ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2032 good T KOG0211 Signal transduction mechanisms Protein phosphatase 2A regulatory subunit A and related proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2032 727832 729661 610
(610 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YAL016w [T] KOG0211 Protein phosphatase 2A regulatory subunit A ... 869 0.0
SPAP8A3.09c [T] KOG0211 Protein phosphatase 2A regulatory subuni... 523 e-148
At3g25800 [T] KOG0211 Protein phosphatase 2A regulatory subunit ... 489 e-138
At1g25490 [T] KOG0211 Protein phosphatase 2A regulatory subunit ... 466 e-131
Hs11386167 [T] KOG0211 Protein phosphatase 2A regulatory subunit... 452 e-127
Hs21361399 [T] KOG0211 Protein phosphatase 2A regulatory subunit... 452 e-127
HsM7657475 [T] KOG0211 Protein phosphatase 2A regulatory subunit... 449 e-126
At1g13320 [T] KOG0211 Protein phosphatase 2A regulatory subunit ... 442 e-124
7297392 [T] KOG0211 Protein phosphatase 2A regulatory subunit A ... 442 e-124
CE01957 [T] KOG0211 Protein phosphatase 2A regulatory subunit A ... 422 e-118
Hs4826934 [T] KOG0211 Protein phosphatase 2A regulatory subunit ... 57 1e-07
CE20811 [T] KOG0211 Protein phosphatase 2A regulatory subunit A ... 54 7e-07
Hs14728229 [T] KOG1240 Protein kinase containing WD40 repeats 52 3e-06
>YAL016w [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 635
Score = 869 bits (2246), Expect = 0.0
Identities = 432/606 (71%), Positives = 526/606 (86%), Gaps = 1/606 (0%)
Query: 4 NSDSKVNLYPLALLMDELKHDDISNRVEAMKKLDTIALALGVQRTRDELIPFLTEVAQDD 63
+SDS +LYPLALLMDELKHDDI+NRVEAMKKLDTIALALG +RTR+ELIPFLTEVAQDD
Sbjct: 29 DSDSNESLYPLALLMDELKHDDIANRVEAMKKLDTIALALGPERTRNELIPFLTEVAQDD 88
Query: 64 EDEVFAVLAEQLGNFVPFVGGRKYATLLLPALEILASTEETLVREKAVDSLNMVAEQLTE 123
EDEVFAVLAEQLG FVP++GG +YAT+LLP LEILAS EETLVREKAVDSLN VA++L++
Sbjct: 89 EDEVFAVLAEQLGKFVPYIGGPQYATILLPVLEILASAEETLVREKAVDSLNNVAQELSQ 148
Query: 124 EQLLHDFVPLIENLATNEWFSSKVSACGLFKAVFVRIQDDKFRKDLLSLFLQLIQDDTPM 183
EQL DFVPLIE+LAT +WFSSKVSACGLFK+V VRI+DD RK++L+L+LQL QDDTPM
Sbjct: 149 EQLFSDFVPLIEHLATADWFSSKVSACGLFKSVIVRIKDDSLRKNILALYLQLAQDDTPM 208
Query: 184 VRRAAGRNLPTLVDQLTEHPELSTDDEWDYISSMFQRLVNDSQDSVKFLAVDVLISILKF 243
V+RA G+NLP L+D LT++ LSTD++WDYIS++FQ+++ND+QDSVKFLAVD LISILKF
Sbjct: 209 VKRAVGKNLPILIDLLTQNLGLSTDEDWDYISNIFQKIINDNQDSVKFLAVDCLISILKF 268
Query: 244 FNKKKDFTHTKDLLQSSIQLIGDEAWRVRYMAADRFEELASQFVSNPQYVSELLEPFLAL 303
FN K D +HT+DLL S+++LIGDEAWRVRYMAADRF +LASQF SN Y+ EL++PFL L
Sbjct: 269 FNAKGDESHTQDLLNSAVKLIGDEAWRVRYMAADRFSDLASQFSSNQAYIDELVQPFLNL 328
Query: 304 CQDNESDVRKAIAKQIPGYAKLLNDPSVILNRIIPAAQNLSIDETECVRASLALEITNLA 363
C+DNE DVR+A+AKQ+ G+AK LNDPS+ILN+I+PA QNLS+DE+E VR++LA +ITN+
Sbjct: 329 CEDNEGDVREAVAKQVSGFAKFLNDPSIILNKILPAVQNLSMDESETVRSALASKITNIV 388
Query: 364 PLLPKQDSMDSLVPILLHMLKDEFPDVRLNIIAKLKIVNESVGIEFLSENLLPAITELAK 423
LL K +++ +PILL+ML+DEFPDVRLNIIA LK+VN+ +GIE LS++LLPAITELAK
Sbjct: 389 LLLNKDQVINNFLPILLNMLRDEFPDVRLNIIASLKVVNDVIGIELLSDSLLPAITELAK 448
Query: 424 DPNWRVRLAIIEYIPLLAEQLGMEFFDSKLSDLCLSWLWDGVYSIRSAAITNLSKLTEIF 483
D NWRVR+AIIEYIP+LAEQLGM+FFD +LSDLCLSWLWD VYSIR AA+ NL +LTEIF
Sbjct: 449 DVNWRVRMAIIEYIPILAEQLGMQFFDQQLSDLCLSWLWDTVYSIREAAVNNLKRLTEIF 508
Query: 484 GSDWAQEEIISRLLKSDTQLLENFNYRITLLFALTGLVPVVSTDVVVEKILPFVNHLSTD 543
GSDW ++EIISRLLK D QLLENF R T+L ALT LVPVVS DVV E++LPF++HL+ D
Sbjct: 509 GSDWCRDEIISRLLKFDLQLLENFVSRFTILSALTTLVPVVSLDVVTEQLLPFISHLADD 568
Query: 544 NVPNIRFNVAKFYAVIVEALTKNTNKNHIELINNTIIPTLEKLCQDPDVDVRFFSAQSLE 603
VPNIRFNVAK YAVIV+ L K+ K + LI NTI+P+L+ LCQD DVDV++F+ +SL
Sbjct: 569 GVPNIRFNVAKSYAVIVKVLIKDEAK-YDALIKNTILPSLQTLCQDEDVDVKYFAKKSLA 627
Query: 604 KCKSFL 609
+C+ L
Sbjct: 628 ECQELL 633
>SPAP8A3.09c [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 590
Score = 523 bits (1348), Expect = e-148
Identities = 290/602 (48%), Positives = 405/602 (67%), Gaps = 19/602 (3%)
Query: 5 SDSKVN-LYPLALLMDELKHDDISNRVEAMKKLDTIALALGVQRTRDELIPFLTEVAQDD 63
++++VN LYP+A+L+DELKHD+I+ R+ A+++L TIALALG +RTRDELIPFL E + DD
Sbjct: 3 TENQVNDLYPIAVLIDELKHDEITYRLNALERLSTIALALGPERTRDELIPFLDE-SIDD 61
Query: 64 EDEVFAVLAEQLGNFVPFVGGRKYATLLLPALEILASTEETLVREKAVDSLNMVAEQLTE 123
EDEV + LA+QLGNFV +VGG +YA +LL LE LA+TEET+VR+KAVDSLN V L++
Sbjct: 62 EDEVLSALADQLGNFVDYVGGPEYAHVLLSPLENLAATEETVVRDKAVDSLNKVCICLSQ 121
Query: 124 EQLLHDFVPLIENLATNEWFSSKVSACGLFKAVFVRIQDDKFRKDLLSLFLQLIQDDTPM 183
EQL FVPL++ L+T EWF+S+ S+ GL+ A + + ++ + L F L D+ PM
Sbjct: 122 EQLEQYFVPLVQRLSTAEWFTSRASSAGLYCAAYSQSENPAVKVSLRQSFSHLCHDEAPM 181
Query: 184 VRRAAGRNLPTLVDQLTEHPELSTDDEWDYISSMFQRLVNDSQDSVKFLAVDVLISILKF 243
VRR A N V +T+ + D +F L ND QDSV+ L+ D+++S+ +
Sbjct: 182 VRRPAATNCAKFVFLVTKQEAI------DEFIPLFNSLSNDDQDSVRLLSFDIMVSLAEV 235
Query: 244 FNKKKDFTHTKDLLQSSIQLIGDEAWRVRYMAADRFEELASQFVSNPQYVS-ELLEPFLA 302
+ H LLQ + D +WR RYM A F +LA V P + EL++PF+
Sbjct: 236 LKSDSEIRHY--LLQPLRSFVSDSSWRTRYMVAANFVKLAK--VVGPSLIKDELIKPFVL 291
Query: 303 LCQDNESDVRKAIAKQIPGYAKLLNDPSVILNRIIPAAQNLSIDETECVRASLALEITNL 362
L +D E +VR+AIA QIPG+ +LL D ++L IIP Q L D + VRA+L + I L
Sbjct: 292 LMKDTEQEVRRAIATQIPGFCELL-DKRIVLEEIIPVIQELINDPAQHVRAALGMNIGAL 350
Query: 363 APLLPKQDSMDSLVPILLHMLKDEFPDVRLNIIAKLKIVNESVGIEFLSENLLPAITELA 422
AP L K+ + + L+P+ L +LKDE P+VRLNII+KL++VN+ VGIE LS++LLPAI LA
Sbjct: 351 APQLGKEKTTEYLLPMFLELLKDENPEVRLNIISKLEVVNKVVGIELLSQSLLPAIVTLA 410
Query: 423 KDPNWRVRLAIIEYIPLLAEQLGMEFFDSKLSDLCLSWLWDGVYSIRSAAITNLSKLTEI 482
+D WRVRLAII+YIPLLA+QLG+EFF+ K+ +LC+SWL D VYSIR AAI NL KLTEI
Sbjct: 411 EDKQWRVRLAIIDYIPLLAQQLGVEFFNEKMGNLCMSWLEDHVYSIREAAIKNLRKLTEI 470
Query: 483 FGSDWAQEEIISRLLKSDTQLLENFNYRITLLFALTGLVPVVSTDVVVEKILPFVNHLST 542
FG +WA E II + L + N+ YR+T +FA++ + P ++ +V+ ++ILP + L
Sbjct: 471 FGLEWATETIIPKFLAMRSH--PNYLYRMTTIFAISEIAPALNAEVIEKQILPTLEQLVN 528
Query: 543 DNVPNIRFNVAKFYAVIVEALTKNTNKNHIELINNTIIPTLEKLCQDPDVDVRFFSAQSL 602
D +PNIRFNVAK + V+ L + E IIP LE+L +D D DV++F+ Q+L
Sbjct: 529 DPIPNIRFNVAKAFEVLKPVLAAGGDSTVYE---QQIIPLLEQLTKDNDPDVQYFATQAL 585
Query: 603 EK 604
E+
Sbjct: 586 EQ 587
Score = 61.6 bits (148), Expect = 3e-09
Identities = 90/412 (21%), Positives = 159/412 (37%), Gaps = 75/412 (18%)
Query: 46 QRTRDELIPFLTEVAQDDED-------EVFAVLAEQLGNFVPFVGGRKYATLLLPALEIL 98
Q DE IP ++ DD+D ++ LAE L + R Y LL P +
Sbjct: 200 QEAIDEFIPLFNSLSNDDQDSVRLLSFDIMVSLAEVLKSDSEI---RHY--LLQPLRSFV 254
Query: 99 ASTE---ETLVREKAVDSLNMVAEQLTEEQLLHDFVPLIENLATNEWFSSKVSACGLFKA 155
+ + +V V +V L +++L+ FV L+++ + G +
Sbjct: 255 SDSSWRTRYMVAANFVKLAKVVGPSLIKDELIKPFVLLMKDTEQEVRRAIATQIPGFCEL 314
Query: 156 VFVRIQDDKFRKDLLSLFLQLIQDDTPMVRRAAGRNLPTLVDQLTEHPELSTDDEWDYIS 215
+ RI ++++ + +LI D VR A G N+ L P+L + +Y+
Sbjct: 315 LDKRI----VLEEIIPVIQELINDPAQHVRAALGMNIGALA------PQLGKEKTTEYLL 364
Query: 216 SMFQRLVNDSQDSVKFLAVDVLISILKFFNKKKDFTH-TKDLLQSSIQLIGDEAWRVRYM 274
MF L+ D V+ +IS L+ NK ++ LL + + L D+ WRVR
Sbjct: 365 PMFLELLKDENPEVRLN----IISKLEVVNKVVGIELLSQSLLPAIVTLAEDKQWRVRLA 420
Query: 275 AADRFEELASQFVSNPQYVSELLEPF-LALCQDNESDVRKAIAKQ--------------- 318
D LA Q ++ +E + ++ +D+ +R+A K
Sbjct: 421 IIDYIPLLAQQL--GVEFFNEKMGNLCMSWLEDHVYSIREAAIKNLRKLTEIFGLEWATE 478
Query: 319 --IPGYAKLLNDPS---------------------VILNRIIPAAQNLSIDETECVRASL 355
IP + + + P+ VI +I+P + L D +R ++
Sbjct: 479 TIIPKFLAMRSHPNYLYRMTTIFAISEIAPALNAEVIEKQILPTLEQLVNDPIPNIRFNV 538
Query: 356 ALEITNLAPLLPKQDSM----DSLVPILLHMLKDEFPDVRLNIIAKLKIVNE 403
A L P+L ++P+L + KD PDV+ L+ N+
Sbjct: 539 AKAFEVLKPVLAAGGDSTVYEQQIIPLLEQLTKDNDPDVQYFATQALEQTND 590
>At3g25800 [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 587
Score = 489 bits (1259), Expect = e-138
Identities = 272/593 (45%), Positives = 389/593 (64%), Gaps = 22/593 (3%)
Query: 11 LYPLALLMDELKHDDISNRVEAMKKLDTIALALGVQRTRDELIPFLTEVAQDDEDEVFAV 70
LYP+A+L+DELK+DDI R+ ++++L TIA ALG +RTR ELIPFL+E DD+DEV
Sbjct: 8 LYPIAVLIDELKNDDIQLRLNSIRRLSTIARALGEERTRKELIPFLSE-NNDDDDEVLLA 66
Query: 71 LAEQLGNFVPFVGGRKYATLLLPALEILASTEETLVREKAVDSLNMVAEQLTEEQLLHDF 130
+AE+LG F+P+VGG +YA +LLP LE L++ EET VREKAV+SL V Q+ E L+ F
Sbjct: 67 MAEELGVFIPYVGGVEYAHVLLPPLETLSTVEETCVREKAVESLCRVGSQMRESDLVDHF 126
Query: 131 VPLIENLATNEWFSSKVSACGLFKAVFVRIQDDKFRKDLLSLFLQLIQDDTPMVRRAAGR 190
+ L++ LA EWF+++VSACG+F + D + +L SL+ QL QDD PMVRRAA
Sbjct: 127 ISLVKRLAAGEWFTARVSACGVFHIAYPSAPD-MLKTELRSLYTQLCQDDMPMVRRAAAT 185
Query: 191 NLPTLVDQLTEHPELSTDDEWDYISSMFQRLVNDSQDSVKFLAVDVLISILKFFNKKKDF 250
NL + E L TD + SMF+ L D QDSV+ LAV+ ++ K +
Sbjct: 186 NLGKFAATV-ESAHLKTD-----VMSMFEDLTQDDQDSVRLLAVEGCAALGKLLEPQDCV 239
Query: 251 THTKDLLQSSIQLIGDEAWRVRYMAADRFEELASQFVSNPQYVSELLEPFLALCQDNESD 310
H +L + D++WRVRYM A++ EL P +EL+ ++ L +DNE++
Sbjct: 240 QH---ILPVIVNFSQDKSWRVRYMVANQLYELCEAVGPEPTR-TELVPAYVRLLRDNEAE 295
Query: 311 VRKAIAKQIPGYAKLLNDPSVILNRIIPAAQNLSIDETECVRASLALEITNLAPLLPKQD 370
VR A A ++ + ++LN P + + I+P + LS D ++ VR++LA I +AP+L K
Sbjct: 296 VRIAAAGKVTKFCRILN-PEIAIQHILPCVKELSSDSSQHVRSALASVIMGMAPVLGKDA 354
Query: 371 SMDSLVPILLHMLKDEFPDVRLNIIAKLKIVNESVGIEFLSENLLPAITELAKDPNWRVR 430
+++ L+PI L +LKDEFPDVRLNII+KL VN+ +GI+ LS++LLPAI ELA+D +WRVR
Sbjct: 355 TIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVR 414
Query: 431 LAIIEYIPLLAEQLGMEFFDSKLSDLCLSWLWDGVYSIRSAAITNLSKLTEIFGSDWAQE 490
LAIIEYIPLLA QLG+ FFD KL LC+ WL D V+SIR AA NL +L E FG +WA +
Sbjct: 415 LAIIEYIPLLASQLGVGFFDDKLGALCMQWLQDKVHSIRDAAANNLKRLAEEFGPEWAMQ 474
Query: 491 EIISRLLKSDTQLLENFNYRITLLFALTGLVPVVSTDVVVEKILPFVNHLSTDNVPNIRF 550
I+ ++L+ ++ YR+T+L A++ L PV+ +++ K+LP V S D VPNI+F
Sbjct: 475 HIVPQVLEMVNN--PHYLYRMTILRAVSLLAPVMGSEITCSKLLPVVMTASKDRVPNIKF 532
Query: 551 NVAKFYAVIVEALTKNTNKNHIELINNTIIPTLEKLCQDPDVDVRFFSAQSLE 603
NVAK ++ + ++ ++ TI P L +L +DPDVDVRFF+ Q+L+
Sbjct: 533 NVAKVLQSLIPIVDQS-------VVEKTIRPGLVELSEDPDVDVRFFANQALQ 578
>At1g25490 [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 588
Score = 466 bits (1198), Expect = e-131
Identities = 262/592 (44%), Positives = 383/592 (64%), Gaps = 22/592 (3%)
Query: 11 LYPLALLMDELKHDDISNRVEAMKKLDTIALALGVQRTRDELIPFLTEVAQDDEDEVFAV 70
LYP+A+L+DELK+DDI R+ ++++L TIA ALG +RTR ELIPFL+E + DD+DEV
Sbjct: 8 LYPIAVLIDELKNDDIQLRLNSIRRLSTIARALGEERTRKELIPFLSENS-DDDDEVLLA 66
Query: 71 LAEQLGNFVPFVGGRKYATLLLPALEILASTEETLVREKAVDSLNMVAEQLTEEQLLHDF 130
+AE+LG F+PFVGG ++A +LLP LE L + EET VREKAV+SL + Q+ E L+ F
Sbjct: 67 MAEELGVFIPFVGGIEFAHVLLPPLESLCTVEETCVREKAVESLCKIGSQMKENDLVESF 126
Query: 131 VPLIENLATNEWFSSKVSACGLFKAVFVRIQDDKFRKDLLSLFLQLIQDDTPMVRRAAGR 190
VPL++ LA EWF+++VSACG+F + D + +L + + QL +DD PMVRRAA
Sbjct: 127 VPLVKRLAGGEWFAARVSACGIFHVAYQGCTD-VLKTELRATYSQLCKDDMPMVRRAAAS 185
Query: 191 NLPTLVDQLTEHPELSTDDEWDYISSMFQRLVNDSQDSVKFLAVDVLISILKFFNKKKDF 250
NL + E L + I +MF L D QDSV+ LAV+ ++ K +
Sbjct: 186 NLGKFATTV-ESTFLIAE-----IMTMFDDLTKDDQDSVRLLAVEGCAALGKLLEPQDCV 239
Query: 251 THTKDLLQSSIQLIGDEAWRVRYMAADRFEELASQFVSNPQYVSELLEPFLALCQDNESD 310
+L + D++WRVRYM A++ EL + V ++L+ ++ L +DNE++
Sbjct: 240 AR---ILPVIVNFSQDKSWRVRYMVANQLYELC-EAVGPDCTRTDLVPAYVRLLRDNEAE 295
Query: 311 VRKAIAKQIPGYAKLLNDPSVILNRIIPAAQNLSIDETECVRASLALEITNLAPLLPKQD 370
VR A A ++ + +LLN P + + I+P + LS D ++ VR++LA I +AP+L K
Sbjct: 296 VRIAAAGKVTKFCRLLN-PELAIQHILPCVKELSSDSSQHVRSALASVIMGMAPILGKDS 354
Query: 371 SMDSLVPILLHMLKDEFPDVRLNIIAKLKIVNESVGIEFLSENLLPAITELAKDPNWRVR 430
+++ L+PI L +LKDEFPDVRLNII+KL VN+ +GI+ LS++LLPAI ELA+D +WRVR
Sbjct: 355 TIEHLLPIFLSLLKDEFPDVRLNIISKLDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVR 414
Query: 431 LAIIEYIPLLAEQLGMEFFDSKLSDLCLSWLWDGVYSIRSAAITNLSKLTEIFGSDWAQE 490
LAIIEY+PLLA QLG+ FFD KL LC+ WL D VYSIR AA NL +L E FG +WA +
Sbjct: 415 LAIIEYVPLLASQLGIGFFDDKLGALCMQWLQDKVYSIREAAANNLKRLAEEFGPEWAMQ 474
Query: 491 EIISRLLKSDTQLLENFNYRITLLFALTGLVPVVSTDVVVEKILPFVNHLSTDNVPNIRF 550
++ ++L D ++ +R+ +L A++ + PV+ +++ K LP V S D VPNI+F
Sbjct: 475 HLVPQVL--DMVNNPHYLHRMMVLRAISLMAPVMGSEITCSKFLPVVVEASKDRVPNIKF 532
Query: 551 NVAKFYAVIVEALTKNTNKNHIELINNTIIPTLEKLCQDPDVDVRFFSAQSL 602
NVAK ++ + ++ +++ TI L L +DPDVDVR+F+ Q+L
Sbjct: 533 NVAKLLQSLIPIVDQS-------VVDKTIRQCLVDLSEDPDVDVRYFANQAL 577
>Hs11386167 [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 601
Score = 452 bits (1164), Expect = e-127
Identities = 262/605 (43%), Positives = 379/605 (62%), Gaps = 29/605 (4%)
Query: 2 GDNSDSKVNLYPLALLMDELKHDDISNRVEAMKKLDTIALALGVQRTRDELIPFLTEVAQ 61
GD DS LYP+A+L+DEL+++D+ R+ ++KKL TIALALGV+RTR EL+PFLT+
Sbjct: 16 GDGDDS---LYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY 72
Query: 62 DDEDEVFAVLAEQLGNFVPFVGGRKYATLLLPALEILASTEETLVREKAVDSLNMVAEQL 121
D EDEV LAEQLGNF VGG +A LLP LE LA+ EET+VR+KAV+SL ++++
Sbjct: 73 D-EDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEH 131
Query: 122 TEEQLLHDFVPLIENLATNEWFSSKVSACGLFKAVFVRIQDDKFRKDLLSLFLQLIQDDT 181
T L FVPL++ LA+ +WF+S+ SACGLF + R + + ++ F L DDT
Sbjct: 132 TPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASN-AVKAEIRQQFRSLCSDDT 190
Query: 182 PMVRRAAGRNLPTLVDQLTEHPELSTDDEWDYISSMFQRLVNDSQDSVKFLAVDVLISIL 241
PMVRRAA L L D I +F L +D QDSV+ LAV+ +SI
Sbjct: 191 PMVRRAAASKLGEFAKVL------ELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIA 244
Query: 242 KFFNKKKDFTHTKDLLQSSIQLIGDEAWRVRYMAADRFEELASQFVSNPQY-VSELLEPF 300
+ ++ T L+ + + D++WRVRYM ADRF EL Q P+ +++L+ F
Sbjct: 245 QLLSQDDLETLVMPTLRQAAE---DKSWRVRYMVADRFSEL--QKAMGPKITLNDLIPAF 299
Query: 301 LALCQDNESDVRKAIAKQIPGYAKLL---NDPSVILNRIIPAAQNLSIDETECVRASLAL 357
L +D E++VR A A ++ + L + ++I+N+I+P + L D + V+++LA
Sbjct: 300 QNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALAS 359
Query: 358 EITNLAPLLPKQDSMDSLVPILLHMLKDEFPDVRLNIIAKLKIVNESVGIEFLSENLLPA 417
I L+ +L K+++++ L+P+ L LKDE PDVRLNII+ L VNE +GI LS++LLPA
Sbjct: 360 VIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPA 419
Query: 418 ITELAKDPNWRVRLAIIEYIPLLAEQLGMEFFDSKLSDLCLSWLWDGVYSIRSAAITNLS 477
I ELA+D WRVRLAIIEY+PLLA QLG+EFFD KL+ LC++WL D VY+IR AA NL
Sbjct: 420 IVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLM 479
Query: 478 KLTEIFGSDWAQEEIISRLLKSDTQLLENFNYRITLLFALTGLVPVVSTDVVVEKILPFV 537
KL + FG++WAQ I+ ++L N+ +R+T LF + L ++ +++LP V
Sbjct: 480 KLVQKFGTEWAQNTIVPKVLVMAND--PNYLHRMTTLFCINALSEACGQEITTKQMLPIV 537
Query: 538 NHLSTDNVPNIRFNVAKFYAVIVEALTKNTNKNHIELINNTIIPTLEKLCQDPDVDVRFF 597
++ D V N+RFNVAK I L N + ++ P L+KL QD D+DV++F
Sbjct: 538 LKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVK-------PVLQKLGQDEDMDVKYF 590
Query: 598 SAQSL 602
+ +++
Sbjct: 591 AQEAI 595
Score = 77.0 bits (188), Expect = 8e-14
Identities = 83/418 (19%), Positives = 170/418 (39%), Gaps = 17/418 (4%)
Query: 29 RVEAMKKLDTIALALGVQRTRDELIPFLTEVAQDDEDEVFAVLAEQLGNFVPFVGGRKYA 88
R A KL A L + + E++P T +A D++D V + E + +
Sbjct: 194 RRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLE 253
Query: 89 TLLLPALEILASTEETLVREKAVDSLNMVAEQLTEEQLLHDFVPLIENLATNEWFSSKVS 148
TL++P L A + VR D + + + + + L+D +P +NL + + +
Sbjct: 254 TLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAA 313
Query: 149 ACGLFKAVFVRI----QDDKFRKDLLSLFLQLIQDDTPMVRRAAGRNLPTLVDQLTEHPE 204
A K + + ++ +L +L+ D V+ A L +++ L+
Sbjct: 314 AAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSA----LASVIMGLSTI-- 367
Query: 205 LSTDDEWDYISSMFQRLVNDSQDSVKFLAVDVLISILKFFNKKKDFTHTKDLLQSSIQLI 264
L ++ +++ +F + D V+ + L + + ++ ++ LL + ++L
Sbjct: 368 LGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQ---LSQSLLPAIVELA 424
Query: 265 GDEAWRVRYMAADRFEELASQFVSNPQYVSELLEPF-LALCQDNESDVRKAIAKQIPGYA 323
D WRVR + LA Q ++ E L +A D+ +R+A +
Sbjct: 425 EDAKWRVRLAIIEYMPLLAGQL--GVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLV 482
Query: 324 KLLNDPSVILNRIIPAAQNLSIDETECVRASLALEITNLAPLLPKQDSMDSLVPILLHML 383
+ N I+P ++ D R + I L+ ++ + ++PI+L M
Sbjct: 483 QKFGTEWA-QNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKMA 541
Query: 384 KDEFPDVRLNIIAKLKIVNESVGIEFLSENLLPAITELAKDPNWRVRLAIIEYIPLLA 441
D+ +VR N+ L+ + + L + P + +L +D + V+ E I +LA
Sbjct: 542 GDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLA 599
>Hs21361399 [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 589
Score = 452 bits (1162), Expect = e-127
Identities = 261/602 (43%), Positives = 376/602 (62%), Gaps = 26/602 (4%)
Query: 5 SDSKVNLYPLALLMDELKHDDISNRVEAMKKLDTIALALGVQRTRDELIPFLTEVAQDDE 64
+D +LYP+A+L+DEL+++D+ R+ ++KKL TIALALGV+RTR EL+PFLT+ D E
Sbjct: 4 ADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYD-E 62
Query: 65 DEVFAVLAEQLGNFVPFVGGRKYATLLLPALEILASTEETLVREKAVDSLNMVAEQLTEE 124
DEV LAEQLG F VGG +Y LLP LE LA+ EET+VR+KAV+SL ++ + +
Sbjct: 63 DEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPS 122
Query: 125 QLLHDFVPLIENLATNEWFSSKVSACGLFKAVFVRIQDDKFRKDLLSLFLQLIQDDTPMV 184
L FVPL++ LA +WF+S+ SACGLF + R+ + +L F L DDTPMV
Sbjct: 123 DLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSS-AVKAELRQYFRNLCSDDTPMV 181
Query: 185 RRAAGRNLPTLVDQLTEHPELSTDDEWDYISSMFQRLVNDSQDSVKFLAVDVLISILKFF 244
RRAA L L D+ I MF L +D QDSV+ LAV+ ++I +
Sbjct: 182 RRAAASKLGEFAKVL------ELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL 235
Query: 245 NKKKDFTHTKDLLQSSIQLIGDEAWRVRYMAADRFEELASQFVSNPQYV-SELLEPFLAL 303
++ L+ + + D++WRVRYM AD+F EL Q P+ ++L+ F L
Sbjct: 236 PQEDLEALVMPTLRQAAE---DKSWRVRYMVADKFTEL--QKAVGPEITKTDLVPAFQNL 290
Query: 304 CQDNESDVRKAIAKQIPGYAKLLNDP---SVILNRIIPAAQNLSIDETECVRASLALEIT 360
+D E++VR A + ++ + + L+ +VI+++I+P + L D + V+++LA I
Sbjct: 291 MKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIM 350
Query: 361 NLAPLLPKQDSMDSLVPILLHMLKDEFPDVRLNIIAKLKIVNESVGIEFLSENLLPAITE 420
L+P+L K ++++ L+P+ L LKDE P+VRLNII+ L VNE +GI LS++LLPAI E
Sbjct: 351 GLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVE 410
Query: 421 LAKDPNWRVRLAIIEYIPLLAEQLGMEFFDSKLSDLCLSWLWDGVYSIRSAAITNLSKLT 480
LA+D WRVRLAIIEY+PLLA QLG+EFFD KL+ LC++WL D VY+IR AA +NL KL
Sbjct: 411 LAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLV 470
Query: 481 EIFGSDWAQEEIISRLLKSDTQLLENFNYRITLLFALTGLVPVVSTDVVVEKILPFVNHL 540
E FG +WA II ++L N+ +R+T LF + L V D+ + +LP V +
Sbjct: 471 EKFGKEWAHATIIPKVLAMSGD--PNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRM 528
Query: 541 STDNVPNIRFNVAKFYAVIVEALTKNTNKNHIELINNTIIPTLEKLCQDPDVDVRFFSAQ 600
+ D V N+RFNVAK I L +T ++ ++ P LEKL QD DVDV++F+ +
Sbjct: 529 AGDPVANVRFNVAKSLQKIGPILDNSTLQSEVK-------PILEKLTQDQDVDVKYFAQE 581
Query: 601 SL 602
+L
Sbjct: 582 AL 583
>HsM7657475 [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 589
Score = 449 bits (1156), Expect = e-126
Identities = 260/602 (43%), Positives = 375/602 (62%), Gaps = 26/602 (4%)
Query: 5 SDSKVNLYPLALLMDELKHDDISNRVEAMKKLDTIALALGVQRTRDELIPFLTEVAQDDE 64
+D +LYP+A+L+DEL+++D+ R+ ++KKL TIALALGV+RTR EL+PFLT+ D E
Sbjct: 4 ADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYD-E 62
Query: 65 DEVFAVLAEQLGNFVPFVGGRKYATLLLPALEILASTEETLVREKAVDSLNMVAEQLTEE 124
DEV LAEQLG F VGG +Y LLP LE LA+ EET+VR+KAV+SL ++ + +
Sbjct: 63 DEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPS 122
Query: 125 QLLHDFVPLIENLATNEWFSSKVSACGLFKAVFVRIQDDKFRKDLLSLFLQLIQDDTPMV 184
L FVPL++ LA +WF+S+ SACGLF + R+ + +L F L DDTPMV
Sbjct: 123 DLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSS-AVKAELRQYFRNLCSDDTPMV 181
Query: 185 RRAAGRNLPTLVDQLTEHPELSTDDEWDYISSMFQRLVNDSQDSVKFLAVDVLISILKFF 244
RRAA L L D+ I MF L +D QDSV+ LAV+ ++I +
Sbjct: 182 RRAAASKLGEFAKVL------ELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL 235
Query: 245 NKKKDFTHTKDLLQSSIQLIGDEAWRVRYMAADRFEELASQFVSNPQYV-SELLEPFLAL 303
++ L+ + + D++W VRYM AD+F EL Q P+ ++L+ F L
Sbjct: 236 PQEDLEALVMPTLRQAAE---DKSWAVRYMVADKFTEL--QKAVGPEITKTDLVPAFQNL 290
Query: 304 CQDNESDVRKAIAKQIPGYAKLLNDP---SVILNRIIPAAQNLSIDETECVRASLALEIT 360
+D E++VR A + ++ + + L+ +VI+++I+P + L D + V+++LA I
Sbjct: 291 MKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIM 350
Query: 361 NLAPLLPKQDSMDSLVPILLHMLKDEFPDVRLNIIAKLKIVNESVGIEFLSENLLPAITE 420
L+P+L K ++++ L+P+ L LKDE P+VRLNII+ L VNE +GI LS++LLPAI E
Sbjct: 351 GLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVE 410
Query: 421 LAKDPNWRVRLAIIEYIPLLAEQLGMEFFDSKLSDLCLSWLWDGVYSIRSAAITNLSKLT 480
LA+D WRVRLAIIEY+PLLA QLG+EFFD KL+ LC++WL D VY+IR AA +NL KL
Sbjct: 411 LAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLV 470
Query: 481 EIFGSDWAQEEIISRLLKSDTQLLENFNYRITLLFALTGLVPVVSTDVVVEKILPFVNHL 540
E FG +WA II ++L N+ +R+T LF + L V D+ + +LP V +
Sbjct: 471 EKFGKEWAHATIIPKVLAMSGD--PNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRM 528
Query: 541 STDNVPNIRFNVAKFYAVIVEALTKNTNKNHIELINNTIIPTLEKLCQDPDVDVRFFSAQ 600
+ D V N+RFNVAK I L +T ++ ++ P LEKL QD DVDV++F+ +
Sbjct: 529 AGDPVANVRFNVAKSLQKIGPILDNSTLQSEVK-------PILEKLTQDQDVDVKYFAQE 581
Query: 601 SL 602
+L
Sbjct: 582 AL 583
>At1g13320 [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 624
Score = 442 bits (1138), Expect = e-124
Identities = 265/630 (42%), Positives = 381/630 (60%), Gaps = 59/630 (9%)
Query: 11 LYPLALLMDELKHDDISNRVEAMKKLDTIALALGVQRTRDELIPFLTEVAQDDEDEVFAV 70
LYP+A+L+DELK+DDI R+ ++K+L IA ALG +RTR ELIPFL+E DD+DEV
Sbjct: 8 LYPIAVLIDELKNDDIQRRLNSIKRLSIIARALGEERTRKELIPFLSE-NNDDDDEVLLA 66
Query: 71 LAEQLGNFVPFVGGRKYATLLLPALEILASTEETLVREKAVDSLNMVAEQLTEEQLLHDF 130
+AE+LG F+ +VGG +YA +LLP LE L++ EET VREKAVDSL + Q+ E L+ F
Sbjct: 67 MAEELGGFILYVGGVEYAYVLLPPLETLSTVEETCVREKAVDSLCRIGAQMRESDLVEHF 126
Query: 131 VPLIE---NLATNEWFSS------------------------------KVSACGLFKAVF 157
PL + + + F+S +VSACG+F +
Sbjct: 127 TPLAKVFWEIGRLKLFTSILVDLREHRSGFSALLGCGCVCDHTYLGIARVSACGIFHIAY 186
Query: 158 VRIQDDKFRKDLLSLFLQLIQDDTPMVRRAAGRNLPTLVDQLTEHPELSTDDEWDYISSM 217
D + +L S++ QL QDD PMVRRAA NL + E L TD I SM
Sbjct: 187 PSAPD-VLKTELRSIYGQLCQDDMPMVRRAAATNLGKFAATI-ESAHLKTD-----IMSM 239
Query: 218 FQRLVNDSQDSVKFLAVDVLISILKFFNKKKDFTHTKDLLQSSIQLIGDEAWRVRYMAAD 277
F+ L D QDSV+ LAV+ ++ K + H +L + D++WRVRYM A+
Sbjct: 240 FEDLTQDDQDSVRLLAVEGCAALGKLLEPQDCVAH---ILPVIVNFSQDKSWRVRYMVAN 296
Query: 278 RFEELASQFVSNPQYVSELLEPFLALCQDNESDVRKAIAKQIPGYAKLLNDPSVILNRII 337
+ EL P ++L+ + L DNE++VR A A ++ + ++LN P + + I+
Sbjct: 297 QLYELCEAVGPEPTR-TDLVPAYARLLCDNEAEVRIAAAGKVTKFCRILN-PELAIQHIL 354
Query: 338 PAAQNLSIDETECVRASLALEITNLAPLLPKQDSMDSLVPILLHMLKDEFPDVRLNIIAK 397
P + LS D ++ VR++LA I +AP+L K +++ L+PI L +LKDEFPDVRLNII+K
Sbjct: 355 PCVKELSSDSSQHVRSALASVIMGMAPVLGKDATIEHLLPIFLSLLKDEFPDVRLNIISK 414
Query: 398 LKIVNESVGIEFLSENLLPAITELAKDPNWRVRLAIIEYIPLLAEQLGMEFFDSKLSDLC 457
L VN+ +GI+ LS++LLPAI ELA+D +WRVRLAIIEYIPLLA QLG+ FFD KL LC
Sbjct: 415 LDQVNQVIGIDLLSQSLLPAIVELAEDRHWRVRLAIIEYIPLLASQLGVGFFDEKLGALC 474
Query: 458 LSWLWDGVYSIRSAAITNLSKLTEIFGSDWAQEEIISRLLKSDTQLLENFNYRITLLFAL 517
+ WL D V+SIR AA NL +L E FG +WA + I+ ++L+ ++ YR+T+L A+
Sbjct: 475 MQWLQDKVHSIREAAANNLKRLAEEFGPEWAMQHIVPQVLEMINN--PHYLYRMTILRAV 532
Query: 518 TGLVPVVSTDVVVEKILPFVNHLST----DNVPNIRFNVAKFYAVIVEALTKNTNKNHIE 573
+ L PV+ +++ K+LP + +T VPNI+FNVAK ++ + +
Sbjct: 533 SLLAPVMGSEITCSKLLPALTKRTTLSSSFRVPNIKFNVAKMMQSLIPIVDQ-------A 585
Query: 574 LINNTIIPTLEKLCQDPDVDVRFFSAQSLE 603
++ N I P L +L +DPDVDVR+F+ Q+L+
Sbjct: 586 VVENMIRPCLVELSEDPDVDVRYFANQALQ 615
>7297392 [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 591
Score = 442 bits (1138), Expect = e-124
Identities = 265/604 (43%), Positives = 375/604 (61%), Gaps = 28/604 (4%)
Query: 5 SDSKVN--LYPLALLMDELKHDDISNRVEAMKKLDTIALALGVQRTRDELIPFLTEVAQD 62
SD V+ LYP+A+L+DELK++D+ R+ ++KKL TIALALG +RTR ELIPFLTE D
Sbjct: 4 SDKSVDDSLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGEERTRSELIPFLTETIYD 63
Query: 63 DEDEVFAVLAEQLGNFVPFVGGRKYATLLLPALEILASTEETLVREKAVDSLNMVAEQLT 122
EDEV LA+QLGNF VGG ++A L+P LE LA+ EET+VR+KAV+SL VA + +
Sbjct: 64 -EDEVLLALADQLGNFTSLVGGPEFAMYLIPPLESLATVEETVVRDKAVESLRTVAAEHS 122
Query: 123 EEQLLHDFVPLIENLATNEWFSSKVSACGLFKAVFVRIQDDKFRKDLLSLFLQLIQDDTP 182
+ L VP ++ L + +WF+S+ SACGLF + R+ + +L + F +L QD+TP
Sbjct: 123 AQDLEIHVVPTLQRLVSGDWFTSRTSACGLFSVCYPRVTQP-VKAELRANFRKLCQDETP 181
Query: 183 MVRRAAGRNLPTLVDQLTEHPELSTDDEWDYISSMFQRLVNDSQDSVKFLAVDVLISILK 242
MVRRAA L ++ E L +D + F +L D QDSV+ LAV+ +SI +
Sbjct: 182 MVRRAAANKLGEFA-KVVETEYLKSD-----LIPNFVQLAQDDQDSVRLLAVEACVSIAQ 235
Query: 243 FFNKKKDFTHTKDLLQSSIQLIGDEAWRVRYMAADRFEELASQFVSNPQYVS-ELLEPFL 301
+ D H +L + Q D +WRVRYM A++F +L Q P+ +L+ F
Sbjct: 236 LL-PQDDVEHL--VLPTLRQCASDSSWRVRYMVAEKFVDL--QKAVGPEITRVDLVPAFQ 290
Query: 302 ALCQDNESDVRKAIAKQIPGYAKLL---NDPSVILNRIIPAAQNLSIDETECVRASLALE 358
L +D E++VR A+A ++ + L N +IL+ I+P ++L D V+++LA
Sbjct: 291 YLLKDAEAEVRAAVATKVKDFCANLDKVNQVQIILSSILPYVRDLVSDPNPHVKSALASV 350
Query: 359 ITNLAPLLPKQDSMDSLVPILLHMLKDEFPDVRLNIIAKLKIVNESVGIEFLSENLLPAI 418
I L+P+L +++ L+P+ L LKDE P+VRLNII+ L VN+ +GI+ LS++LLPAI
Sbjct: 351 IMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIGIQQLSQSLLPAI 410
Query: 419 TELAKDPNWRVRLAIIEYIPLLAEQLGMEFFDSKLSDLCLSWLWDGVYSIRSAAITNLSK 478
ELA+D WRVRLAIIEY+P LA QLG EFFD KL LC+ WL D VY+IR AA N+ K
Sbjct: 411 VELAEDSKWRVRLAIIEYMPALAGQLGQEFFDQKLRGLCMGWLNDHVYAIREAATLNMKK 470
Query: 479 LTEIFGSDWAQEEIISRLLKSDTQLLENFNYRITLLFALTGLVPVVSTDVVVEKILPFVN 538
L E FG+ WA++ II +L +N+ +R+T LF L L V TD+ + +LP V
Sbjct: 471 LVEQFGAPWAEQAIIPMILVMSRN--KNYLHRMTCLFCLNVLAEVCGTDITTKLLLPTVL 528
Query: 539 HLSTDNVPNIRFNVAKFYAVIVEALTKNTNKNHIELINNTIIPTLEKLCQDPDVDVRFFS 598
L+ D V N+RFNVAK L K + +I+ + PTL+KL D DVDV+ F+
Sbjct: 529 LLAADPVANVRFNVAK-------TLQKISPFLEASVIDAQVKPTLDKLNTDTDVDVKHFA 581
Query: 599 AQSL 602
AQ++
Sbjct: 582 AQAI 585
>CE01957 [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 664
Score = 422 bits (1086), Expect = e-118
Identities = 249/597 (41%), Positives = 368/597 (60%), Gaps = 30/597 (5%)
Query: 11 LYPLALLMDELKHDDISNRVEAMKKLDTIALALGVQRTRDELIPFLTEVAQDDEDEVFAV 70
LYP+A+L+DEL+++D++ R+ +++KL TIALALGV+RTR+ELI FLT+ D EDEV V
Sbjct: 86 LYPIAVLIDELRNEDVTLRLNSIRKLSTIALALGVERTRNELIQFLTDTIYD-EDEVLLV 144
Query: 71 LAEQLGNFVPFVGGRKYATLLLPALEILASTEETLVREKAVDSLNMVAEQLTEEQLLHDF 130
LAEQLGNF P VGG + LL LE LA+ EET+VR+KAV+SL +A++ + L F
Sbjct: 145 LAEQLGNFTPLVGGPDHVHCLLLPLENLATVEETVVRDKAVESLRKIADKHSSASLEEHF 204
Query: 131 VPLIENLATNEWFSSKVSACGLFKAVFVRIQDDKFRKDLLSLFLQLIQDDTPMVRRAAGR 190
VP++ LAT +WF+S+ SACGLF V+ R+ + +L S+F L +DDTPMVRRAA
Sbjct: 205 VPMLRRLATGDWFTSRTSACGLFSVVYPRVSP-AIKSELKSMFRTLCRDDTPMVRRAAAA 263
Query: 191 NLPTLVDQLTEHPELSTDDEWDYISSMFQRLVNDSQDSVKFLAVDVLISILKFFNKKKDF 250
L + + + + S L D QDSV+ L V+ I+ F D
Sbjct: 264 KLGEFAKVFEKTAVI------EGLHSSLTDLHVDEQDSVRLLTVESAIA----FGTLLDK 313
Query: 251 THTKDLLQSS-IQLIGDEAWRVRYMAADRFEELASQFVSNPQYVSELLEPFLALCQDNES 309
+ K L++ I+L D++WRVRYM A++ E+ + + + L+ + L +D E
Sbjct: 314 ANKKKLIEPILIELFDDKSWRVRYMVAEKLIEIQN-VLGEDMDTTHLVNMYTNLLKDPEG 372
Query: 310 DVRKAIAKQIPGYAKLLNDP---SVILNRIIPAAQNLSIDETECVRASLALEITNLAPLL 366
+VR A +++ +A L + ++I N ++ A+ L D + V++ LA I LAPL+
Sbjct: 373 EVRCAATQRLQEFALNLPEDKRQNIICNSLLNVAKELVTDGNQLVKSELAGVIMGLAPLI 432
Query: 367 PKQDSMDSLVPILLHMLKDEFPDVRLNIIAKLKIVNESVGIEFLSENLLPAITELAKDPN 426
K+ ++ L+PI + +L D+ P+VRLNII+ L VNE +G LS +LLPAI LA+D
Sbjct: 433 GKEQTVSELLPIYMQLLNDQTPEVRLNIISSLDKVNEVIGAAQLSTSLLPAIVGLAEDGK 492
Query: 427 WRVRLAIIEYIPLLAEQLGMEFFDSKLSDLCLSWLWDGVYSIRSAAITNLSKLTEIFGSD 486
WRVRLAI++++PLLA QLG EFFD KL LCL+WL D V+SIR A+ + +LT+ FG
Sbjct: 493 WRVRLAIVQFMPLLASQLGQEFFDEKLLPLCLNWLTDHVFSIREASTLIMKELTQKFGGQ 552
Query: 487 WAQEEIISRL--LKSDTQLLENFNYRITLLFALTGLVPVVSTDVVVEKILPFVNHLSTDN 544
WA I+ ++ L+ DT N+ R+T LF L L ++ + ++++I+P V L D+
Sbjct: 553 WASTNIVPKMQKLQKDT----NYLQRMTCLFCLNTLSEAMTQEQILKEIMPIVKDLVEDD 608
Query: 545 VPNIRFNVAKFYAVIVEALTKNTNKNHIELINNTIIPTLEKLCQDPDVDVRFFSAQS 601
VPN+RFN AK I + LT +T + + + P LEKL +D D DVR+FS ++
Sbjct: 609 VPNVRFNAAKSLKRIGKNLTPST-------LTSEVKPLLEKLGKDSDFDVRYFSEEA 658
>Hs4826934 [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 933
Score = 56.6 bits (135), Expect = 1e-07
Identities = 82/329 (24%), Positives = 136/329 (40%), Gaps = 44/329 (13%)
Query: 296 LLEPFLAL-----CQDNESDVRKAIAKQIPGYAKLLNDPSVILNRIIPAAQNLSIDETEC 350
LL+ +L++ Q ++++ K A +PG A L + R + L+ D
Sbjct: 604 LLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLR--ETYETLASDMQWK 661
Query: 351 VRASLALEITNLAPLLPKQDSMDSLVPILLHMLKDEFPDVRLNIIAKLKIVNESVGIEFL 410
VR +LA I LA +L Q + LVPI LKD +VR+ ++ L + + I+
Sbjct: 662 VRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVLKHLHDFLKLLHIDKR 720
Query: 411 SENLLPAITELAKD--PNWRVRLAIIEYIPLLAEQLGMEFFDSKLSDLCLSWLWDGVYSI 468
E L L D NWR R + E + LL E L + L+ D V S+
Sbjct: 721 REYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSV 780
Query: 469 RSAAITNLSKLTE--------IFGSDWAQEEIISRLLKSDTQLLENF------NYRITLL 514
R + +S++ + FG D E L+ENF + R +
Sbjct: 781 RWISYKLVSEMVKKLHAATPPTFGVDLINE------------LVENFGRCPKWSGRQAFV 828
Query: 515 FALTGLV--PVVSTDVVVEKILPFVNHLSTDNVPNIRFNVAKF--YAVIVEALTKNTNKN 570
F ++ + D ++P + L+ D VPN+R +AK ++ + +
Sbjct: 829 FVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASC 888
Query: 571 HIELINNTIIPTLEKLCQDPDVDVRFFSA 599
H E + TI+ L D D DV++F++
Sbjct: 889 HQEAVEQTIM----ALQMDRDSDVKYFAS 913
>CE20811 [T] KOG0211 Protein phosphatase 2A regulatory subunit A and related
proteins
Length = 849
Score = 53.9 bits (128), Expect = 7e-07
Identities = 96/496 (19%), Positives = 198/496 (39%), Gaps = 40/496 (8%)
Query: 111 VDSLNMVAEQLTEEQLLHDFVPLIENLATN-EWFSSKVSACGLFKAVFVRIQDDKFRKDL 169
++++ VA++L+ + VP+I+ A + ++ A + + + + ++ RK+L
Sbjct: 224 LETIVEVADKLSLSSIKLYVVPVIQTQAEPVQRVQRRIIATKIIHKLALFLPPNEIRKEL 283
Query: 170 LSLFLQLIQDDTPMVRRAAGRNLPTLVDQLTEHPELSTDDEWDYISSMFQRLVNDSQDSV 229
+ L +D VR A + L + + L ++ D + + L+ND + +V
Sbjct: 284 CPIVTTLCKDANSNVRVAVAQRLFVIANALK-----NSHDVVSCLLPSYVHLLNDEEMNV 338
Query: 230 KFLAVDVLISILKFFN----KKKDFTHTKDLLQSSIQ-------LIGDEAWRVRYMAADR 278
+ A++ L F K F+ K L + +++ +I + + + +
Sbjct: 339 REAAMNSLTDAFSLFTRDARKHTLFSVIKKLTEEALEKKNEGLAVISNNFGKWSWELNEL 398
Query: 279 FEELASQFVSNPQYVSELLEPFLALCQDNESDVRKAIAKQIP-GYAKLLNDPSVILNRII 337
++L +V N ++++ LC+ + ++R + K Y +L ++R++
Sbjct: 399 LDQLDKSWVLNTY--CKMVQISDELCEGPQKNIRNVLKKTCCFNYPCMLTMFKKHVDRLL 456
Query: 338 PAAQNLSIDETECVRASLALEITNLAPLLP-KQDSMDSLVPILLHMLKDEFPDVRLNIIA 396
P + D E VR S+A + + P K D + + +L D + N+
Sbjct: 457 PFLEMFCTDHDEEVRVSIASSYHEVLTMFPDKPDLIPPFIELLHGGSSDVIAKISHNLSK 516
Query: 397 KLKIVNESVG-------IEFLSENLLPAITELAKDPNWRVRLAIIEYIPLLAEQLGMEFF 449
L I+ E+V ++ + LL L +WR A ++ + L + E
Sbjct: 517 ILPILYENVKENPGRTTVQQVDRLLLGCNQILRTSSSWRSHEAFLKSLKTLTNCIDEEV- 575
Query: 450 DSKLSDLCLSWLWDGVYSIRS------AAITNLSKLTEIFGSDWAQEEIISRLLKSDTQL 503
+ D + L V ++R+ A T L L I +D E I + +
Sbjct: 576 ---IIDTFVPLLRKEVLNVRAIPCRIAACETLLILLKSISKADTRTE--IMQFFNEELST 630
Query: 504 LENFNYRITLLFALTGLVPVVSTDVVVEKILPFVNHLSTDNVPNIRFNVAKFYAVIVEAL 563
RIT + ++ V S + ++ L L++D V NIR KF I L
Sbjct: 631 HSCCYRRITYIDVAELVLSVFSKRIFIQHFLDDTLRLTSDPVSNIRIRAIKFLPKIKSKL 690
Query: 564 TKNTNKNHIELINNTI 579
++ + I N++
Sbjct: 691 ILPEDEEVLLKIENSV 706
>Hs14728229 [T] KOG1240 Protein kinase containing WD40 repeats
Length = 1358
Score = 52.0 bits (123), Expect = 3e-06
Identities = 29/111 (26%), Positives = 58/111 (52%), Gaps = 1/111 (0%)
Query: 492 IISRLLKSDTQLLENFNYRITLLFALTGLVPVVSTDVVVEKILPFVNHLSTDNVPNIRFN 551
I+ ++ S Q L+ + ++ L + L P +S ++++++I P++ H S D+VP +R
Sbjct: 377 ILVSVITSCLQTLKYCDSKLAALELILHLAPRLSVEILLDRITPYLLHFSNDSVPRVRAE 436
Query: 552 VAKFYAVIVEALTKNTNKNHIELINNTIIPTLEKLCQDPDVDVRFFSAQSL 602
+ ++ AL K +N I + I+P + L QD VR A+++
Sbjct: 437 ALRTLTKVL-ALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRLAYAENI 486
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.137 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,843,186
Number of Sequences: 60738
Number of extensions: 1386267
Number of successful extensions: 4914
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 4566
Number of HSP's gapped (non-prelim): 46
length of query: 610
length of database: 30,389,216
effective HSP length: 112
effective length of query: 498
effective length of database: 23,586,560
effective search space: 11746106880
effective search space used: 11746106880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)