--- 100
Query: 129 XXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGT 188
PT + L + + V+ AA N + + ++G +G
Sbjct: 101 --------------------PTVVSG----LSKHKIVKAAAGRNHTVVVSDDGQSLGFGW 136
Query: 189 FRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDET--GIVYAWGNG 246
+ + LG ++E+ P ++ + ++ +A G D ++L T + G
Sbjct: 137 NKYGQLGLGSAKNEVESTPLPCVVSD-----EVTNVACGADFTVWLSSTEGASILTAGLP 191
Query: 247 QQQQLGRRI-----LERSRLRTL---DPRPFGL-----DNIKYISSGENHSFALSTDGKL 293
Q QLG ++ S +R PRP + + I ++ G NH+ A+ +G +
Sbjct: 192 QYGQLGHGTDNEFNMKDSSVRLAYEAQPRPKAIASLAGETIVKVACGTNHTVAVDKNGYV 251
Query: 294 YSWGLNQFGQCGISTELEDGSLVSVPT----EVILPEGVEIDSVSAGEHHTLILAKSGDL 349
Y+WG +G+ G + ++ + + V+ P + +SAG ++ A G L
Sbjct: 252 YTWGFGGYGRLGHREQKDEWAPRRIDVFQRNNVLPPNAI----LSAGSANS---ACGGQL 304
Query: 350 YSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKA--IAAGSHHSLAI 407
Y G++ K+ ++ Y P + D+ + + +GS H
Sbjct: 305 YMWGKI--------KNNGDDWMY------------PKPMMDLSGWNLRWMDSGSMHHFVG 344
Query: 408 AKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCG 455
A + + SWG + +G GP+G + K + ++ + CG
Sbjct: 345 ADSSCI-SWGHAQYGELGYGPNGQKSSAAPK-KVDMLEGMHVMGVACG 390
Score = 55.5 bits (132), Expect = 2e-07
Identities = 68/255 (26%), Positives = 117/255 (45%), Gaps = 31/255 (12%)
Query: 176 ALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLD 235
AL G Y WG R +G LG ++ + P ++ SK KIV+ AAG++H + +
Sbjct: 72 ALDVEGRCYTWG--RNEKGQLG--HGDMIQRDRPTVVSGLSKH-KIVKAAAGRNHTVVVS 126
Query: 236 ETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGL-DNIKYISSGENHSFAL-STDG-K 292
+ G +G + QLG + T P P + D + ++ G + + L ST+G
Sbjct: 127 DDGQSLGFGWNKYGQLGLGSAKNEVEST--PLPCVVSDEVTNVACGADFTVWLSSTEGAS 184
Query: 293 LYSWGLNQFGQCGISTE----LEDGSLVSV------PTEVILPEGVEIDSVSAGEHHTLI 342
+ + GL Q+GQ G T+ ++D S+ P + G I V+ G +HT+
Sbjct: 185 ILTAGLPQYGQLGHGTDNEFNMKDSSVRLAYEAQPRPKAIASLAGETIVKVACGTNHTVA 244
Query: 343 LAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSH 402
+ K+G +Y+ G +G +++ E+ + + R+ LP ++AGS
Sbjct: 245 VDKNGYVYTWGFGGYGRLG-HREQKDEWAPRRIDVFQRNNVLPPN-------AILSAGSA 296
Query: 403 HSLAIAKNGIVYSWG 417
+S A G +Y WG
Sbjct: 297 NS---ACGGQLYMWG 308
Score = 55.1 bits (131), Expect = 2e-07
Identities = 86/384 (22%), Positives = 136/384 (35%), Gaps = 90/384 (23%)
Query: 43 VPLDI----FVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLAL 98
V LD+ + WG +LG G + ++R R + + KIV AAG HT+ +
Sbjct: 71 VALDVEGRCYTWGRNEKGQLGHGDM-----IQRDRPTVVSGLSKHKIVKAAAGRNHTVVV 125
Query: 99 DADNNIWSWGTNDSG---------------------------ALGRDTSGAVEKLKXXXX 131
D +G N G A G D + + +
Sbjct: 126 SDDGQSLGFGWNKYGQLGLGSAKNEVESTPLPCVVSDEVTNVACGADFTVWLSSTEGASI 185
Query: 132 XXXXXXXXXXL-----NEIESTPTKI---------PRDSLPLDELRCVQIAATDNLSAAL 177
L NE + + P+ L V++A N + A+
Sbjct: 186 LTAGLPQYGQLGHGTDNEFNMKDSSVRLAYEAQPRPKAIASLAGETIVKVACGTNHTVAV 245
Query: 178 FENGDVYAWGTFRCNEGILGF--YRDE------ITVQKTPWIIPNFSKKAKIVQMAAGKD 229
+NG VY WG G LG +DE Q+ + PN A A G
Sbjct: 246 DKNGYVYTWGF--GGYGRLGHREQKDEWAPRRIDVFQRNNVLPPNAILSAGSANSACG-- 301
Query: 230 HILFLDETGIVYAWG----NGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSF 285
G +Y WG NG + +++ S N++++ SG H F
Sbjct: 302 --------GQLYMWGKIKNNGDDWMYPKPMMDLSGW-----------NLRWMDSGSMHHF 342
Query: 286 ALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAK 345
+ D SWG Q+G+ G + S + P +V + EG+ + V+ G H++++
Sbjct: 343 -VGADSSCISWGHAQYGELGYGPNGQKSS--AAPKKVDMLEGMHVMGVACGFCHSMVIVD 399
Query: 346 SGDLYSCGRLDMFEVGISKDKLPE 369
D+ RL+ EV K L E
Sbjct: 400 RTDI--ADRLEQLEVYDGKGSLEE 421
>At5g60870 [S] KOG1426 FOG: RCC1 domain
Length = 423
Score = 82.4 bits (202), Expect = 1e-15
Identities = 96/390 (24%), Positives = 159/390 (40%), Gaps = 42/390 (10%)
Query: 43 VPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDE------------AKIVSFAA 90
V L +F WG G+ +LG G + + + P N L D+ A SF
Sbjct: 46 VTLQLFSWGRGASGQLG-GGIEEIRMYPSPVANLLFRSDQSFSLAQTPGRIDADSSSFRI 104
Query: 91 G---GMHTLALDADNNIWSWGTNDSGAL--GRDTSGAVEKLK-XXXXXXXXXXXXXXLNE 144
G G+ L D ++W WG D G L G++ S V L L
Sbjct: 105 GISCGLFHSGLTIDGDLWIWGKGDGGRLGFGQENSVFVPNLNPLFEEHSIRCIALGALGH 164
Query: 145 IESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEIT 204
T +PR + + IA + +AA+ E+G++Y WG +G LG
Sbjct: 165 KVYTRELVPRRVDDSWDCKISAIATSGTHTAAITESGELYMWGREE-GDGRLGLGPGRGP 223
Query: 205 VQKTPWIIPNFSK--KAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLR 262
+ +P+ K + ++ G + L + G ++ WG +LGR L
Sbjct: 224 NEGGGLSVPSKVKALTVPVASVSCGGFFTMALTKEGQLWNWGANSNYELGR----GDNLG 279
Query: 263 TLDPRPF-GLDNIK--YISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVP 319
+P P L+ ++ I+ G HS AL+ +GK+ SWG GQ G S+ VP
Sbjct: 280 GWEPMPVPSLEGVRITQIACGGYHSLALTEEGKVLSWGHGGHGQLGSSSLRNQ----KVP 335
Query: 320 TEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKA 379
TE+ +I +++G + + G+L+ G F++G+ LPE V
Sbjct: 336 TEIEALADKKIVFIASGGSSSAAITDGGELWMWGNAKDFQLGV--PGLPEIQTTPV---- 389
Query: 380 RSIPLPTKLEDVPSFK--AIAAGSHHSLAI 407
+ T+ ++ K +I+ G+ H+L +
Sbjct: 390 -EVNFLTEEDECQPHKVISISIGASHALCL 418
Score = 75.5 bits (184), Expect = 2e-13
Identities = 98/361 (27%), Positives = 154/361 (42%), Gaps = 59/361 (16%)
Query: 104 IWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLN-EIESTPTKIPRDSLPLDEL 162
++SWG SG LG G +E+++ + + TP +I DS
Sbjct: 50 LFSWGRGASGQLG----GGIEEIRMYPSPVANLLFRSDQSFSLAQTPGRIDADSSSF--- 102
Query: 163 RCVQIAATDNL-SAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKI 221
+I + L + L +GD++ WG + + G LGF Q+ +PN +
Sbjct: 103 ---RIGISCGLFHSGLTIDGDLWIWG--KGDGGRLGFG------QENSVFVPNLNP---- 147
Query: 222 VQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGE 281
LF + + A G + R ++ R + D + I I++
Sbjct: 148 ----------LFEEHSIRCIALGALGHKVYTRELVPRRVDDSWDCK------ISAIATSG 191
Query: 282 NHSFALSTDGKLYSWGLNQF-GQCGISTEL--EDGSLVSVPTEVILPEGVEIDSVSAGEH 338
H+ A++ G+LY WG + G+ G+ +G +SVP++V V + SVS G
Sbjct: 192 THTAAITESGELYMWGREEGDGRLGLGPGRGPNEGGGLSVPSKVKALT-VPVASVSCGGF 250
Query: 339 HTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIA 398
T+ L K G L++ G +E+G D G +P+P+ LE V IA
Sbjct: 251 FTMALTKEGQLWNWGANSNYELGRG----------DNLGGWEPMPVPS-LEGV-RITQIA 298
Query: 399 AGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQF 458
G +HSLA+ + G V SWG G +G S + + PT I+ A D IVFI GG
Sbjct: 299 CGGYHSLALTEEGKVLSWGHGGHGQLG-SSSLRNQKVPTEIE--ALADKKIVFIASGGSS 355
Query: 459 S 459
S
Sbjct: 356 S 356
>Hs19923519 [S] KOG1426 FOG: RCC1 domain
Length = 531
Score = 79.0 bits (193), Expect = 2e-14
Identities = 65/227 (28%), Positives = 102/227 (44%), Gaps = 29/227 (12%)
Query: 220 KIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPF-GL--DNIKY 276
K+ L++ + V+ +G LG TL P+ GL IK
Sbjct: 23 KVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTG----DNQSTLVPKKLEGLCGKKIKS 78
Query: 277 ISSGENHSFALST-DGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSA 335
+S G LST DG +Y+WG N + Q G T + + V V T +++ + VE V+
Sbjct: 79 LSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVE---VAC 135
Query: 336 GEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFK 395
G HH++ LA G++++ G + +VG G + P P K+ + K
Sbjct: 136 GSHHSMALAADGEVFAWGYNNCGQVG--------------SGSTANQPTPRKVTNCLHIK 181
Query: 396 ---AIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRI 439
IA G S+A+ NG VY WG+ +GLG +G+ + TP R+
Sbjct: 182 RVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQL-TPVRV 227
Score = 73.2 bits (178), Expect = 8e-13
Identities = 53/214 (24%), Positives = 92/214 (42%), Gaps = 22/214 (10%)
Query: 217 KKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKY 276
KK K + +G H+L E G+VYAWG+ QLG + + +
Sbjct: 74 KKIKSLSYGSGP-HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVE 132
Query: 277 ISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEID---SV 333
++ G +HS AL+ DG++++WG N GQ G GS + PT + + I +
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVG------SGSTANQPTPRKVTNCLHIKRVVGI 186
Query: 334 SAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPS 393
+ G+ ++ + +G++Y G ++G+ +G + L V
Sbjct: 187 ACGQTSSMAVLDNGEVYGWGYNGNGQLGLGN-----------NGNQLTPVRVAALHSV-C 234
Query: 394 FKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLG 427
I G H+LA+ G++Y+WG +G G
Sbjct: 235 VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTG 268
Score = 68.9 bits (167), Expect = 2e-11
Identities = 63/255 (24%), Positives = 103/255 (39%), Gaps = 43/255 (16%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWS 106
++ WG +LG G + + N L+ + +V A G H++AL AD +++
Sbjct: 96 VYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQ----VVEVACGSHHSMALAADGEVFA 151
Query: 107 WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQ 166
WG N+ G +G SG+ + TP K+ L R V
Sbjct: 152 WGYNNCGQVG---SGSTAN--------------------QPTPRKVTN---CLHIKRVVG 185
Query: 167 IAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAA 226
IA S A+ +NG+VY WG + LG +++T + + + Q+
Sbjct: 186 IACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAAL-----HSVCVNQIVC 240
Query: 227 GKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENH--- 283
G H L L + G++YAWG QLG ++ L P ++ + + H
Sbjct: 241 GYAHTLALTDEGLLYAWGANTYGQLG----TGNKNNLLSPAHIMVEKERVVEIAACHSAH 296
Query: 284 -SFALSTDGKLYSWG 297
S A + G +Y WG
Sbjct: 297 TSAAKTQGGHVYMWG 311
Score = 64.3 bits (155), Expect = 4e-10
Identities = 63/240 (26%), Positives = 101/240 (41%), Gaps = 21/240 (8%)
Query: 179 ENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETG 238
E+G VYAWG ++ G I + + N K ++V++A G H + L G
Sbjct: 92 EDGVVYAWGHNGYSQLGNGTTNQGIAPVQ---VCTNLLIK-QVVEVACGSHHSMALAADG 147
Query: 239 IVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGL 298
V+AWG Q+G + + I+ G+ S A+ +G++Y WG
Sbjct: 148 EVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGY 207
Query: 299 NQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMF 358
N GQ G+ +G+ ++ P V V ++ + G HTL L G LY+ G
Sbjct: 208 NGNGQLGLG---NNGNQLT-PVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYG 263
Query: 359 EVGI-SKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAKNGIVYSWG 417
++G +K+ L + V K R + + A +H S A + G VY WG
Sbjct: 264 QLGTGNKNNLLSPAHIMVE-KERVVEI-----------AACHSAHTSAAKTQGGHVYMWG 311
>At3g02510 [S] KOG1426 FOG: RCC1 domain
Length = 314
Score = 79.0 bits (193), Expect = 2e-14
Identities = 74/275 (26%), Positives = 117/275 (41%), Gaps = 60/275 (21%)
Query: 174 SAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILF 233
S A+ ++G ++ WG + G LG ++ E + P + + KI Q A G H L
Sbjct: 55 SLAICDDGTMFTWGWNQ--RGTLG-HQPETKTENIPSRVKALAN-VKITQAAIGGWHCLA 110
Query: 234 LDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKL 293
+D+ G YAWG +R TL GL+N++ I+ G H+ AL DG+L
Sbjct: 111 VDDQGRAYAWG------------KRMPFHTLSDL-LGLENVRLIAVGAFHNLALEEDGRL 157
Query: 294 YSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCG 353
+WG N++GQ G D S P V + + + ++AG H+ L G++Y G
Sbjct: 158 LAWGNNEYGQLGTG----DTQPTSHPVPVQGLDDLTLVDIAAGGWHSTALTDKGEVYGWG 213
Query: 354 RLDMFEVGI-SKDKLPEYTYKDV---------------HGK---------ARSIPLPTKL 388
R + +G+ DK + + V HG+ + + LP K+
Sbjct: 214 RGEHGRLGLGDNDKSSKMVPQKVNLLAEEDIIQFGRGDHGRLGYGRKVTTGQPLELPIKI 273
Query: 389 --------------EDVPSFKAIAAGSHHSLAIAK 409
E S K+IA G H+LAI +
Sbjct: 274 PPPEGSFNHTDEEEEGKWSAKSIACGGRHTLAIVE 308
Score = 66.6 bits (161), Expect = 8e-11
Identities = 58/220 (26%), Positives = 98/220 (44%), Gaps = 39/220 (17%)
Query: 244 GNGQQQQLGRRILERSR----LRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLN 299
G+G+ QLG E + L+P +++ + SG +S A+ DG +++WG N
Sbjct: 16 GSGEDGQLGIGTNEEKEWACVVEALEPY-----SVRSVVSGSRNSLAICDDGTMFTWGWN 70
Query: 300 QFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFE 359
Q G G E + ++P+ V V+I + G H L + G Y+ G+
Sbjct: 71 QRGTLGHQPETK---TENIPSRVKALANVKITQAAIGGWHCLAVDDQGRAYAWGK----- 122
Query: 360 VGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFG 419
++P +T D+ G LE+V + IA G+ H+LA+ ++G + +WG
Sbjct: 123 ------RMPFHTLSDLLG----------LENV---RLIAVGAFHNLALEEDGRLLAWGNN 163
Query: 420 ETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQFS 459
E +G +GD T + D ++V I GG S
Sbjct: 164 EYGQLG---TGDTQPTSHPVPVQGLDDLTLVDIAAGGWHS 200
Score = 57.8 bits (138), Expect = 4e-08
Identities = 76/318 (23%), Positives = 113/318 (34%), Gaps = 82/318 (25%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWS 106
+F WG LG P K + + R+ L KI A GG H LA+D ++
Sbjct: 64 MFTWGWNQRGTLGHQPETKTENIPS-RVKALA---NVKITQAAIGGWHCLAVDDQGRAYA 119
Query: 107 WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQ 166
WG + P D L L+ +R +
Sbjct: 120 WG-------------------------------------KRMPFHTLSDLLGLENVRLIA 142
Query: 167 IAATDNLSAALFENGDVYAWGTFRCNE-GILGFYRDEITVQKTPWIIPNFSKKAKIVQMA 225
+ A NL AL E+G + AWG NE G LG + T P +V +A
Sbjct: 143 VGAFHNL--ALEEDGRLLAWGN---NEYGQLGTGDTQPTSHPVP---VQGLDDLTLVDIA 194
Query: 226 AGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSF 285
AG H L + G VY WG G+ +LG ++S K + N
Sbjct: 195 AGGWHSTALTDKGEVYGWGRGEHGRLGLGDNDKSS--------------KMVPQKVN--- 237
Query: 286 ALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGV------------EIDSV 333
L + + +G G+ G ++ G + +P ++ PEG S+
Sbjct: 238 -LLAEEDIIQFGRGDHGRLGYGRKVTTGQPLELPIKIPPPEGSFNHTDEEEEGKWSAKSI 296
Query: 334 SAGEHHTLILA--KSGDL 349
+ G HTL + KS D+
Sbjct: 297 ACGGRHTLAIVEWKSDDI 314
Score = 53.1 bits (126), Expect = 9e-07
Identities = 45/157 (28%), Positives = 66/157 (41%), Gaps = 33/157 (21%)
Query: 74 LNPLLPRDEAKIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXX 133
L+ LL + +++ A G H LAL+ D + +WG N+ G LG
Sbjct: 129 LSDLLGLENVRLI--AVGAFHNLALEEDGRLLAWGNNEYGQLGTG--------------- 171
Query: 134 XXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNE 193
++ PT P LD+L V IAA S AL + G+VY WG R
Sbjct: 172 ------------DTQPTSHPVPVQGLDDLTLVDIAAGGWHSTALTDKGEVYGWG--RGEH 217
Query: 194 GILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDH 230
G LG ++ + + P + N + I+Q G DH
Sbjct: 218 GRLGLGDNDKSSKMVPQKV-NLLAEEDIIQFGRG-DH 252
>Hs7705931 [O] KOG0941 E3 ubiquitin protein ligase
Length = 1024
Score = 78.6 bits (192), Expect = 2e-14
Identities = 69/257 (26%), Positives = 122/257 (46%), Gaps = 39/257 (15%)
Query: 217 KKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPF----GLD 272
++ KI+Q+ G H L L + G ++AWG QLG + R T P+ G+
Sbjct: 136 QEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLG---VGRKFPSTTTPQIVEHLAGVP 192
Query: 273 NIKYISSGENHSFALSTDGKLYSWGLNQFGQCGIS-TELEDGSLVSVPTEVILPEGVEID 331
+ IS+GE HS ALS G +YSWG N+ GQ G+ TE +D P+ + + +++
Sbjct: 193 -LAQISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKDD-----PSLIEGLDNQKVE 246
Query: 332 SVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDV 391
V+ G H+ +L + G L++ G ++G H ++ P + ++
Sbjct: 247 FVACGGSHSALLTQDGLLFTFGAGKHGQLG--------------HNSTQNELRPCLVAEL 292
Query: 392 PSFKA--IAAGSHHSLA-IAKNGIVYSWGFGETYAVGLGPSGDDI-ETPTRIKNTA---- 443
++ IA G H+LA ++ G V+S+G G+ +G G + D + P ++ ++
Sbjct: 293 VGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQLGNGGTRDQLMPLPVKVSSSEELKL 352
Query: 444 ---TQDHSIVFIGCGGQ 457
T + ++ I G Q
Sbjct: 353 ESHTSEKELIMIAGGNQ 369
Score = 74.3 bits (181), Expect = 4e-13
Identities = 73/257 (28%), Positives = 118/257 (45%), Gaps = 28/257 (10%)
Query: 159 LDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKK 218
L E + +QI D S AL + G+++AWG + G LG R + TP I+ + +
Sbjct: 135 LQEKKIIQITCGDYHSLALSKGGELFAWG--QNLHGQLGVGR-KFPSTTTPQIVEHLA-G 190
Query: 219 AKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPF-GLDN--IK 275
+ Q++AG+ H + L +G +Y+WG + QLG E DP GLDN ++
Sbjct: 191 VPLAQISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKD----DPSLIEGLDNQKVE 246
Query: 276 YISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSA 335
+++ G +HS L+ DG L+++G + GQ G ++ + P V G + ++
Sbjct: 247 FVACGGSHSALLTQDGLLFTFGAGKHGQLGHNSTQNE----LRPCLVAELVGYRVTQIAC 302
Query: 336 GEHHTLILAKSGDLYSCGRLDMFEVGISKD-KLPEYTYKDVHGKARSIPLPTKLEDVPSF 394
G HT LA DL +F G KD +L +D + +PLP K+
Sbjct: 303 GRWHT--LAYVSDLGK-----VFSFGSGKDGQLGNGGTRD-----QLMPLPVKVSSSEEL 350
Query: 395 KAIAAGSHHSLAIAKNG 411
K + S L + G
Sbjct: 351 KLESHTSEKELIMIAGG 367
>Hs4557445 [S] KOG1426 FOG: RCC1 domain
Length = 551
Score = 78.2 bits (191), Expect = 3e-14
Identities = 93/390 (23%), Positives = 149/390 (37%), Gaps = 76/390 (19%)
Query: 45 LDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVS----FAAGGMHTLALDA 100
L +F +G + L L K +V + + L +E +++ F + G L
Sbjct: 5 LPLFSGDSGKPVQATLSSL-KMLDVGKWPIFSLCSEEELQLIRQACVFGSAGNEVLYTTV 63
Query: 101 DNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLD 160
++ I+ GTN G LG L +++ST DSL
Sbjct: 64 NDEIFVLGTNCCGCLG-------------------------LGDVQSTIEPRRLDSLNGK 98
Query: 161 ELRCVQIAATDNLSAALFENGDVYAWG--------TFRCNEGILGFYRDEITVQKTPWII 212
++ C+ + ++ A E G+V+ WG N G++ + I
Sbjct: 99 KIACLSYGSGPHIVLATTE-GEVFTWGHNAYSQLGNGTTNHGLVPCH-----------IS 146
Query: 213 PNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFG-- 270
N S K +++++A G H L L G V+AWG Q+G S + PR
Sbjct: 147 TNLSNK-QVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVG----SGSTVNQPIPRRVTGC 201
Query: 271 LDN--IKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGV 328
L N + I+ G+ A+ G++Y WG N GQ G+ + P V +G+
Sbjct: 202 LQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPT----PCRVAALQGI 257
Query: 329 EIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKL 388
+ V+ G HTL+L G +Y+ G ++G Y P P +
Sbjct: 258 RVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSY------------PTPVTV 305
Query: 389 EDVPSFKAIAAGS-HHSLAIAKNGIVYSWG 417
E + A S H S A + G VY WG
Sbjct: 306 EKDRIIEIAACHSTHTSAAKTQGGHVYMWG 335
Score = 72.4 bits (176), Expect = 1e-12
Identities = 79/313 (25%), Positives = 125/313 (39%), Gaps = 46/313 (14%)
Query: 46 DIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAG-GMHTLALDADNNI 104
+IFV GT LGLG + E +R L + KI + G G H + + +
Sbjct: 66 EIFVLGTNCCGCLGLGDVQSTIEPRR-----LDSLNGKKIACLSYGSGPHIVLATTEGEV 120
Query: 105 WSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRC 164
++WG N LG T+ P I S L +
Sbjct: 121 FTWGHNAYSQLGNGTTNH-----------------------GLVPCHI---STNLSNKQV 154
Query: 165 VQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQM 224
+++A S L +G+V+AWG N G +G Q P + + +V +
Sbjct: 155 IEVACGSYHSLVLTSDGEVFAWGYN--NSGQVG--SGSTVNQPIPRRVTGCLQNKVVVTI 210
Query: 225 AAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKY--ISSGEN 282
A G+ + + +TG VY WG QLG L S + R L I+ ++ G
Sbjct: 211 ACGQMCCMAVVDTGEVYVWGYNGNGQLG---LGNSGNQPTPCRVAALQGIRVQRVACGYA 267
Query: 283 HSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHT-L 341
H+ L+ +G++Y+WG N +GQ G + S S PT V + + I+ + HT
Sbjct: 268 HTLVLTDEGQVYAWGANSYGQLGTGNK----SNQSYPTPVTVEKDRIIEIAACHSTHTSA 323
Query: 342 ILAKSGDLYSCGR 354
+ G +Y G+
Sbjct: 324 AKTQGGHVYMWGQ 336
Score = 68.2 bits (165), Expect = 3e-11
Identities = 66/286 (23%), Positives = 117/286 (40%), Gaps = 44/286 (15%)
Query: 180 NGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKD-HILFLDETG 238
N +++ GT C G LG + T++ P + + + K KI ++ G HI+ G
Sbjct: 64 NDEIFVLGTNCC--GCLGLGDVQSTIE--PRRLDSLNGK-KIACLSYGSGPHIVLATTEG 118
Query: 239 IVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGL 298
V+ WG+ QLG + + ++ G HS L++DG++++WG
Sbjct: 119 EVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGY 178
Query: 299 NQFGQCGISTELEDGSLVSVPTEVILPEGVE-------IDSVSAGEHHTLILAKSGDLYS 351
N GQ G GS V+ P +P V + +++ G+ + + +G++Y
Sbjct: 179 NNSGQVG------SGSTVNQP----IPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYV 228
Query: 352 CGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKA--IAAGSHHSLAIAK 409
G ++G+ G + + P P ++ + + +A G H+L +
Sbjct: 229 WGYNGNGQLGL--------------GNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTD 274
Query: 410 NGIVYSWGFGETYAVGLG-PSGDDIETPTRIKNTATQDHSIVFIGC 454
G VY+WG +G G S TP T +D I C
Sbjct: 275 EGQVYAWGANSYGQLGTGNKSNQSYPTPV----TVEKDRIIEIAAC 316
Score = 62.0 bits (149), Expect = 2e-09
Identities = 52/201 (25%), Positives = 88/201 (42%), Gaps = 29/201 (14%)
Query: 263 TLDPRPFGLDNIKYIS-----SGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVS 317
T++PR N K I+ SG H +T+G++++WG N + Q G T
Sbjct: 86 TIEPRRLDSLNGKKIACLSYGSGP-HIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCH 144
Query: 318 VPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHG 377
+ T + + +E V+ G +H+L+L G++++ G + +VG G
Sbjct: 145 ISTNLSNKQVIE---VACGSYHSLVLTSDGEVFAWGYNNSGQVG--------------SG 187
Query: 378 KARSIPLPTKLEDVPSFKA---IAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIE 434
+ P+P ++ K IA G +A+ G VY WG+ +GLG SG+
Sbjct: 188 STVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQ-- 245
Query: 435 TPTRIKNTATQDHSIVFIGCG 455
PT + A Q + + CG
Sbjct: 246 -PTPCRVAALQGIRVQRVACG 265
>At3g03790 [S] KOG1426 FOG: RCC1 domain
Length = 1073
Score = 77.0 bits (188), Expect = 6e-14
Identities = 60/199 (30%), Positives = 99/199 (49%), Gaps = 19/199 (9%)
Query: 240 VYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDN--IKYISSGENHSFALSTDGKLYSWG 297
V++WGNG QLG ++ + R L IK +S+ + HS A+ST G++Y+WG
Sbjct: 144 VFSWGNGANYQLGTG---NQHVQKVPGRVDSLHGCFIKLVSAAKFHSVAISTHGEVYTWG 200
Query: 298 LNQFGQCG-ISTELEDG-SLVSVPTEVILPEGV-EIDSVSAGEHHTLILAKSGDLYSCGR 354
+ G+ G ++ G + V P +VI G + +V+A +HHT+I + GD+Y+ G
Sbjct: 201 FGRGGRLGHPEFDIHSGQAAVITPRQVISGLGSRRVKAVAAAKHHTVIATEGGDVYTWG- 259
Query: 355 LDMFEVGISKDKLPE----YTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAKN 410
E + D L E YT D R + T L+ A++A + H+ ++
Sbjct: 260 -SNRESDVVCDALVEGQLGYTSVDTQATPRKV---TSLK--AKIVAVSAANKHTAVVSDC 313
Query: 411 GIVYSWGFGETYAVGLGPS 429
G V++WG + +G G S
Sbjct: 314 GEVFTWGCNKEGQLGYGTS 332
Score = 66.2 bits (160), Expect = 1e-10
Identities = 72/265 (27%), Positives = 121/265 (45%), Gaps = 37/265 (13%)
Query: 167 IAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNF------SKKAK 220
++A S A+ +G+VY WG R G LG +I + I P S++ K
Sbjct: 180 VSAAKFHSVAISTHGEVYTWGFGR--GGRLGHPEFDIHSGQAAVITPRQVISGLGSRRVK 237
Query: 221 IVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRL--RTLDPR--PFGLDNIKY 276
V AA K H + E G VY WG+ ++ + L +L ++D + P + ++K
Sbjct: 238 AV--AAAKHHTVIATEGGDVYTWGSNRESDVVCDALVEGQLGYTSVDTQATPRKVTSLKA 295
Query: 277 ----ISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDS 332
+S+ H+ +S G++++WG N+ GQ G T + P V +G +
Sbjct: 296 KIVAVSAANKHTAVVSDCGEVFTWGCNKEGQLGYGTSNSASNYS--PRLVDYLKGKVFTA 353
Query: 333 VSAGEHHTLILAKSGDLYSCGRLDMFEVGISKD-KLPEYTYKDVHGKARSIPLPTKLEDV 391
+++ ++HTL+ L + R V IS++ K T + H + P +L
Sbjct: 354 IASSKYHTLVYTWGHRLVTPRR-----VIISRNLKKAGNTLLNFHRRR-----PLRLT-- 401
Query: 392 PSFKAIAAGSHHSLAIAKNGIVYSW 416
AIAAG HSLA+A++G + W
Sbjct: 402 ----AIAAGMVHSLALAEDGAFFYW 422
Score = 51.6 bits (122), Expect = 3e-06
Identities = 68/323 (21%), Positives = 128/323 (39%), Gaps = 73/323 (22%)
Query: 46 DIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRD------EAKIVSFAAGGMHTLALD 99
+++ WG G LG ++ + + PR ++ + AA HT+
Sbjct: 195 EVYTWGFGRGGRLGHPEF----DIHSGQAAVITPRQVISGLGSRRVKAVAAAKHHTVIAT 250
Query: 100 ADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPL 159
++++WG+N R++ + L + ++TP K+ SL
Sbjct: 251 EGGDVYTWGSN------RESDVVCDALVEGQLGYTSV-------DTQATPRKV--TSL-- 293
Query: 160 DELRCVQIAATDNLSAALFENGDVYAWGTFRCN-EGILGFYRDEITVQKTPWIIPNFSKK 218
+ + V ++A + +A + + G+V+ WG CN EG LG+ +P ++ ++ K
Sbjct: 294 -KAKIVAVSAANKHTAVVSDCGEVFTWG---CNKEGQLGYGTSNSASNYSPRLV-DYLKG 348
Query: 219 AKIVQMAAGKDHILFLDETGIVYAWG-----------NGQQQQLGRRILERSRLRTLDPR 267
+A+ K H L VY WG + ++ G +L R R L
Sbjct: 349 KVFTAIASSKYHTL-------VYTWGHRLVTPRRVIISRNLKKAGNTLLNFHRRRPL--- 398
Query: 268 PFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEG 327
+ I++G HS AL+ DG + W + L L S+ G
Sbjct: 399 -----RLTAIAAGMVHSLALAEDGAFFYW-------VSSDSNLRCQQLHSL-------HG 439
Query: 328 VEIDSVSAGEHHTLILAKSGDLY 350
+ S+SAG++ + +G++Y
Sbjct: 440 KTVVSISAGKYWASAVTSTGEVY 462
>Hs19311016_2 [S] KOG1426 FOG: RCC1 domain
Length = 649
Score = 75.1 bits (183), Expect = 2e-13
Identities = 68/308 (22%), Positives = 137/308 (44%), Gaps = 28/308 (9%)
Query: 166 QIAATDNLSAALFENGDVYAWGTFRCNEGILG-FYRDEITVQKTPWIIPNFSKKAKIVQM 224
Q+ A + A + ++Y W + + G + + P + KA I Q+
Sbjct: 43 QVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASYRQPKHVEKLQGKA-IHQV 101
Query: 225 AAGKDHILFLDETGIVYAWGN------GQQQQLGRRILERSRLRTLDPRPFGLDNIKYIS 278
+ G D + + + G +YA+G+ G + G +LE +L P ++ +S
Sbjct: 102 SCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNP-----VEQVS 156
Query: 279 SGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEH 338
G+NH L+ + ++YSWG ++G+ G+ +E ED P +V +P+ + I +V G
Sbjct: 157 CGDNHVVVLTRNKEVYSWGCGEYGRLGLDSE-ED---YYTPQKVDVPKALIIVAVQCGCD 212
Query: 339 HTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPT-----KLEDVPS 393
T +L +SG + +CG + ++G+++ ++ H +P T K
Sbjct: 213 GTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYH----EVPYTTSFTLAKQLSFYK 268
Query: 394 FKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIG 453
+ IA G H+ AI + G + ++G + +G+G + + ++ +
Sbjct: 269 IRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRL--GINLLGGPLGGKQVIRVS 326
Query: 454 CGGQFSIS 461
CG +F+I+
Sbjct: 327 CGDEFTIA 334
>7300793 [S] KOG1426 FOG: RCC1 domain
Length = 484
Score = 68.9 bits (167), Expect = 2e-11
Identities = 61/238 (25%), Positives = 97/238 (40%), Gaps = 41/238 (17%)
Query: 191 CNEGILGFYRDEITVQKTPWIIPNFSKKA-KIVQMAAGKDHILFLDETGIVYAWGNGQQQ 249
C I E V P + FS++ ++ Q+ G +H + L+ G V+ WGNG +
Sbjct: 145 CGSHINVAISSENCVYSIPSCLHQFSERQFRVKQLQCGHEHAVLLNANGDVFTWGNGLRG 204
Query: 250 QLGRRILERSRLRTLDPRPFGLD-------------------NIKYISSGENHSFALSTD 290
QLG L L G+ I I++G HS A+S
Sbjct: 205 QLGLAELRVEETPQLLEALAGIKVYIYLTCPLILSVTHSSALQITQIAAGGWHSAAISAF 264
Query: 291 GKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDS-----------------V 333
G LY+WGLN GQ G+ ++ G ++ PT LP+ ++ V
Sbjct: 265 GDLYTWGLNCSGQLGLRV-MKPGGVLKEPTVFPLPQLQDLPECACSQSGESNDDCAPLRV 323
Query: 334 SAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDV 391
AG HTL++ + G L+ G ++G +L + +Y D I + ++DV
Sbjct: 324 FAGSRHTLLIRRCGRLWVSGWCKHGQLG---RQLQDLSYVDAFQALEGITMNPTVDDV 378
>CE07026 [S] KOG1426 FOG: RCC1 domain
Length = 1098
Score = 68.2 bits (165), Expect = 3e-11
Identities = 72/304 (23%), Positives = 113/304 (36%), Gaps = 71/304 (23%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIWS 106
++ +G G +LG G + ++ R+N L+ K+ A G HT+ L +
Sbjct: 554 LWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLI----CKVTQIACGRAHTVVLTDTGRVLV 609
Query: 107 WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQ 166
G+ G +G D ++K+ TP LPL LR
Sbjct: 610 CGSGSYGQMGVDDD--IKKV------------------FAFTP-------LPLGPLRVRD 642
Query: 167 IAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEI-----------------TVQKTP 209
IA S + E+ V+ WG + F +I T TP
Sbjct: 643 IATHYYHSICITEDNRVFEWGRNPQELKMRMFVMKKIRSAQLKNTEDPSSPSPSTNGSTP 702
Query: 210 WIIPNFSKK----------------AKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGR 253
+ N + IV +A G H + G +Y WG G QLG
Sbjct: 703 RVNLNLPAEIPREDLGLREVKHFLDGNIVSVACGLSHSALITSEGTLYTWGKGLDYQLGH 762
Query: 254 RILERSRLRTLDPRP-FGLDNIKYI--SSGENHSFALSTDGKLYSWGLNQFGQCGISTEL 310
++ ++P F + K++ S G NH+ A + DG +++WG N FGQCG+ T+
Sbjct: 763 G----NKNERMEPHQVFEPNGAKWVNVSLGNNHTIASTDDGSVFAWGKNDFGQCGVLTKK 818
Query: 311 EDGS 314
S
Sbjct: 819 NGNS 822
Score = 67.8 bits (164), Expect = 3e-11
Identities = 49/195 (25%), Positives = 88/195 (45%), Gaps = 19/195 (9%)
Query: 224 MAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENH 283
+A G +HIL L +G + AWG + Q G + R+ L I+ I+ G+ H
Sbjct: 487 IACGAEHILVLSSSGQLSAWGGNRFGQCG--VGHSFRIANLHQVDGDWPAIEKIACGQFH 544
Query: 284 SFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLIL 343
S + +DG L+++G +GQ G LV ++ ++ ++ G HT++L
Sbjct: 545 SAFICSDGSLWTFGWGVWGQLGHGGRNNSNQLVPTRVNGLI---CKVTQIACGRAHTVVL 601
Query: 344 AKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPL-PTKLEDVPSFKAIAAGSH 402
+G + CG ++G+ D + + +PL P ++ D IA +
Sbjct: 602 TDTGRVLVCGSGSYGQMGVDDDIKKVFAF-------TPLPLGPLRVRD------IATHYY 648
Query: 403 HSLAIAKNGIVYSWG 417
HS+ I ++ V+ WG
Sbjct: 649 HSICITEDNRVFEWG 663
Score = 59.3 bits (142), Expect = 1e-08
Identities = 87/428 (20%), Positives = 159/428 (36%), Gaps = 106/428 (24%)
Query: 47 IFVWGTGSMCELGLGPLAKNKEVKR--------PRLNPLLPRDEAKIV-----------S 87
+ +WG + + + N + KR P L P P+ E + +
Sbjct: 427 LMIWGNFTNAQQRMEMPQMNAKSKRSDSVTNGAPTLPPPAPKPEQHLPRVLEYPGGRPRA 486
Query: 88 FAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIES 147
A G H L L + + +WG N G G S + L
Sbjct: 487 IACGAEHILVLSSSGQLSAWGGNRFGQCGVGHSFRIANLH-------------------- 526
Query: 148 TPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDV--YAWGTFRCNEGILGFYRDEITV 205
++ D ++++ C Q SA + +G + + WG + G LG +
Sbjct: 527 ---QVDGDWPAIEKIACGQFH-----SAFICSDGSLWTFGWGVW----GQLGHGGRNNSN 574
Query: 206 QKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLD 265
Q P + K+ Q+A G+ H + L +TG V G+G Q+G + ++
Sbjct: 575 QLVPTRVNGLI--CKVTQIACGRAHTVVLTDTGRVLVCGSGSYGQMGVDD-DIKKVFAFT 631
Query: 266 PRPFGLDNIKYISSGENHSFALSTDGKLYSWGLN-------QFGQCGI-STELEDGSLVS 317
P P G ++ I++ HS ++ D +++ WG N F I S +L++ S
Sbjct: 632 PLPLGPLRVRDIATHYYHSICITEDNRVFEWGRNPQELKMRMFVMKKIRSAQLKNTEDPS 691
Query: 318 VPT----------EVILPEGV----------------EIDSVSAGEHHTLILAKSGDLYS 351
P+ + LP + I SV+ G H+ ++ G LY+
Sbjct: 692 SPSPSTNGSTPRVNLNLPAEIPREDLGLREVKHFLDGNIVSVACGLSHSALITSEGTLYT 751
Query: 352 CGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFK--AIAAGSHHSLAIAK 409
G+ +++G HG P ++ + K ++ G++H++A
Sbjct: 752 WGKGLDYQLG--------------HGNKNERMEPHQVFEPNGAKWVNVSLGNNHTIASTD 797
Query: 410 NGIVYSWG 417
+G V++WG
Sbjct: 798 DGSVFAWG 805
Score = 50.4 bits (119), Expect = 6e-06
Identities = 47/187 (25%), Positives = 79/187 (42%), Gaps = 36/187 (19%)
Query: 277 ISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAG 336
I+ G H LS+ G+L +WG N+FGQCG+ +L V + I+ ++ G
Sbjct: 487 IACGAEHILVLSSSGQLSAWGGNRFGQCGVGHSFRIANLHQVD-----GDWPAIEKIACG 541
Query: 337 EHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIP--LPTKLED-VPS 393
+ H+ + G L++ G ++G HG + +PT++ +
Sbjct: 542 QFHSAFICSDGSLWTFGWGVWGQLG--------------HGGRNNSNQLVPTRVNGLICK 587
Query: 394 FKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIET----------PTRIKNTA 443
IA G H++ + G V G G +G+ DDI+ P R+++ A
Sbjct: 588 VTQIACGRAHTVVLTDTGRVLVCGSGSYGQMGV---DDDIKKVFAFTPLPLGPLRVRDIA 644
Query: 444 TQ-DHSI 449
T HSI
Sbjct: 645 THYYHSI 651
>At3g15430 [S] KOG1426 FOG: RCC1 domain
Length = 488
Score = 67.8 bits (164), Expect = 3e-11
Identities = 71/281 (25%), Positives = 116/281 (41%), Gaps = 34/281 (12%)
Query: 169 ATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGK 228
AT L N VY+ G G+L + T Q + F A++ Q++A +
Sbjct: 117 ATGKYHTLLINNSKVYSCGVSL--SGVLAHGSE--TTQCVAFTPIEFPFPAQVAQVSATQ 172
Query: 229 DHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALS 288
+H F+ ++G V G+ G R R K +++G + + LS
Sbjct: 173 NHSAFVLQSGQVLTCGDNSSHCCGHLDTSRPIFRPKLVEALKGTPCKQVAAGLHFTVFLS 232
Query: 289 TDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGV-EIDSVSAGEHHTLILAKSG 347
+G Y+ G N GQ G L+ VP V + + + ++AG + L + + G
Sbjct: 233 REGHAYTCGSNTHGQLGHGDTLDR----PVPKVVEFLKTIGPVVQIAAGPSYVLAVTQDG 288
Query: 348 DLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKA-------IAAG 400
+YS G F +G HG+ + P ++ +FK ++AG
Sbjct: 289 SVYSFGSGSNFCLG--------------HGEQQDELQPRVIQ---AFKRKGIHILRVSAG 331
Query: 401 SHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKN 441
H++A+ NG VY+WG G A+G G D I TP + N
Sbjct: 332 DEHAVALDSNGRVYTWGKGYCGALGHGDENDKI-TPQVLVN 371
Score = 64.3 bits (155), Expect = 4e-10
Identities = 81/311 (26%), Positives = 133/311 (42%), Gaps = 53/311 (17%)
Query: 61 GPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMH-TLALDADNNIWSWGTNDSGALGR-D 118
G L ++ + RP+L L K V A G+H T+ L + + ++ G+N G LG D
Sbjct: 196 GHLDTSRPIFRPKLVEALKGTPCKQV---AAGLHFTVFLSREGHAYTCGSNTHGQLGHGD 252
Query: 119 T-SGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAAL 177
T V K+ +E T P VQIAA + A+
Sbjct: 253 TLDRPVPKV------------------VEFLKTIGP----------VVQIAAGPSYVLAV 284
Query: 178 FENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKA-KIVQMAAGKDHILFLDE 236
++G VY++G+ + LG + +Q P +I F +K I++++AG +H + LD
Sbjct: 285 TQDGSVYSFGS--GSNFCLGHGEQQDELQ--PRVIQAFKRKGIHILRVSAGDEHAVALDS 340
Query: 237 TGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIK-----YISSGENHSFALSTDG 291
G VY WG G LG E ++ P L N+ + + + +F L G
Sbjct: 341 NGRVYTWGKGYCGALGHGD-ENDKI-----TPQVLVNLNNCLAVQVCARKRKTFVLVEGG 394
Query: 292 KLYSWGLNQFGQCGISTE-LEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLY 350
LY +G FG G + D L E + P + VS G +HT+++ + G ++
Sbjct: 395 LLYGFGWMGFGSLGFPDRGVSDKVLRPRVLECLKPH--RVSQVSTGLYHTIVVTQRGRIF 452
Query: 351 SCGRLDMFEVG 361
G + ++G
Sbjct: 453 GFGDNERAQLG 463
>7297063 [S] KOG1427 Uncharacterized conserved protein contains RCC1 domain
Length = 487
Score = 67.4 bits (163), Expect = 5e-11
Identities = 70/275 (25%), Positives = 116/275 (41%), Gaps = 41/275 (14%)
Query: 167 IAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAA 226
+A+ + + + N D A G R G LG +D I + + P IIP ++ IVQ A
Sbjct: 119 VASGPSAAHTILINMDRKALGFGRNPSGQLGLSQD-IKLAEKPTIIPAL-EQLNIVQAAV 176
Query: 227 GKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDN--IKYISSGENHS 284
G+ H LFL +TG VYA G + Q G + + P P I I G S
Sbjct: 177 GRHHTLFLTDTGTVYACGENKSGQCG---VGNTHANIYSPTPINYRGPPIIRIGCGAEFS 233
Query: 285 FALSTDGKLYSWGLNQFGQCGISTELE--------DGSLVSVPTEVIL------------ 324
L G L+++GL ++GQ G +T+ + + P +V+L
Sbjct: 234 VILDIKGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTP 293
Query: 325 PEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPL 384
+GV+I + G +HT+ + +YS G +G ++ K +P
Sbjct: 294 VDGVQIVDFACGNNHTVAIDSKKRVYSWGFGGFGRLGHAEP------------KDEMVPR 341
Query: 385 PTKLEDVP--SFKAIAAGSHHSLAIAKNGIVYSWG 417
K D +++ GS SL + + G+++ +G
Sbjct: 342 LMKFFDTQGRGGRSVFCGSTFSLIVNELGLLFLFG 376
Score = 57.4 bits (137), Expect = 5e-08
Identities = 62/264 (23%), Positives = 105/264 (39%), Gaps = 33/264 (12%)
Query: 217 KKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLG-RRILERSRLRTLDPRPFGLDNIK 275
+K + V H + ++ +G QLG + ++ + T+ P L NI
Sbjct: 114 EKYRYVASGPSAAHTILINMDRKALGFGRNPSGQLGLSQDIKLAEKPTIIPALEQL-NIV 172
Query: 276 YISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSA 335
+ G +H+ L+ G +Y+ G N+ GQCG+ + + PT + G I +
Sbjct: 173 QAAVGRHHTLFLTDTGTVYACGENKSGQCGVGNTHAN---IYSPTPINY-RGPPIIRIGC 228
Query: 336 GEHHTLILAKSGDLYSCGRLDMFEVGISKD-------------------KLPEYTYKDVH 376
G ++IL G L++ G + ++G + D K+ Y K
Sbjct: 229 GAEFSVILDIKGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKE 288
Query: 377 GKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETP 436
G + D A G++H++AI VYSWGFG +G D++ P
Sbjct: 289 GHVTPV-------DGVQIVDFACGNNHTVAIDSKKRVYSWGFGGFGRLGHAEPKDEM-VP 340
Query: 437 TRIKNTATQDHSIVFIGCGGQFSI 460
+K TQ + CG FS+
Sbjct: 341 RLMKFFDTQGRGGRSVFCGSTFSL 364
Score = 52.4 bits (124), Expect = 2e-06
Identities = 85/394 (21%), Positives = 152/394 (38%), Gaps = 88/394 (22%)
Query: 65 KNKEVKRPRLNPLLPRDEAKIVSFAAG--GMHTLALDADNNIWSWGTNDSGALGRDTSGA 122
KN RP L E K A+G HT+ ++ D +G N SG LG
Sbjct: 96 KNVTKVRPNLYSFHRFTEEKYRYVASGPSAAHTILINMDRKALGFGRNPSGQLGLSQD-- 153
Query: 123 VEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGD 182
++ PT IP L++L VQ A + + L + G
Sbjct: 154 --------------------IKLAEKPTIIP----ALEQLNIVQAAVGRHHTLFLTDTGT 189
Query: 183 VYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYA 242
VYA G + + +G I TP N+ + I+++ G + + LD G ++
Sbjct: 190 VYACGENKSGQCGVGNTHANI-YSPTP---INY-RGPPIIRIGCGAEFSVILDIKGSLHT 244
Query: 243 WGNGQQQQLGRR-------------------------ILERSRLRTLDPRPFGLDNIKYI 277
+G + QLG +E+S+ + P +D ++ +
Sbjct: 245 FGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTP----VDGVQIV 300
Query: 278 --SSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSA 335
+ G NH+ A+ + ++YSWG FG+ G + ++ +V + +G SV
Sbjct: 301 DFACGNNHTVAIDSKKRVYSWGFGGFGRLGHAEPKDE--MVPRLMKFFDTQGRGGRSVFC 358
Query: 336 GEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFK 395
G +LI+ + G L+ G+ G+A P P ++D+ +
Sbjct: 359 GSTFSLIVNELGLLFLFGQ------------------NKKTGEANMYPKP--VQDLSGWN 398
Query: 396 AIAAG-SHHSLAIAKNGIVYSWGFGETYA-VGLG 427
G ++ S+ I+ + + +WG T+ +G+G
Sbjct: 399 ITDIGCANTSIMISADDTLIAWGASPTFGELGIG 432
Score = 49.7 bits (117), Expect = 1e-05
Identities = 71/297 (23%), Positives = 120/297 (39%), Gaps = 39/297 (13%)
Query: 85 IVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGA----VEKLKXXXXXXXXXXXXX 140
I+ G ++ LD ++ ++G + G LG +T KL
Sbjct: 223 IIRIGCGAEFSVILDIKGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLY 282
Query: 141 XLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYR 200
E T P+D ++ V A +N + A+ VY+WG G LG
Sbjct: 283 IEKSKEGHVT-------PVDGVQIVDFACGNNHTVAIDSKKRVYSWGF--GGFGRLG--H 331
Query: 201 DEITVQKTPWIIPNFSKKAKIVQ-MAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERS 259
E + P ++ F + + + + G L ++E G+++ + GQ ++ G +
Sbjct: 332 AEPKDEMVPRLMKFFDTQGRGGRSVFCGSTFSLIVNELGLLFLF--GQNKKTGEANMYPK 389
Query: 260 RLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLN-QFGQCGISTELEDGSLVSV 318
++ L NI I N S +S D L +WG + FG+ GI E + S +V
Sbjct: 390 PVQDLSGW-----NITDIGCA-NTSIMISADDTLIAWGASPTFGELGIG-EFQKSS--TV 440
Query: 319 PTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISK-DKLPEYTYKD 374
P EV + ++I V+ G HT++L + E K +K+PEYT D
Sbjct: 441 PKEVPKLDNIKIPQVTMGYSHTVLLVDT----------THEATKQKYEKMPEYTIDD 487
>7301213 [R] KOG0589 Serine/threonine protein kinase
Length = 841
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/163 (28%), Positives = 75/163 (45%), Gaps = 15/163 (9%)
Query: 277 ISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAG 336
++ ++H ++ DG Y+WG GQ G+ T LE + P+ + + S AG
Sbjct: 457 VAMSDSHFVVVNEDGSAYAWGEGTHGQLGL-TALE--AWKHYPSRMESVRNYHVVSACAG 513
Query: 337 EHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKA 396
+ T+++ ++G L SCG +G +D S L +L DV +
Sbjct: 514 DGFTILVTQAGSLLSCGSNAHLALG-----------QDEQRNYHSPKLIARLADV-RVEQ 561
Query: 397 IAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRI 439
+AAG H LA+++ G VY WG A+GLG + P +I
Sbjct: 562 VAAGLQHVLALSREGAVYVWGTSTCGALGLGNYQQQQKFPQKI 604
Score = 55.8 bits (133), Expect = 1e-07
Identities = 63/301 (20%), Positives = 122/301 (39%), Gaps = 34/301 (11%)
Query: 165 VQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAK---I 221
V +A +D+ + E+G YAWG G LG +T + P+ + + +
Sbjct: 455 VDVAMSDSHFVVVNEDGSAYAWG--EGTHGQLG-----LTALEAWKHYPSRMESVRNYHV 507
Query: 222 VQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGE 281
V AG + + + G + + G+ LG+ L R + ++ +++G
Sbjct: 508 VSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQRNYHSPKLIARLADV-RVEQVAAGL 566
Query: 282 NHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPE-GVEIDSVSAGEHHT 340
H ALS +G +Y WG + G G+ + P +++L + + G +
Sbjct: 567 QHVLALSREGAVYVWGTSTCGALGLGNYQQQQKF---PQKILLSHVKTKPSKIYCGPDTS 623
Query: 341 LILAKSGDLYSCGRLDMFEVGISKD-KLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAA 399
+L +G+L+ CG D ++G + K+ + + + LP K+
Sbjct: 624 AVLFANGELHVCGSNDYNKLGFQRSAKITAF---------KKVQLPHKVTQA------CF 668
Query: 400 GSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFIGCGGQFS 459
S HS+ + + G VY+ G G+ + ++ PT + + + IV C Q +
Sbjct: 669 SSTHSVFLVEGGYVYTMGRNAEGQRGIRHC-NSVDHPTLV--DSVKSRYIVKANCSDQCT 725
Query: 460 I 460
I
Sbjct: 726 I 726
Score = 53.9 bits (128), Expect = 5e-07
Identities = 62/238 (26%), Positives = 92/238 (38%), Gaps = 41/238 (17%)
Query: 18 LHSTLNHKFVSINSQDDYKHLYRSVVPLDIFVWGTGSMCELGLGPLAKNKEVKRPRLNPL 77
+ S N+ VS + D + L L GS L LG + + P+L
Sbjct: 499 MESVRNYHVVSACAGDGFTILVTQAGSL----LSCGSNAHLALGQ-DEQRNYHSPKLIAR 553
Query: 78 LPRDEAKIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXX 137
L + ++ AAG H LAL + ++ WGT+ GALG +K
Sbjct: 554 LA--DVRVEQVAAGLQHVLALSREGAVYVWGTSTCGALGLGNYQQQQKFP---------- 601
Query: 138 XXXXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILG 197
L+ +++ P+K I + SA LF NG+++ G+ N+ LG
Sbjct: 602 QKILLSHVKTKPSK---------------IYCGPDTSAVLFANGELHVCGSNDYNK--LG 644
Query: 198 FYRD-EITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRR 254
F R +IT K K+ Q H +FL E G VY G + Q G R
Sbjct: 645 FQRSAKITAFK------KVQLPHKVTQACFSSTHSVFLVEGGYVYTMGRNAEGQRGIR 696
Score = 52.0 bits (123), Expect = 2e-06
Identities = 42/147 (28%), Positives = 64/147 (42%), Gaps = 13/147 (8%)
Query: 218 KAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYI 277
KA IV +A H + ++E G YAWG G QLG LE + R + N +
Sbjct: 451 KAVIVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGLTALE--AWKHYPSRMESVRNYHVV 508
Query: 278 S--SGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSA 335
S +G+ + ++ G L S G N G + S P + V ++ V+A
Sbjct: 509 SACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQRNYHS----PKLIARLADVRVEQVAA 564
Query: 336 GEHHTLILAKSGDLY-----SCGRLDM 357
G H L L++ G +Y +CG L +
Sbjct: 565 GLQHVLALSREGAVYVWGTSTCGALGL 591
>At3g26100 [S] KOG1426 FOG: RCC1 domain
Length = 532
Score = 63.9 bits (154), Expect = 5e-10
Identities = 78/351 (22%), Positives = 142/351 (40%), Gaps = 57/351 (16%)
Query: 90 AGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTP 149
AG H++A+ + ++++G N+SG LG G E +E P
Sbjct: 150 AGPGHSVAVTSKGEVYTFGYNNSGQLGH---GHTE------------------DEARIQP 188
Query: 150 TKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTP 209
+ L +R +Q AA + + ++G VYA G E G + TP
Sbjct: 189 VR------SLQGVRIIQAAAGAARTMLISDDGKVYACGKESFGEAEYGGQGTKPVT--TP 240
Query: 210 WIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPF 269
++ + K +VQ A G L G VY + G +LG + + ++PRP
Sbjct: 241 QLVTSL-KNIFVVQAAIGNYFTAVLSREGKVYTFSWGNDGRLGHQ----TEAADVEPRPL 295
Query: 270 --GLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPE- 326
L+N+ + + + L+ + + G CG+ +L GS ++ +
Sbjct: 296 LGPLENVPVVQIAAGYCYLLALACQPNGMSVYSVG-CGLGGKLGHGSRTDEKYPRVIEQF 354
Query: 327 ---GVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIP 383
++ V+AG H ++ + G + + G +G HG
Sbjct: 355 QILNLQPRVVAAGAWHAAVVGQDGRVCTWGWGRYGCLG--------------HGNEECES 400
Query: 384 LPTKLEDVPSFKAI--AAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDD 432
+P +E + KA+ A G + + ++ +G VYS+G GE+ ++G PS D+
Sbjct: 401 VPKVVEGLSHVKAVHVATGDYTTFVVSDDGDVYSFGCGESASLGHHPSFDE 451
Score = 55.8 bits (133), Expect = 1e-07
Identities = 40/157 (25%), Positives = 77/157 (48%), Gaps = 16/157 (10%)
Query: 279 SGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEH 338
+G HS A+++ G++Y++G N GQ G ++ + V + +GV I +AG
Sbjct: 150 AGPGHSVAVTSKGEVYTFGYNNSGQLGHGHTEDEARIQPVRS----LQGVRIIQAAAGAA 205
Query: 339 HTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIP-LPTKLEDVPSFKAI 397
T++++ G +Y+CG K+ E Y K + P L T L+++ +A
Sbjct: 206 RTMLISDDGKVYACG----------KESFGEAEYGGQGTKPVTTPQLVTSLKNIFVVQA- 254
Query: 398 AAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIE 434
A G++ + +++ G VY++ +G +G D+E
Sbjct: 255 AIGNYFTAVLSREGKVYTFSWGNDGRLGHQTEAADVE 291
Score = 53.5 bits (127), Expect = 7e-07
Identities = 82/390 (21%), Positives = 141/390 (36%), Gaps = 105/390 (26%)
Query: 46 DIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPRDEAKIVSFAAGGMHTLALDADNNIW 105
+++ +G + +LG G R+ P+ +I+ AAG T+ + D ++
Sbjct: 163 EVYTFGYNNSGQLGHGHTEDEA-----RIQPVRSLQGVRIIQAAAGAARTMLISDDGKVY 217
Query: 106 SWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELRCV 165
+ G G G + P P+ L + V
Sbjct: 218 ACGKESFGEAEYGGQG-------------------------TKPVTTPQLVTSLKNIFVV 252
Query: 166 QIAATDNLSAALFENGDVY--AWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKAKIVQ 223
Q A + +A L G VY +WG N+G LG + V+ P + P + +VQ
Sbjct: 253 QAAIGNYFTAVLSREGKVYTFSWG----NDGRLGHQTEAADVEPRPLLGP--LENVPVVQ 306
Query: 224 MAAGKDHILFL--DETGI-VYAWGNGQQQQLGR---------RILERSRLRTLDPRPF-- 269
+AAG ++L L G+ VY+ G G +LG R++E+ ++ L PR
Sbjct: 307 IAAGYCYLLALACQPNGMSVYSVGCGLGGKLGHGSRTDEKYPRVIEQFQILNLQPRVVAA 366
Query: 270 ----------------------------------------GLDNIK--YISSGENHSFAL 287
GL ++K ++++G+ +F +
Sbjct: 367 GAWHAAVVGQDGRVCTWGWGRYGCLGHGNEECESVPKVVEGLSHVKAVHVATGDYTTFVV 426
Query: 288 STDGKLYSWGLNQFGQCGISTELEDG----SLVSVPTEVILPEGVEIDSVSAG------- 336
S DG +YS+G + G ++ + V PT V + V V
Sbjct: 427 SDDGDVYSFGCGESASLGHHPSFDEQGNRHANVLSPTVVTSLKQVNERMVQISLTNSIYW 486
Query: 337 EHHTLILAKSGDLYSCGRLDMFEVGISKDK 366
HT L +SG L++ G D ++G K
Sbjct: 487 NAHTFALTESGKLFAFGAGDQGQLGTELGK 516
Score = 50.8 bits (120), Expect = 4e-06
Identities = 59/213 (27%), Positives = 90/213 (41%), Gaps = 17/213 (7%)
Query: 223 QMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGEN 282
Q AG H + + G VY +G QLG E R R I ++G
Sbjct: 147 QAVAGPGHSVAVTSKGEVYTFGYNNSGQLGHGHTE-DEARIQPVRSLQGVRIIQAAAGAA 205
Query: 283 HSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLI 342
+ +S DGK+Y+ G FG+ + V+ P V + + + + G + T +
Sbjct: 206 RTMLISDDGKVYACGKESFGEAEYGG--QGTKPVTTPQLVTSLKNIFVVQAAIGNYFTAV 263
Query: 343 LAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSH 402
L++ G +Y+ F G + DV + PL LE+VP + IAAG
Sbjct: 264 LSREGKVYT------FSWGNDGRLGHQTEAADVEPR----PLLGPLENVPVVQ-IAAGYC 312
Query: 403 HSLAIA--KNGI-VYSWGFGETYAVGLGPSGDD 432
+ LA+A NG+ VYS G G +G G D+
Sbjct: 313 YLLALACQPNGMSVYSVGCGLGGKLGHGSRTDE 345
>At5g11580 [S] KOG1426 FOG: RCC1 domain
Length = 541
Score = 62.8 bits (151), Expect = 1e-09
Identities = 102/427 (23%), Positives = 169/427 (38%), Gaps = 80/427 (18%)
Query: 68 EVKRPRLNPLLPRD-EAKIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRD-------- 118
E K P L L+ D KI+S AAG HT+AL D ++SWG G LG
Sbjct: 2 EDKSPTL--LISEDLSRKIISLAAGEAHTIALTGDGCVYSWGRGMFGRLGTGKESDELVP 59
Query: 119 -------------------TSGAVEKLKXXXXXXXXXXXXXX-------LNEIESTPTKI 152
+GA L L E E++ + +
Sbjct: 60 VLVEFPNQAEGDRIRIVGVAAGAYHSLAVSDGQLGFDGENSLAPCLIKNLFERETSSSSL 119
Query: 153 PRDSLPL-DELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQKTPWI 211
+ +L+ + A +S A+ G ++ WG + R T P+
Sbjct: 120 NDSGREVGSDLKVCTVKAGSMMSLAIDNVGGLWMWGNVPPQDSEPD-PRLSFTSIPIPFP 178
Query: 212 IPNFSKKAKIVQMAAGKDHILFLDETG-----------IVYAWGNGQQQQLGRRILE-RS 259
I +F + ++++A G +H++ L G ++Y+WGN QLG E R+
Sbjct: 179 ILDFHGRT-VLKVACGDEHVVALVGPGDIHKDNSYDVSVLYSWGNNHHGQLGLGDGESRA 237
Query: 260 RLRTLDP--RPFGLDNIKYISSGENHSFALS-----TDGKLYSW--GLNQFGQCGISTEL 310
R +T++ + GL + I+ G +H+ L+ G W G + GQ G +
Sbjct: 238 RPQTVETFNQKSGL-TVYDIACGAHHTALLTYRKETPKGPSICWTFGFGENGQLGHRSNK 296
Query: 311 EDGSLVSVPTEVI-LPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPE 369
S+P V LPE + SV G HT +++ G ++S G E G+ P+
Sbjct: 297 SS----SLPEPVSDLPEHAYLVSVDCGLFHTSVVSSEGYVWSWG----MERGLG--LCPD 346
Query: 370 YTYKDVHGKARSIPLPTKLEDVPS-FK---AIAAGSHHSLAIAKNGI-VYSWGFGETYAV 424
+ +V S+ P K+ S F+ ++ G+ H++ + G ++SWG G +
Sbjct: 347 VNFTEVEAGDDSV--PRKISGGSSRFRDPVQVSCGAAHTVLVVDGGYKLWSWGRGRNGVL 404
Query: 425 GLGPSGD 431
G G D
Sbjct: 405 GTGNVSD 411
Score = 61.6 bits (148), Expect = 2e-09
Identities = 70/271 (25%), Positives = 112/271 (40%), Gaps = 37/271 (13%)
Query: 207 KTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQL--GRRILERSRLRTL 264
K+P ++ + KI+ +AAG+ H + L G VY+WG G +L G+ E +
Sbjct: 4 KSPTLLISEDLSRKIISLAAGEAHTIALTGDGCVYSWGRGMFGRLGTGKESDELVPVLVE 63
Query: 265 DPRPFGLDNIKY--ISSGENHSFALSTDGKLYSWGLNQFGQCGIST----ELEDGSLVSV 318
P D I+ +++G HS A+S DG+L G N C I E SL
Sbjct: 64 FPNQAEGDRIRIVGVAAGAYHSLAVS-DGQLGFDGENSLAPCLIKNLFERETSSSSLNDS 122
Query: 319 PTEVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGK 378
EV +++ +V AG +L + G L+ G + P+ + D
Sbjct: 123 GREV--GSDLKVCTVKAGSMMSLAIDNVGGLWMWGNVP-----------PQDSEPDPRLS 169
Query: 379 ARSIPLPTKLEDV--PSFKAIAAGSHHSLAIAKNG-----------IVYSWGFGETYAVG 425
SIP+P + D + +A G H +A+ G ++YSWG +G
Sbjct: 170 FTSIPIPFPILDFHGRTVLKVACGDEHVVALVGPGDIHKDNSYDVSVLYSWGNNHHGQLG 229
Query: 426 LGPSGDDIETPTRIKNTATQDHSIVF-IGCG 455
LG G+ P ++ + V+ I CG
Sbjct: 230 LG-DGESRARPQTVETFNQKSGLTVYDIACG 259
>Hs13540582 [S] KOG1426 FOG: RCC1 domain
Length = 464
Score = 61.6 bits (148), Expect = 2e-09
Identities = 103/434 (23%), Positives = 169/434 (38%), Gaps = 67/434 (15%)
Query: 47 IFVWGTGSMCELGL--------GPLAKNKEVKRPRLNPLLPRDEA--KIVSFAAGGMHTL 96
+FVWG LG+ GP + R R+ P+ R E KI S A G TL
Sbjct: 61 VFVWGFSFSGALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTL 120
Query: 97 --ALDAD-NNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIP 153
+ AD +W G N LG S +K + +E +P +P
Sbjct: 121 LSSKTADVTKVWGMGLNKDSQLGFHRSRK-DKTRGYEYV------------LEPSPVSLP 167
Query: 154 RDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTF---RCNEGILG--FYRDEITVQKT 208
D E R +Q++ S L + V++ G +C ++ Y + V +
Sbjct: 168 LDRP--QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHR- 224
Query: 209 PWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYA--WGNGQQQQLGRRILERSRLRTLDP 266
+ +F ++VQ+A G+DH LFL + G VY+ WG Q LG + T P
Sbjct: 225 ---MQDFD--GQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNI------TSSP 273
Query: 267 RPFGLD----NIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEV 322
G D N+ +++ + A+S DG L+ WG +++ Q T D + V+VP +
Sbjct: 274 TKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVT---DSTQVNVPRCL 330
Query: 323 ILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFE-VGISKDKLPEYTYKDVHGKARS 381
++ + G +L G ++ G + + + + +PE + G
Sbjct: 331 HFSGVGKVRQAACGGTGCAVLNGEGHVFVWGYGILGKGPNLVESAVPEMIPPTLFGL--- 387
Query: 382 IPLPTKLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKN 441
T+ I G H A+ G ++ WG +G+G +D P R+
Sbjct: 388 ----TEFNPEIQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRL-EDQYFPWRV-- 440
Query: 442 TATQDHSIVFIGCG 455
T V + CG
Sbjct: 441 --TMPGEPVDVACG 452
>Hs22049475 [S] KOG1426 FOG: RCC1 domain
Length = 267
Score = 60.8 bits (146), Expect = 4e-09
Identities = 72/273 (26%), Positives = 109/273 (39%), Gaps = 47/273 (17%)
Query: 82 EAKIVSFAAGGMHTLALDADNNIWS--WGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXX 139
+ ++V A G H+L L ++S WG + LG
Sbjct: 32 DGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGH---------------------- 69
Query: 140 XXLNEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFY 199
I S+PTK+ D L + +Q+A + A+ +G ++ WG + L
Sbjct: 70 ---YNITSSPTKLGGD---LAGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQ--LASV 121
Query: 200 RDEITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERS 259
D V + +FS K+ Q A G L+ G V+ WG G + G ++E +
Sbjct: 122 TDSTQVNVPRCL--HFSGVGKVRQAACGGTGCAVLNGEGHVFVWGYGILGK-GPNLVESA 178
Query: 260 RLRTLDPRPFGLD------NIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDG 313
+ P FGL + I G + AL+ G+L+ WG N G GI LED
Sbjct: 179 VPEMIPPTLFGLTEFNPEIQVSRIRCGLSRFAALTNKGELFVWGKNIRGCLGIG-RLEDQ 237
Query: 314 SLVSVPTEVILPEGVEIDSVSAGEHHTLILAKS 346
P V +P G +D V+ G H + LAKS
Sbjct: 238 YF---PWRVTMP-GEPVD-VACGVDHMVTLAKS 265
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/243 (23%), Positives = 99/243 (39%), Gaps = 28/243 (11%)
Query: 220 KIVQMAAGKDHILFLDETGIVYA--WGNGQQQQLGRRILERSRLRTLDPRPFGLD----N 273
++VQ+A G+DH LFL + G VY+ WG Q LG + T P G D N
Sbjct: 34 QVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNI------TSSPTKLGGDLAGVN 87
Query: 274 IKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSV 333
+ +++ + A+S DG L+ WG +++ Q T D + V+VP + ++
Sbjct: 88 VIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVT---DSTQVNVPRCLHFSGVGKVRQA 144
Query: 334 SAGEHHTLILAKSGDLYSCGRLDMFE-VGISKDKLPEYTYKDVHGKARSIPLPTKLEDVP 392
+ G +L G ++ G + + + + +PE + G T+
Sbjct: 145 ACGGTGCAVLNGEGHVFVWGYGILGKGPNLVESAVPEMIPPTLFGL-------TEFNPEI 197
Query: 393 SFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVFI 452
I G A+ G ++ WG +G+G +D P R+ T V +
Sbjct: 198 QVSRIRCGLSRFAALTNKGELFVWGKNIRGCLGIGRL-EDQYFPWRV----TMPGEPVDV 252
Query: 453 GCG 455
CG
Sbjct: 253 ACG 255
>CE19021 [S] KOG1426 FOG: RCC1 domain
Length = 522
Score = 60.5 bits (145), Expect = 6e-09
Identities = 58/240 (24%), Positives = 103/240 (42%), Gaps = 29/240 (12%)
Query: 220 KIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRR-----ILERSRLRTLDPRPFGLDN- 273
+I+++++G+ H L G V+A G+ Q GR + S L P F
Sbjct: 266 EILEISSGRAHSLIRTNLG-VFAIGDNNFGQCGRNPENMDYVVGSEESPLLPLSFPTSEP 324
Query: 274 IKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSV 333
I I + SF + + G ++S+GLN+ GQCG V +V EG +I V
Sbjct: 325 IISIHCSMDTSFVVDSSGAVFSFGLNEDGQCGNEAYGIQWEPAKVRGDV---EGSKIQKV 381
Query: 334 SAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPS 393
S L +++G+++ G+ + + + D++ T + V I
Sbjct: 382 SGSTDTLLACSENGEIFIWGQTEYGQAAGATDEIQLNTSRHVANSLGPI----------- 430
Query: 394 FKAIAAGSHHSLAIAKN--GIVYSWGFGETYAVGLGPSGDDIETPTRIKNTATQDHSIVF 451
I S S +A+N G V+ WG G +G+GP + ++TPT++ +++
Sbjct: 431 ---ICVDSTQSSVVARNSRGNVFVWGVG---VLGMGPEAESLKTPTQMDQPLFDGKMVIY 484
>7296072 [S] KOG1426 FOG: RCC1 domain
Length = 355
Score = 58.2 bits (139), Expect = 3e-08
Identities = 42/143 (29%), Positives = 66/143 (45%), Gaps = 4/143 (2%)
Query: 219 AKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILER--SRLRTLDPRPFGLDNIKY 276
A++ + G H+L LD +G ++A G + QLG E S + + FG ++
Sbjct: 14 AQVRLIRGGGGHVLILDTSGRIHACGWNNRGQLGLDSTEECHSEFKMIPTEYFGDVPVET 73
Query: 277 ISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAG 336
IS G + S A++ +L+ WG N F Q GI + V P V LP +S G
Sbjct: 74 ISCGWDISGAITLTKRLFVWGSNAFQQLGICQ--RGFTAVRRPMPVKLPREEPAQRISFG 131
Query: 337 EHHTLILAKSGDLYSCGRLDMFE 359
H +L + +Y GRL + +
Sbjct: 132 LRHCAVLTQDNKIYVFGRLRIMD 154
Score = 54.7 bits (130), Expect = 3e-07
Identities = 82/389 (21%), Positives = 139/389 (35%), Gaps = 100/389 (25%)
Query: 83 AKIVSFAAGGMHTLALDADNNIWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXL 142
A++ GG H L LD I + G N+ G LG D++
Sbjct: 14 AQVRLIRGGGGHVLILDTSGRIHACGWNNRGQLGLDSTEECH------------------ 55
Query: 143 NEIESTPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDE 202
+E + PT+ D +P++ + C ++S A+ ++ WG+ + LG +
Sbjct: 56 SEFKMIPTEYFGD-VPVETISCGW-----DISGAITLTKRLFVWGSNAFQQ--LGICQRG 107
Query: 203 ITVQKTPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLR 262
T + P + ++ +++ G H L + +Y +G RLR
Sbjct: 108 FTAVRRPMPV-KLPREEPAQRISFGLRHCAVLTQDNKIYVFG---------------RLR 151
Query: 263 TLDPRPFGLD----------------------NIKYISSGENHSFALSTD---------G 291
+DP P LD I ISSG+NH D
Sbjct: 152 IMDPPPIELDITATCLHRCNTVKIQVHNPNELRIVSISSGQNHMVLKCADLSETGGGSTK 211
Query: 292 KLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGDLYS 351
++ + G N+FGQ ED + ++ G H + K+ ++
Sbjct: 212 RILTLGDNKFGQSNAFQFEED-----------------VRQLAVGWTHNAAVLKNNEILV 254
Query: 352 CGRLDMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAKNG 411
GR ++G+ +A PL KL + I G+ H L G
Sbjct: 255 WGRNCYGQLGMGSFS---------EQQAIPTPLRLKLPEDQGPARIHMGAEHGLLRTTAG 305
Query: 412 IVYSWGFGETYAVGLGPSGDDIETPTRIK 440
VY+WG+ E G S +++ TPT ++
Sbjct: 306 EVYTWGWNEHGNCG-NNSTENVCTPTLLQ 333
Score = 50.8 bits (120), Expect = 4e-06
Identities = 75/315 (23%), Positives = 128/315 (39%), Gaps = 31/315 (9%)
Query: 148 TPTKIPRDSLPLDELRCVQIAATDNLSAALFENGDVYAWGTFRCNEGILGFYRDEITVQK 207
TP ++ + S ++R ++ L L +G ++A G N G LG E +
Sbjct: 2 TPQRVAKCSFAPAQVRLIRGGGGHVL--ILDTSGRIHACGWN--NRGQLGLDSTEECHSE 57
Query: 208 TPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPR 267
I + + ++ G D + T ++ WG+ QQLG I +R P
Sbjct: 58 FKMIPTEYFGDVPVETISCGWDISGAITLTKRLFVWGSNAFQQLG--ICQRGFTAVRRPM 115
Query: 268 PFGL---DNIKYISSGENHSFALSTDGKLYSWG-LNQFGQCGISTELEDGSLV---SVPT 320
P L + + IS G H L+ D K+Y +G L I ++ L +V
Sbjct: 116 PVKLPREEPAQRISFGLRHCAVLTQDNKIYVFGRLRIMDPPPIELDITATCLHRCNTVKI 175
Query: 321 EVILPEGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKAR 380
+V P + I S+S+G++H ++ C D+ E G K + G++
Sbjct: 176 QVHNPNELRIVSISSGQNHMVL--------KCA--DLSETGGGSTKRILTLGDNKFGQSN 225
Query: 381 SIPLPTKLEDVPSFKAIAAGSHHSLAIAKNGIVYSWGFGETYAVGLGPSGDD--IETPTR 438
+ EDV + +A G H+ A+ KN + WG +G+G + I TP R
Sbjct: 226 AFQFE---EDV---RQLAVGWTHNAAVLKNNEILVWGRNCYGQLGMGSFSEQQAIPTPLR 279
Query: 439 IKNTATQDHSIVFIG 453
+K Q + + +G
Sbjct: 280 LKLPEDQGPARIHMG 294
>CE12118 [S] KOG1426 FOG: RCC1 domain
Length = 178
Score = 57.0 bits (136), Expect = 6e-08
Identities = 31/91 (34%), Positives = 51/91 (55%), Gaps = 1/91 (1%)
Query: 215 FSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNI 274
F +IV+ AAG D ++F D TG +++ G G + +LG ++ R + G+ I
Sbjct: 77 FPWPVRIVEAAAGHDFLIFRDTTGNLFSMGTGTRGELGVGLIRRVDEPVHIEQLVGI-RI 135
Query: 275 KYISSGENHSFALSTDGKLYSWGLNQFGQCG 305
K ++ G H+ AL+ G Y+WG N++GQ G
Sbjct: 136 KKVACGGWHTVALTEGGDAYTWGWNRYGQLG 166
>Hs20547756 [S] KOG0783 Uncharacterized conserved protein contains ankyrin and
BTB/POZ domains
Length = 1353
Score = 55.8 bits (133), Expect = 1e-07
Identities = 57/204 (27%), Positives = 93/204 (44%), Gaps = 27/204 (13%)
Query: 162 LRCVQIAATDNLSAALFENGD---VYAWG---TFRCNEGILGFYRDEITVQKTPWIIPNF 215
L + + D + +F+N D VY WG F G + P ++ F
Sbjct: 120 LSALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHG-------SQNSKHHPELVDLF 172
Query: 216 SKKA-KIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPRPF-GLD- 272
S+ I Q+ K H +FL + G VY G+G +LG L PR GL+
Sbjct: 173 SRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHG----DEQTCLVPRLVEGLNG 228
Query: 273 -NIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILP--EGVE 329
N +++ ++H+ L+ DG +Y++GLN F Q GI + S +VP ++ +G
Sbjct: 229 HNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGI---IPPPSSCNVPRQIQAKYLKGRT 285
Query: 330 IDSVSAGEHHTLILAKSGDLYSCG 353
I V+AG HT++ + +Y+ G
Sbjct: 286 IIGVAAGRFHTVLWTREA-VYTMG 308
>Hs16716337_1 [S] KOG1426 FOG: RCC1 domain
Length = 953
Score = 55.8 bits (133), Expect = 1e-07
Identities = 49/178 (27%), Positives = 76/178 (42%), Gaps = 20/178 (11%)
Query: 240 VYAWGNGQQQQLGRRILERSRLRTLDPRPFGLDNIKYISSGENHSFALSTDGKLYSWGLN 299
V+ WG G++ QLG + RL+ L + + ++ +G HS AL+ ++YSWG N
Sbjct: 528 VWTWGKGKEGQLGHGDV-LPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSN 586
Query: 300 QFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAGEHHTLILAKSGD----LYSCGRL 355
FGQ G S +VP + + S++AG ++L L + D LY GR
Sbjct: 587 TFGQLGHS-----DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTEDFQPGLYYSGRQ 641
Query: 356 DMFEVGISKDKLPEYTYKDVHGKARSIPLPTKLEDVPSFKAIAAGSHHSLAIAKNGIV 413
D E D LPE + P+ + + AG LA+ I+
Sbjct: 642 DPTE----GDNLPE------NHSGSKTPVLLSCSKLGYISRVTAGKDSYLALVDKNIM 689
Score = 55.1 bits (131), Expect = 2e-07
Identities = 54/207 (26%), Positives = 95/207 (45%), Gaps = 24/207 (11%)
Query: 208 TPWIIPNFSKKAKIVQMAAGKDHILFLDETGIVYAWGNGQQQQLGRRILERSRLRTLDPR 267
TP +P + K ++Q A G H + L E G VY++G + I S + L+
Sbjct: 31 TPERLPGWGGKT-VLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPI--LENA 87
Query: 268 PFGLDNIKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTE--LEDGSLVSVPTEVILP 325
G + +++G HS A++ +G Y WG N GQC ++ + + + + VS+ P
Sbjct: 88 LVG-QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASP 146
Query: 326 -EGVEIDSVSAGEHHTLILAKSGDLYSCGRLDMFEVGISKDKLPEYTYKDVHGKARSIPL 384
V I ++ GE HTL L+ S ++++ G ++G+ P +
Sbjct: 147 LLAVRILQLACGEEHTLALSISREIWAWG--TGCQLGLITTAFP-------------VTK 191
Query: 385 PTKLEDVPS--FKAIAAGSHHSLAIAK 409
P K+E + +A G+ HSLA+ +
Sbjct: 192 PQKVEHLAGRVVLQVACGAFHSLALVQ 218
Score = 54.3 bits (129), Expect = 4e-07
Identities = 55/201 (27%), Positives = 83/201 (40%), Gaps = 44/201 (21%)
Query: 46 DIFVWGTGSMCELGLGPLAKNKEVKRPRLNPLLPR--DEAKIVSFAAGGMHTLALDADNN 103
+++ WG G +LG G + PRL PL + D +++ AGG H+LAL A +
Sbjct: 527 EVWTWGKGKEGQLGHGDVL-------PRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQ 579
Query: 104 IWSWGTNDSGALGRDTSGAVEKLKXXXXXXXXXXXXXXLNEIESTPTKIPRDSLPLDELR 163
++SWG+N G LG PT +PR + E
Sbjct: 580 VYSWGSNTFGQLGH----------------------------SDFPTTVPRLAKISSENG 611
Query: 164 CVQIAATDNLSAALFENGD----VYAWGTFRCNEGILGFYRDEITVQKTPWIIPNFSKKA 219
IAA + S L + D +Y G EG + + KTP ++ + SK
Sbjct: 612 VWSIAAGRDYSLFLVDTEDFQPGLYYSGRQDPTEG--DNLPENHSGSKTP-VLLSCSKLG 668
Query: 220 KIVQMAAGKDHILFLDETGIV 240
I ++ AGKD L L + I+
Sbjct: 669 YISRVTAGKDSYLALVDKNIM 689
>CE25842 [T] KOG1428 Inhibitor of type V adenylyl cyclases/Neuronal
presynaptic protein Highwire/PAM/RPM-1
Length = 1900
Score = 51.6 bits (122), Expect = 3e-06
Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 4/80 (5%)
Query: 274 IKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSV 333
+ +S G H+ L++D +++++G N GQ G+ L + P +VILP I V
Sbjct: 769 VSSVSCGNFHTVLLASDRRVFTFGSNCHGQLGVGDTLSKNT----PQQVILPSDTVIVQV 824
Query: 334 SAGEHHTLILAKSGDLYSCG 353
+AG +HT++ A G +++ G
Sbjct: 825 AAGSNHTILRANDGSVFTFG 844
>CE06730 [T] KOG1428 Inhibitor of type V adenylyl cyclases/Neuronal
presynaptic protein Highwire/PAM/RPM-1
Length = 3766
Score = 51.6 bits (122), Expect = 3e-06
Identities = 25/80 (31%), Positives = 45/80 (56%), Gaps = 4/80 (5%)
Query: 274 IKYISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSV 333
+ +S G H+ L++D +++++G N GQ G+ L + P +VILP I V
Sbjct: 769 VSSVSCGNFHTVLLASDRRVFTFGSNCHGQLGVGDTLSKNT----PQQVILPSDTVIVQV 824
Query: 334 SAGEHHTLILAKSGDLYSCG 353
+AG +HT++ A G +++ G
Sbjct: 825 AAGSNHTILRANDGSVFTFG 844
>7293028 [T] KOG1428 Inhibitor of type V adenylyl cyclases/Neuronal
presynaptic protein Highwire/PAM/RPM-1
Length = 2857
Score = 49.7 bits (117), Expect = 1e-05
Identities = 29/85 (34%), Positives = 50/85 (58%), Gaps = 6/85 (7%)
Query: 277 ISSGENHSFALSTDGKLYSWGLNQFGQCGISTELEDGSLVSVPTEVILPEGVEIDSVSAG 336
++ G +H+ L+ G++Y++G NQ+GQ G S +L+ VS P V +P I V+AG
Sbjct: 1061 VACGLHHTVVLTLAGEVYTFGSNQYGQLG-SGDLQP---VSGPVRVQVPGA--ISQVAAG 1114
Query: 337 EHHTLILAKSGDLYSCGRLDMFEVG 361
+HT++L G +Y+ G ++G
Sbjct: 1115 SNHTVLLTSKGMVYTFGNYQKGQLG 1139
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,980,769
Number of Sequences: 60738
Number of extensions: 1360387
Number of successful extensions: 3849
Number of sequences better than 1.0e-05: 47
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 2795
Number of HSP's gapped (non-prelim): 358
length of query: 480
length of database: 30,389,216
effective HSP length: 110
effective length of query: 370
effective length of database: 23,708,036
effective search space: 8771973320
effective search space used: 8771973320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)