ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2036 good L KOG1921 Replication, recombination and repair Endonuclease III
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2036 731004 729832 -391
(391 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL043c [L] KOG1921 Endonuclease III 312 6e-85
YAL015c [L] KOG1921 Endonuclease III 257 2e-68
SPAC30D11.07 [L] KOG1921 Endonuclease III 182 6e-46
At2g31450 [L] KOG1921 Endonuclease III 172 1e-42
Hs4505471 [L] KOG1921 Endonuclease III 166 7e-41
7298737 [L] KOG1921 Endonuclease III 152 8e-37
CE03559 [L] KOG1921 Endonuclease III 151 1e-36
At1g05900_2 [L] KOG1921 Endonuclease III 142 1e-33
ECU08g0880 [L] KOG1921 Endonuclease III 120 3e-27
>YOL043c [L] KOG1921 Endonuclease III
Length = 380
Score = 312 bits (799), Expect = 6e-85
Identities = 162/327 (49%), Positives = 211/327 (63%), Gaps = 10/327 (3%)
Query: 5 KRPRVNVEVE-LETVSKYFKKEPEDQVVVKVEG-NHDIKT--DPEIEAIKTMGTDEYFKY 60
KR + V++E +E SKYFKK +VK N D++ I+ IK + EYF++
Sbjct: 9 KRKHIPVDIEEVEVRSKYFKKNERTVELVKENKINKDLQNYGGVNIDWIKALKPIEYFEW 68
Query: 61 VQKFTNDDIS-----LNRKLQIEDN-PNMPSNFVSIYSKVRFMRSMIKTPVDNVGCAMLP 114
++ T DD + ++ I D+ +P +F+ IY++VR MRS +KTPVD +GC+M+P
Sbjct: 69 IESRTCDDPRTWGRPITKEEMINDSGAKVPESFLPIYNRVRLMRSKVKTPVDAMGCSMIP 128
Query: 115 ITINGVFGISKSNMQPKNYRXXXXXXXXXXXXTKDEVNAKAMHNIMEYCMEELGDPEGIT 174
+ ++ GI + PKN+R T+DE A+A NI EYC+ L EGIT
Sbjct: 129 VLVSNKCGIPSEKVDPKNFRLQFLIGTMLSAQTRDERMAQAALNITEYCLNTLKIAEGIT 188
Query: 175 LGSLLKIEEKILDKEIYSVGFHTRKASYIKKAAVMLRDQFDGDVPTTIEGFMSLPGVGPK 234
L LLKI+E +L I V F+TRKA++IK+ A +L D FD D+P IEG +SLPGVGPK
Sbjct: 189 LDGLLKIDEPVLANLIRCVSFYTRKANFIKRTAQLLVDNFDSDIPYDIEGILSLPGVGPK 248
Query: 235 MGYLALQKSWAKIDGIGVDVHVDRLAKMWKWVDPKVCKTPEHTRKQLESWLPRSLWYEIN 294
MGYL LQK W I GI VDVHV RL KMW WVDP CKT EHTRK+L+ WLP SLWYEIN
Sbjct: 249 MGYLTLQKGWGLIAGICVDVHVHRLCKMWNWVDPIKCKTAEHTRKELQVWLPHSLWYEIN 308
Query: 295 PVLVGFGQVLCMPRSKRCELCLVNDIC 321
VLVGFGQ++CM R KRC+LCL ND+C
Sbjct: 309 TVLVGFGQLICMARGKRCDLCLANDVC 335
>YAL015c [L] KOG1921 Endonuclease III
Length = 399
Score = 257 bits (656), Expect = 2e-68
Identities = 136/313 (43%), Positives = 192/313 (60%), Gaps = 17/313 (5%)
Query: 5 KRPRVNVEVELETVSKYFKKEPEDQVVVKVEGNHDIKTDP-EIEAIKTMGTDEYFKYVQK 63
KRP V E E+ + PE + +K E ++ P +I+ +K++ +YF+++
Sbjct: 15 KRPLVKTETGPES-----ELLPEKRTKIKQE---EVVPQPVDIDWVKSLPNKQYFEWIV- 65
Query: 64 FTNDDISLNRKLQIEDN-------PNMPSNFVSIYSKVRFMRSMIKTPVDNVGCAMLPIT 116
N ++ ++ + +P F Y+++R +RS I PVD +G + +P+T
Sbjct: 66 VRNGNVPNRWATPLDPSILVTPASTKVPYKFQETYARMRVLRSKILAPVDIIGGSSIPVT 125
Query: 117 INGVFGISKSNMQPKNYRXXXXXXXXXXXXTKDEVNAKAMHNIMEYCMEELGDPEGITLG 176
+ GISK + P++YR TKDEV A AM NIM YC++EL EG+TL
Sbjct: 126 VASKCGISKEQISPRDYRLQVLLGVMLSSQTKDEVTAMAMLNIMRYCIDELHSEEGMTLE 185
Query: 177 SLLKIEEKILDKEIYSVGFHTRKASYIKKAAVMLRDQFDGDVPTTIEGFMSLPGVGPKMG 236
++L+I E LD+ I+SVGFHTRKA YI +L+DQF DVP TI + LPGVGPKM
Sbjct: 186 AVLQINETKLDELIHSVGFHTRKAKYILSTCKILQDQFSSDVPATINELLGLPGVGPKMA 245
Query: 237 YLALQKSWAKIDGIGVDVHVDRLAKMWKWVDPKVCKTPEHTRKQLESWLPRSLWYEINPV 296
YL LQK+W KI+GI VDVHVDRL K+WKWVD + CKTP+ TR QL++WLP+ LW EIN +
Sbjct: 246 YLTLQKAWGKIEGICVDVHVDRLTKLWKWVDAQKCKTPDQTRTQLQNWLPKGLWTEINGL 305
Query: 297 LVGFGQVLCMPRS 309
LVGFGQ++ R+
Sbjct: 306 LVGFGQIITKSRN 318
>SPAC30D11.07 [L] KOG1921 Endonuclease III
Length = 355
Score = 182 bits (463), Expect = 6e-46
Identities = 96/247 (38%), Positives = 135/247 (53%), Gaps = 22/247 (8%)
Query: 78 EDNPNMPSNFVSIYSKVRFMRSMIKTPVDNVGCAMLPITINGVFGISKSNMQPKNYRXXX 137
+D P N+ +Y ++ M++ + PVD GC L PK +R
Sbjct: 3 KDYGTPPENWREVYDEICKMKAKVVAPVDVQGCHTLG-----------ERNDPKKFRFQT 51
Query: 138 XXXXXXXXXTKDEVNAKAMHNIMEYCMEELGDPEGITLGSLLKIEEKILDKEIYSVGFHT 197
TKD V M N+ E G+ L + I+E L+K I VGFH
Sbjct: 52 LVALMLSSQTKDIVLGPTMRNLKEKLAG------GLCLEDIQNIDEVSLNKLIEKVGFHN 105
Query: 198 RKASYIKKAAVMLRDQFDGDVPTTIEGFMSLPGVGPKMGYLALQKSWAKIDGIGVDVHVD 257
RK Y+K+ A +L ++F GD+P T+E M+LPGVGPKMGYL + +W K GIGVDVHV
Sbjct: 106 RKTIYLKQMARILSEKFQGDIPDTVEDLMTLPGVGPKMGYLCMSIAWNKTVGIGVDVHVH 165
Query: 258 RLAKMWKWVDPKVCKTPEHTRKQLESWLPRSLWYEINPVLVGFGQVLCMPRSKRCELCLV 317
R+ + W + KT E TR L+SWLP+ LW+E+N LVGFGQ +C+PR +RC++C +
Sbjct: 166 RICNLLHWCN---TKTEEQTRAALQSWLPKELWFELNHTLVGFGQTICLPRGRRCDMCTL 222
Query: 318 ND--ICP 322
+ +CP
Sbjct: 223 SSKGLCP 229
>At2g31450 [L] KOG1921 Endonuclease III
Length = 281
Score = 172 bits (435), Expect = 1e-42
Identities = 100/270 (37%), Positives = 141/270 (52%), Gaps = 32/270 (11%)
Query: 66 NDDISLNRKLQIED--------NPNMP-SNFVSIYSKVRFMRSMIKTPVDNVGCAMLPIT 116
ND + L LQI NP P N+V + +R MRS PVD++GC
Sbjct: 9 NDRVGLVFTLQISSHTVTCYVYNPGYPPENWVEVLEGIRQMRSSEDAPVDSMGCDK---- 64
Query: 117 INGVFGISKSNMQPKNYRXXXXXXXXXXXXTKDEVNAKAMHNIMEYCMEELGDPEGITLG 176
+ S + P R TKD+VN A+H + + L PE +
Sbjct: 65 -------AGSFLPPTERRFAVLLGALLSSQTKDQVNNAAIHRLHQ---NGLLTPEAVD-- 112
Query: 177 SLLKIEEKILDKEIYSVGFHTRKASYIKKAAVMLRDQFDGDVPTTIEGFMSLPGVGPKMG 236
K +E + + IY VGF+TRKA+Y+KK A + ++DGD+P++++ +SLPG+GPKM
Sbjct: 113 ---KADESTIKELIYPVGFYTRKATYMKKIARICLVKYDGDIPSSLDDLLSLPGIGPKMA 169
Query: 237 YLALQKSWAKIDGIGVDVHVDRLAKMWKWVDPKVCK----TPEHTRKQLESWLPRSLWYE 292
+L L +W + GI VD HV R+ WV K +PE TR L+ WLP+ W
Sbjct: 170 HLILHIAWNDVQGICVDTHVHRICNRLGWVSRPGTKQKTTSPEETRVALQQWLPKEEWVA 229
Query: 293 INPVLVGFGQVLCMPRSKRCELCLVNDICP 322
INP+LVGFGQ++C P RCE C V+ +CP
Sbjct: 230 INPLLVGFGQMICTPIRPRCEACSVSKLCP 259
>Hs4505471 [L] KOG1921 Endonuclease III
Length = 312
Score = 166 bits (419), Expect = 7e-41
Identities = 89/239 (37%), Positives = 125/239 (52%), Gaps = 20/239 (8%)
Query: 84 PSNFVSIYSKVRFMRSMIKTPVDNVGCAMLPITINGVFGISKSNMQPKNYRXXXXXXXXX 143
P ++ +R MR+ PVD++G S+ PK R
Sbjct: 89 PQDWQQQLVNIRAMRNKKDAPVDHLGTEHC----------YDSSAPPKVRRYQVLLSLML 138
Query: 144 XXXTKDEVNAKAMHNIMEYCMEELGDPEGITLGSLLKIEEKILDKEIYSVGFHTRKASYI 203
TKD+V A AM + G+T+ S+L+ ++ L K IY VGF K YI
Sbjct: 139 SSQTKDQVTAGAMQRLRA---------RGLTVDSILQTDDATLGKLIYPVGFWRSKVKYI 189
Query: 204 KKAAVMLRDQFDGDVPTTIEGFMSLPGVGPKMGYLALQKSWAKIDGIGVDVHVDRLAKMW 263
K+ + +L+ + GD+P ++ ++LPGVGPKM +LA+ +W + GI VD HV R+A
Sbjct: 190 KQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRL 249
Query: 264 KWVDPKVCKTPEHTRKQLESWLPRSLWYEINPVLVGFGQVLCMPRSKRCELCLVNDICP 322
+W K K+PE TR LE WLPR LW+EIN +LVGFGQ C+P RC CL +CP
Sbjct: 250 RWT-KKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHACLNQALCP 307
>7298737 [L] KOG1921 Endonuclease III
Length = 308
Score = 152 bits (384), Expect = 8e-37
Identities = 82/229 (35%), Positives = 117/229 (50%), Gaps = 20/229 (8%)
Query: 94 VRFMRSMIKTPVDNVGCAMLPITINGVFGISKSNMQPKNYRXXXXXXXXXXXXTKDEVNA 153
+R MR+ PVD +GC + K R TKD+
Sbjct: 86 IRIMRNSRTAPVDTMGCHRC----------ADLKADSKTQRFQNLVALMLSSQTKDQTTY 135
Query: 154 KAMHNIMEYCMEELGDPEGITLGSLLKIEEKILDKEIYSVGFHTRKASYIKKAAVMLRDQ 213
+AM+ + + G+T + ++ L+ ++ V F+ KA Y+K+ +L D+
Sbjct: 136 EAMNRLKD---------RGLTPLKVKEMPVTELENLLHPVSFYKNKAKYLKQTVEILTDK 186
Query: 214 FDGDVPTTIEGFMSLPGVGPKMGYLALQKSWAKIDGIGVDVHVDRLAKMWKWVDPKVCKT 273
+ D+P ++ ++LPGVGPKM ++ + +W KI GIGVDVHV RL+ WV PK K
Sbjct: 187 YGSDIPDNVKDLVALPGVGPKMAHICMAVAWNKITGIGVDVHVHRLSNRLGWV-PKPTKE 245
Query: 274 PEHTRKQLESWLPRSLWYEINPVLVGFGQVLCMPRSKRCELCLVNDICP 322
PE TR LE WLP SLW E+N + VGFGQ +C P C CL DICP
Sbjct: 246 PEQTRVALEKWLPFSLWSEVNHLFVGFGQTICTPVKPNCGECLNKDICP 294
>CE03559 [L] KOG1921 Endonuclease III
Length = 259
Score = 151 bits (382), Expect = 1e-36
Identities = 83/226 (36%), Positives = 120/226 (52%), Gaps = 22/226 (9%)
Query: 97 MRSMIKTPVDNVGCAMLPITINGVFGISKSNMQPKNYRXXXXXXXXXXXXTKDEVNAKAM 156
MR + PVD +GC L + P +R T+DEVNA AM
Sbjct: 1 MRKDMIAPVDTMGCHKLADPLAA----------PPVHRFQVLVALMLSSQTRDEVNAAAM 50
Query: 157 HNIMEYCMEELGDPEGITLGSLLKIEEKILDKEIYSVGFHTRKASYIKKAAVMLRDQFDG 216
+ ++ G+++G +L+ + L+ + VGF+ RKA Y++K A +L+D F G
Sbjct: 51 KRLKDH---------GLSIGKILEFKVPDLETILCPVGFYKRKAVYLQKTAKILKDDFSG 101
Query: 217 DVPTTIEGFMSLPGVGPKMGYLALQKSWAKIDGIGVDVHVDRLAKMWKWVDPKVCKTPEH 276
D+P +++G +LPGVGPKM L +Q +W + GI VD HV R++ W+ TPE
Sbjct: 102 DIPDSLDGLCALPGVGPKMANLVMQIAWGECVGIAVDTHVHRISNRLGWIK---TSTPEK 158
Query: 277 TRKQLESWLPRSLWYEINPVLVGFGQVLCMPRSKRCELCLVNDICP 322
T+K LE LP+S W IN +LVGFGQ+ C P +C CL CP
Sbjct: 159 TQKALEILLPKSEWQPINHLLVGFGQMQCQPVRPKCGTCLCRFTCP 204
>At1g05900_2 [L] KOG1921 Endonuclease III
Length = 307
Score = 142 bits (357), Expect = 1e-33
Identities = 84/259 (32%), Positives = 121/259 (46%), Gaps = 39/259 (15%)
Query: 84 PSNFVSIYSKVRFMRSMIKTPVDNVGCAMLPITINGVFGISKSNMQPKNYRXXXXXXXXX 143
P N+ + +R M+ + PV+ V C + S + PK R
Sbjct: 46 PENWEKVLEGIRKMKPSEEAPVNAVECDR-----------TGSFLPPKERRFYVLIGTLL 94
Query: 144 XXXTKDEVNAKAMHNIMEYCMEELGDPEGITLGSLLKIEEKILDKEIYSVGFHTRKASYI 203
TK+ + A+ + + L PE I K +E + + IY VGF+TRKA+ +
Sbjct: 95 SSQTKEHITGAAVERLHQ---NGLLTPEAID-----KADESTIKELIYPVGFYTRKATNV 146
Query: 204 KKAAVMLRDQFDGDVPTTIEGFMSLPGVGPKMGYLALQKSWAKIDGIGVDVHVDRLAKMW 263
KK A + ++DGD+P T+E +SLPGVGPK+ +L L +W + GI VD HV R+
Sbjct: 147 KKVAKICLMEYDGDIPRTLEELLSLPGVGPKIAHLVLHVAWNDVQGICVDTHVHRICNRL 206
Query: 264 KWVDPKVCK--------------------TPEHTRKQLESWLPRSLWYEINPVLVGFGQV 303
WV K +PE TR L+ WLP+ W IN +LVGFGQ
Sbjct: 207 GWVSKPGTKQFAYLLLVTYLYFVLDQKTSSPEETRVALQQWLPKGEWVAINFLLVGFGQT 266
Query: 304 LCMPRSKRCELCLVNDICP 322
+C P C C + +ICP
Sbjct: 267 ICTPLRPHCGTCSITEICP 285
>ECU08g0880 [L] KOG1921 Endonuclease III
Length = 238
Score = 120 bits (302), Expect = 3e-27
Identities = 77/239 (32%), Positives = 121/239 (50%), Gaps = 21/239 (8%)
Query: 88 VSIYSKVRFMRSMIKTPVDNVGCAMLPITINGVFGISKSNMQPKNYRXXXXXXXXXXXXT 147
+ +Y +++ R I +PVD +GC++ P S + R T
Sbjct: 13 LGLYLEIKMQRKDIVSPVDTMGCSITP-----------SCRTEEERRFHILVSLLLSSQT 61
Query: 148 KDEVNAKAMHNIMEYCMEELG-DPE---GITLGSLLKIEEKILDKEIYSVGFHTRKASYI 203
KDEV +AM + + E D E G+T+ + + K +++ I VGFH RKA+ +
Sbjct: 62 KDEVTYEAMARLRKLLPESAATDGEARGGLTIERVANSDVKHINECIKKVGFHNRKAANL 121
Query: 204 KKAAVMLRDQFDGDVPTTIEGFMSLPGVGPKMGYLALQKSWAKIDGIGVDVHVDRLAKMW 263
KK A +LR++ +P ++ +SLPG+G KM L + + + GI VD HV R++
Sbjct: 122 KKIAEILREK---GLPREMKDLISLPGIGNKMALLYMSHACNRTVGISVDTHVHRISNRI 178
Query: 264 KWVDPKVCKTPEHTRKQLESWLPRSLWYEINPVLVGFGQVLCMPRSKRCELCLVNDICP 322
V + E TR++LE +PR W IN +LVGFGQ +C+ + RCE C + CP
Sbjct: 179 GLVRTR---DVESTRRELERVVPRKEWKTINNILVGFGQTICVAKRPRCEECCIRGRCP 234
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,887,896
Number of Sequences: 60738
Number of extensions: 895347
Number of successful extensions: 1949
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1922
Number of HSP's gapped (non-prelim): 9
length of query: 391
length of database: 30,389,216
effective HSP length: 108
effective length of query: 283
effective length of database: 23,829,512
effective search space: 6743751896
effective search space used: 6743751896
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)