ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2057 good R KOG0118 General function prediction only FOG: RRM domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2057 736463 734892 -524
(524 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL041c [R] KOG0118 FOG: RRM domain 414 e-115
SPAC16E8.06c [R] KOG0118 FOG: RRM domain 238 2e-62
CE28911 [R] KOG0118 FOG: RRM domain 92 2e-18
At5g46840 [R] KOG0118 FOG: RRM domain 87 5e-17
7298360 [R] KOG0118 FOG: RRM domain 76 1e-13
At5g65260 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily 63 9e-10
SPBC16E9.12c [A] KOG4209 Splicing factor RNPS1 SR protein superf... 63 1e-09
At5g51120 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily 62 2e-09
At5g10350 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily 62 2e-09
CE01888 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily 58 3e-08
YPR112c [R] KOG0110 RNA-binding protein (RRM superfamily) 58 4e-08
Hs4758876 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily 58 4e-08
CE01885 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily 56 1e-07
YIL061c [A] KOG0113 U1 small nuclear ribonucleoprotein (RRM supe... 55 3e-07
SPBC365.04c [R] KOG0118 FOG: RRM domain 55 3e-07
Hs14110420 [R] KOG0118 FOG: RRM domain 54 6e-07
Hs14110417 [R] KOG0118 FOG: RRM domain 54 6e-07
Hs14110414 [R] KOG0118 FOG: RRM domain 54 6e-07
CE17226 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily 54 6e-07
SPAC140.02 [K] KOG4210 Nuclear localization sequence binding pro... 54 8e-07
YIR001c [A] KOG4209 Splicing factor RNPS1 SR protein superfamily 53 1e-06
YNL175c [K] KOG4210 Nuclear localization sequence binding protein 53 1e-06
SPAC3G6.04 [K] KOG4210 Nuclear localization sequence binding pro... 53 1e-06
7304089 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily 52 3e-06
7301687 [R] KOG0118 FOG: RRM domain 52 3e-06
7301686 [R] KOG0118 FOG: RRM domain 52 3e-06
Hs4504445 [R] KOG0118 FOG: RRM domain 51 4e-06
Hs22067735 [A] KOG4205 RNA-binding protein musashi/mRNA cleavage... 51 4e-06
Hs14043070 [R] KOG0118 FOG: RRM domain 51 4e-06
Hs13650572 [R] KOG0118 FOG: RRM domain 51 4e-06
7301511 [R] KOG0118 FOG: RRM domain 51 4e-06
Hs22042102 [R] KOG0118 FOG: RRM domain 51 5e-06
Hs17433768 [R] KOG0118 FOG: RRM domain 50 6e-06
Hs13654587 [R] KOG0118 FOG: RRM domain 50 6e-06
Hs14731484 [A] KOG4205 RNA-binding protein musashi/mRNA cleavage... 50 8e-06
CE08254 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily 50 8e-06
At1g60000 [R] KOG0118 FOG: RRM domain 50 8e-06
>YOL041c [R] KOG0118 FOG: RRM domain
Length = 459
Score = 414 bits (1063), Expect = e-115
Identities = 240/473 (50%), Positives = 288/473 (60%), Gaps = 32/473 (6%)
Query: 64 SALNNLFGNSKSDAAGTSSIAALFSKP-NHVDERKVKSKARTVLTXXXXXXXXXXXXXXX 122
SA++NLFGN SS+ LFS +++ +VKSK RTVL
Sbjct: 3 SAIDNLFGNIDEKKI-ESSVDKLFSSSCGPINKLEVKSKTRTVLPDSKKRERAAEADQEE 61
Query: 123 XSASTVSEGVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVQYYSKVLGXXXXXXXXXXXX 182
AS V +YY+K+L
Sbjct: 62 KEAS--KPDVSDEQTEEVALPKVKKAKKSKRNDEDEDLEARYYAKLLNEEAEAEDDKPT- 118
Query: 183 XXXXXXXXXXXXATAVDKSSITGTESESAKVINLKEKELAKAERTIFIGNVPNEVITSKK 242
T D++S+ T + AK ++ KE EL KAERT+FIGN+ + VITSKK
Sbjct: 119 ------------VTKTDETSVPLTSA--AKKVDFKEDELEKAERTVFIGNILSTVITSKK 164
Query: 243 VYKEFKKLLSKDPRSXXXXXXXXXXXXXXXXSKTKDVKFNVESIRFRSIAFEEALPRKVA 302
VYKEFKKL +P K+ + +F +ESIRFRSI+F+EALPRKVA
Sbjct: 165 VYKEFKKLFGTNP--IAETEESGNEKEEESSKKSDNNEFAIESIRFRSISFDEALPRKVA 222
Query: 303 FVHQKLHKSRDSINAYAVYGSSNPVKIMCQYLNGKVFNDHHLRVDSVTHPSPHDKRRSVF 362
FV QK HKSRD+INAY VY + + V+ +C LN VF DHHLRVDSV HP+PHDK+RS+F
Sbjct: 223 FVQQKFHKSRDTINAYIVYKNKSAVRKICSNLNAVVFQDHHLRVDSVAHPAPHDKKRSIF 282
Query: 363 VGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALLLHEK 422
VGNLDFEE+EESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKD QSV+KALLL+EK
Sbjct: 283 VGNLDFEEIEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDLQSVNKALLLNEK 342
Query: 423 KIHE-----------GKKARKLRISRCKNMRKAQGNQSSLQNNKLNDQQRTKLGRAKKVL 471
+ KKARKLR+SRCKNM+K + L N L D QRT+ GRAKK+L
Sbjct: 343 PMKSQKQEDENTKKPTKKARKLRVSRCKNMKKGTTIGTGLDRNGLTDSQRTRAGRAKKIL 402
Query: 472 GKADRAKLGEELTIEGLRASKGETTPVLKRTKNRSKTGRVTKRSIAFKKQNAQ 524
GKADRA LG+E+TIEGLRA KGE + LK+ K RS TGRVTKRSIAFKK A+
Sbjct: 403 GKADRATLGQEITIEGLRAKKGEGSTHLKKKKQRSATGRVTKRSIAFKKAQAE 455
>SPAC16E8.06c [R] KOG0118 FOG: RRM domain
Length = 438
Score = 238 bits (606), Expect = 2e-62
Identities = 134/294 (45%), Positives = 183/294 (61%), Gaps = 35/294 (11%)
Query: 220 ELAKAERTIFIGNVPNEVITSKKVYKEFKKLLSKDPRSXXXXXXXXXXXXXXXXSKTKDV 279
EL K+++T+F+ N+P V+T+K YK+ L+K R
Sbjct: 158 ELEKSDKTVFVNNLPARVVTNKGDYKD----LTKHFRQFGA------------------- 194
Query: 280 KFNVESIRFRSIAFEEALPRKVAFVHQKLHKSRDSINAYAVYGSSNPVKIMCQYLNGKVF 339
V+SIRFRS+AF EA+PRKVAF +K H RD++NAY V+ S+ + LNG +F
Sbjct: 195 ---VDSIRFRSLAFSEAIPRKVAFFEKKFHSERDTVNAYIVFRDSSSARSALS-LNGTMF 250
Query: 340 NDHHLRVDSVTHPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMG 399
D HLRVDSV+HP P D +R VFVGNL FE EE LW++F CG I+YVRI+RD KTN+G
Sbjct: 251 MDRHLRVDSVSHPMPQDTKRCVFVGNLAFEAEEEPLWRYFGDCGSIDYVRIVRDPKTNLG 310
Query: 400 KGFAYVQFKDFQSVSKALLLHEKKIHEGKKARKLRISRCKNMRKAQGNQSSLQNNKLNDQ 459
KGFAY+QFKD V KALLL+EKK+ EG R LRI R K+ + +S ++ + +++
Sbjct: 311 KGFAYIQFKDTMGVDKALLLNEKKMPEG---RTLRIMRAKSTKP----KSITRSKRGDEK 363
Query: 460 QRTKLGRAKKVLGKADRAKLGEELTIEGLRASKGETTPVLKRTKNRSKTGRVTK 513
RT GRA+K++GKA A L +EL +EG RA GE P+ K+ N+ + R +
Sbjct: 364 TRTLQGRARKLIGKAGNALLQQELALEGHRAKPGE-NPLAKKKVNKKRKERAAQ 416
>CE28911 [R] KOG0118 FOG: RRM domain
Length = 394
Score = 92.0 bits (227), Expect = 2e-18
Identities = 77/237 (32%), Positives = 120/237 (50%), Gaps = 21/237 (8%)
Query: 283 VESIRFRSIA-FEEALPRKVAFVHQKLHKSRDSINAYAVYGSSNPVKIMCQYLNGKVFND 341
+ S+R R++ E L ++V + KL+ + S+ Y +G+ V+ +Y NG +D
Sbjct: 169 ISSVRMRNLLPANEKLTKRVTHLTGKLNDKQSSLTFYVKFGAEESVEKALKY-NGTKLDD 227
Query: 342 HHLRVDSV-THPSPHDKRRSVFVGNLDFEEVEESLWKHFEP-CGDIEYVRIIRDSKTNMG 399
H +RVD V + K ++FVGNL FE E++L F G +E VRI+RD T G
Sbjct: 228 HVIRVDKVGSKKKEFGKDMAIFVGNLPFEITEDALITFFSAQIGPVEAVRIVRDKDTGKG 287
Query: 400 KGFAYVQFKDFQSVSKALLLHEKKIHEGKKARKLRISRCKNMRKAQGNQSSLQNNKLNDQ 459
KGFA+V FK SVS AL + K+ + R LRI+ K M+K G+ + +Q K
Sbjct: 288 KGFAFVNFKQDSSVSLALSMETIKMEK----RDLRIT--KVMKK--GHLTKIQTAK---- 335
Query: 460 QRTKLGR--AKKVLGKADRAKLG---EELTIEGLRASKGETTPVLKRTKNRSKTGRV 511
+RT G+ ++ GK + K E T + R + ++ K +K GR+
Sbjct: 336 KRTSHGKKNQNEITGKLHKFKFSTKKERTTEQNDRRALKKSAKKAIAKKKAAKKGRL 392
>At5g46840 [R] KOG0118 FOG: RRM domain
Length = 501
Score = 87.4 bits (215), Expect = 5e-17
Identities = 88/309 (28%), Positives = 142/309 (45%), Gaps = 67/309 (21%)
Query: 222 AKAERTIFIGNVPNEVITSKKVYKEFKKLLSKDPRSXXXXXXXXXXXXXXXXSKTKDVKF 281
+K RT+F+GN+P +V K + KEF K
Sbjct: 167 SKLLRTVFVGNLPLKV-KKKVILKEFSKF------------------------------G 195
Query: 282 NVESIRFRSIAFEEAL-PRKVAFVHQKLHKSRDSINAYAVYGSSNPVKIMCQYLNGKVFN 340
VES+R RS+ ++ RK A + +++++ S++AY V+ + + N + +
Sbjct: 196 EVESVRIRSVPIVDSKRTRKGAIMLKQINEKASSVHAYVVFETEQSAAASLAH-NMSLID 254
Query: 341 DHHLRVDSVTHPSP----------HDKRRSVFVGNLDFEEVEESLWKHFEPCGD----IE 386
+H+RVD P +D +R+VF+GNL F+ +E +++ F + IE
Sbjct: 255 GNHVRVDRACPPRKKQKGHDDTHLYDPKRTVFMGNLPFDVKDEEVYQLFTGKSNLENSIE 314
Query: 387 YVRIIRDSKTNMGKGFAYVQFKDFQSVSKALLLHEKKIHEGKKARKLRISRCK--NMRKA 444
VR+IRD N+GKG AYV FK ++ + L KK + + R+LRISR K K
Sbjct: 315 AVRVIRDPHLNIGKGIAYVLFKTREAANLVL----KKGYLKLRERELRISRVKPDTPSKR 370
Query: 445 QGNQSSLQNNKLNDQQRTKLGRAKKVLGKADRAKLGEELTIEGLRASKG---ETTPVLK- 500
+ N S + Q+ K+ GKA+ L+ +G+RASK + TP K
Sbjct: 371 KSNPSEAYSPAQKRLQKDKVVTPTPT-GKAN-------LSYQGVRASKSGDDKKTPYQKS 422
Query: 501 --RTKNRSK 507
+TK R +
Sbjct: 423 SAQTKMRPR 431
>7298360 [R] KOG0118 FOG: RRM domain
Length = 435
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/260 (30%), Positives = 114/260 (43%), Gaps = 37/260 (14%)
Query: 283 VESIRFRSIAFEEALPRKVAFVHQKLHKSRDSINAYAVYGSSNPVKIMCQYLNGKVFNDH 342
V+SIR R+ K F H K K S+NAY V + LNG F ++
Sbjct: 181 VQSIRLRTAG------GKQLFKH-KQRKVAGSLNAYVVLEKPE-IAQQALALNGSEFKEN 232
Query: 343 HLRVDSVT-----------HPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRII 391
HLRV + PS D +R++FVG+L + EE L + F CG+I+Y+R +
Sbjct: 233 HLRVTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCL 292
Query: 392 RDSKTNMGKGFAYVQFKDFQSVSKAL-----LLHEKKIH-EGKKARKLRISRCKNMRKAQ 445
+D KG AYV F+ +V AL LL ++ I+ E + +KL + ++ A
Sbjct: 293 QDGDKGC-KGVAYVCFQKPDAVGLALELNQTLLDDRPINVERYQVKKLGAKQVRDAAAAS 351
Query: 446 GNQSSLQNNKLNDQQRTKLGRAKKVLGKADRAKLGEELTIEGLRASKGETTPVLKRTKNR 505
+ K +Q AKK L K K G+E G +G T K+++ R
Sbjct: 352 AASKTSSKTKAKNQNS---AGAKKRLDK----KKGKE---NGSLKKEGAPTGQKKKSEYR 401
Query: 506 S-KTGRVTKRSIAFKKQNAQ 524
K + K KK N Q
Sbjct: 402 GVKVDGIKKAKKPKKKSNDQ 421
>At5g65260 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 220
Score = 63.2 bits (152), Expect = 9e-10
Identities = 32/76 (42%), Positives = 51/76 (67%), Gaps = 2/76 (2%)
Query: 359 RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALL 418
RSVFVGN+D+ E + +HF+ CG + V I+ D K KGFAYV+F + ++V +AL
Sbjct: 92 RSVFVGNVDYACTPEEVQQHFQTCGTVHRVTILTD-KFGQPKGFAYVEFVEVEAVQEALQ 150
Query: 419 LHEKKIHEGKKARKLR 434
L+E ++H G++ + L+
Sbjct: 151 LNESELH-GRQLKVLQ 165
>SPBC16E9.12c [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 166
Score = 62.8 bits (151), Expect = 1e-09
Identities = 33/86 (38%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 345 RVDSVTHPSPHDKR----RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGK 400
++D+ T +DK +SV+VGN+D+ E L HF CG + V I+ D T K
Sbjct: 37 QLDNETEALRNDKESIDAQSVYVGNVDYSVTPEELQSHFASCGSVNRVTILCDKFTGHPK 96
Query: 401 GFAYVQFKDFQSVSKALLLHEKKIHE 426
GFAY++F + V ALLL+ +HE
Sbjct: 97 GFAYIEFSEPSLVPNALLLNGSMLHE 122
>At5g51120 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 267
Score = 62.4 bits (150), Expect = 2e-09
Identities = 30/88 (34%), Positives = 53/88 (60%), Gaps = 1/88 (1%)
Query: 359 RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALL 418
RS++VGN+D+ E + +HF+ CG + V I+ D K KGFAYV+F + ++V +L+
Sbjct: 103 RSIYVGNVDYACTPEEVQQHFQSCGTVNRVTILTD-KFGQPKGFAYVEFVEVEAVQNSLI 161
Query: 419 LHEKKIHEGKKARKLRISRCKNMRKAQG 446
L+E ++H + + + MR+ +G
Sbjct: 162 LNESELHGRQIKVSAKRTNVPGMRQFRG 189
>At5g10350 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 217
Score = 62.0 bits (149), Expect = 2e-09
Identities = 32/78 (41%), Positives = 50/78 (64%), Gaps = 5/78 (6%)
Query: 359 RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALL 418
RSV+VGN+D+ E + HF+ CG + V I+ D K KGFAYV+F + ++V +AL
Sbjct: 89 RSVYVGNVDYACTPEEVQLHFQTCGTVNRVTILMD-KFGQPKGFAYVEFVEVEAVQEALQ 147
Query: 419 LHEKKIHEGKKARKLRIS 436
L+E ++H R+L++S
Sbjct: 148 LNESELH----GRQLKVS 161
>CE01888 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 237
Score = 58.2 bits (139), Expect = 3e-08
Identities = 28/82 (34%), Positives = 46/82 (55%), Gaps = 4/82 (4%)
Query: 343 HLRVDSVTHPSPHDKR----RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNM 398
HL + P+ +++ +SVF+GN+DF E + +HF+ CG I I +D T
Sbjct: 81 HLESAAYVPPTEEEQKAIDAKSVFIGNVDFNSTIEEIEEHFKGCGQIVKTTIPKDKFTKK 140
Query: 399 GKGFAYVQFKDFQSVSKALLLH 420
K FAY++F D S+ AL+++
Sbjct: 141 QKNFAYIEFDDSSSIENALVMN 162
>YPR112c [R] KOG0110 RNA-binding protein (RRM superfamily)
Length = 887
Score = 57.8 bits (138), Expect = 4e-08
Identities = 41/131 (31%), Positives = 61/131 (46%), Gaps = 19/131 (14%)
Query: 361 VFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALLLH 420
+F+ N+ + EE K F P G++E V + D++T KGFAYV FKD ++ A +
Sbjct: 347 LFLRNILYTSKEEDFRKLFSPFGELEEVHVALDTRTGQSKGFAYVLFKDSKNAVNAYVEL 406
Query: 421 EKKIHEG----------KKARKLRISRCKNM---------RKAQGNQSSLQNNKLNDQQR 461
+K+I +G KK+ +L KNM RKA ++ + N L Q
Sbjct: 407 DKQIFQGRLLHILPGEEKKSHRLDEFDLKNMPLKKQKELKRKAAASRQTFSWNSLYMNQD 466
Query: 462 TKLGRAKKVLG 472
LG LG
Sbjct: 467 AVLGSVAAKLG 477
>Hs4758876 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 306
Score = 57.8 bits (138), Expect = 4e-08
Identities = 27/63 (42%), Positives = 38/63 (59%)
Query: 359 RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALL 418
RS++VGN+D+ E L HF CG + V I+ D + KGFAY++F D +SV +L
Sbjct: 172 RSIYVGNVDYGATAEELEAHFHGCGSVNRVTILCDKFSGHPKGFAYIEFSDKESVRTSLA 231
Query: 419 LHE 421
L E
Sbjct: 232 LDE 234
>CE01885 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 197
Score = 56.2 bits (134), Expect = 1e-07
Identities = 25/62 (40%), Positives = 38/62 (60%)
Query: 359 RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALL 418
+SVF+GN+DF E + +HF+ CG I I +D T K FAY++F D S+ AL+
Sbjct: 61 KSVFIGNVDFNSTIEEVEEHFKGCGHIVRTTIPKDKFTKKQKNFAYIEFDDSSSIENALV 120
Query: 419 LH 420
++
Sbjct: 121 MN 122
>YIL061c [A] KOG0113 U1 small nuclear ribonucleoprotein (RRM superfamily)
Length = 300
Score = 54.7 bits (130), Expect = 3e-07
Identities = 27/77 (35%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Query: 351 HPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDF 410
H D R++F+G L ++ E L K+F G+IE +RI++D T KG+A++ FKD
Sbjct: 99 HIKDTDPYRTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKD- 157
Query: 411 QSVSKALLLHEKKIHEG 427
+S + E +H G
Sbjct: 158 -PISSKMAFKEIGVHRG 173
>SPBC365.04c [R] KOG0118 FOG: RRM domain
Length = 233
Score = 54.7 bits (130), Expect = 3e-07
Identities = 59/229 (25%), Positives = 105/229 (45%), Gaps = 31/229 (13%)
Query: 280 KFNVESIRFRSIAFE------EALPRKVAFVHQKLHK------SRDSINAYAVYGSSNPV 327
K ++S+ +RS F+ E +KV +++L K SRD + + S++
Sbjct: 7 KKKLKSLEYRSKKFDKKSQSLEEHEKKVQQKNEELEKKAADKISRDELPEKQLAQSNDKD 66
Query: 328 KIMCQYLNGKVFNDHHLRVDSVTHPSPHDKRRSV-FVGNLDFEEVEESLWKHFEPCGDIE 386
K V N H + S ++ R+ + FVGNL + E+L HF+ G +
Sbjct: 67 K-------HSVSNPPHKTLKSKRQKGKNNDRKVILFVGNLPKDSSVETLQLHFKRAGQVP 119
Query: 387 YVRIIRDSKTNMGKGFAYVQFKDFQS--VSKALLLHEKKIHEGKKARKLRISRCK---NM 441
VRI D + KG+A+V+F + ++ +SKAL H H K RK+ I
Sbjct: 120 SVRIPTDKTSGRQKGYAFVEFINPKTDVISKALKFH----HTIYKERKINIELTAGGGGK 175
Query: 442 RKAQGNQSSLQNNKLNDQQRTKLGRAKKVLGKADRAKLGEELTIEGLRA 490
+A+ N+ +N K ++ R ++ ++ G+ A+ + + EGL +
Sbjct: 176 TEARMNKIKEKNRKWKEEMRQRVASEEQQAGEEKMAR--KAVADEGLES 222
>Hs14110420 [R] KOG0118 FOG: RRM domain
Length = 355
Score = 53.9 bits (128), Expect = 6e-07
Identities = 32/113 (28%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 334 LNGKVFNDHHLRVDSVTHPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRD 393
LNGKV + + P + +FVG L + EE + ++F G++E + + D
Sbjct: 162 LNGKVIDPKRAKAMKTKEPV-----KKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD 216
Query: 394 SKTNMGKGFAYVQFKDFQSVSKALLLHEKKIHE-GKKARKLRISRCKNMRKAQ 445
+KTN +GF ++ FK+ + V K + EKK H G +++++ K + Q
Sbjct: 217 NKTNKRRGFCFITFKEEEPVKKIM---EKKYHNVGLSKCEIKVAMSKEQYQQQ 266
>Hs14110417 [R] KOG0118 FOG: RRM domain
Length = 336
Score = 53.9 bits (128), Expect = 6e-07
Identities = 32/113 (28%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 334 LNGKVFNDHHLRVDSVTHPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRD 393
LNGKV + + P + +FVG L + EE + ++F G++E + + D
Sbjct: 143 LNGKVIDPKRAKAMKTKEPV-----KKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD 197
Query: 394 SKTNMGKGFAYVQFKDFQSVSKALLLHEKKIHE-GKKARKLRISRCKNMRKAQ 445
+KTN +GF ++ FK+ + V K + EKK H G +++++ K + Q
Sbjct: 198 NKTNKRRGFCFITFKEEEPVKKIM---EKKYHNVGLSKCEIKVAMSKEQYQQQ 247
>Hs14110414 [R] KOG0118 FOG: RRM domain
Length = 306
Score = 53.9 bits (128), Expect = 6e-07
Identities = 32/113 (28%), Positives = 57/113 (50%), Gaps = 9/113 (7%)
Query: 334 LNGKVFNDHHLRVDSVTHPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRD 393
LNGKV + + P + +FVG L + EE + ++F G++E + + D
Sbjct: 162 LNGKVIDPKRAKAMKTKEPV-----KKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD 216
Query: 394 SKTNMGKGFAYVQFKDFQSVSKALLLHEKKIHE-GKKARKLRISRCKNMRKAQ 445
+KTN +GF ++ FK+ + V K + EKK H G +++++ K + Q
Sbjct: 217 NKTNKRRGFCFITFKEEEPVKKIM---EKKYHNVGLSKCEIKVAMSKEQYQQQ 266
>CE17226 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 729
Score = 53.9 bits (128), Expect = 6e-07
Identities = 29/94 (30%), Positives = 50/94 (52%), Gaps = 4/94 (4%)
Query: 359 RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALL 418
RSV+VGN+D++ + +HF CG + V I +D T K FA+V+F+ +SV AL+
Sbjct: 46 RSVYVGNVDWKSTVSEIEEHFAVCGKVARVTIPKDKFTGYQKNFAFVEFQKLESVQLALV 105
Query: 419 LHEKKIHEGKKARKLRISRCKNMRKAQGNQSSLQ 452
L + RK+ ++ + + G ++ Q
Sbjct: 106 LSGTMF----RNRKIMVTLKRTNKPGMGRTATAQ 135
>SPAC140.02 [K] KOG4210 Nuclear localization sequence binding protein
Length = 500
Score = 53.5 bits (127), Expect = 8e-07
Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 5/71 (7%)
Query: 347 DSVTHPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQ 406
D ++ PS +VFVGNL F E+ L F CGDI+ +R+ D ++ KGF YV
Sbjct: 359 DQLSEPSD-----TVFVGNLSFNATEDDLSTAFGGCGDIQSIRLPTDPQSGRLKGFGYVT 413
Query: 407 FKDFQSVSKAL 417
F D S K +
Sbjct: 414 FSDIDSAKKCV 424
>YIR001c [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 250
Score = 53.1 bits (126), Expect = 1e-06
Identities = 32/106 (30%), Positives = 54/106 (50%), Gaps = 14/106 (13%)
Query: 332 QYLNGKVFNDHHLRVDSVTHPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRII 391
Q L+ + + H L DS RS+FVGN+ + E + HF+ CG I+ + ++
Sbjct: 47 QKLSKEEKHAHQLEADS----------RSIFVGNITPDVTPEQIEDHFKDCGQIKRITLL 96
Query: 392 RDSKTNMGKGFAYVQFKDFQSVSKALLLHEKKIHEGKKARKLRISR 437
D T KG+ Y++F+ KAL L+ ++ K +K+ +SR
Sbjct: 97 YDRNTGTPKGYGYIEFESPAYREKALQLNGGEL----KGKKIAVSR 138
>YNL175c [K] KOG4210 Nuclear localization sequence binding protein
Length = 403
Score = 52.8 bits (125), Expect = 1e-06
Identities = 35/123 (28%), Positives = 61/123 (49%), Gaps = 11/123 (8%)
Query: 347 DSVTHPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQ 406
D + S + R +FVGNL F+ ++ L KHF+ CGDI +R+ + KGFA++
Sbjct: 227 DDLVAMSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFEDSGKCKGFAFID 286
Query: 407 FKDFQSVSKALLLHE-KKI---------HEGKKARKLRISRCKNMRKAQGNQSSLQNNKL 456
FK+ + + L +KI E + R++R + +N+ + + + NNK
Sbjct: 287 FKNEEGSTNELKDKSCRKIAGRPLRMEYGEDRSKRQVR-KKVENVSRNNSSSFDISNNKG 345
Query: 457 NDQ 459
D+
Sbjct: 346 YDR 348
>SPAC3G6.04 [K] KOG4210 Nuclear localization sequence binding protein
Length = 369
Score = 52.8 bits (125), Expect = 1e-06
Identities = 33/112 (29%), Positives = 53/112 (46%), Gaps = 6/112 (5%)
Query: 361 VFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALLL- 419
+FVGNLDFE + L +HF G I VR++ T KGF +V F D + KA+ L
Sbjct: 230 LFVGNLDFETTDADLKEHFGQVGQIRRVRLMTFEDTGKCKGFGFVDFPDIDTCMKAMELG 289
Query: 420 -HEKKIHEGKKARKLRISRCKNMRKAQGNQSSLQNNKLNDQQRTKLGRAKKV 470
+ ++ G+ K ++ R + N + L + + RA+K+
Sbjct: 290 HNSWRLEYGEDRSKRMRNKSPMARSGRFNDA----ESLGQEDKPNFKRARKI 337
>7304089 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 224
Score = 51.6 bits (122), Expect = 3e-06
Identities = 26/63 (41%), Positives = 36/63 (56%)
Query: 359 RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALL 418
RSV+VGN+D+ E L HF CG I V I+ + KGFAY++F + V AL
Sbjct: 96 RSVYVGNVDYGASAEELEAHFHGCGTINRVTILCNKADGHPKGFAYIEFGSKEFVETALA 155
Query: 419 LHE 421
++E
Sbjct: 156 MNE 158
>7301687 [R] KOG0118 FOG: RRM domain
Length = 365
Score = 51.6 bits (122), Expect = 3e-06
Identities = 28/96 (29%), Positives = 48/96 (49%), Gaps = 14/96 (14%)
Query: 340 NDHHLRVDSVTHPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMG 399
+D DS+T P + R +F+G LD+ +E+L HFE G+I V +++D +T
Sbjct: 15 HDDDFPQDSITEP---EHMRKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPRTKRS 71
Query: 400 KGFAYVQFKDFQSVSKALLLHEKKIHEGKKARKLRI 435
+GF ++ + H I E +K+R +I
Sbjct: 72 RGFGFITYS-----------HSSMIDEAQKSRPHKI 96
>7301686 [R] KOG0118 FOG: RRM domain
Length = 363
Score = 51.6 bits (122), Expect = 3e-06
Identities = 29/101 (28%), Positives = 49/101 (47%), Gaps = 14/101 (13%)
Query: 335 NGKVFNDHHLRVDSVTHPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDS 394
NG+ DS+T P + R +F+G LD+ +E+L HFE G+I V +++D
Sbjct: 9 NGQNEEQDDFPQDSITEP---EHMRKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDP 65
Query: 395 KTNMGKGFAYVQFKDFQSVSKALLLHEKKIHEGKKARKLRI 435
+T +GF ++ + H I E +K+R +I
Sbjct: 66 RTKRSRGFGFITYS-----------HSSMIDEAQKSRPHKI 95
>Hs4504445 [R] KOG0118 FOG: RRM domain
Length = 320
Score = 51.2 bits (121), Expect = 4e-06
Identities = 27/91 (29%), Positives = 43/91 (46%)
Query: 352 PSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQ 411
P ++ R +F+G L FE +ESL HFE G + ++RD T +GF +V + +
Sbjct: 7 PKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVE 66
Query: 412 SVSKALLLHEKKIHEGKKARKLRISRCKNMR 442
V A+ K+ K +SR + R
Sbjct: 67 EVDAAMNARPHKVDGRVVEPKRAVSREDSQR 97
>Hs22067735 [A] KOG4205 RNA-binding protein musashi/mRNA cleavage and
polyadenylation factor I complex subunit HRP1
Length = 268
Score = 51.2 bits (121), Expect = 4e-06
Identities = 27/91 (29%), Positives = 43/91 (46%)
Query: 352 PSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQ 411
P ++ R +F+G L FE +ESL HFE G + ++RD T +GF +V + +
Sbjct: 7 PKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVE 66
Query: 412 SVSKALLLHEKKIHEGKKARKLRISRCKNMR 442
V A+ K+ K +SR + R
Sbjct: 67 EVDAAMNARPHKVDGRVVEPKRAVSREDSQR 97
>Hs14043070 [R] KOG0118 FOG: RRM domain
Length = 372
Score = 51.2 bits (121), Expect = 4e-06
Identities = 27/91 (29%), Positives = 43/91 (46%)
Query: 352 PSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQ 411
P ++ R +F+G L FE +ESL HFE G + ++RD T +GF +V + +
Sbjct: 7 PKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVE 66
Query: 412 SVSKALLLHEKKIHEGKKARKLRISRCKNMR 442
V A+ K+ K +SR + R
Sbjct: 67 EVDAAMNARPHKVDGRVVEPKRAVSREDSQR 97
>Hs13650572 [R] KOG0118 FOG: RRM domain
Length = 321
Score = 51.2 bits (121), Expect = 4e-06
Identities = 27/91 (29%), Positives = 43/91 (46%)
Query: 352 PSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQ 411
P ++ R +F+G L FE +ESL HFE G + ++RD T +GF +V + +
Sbjct: 7 PKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVE 66
Query: 412 SVSKALLLHEKKIHEGKKARKLRISRCKNMR 442
V A+ K+ K +SR + R
Sbjct: 67 EVDAAMNARPHKVDGRVVEPKRAVSREDSQR 97
>7301511 [R] KOG0118 FOG: RRM domain
Length = 471
Score = 51.2 bits (121), Expect = 4e-06
Identities = 34/111 (30%), Positives = 57/111 (50%), Gaps = 7/111 (6%)
Query: 359 RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALL 418
+ +FVG L EE L ++F G++ V+++ D T +GFA+V+F D+ +V KA+L
Sbjct: 123 KKLFVGGLKDNHDEECLREYFLQFGNVVSVKLLTDKTTGKRRGFAFVEFDDYDAVDKAIL 182
Query: 419 LHEKKIHEGK----KARKLRISRCKNMRKAQGNQSSLQNNKLNDQQRTKLG 465
KK H K +K + K ++ G ++ LN QQ+ + G
Sbjct: 183 ---KKQHAIKYVHVDVKKSIYNLDKKEKQQPGGLANAIKPSLNQQQQQQGG 230
>Hs22042102 [R] KOG0118 FOG: RRM domain
Length = 378
Score = 50.8 bits (120), Expect = 5e-06
Identities = 25/86 (29%), Positives = 43/86 (49%)
Query: 352 PSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQ 411
P ++ R +F+G L FE ++SL +HFE G + ++RD +T +GF +V + +
Sbjct: 28 PKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVE 87
Query: 412 SVSKALLLHEKKIHEGKKARKLRISR 437
V A+ K+ K +SR
Sbjct: 88 EVDAAMCARPHKVDGRVVEPKRAVSR 113
>Hs17433768 [R] KOG0118 FOG: RRM domain
Length = 238
Score = 50.4 bits (119), Expect = 6e-06
Identities = 23/67 (34%), Positives = 37/67 (54%)
Query: 352 PSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQ 411
P H + +FVG + + E L +FE CG +E + II D + +GFA+V F D+
Sbjct: 53 PGAHLTVKKIFVGGIKEDTEEHHLRDYFELCGKMELIEIITDRGSGKKRGFAFVTFDDYD 112
Query: 412 SVSKALL 418
S+ K ++
Sbjct: 113 SMDKTVI 119
>Hs13654587 [R] KOG0118 FOG: RRM domain
Length = 320
Score = 50.4 bits (119), Expect = 6e-06
Identities = 27/91 (29%), Positives = 43/91 (46%)
Query: 352 PSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQ 411
P ++ R +F+G L FE +ESL HFE G + ++RD T +GF +V + +
Sbjct: 7 PKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVE 66
Query: 412 SVSKALLLHEKKIHEGKKARKLRISRCKNMR 442
V A+ K+ K +SR + R
Sbjct: 67 EVDAAMNTTPHKVDGRVVEPKRAVSREDSQR 97
>Hs14731484 [A] KOG4205 RNA-binding protein musashi/mRNA cleavage and
polyadenylation factor I complex subunit HRP1
Length = 320
Score = 50.1 bits (118), Expect = 8e-06
Identities = 27/91 (29%), Positives = 43/91 (46%)
Query: 352 PSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQ 411
P ++ R +F+G L FE +ESL HFE G + ++RD T GF +V + +
Sbjct: 7 PKEPEQLRKLFIGGLSFETTDESLRSHFEQRGTLTDCVVMRDPNTKCSTGFGFVTYATVK 66
Query: 412 SVSKALLLHEKKIHEGKKARKLRISRCKNMR 442
V A+ +K+ K +SR + R
Sbjct: 67 EVEAAMNARPQKVDGRVVEPKRAVSREDSQR 97
>CE08254 [A] KOG4209 Splicing factor RNPS1 SR protein superfamily
Length = 205
Score = 50.1 bits (118), Expect = 8e-06
Identities = 23/61 (37%), Positives = 36/61 (58%)
Query: 359 RSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALL 418
+SV+VGN+D+ E + +HF CG + V I D + KGFAYV+F + + + AL
Sbjct: 78 KSVYVGNVDYGATAEEIEQHFHGCGSVSRVTIQCDRFSGHPKGFAYVEFTEKEGMQNALA 137
Query: 419 L 419
+
Sbjct: 138 M 138
>At1g60000 [R] KOG0118 FOG: RRM domain
Length = 258
Score = 50.1 bits (118), Expect = 8e-06
Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)
Query: 278 DVKFNVESIRFRSIAFEEALPRKVAFVHQKLHKSRDSINAYAVYGSSNPVKIMCQYLNGK 337
++ +NV+S I + A P V ++ + + A+ + I+ L+G
Sbjct: 91 NLPYNVDSATLAQIIQDFANPELVEVLYNR-DTGQSRGFAFVTMSNVEDCNIIIDNLDGT 149
Query: 338 VFNDHHLRVDSVTHPSPH------DKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRII 391
+ L+V+ P P+ + +FVGNL + ESL F CGD+ R++
Sbjct: 150 EYLGRALKVNFADKPKPNKEPLYPETEHKLFVGNLSWTVTSESLAGAFRECGDVVGARVV 209
Query: 392 RDSKTNMGKGFAYVQFKDFQSVSKAL 417
D T +G+ +V + + AL
Sbjct: 210 FDGDTGRSRGYGFVCYSSKAEMETAL 235
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.130 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,466,581
Number of Sequences: 60738
Number of extensions: 953763
Number of successful extensions: 3604
Number of sequences better than 1.0e-05: 37
Number of HSP's better than 0.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3546
Number of HSP's gapped (non-prelim): 64
length of query: 524
length of database: 30,389,216
effective HSP length: 111
effective length of query: 413
effective length of database: 23,647,298
effective search space: 9766334074
effective search space used: 9766334074
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)