ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2025 good E KOG1287 Amino acid transport and metabolism Amino acid transporters
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2025 725763 724207 -519
(519 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR055w [E] KOG1287 Amino acid transporters 245 1e-64
YHL036w [E] KOG1287 Amino acid transporters 168 2e-41
Hs4507053 [E] KOG1287 Amino acid transporters 118 2e-26
7294339 [E] KOG1287 Amino acid transporters 116 9e-26
Hs21361563 [E] KOG1287 Amino acid transporters 113 6e-25
HsM4507055 [E] KOG1287 Amino acid transporters 112 1e-24
7301546 [E] KOG1287 Amino acid transporters 104 3e-22
Hs9790235 [E] KOG1287 Amino acid transporters 103 5e-22
Hs7657683 [E] KOG1287 Amino acid transporters 103 8e-22
Hs6912670 [E] KOG1287 Amino acid transporters 102 2e-21
Hs7657591 [E] KOG1287 Amino acid transporters 99 2e-20
Hs19923170 [E] KOG1287 Amino acid transporters 96 1e-19
7302046 [E] KOG1287 Amino acid transporters 96 1e-19
CE28440 [E] KOG1287 Amino acid transporters 96 2e-19
CE07028 [E] KOG1287 Amino acid transporters 89 2e-17
CE27888 [E] KOG1287 Amino acid transporters 87 5e-17
CE09028 [E] KOG1287 Amino acid transporters 87 5e-17
CE22438 [E] KOG1287 Amino acid transporters 86 2e-16
CE03266 [E] KOG1287 Amino acid transporters 81 4e-15
7292991 [E] KOG1287 Amino acid transporters 76 1e-13
7297908 [E] KOG1287 Amino acid transporters 75 2e-13
CE07491 [E] KOG1287 Amino acid transporters 70 6e-12
Hs20270383 [E] KOG1287 Amino acid transporters 69 2e-11
CE17868 [E] KOG1287 Amino acid transporters 61 4e-09
CE17028 [E] KOG1287 Amino acid transporters 51 4e-06
CE06416 [E] KOG1287 Amino acid transporters 51 4e-06
Hs13654280 [E] KOG1287 Amino acid transporters 50 6e-06
>YGR055w [E] KOG1287 Amino acid transporters
Length = 574
Score = 245 bits (626), Expect = 1e-64
Identities = 154/469 (32%), Positives = 234/469 (49%), Gaps = 23/469 (4%)
Query: 34 EHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLE 93
E +L I LI NR++GTG+F+ + I+TL S+G++LI+W +G I +GL VY+E
Sbjct: 58 EKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCG-SVGLALIMWAVGAIIAISGLYVYME 116
Query: 94 FGLKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSS 153
FG IPK+GGEKNYL KPK I C+YA I LG+++GNS I + F ++
Sbjct: 117 FGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNS------INTAIMFLTA 170
Query: 154 LSETVIDKASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIA 213
V R IG V+ L + +A+
Sbjct: 171 ADTEVTKWNQRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGG 230
Query: 214 PNLIEPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTLMI 273
NF N+F G++ Y I AL VI+SF G+ N NY L E+++P RTL I
Sbjct: 231 GLKDGYQSHNFRNAFE-GTETATAYGIVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKI 289
Query: 274 AAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIVSRV 333
A P S+ +YI + +Y+ V+PK ++ + ++++ FF+ +F +K A +V
Sbjct: 290 AGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFGGQAKRAAAALVG-- 347
Query: 334 LPFCIILSNYGNVMAVSFSNARVNQELAKEGIFPLTHLFSKLN------YALFLHCFITI 387
LS GNV++V FS R+ Q+L +EG+ P ++ F+ LF H +
Sbjct: 348 ------LSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQHFIVCT 401
Query: 388 VVLLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTV 447
V +L PP G+ Y L+ +L +YP N I GL++I+W G + P + VT
Sbjct: 402 VTILAPPPGDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVTG 461
Query: 448 IFIISNLFLAVIPFVPP-NGSVENDGYSYWVFPVTGISIMGVGALYWLL 495
F +SNL+L + P+VPP NG YW+ V I G +Y+++
Sbjct: 462 FFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVV 510
>YHL036w [E] KOG1287 Amino acid transporters
Length = 546
Score = 168 bits (425), Expect = 2e-41
Identities = 123/439 (28%), Positives = 205/439 (46%), Gaps = 29/439 (6%)
Query: 32 PHEHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVY 91
P L F T+ L V+RI+G+GIF+ P++I + + I +WV FAGL ++
Sbjct: 60 PQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLYLF 119
Query: 92 LEFGLKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFN 151
LEFG IPKSGG KN+L R+ +P+ LI +++ VL G++ S FGKY++ G
Sbjct: 120 LEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFGVT 179
Query: 152 SSLSETVIDKASRYIGSLVIISCTLWH-IFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIA 210
D S+Y+ II L H + G
Sbjct: 180 D-------DSWSKYVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLYTL 232
Query: 211 IIAPNLIEPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRT 270
+ + WD S L SI+ A + + F GW+ + V E+++P +T
Sbjct: 233 FFYKSTGQVAWDLPVTQVEKDSL-LSVSSIATAFISSFFCFSGWDTVHTVTSEIKNPVKT 291
Query: 271 LMIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIV 330
L ++ P+S+ + Y + +Y V+ EI G L+ V F ++F ++
Sbjct: 292 LKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLF-------GPRVG 344
Query: 331 SRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFPLTHLFSKLNY-------ALFLHC 383
+ + F I +S N++ V +S +RVNQE+ KEG P + SK N+ ++ L
Sbjct: 345 GKFIAFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSK-NWPFDAPLPSISLCG 403
Query: 384 FITIV-VLLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSW 442
FITI +L+LP G + ++ + Y + +F L++ IGL + + N++ +S
Sbjct: 404 FITIAWILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHK---NEVPEIRAST 460
Query: 443 YLVTVIFIISNLFLAVIPF 461
+ V I +S L++ + PF
Sbjct: 461 FGVLAIITLS-LYMLMAPF 478
>Hs4507053 [E] KOG1287 Amino acid transporters
Length = 515
Score = 118 bits (295), Expect = 2e-26
Identities = 98/432 (22%), Positives = 199/432 (45%), Gaps = 39/432 (9%)
Query: 36 KLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFG 95
+++ + +SL+V +IG+GIF +P + + S G+SLI+W +GG+F+ G Y E G
Sbjct: 44 EISLLNGVSLVVGNMIGSGIFVSPKGVL-VHTASYGMSLIVWAIGGLFSVVGALCYAELG 102
Query: 96 LKIPKSGGEKNYLSRTLPKPKHLIECIYAF-TIVLLGFSSGNSYAFGKYIIYVLGFNSSL 154
I KSG Y+ +E F + L S G+ II + N +
Sbjct: 103 TTITKSGASYAYI----------LEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANYII 152
Query: 155 SETVIDKASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIAP 214
+ Y+ ++ + + + F A I +
Sbjct: 153 QPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLV 212
Query: 215 NLIEPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTLMIA 274
L + H ++F ++F S D ++S+AL ++S+ GW+ N+V EE+++P R L +A
Sbjct: 213 KLCQGHSEHFQDAFEGSSW--DMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLA 270
Query: 275 APVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIVSRVL 334
+S+ + T +YI +YY V+ +++ + ++ F ++ F +S + +
Sbjct: 271 IGISMPIVTLIYILTNVAYYTVLNISDVLSSD-AVAVTFADQTFGMFSWT---------I 320
Query: 335 PFCIILSNYGNVMAVSFSNARVNQELAKEGIFP----LTHL--FSKLNYALFLHCFITIV 388
P + LS +G + A F+++R+ ++EG P + H+ F+ + AL +C + ++
Sbjct: 321 PIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIP-ALLFNCTMALI 379
Query: 389 VLLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTVI 448
L++ +++QL I+ +++ +F + +G +Y+ W P ++
Sbjct: 380 YLIVE---DVFQL-INYFSFSYWFFVGLSVVGQLYLRWKEP----KRPRPLKLSVFFPIV 431
Query: 449 FIISNLFLAVIP 460
F I ++FL ++P
Sbjct: 432 FCICSVFLVIVP 443
>7294339 [E] KOG1287 Amino acid transporters
Length = 499
Score = 116 bits (290), Expect = 9e-26
Identities = 111/435 (25%), Positives = 197/435 (44%), Gaps = 38/435 (8%)
Query: 43 ISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFGLKIPKSG 102
+++IV I+G+GIF +P + S SIG SLI+WVL G+ + G Y E G IPKSG
Sbjct: 49 VAIIVGVIVGSGIFVSPKGVLKFSG-SIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSG 107
Query: 103 GEKNYLSRTL-PKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLG-FNSSLSETVID 160
G+ Y+ P P L Y + +L+ +GN+ + IY+L F S +
Sbjct: 108 GDYAYIGTAFGPLPAFL----YLWVALLILVPTGNAITALTFAIYLLKPFWPSCDAPI-- 161
Query: 161 KASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIAPNLIEPH 220
+A + + + +I TL + + R + N H
Sbjct: 162 EAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDGNT--EH 219
Query: 221 WDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTLMIAAPVSVG 280
WDN FS G Q + I++A ++S+ GW N+V EEL+DP R L A +S+
Sbjct: 220 WDN---PFSGGLQDPGY--IALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMP 274
Query: 281 LTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIVSRVLPFCIIL 340
+ T +Y+ +Y+ V+ EI + ++ F +++ + +S ++PF +
Sbjct: 275 VVTVIYMITNIAYFSVLSPDEILSSD-AVAVTFGDKM---------LGYMSWIMPFAVAC 324
Query: 341 SNYGNVMAVSFSNARVNQELAKEGIFPLTHLFSKLNYALFLH--CFITIVVLLLPPNGNI 398
S +G++ F+++R+ A+ G P +N + F+ ++ LLL ++
Sbjct: 325 STFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDV 384
Query: 399 YQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTVIFIISNLFLAV 458
Y ++I+ +Y F LI GL+++ + P + +I++I LFL +
Sbjct: 385 Y-VLINYVSYVEALFTLISVSGLLWMRYKQP----KTERPIKVNLALPIIYLIVCLFLVI 439
Query: 459 I-----PFVPPNGSV 468
P+V G++
Sbjct: 440 FSCTQTPYVVGIGTI 454
>Hs21361563 [E] KOG1287 Amino acid transporters
Length = 511
Score = 113 bits (283), Expect = 6e-25
Identities = 111/474 (23%), Positives = 213/474 (44%), Gaps = 58/474 (12%)
Query: 36 KLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFG 95
+++ + + LIV +IG+GIF +P + S S G+SL++W +GG+F+ G Y+E G
Sbjct: 36 EISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA-SFGLSLVIWAVGGLFSVFGALCYVELG 94
Query: 96 LKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSSLS 155
I KSG Y+ I + I+ + + F Y++ L F S +
Sbjct: 95 TTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPL-FPSCFA 153
Query: 156 ETVIDK--ASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIA 213
+ A+ I L I+C ++ + T + IA+I
Sbjct: 154 PYAASRLLAAACICLLTFINCA--YVKWGTLVQDIFTYAKVLAL-----------IAVIV 200
Query: 214 PNLI---EPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRT 270
++ + +F NSF S + I++AL ++S+ GW+ NYV EE+++P R
Sbjct: 201 AGIVRLGQGASTHFENSFEGSSFAVG--DIALALYSALFSYSGWDTLNYVTEEIKNPERN 258
Query: 271 LMIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIV 330
L ++ +S+ + T +YI +YY V+ +I + ++ F ++IF I
Sbjct: 259 LPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASD-AVAVTFADQIF---------GIF 308
Query: 331 SRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFP----LTHL--FSKLNYALFLHCF 384
+ ++P + LS +G + A + +R+ ++EG P + H+ F+ + LF +
Sbjct: 309 NWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLF-NGI 367
Query: 385 ITIVVLLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYL 444
+ ++ L + +I+QL I+ Y++ +F + +G +Y+ W D P
Sbjct: 368 MALIYLCVE---DIFQL-INYYSFSYWFFVGLSIVGQLYLRWKEP----DRPRPLKLSVF 419
Query: 445 VTVIFIISNLFLAVIPFVPPNGSVENDGYSYWVFPVTGISIMGVGALYWLLVVR 498
++F + +FL +P YS + + GI+I G ++ L++R
Sbjct: 420 FPIVFCLCTIFLVAVPL-----------YSDTINSLIGIAIALSGLPFYFLIIR 462
>HsM4507055 [E] KOG1287 Amino acid transporters
Length = 511
Score = 112 bits (281), Expect = 1e-24
Identities = 111/474 (23%), Positives = 212/474 (44%), Gaps = 58/474 (12%)
Query: 36 KLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFG 95
+++ + + LIV +IG+GIF +P + S S G+SL++W +GG+F+ G Y E G
Sbjct: 36 EISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA-SFGLSLVIWAVGGLFSVFGALCYAELG 94
Query: 96 LKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSSLS 155
I KSG Y+ I + I+ + + F Y++ L F S +
Sbjct: 95 TTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPL-FPSCFA 153
Query: 156 ETVIDK--ASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIA 213
+ A+ I L I+C ++ + T + IA+I
Sbjct: 154 PYAASRLLAAACICLLTFINCA--YVKWGTLVQDIFTYAKVLAL-----------IAVIV 200
Query: 214 PNLI---EPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRT 270
++ + +F NSF S + I++AL ++S+ GW+ NYV EE+++P R
Sbjct: 201 AGIVRLGQGASTHFENSFEGSSFAVG--DIALALYSALFSYSGWDTLNYVTEEIKNPERN 258
Query: 271 LMIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIV 330
L ++ +S+ + T +YI +YY V+ +I + ++ F ++IF I
Sbjct: 259 LPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASD-AVAVTFADQIF---------GIF 308
Query: 331 SRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFP----LTHL--FSKLNYALFLHCF 384
+ ++P + LS +G + A + +R+ ++EG P + H+ F+ + LF +
Sbjct: 309 NWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLF-NGI 367
Query: 385 ITIVVLLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYL 444
+ ++ L + +I+QL I+ Y++ +F + +G +Y+ W D P
Sbjct: 368 MALIYLCVE---DIFQL-INYYSFSYWFFVGLSIVGQLYLRWKEP----DRPRPLKLSVF 419
Query: 445 VTVIFIISNLFLAVIPFVPPNGSVENDGYSYWVFPVTGISIMGVGALYWLLVVR 498
++F + +FL +P YS + + GI+I G ++ L++R
Sbjct: 420 FPIVFCLCTIFLVAVPL-----------YSDTINSLIGIAIALSGLPFYFLIIR 462
>7301546 [E] KOG1287 Amino acid transporters
Length = 517
Score = 104 bits (260), Expect = 3e-22
Identities = 111/480 (23%), Positives = 216/480 (44%), Gaps = 48/480 (10%)
Query: 36 KLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFG 95
+L +++I+ I G+GIF +P + +S+G SL++WVL G+ + G Y E G
Sbjct: 58 QLGLLEGVAIILGIIFGSGIFVSPKGVIR-EVESVGASLVIWVLCGLLSMIGALCYAELG 116
Query: 96 LKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSSLS 155
IPKSGG+ Y+ L +Y + +++ + N+ + YVL +
Sbjct: 117 TAIPKSGGDYAYIFEAYGS---LPAFLYLWDAMMIFVPTTNAIMGLTFASYVLEPFFGGA 173
Query: 156 ETVIDKASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIAPN 215
+ A + + ++ I T + ++ + + ++ N
Sbjct: 174 CEIPKIALQLLAAITICFLTYLNSYYMKVTTKMQNVIMFTKIAALVLIILVGLVWMMMGN 233
Query: 216 LIEPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTLMIAA 275
+ +NF F N D +SVA I+S+ GW N++ EEL DP R L A
Sbjct: 234 V-----ENFTRPFDNTET--DPGKMSVAFYSGIFSYAGWNYLNFMTEELRDPYRNLPRAI 286
Query: 276 PVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIVSRVLP 335
+S+ L T +Y+ +Y V+ +E+ + I+ F ++I + + S ++P
Sbjct: 287 YISLPLVTGIYVLANVAYLAVLSPSEMIASN-AIAVTFGDKI---------LGVFSLIIP 336
Query: 336 FCIILSNYGNVMAVSFSNARVNQELAKEGIFP--LTHL----FSKLNYALFLHCFITIVV 389
+ +S +G + +++R+ A+ G P L+H+ ++ L +FL CF++IV+
Sbjct: 337 LMVAISAFGGLSVHIMTSSRICFVGARNGHMPAILSHISVKSYTPLPSLVFL-CFLSIVM 395
Query: 390 LLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTVIF 449
L++ ++Y ++I + +F ++ ++Y +T I + W + +F
Sbjct: 396 LVV---SDVY-VLITYASIVESFFIMLSVSAVLYFRYTRPCMERPIKV--AMW--IPALF 447
Query: 450 IISNLFLAVIP-FVPPNGSVENDGYSYWVFPVTGISIMGVGALYWLLVVRKSYSRYSSAT 508
+I FL V+P +V P Y V I+I+G+ Y++ VV K+ ++ +T
Sbjct: 448 VIVCAFLVVVPIYVAP----------YEVGMGVLITIIGI-PFYYVGVVWKNKPKWVQST 496
>Hs9790235 [E] KOG1287 Amino acid transporters
Length = 523
Score = 103 bits (258), Expect = 5e-22
Identities = 107/429 (24%), Positives = 186/429 (42%), Gaps = 42/429 (9%)
Query: 44 SLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFGLKIPKSGG 103
++I+ IIG+GIF +P + S S+G++L +WVLGG T G Y E G+ IPKSGG
Sbjct: 47 TIIIGNIIGSGIFISPKGVLEHSG-SVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGG 105
Query: 104 EKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSSLSETVIDKAS 163
+ Y++ + A I+ + S F Y++ + F + + T AS
Sbjct: 106 DYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPV-FPNCIPPTT---AS 161
Query: 164 RYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIAPNLIEPHWDN 223
R + ++ T + A R I + + + H++
Sbjct: 162 RVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLI-----IGVGLLQIFQGHFEE 216
Query: 224 FH--NSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTLMIAAPVSVGL 281
N+F+ P + +++A LQ ++F GW NYV EE+ D R+ L A +S+ L
Sbjct: 217 LRPSNAFAFWMTPSVGH-LALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPL 275
Query: 282 TTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIVSRVLPFCIILS 341
TF+Y +Y+ + E+ + ++ F E++ + S V+P + LS
Sbjct: 276 VTFVYTFTNIAYFTAMSPQELLSSN-AVAVTFGEKLLGYF---------SWVMPVSVALS 325
Query: 342 NYGNVMAVSFSNARVNQELAKEGIFPLTHLFSKLNY-----ALFLHCFITIVVLLLPPNG 396
+G + F+ +R+ A+EG P + + AL + C T V++L+ G
Sbjct: 326 TFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLV---G 382
Query: 397 NIYQLIIDLYAYPSGWFNLIIGI---GLIYIHWTNDGGWNDIYTPWSSWYLVTVIFIISN 453
+ Y LI Y S L G+ GL+ + W ++ P L+ V +++
Sbjct: 383 DTYTLI----NYVSFINYLCYGVTILGLLLLRWRRPA----LHRPIKVNLLIPVAYLVFW 434
Query: 454 LFLAVIPFV 462
FL V F+
Sbjct: 435 AFLLVFSFI 443
>Hs7657683 [E] KOG1287 Amino acid transporters
Length = 501
Score = 103 bits (256), Expect = 8e-22
Identities = 105/472 (22%), Positives = 206/472 (43%), Gaps = 52/472 (11%)
Query: 34 EHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLE 93
+ K+ +S+I+ IIG GIF +P + + S+G+SL +W + G+ + G Y E
Sbjct: 41 KRKVTLLRGVSIIIGTIIGAGIFISPKGVLQ-NTGSVGMSLTIWTVCGVLSLFGALSYAE 99
Query: 94 FGLKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSS 153
G I KSGG Y+ + I+ ++ S AFG+YI+
Sbjct: 100 LGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPFFIQCE 159
Query: 154 LSETVIDKASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIA 213
+ E I K +G V++ + + + + II
Sbjct: 160 IPELAI-KLITAVGITVVMVLNSMSVSWSARIQ-----------IFLTFCKLTAILIIIV 207
Query: 214 PN---LIEPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRT 270
P LI+ NF ++FS + + +A +Y++ GW N+V EE+E+P +T
Sbjct: 208 PGVMQLIKGQTQNFKDAFSGRDSSIT--RLPLAFYYGMYAYAGWFYLNFVTEEVENPEKT 265
Query: 271 LMIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIV 330
+ +A +S+ + T Y+ +Y+ I E+ + ++ F ER+ +S +
Sbjct: 266 IPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSN-AVAVTFSERLLGNFSLA------ 318
Query: 331 SRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFP----LTHL--FSKLNYALFLHCF 384
+P + LS +G++ F+ +R+ ++EG P + H+ + L + LH
Sbjct: 319 ---VPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHP- 374
Query: 385 ITIVVLLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYL 444
+T+++L +G++ L ++ ++ F + GLIY+ + D++ P+
Sbjct: 375 LTMIMLF---SGDLDSL-LNFLSFARWLFIGLAVAGLIYLRYK----CPDMHRPFKVPLF 426
Query: 445 VTVIFIISNLFLAVIPFVPPNGSVENDGYSYWVFPVTGISIMGVGALYWLLV 496
+ +F + LF+ + S+ +D +S + V I++ GV A Y ++
Sbjct: 427 IPALFSFTCLFMVAL-------SLYSDPFSTGIGFV--ITLTGVPAYYLFII 469
>Hs6912670 [E] KOG1287 Amino acid transporters
Length = 535
Score = 102 bits (253), Expect = 2e-21
Identities = 109/458 (23%), Positives = 192/458 (41%), Gaps = 43/458 (9%)
Query: 45 LIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFGLKIPKSGGE 104
+IV IIG+GIF +P + + S+G++LI+W++ G T G Y E G+ IPKSGG+
Sbjct: 48 IIVGNIIGSGIFVSPKGVLE-NAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGD 106
Query: 105 KNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSSLSETVIDKASR 164
+Y+ + A ++ + + F Y++ L E+ + R
Sbjct: 107 YSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGL----R 162
Query: 165 YIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIAPNLIEPHWDNF 224
+ ++ ++ T + A R + I E W
Sbjct: 163 LLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKG---EYFWLEP 219
Query: 225 HNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTLMIAAPVSVGLTTF 284
N+F + +P D +++A LQ +++ GW NYV EEL DP + L A +S+ L TF
Sbjct: 220 KNAFEDFQEP-DIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTF 278
Query: 285 LYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIVSRVLPFCIILSNYG 344
+Y+ +Y + E+ + ++ F E++ + +++ ++P + LS +G
Sbjct: 279 VYVFANVAYVTAMSPQELLASN-AVAVTFGEKL---------LGVMAWIMPISVALSTFG 328
Query: 345 NVMAVSFSNARVNQELAKEGIFP--LTHLFSKLNYALFLHCFITIVVLLLPPNGNIYQLI 402
V F+++R+ A+EG P L + K + F I LL+ ++Y L
Sbjct: 329 GVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTL- 387
Query: 403 IDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTVIFIISNLFLAVIPFV 462
I+ + + F G I + W DI P L +I+++ FL V
Sbjct: 388 INYVGFINYLFYGGTVAGQIVLRWKKP----DIPRPIKINLLFPIIYLLFWAFLLV---- 439
Query: 463 PPNGSVENDGYSYWVFPVT---GISIMGVGALYWLLVV 497
+S W PV G++IM G + L V
Sbjct: 440 ----------FSLWSEPVVCGIGLAIMLTGVPVYFLGV 467
>Hs7657591 [E] KOG1287 Amino acid transporters
Length = 487
Score = 99.0 bits (245), Expect = 2e-20
Identities = 104/444 (23%), Positives = 185/444 (41%), Gaps = 55/444 (12%)
Query: 34 EHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLE 93
+ +L IS+IV IIG+GIF +P + + + +++G LI+W G+ G + E
Sbjct: 27 QKELGLISGISIIVGTIIGSGIFVSPKSVLS-NTEAVGPCLIIWAACGVLATLGALCFAE 85
Query: 94 FGLKIPKSGGEKNYLSRTL-PKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNS 152
G I KSGGE YL P P +L +A IV+ S + I L F+
Sbjct: 86 LGTMITKSGGEYPYLMEAYGPIPAYLFS--WASLIVIKPTS---------FAIICLSFSE 134
Query: 153 SLSETVIDKASRYIGSL---VIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSI 209
+ A Y+G +++ C +
Sbjct: 135 YVC------APFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIV 188
Query: 210 AIIAPN----LIEPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELE 265
AII + L + + NF NSF G+Q L +IS+A ++++ GW NY+ EEL
Sbjct: 189 AIIIISGLVLLAQGNTKNFDNSFE-GAQ-LSVGAISLAFYNGLWAYDGWNQLNYITEELR 246
Query: 266 DPRRTLMIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSL 325
+P R L +A + + L T YI + SY+ V+ E+ + ++ F +R+
Sbjct: 247 NPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQ-AVAVTFGDRV-------- 297
Query: 326 AMQIVSRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFPLTHLFSKLNYALFLH--- 382
+ S ++P + S G F+ R+ +EG H+ L+Y
Sbjct: 298 -LYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREG-----HMLKVLSYISVRRLTP 351
Query: 383 ----CFITIVVLLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTP 438
F I+ + G+I L ++ +++ + F + +GLI + +T ++ P
Sbjct: 352 APAIIFYGIIATIYIIPGDINSL-VNYFSFAAWLFYGLTILGLIVMRFTR----KELERP 406
Query: 439 WSSWYLVTVIFIISNLFLAVIPFV 462
++ V+ + ++FL + P +
Sbjct: 407 IKVPVVIPVLMTLISVFLVLAPII 430
>Hs19923170 [E] KOG1287 Amino acid transporters
Length = 507
Score = 95.9 bits (237), Expect = 1e-19
Identities = 94/431 (21%), Positives = 187/431 (42%), Gaps = 29/431 (6%)
Query: 34 EHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLE 93
+ + + +++IV IIG+GIF TP + S G++L++W G+F+ G Y E
Sbjct: 47 QRNITLLNGVAIIVGTIIGSGIFVTPTGVLK-EAGSPGLALVVWAACGVFSIVGALCYAE 105
Query: 94 FGLKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSS 153
G I KSGG+ Y+ ++ I+ + F Y++ L
Sbjct: 106 LGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCP 165
Query: 154 LSETVIDKASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIA 213
+ E +A++ + L ++ T + + A R + I
Sbjct: 166 VPE----EAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGK 221
Query: 214 PNLIEPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTLMI 273
++ N +FS LD +I +AL ++++ GW N+V EE+ +P R L +
Sbjct: 222 GDV-----SNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPL 276
Query: 274 AAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIVSRV 333
A +S+ + T +Y+ +Y+ + T ++S F Y + ++S +
Sbjct: 277 AIIISLPIVTLVYVLTNLAYFTTL------STEQMLSSEAVAVDFGNYH----LGVMSWI 326
Query: 334 LPFCIILSNYGNVMAVSFSNARVNQELAKEGIFP--LTHLFSKLNYALFLHCFITIVVLL 391
+P + LS +G+V F+++R+ ++EG P L+ + +L + F ++ LL
Sbjct: 327 IPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLL 386
Query: 392 LPPNGNIYQLIIDLYAYPSGWFN-LIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTVIFI 450
+ +I+ +I+ +++ FN L + + +I + W ++ P + V FI
Sbjct: 387 YAFSKDIFS-VINFFSF----FNWLCVALAIIGMIWLRHRK-PELERPIKVNLALPVFFI 440
Query: 451 ISNLFLAVIPF 461
++ LFL + F
Sbjct: 441 LACLFLIAVSF 451
>7302046 [E] KOG1287 Amino acid transporters
Length = 505
Score = 95.9 bits (237), Expect = 1e-19
Identities = 94/432 (21%), Positives = 186/432 (42%), Gaps = 41/432 (9%)
Query: 36 KLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFG 95
K++ + ++IV IIG+GIF +P + + S+ ++LI+WV+ G+F+ G Y E G
Sbjct: 48 KMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTG-SVNLALIVWVISGLFSMVGAYCYAELG 106
Query: 96 LKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSSLS 155
I KSG + Y+ T I IV + + F Y++ +
Sbjct: 107 TMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPECTPP 166
Query: 156 ETVIDKASRYIGSLVIISCTL---WHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAII 212
E ++R + I+ TL W + + T + II
Sbjct: 167 ED----SARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLAL-----------FIII 211
Query: 213 APNLIEPHWDNF-HNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTL 271
A + + + N + +F N + SI+++ ++++ GW N+++EEL+DP + L
Sbjct: 212 ATGVYQLYLGNTQYFTFENTDTKVT--SIALSFYSGLFAYNGWNYLNFIIEELKDPVKNL 269
Query: 272 MIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIVS 331
A +S L T +Y+ S+Y ++ E+ + ++ + ER F +++
Sbjct: 270 PRAIAISCTLVTIVYVMANVSFYTILSPDEVMGSS-AVAVTYAERAF---------GMLA 319
Query: 332 RVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFPLTHLFSKLNYALFLHCFITIVVLL 391
+P + LS +G V + +++R+ A G P + + + F T VL
Sbjct: 320 WTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMP--EILTMIQIQRFTP---TPAVLA 374
Query: 392 LPPNGNIYQLIIDLYA---YPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTVI 448
+ +Y + D++A Y L IG+ ++ + W N + P + ++
Sbjct: 375 MALLSMLYLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQPN-LPRPIRVPMVFPIV 433
Query: 449 FIISNLFLAVIP 460
++I+ +F+ V+P
Sbjct: 434 YLIATIFVTVVP 445
>CE28440 [E] KOG1287 Amino acid transporters
Length = 493
Score = 95.5 bits (236), Expect = 2e-19
Identities = 110/447 (24%), Positives = 196/447 (43%), Gaps = 61/447 (13%)
Query: 34 EHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLE 93
E + F+ +S+IV IIG+GIF +P I S+G+SLI+WVL G+F G Y E
Sbjct: 29 EKTMTLFNGVSIIVGCIIGSGIFISPTGI-QAQAGSVGLSLIVWVLSGLFAGIGAFCYAE 87
Query: 94 FGLKIPKSGGEKNYLSRT----LPKPKHLIECIYA----FTIVLLGFSSGNSYAFGKYII 145
G I KSGG+ Y+ L + IE I TIV L F+ I
Sbjct: 88 LGTLIRKSGGDYAYIMEAFGPFLAFLRLWIESIVVRPCTATIVALTFA-----------I 136
Query: 146 YVLG-FNSSLSETVIDKASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXX 204
Y+L F + ++ I +L+++ T + A +
Sbjct: 137 YMLKPFYPDCDSPPL--STELIAALLLVLLTAVNCISVKWASKVQDFFFVTKTAALVLII 194
Query: 205 XXXSIAIIAPNLIEPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEEL 264
+++ +D+F N F N ++ L+ + S+A +++++GW N+++EEL
Sbjct: 195 FTGLWNMVSGK--PEAFDSFENIFENTAKDLE--TASLAFYSGLFAYQGWNYLNFIVEEL 250
Query: 265 EDPRRTLMIAAPVSVGLTTFLY-IAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSK 323
++P+R L ++ +S L T +Y + V Y + P ++ + + +F E+ + +
Sbjct: 251 QNPKRNLPLSIAISCSLCTIIYTLTNVALYTSITPDEMLASPAVAV--LFAEKNYGWF-- 306
Query: 324 SLAMQIVSRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFPLTHLFSKLNY------ 377
+ +P + S G+ V +++R+ A+EG P ++ + +N
Sbjct: 307 -------AFCMPIFVACSTIGSANGVILTSSRLFYCGAREGQMP--NVLTMVNKTTKTPI 357
Query: 378 -ALFLHCFITIVVLLLPPNGNIYQLIIDLYAYPSGWFNLIIG---IGLIYIHWTNDGGWN 433
A+ L ++++ LLL + NIY LI Y S W + IG + L Y T
Sbjct: 358 PAVILTGLLSLLYLLL--SNNIYSLI--NYIQVSYW--IAIGGAILALFYFRKTMPDAPR 411
Query: 434 DIYTPWSSWYLVTVIFIISNLFLAVIP 460
+ P + +IF I + L ++P
Sbjct: 412 AVKAP----IVFPIIFFIGCVLLVLVP 434
>CE07028 [E] KOG1287 Amino acid transporters
Length = 464
Score = 89.0 bits (219), Expect = 2e-17
Identities = 101/433 (23%), Positives = 185/433 (42%), Gaps = 52/433 (12%)
Query: 36 KLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFG 95
+++ F+ ++I+ IIG+GIF +P + L S G+SL++W+L G+F G Y E G
Sbjct: 18 RISLFNGCTIIIGVIIGSGIFVSPKGVL-LEAGSAGMSLLIWLLSGVFAMIGAVCYSELG 76
Query: 96 LKIPKSGGEKNYLSRTL-PKPKHL-----IECIYAFTIVLLGFSSGNSYAFGKYIIYVLG 149
IPKSGG+ Y+ P P L + I ++ ++ + +YA +
Sbjct: 77 TLIPKSGGDYAYIYEAFGPLPSFLFLWVALVIINPTSLAIIAITCA-TYALQPF------ 129
Query: 150 FNSSLSETVIDK-ASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXS 208
++ + + V++ A I L I+C W + T
Sbjct: 130 YSCPVPDVVVNLFAGCIIAVLTFINC--WDVRMATRTNDFFTITKLIALTLIITCGGYWL 187
Query: 209 IAIIAPNLIEPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPR 268
NL+ P + GSQ +I++A ++SF G+ N+V EEL++P
Sbjct: 188 SLGHIDNLVMP-------DVAEGSQ-TKLSAIAMAFYSGVFSFSGFSYLNFVTEELKNPF 239
Query: 269 RTLMIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQ 328
R L A +S+ + T +Y+ + +Y+ V+ EI D+ ++ F ++I + + M
Sbjct: 240 RNLPRAIYISIPIVTIVYMLVNIAYFSVLTVDEILDSD-AVAITFADKILGTFGSKILMP 298
Query: 329 IVSRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFPLTHLFSKLNYALFLHCFITIV 388
+ + FS AR N +L + + + +FL +IV
Sbjct: 299 L-------------------MFFSGAR-NSQLPELFAMISIRQLTPIPSLIFLG-GTSIV 337
Query: 389 VLLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTVI 448
+L + GN++QL I+ ++ GL+ + +T + P L ++
Sbjct: 338 MLFI---GNVFQL-INYLSFAESLVVFSSVAGLLKLRFTMPENVLNA-RPIKISLLWPIL 392
Query: 449 FIISNLFLAVIPF 461
F + LFL ++PF
Sbjct: 393 FFLMCLFLLILPF 405
>CE27888 [E] KOG1287 Amino acid transporters
Length = 550
Score = 87.4 bits (215), Expect = 5e-17
Identities = 78/350 (22%), Positives = 146/350 (41%), Gaps = 26/350 (7%)
Query: 23 LISEDYIINPHEHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGI 82
+I E+ I HK+ S ++ IIG+GIF TPA I + SIG+SL++WVL +
Sbjct: 22 IIPENTQIMDESHKMGFLGATSYVIGNIIGSGIFITPASILR-NVDSIGLSLLIWVLCAV 80
Query: 83 FTFAGLSVYLEFGLKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSY---A 139
G Y+E G I ++G + Y+ + I + + VL+ + + +
Sbjct: 81 IAILGAICYIELGTSIREAGCDFAYICYV---KWYSIAFAFMWVSVLMTYPATIAICAET 137
Query: 140 FGKYIIYVLGFNSSLSETVIDKASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXX 199
FG+Y+I L + + ++ + ++ T W FF
Sbjct: 138 FGQYLIEGLKQYYEIDDALVPTCQKLFAYSLLFLVT-WMNFF------ELSKFAARFQIL 190
Query: 200 XXXXXXXXSIAIIAPNLIEPHWDNFHNSFSNGSQPLDW--YSISVALLQVIYSFKGWENA 257
+ II +H N Q + ++ + +++F GW+
Sbjct: 191 ATIAKLFSCMLIIGTGFYFYFVKGWHGYLENPMQGSKYGTGNLILGFYGGLWAFSGWDVL 250
Query: 258 NYVLEELEDPRRTLMIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERI 317
NY E++ P+R + A + + T +Y+AI +Y+VV+ + + + + I
Sbjct: 251 NYSTGEIKHPKRNVPFALLTGISVVTAIYVAINVAYFVVLDVETVKQSDAVAA------I 304
Query: 318 FERYSKSLAMQIVSRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFP 367
F R + + + V+PF I + G++ + FS +R A++G P
Sbjct: 305 FSRET----LGDFANVVPFLIGILLIGSLNSNLFSGSRYMYAAARQGHLP 350
>CE09028 [E] KOG1287 Amino acid transporters
Length = 566
Score = 87.4 bits (215), Expect = 5e-17
Identities = 78/350 (22%), Positives = 146/350 (41%), Gaps = 26/350 (7%)
Query: 23 LISEDYIINPHEHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGI 82
+I E+ I HK+ S ++ IIG+GIF TPA I + SIG+SL++WVL +
Sbjct: 22 IIPENTQIMDESHKMGFLGATSYVIGNIIGSGIFITPASILR-NVDSIGLSLLIWVLCAV 80
Query: 83 FTFAGLSVYLEFGLKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSY---A 139
G Y+E G I ++G + Y+ + I + + VL+ + + +
Sbjct: 81 IAILGAICYIELGTSIREAGCDFAYICYV---KWYSIAFAFMWVSVLMTYPATIAICAET 137
Query: 140 FGKYIIYVLGFNSSLSETVIDKASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXX 199
FG+Y+I L + + ++ + ++ T W FF
Sbjct: 138 FGQYLIEGLKQYYEIDDALVPTCQKLFAYSLLFLVT-WMNFF------ELSKFAARFQIL 190
Query: 200 XXXXXXXXSIAIIAPNLIEPHWDNFHNSFSNGSQPLDW--YSISVALLQVIYSFKGWENA 257
+ II +H N Q + ++ + +++F GW+
Sbjct: 191 ATIAKLFSCMLIIGTGFYFYFVKGWHGYLENPMQGSKYGTGNLILGFYGGLWAFSGWDVL 250
Query: 258 NYVLEELEDPRRTLMIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERI 317
NY E++ P+R + A + + T +Y+AI +Y+VV+ + + + + I
Sbjct: 251 NYSTGEIKHPKRNVPFALLTGISVVTAIYVAINVAYFVVLDVETVKQSDAVAA------I 304
Query: 318 FERYSKSLAMQIVSRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFP 367
F R + + + V+PF I + G++ + FS +R A++G P
Sbjct: 305 FSRET----LGDFANVVPFLIGILLIGSLNSNLFSGSRYMYAAARQGHLP 350
>CE22438 [E] KOG1287 Amino acid transporters
Length = 541
Score = 85.5 bits (210), Expect = 2e-16
Identities = 101/479 (21%), Positives = 200/479 (41%), Gaps = 57/479 (11%)
Query: 35 HKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEF 94
H++ + +S ++ IIG GIF TP + L+ + G++L++W+ G+ + G Y+E
Sbjct: 18 HQMGLWSCMSYVIANIIGAGIFITPGTVLKLALTN-GMALVVWLGCGLISLIGGICYIEL 76
Query: 95 GLKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSG---NSYAFGKYIIYVLGFN 151
G I G + Y + I + + V++ F + + FG+YI+ L
Sbjct: 77 GTSIRDPGCDFAY---NVYVGWEGIAFSFMWVGVIMSFPASAAVQAQTFGQYIVAGLSPI 133
Query: 152 SSLSETVIDKASRYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAI 211
L R +G +II T+ +++ S+AI
Sbjct: 134 WHLGSPYDVILERGLGFALIIILTVLNLY--------AIDKYASKFQIFVTIAKLLSLAI 185
Query: 212 IAPN-----LIEPHWDNFHNSFSN-GSQPLDWYSISVALLQVIYSFKGWENANYVLEELE 265
I +++ ++F ++F+ ++ D IS+A ++SF GW+ NY E++
Sbjct: 186 IIVTGFWYLIVKGETEHFKDAFTPLPNEKYDIGQISLAFYGALWSFAGWDILNYGTPEIK 245
Query: 266 DPRRTLMIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSL 325
+PRRT+ IA + T +Y+A+ SY V+ + ++ + + F RI
Sbjct: 246 NPRRTMPIALLGGISAVTLVYMAMNVSYMTVLDTETLKNSSAVAAD--FARI-------- 295
Query: 326 AMQIVSRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFP--LTHLFSKLN---YALF 380
+ S +PF I + G + + F +R A+EG P L+ + ++ N AL
Sbjct: 296 TLGDFSYAIPFMISILLIGTLNSNIFCGSRFTHAAAREGHLPTFLSCINAESNSPRAALL 355
Query: 381 LHCFITIVVLLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWND-IYTPW 439
TI V + I + ++ + L++I + N D I P
Sbjct: 356 FQLICTIAVTFVDTESLITYVTFVMFGQ-----RVFTMAALLWIRYRNIPVHPDAIRVP- 409
Query: 440 SSWYLVTVIFIISNLFLAVIPFVPPNGSVENDGYSYWVFPVTGISIMGVGALYWLLVVR 498
+ +++F + + L V PF+ + + G+ ++ +G L +++ ++
Sbjct: 410 ---LIFSILFFMITIALVVTPFIED-----------FTTTIVGVGLVLMGFLLYMIFMK 454
>CE03266 [E] KOG1287 Amino acid transporters
Length = 493
Score = 80.9 bits (198), Expect = 4e-15
Identities = 66/246 (26%), Positives = 119/246 (47%), Gaps = 24/246 (9%)
Query: 222 DNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTLMIAAPVSVGL 281
D+F N F N SQ D+ +S+A ++++ GW N+++EEL++P+R L +A +S+
Sbjct: 210 DSFENIFENTSQ--DFTKVSLAFYSGLFAYSGWNFLNFIVEELQNPKRNLPLAIAISITS 267
Query: 282 TTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIVSRVLPFCIILS 341
T +Y+ + Y I E+ ++ ++ +F +++ ++ + ++P C+ S
Sbjct: 268 CTVIYVLTNVALYTAISPDEMLESP-AVAVLFANKLYGKF---------AFIMPLCVACS 317
Query: 342 NYGNVMAVSFSNARVNQELAKEGIFP--LTHLFSKLNY---ALFLHCFITIVVLLLPPNG 396
G+ V F++AR+ A+EG P LT + K A+ L ++I LL +
Sbjct: 318 TIGSANGVIFTSARLFYSGAREGQMPAVLTMINKKTKTPIPAVILTGALSIAYLL--ASK 375
Query: 397 NIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTVIFIISNLFL 456
++YQLI Y S W L IG + + W D P + IF+ + L
Sbjct: 376 DVYQLI--NYIQISYW--LAIGTAIAALFWLR-RTMPDASRPIKVPLIWPAIFLAGCIAL 430
Query: 457 AVIPFV 462
+IP V
Sbjct: 431 VLIPMV 436
Score = 62.4 bits (150), Expect = 2e-09
Identities = 33/75 (44%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Query: 34 EHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLE 93
E L F+ +S+IV IIG+GIF +P + + S+G+SLI+W++ GIFT G Y E
Sbjct: 29 EKSLTLFNGVSMIVGCIIGSGIFVSPTGVQEQAG-SVGLSLIVWLISGIFTAIGAYCYAE 87
Query: 94 FGLKIPKSGGEKNYL 108
G I KSGG+ Y+
Sbjct: 88 LGTLIKKSGGDYAYI 102
>7292991 [E] KOG1287 Amino acid transporters
Length = 445
Score = 76.3 bits (186), Expect = 1e-13
Identities = 91/423 (21%), Positives = 172/423 (40%), Gaps = 49/423 (11%)
Query: 50 IIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFGLKIPKSGGEKNYLS 109
+IG+GIF +P+ + + S+G+S I+W+ G+ + G Y E G SG E Y
Sbjct: 1 MIGSGIFVSPSGLLVRTG-SVGVSFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAYFM 59
Query: 110 RTL-PKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSSLSETVIDKASRYIGS 168
P P L + T+VL + I L F E + + G
Sbjct: 60 DAYGPAPAFLFS--WVSTLVLKP---------SQMAIICLSFAQYAVEAFVTECDPPRGV 108
Query: 169 LVIISCT-LWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIAPNLIEPHWDNFHNS 227
+ +++ + I F I A L++ + + N+
Sbjct: 109 VKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAVVVVICGGAWKLMQGNTQHLSNA 168
Query: 228 FSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTLMIAAPVSVGLTTFLYI 287
F NG P + +I+ A ++++ GW N NYV EE+++P + L + + + L T Y
Sbjct: 169 F-NGPMP-NVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCYA 226
Query: 288 AIVFSYYVVIPKAEISDTGILISGVFFERIFERYSKSLAMQIVSRVLPFCIILSNYGNVM 347
I SY + E+ ++ ++ F RI + ++ ++P + +S +G+
Sbjct: 227 LINISYLAAMSPQEMIESE-AVAVTFGNRI---------LGALAWLMPLSVTISTFGSAN 276
Query: 348 AVSFSNARVNQELAKEGIFPLTHLFSKLNY----------ALFLHCFITIVVLLLPPNGN 397
F+ R+ ++EG HL L+Y L H I ++L +G
Sbjct: 277 GTLFAAGRLCFAASREG-----HLLDILSYVHVRRLTPAPGLIFHSLIASAMVL---HGT 328
Query: 398 IYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTVIFIISNLFLA 457
I L ID +++ + F + LI + +T + P+ ++ V+ ++ +++L
Sbjct: 329 IDSL-IDFFSFTAWIFYGGAMLALIVMRYTKP----NYPRPYKVPIIIPVVVLVISVYLV 383
Query: 458 VIP 460
P
Sbjct: 384 AAP 386
>7297908 [E] KOG1287 Amino acid transporters
Length = 500
Score = 75.5 bits (184), Expect = 2e-13
Identities = 68/284 (23%), Positives = 134/284 (46%), Gaps = 39/284 (13%)
Query: 239 SISVALLQVIYSFKGWENANYVLEELEDPRRTLMIAAPVSVGLTTFLYIAIVFSYYVVIP 298
+I A +++F GW N+V EEL+DP + L A +++ L T +Y+ + +Y+ V+
Sbjct: 230 NIGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAMPLVTSIYVLVNLAYFAVVN 289
Query: 299 KAEISDTGILISGVFFERIFERYSKSLAMQIVSRVLPFCIILSNYGNVMAVSFSNARVNQ 358
K E+ + + ++ F R+F ++ ++P + LS +G V V F++AR+
Sbjct: 290 KPEML-SSLAVAVTFGNRVFGP---------LAFMVPIFVALSTFGGVNGVLFTSARLFA 339
Query: 359 ELAKEG----IFPLTHLFSKLNY-ALFLHCFITIVVLLLPPNGNIYQLIIDLYAYPSGWF 413
A+EG F L H+ + +L C +++++LL N+YQLI Y W
Sbjct: 340 TGAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLLMLL---TDNVYQLI--NYFSSVLWL 394
Query: 414 NLIIGI-GLIYIHWTNDGGWNDIYTPWSSWYLVTVIFIISNLFLAVIPFV--PPNGSVEN 470
+++ I G++++ D+ P + + F++S + L ++P + P N
Sbjct: 395 SVVASIAGMLWLRHKRP----DLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQN----- 445
Query: 471 DGYSYWVFPVTGISIMGVGALYWLLVVRKSYSRYSSATHNNEVD 514
+ GI++ G+ Y+ + RK + N+ V+
Sbjct: 446 ------LLIGIGITLAGI-PFYYAFIARKKKPKCYGRLSNSVVE 482
Score = 56.6 bits (135), Expect = 9e-08
Identities = 29/75 (38%), Positives = 45/75 (59%), Gaps = 1/75 (1%)
Query: 34 EHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLE 93
+ KL + +++IV IIG+GIF P +F ++ S+G SL++W+ GI + G Y E
Sbjct: 38 KRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTE-SVGSSLLIWLTCGILSTIGALCYAE 96
Query: 94 FGLKIPKSGGEKNYL 108
G I +SGG+ YL
Sbjct: 97 LGTCITRSGGDYAYL 111
>CE07491 [E] KOG1287 Amino acid transporters
Length = 562
Score = 70.5 bits (171), Expect = 6e-12
Identities = 95/445 (21%), Positives = 174/445 (38%), Gaps = 47/445 (10%)
Query: 30 INPHEHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLS 89
+N + + F IIG GIF TP I + + G++L++W+ G+ + G
Sbjct: 30 LNVEQIDIQAFSMYMRFSANIIGAGIFITPGPILQYTFSN-GLALLVWIGCGLISLIGGI 88
Query: 90 VYLEFGLKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLG 149
Y+E G I G + Y T+ I + + V++ F + A + + +V G
Sbjct: 89 CYIELGTSIHDPGCDFAY---TVYVGWEGIAFSFMWVGVIMSFPAS---AAVQALTFVAG 142
Query: 150 FNSSLS-----ETVIDKASRYIGSLVIISCTLWHIF-FPTGAKRXXXXXXXXXXXXXXXX 203
+ +I+K +G +II T+ +++ A +
Sbjct: 143 MAPIWPLEHPWDGIIEKG---LGFALIIVLTILNLYAIDKYASKFQIVVTIAKMLSLAII 199
Query: 204 XXXXSIAIIAPNLIEPHWDNFHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEE 263
+I E F S +N Q IS+A ++SF GW+ N+ E
Sbjct: 200 IVTGFYYLIFKGQTEYLEHPFEGSNTNPGQ------ISLAFYGALWSFAGWDILNFGTPE 253
Query: 264 LEDPRRTLMIAAPVSVGLTTFLYIAIVFSYYVVIPKAEISDTGILISGVFFERIFERYSK 323
+ +PRRT+ IA V + T +Y+A+ SY V+ +I ++ + +
Sbjct: 254 IRNPRRTMPIALLGGVSIVTAVYLAMNISYMTVLTPGQIMNSTAVAADF----------A 303
Query: 324 SLAMQIVSRVLPFCIILSNYGNVMAVSFSNARVNQELAKEGIFP-----LTHLFSKLNYA 378
+ + S +PF I L G + + F +R A+EG P + + A
Sbjct: 304 QITLGGFSYAIPFMIALLLIGTLNSNIFCGSRFTHAAAREGHLPTFLSCINEESNSPRAA 363
Query: 379 LFLHCFITIVVLLLPPNGNIYQLIIDLYAYPSGWFNLIIGIGLIYIHWTNDGGWND-IYT 437
L T+VV + N +I+ ++ + L++I + N D I
Sbjct: 364 LLFQLVCTVVVTFIDTNS-----LINYVSFVMFGQRVFTMTALMWIRYRNIPVHPDAIRV 418
Query: 438 PWSSWYLVTVIFIISNLFLAVIPFV 462
P + + +F + + L V+PF+
Sbjct: 419 P----LIFSFLFWLITIALVVVPFI 439
>Hs20270383 [E] KOG1287 Amino acid transporters
Length = 470
Score = 68.6 bits (166), Expect = 2e-11
Identities = 96/429 (22%), Positives = 170/429 (39%), Gaps = 43/429 (10%)
Query: 44 SLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFGLKIPKSGG 103
S ++ IIG GIF +P + S ++G+SL +W I E + P SG
Sbjct: 20 SFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLCSAEISISFPCSGA 79
Query: 104 EKNYLSRTLPKPKHLIECIYAFTIVLLGFSSGNSYAFGKYIIYVLGFNSSLSETVIDKAS 163
+ +L R + ++ + G +G + +Y I F S S + K
Sbjct: 80 QYYFLKRYFGSTVAFLN-LWTSLFLGSGVVAGQALLLAEYSIQP--FFPSCSVPKLPKKC 136
Query: 164 RYIGSLVIISCTLWHIFFPTGAKRXXXXXXXXXXXXXXXXXXXXSIAIIAPNLIEPHWDN 223
+ L I+ I G K ++ LI +N
Sbjct: 137 LALAMLWIVG-----ILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVF--LIRGKKEN 189
Query: 224 ---FHNSFSNGSQPLDWYSISVALLQVIYSFKGWENANYVLEELEDPRRTLMIAAPVSVG 280
F N+F ++ D + A+ Q +++ G + EL+ PR T+ ++
Sbjct: 190 VERFQNAFD--AELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALP 247
Query: 281 LTTFLYIAIVFSYYVVI-PKAEISDTGILISGVFFERIFERYSKSLAMQIVSRVLPFCII 339
L T +Y+ + SY V+ P+ +S + I+ +R SLA ++PF I
Sbjct: 248 LMTVVYLLVNISYLTVLTPREILSSDAVAITWA------DRAFPSLAW-----IMPFAIS 296
Query: 340 LSNYGNVMAVSFSNARVNQELAKEGIFPLTHLFSKLNYALFLHCFITIVVLLLPPNGN-- 397
S + N++ F ++R ++EG PL LF+ LN H VLLL G+
Sbjct: 297 TSLFSNLLISIFKSSRPIYLASQEGQLPL--LFNTLN----SHSSPFTAVLLLVTLGSLA 350
Query: 398 -IYQLIIDLYAY---PSGWFNLIIGIGLIYIHWTNDGGWNDIYTPWSSWYLVTVIFIISN 453
I +IDL Y +++++ IG++ + ++ P+ + + I+ +
Sbjct: 351 IILTSLIDLINYIFFTGSLWSILLMIGILRRRYQEP----NLSIPYKVFLSFPLATIVID 406
Query: 454 LFLAVIPFV 462
+ L VIP V
Sbjct: 407 VGLVVIPLV 415
>CE17868 [E] KOG1287 Amino acid transporters
Length = 662
Score = 61.2 bits (147), Expect = 4e-09
Identities = 48/188 (25%), Positives = 88/188 (46%), Gaps = 20/188 (10%)
Query: 223 NFHNSFSNGSQPLDWY--SISVALLQVIYSFKGWENANYVLEELEDPRRTLMIAAPVSVG 280
NF NSF+ DW ++ + + ++++ GW+ N+ EE+E+PRRTL IAA +
Sbjct: 352 NFKNSFTGS----DWNPGNLVLGVYSGLFAYNGWDVLNFGAEEIENPRRTLPIAAISGIA 407
Query: 281 LTTFLYIAIVFSYYVVIPKAEISDT-GILISGVFFERIFERYSKSLAMQIVSRVLPFCII 339
++ ++I + SY+ V+ + ++ + + FF ER + +PF I
Sbjct: 408 ISATVFILMNVSYFSVLSVEDFKNSPAVAVVRTFFITFAER-----TLGDFHYAIPFLIS 462
Query: 340 LSNYGNVMAVSFSNARVNQELAKEGIFP-----LTHLFSKLNYALFLHCFITIVVLLLPP 394
L G++ F+ +R A++ + P + H A+F I I + +
Sbjct: 463 LLLIGSMNTTIFACSRYMYSGAQQSVMPTPLRGIHHRTRSPRLAVFAEILIAICLSFI-- 520
Query: 395 NGNIYQLI 402
GN+ QLI
Sbjct: 521 -GNLDQLI 527
Score = 52.8 bits (125), Expect = 1e-06
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Query: 32 PHEHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVY 91
P +H + IS V I+G+GIF +P I + S+G+SL LW L + G Y
Sbjct: 9 PQKHTIGLITAISYTVGDIVGSGIFISPTSILNHAG-SVGLSLCLWALCACISLFGALSY 67
Query: 92 LEFGLKIPKSGGEKNYLS 109
+E G I KSG + YLS
Sbjct: 68 VELGTSIRKSGCDFAYLS 85
>CE17028 [E] KOG1287 Amino acid transporters
Length = 521
Score = 51.2 bits (121), Expect = 4e-06
Identities = 39/122 (31%), Positives = 58/122 (46%), Gaps = 15/122 (12%)
Query: 34 EHKLNTFHTISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLE 93
++K+ S IV IIG+GIF P I + S+G+SLI+WV + Y+E
Sbjct: 6 DNKIGLIGATSYIVGSIIGSGIFIAPKGIVEHAG-SVGLSLIIWVFCALLNMITAINYIE 64
Query: 94 FGLKIPKSGGEKNYLSRTLPKPKHLIECIYAFTIVLLG--FSSGNSYA-----FGKYIIY 146
G IP+SG + Y+ P AF+++ L S +S A FGKY++
Sbjct: 65 LGTSIPESGADLAYIDYMGWTP-------IAFSLLWLSLLIQSSSSAAVLYLTFGKYLVQ 117
Query: 147 VL 148
L
Sbjct: 118 AL 119
>CE06416 [E] KOG1287 Amino acid transporters
Length = 440
Score = 51.2 bits (121), Expect = 4e-06
Identities = 37/156 (23%), Positives = 75/156 (47%), Gaps = 17/156 (10%)
Query: 243 ALLQVIYSFKGWENANYVLEELEDPRRTLMIAAPVSVGLTTFLYIAIVFSYYVVI-PKAE 301
AL ++S+ GW+ N+ EE+E+P+RT+ ++ + + +Y+A+ +Y +V+ P
Sbjct: 135 ALFAGLFSYDGWDILNFGAEEIENPKRTMPLSIIIGMTCIGVIYVAVNVAYSIVLSPTEM 194
Query: 302 ISDTGILISGVFFERIFERYSKSLAMQIVSRVLPFCIILSNYGNVMAVSFSNARVNQELA 361
I+ + I + +K+L + V+P + + G++ + FS +R Q ++
Sbjct: 195 IASNAVAI---------DFANKTLG--AAAFVVPVMVAILLIGSLNSTMFSASRYLQAVS 243
Query: 362 KEGIFP-----LTHLFSKLNYALFLHCFITIVVLLL 392
++G P + AL +H I I V L
Sbjct: 244 RQGHIPSAISGIAPNCDSPRVALLVHILIAIAVSFL 279
>Hs13654280 [E] KOG1287 Amino acid transporters
Length = 180
Score = 50.4 bits (119), Expect = 6e-06
Identities = 25/66 (37%), Positives = 39/66 (58%), Gaps = 1/66 (1%)
Query: 43 ISLIVNRIIGTGIFSTPALIFTLSQQSIGISLILWVLGGIFTFAGLSVYLEFGLKIPKSG 102
+++IV I+G+GIF TP + S G++L++W G+F+ G Y E G I KSG
Sbjct: 56 VAVIVVAIMGSGIFVTPTGVLK-EAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSG 114
Query: 103 GEKNYL 108
G+ Y+
Sbjct: 115 GDYAYM 120
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.142 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,476,654
Number of Sequences: 60738
Number of extensions: 1304023
Number of successful extensions: 3665
Number of sequences better than 1.0e-05: 27
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3594
Number of HSP's gapped (non-prelim): 55
length of query: 519
length of database: 30,389,216
effective HSP length: 111
effective length of query: 408
effective length of database: 23,647,298
effective search space: 9648097584
effective search space used: 9648097584
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)