ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2084 good E KOG0053 Amino acid transport and metabolism Cystathionine beta-lyases/cystathionine gamma-synthases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2084 742468 743640 391
(391 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YAL012w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 630 0.0
7302582 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 353 2e-97
HsM4503125 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 351 1e-96
Hs21361334 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 351 1e-96
CE07648 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 342 7e-94
CE15884 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 329 5e-90
At3g57050 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 253 3e-67
At3g01120 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 218 1e-56
CE17400 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 201 1e-51
At1g33320 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 189 8e-48
YGL184c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 182 6e-46
SPBC428.11 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 182 1e-45
YLR303w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 174 3e-43
At1g64660 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 137 4e-32
YHR112c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 128 2e-29
SPAC23A1.14c [E] KOG0053 Cystathionine beta-lyases/cystathionine... 124 2e-28
YFR055w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 113 4e-25
SPCC11E10.01 [E] KOG0053 Cystathionine beta-lyases/cystathionine... 49 1e-05
>YAL012w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 394
Score = 630 bits (1626), Expect = 0.0
Identities = 319/394 (80%), Positives = 350/394 (87%), Gaps = 3/394 (0%)
Query: 1 MGLLPTDKFATKAIHAGTHVDVHGSVIEPISLSTTFKQSAPAQPIGEYEYSRSQNPNRKN 60
M L +DKFATKAIHAG HVDVHGSVIEPISLSTTFKQS+PA PIG YEYSRSQNPNR+N
Sbjct: 1 MTLQESDKFATKAIHAGEHVDVHGSVIEPISLSTTFKQSSPANPIGTYEYSRSQNPNREN 60
Query: 61 LEDAIAALENGKYGLAFSSGSATTAVILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGV 120
LE A+AALEN +YGLAFSSGSATTA ILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGV
Sbjct: 61 LERAVAALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGV 120
Query: 121 ETTFTNNLVAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAK--SINKDILLVVDN 178
ET+FTN+L+ +LP LIKENTKLVWIETPTNPTLKVTDI+ VA K + +D++LVVDN
Sbjct: 121 ETSFTNDLLNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVILVVDN 180
Query: 179 TFLSPYLSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIPS 238
TFLSPY+SNPLNFGADIVVHSATKYINGHSDVVLGVLATN+K +YE+LQFLQNAIGAIPS
Sbjct: 181 TFLSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPS 240
Query: 239 PFDSWLVHRGVKTLHLRVRQASLSAHKIAEFLSSN-ENVIAVNYPGLPTHESYAVVKKQH 297
PFD+WL HRG+KTLHLRVRQA+LSA+KIAEFL+++ ENV+AVNYPGL TH +Y VV KQH
Sbjct: 241 PFDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQH 300
Query: 298 RDALGGGMISFRIKGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQRE 357
RDALGGGMISFRIKGGAE ESLGGIESLLEVPAVMTHGGIPKE RE
Sbjct: 301 RDALGGGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPKEARE 360
Query: 358 ASGVYDDLVRLSIGIEDTDDLLEDIKQALASASN 391
ASGV+DDLVR+S+GIEDTDDLLEDIKQAL A+N
Sbjct: 361 ASGVFDDLVRISVGIEDTDDLLEDIKQALKQATN 394
>7302582 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 393
Score = 353 bits (906), Expect = 2e-97
Identities = 190/386 (49%), Positives = 248/386 (64%), Gaps = 8/386 (2%)
Query: 9 FATKAIHAGTHVDVHGS--VIEPISLSTTFKQSAPAQPIGEYEYSRSQNPNRKNLEDAIA 66
FATK+IH+G D S VI PISLSTTFKQ AP + G YEYSRS NP R LE A
Sbjct: 10 FATKSIHSGQSPDQWKSAAVIPPISLSTTFKQDAPGEHRG-YEYSRSGNPTRNVLETCFA 68
Query: 67 ALENGKYGLAFSSGSATTAVILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVETTFTN 126
AL+N KYGL FSSG T +L L G H + DVYGGT+R +VA G+ TF +
Sbjct: 69 ALDNAKYGLTFSSGLGATTAVLTMLSSGDHIIMGDDVYGGTNRLIRQVATRLGISATFVD 128
Query: 127 NLVAEL-PSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVDNTFLSPYL 185
+L S IK TKLVWIE+PTNP +KV DIE +A+ + +DI+L VDNTFL+ Y
Sbjct: 129 PTKLDLIKSSIKPETKLVWIESPTNPLVKVADIEAIAQLVHGVREDIVLAVDNTFLTSYF 188
Query: 186 SNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIPSPFDSWLV 245
PL GAD+V +S TKY+NGH+DVV+G + N + +Y+ L+FLQNA+G +PSPFD + V
Sbjct: 189 QRPLELGADLVCYSLTKYMNGHTDVVMGGITMNSEKLYKSLKFLQNAVGIVPSPFDCYQV 248
Query: 246 HRGVKTLHLRVRQASLSAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQHRDALG-GG 304
+R +KTL LR+ Q +A K+A++L +N V V +P LP+H + + KQ A G G
Sbjct: 249 NRSLKTLSLRMEQHQKNALKVAKYLETNPFVEKVLHPSLPSHPQHKIALKQ---AYGYSG 305
Query: 305 MISFRIKGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQREASGVYDD 364
+ SF IKG + ESLGG ESL E+P++MTH +P E R+ G+ D
Sbjct: 306 VFSFYIKGELKHSSAFLKALKVFTLAESLGGYESLAELPSIMTHASVPAEDRKTLGITDG 365
Query: 365 LVRLSIGIEDTDDLLEDIKQALASAS 390
LVRLS+G+ED DDL++D++QAL AS
Sbjct: 366 LVRLSVGLEDADDLIKDLEQALEIAS 391
>HsM4503125 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 405
Score = 351 bits (900), Expect = 1e-96
Identities = 193/392 (49%), Positives = 257/392 (65%), Gaps = 8/392 (2%)
Query: 2 GLLPT-DKFATKAIHAGTHVDVHGS--VIEPISLSTTFKQSAPAQPIGEYEYSRSQNPNR 58
G LP FAT+AIH G + S V+ PISLSTTFKQ AP Q G +EYSRS NP R
Sbjct: 10 GFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSG-FEYSRSGNPTR 68
Query: 59 KNLEDAIAALENGKYGLAFSSGSATTAVILQSLPQGSHAVSIGDVYGGTHRYFTKVANAH 118
LE A+AAL+ KY LAF+SG A T I L G + + DVYGGT+RYF +VA+
Sbjct: 69 NCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF 128
Query: 119 GVETTFTN-NLVAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVD 177
G++ +F + + + L + I TKLVWIETPTNPT KV DIE A + DI+LVVD
Sbjct: 129 GLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHK-HGDIILVVD 187
Query: 178 NTFLSPYLSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIP 237
NTF+SPY PL GADI ++SATKY+NGHSDVV+G+++ N + ++ +L+FLQN++GA+P
Sbjct: 188 NTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVP 247
Query: 238 SPFDSWLVHRGVKTLHLRVRQASLSAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQH 297
SP D +L +RG+KTLH+R+ + + +A+FL SN V V YPGLP+H + +VK+Q
Sbjct: 248 SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQC 307
Query: 298 RDALGGGMISFRIKGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQRE 357
GM++F IKG + ESLGG ESL E+PA+MTH + K R+
Sbjct: 308 TGCT--GMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRD 365
Query: 358 ASGVYDDLVRLSIGIEDTDDLLEDIKQALASA 389
G+ D L+RLS+G+ED +DLLED+ QAL +A
Sbjct: 366 VLGISDTLIRLSVGLEDEEDLLEDLDQALKAA 397
>Hs21361334 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 405
Score = 351 bits (900), Expect = 1e-96
Identities = 193/392 (49%), Positives = 257/392 (65%), Gaps = 8/392 (2%)
Query: 2 GLLPT-DKFATKAIHAGTHVDVHGS--VIEPISLSTTFKQSAPAQPIGEYEYSRSQNPNR 58
G LP FAT+AIH G + S V+ PISLSTTFKQ AP Q G +EYSRS NP R
Sbjct: 10 GFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSG-FEYSRSGNPTR 68
Query: 59 KNLEDAIAALENGKYGLAFSSGSATTAVILQSLPQGSHAVSIGDVYGGTHRYFTKVANAH 118
LE A+AAL+ KY LAF+SG A T I L G + + DVYGGT+RYF +VA+
Sbjct: 69 NCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF 128
Query: 119 GVETTFTN-NLVAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVD 177
G++ +F + + + L + I TKLVWIETPTNPT KV DIE A + DI+LVVD
Sbjct: 129 GLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHK-HGDIILVVD 187
Query: 178 NTFLSPYLSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIP 237
NTF+SPY PL GADI ++SATKY+NGHSDVV+G+++ N + ++ +L+FLQN++GA+P
Sbjct: 188 NTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVP 247
Query: 238 SPFDSWLVHRGVKTLHLRVRQASLSAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQH 297
SP D +L +RG+KTLH+R+ + + +A+FL SN V V YPGLP+H + +VK+Q
Sbjct: 248 SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQC 307
Query: 298 RDALGGGMISFRIKGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQRE 357
GM++F IKG + ESLGG ESL E+PA+MTH + K R+
Sbjct: 308 TGCT--GMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRD 365
Query: 358 ASGVYDDLVRLSIGIEDTDDLLEDIKQALASA 389
G+ D L+RLS+G+ED +DLLED+ QAL +A
Sbjct: 366 VLGISDTLIRLSVGLEDEEDLLEDLDQALKAA 397
>CE07648 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 392
Score = 342 bits (876), Expect = 7e-94
Identities = 182/385 (47%), Positives = 248/385 (64%), Gaps = 7/385 (1%)
Query: 9 FATKAIHAGTHVDVH--GSVIEPISLSTTFKQSAPAQPIGEYEYSRSQNPNRKNLEDAIA 66
F T AIH G + V+ PISLS+T+KQ P +P G ++YSR+ NP R L+ +A
Sbjct: 7 FGTAAIHVGQEPEQWDMNQVVPPISLSSTYKQDNPGEPKG-HDYSRAGNPTRDVLQKNLA 65
Query: 67 ALENGKYGLAFSSGSATTAVILQSLPQGSHAVSIGDVYGGTHRYFTKVANA-HGVETTFT 125
ALE+ K+ FSSG A T+ I+ L G H V DVYGGT RY +VA HG+E
Sbjct: 66 ALEDAKHCQVFSSGLAATSAIINLLKYGDHIVCSDDVYGGTQRYIRRVAVPNHGLEVDSV 125
Query: 126 NNL-VAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVDNTFLSPY 184
+ V L IK NTK+VW E+P+NP LKV DI V +TAK N +I++VVDNTF+SPY
Sbjct: 126 DLTDVQNLEKAIKPNTKMVWFESPSNPLLKVVDIAAVVQTAKKANPEIVVVVDNTFMSPY 185
Query: 185 LSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIPSPFDSWL 244
P++ GAD+VVHS TKYINGHSDVV+G + T++ + L F+Q A+GA+PSPFD +L
Sbjct: 186 FQRPISLGADVVVHSITKYINGHSDVVMGAVITDNDEFQQHLFFMQLAVGAVPSPFDCFL 245
Query: 245 VHRGVKTLHLRVRQASLSAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQHRDALGGG 304
V+RG+KTLH+R+R +A +A++L +N+ + +V YP LP+H + V +KQ + G
Sbjct: 246 VNRGLKTLHIRMRAHYENALAVAKYLEANDRIESVLYPALPSHPQHEVHEKQTKGM--SG 303
Query: 305 MISFRIKGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQREASGVYDD 364
MISF +KG + ESLGG ESL E+P++MTH +P E R G+ D+
Sbjct: 304 MISFYLKGELQESRAFLSALKVFTLAESLGGYESLAELPSIMTHASVPAETRIVLGITDN 363
Query: 365 LVRLSIGIEDTDDLLEDIKQALASA 389
L+R+S+GIED DDL+ D+ QAL A
Sbjct: 364 LIRISVGIEDLDDLVADLDQALKIA 388
>CE15884 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 392
Score = 329 bits (843), Expect = 5e-90
Identities = 175/385 (45%), Positives = 240/385 (61%), Gaps = 7/385 (1%)
Query: 9 FATKAIHAGTHVDVH--GSVIEPISLSTTFKQSAPAQPIGEYEYSRSQNPNRKNLEDAIA 66
F T A+H G + V+ PIS+STT+KQ P +P Y+Y+R NP R L+ +A
Sbjct: 7 FGTDAVHVGQEPEQWDINQVVPPISMSTTYKQDNPGEP-KRYDYARGGNPTRDVLQKNLA 65
Query: 67 ALENGKYGLAFSSGSATTAVILQSLPQGSHAVSIGDVYGGTHRYFTKVA-NAHGVETTFT 125
ALE K+ AFSSG A ++ ++ L G H V DVYGGT RY ++A +G+E
Sbjct: 66 ALEGAKHCQAFSSGLAASSAVINLLNHGDHIVCSDDVYGGTIRYIRQIAVKKYGMEVDSV 125
Query: 126 NNL-VAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVDNTFLSPY 184
+ V L IK NTK+VW E+P+NP LKV DI V +TAK N +I++VVDNTF++PY
Sbjct: 126 DLTDVQNLEKAIKPNTKMVWFESPSNPLLKVVDIAAVVQTAKRANPEIVVVVDNTFMTPY 185
Query: 185 LSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIPSPFDSWL 244
PL+ GADI VHS TKYINGHSD+++G TN+ + L F+Q AIG +PSPFD +L
Sbjct: 186 FQRPLSLGADIAVHSITKYINGHSDIIMGAAITNNDEFQQHLHFMQRAIGGVPSPFDCFL 245
Query: 245 VHRGVKTLHLRVRQASLSAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQHRDALGGG 304
V+RG+KTLH+R++ +A IA+FL +++ + +V YP LP+H + V KQ + G
Sbjct: 246 VNRGLKTLHVRMKAHFENALAIAKFLEAHDCIESVLYPALPSHPQHTVHVKQTKGM--SG 303
Query: 305 MISFRIKGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQREASGVYDD 364
MISF +KG ESLGG ESL E+P++MTH +P R G+ D+
Sbjct: 304 MISFYLKGELCQSRAFLSALKVFTLAESLGGCESLAELPSIMTHASVPSATRAELGITDN 363
Query: 365 LVRLSIGIEDTDDLLEDIKQALASA 389
L+R+S+GIED DDL+ D+ QAL A
Sbjct: 364 LIRISVGIEDLDDLIADLDQALKIA 388
>At3g57050 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 464
Score = 253 bits (646), Expect = 3e-67
Identities = 143/374 (38%), Positives = 212/374 (56%), Gaps = 7/374 (1%)
Query: 10 ATKAIHAGTHVDVHGSVIEPISLSTTFKQSAPAQPIGEYEYSRSQNPNRKNLEDAIAALE 69
+T ++ D ++ P+ + TFKQ + + G Y+Y+RS NP R LE +A L+
Sbjct: 88 STLLVNLDNKFDPFDAMSTPLYQTATFKQPSAIEN-GPYDYTRSGNPTRDALESLLAKLD 146
Query: 70 NGKYGLAFSSGSATTAVILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVETTFTNNL- 128
F+SG A + + + G V+ DVYGG+ R ++V GV N
Sbjct: 147 KADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTK 206
Query: 129 VAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVDNTFLSPYLSNP 188
+ E+ + I TKLVW+E+PTNP +++DI +++ A + + L++VDN+ +SP LS P
Sbjct: 207 LDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHA--QGALVLVDNSIMSPVLSRP 264
Query: 189 LNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIPSPFDSWLVHRG 248
L GADIV+HSATK+I GHSDV+ GVLA + + +++ FLQN+ G+ +PFD WL RG
Sbjct: 265 LELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRG 324
Query: 249 VKTLHLRVRQASLSAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQHRDALGGGMISF 308
+KT+ LR+ + +A KIA +LSS+ V V Y GLP H + + Q A G G +
Sbjct: 325 IKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQ---AKGAGSVFS 381
Query: 309 RIKGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQREASGVYDDLVRL 368
I G S G ++SL+ +P M+H IP E REA G+ +DLVR+
Sbjct: 382 FITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRI 441
Query: 369 SIGIEDTDDLLEDI 382
S GIED DDL+ D+
Sbjct: 442 SAGIEDVDDLISDL 455
>At3g01120 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 563
Score = 218 bits (555), Expect = 1e-56
Identities = 138/386 (35%), Positives = 213/386 (54%), Gaps = 18/386 (4%)
Query: 14 IHAGTHVD---VHGSVIEPISLSTT--FKQSAPAQPIGE-----YEYSRSQNPNRKNLED 63
+HAG + V ++ P+ ++ FK++A E +EY R NP LED
Sbjct: 180 VHAGERLGRGIVTDAITTPVVNTSAYFFKKTAELIDFKEKRSVSFEYGRYGNPTTVVLED 239
Query: 64 AIAALENGKYGLAFSSGS-ATTAVILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVET 122
I+ALE + L +SG A+T ++L +P G H V+ D Y T + G+
Sbjct: 240 KISALEGAESTLVMASGMCASTVMLLALVPAGGHIVTTTDCYRKTRIFMENFLPKLGITV 299
Query: 123 TFTNNL-VAELPSLIKE-NTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVDNTF 180
T + +A L + + E L + E+PTNP L+ DIELV+K + L+ +D TF
Sbjct: 300 TVIDPADIAGLEAAVNEFKVSLFFTESPTNPFLRCVDIELVSKICHK--RGTLVCIDGTF 357
Query: 181 LSPYLSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIPSPF 240
+P L GAD+VVHSATKYI GH+DV+ G + + K++ E ++ L + +G +P
Sbjct: 358 ATPLNQKALALGADLVVHSATKYIGGHNDVLAGCICGSLKLVSE-IRNLHHVLGGTLNPN 416
Query: 241 DSWLVHRGVKTLHLRVRQASLSAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQHRDA 300
++L+ RG+KTLHLRV+Q + +A ++AE L ++ V V YPGLP+H + + K+Q
Sbjct: 417 AAYLIIRGMKTLHLRVQQQNSTAFRMAEILEAHPKVSHVYYPGLPSHPEHELAKRQMTGF 476
Query: 301 LGGGMISFRIKGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQREASG 360
GG++SF I G E S GG ES+++ PA+M++ +P+E+R G
Sbjct: 477 --GGVVSFEIDGDIETTIKFVDSLKIPYIAPSFGGCESIVDQPAIMSYWDLPQEERLKYG 534
Query: 361 VYDDLVRLSIGIEDTDDLLEDIKQAL 386
+ D+LVR S G+ED +D+ DI QAL
Sbjct: 535 IKDNLVRFSFGVEDFEDVKADILQAL 560
>CE17400 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 444
Score = 201 bits (512), Expect = 1e-51
Identities = 133/372 (35%), Positives = 196/372 (51%), Gaps = 23/372 (6%)
Query: 26 VIEPISLSTTFKQSAPAQ-----PIGEYEYSRSQNPNRKNLEDAIAALENGKYGLAFSSG 80
V+ PI S+T++ Q + Y R NP +N+E I +E G L ++SG
Sbjct: 82 VVVPIYHSSTYRFKTVDQFNEDNHGANFVYRRCGNPTTENVEVVINEIEGGAGSLLYNSG 141
Query: 81 -SATTAVILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVETTFTN-----NLVAELPS 134
+A +AV L+ L G+H + + +Y GT + + GVE T + + +
Sbjct: 142 LAAISAVFLEFLSSGAHMIVMNPIYSGTSSFINETLARFGVEITSVDVEKEKDFAGAVEK 201
Query: 135 LIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVDNTFLSPYLSNPLNFGAD 194
I+ NTK+++ E+ NPT+ V DI + AK IL +D TF SPY PL GAD
Sbjct: 202 AIRPNTKMIYFESIANPTMAVPDILGTIEVAKKYK--ILTCLDATFSSPYNIQPLKLGAD 259
Query: 195 IVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIPSPFDSWLVHRGVKTLHL 254
I +HS +KYI GH+DV+ GV+ + ++KL+ Q G+ SP+D+ L+ RG+KTL L
Sbjct: 260 ISLHSCSKYIGGHTDVIAGVVTVSSYDNWKKLKLQQLTTGSSLSPYDAALLTRGLKTLGL 319
Query: 255 RVRQASLSAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQHRDALGGGMISFRIKGGA 314
RV + S +A K AEFL S+ V V YPGLP+H + K+ + GMI+F + G A
Sbjct: 320 RVDRISENAQKTAEFLESHPKVERVFYPGLPSHPQHQYAKQVMKQF--AGMIAFDV-GTA 376
Query: 315 EXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQREASGVYDDLVRLSIGIED 374
E SLGG ESL+E P M+HG + V L+R S+GIE+
Sbjct: 377 ENAIKLVEAI-------SLGGTESLIEHPLSMSHGKHLLRYLDGPTVAPGLLRFSVGIEN 429
Query: 375 TDDLLEDIKQAL 386
+D++ D+ AL
Sbjct: 430 VEDIIGDLNDAL 441
>At1g33320 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 412
Score = 189 bits (479), Expect = 8e-48
Identities = 120/342 (35%), Positives = 185/342 (54%), Gaps = 9/342 (2%)
Query: 48 YEYSRSQNPNRKNLEDAIAALENGKYGLAFSSGS-ATTAVILQSLPQGSHAVSIGDVYGG 106
YEY+R NP LE+ I+ LE + L +SG A+ ++L +P H V+ D Y
Sbjct: 74 YEYARYGNPTTMALEEKISVLEGAESTLVMASGMYASNVMLLALVPTNGHIVATKDCYKE 133
Query: 107 THRYFTKVANAHGVETTFTNNL-VAELPSLIKEN-TKLVWIETPTNPTLKVTDIELVAKT 164
T + G+ TF ++ +A L +L+ + L + E+PTNP L+ DI+LV+K
Sbjct: 134 TRIFMENFLTKLGITVTFIDSDDIAGLQTLVNNHEVSLFFTESPTNPFLRCVDIKLVSKI 193
Query: 165 AKSINKDILLVVDNTFLSPYLSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYE 224
+ L+ +D T +P L GAD+V HSATKYI GH+D + G ++ + +++
Sbjct: 194 CH--RRGTLVCIDATIATPINQKTLALGADLVHHSATKYIGGHNDFLAGSISGSMELV-S 250
Query: 225 KLQFLQNAIGAIPSPFDSWLVHRGVKTLHLRVRQASLSAHKIAEFLSSNENVIAVNYPGL 284
K++ L +G +P ++L+ RG+KT+HLRVRQ + + K+A+ L ++ V V Y GL
Sbjct: 251 KIRNLHKLLGGTLNPNAAYLLIRGMKTMHLRVRQQNSTGMKMAQVLEAHPKVSRVYYLGL 310
Query: 285 PTHESYAVVKKQHRDALGGGMISFRIKGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPA 344
P+H + + K+Q GG+ISF I G + S GG ESL++ A
Sbjct: 311 PSHPEHLIAKRQMTGI--GGLISFEIDGDLKTTIKFIDALKIPYLAASFGGCESLVDQLA 368
Query: 345 VMTHGGIPKEQREASGVYDDLVRLSIGIEDTDDLLEDIKQAL 386
IP+E+R G D+LVR S GIED +D+ D+ QAL
Sbjct: 369 TGI-WDIPREERLKDGFQDNLVRFSFGIEDFEDIKADVLQAL 409
>YGL184c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 465
Score = 182 bits (463), Expect = 6e-46
Identities = 139/412 (33%), Positives = 203/412 (48%), Gaps = 31/412 (7%)
Query: 4 LPTDKFATKAIHAGTHVDVHGSVIEPISLSTTFKQSAPAQPIGEYEYSRSQNPNRKNLED 63
+P + T ++ G+ D H + + P+ LSTTFK + Y+YSRS NP R L+
Sbjct: 1 MPIKRLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
Query: 64 AIAALEN--GKYGLAFSSGSATTAVILQSLP----QGSHAVSI---GDVYGGTHR---YF 111
I L + LA SSG VIL+ L +H +I D+YGGT R +F
Sbjct: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
Query: 112 TKVANAHGV--ETTFTNNLVAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSIN 169
+ ++A V +T+ SL K + L +E+PTNP KV DI + + K I+
Sbjct: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVL--LESPTNPLCKVVDIPRILRFVKCIS 178
Query: 170 KDILLVVDNTFLSPYLSNPL--NFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQ 227
D +VVDNT +S NPL N G D+V SATKY+NGH D++ GV+ + I KL
Sbjct: 179 PDTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLY 238
Query: 228 FLQNAIGAIPSPFDSWLVHRGVKTLHLRVRQASLSAHKIAEFLSSN--------ENVIAV 279
F+ N+ GA SP DSWL+ RG+KTL +R+ Q +A +A +L ++
Sbjct: 239 FVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKT 298
Query: 280 NYPGLPTHESYAVVKKQHRDALGGGMISFRIKGGAEXXXXXXXXXXXX--XXXESLGGIE 337
+ GL ++ + + K + G ++SF G E S G +
Sbjct: 299 RFVGLRSNPDFKLHKSFNNGP--GAVLSFE-TGSFEHSKRLVSSKKLSIWAVTVSFGCVN 355
Query: 338 SLLEVPAVMTHGGIPKEQREASGVYDDLVRLSIGIEDTDDLLEDIKQALASA 389
SLL +P M+H I E R+ +DLVRL GIE+ DL +D+ A+ A
Sbjct: 356 SLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
>SPBC428.11 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 429
Score = 182 bits (461), Expect = 1e-45
Identities = 136/430 (31%), Positives = 214/430 (49%), Gaps = 51/430 (11%)
Query: 6 TDKFATKAIHAGTHVDVH-GSVIEPISLSTTFK--------QSAPAQPIGEYEYSRSQNP 56
++ F T +HAG D S PI +T++ + Q G Y YSR NP
Sbjct: 5 SEHFETLQLHAGQEPDAATSSRAVPIYATTSYVFRDCDHGGRLFGLQEPG-YIYSRMMNP 63
Query: 57 NRKNLEDAIAALENGKYGLAFSSGSATTAVILQSLPQ-GSHAVSIGDVYGGTHRYFTKVA 115
E IAALE+G +A SSG++ + L +L + G + VS +YGGT+ F
Sbjct: 64 TADVFEKRIAALEHGAAAIATSSGTSALFMALTTLAKAGDNIVSTSYLYGGTYNLFKVTL 123
Query: 116 NAHGVETTFTN-NLVAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILL 174
G+ T F N + +L + I ENTK V++E+ NP V D E +A+ A + + L
Sbjct: 124 PRLGITTKFVNGDDPNDLAAQIDENTKAVYVESIGNPMYNVPDFERIAEVAHAAG--VPL 181
Query: 175 VVDNTFLSP-YLSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEK-------- 225
+VDNTF YL P++ GADIV HSATK+I GH + GV+ + K ++K
Sbjct: 182 MVDNTFGGGGYLVRPIDHGADIVTHSATKWIGGHGTTIGGVIVDSGKFDWKKNSKRFPEF 241
Query: 226 --------------------------LQFLQNAIGAIPSPFDSWLVHRGVKTLHLRVRQA 259
Q L++ +G +PF +L+ +G++TL LR+ +
Sbjct: 242 NEPHPGYHGMVFTETFGNLAYAFACRTQTLRD-VGGNANPFGVFLLLQGLETLSLRMERH 300
Query: 260 SLSAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQHRDALGGGMISFRIKGGAEXXXX 319
+A +A++L + V V+YPGL +H S+ + KK ++ G ++SF KGG +
Sbjct: 301 VQNAFALAKYLEKHPKVNWVSYPGLESHVSHKLAKKYLKNGY-GAVLSFGAKGGPDQSRK 359
Query: 320 XXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQREASGVYDDLVRLSIGIEDTDDLL 379
++G ++L+ PA TH + E++ ++GV DL+R+++GIE DD++
Sbjct: 360 VVNALKLASQLANVGDAKTLVIAPAYTTHLQLTDEEQISAGVTKDLIRVAVGIEHIDDII 419
Query: 380 EDIKQALASA 389
D QAL A
Sbjct: 420 ADFAQALEVA 429
>YLR303w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 444
Score = 174 bits (440), Expect = 3e-43
Identities = 135/438 (30%), Positives = 205/438 (45%), Gaps = 69/438 (15%)
Query: 9 FATKAIHAGTHV---DVHGSVIEPISLSTTF---KQSAPAQPIG----EYEYSRSQNPNR 58
F T +HAG + H S PI +T++ +Q G Y YSR QNP
Sbjct: 5 FDTVQLHAGQENPGDNAHRSRAVPIYATTSYVFENSKHGSQLFGLEVPGYVYSRFQNPTS 64
Query: 59 KNLEDAIAALENGKYGLAFSSGSATTAVILQSLPQ-GSHAVSIGDVYGGTHRYFTKVANA 117
LE+ IAALE G LA SSG A + +Q L G + VS +YGGT+ F
Sbjct: 65 NVLEERIAALEGGAAALAVSSGQAAQTLAIQGLAHTGDNIVSTSYLYGGTYNQFKISFKR 124
Query: 118 HGVETTFT-NNLVAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVV 176
G+E F + E + E TK V++ET NP V D E + A I +VV
Sbjct: 125 FGIEARFVEGDNPEEFEKVFDERTKAVYLETIGNPKYNVPDFEKIVAIAH--KHGIPVVV 182
Query: 177 DNTF-LSPYLSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDK--------------- 220
DNTF Y P+ +GADIV HSATK+I GH + G++ + K
Sbjct: 183 DNTFGAGGYFCQPIKYGADIVTHSATKWIGGHGTTIGGIIVDSGKFPWKDYPEKFPQFSQ 242
Query: 221 -------------------VIYEKLQFLQNAIGAIPSPFDSWLVHRGVKTLHLRVRQASL 261
+++ + + L++ +G + +PF S+L+ +GV+TL LR +
Sbjct: 243 PAEGYHGTIYNEAYGNLAYIVHVRTELLRD-LGPLMNPFASFLLLQGVETLSLRAERHGE 301
Query: 262 SAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQHRDALGGGMISFRIK---------- 311
+A K+A++L + V V+YPGL +H + KK + GG++SF +K
Sbjct: 302 NALKLAKWLEQSPYVSWVSYPGLASHSHHENAKKYLSNGF-GGVLSFGVKDLPNADKETD 360
Query: 312 ----GGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQREASGVYDDLVR 367
GA+ ++G ++L+ P TH + +++ ASGV DL+R
Sbjct: 361 PFKLSGAQVVDNLKLASNLA----NVGDAKTLVIAPYFTTHKQLNDKEKLASGVTKDLIR 416
Query: 368 LSIGIEDTDDLLEDIKQA 385
+S+GIE DD++ D +Q+
Sbjct: 417 VSVGIEFIDDIIADFQQS 434
>At1g64660 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 441
Score = 137 bits (344), Expect = 4e-32
Identities = 109/377 (28%), Positives = 187/377 (48%), Gaps = 23/377 (6%)
Query: 15 HAGTHVDVHGS----VIEPISLSTTFK-QSAPAQPIGEYEYSRSQNPNRKNLEDAIAALE 69
H G ++ + S V+EP ++ F + P Y YSR NP NL +AALE
Sbjct: 57 HGGVNMSIEASATFTVMEPDTMRRMFTGELGPDNDF--YVYSRHFNPTVLNLSRQMAALE 114
Query: 70 NGKYGLAFSSG-SATTAVILQSLPQGSHAVSIGDVYGGTHRYFTK-VANAHGVETTFTN- 126
+ SSG SA ++V+LQ G H V+ +YGGTH + + + T+F +
Sbjct: 115 GTQAAYCTSSGMSAISSVMLQLCSSGGHVVAASTLYGGTHALLSHFLPRTCNITTSFVDI 174
Query: 127 -NLVAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVDNTFLSPYL 185
+ A ++++ T++++ E+ NPTL V DI +++ A K + +VVDNTF +P +
Sbjct: 175 TDHGAVANAIVEGRTQVLYFESVANPTLTVADIPELSRMAHE--KGVTVVVDNTF-APMV 231
Query: 186 SNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNA---IGAIPSPFDS 242
+P GAD+VVHS +K+I+G +D++ G + ++ ++ E + + +G + +
Sbjct: 232 LSPAKLGADVVVHSISKFISGGADIIAGAVCGSENLVKEMMDLRGGSLMLLGPTMNAKVA 291
Query: 243 WLVHRGVKTLHLRVRQASLSAHKIAEFLSSNENVIAVNYPGLPTHESYAVVKKQ-HRDAL 301
+ + + L LR+R+ S A AE + + + V YPGL TH + + K +RD
Sbjct: 292 FELSERIPHLGLRMREHSHRAQVYAERM--RDLGMKVIYPGLETHPQHKLFKGMVNRDYG 349
Query: 302 GGGMISFRI---KGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIPKEQREA 358
GG++S + + + SLG E+L+ T + Q+EA
Sbjct: 350 YGGLLSIDMETEEKANKLMAYLQNATQFGFMAVSLGYYETLMSCSGSSTSSELDPSQKEA 409
Query: 359 SGVYDDLVRLSIGIEDT 375
+G+ LVR+S+G T
Sbjct: 410 AGISPGLVRMSVGYVGT 426
>YHR112c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 378
Score = 128 bits (321), Expect = 2e-29
Identities = 119/394 (30%), Positives = 187/394 (47%), Gaps = 44/394 (11%)
Query: 10 ATKAIHAGTHVDVHGSVIEPISLSTTFK-QSAPAQPIGEYE----------YSRSQNPNR 58
+T IH + V PI++STTF+ P E E YSR +PN
Sbjct: 5 STALIHGDDKDNRVTDVAPPINVSTTFRYDDDDLIPWTERENLDFMEKKPVYSRLAHPNS 64
Query: 59 KNLEDAIAALENGKYGLAFSSGSATTAVILQSLPQGSHAVSIGDVYGGTHRYFTKVANAH 118
LE + + +G Y + +SSG A A + + IG Y G + +
Sbjct: 65 TRLESIFSEILDG-YAVIYSSGLA--AFYAAMVHYNPKKIFIGQSYHGVRAIANILTRNY 121
Query: 119 GVETTFTNNLVAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVDN 178
G+E + + ++ E +V +E+P NP +DIE +A+ A + K LL+VD+
Sbjct: 122 GIE----QHPLEDIEKCASEGD-IVHLESPVNPYGTSSDIESLARRAHA--KGALLIVDS 174
Query: 179 TFLSPYLSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIPS 238
TF SP L NFGADIV++SATKY GHSD++ GVL ++ +L+ + +G +
Sbjct: 175 TFASPPLQYAWNFGADIVLYSATKYFGGHSDLLSGVLVVKEEATSRQLKDDRIYLGTNVA 234
Query: 239 PFDSWLVHRGVKTLHLRVRQASLSAHKIAEFLSSNEN-----VIAVNYPGLPTHESYAVV 293
+S+++ R ++T +R+ + S +A K+ FLS +++ + + + L T E V
Sbjct: 235 NLESFMLLRSLRTYEMRITKQSENATKLVRFLSDHQSEFDKVLKTIYHSSLQTEE---FV 291
Query: 294 KKQHRDALGG-GMISFRIKGGAEXXXXXXXXXXXXXXXESLGGIESLLEVPAVMTHGGIP 352
KKQ +GG G + E SLGGIESL+E A MT I
Sbjct: 292 KKQ---LVGGYGPVFAITLYTKEQCKQLPLKLKYFHHATSLGGIESLVEWRA-MTDPYID 347
Query: 353 KEQREASGVYDDLVRLSIGIEDTDDLLEDIKQAL 386
+ L+R+S+G E +DL++D+ AL
Sbjct: 348 Q----------TLIRVSVGCESANDLIKDLASAL 371
>SPAC23A1.14c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 398
Score = 124 bits (312), Expect = 2e-28
Identities = 114/407 (28%), Positives = 179/407 (43%), Gaps = 51/407 (12%)
Query: 10 ATKAIHAGTHVDVHGSVIEPISLSTTFKQSA------PAQPIGEYEYSRSQNPNRKNLED 63
+T +HA + V PI +STT+ P + E ++ + N++
Sbjct: 17 STNVLHADDAYALENDVAPPIHISTTYTYPGTPDTLQPFTKLAEEDFPYYARISGNNVDR 76
Query: 64 AIAALEN--GKYGLAFSSGSATTAVILQSLPQ---GSHAVSIGDVYGGTHRYFTKVANAH 118
A A+L + G + +SSG A +L L H G Y GT + ++
Sbjct: 77 AEASLSSVLGAPSVVYSSGLAAIYGLLSYLNPKHIAVHKPGFGG-YSGTIQIIARINRLT 135
Query: 119 GVETTFTNNLVAELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKSINKDILLVVDN 178
G+ET+F + + ++W+ETP NP DI + AK K +LVVD+
Sbjct: 136 GLETSFIDGKCDAIGE-----GDVIWLETPLNPLGIAFDIPFYKELAKK--KGAILVVDS 188
Query: 179 TFLSPYLSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQFLQNAIGAIPS 238
TF P + + L GAD VVHSATKY+ GHSDV+ GV A+ D+ L+ + +G I
Sbjct: 189 TFAPPPIQDALVLGADYVVHSATKYLAGHSDVLAGVTASKDRSKILDLKADRAYLGTILH 248
Query: 239 PFDSWLVHRGVKTLHLRVRQASLSAHKIAEFLS--------------SNENVIAVNYPGL 284
P ++L+ R ++T LR+ + S + +A+ L+ + ++ V + L
Sbjct: 249 PQQAFLLLRSLRTFPLRIAKHSENGFLVAQHLNKLATDEQFATSLGIDSSLILEVYHNSL 308
Query: 285 PTHESYAVVKKQHRDALGGGMISFRIKGGAEXXXXXX-XXXXXXXXXESLGGIESLLEVP 343
T E A ++ GG F + ++ SLG +ESL+E
Sbjct: 309 QTKEFVA------KNLTGGHASCFSVLLKSDTVAKHLCCELKYFHHATSLGSVESLIE-- 360
Query: 344 AVMTHGGIPKEQREASGVYDDLVRLSIGIEDTDDLLEDIKQALASAS 390
+ S + LVRLSIGIED DL+ D+ + AS S
Sbjct: 361 ---------WRRMTDSKIDPRLVRLSIGIEDAADLIADLNRVFASLS 398
>YFR055w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 340
Score = 113 bits (283), Expect = 4e-25
Identities = 79/270 (29%), Positives = 138/270 (50%), Gaps = 15/270 (5%)
Query: 50 YSRSQNPNRKNLEDAIAALENGKYGLAFSSGSATTAVILQSLPQ-GSHAVSIGDVYGGTH 108
Y + +P NLE+A L G + +SG + ++ L +L + G H + VY T
Sbjct: 56 YGTAGSPTIDNLENAWTHLTGGAGTVLSASGLGSISLALLALSKAGDHILMTDSVYVPTR 115
Query: 109 RYFTKVANAHGVETTFTNNLVA-ELPSLIKENTKLVWIETPTNPTLKVTDIELVAKTAKS 167
+ GVET + + + ++ L+K NT ++++E+P + T++V DI + AK
Sbjct: 116 MLCDGLLAKFGVETDYYDPSIGKDIEKLVKPNTTVIFLESPGSGTMEVQDIPALVSVAKK 175
Query: 168 INKDILLVVDNTFLSPYLSNPLNFGADIVVHSATKYINGHSDVVLGVLATNDKVIYEKLQ 227
I ++DNT+ +P + G DI V + TKY+ GHSD+++G+ + N++ + L+
Sbjct: 176 --HGIKTILDNTWATPLFFDAHAHGIDISVEAGTKYLGGHSDLLIGLASANEE-CWPLLR 232
Query: 228 FLQNAIGAIPSPFDSWLVHRGVKTLHLRVRQASLSAHKIAEFLSSNENVIAVNYPGL--- 284
+A+ +P D L RG++TLHLR+++ A +A +L + + V V +P
Sbjct: 233 STYDAMAMLPGAEDCQLALRGMRTLHLRLKEVERKALDLAAWLGNRDEVEKVLHPAFEDC 292
Query: 285 PTHESYAVVKKQHRDALG-GGMISFRIKGG 313
P HE + RD G G+ S +K G
Sbjct: 293 PGHEYWV------RDYKGSSGLFSIVLKNG 316
>SPCC11E10.01 [E] KOG0053 Cystathionine beta-lyases/cystathionine
gamma-synthases
Length = 101
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Query: 11 TKAIHAGTHVDVHGSVIEPISLSTTFKQSAPAQPIGEYEYSRSQNPNRKNLEDAIAALEN 70
T+ +H + D + + PI S TFKQ + +G+++Y+RS NP R L+ +A L
Sbjct: 11 TELVHVEGNEDQYHASSVPIYQSATFKQPC-LEHMGKFDYTRSGNPTRSVLQVHLAKLMK 69
Query: 71 GKYGLAFSSGSATTAVILQSLPQGSHAVS 99
K+ S+G + +IL+ SH V+
Sbjct: 70 AKHAFVTSNGMSALDMILRCCKSNSHVVA 98
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.132 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,112,588
Number of Sequences: 60738
Number of extensions: 896863
Number of successful extensions: 1915
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1833
Number of HSP's gapped (non-prelim): 21
length of query: 391
length of database: 30,389,216
effective HSP length: 108
effective length of query: 283
effective length of database: 23,829,512
effective search space: 6743751896
effective search space used: 6743751896
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)