ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI1940 good O KOG0171 Posttranslational modification, protein turnover, chaperones Mitochondrial inner membrane protease, subunit IMP1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI1940 691582 692082 167
(167 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR150c [O] KOG0171 Mitochondrial inner membrane protease subuni... 229 2e-60
SPBC2D10.07c [O] KOG0171 Mitochondrial inner membrane protease s... 117 6e-27
At1g53530 [O] KOG0171 Mitochondrial inner membrane protease subu... 96 2e-20
Hs21450679 [O] KOG0171 Mitochondrial inner membrane protease sub... 95 4e-20
7302349 [OU] KOG1568 Mitochondrial inner membrane protease subun... 83 2e-16
7293105 [O] KOG0171 Mitochondrial inner membrane protease subuni... 82 4e-16
At1g29960_1 [O] KOG0171 Mitochondrial inner membrane protease su... 80 2e-15
At3g08980 [OU] KOG1568 Mitochondrial inner membrane protease sub... 77 8e-15
SPBC336.13c [OU] KOG1568 Mitochondrial inner membrane protease s... 74 1e-13
YMR035w [OU] KOG1568 Mitochondrial inner membrane protease subun... 72 3e-13
At1g23470_1 [O] KOG0171 Mitochondrial inner membrane protease su... 69 2e-12
Hs14211845 [OU] KOG1568 Mitochondrial inner membrane protease su... 67 1e-11
CE25490 [OU] KOG1568 Mitochondrial inner membrane protease subun... 55 4e-08
CE18529_1 [O] KOG0171 Mitochondrial inner membrane protease subu... 54 8e-08
>YMR150c [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 190
Score = 229 bits (583), Expect = 2e-60
Identities = 108/176 (61%), Positives = 133/176 (75%), Gaps = 13/176 (7%)
Query: 3 WLNIGSYVVRTVCLIHITHTHFYEFTETRGESMLPTLNRVNDYVHVLKWYKDGRDLKMGD 62
W SY +R++C +HI H + YEFTETRGESMLPTL+ NDYVHVLK +++GR +KMGD
Sbjct: 9 WSKTFSYAIRSLCFLHIIHMYAYEFTETRGESMLPTLSATNDYVHVLKNFQNGRGIKMGD 68
Query: 63 CIVAMKPTDPQSRVCKRITGMEGDLILVDPSQ--------EDDEEAYETFIRVPKGHVWV 114
CIVA+KPTDP R+CKR+TGM GDL+LVDPS DEE + T+I+VP+GHVWV
Sbjct: 69 CIVALKPTDPNHRICKRVTGMPGDLVLVDPSTIVNYVGDVLVDEERFGTYIKVPEGHVWV 128
Query: 115 TGDNLSHSLDSRTYNSIPKGLIKGKIVAANDFSKP-----LSTFWGFREITNSYFD 165
TGDNLSHSLDSRTYN++P GLI GKIVAAN+F KP + WGF+ I N++ D
Sbjct: 129 TGDNLSHSLDSRTYNALPMGLIMGKIVAANNFDKPFWDGSIRNIWGFKWINNTFLD 184
>SPBC2D10.07c [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 157
Score = 117 bits (294), Expect = 6e-27
Identities = 57/134 (42%), Positives = 83/134 (61%), Gaps = 7/134 (5%)
Query: 10 VVRTVCLIHITHTHFYEFTETRGESMLPTLNRVNDYVHVLKWY-KDGRDLKMGDCIVAMK 68
VV+ +H H + ++ T G SM+PTLN ++V + K + + R +GD +V+ K
Sbjct: 11 VVQIAAFVHQIHEYLFQVQMTSGPSMMPTLNSGGEFVLLDKLHGRFARSCSVGDVVVSAK 70
Query: 69 PTDPQSRVCKRITGMEGDLILVDPSQEDDEEAYETFIRVPKGHVWVTGDNLSHSLDSRTY 128
P+D + VCKRI GM GD I VDP+ + + I +P GHVW+ GDN++HSLDSR Y
Sbjct: 71 PSDSKQHVCKRIIGMPGDTIYVDPTSSNKK------ITIPLGHVWLAGDNIAHSLDSRNY 124
Query: 129 NSIPKGLIKGKIVA 142
+P GLIK K++A
Sbjct: 125 GPVPMGLIKAKVIA 138
>At1g53530 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 168
Score = 95.9 bits (237), Expect = 2e-20
Identities = 56/147 (38%), Positives = 78/147 (52%), Gaps = 7/147 (4%)
Query: 8 SYVVRTVCLIHITHTHFYEFTETRGESMLPTLNRVNDYVHVLKWYKDGRDLKMGDCIVAM 67
S V + +CL+H+T + T G SMLPTLN D + + +GD ++
Sbjct: 22 SIVAKFLCLLHVTDRYIISTTHVHGPSMLPTLNLTGDVILAEHLSHRFGKIGLGDVVLVR 81
Query: 68 KPTDPQSRVCKRITGMEGDLIL--VDPSQEDDEEAYETFIRVPKGHVWVTGDNLSHSLDS 125
P DP+ V KRI G+EGD + DP D + + VPKGHVW+ GDNL S DS
Sbjct: 82 SPRDPKRMVTKRILGLEGDRLTFSADPLVGDASVS----VLVPKGHVWIQGDNLYASTDS 137
Query: 126 RTYNSIPKGLIKGK-IVAANDFSKPLS 151
R + +P LI+GK ++ FSK L+
Sbjct: 138 RHFGPVPYSLIEGKALLRVTLFSKFLA 164
>Hs21450679 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 166
Score = 95.1 bits (235), Expect = 4e-20
Identities = 59/158 (37%), Positives = 81/158 (50%), Gaps = 14/158 (8%)
Query: 9 YVVRTVCLIHITHTHFYEFTETRGESMLPTLNRVNDYVHVLKWYKDGRDLKMGDCIVAMK 68
Y ++ C+ H + G SM PT+ +D V + ++ GD ++A
Sbjct: 15 YTIQYGCIAHCAFEYVGGVVMCSGPSMEPTIQN-SDIVFAENLSRHFYGIQRGDIVIAKS 73
Query: 69 PTDPQSRVCKRITGMEGDLILV-DPSQEDDEEAYETFIRVPKGHVWVTGDNLSHSLDSRT 127
P+DP+S +CKR+ G+EGD IL PS +Y VP GHVW+ GDNL +S DSR
Sbjct: 74 PSDPKSNICKRVIGLEGDKILTTSPSDFFKSHSY-----VPMGHVWLEGDNLQNSTDSRC 128
Query: 128 YNSIPKGLIKGKIVAANDFSK--PLSTFWGFREITNSY 163
Y IP GLI+G+I F K PLS F R N +
Sbjct: 129 YGPIPYGLIRGRI-----FFKIWPLSDFGFLRASPNGH 161
>7302349 [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 171
Score = 82.8 bits (203), Expect = 2e-16
Identities = 41/114 (35%), Positives = 63/114 (54%), Gaps = 10/114 (8%)
Query: 32 GESMLPTLNRV---NDYVHVLKWYKDGRDLKMGDCIVAMKPTDPQSRVCKRITGMEGDLI 88
G SM P LN V DYV +L+W ++ GD I + P DP ++ KR+ G++GD++
Sbjct: 32 GISMQPALNPVPDEKDYVFLLRWGTHNSQVERGDIISLISPKDPAQKIIKRVVGLQGDVV 91
Query: 89 LVDPSQEDDEEAYETFIRVPKGHVWVTGDNLSHSLDSRTYNSIPKGLIKGKIVA 142
+ + +RVP+GH WV GD+ HS+DS T+ + GL+ + VA
Sbjct: 92 STLGYKHE-------IVRVPEGHCWVEGDHTGHSMDSNTFGPVALGLMSARAVA 138
>7293105 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 166
Score = 81.6 bits (200), Expect = 4e-16
Identities = 46/143 (32%), Positives = 72/143 (50%), Gaps = 11/143 (7%)
Query: 9 YVVRTVCLIHITHTHFYEFTETRGESMLPTLNRVNDYVHVLKWYKDGRDLKMGDCIVAMK 68
Y V + H T + +F +G SM PTL+ N + + K R + GD ++A+
Sbjct: 13 YTVAYAAITHCTFEYIGDFVLCKGPSMEPTLHSDNVLL-TERLSKHWRTYQPGDIVIAIS 71
Query: 69 PTDPQSRVCKRITGMEGDLILVDP--------SQEDDEEAYETFIR--VPKGHVWVTGDN 118
P +CKRI + GD +L+ S D++ ++ VP+GHVW+ GDN
Sbjct: 72 PIKADQFICKRIVAVSGDQVLIQKPIPIEAEFSGNSDDKKKPVMVKDYVPRGHVWIEGDN 131
Query: 119 LSHSLDSRTYNSIPKGLIKGKIV 141
+S DSR Y IP GLI+ +++
Sbjct: 132 KGNSSDSRYYGPIPVGLIRSRVL 154
>At1g29960_1 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 153
Score = 79.7 bits (195), Expect = 2e-15
Identities = 44/137 (32%), Positives = 72/137 (52%), Gaps = 6/137 (4%)
Query: 7 GSYVVRTVCLIHITHTHFYEFTETRGESMLPTLNRVNDYVHVLKWYKDGRDLKMGDCIVA 66
G + + C +H+T + G SM PTL+ + + + K + GD +V
Sbjct: 20 GVLLAKLYCFLHVTTNYLGFMAYAYGPSMTPTLHPSGNVLLAERISKRYQKPSRGDIVVI 79
Query: 67 MKPTDPQSRVCKRITGMEGDLI--LVDPSQEDDEEAYETFIRVPKGHVWVTGDNLSHSLD 124
P +P KR+ G+EGD I ++D + D+ + I VPKGHV+V GD +S D
Sbjct: 80 RSPENPNKTPIKRVIGIEGDCISFVIDSRKSDESQT----IVVPKGHVFVQGDYTHNSRD 135
Query: 125 SRTYNSIPKGLIKGKIV 141
SR + ++P GLI+G+++
Sbjct: 136 SRNFGTVPYGLIQGRVL 152
>At3g08980 [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 154
Score = 77.4 bits (189), Expect = 8e-15
Identities = 47/115 (40%), Positives = 61/115 (52%), Gaps = 15/115 (13%)
Query: 31 RGESMLPTLNR-----VNDYVHVLKWYKDGRDLKMGDCIVAMKPTDPQSRVCKRITGMEG 85
RG+SM PT N ++DYV V K+ GD +V PT R KRI GM G
Sbjct: 35 RGDSMSPTFNPQRNSYLDDYVLVDKFCLKDYKFARGDVVVFSSPTHFGDRYIKRIVGMPG 94
Query: 86 DLILVDPSQEDDEEAYETFIRVPKGHVWVTGDNLSHSLDSRTYNSIPKGLIKGKI 140
+ I + IRVP+GH WV GDN + SLDSR++ IP GLI+G++
Sbjct: 95 EWI----------SSSRDVIRVPEGHCWVEGDNKTSSLDSRSFGPIPLGLIQGRV 139
>SPBC336.13c [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 180
Score = 73.6 bits (179), Expect = 1e-13
Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 10/132 (7%)
Query: 14 VCLIHITHTHFYEFTETRGESMLPTLNRVNDYVH---VLKWYKDGRDLKMGDCIVAMKPT 70
V ++ H G SM P N + + VL W K +D K GD ++ P
Sbjct: 26 VPVLMFVEQHVVSVGTIEGRSMKPAFNPETNMLQRDRVLLW-KWNKDYKRGDVVILRSPE 84
Query: 71 DPQSRVCKRITGMEGDLILVDPSQEDDEEAYETFIRVPKGHVWVTGDNLSHSLDSRTYNS 130
+P+ + KR+ G+E D++ P ++ + + VP+GHVWV GD HS+DS +
Sbjct: 85 NPEELLVKRVLGVEYDIMKTRPPKK------LSLVPVPEGHVWVEGDEQFHSIDSNKFGP 138
Query: 131 IPKGLIKGKIVA 142
+ GLI K++A
Sbjct: 139 VSTGLITAKVIA 150
>YMR035w [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 177
Score = 72.4 bits (176), Expect = 3e-13
Identities = 43/120 (35%), Positives = 64/120 (52%), Gaps = 14/120 (11%)
Query: 29 ETRGESMLPTLNRVNDYVH---VLKW---YKDGRDLKMGDCIVAMKPTDPQSRVCKRITG 82
+ +G SM PTLN + + VL W K+ +L D I+ PT+P+ CKR+ G
Sbjct: 36 QVKGTSMQPTLNPQTETLATDWVLLWKFGVKNPSNLSRDDIILFKAPTNPRKVYCKRVKG 95
Query: 83 MEGDLILVDPSQEDDEEAY-ETFIRVPKGHVWVTGDNLSHSLDSRTYNSIPKGLIKGKIV 141
+ D I D + Y + + +P+GH+WV GDN HS+DS T+ I GL+ GK +
Sbjct: 96 LPFDTI-------DTKFPYPKPQVNLPRGHIWVEGDNYFHSIDSNTFGPISSGLVIGKAI 148
>At1g23470_1 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 175
Score = 69.3 bits (168), Expect = 2e-12
Identities = 50/141 (35%), Positives = 73/141 (51%), Gaps = 10/141 (7%)
Query: 6 IGSYVVRTVCLIHITHTHFYEFTETRGESML-PTLNRVNDYVHVLKWYKDGRDLK--MGD 62
IG+ V V L H + T +E ES+L + N +H L R K GD
Sbjct: 38 IGNDVAVIVFLEH-SFTRSHEKRHVCRESLLLSSCNNKLSRIHGLSERISKRYQKPSRGD 96
Query: 63 CIVAMKPTDPQSRVCKRITGMEGDLI--LVDPSQEDDEEAYETFIRVPKGHVWVTGDNLS 120
+V P +P KR+ G+EGD I ++DP + D+ + I VPKGHV+V GD
Sbjct: 97 IVVIRSPENPNKTPIKRVVGVEGDCISFVIDPVKSDESQT----IVVPKGHVFVQGDYTH 152
Query: 121 HSLDSRTYNSIPKGLIKGKIV 141
+S DSR + +P GLI+G+++
Sbjct: 153 NSRDSRNFGPVPYGLIQGRVL 173
>Hs14211845 [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 175
Score = 67.0 bits (162), Expect = 1e-11
Identities = 32/109 (29%), Positives = 59/109 (53%), Gaps = 11/109 (10%)
Query: 32 GESMLPTLN----RVNDYVHVLKWYKDGRDLKMGDCIVAMKPTDPQSRVCKRITGMEGDL 87
G SM P+LN + +D V + W ++ GD + + P +P+ ++ KR+ +EGD+
Sbjct: 41 GASMQPSLNPGGSQSSDVVLLNHWKVRNFEVHRGDIVSLVSPKNPEQKIIKRVIALEGDI 100
Query: 88 ILVDPSQEDDEEAYETFIRVPKGHVWVTGDNLSHSLDSRTYNSIPKGLI 136
+ + +++VP+GH+WV GD+ HS DS ++ + GL+
Sbjct: 101 VRTIGHKN-------RYVKVPRGHIWVEGDHHGHSFDSNSFGPVSLGLL 142
>CE25490 [OU] KOG1568 Mitochondrial inner membrane protease subunit IMP2
Length = 152
Score = 55.1 bits (131), Expect = 4e-08
Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 25/119 (21%)
Query: 32 GESMLPTLNRVNDYVHVLKWYKDGRDL-----------KMGDCIVAMKPTDPQSRVCKRI 80
G SM PTL + +WYK RD+ G + + P DP + KR+
Sbjct: 32 GNSMQPTLQGGD-----ARWYK--RDIVWLSTWNLYKCSPGTILTFVSPRDPDAVHIKRV 84
Query: 81 TGMEGDLILVDPSQEDDEEAYETFIRVPKGHVWVTGDNLSHSLDSRTYNSIPKGLIKGK 139
T +E ++ E+ E +PKGH W+ GDN H DS Y + L+KG+
Sbjct: 85 TAVENAIVR-------PEKRPELITDIPKGHYWMEGDNPEHRHDSNVYGPVSTSLVKGR 136
>CE18529_1 [O] KOG0171 Mitochondrial inner membrane protease subunit IMP1
Length = 131
Score = 54.3 bits (129), Expect = 8e-08
Identities = 35/108 (32%), Positives = 56/108 (51%), Gaps = 14/108 (12%)
Query: 32 GESMLPTLNRVNDYVHVLKWYKDGRDLKMGDCIVAMKPTDPQSRVCKRITGMEGDLILVD 91
G SM PT++ D V ++ +++++GD + + P P+ +CKRI EGD +
Sbjct: 6 GPSMHPTIHD-GDLVLAERFSIRNKNVQVGDIVGCVNPQKPKELLCKRIAAKEGDPVTSH 64
Query: 92 --PSQEDDEEAYETFIRVPKGHVWVTGDNLSHSLDSRTYNSIPKGLIK 137
PS RVP GHV++ GDN S DSR + +P+ L++
Sbjct: 65 LLPSG-----------RVPIGHVFLRGDNGPVSTDSRHFGPVPEALVQ 101
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.138 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,219,025
Number of Sequences: 60738
Number of extensions: 470607
Number of successful extensions: 1110
Number of sequences better than 1.0e-05: 14
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1084
Number of HSP's gapped (non-prelim): 14
length of query: 167
length of database: 30,389,216
effective HSP length: 98
effective length of query: 69
effective length of database: 24,436,892
effective search space: 1686145548
effective search space used: 1686145548
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)