ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI1878 good Z KOG2826 Cytoskeleton Actin-related protein Arp2/3 complex, subunit ARPC2
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI1878 672114 673091 326
(326 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNR035c [Z] KOG2826 Actin-related protein Arp2/3 complex subunit... 371 e-103
SPAC6F6.10c [Z] KOG2826 Actin-related protein Arp2/3 complex sub... 204 1e-52
Hs5031599 [Z] KOG2826 Actin-related protein Arp2/3 complex subun... 175 9e-44
7298678 [Z] KOG2826 Actin-related protein Arp2/3 complex subunit... 170 3e-42
CE26236_2 [Z] KOG2826 Actin-related protein Arp2/3 complex subun... 152 8e-37
>YNR035c [Z] KOG2826 Actin-related protein Arp2/3 complex subunit ARPC2
Length = 342
Score = 371 bits (952), Expect = e-103
Identities = 195/347 (56%), Positives = 249/347 (71%), Gaps = 26/347 (7%)
Query: 1 MLHLKPYNLLVQKTLTEALEAYNNGSPLTLDRIISDFDYTTLHITNDGTDKSNLLVSIRT 60
MLHL+P NLL+QKTL EA+EA GSPLT+DRI+SDFDYTT HI+N DKS LL+S++T
Sbjct: 1 MLHLQPQNLLIQKTLNEAIEALRKGSPLTMDRIVSDFDYTTYHISNTAEDKSILLLSVKT 60
Query: 61 KATQSCNESGND----LQGFLQAKFDEVPGLALSSAKKEAGYDFTITVDLSQITAQSIVQ 116
KA S +E D L FL + + G+ + S + E GYD+T+ + L+++ +SI+Q
Sbjct: 61 KAWVSVSECQLDGSLTLLKFLADHYSSLGGVTIPS-EVEPGYDYTLQITLAELVQESILQ 119
Query: 117 ASLFKILVMSYPFYLAFGQSNALSQLNEID--------QVEKSKEARAMVIKYRDDENIY 168
S+ K +++S+PF LA + LSQ +V + + IKYRD+ENI+
Sbjct: 120 LSVLKTIILSFPFELAISKFIELSQQQPAPVEAEITGGEVAANGDNTLFTIKYRDEENIF 179
Query: 169 IKPSFDRITVIFETIFQDETDKVFGKVFLQEFVDARKRNRSIQSAPQVLFSHEPPLEIQE 228
IKPS DR+T+IFETIFQDETDK+FGKVFLQEFVDARKRNR IQSAPQVL+SHEPPLE++
Sbjct: 180 IKPSNDRVTIIFETIFQDETDKIFGKVFLQEFVDARKRNRQIQSAPQVLYSHEPPLELKR 239
Query: 229 VAQQHAHVAGAKKSTRRFITFVLFPRHYSSDELMFTSVSQLALFRNYFHYHIKCAKAYMH 288
+ Q + +RRFITFVLFPRH+ + EL F S+ QL LFRNYFHYHIKC+KAYMH
Sbjct: 240 LYQP----PKVAEQSRRFITFVLFPRHFQTKELQFHSICQLTLFRNYFHYHIKCSKAYMH 295
Query: 289 SRMRYRVDTFIKVLNRAKLDEETESD---------SRRTITGRKMVY 326
SRMR+RVD+FIKVLNRAK+DE+ E+D +RRT TGRK+VY
Sbjct: 296 SRMRFRVDSFIKVLNRAKVDEDDENDELSAEGRQQARRTFTGRKIVY 342
>SPAC6F6.10c [Z] KOG2826 Actin-related protein Arp2/3 complex subunit ARPC2
Length = 317
Score = 204 bits (519), Expect = 1e-52
Identities = 135/340 (39%), Positives = 193/340 (56%), Gaps = 40/340 (11%)
Query: 1 MLHLKPYNLLVQKTLTEALEAYNNGSPLTLDRIISDFDYTTLHITNDGTDKSNLLVSIRT 60
ML L N+ + + LTE + N P ++D++++DFD T HI+ +K+ +L+S+
Sbjct: 1 MLSLDYNNIFIYELLTERFSSEN---PSSIDQVVTDFDGVTFHISTP-EEKTKILISLSM 56
Query: 61 KATQSCNESGN-DLQGFLQAKFDEVPGLALSSAKKEAGYDFTITVDLSQITA------QS 113
K G DL + + P E GY+F+I +DL Q+ A Q
Sbjct: 57 KCYPELVNYGTLDLLKQIYGAYVHEP---------EMGYNFSILIDLQQLPATDEEKEQL 107
Query: 114 IVQASLFKILVMSYPFYLAFGQSNALSQLNEIDQV------EKSKEARAMVIKYRDDENI 167
+ S+ K V++ PF+ AF + L+ L D +++ M I YRD+E I
Sbjct: 108 AMSISMLKRNVLAAPFHRAFTKQAELADLARKDPENAPMLDKQATSQELMAIHYRDEETI 167
Query: 168 YIKPSFDRITVIFETIFQDETDKVFGKVFLQEFVDARKRNRSIQSAPQVLFSH-EPPLEI 226
+ P DR+TV+F T F++ETD++FGKVFLQEFVDAR+R +IQ+APQVLFS+ +PPLEI
Sbjct: 168 VLWPEHDRVTVVFSTKFREETDRIFGKVFLQEFVDARRR-PAIQTAPQVLFSYRDPPLEI 226
Query: 227 QEVAQQHAHVAGAKKSTR-RFITFVLFPRHYSSDELMFTSVSQLALFRNYFHYHIKCAKA 285
++ + G +K F+TFVLF RH++ +S + +FRN H+HIK +KA
Sbjct: 227 RD-------IQGIQKGDDFGFVTFVLFERHFTPQN-REDCISHIQVFRNTLHFHIKASKA 278
Query: 286 YMHSRMRYRVDTFIKVLNRAKLDEETESDSRRTITGRKMV 325
YMH RMR RV F KVLNRAK D E E R+T TGR V
Sbjct: 279 YMHQRMRKRVADFQKVLNRAKPDVELE---RKTATGRSFV 315
>Hs5031599 [Z] KOG2826 Actin-related protein Arp2/3 complex subunit ARPC2
Length = 300
Score = 175 bits (443), Expect = 9e-44
Identities = 122/327 (37%), Positives = 176/327 (53%), Gaps = 37/327 (11%)
Query: 1 MLHLKPYNLLVQKTLTEALE-AYNNGSPLTLDRIISDFDYTTLHITNDGTDKSNLLVSIR 59
M+ L+ N ++++TL E A P ++ +DFD HI+N DK+ ++VSI
Sbjct: 1 MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSIS 60
Query: 60 TKATQSCNESGNDLQGFLQAKFDEVPGLALSSAKKEAGYDFTITVDLSQITAQ--SIV-Q 116
K + G D V G L E+GY+ ++ DL + A SIV Q
Sbjct: 61 LKFYKELQAHGAD------ELLKRVYGSFL--VNPESGYNVSLLYDLENLPASKDSIVHQ 112
Query: 117 ASLFKILVMSYPFYLAFGQSNALSQLNEIDQVEKSKEARAMVIKYRDDENIYIKPSFDRI 176
A + K + F F + + K E RA VI YRDDE +Y++ DR+
Sbjct: 113 AGMLKRNCFASVFEKYF----------QFQEEGKEGENRA-VIHYRDDETMYVESKKDRV 161
Query: 177 TVIFETIFQDETDKVFGKVFLQEFVDARKRNRSIQSAPQVLFSH-EPPLEIQEVAQQHAH 235
TV+F T+F+D+ D V GKVF+QEF + R R+ +APQVLFSH EPPLE+++
Sbjct: 162 TVVFSTVFKDDDDVVIGKVFMQEFKEGR---RASHTAPQVLFSHREPPLELKDTDAAVGD 218
Query: 236 VAGAKKSTRRFITFVLFPRHYSSDELMFTSVSQLALFRNYFHYHIKCAKAYMHSRMRYRV 295
G +ITFVLFPRH ++ +++ + FR+Y HYHIKC+KAY+H+RMR +
Sbjct: 219 NIG-------YITFVLFPRH-TNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKT 270
Query: 296 DTFIKVLNRAKLDEETESDSRRTITGR 322
F+KVLNRA+ D E +TITG+
Sbjct: 271 SDFLKVLNRARPD--AEKKEMKTITGK 295
>7298678 [Z] KOG2826 Actin-related protein Arp2/3 complex subunit ARPC2
Length = 293
Score = 170 bits (430), Expect = 3e-42
Identities = 117/328 (35%), Positives = 181/328 (54%), Gaps = 43/328 (13%)
Query: 1 MLHLKPYNLLVQKTLTEALEAYNNGS----PLTLDRIISDFDYTTLHITNDGTDKSNLLV 56
M+ L+ N ++++TL L Y N P ++D I+DFD HI+N DK+ + +
Sbjct: 1 MILLEINNRIIEETL---LVKYRNAQAGLKPESIDIRIADFDGVLYHISNVNGDKTKVRI 57
Query: 57 SIRTKATQSCNESGNDLQGFLQAKFDEVPGLALSSAKKEAGYDFTITVDLSQITAQSIVQ 116
SI K + E G D L+ ++ G L+ E GY+ ++ ++L +I
Sbjct: 58 SISLKFYKQLQEHGAD--ELLKREY----GSLLTDT--EEGYNVSVLINLEEIPEDCEQI 109
Query: 117 ASLFKILVMSYPFYLAFGQSNALSQLNE--IDQVEKSKEA-RAMVIKYRDDENIYIKPSF 173
A +L + N + + E D E+ +E + VI YR+DE +Y++
Sbjct: 110 AKRIGLL-----------KRNCFASVFEKYFDYQEQGEEGQKRAVINYRNDETLYVEAKP 158
Query: 174 DRITVIFETIFQDETDKVFGKVFLQEFVDARKRNRSIQSAPQVLFSH-EPPLEIQEVAQQ 232
DR+TV+F TIF+DE D + GKVF+QE + R R+ +APQVLFSH EPPLE+ +
Sbjct: 159 DRVTVVFSTIFRDEDDVIIGKVFMQELREGR---RASHTAPQVLFSHREPPLELANTDAR 215
Query: 233 HAHVAGAKKSTRRFITFVLFPRHYSSDELMFTSVSQLALFRNYFHYHIKCAKAYMHSRMR 292
G ++TFVLFPRH ++ E +++ + +FR+Y HYHIKC+KAY+HSRMR
Sbjct: 216 VGDNIG-------YVTFVLFPRH-TNKETRDNTINLIHMFRDYLHYHIKCSKAYIHSRMR 267
Query: 293 YRVDTFIKVLNRAKLDEETESDSRRTIT 320
+ F+KVLNRA+ E ++ ++TIT
Sbjct: 268 AKTSDFLKVLNRAR--PEPKNTEKKTIT 293
>CE26236_2 [Z] KOG2826 Actin-related protein Arp2/3 complex subunit ARPC2
Length = 301
Score = 152 bits (383), Expect = 8e-37
Identities = 108/327 (33%), Positives = 171/327 (52%), Gaps = 36/327 (11%)
Query: 1 MLHLKPYNLLVQKTLTEAL-EAYNNGSPLTLDRIISDFDYTTLHITNDGTDKSNLLVSIR 59
M+ L+ N ++ + L + A G P +++ +DFD ++N D++ +++SI
Sbjct: 1 MIILEQNNRIIVELLEQKFANAKEGGKPESVNVTFADFDGVLYKLSNPDGDRTKIILSIS 60
Query: 60 TKATQSCNESGNDLQGFLQAKFDEVPGLALSSAKKEAGYDFTITVDLSQITAQS---IVQ 116
K + G D V G + S E G++ T+ +L+ + A + +
Sbjct: 61 LKFYTELQQHGAD------DLLRRVYGGHMRSTP-EQGFNVTLEYNLADLPADTTDLVQA 113
Query: 117 ASLFKILVMSYPFYLAFGQSNALSQLNEIDQVEKSKEARAMVIKYRDDENIYIKPSFDRI 176
AS K + F F E + + RA VI YRDDE +YI+ DR+
Sbjct: 114 ASALKRNCFASVFEKYF----------EFQEAGQEGHKRA-VINYRDDETMYIEAKADRV 162
Query: 177 TVIFETIFQDETDKVFGKVFLQEFVDARKRNRSIQSAPQVLFS-HEPPLEIQEVAQQHAH 235
TVIF T+F+D D + GKVFLQEF + RK + Q+AP VL+S EPPLE++++ +
Sbjct: 163 TVIFSTVFKDADDVIIGKVFLQEFREGRKAS---QTAPAVLYSLGEPPLELKDLPEARV- 218
Query: 236 VAGAKKSTRRFITFVLFPRHYSSDELMFTSVSQLALFRNYFHYHIKCAKAYMHSRMRYRV 295
+ITFVLFPRH ++ + ++ + FR+Y HYHIKC+K Y+H+RMR +
Sbjct: 219 -----GDNVGYITFVLFPRH-TNKKTKDNTIDLIHSFRDYLHYHIKCSKVYLHTRMRAKT 272
Query: 296 DTFIKVLNRAKLDEETESDSRRTITGR 322
F+KVLNRA+ + + E ++T GR
Sbjct: 273 TDFLKVLNRARPEVKGE---KKTFHGR 296
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.134 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,489,754
Number of Sequences: 60738
Number of extensions: 681691
Number of successful extensions: 1815
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1790
Number of HSP's gapped (non-prelim): 5
length of query: 326
length of database: 30,389,216
effective HSP length: 107
effective length of query: 219
effective length of database: 23,890,250
effective search space: 5231964750
effective search space used: 5231964750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)