ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2141 good U KOG0412 Intracellular trafficking, secretion, and vesicular transport Golgi transport complex COD1 protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2141 765209 767509 767
(767 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR105c [U] KOG0412 Golgi transport complex COD1 protein 490 e-138
SPCC338.13 [U] KOG0412 Golgi transport complex COD1 protein 131 4e-30
Hs21070956 [U] KOG0412 Golgi transport complex COD1 protein 94 8e-19
>YPR105c [U] KOG0412 Golgi transport complex COD1 protein
Length = 861
Score = 490 bits (1262), Expect = e-138
Identities = 288/848 (33%), Positives = 468/848 (54%), Gaps = 86/848 (10%)
Query: 3 IDEFQLDSKLSKFENLSGKLSTKSQLPKLLHLIEADYSQTSNALNNYIKGSNNKINKSVR 62
I E QL L+++ L KLST SQ+ KL +I DY++ S LN +++ S + +NK R
Sbjct: 14 IIEGQLSKNLARYTLLLDKLSTLSQIDKLSEVIANDYAKQSKQLNAFVQQSQSSLNKESR 73
Query: 63 SLELGKTNLTSTLSFFHEALEXXXXXXXXXXXXXXRLNSIKDEADHINQLADFVDSVKLL 122
LEL +TNLT+TL+ FHE + + ++ E +N+ FV V+ L
Sbjct: 74 KLELQRTNLTTTLTQFHETVATISSSNARAKAIHDDIETVDQERALVNKTLQFVKDVRTL 133
Query: 123 KNNLKIINDALDTKEPNYPMIAQCIYEIDQLPDS-IIHSQFVQRCVPTSELPDPPVQLID 181
KNN+ + + AL+TK+ Y + A I EI LPD +I S+F ++ VP+SE+P+ P LI
Sbjct: 134 KNNISLAHSALETKD--YLVAATAINEIRSLPDKKLIVSEFAKKVVPSSEIPEEPAILIK 191
Query: 182 KWKTHLCKVFSDRFTRATRDVDVGTLTECFKLFPKIGASDLGIDLYSKYICDNIAQQSRT 241
W L +F ++F ATR D+ LT FK+FP IG LG+DLYSKY+CD IA +SR
Sbjct: 192 NWCKELTSLFQEQFMEATRTQDIKELTLMFKMFPMIGQDVLGLDLYSKYVCDIIADESRK 251
Query: 242 LMTHTSGDPL----FYSKSTLHLFKIVSTMINDHSKIILQSYSTDFMLEIMQKVQLETDL 297
+M+++ + F+S+ LHLFKIVST+INDHSK+I Y M+ +M+KV+ E DL
Sbjct: 252 IMSNSMENSTKFQGFFSQVLLHLFKIVSTIINDHSKVIATCYGKKHMVHVMEKVEKEADL 311
Query: 298 QACLIWDTF---------------------TDDVSLDKVFASLQDNND--------MRTL 328
QA LI D F +DV++D + ++ + + + L
Sbjct: 312 QASLILDIFMETRKIERTIHDINEWEHSQKNEDVNIDSNQSDIETDGETEKSSIISIHDL 371
Query: 329 QAIILQFSNFLQNWSMYCQFFSMKWLQFTNGSVDPIKIVPCLTSGKFNSKL-QDNI-DTF 386
+I++FS LQNWSMY +F+S+KW +F++ ++ P + GKF KL QD + D F
Sbjct: 372 ALLIMEFSQILQNWSMYSRFYSVKWNEFSDLHPHVLQPPPPIADGKFALKLKQDKVFDEF 431
Query: 387 HALTIHYTTYCFKSSLKTSCMPNLNDSLDITLSQNTESNQQIISPVLEDLAILIKSYLVW 446
+++ F++S+ +P+LND + + ++ ++ VL+DL +L++ L+
Sbjct: 432 QVFVLNHLQRSFRNSISLEELPSLNDLITAVPLNDHDNISYPVTSVLDDLILLVRKNLIS 491
Query: 447 TLNSGQTELVTKSLDSISQMIQNEYLISFVQSSLTKLIPRLTPALRLQKYI--------- 497
+N+GQ +L+ L+ + + QN +L+ F+Q+ L +L + L++YI
Sbjct: 492 VVNTGQFKLLASFLNELVKFFQNRFLVKFMQNKFKLLQSKLASNVSLKRYIPKGEEQSAT 551
Query: 498 ----SAPNYPMDTQSKFTSQFAAF--------NLKET---DMESVLHLHHYIVYLNTIST 542
S P S+FT + AA NL+ D +S+L LHHY++YLNT+
Sbjct: 552 SRSVSPPANKFSPLSRFTFRGAAASALTNIQSNLQAVVAEDEDSILALHHYLIYLNTLYL 611
Query: 543 NESIFKDLFENEIIKINPHFLI-DNFKFNNEHELVKGKLLSVLQYILDNNKKLWNWAIMM 601
++ L EI++ + ++ DNF F+N+ ++ +++ + +L+ KL WA+
Sbjct: 612 SKVYVHRLLSIEILEDDSQRILRDNFPFDNDAAQLQNLIINSEKLVLEQTDKLSKWAVKY 671
Query: 602 LYQNVLQENLHRLLSVLF------------QRNTE-----------FLSTLQDFEDFEKL 638
L+QN+LQ + LL +F Q+N ++++++DFED ++
Sbjct: 672 LFQNILQNRVRNLLGTVFVNSASSNSSTSNQKNVSRDYSAGSNQKNYITSIEDFEDLSQI 731
Query: 639 HKFVEEWNKLLTPYKQVLSAASFNNLLTTIVKDVCPIIENKFLSLQFNELGSIKIEKQLS 698
+ F +WN+L+ PYK +L ++ LL+ IV + +E + +L+FNELG K++++LS
Sbjct: 732 NSFNSKWNQLIIPYKNILHNEAYAELLSVIVDYIVTTLEQRIWTLEFNELGVTKLDRELS 791
Query: 699 IVIKTISMDNYQLREWFKKLTQMCLLLGFEDDQFDSSTQDLKDDVLNSLNWLLTSSERIS 758
+ I + NY LRE F KLTQ+ LLLG +DD FD +T D+KDD + +W++ S ERI
Sbjct: 792 LFIGNMCGLNYNLREKFLKLTQIVLLLGLDDDNFDLTTGDIKDDFNGTFDWVINSQERIK 851
Query: 759 IRQQRIDK 766
R +ID+
Sbjct: 852 ARNMKIDR 859
>SPCC338.13 [U] KOG0412 Golgi transport complex COD1 protein
Length = 738
Score = 131 bits (329), Expect = 4e-30
Identities = 157/777 (20%), Positives = 316/777 (40%), Gaps = 107/777 (13%)
Query: 26 SQLPKLLHLIEADYSQTSNALNNYIKGSN--NKINKSVRSLELGKTNLTSTLSFFHEALE 83
SQ+ + H ++ + +T L + + K N ++++ L + E +
Sbjct: 12 SQIKQRFHDLQVESQRTDEKLERLLSDAQPTEKFNSLIKNMA---ERLVLFVGQIEELKD 68
Query: 84 XXXXXXXXXXXXXXRLNSIKDEADHINQLADFVDSVKLLKNNLKIINDALDTKEPNYPMI 143
R+ S+ E + I + FV V+ K L+ +N A+ ++ +
Sbjct: 69 AFCNTTIVSEEVIERIKSVDREQNRIKECLLFVRQVRDFKECLQDLNRAMHHQQ--WEKA 126
Query: 144 AQCIYEIDQLPDSIIHSQFVQRCVPTSELPDPPVQLIDKWKTHLCKVFSDRFTRATRDVD 203
A ++ +II +F VPT+E P P+ + + L +F F +A R+ D
Sbjct: 127 ADLVHRASSTSPAIIEGKFAHAVVPTAEQPLAPMDTLKEITESLHTLFWREFHKAARNQD 186
Query: 204 VGTLTECFKLFPKIGASDLGIDLYSKYICDNIAQQSRTLMTHTSGDPLFYSKSTLHLFKI 263
+T FKLFP IG G++ Y + IA ++R + LF++++ L +
Sbjct: 187 QKEITRYFKLFPLIGKEKEGLEAYWHFFGGIIASKARATLDEPPTHALFFAQAFTGLVEH 246
Query: 264 VSTMINDHSKIILQSYSTDFMLEIMQKVQLETDLQACLIWDTFTDDVSLDKVFASLQ--- 320
V+++I H+ ++ + Y + +++K+Q + D Q +I +T D +D + +S+
Sbjct: 247 VASIIRAHTPLVQKYYKAKNTITVIEKLQGDCDRQGSIIVNTMFDVRRIDNLVSSIASYK 306
Query: 321 --------------------DNNDMRTLQAIILQFSNFLQNWSMYCQFFS---MKWLQFT 357
+ ++TL I+ + S + W++ F S ++ Q
Sbjct: 307 YILLHAKLKNRAFVSDQKELERVSLQTLHPILNEMSAIVSKWNISKIFISRLVLRLSQSD 366
Query: 358 NGSVDPIKIVPCLTSGKFNSKLQDNIDTFHAL--TIHYTTYCFKSSLKTSCMPNLNDSLD 415
S DP + + FNS + + L + TY F+ S++TS
Sbjct: 367 GTSNDPSVQDNLICASIFNSSKMELLLKKQLLPSLLQLETYYFRRSIETS---------- 416
Query: 416 ITLSQNTESNQQIISPVLEDLAILIKSYLVWTLNSGQTELVTKSLDSISQMIQNEYLISF 475
+ L + +S +++D+ + K ++ ++ ++S + + F
Sbjct: 417 LELEEYYTKVSPWMSSIVDDVMYVTK------------QVFQRAFFTVSSL----FFTRF 460
Query: 476 VQSSLTKLIPRLTPALRLQKYISAPNYPMDTQSKFTSQFAAFNLKETDMESVLHLHHYIV 535
V S L P LR Y+ + + + +QF LK + + +YI
Sbjct: 461 VNES-------LIPILRNDYYVYLSHNLLTVCNIIKAQFQ--RLKNANSIPAKQVENYIT 511
Query: 536 YLNTISTNESIFKDLFENEIIKINPHFLIDNFKFNNEHELVKGKLLSVLQYILDNNKKLW 595
+N+ S ++ K + + ++ + F F + +LVK + + LQ + N + L
Sbjct: 512 LVNSASLSKQYLKSIVDGVSSRLE-----EVFAFAKDQKLVKKSIDNFLQLTV-NFENLC 565
Query: 596 NWAIMMLYQNVLQENLHRLLSVLFQRNTEFLSTLQDFEDFEK--------LHKFVEEWNK 647
+ M + L + + + F LS +ED+ K + + W++
Sbjct: 566 KTSFNMYFPIFLLPRIEQCIDDSFDGINYVLS----YEDYTKETEHERLVVTRLRSVWDR 621
Query: 648 LL-----TPYKQVLSAASFNNLLTTIVKDVCPIIENKFL-SLQFNELGSIKIEKQLSIVI 701
+L TP Q+ +L + + IEN L +Q+N+ G++ +E +S +I
Sbjct: 622 VLLLEQFTPENQL-------SLRSMACEKAASYIENLILYKIQWNDYGAMALENDISSLI 674
Query: 702 KTISMDNYQLREWFKKLTQMCLLLGFEDDQFDSSTQDLKDDVLNSLNWLLTSSERIS 758
S D LR F++L ++ +LL +E D + ++N LN L S + +S
Sbjct: 675 TIFSNDQANLRHSFERLQEILILLVWESD------STAPEQLINDLNLQLLSIDIVS 725
>Hs21070956 [U] KOG0412 Golgi transport complex COD1 protein
Length = 785
Score = 94.0 bits (232), Expect = 8e-19
Identities = 160/815 (19%), Positives = 319/815 (38%), Gaps = 141/815 (17%)
Query: 2 EIDEFQLDSKLSKFENLSGKLSTKSQLPKLLHLIEADYSQTSNALNNYIKGSNNKINKSV 61
++ E +LD+ L + + K+ T ++ L LIE D Q + + + N ++ V
Sbjct: 54 KVVERELDALLEQQNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAEN-VSSKV 112
Query: 62 RSLELGKTNLTSTLSFFHEALEXXXXXXXXXXXXXXRLNSIKDEADHINQLADFVDSVKL 121
R L+L K L ++A++ AD I L +D V+
Sbjct: 113 RQLDLAKNRL-------YQAIQ---------------------RADDILDLKFCMDGVQT 144
Query: 122 LKNNLKIINDALDTKEPNYPMIAQCIYEIDQLPDSIIHSQFVQRCVPTSELPDPPVQLID 181
+ +Y A I+ L S+I + R + D ++L+
Sbjct: 145 A------------LRSEDYEQAAAHIHRYLCLDKSVIE---LSRQGKGGSMIDANLKLLQ 189
Query: 182 KWKTHLCKVFSDRFTRATRDVDVGTLTECFKLFPKIGASDLGIDLYSKYICDNIAQQSR- 240
+ + L + +++F AT++ D+ + FK+FP +G + G+ +S+Y+C +A ++
Sbjct: 190 EAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRRFSEYLCKQVASKAEE 249
Query: 241 -------TLMTHTSGDPLFYSKSTLHLFKIVSTMINDHSKIILQSYSTDFMLEIMQKVQL 293
T M+ +F TL LF+ ++ ++ H I+ Y + +++ +Q+
Sbjct: 250 NLLMVLGTDMSDRRAAVIFADTLTL-LFEGIARIVEAHQPIVETYYGPGRLYTLIKYLQV 308
Query: 294 ETDLQACLIWDTFTDDVSLDKVFASLQDN---------NDMRTLQAIILQFSNFLQNWSM 344
E D Q + D F + F +Q+N + R L I+ + + +
Sbjct: 309 ECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSEL 368
Query: 345 YCQFFSMK-WLQFTNGSVDPIKIV-----PCLTSGKFNSKLQDNIDTFHALTIHYTTYCF 398
Y +F + F G + V CL N L + L + Y
Sbjct: 369 YLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYF- 427
Query: 399 KSSLKTSCMPNLNDSLDITLSQNTESNQQIISPVLEDLAILIKSYLVWTLNSGQTE---- 454
+ ++++ ++ +T Q+ S +++D+ ++K + L+S +
Sbjct: 428 -----------MRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCA 476
Query: 455 ---LVTKSLDS-ISQMIQNEYLISFVQSSLTKLIPRLTPALRLQKYISAPNYPMDTQSKF 510
L T L+S ++ N+ + F ++ + +T A+ + + Q KF
Sbjct: 477 MINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIM-------HSSLQQGKF 529
Query: 511 TSQFAAFNLKETDMESVLHLHHYIVYLNTI---STNESIFKDLFENEIIKINPHFLIDNF 567
++ ++ TD + ++V LN + S N S K E++ K+ F
Sbjct: 530 DTK----GIESTDEAKM----SFLVTLNNVEVCSENISTLKKTLESDCTKL--------F 573
Query: 568 KFNNEHELVKGKLLSVLQYILDNNKKLWNWAIMMLYQNVLQENLHRLLSVLFQRNTE--- 624
E + K L + A+ ++++LQE L L S + +
Sbjct: 574 SQGIGGEQAQAKFDGCLSDLA---------AVSNKFRDLLQEGLTELNSTAIKPQVQPWI 624
Query: 625 --FLSTL-----QDFEDFEK----LHKFVEEWNKLLTPYKQVLSAASFNNLLTTIVKDVC 673
F S ++F D+E + +F+ + + +K LS +++L + V
Sbjct: 625 NSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVA 684
Query: 674 PIIENKFLSLQFNELGSIKIEKQL-SIVIKTISMDNYQLREWFKKLTQMCLLLGFEDDQF 732
+E L FN LG ++ +K+L S++ ++ + +R+ F +L+QM +L E
Sbjct: 685 VELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLER--- 741
Query: 733 DSSTQDLKDDVLNSLNWLLTSSERISIRQQRIDKR 767
+ D L W LT +E + RID R
Sbjct: 742 VTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFR 776
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.135 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,171,120
Number of Sequences: 60738
Number of extensions: 1817852
Number of successful extensions: 5627
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 5615
Number of HSP's gapped (non-prelim): 5
length of query: 767
length of database: 30,389,216
effective HSP length: 114
effective length of query: 653
effective length of database: 23,465,084
effective search space: 15322699852
effective search space used: 15322699852
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)