ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2173 good J KOG1467 Translation, ribosomal structure and biogenesis Translation initiation factor 2B, delta subunit (eIF-2Bdelta/GCD2)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2173 775125 776930 602
(602 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR083c [J] KOG1467 Translation initiation factor 2B delta subun... 620 e-177
SPAC21E11.06 [J] KOG1467 Translation initiation factor 2B delta ... 274 2e-73
At5g38640 [J] KOG1467 Translation initiation factor 2B delta sub... 257 3e-68
Hs14165262 [J] KOG1467 Translation initiation factor 2B delta su... 237 4e-62
At2g44070 [J] KOG1467 Translation initiation factor 2B delta sub... 236 1e-61
At1g48970 [J] KOG1467 Translation initiation factor 2B delta sub... 224 4e-58
7291571 [J] KOG1467 Translation initiation factor 2B delta subun... 194 4e-49
Hs4503503 [J] KOG1466 Translation initiation factor 2B alpha sub... 77 6e-14
7290350 [J] KOG1465 Translation initiation factor 2B beta subuni... 72 3e-12
CE05586 [J] KOG1467 Translation initiation factor 2B delta subun... 71 4e-12
At3g07300 [J] KOG1465 Translation initiation factor 2B beta subu... 71 5e-12
CE00367 [J] KOG1466 Translation initiation factor 2B alpha subun... 67 8e-11
At1g72340 [J] KOG1466 Translation initiation factor 2B alpha sub... 66 1e-10
YKR026c [J] KOG1466 Translation initiation factor 2B alpha subun... 66 2e-10
Hs7657058 [J] KOG1465 Translation initiation factor 2B beta subu... 64 9e-10
SPCC11E10.07c [J] KOG1466 Translation initiation factor 2B alpha... 62 3e-09
SPAC343.14c [J] KOG1465 Translation initiation factor 2B beta su... 58 5e-08
7301868 [J] KOG1466 Translation initiation factor 2B alpha subun... 57 6e-08
At1g53900_2 [J] KOG1466 Translation initiation factor 2B alpha s... 55 2e-07
At1g53880_2 [J] KOG1466 Translation initiation factor 2B alpha s... 55 2e-07
>YGR083c [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 651
Score = 620 bits (1599), Expect = e-177
Identities = 324/552 (58%), Positives = 401/552 (71%), Gaps = 38/552 (6%)
Query: 89 KHDTKKSTLFGHLETAEERRASLLAVSSAITSTGTSRITANGLVLPLLA----------- 137
+ + KKSTLFGHLET EERRA++LA++SA++S TSRITA GL++P++A
Sbjct: 100 ERNVKKSTLFGHLETTEERRATILALTSAVSSPKTSRITAAGLMVPVVASALSGSNVLTA 159
Query: 138 ----------------------TTPAVAVSQPMXXXXXXXXXXXXXXXXXXXAHSEDFEA 175
TT A S + A S +
Sbjct: 160 SSLMPVGPNASSTVSASAPASTTTTLPASSAALSAGTSSASTNTPTAIQQEIASSNASDV 219
Query: 176 HQMLNSLSLDESS-SFVPGISSVIPNTMTSQFTNQQSIASVKELIANREMLHPAITSLTL 234
+ L S+SL+ + +PGISSVIP + F N I+SVKEL+ N++++HP+I LT
Sbjct: 220 AKTLASISLEAGEFNVIPGISSVIPTVLEQSFDNSSLISSVKELLLNKDLIHPSILLLTS 279
Query: 235 DYAFYKIIGSIPRCIAMLEAFQLVVRDYKTPEGTTLSRNLTSYLSHQIDFLKKSRPLSVT 294
A YKI+GSIPRCIAMLE FQ+V++DY+TP+GTTLSRNLTSYLSHQID LKK+RPLSVT
Sbjct: 280 HLAHYKIVGSIPRCIAMLEVFQIVIKDYQTPKGTTLSRNLTSYLSHQIDLLKKARPLSVT 339
Query: 295 MGNAIRWLKQEISLIDPSTPDSKAKKELCDKIAQFARERVQLADQLIIETASQHIEEGST 354
MGNAIRWLKQEISLIDPSTPD AKK+LC+KI QFA+E+++LADQLII+ AS IEE +T
Sbjct: 340 MGNAIRWLKQEISLIDPSTPDKAAKKDLCEKIGQFAKEKIELADQLIIDNASTQIEESTT 399
Query: 355 ILTYGCSKVLTDLFLHNAINFGKNFQIVIVDSRPLFEGRKMAESLRNQGLNVLYVPITAL 414
I+TYG SKVLT+L LHNAI+ KN ++++VDSRPLFEGRKMAE+LRN G+NV+Y IT+L
Sbjct: 400 IVTYGSSKVLTELLLHNAISLKKNIKVIVVDSRPLFEGRKMAETLRNAGVNVMYALITSL 459
Query: 415 GTVFNMDIKYVFLGAHSILSNGFLYSRVGTAQIAMLASRRNIPVLVCCESLKFSQRVQLD 474
T+FNMD+ YVFLGAHSILSNGFLYSR GTA +AM A RRNIPVLVCCESLKFSQRVQLD
Sbjct: 460 DTIFNMDVDYVFLGAHSILSNGFLYSRAGTAMLAMSAKRRNIPVLVCCESLKFSQRVQLD 519
Query: 475 SVTSNELADPNDLVTIDSANPVQRRNNNGFLLQQFIKEREAQQKEVENSSK-QNNKSGSA 533
SVT NELADPNDLV ID NPV+RR N G LL QFIKER+ ++K++ +K + NK G
Sbjct: 520 SVTFNELADPNDLVNIDYENPVERRGNKGALLNQFIKERKFEKKKLAMENKPKGNKIGGK 579
Query: 534 NTNNATADEGKNVKD---KPILAEWEKSPNLHIFNIMYDLTPPDYIKKIITEFGSLPPSS 590
+ + + N +D K IL W++ P+L+I NI+YDLTPP+YIKK+ITEFG+LPPSS
Sbjct: 580 KGSEGESKDASNEEDSNSKNILDGWQELPSLNIVNILYDLTPPEYIKKVITEFGALPPSS 639
Query: 591 VPVVLREYKASA 602
VPV+LREYK SA
Sbjct: 640 VPVILREYKGSA 651
>SPAC21E11.06 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 467
Score = 274 bits (701), Expect = 2e-73
Identities = 150/376 (39%), Positives = 224/376 (58%), Gaps = 54/376 (14%)
Query: 225 LHPAITSLTLDYAFYKIIGSIPRCIAMLEAFQLVVRDYKTPEGTTLSRNLTSYLSHQIDF 284
+HPA+ L L A YKI GS RCI +L+ F++V++DY+TP GTTLSR+LT++++ QI +
Sbjct: 141 IHPAVIRLGLKLANYKIFGSNQRCIDLLKTFKIVIQDYQTPYGTTLSRHLTTHINSQIAY 200
Query: 285 LKKSRPLSVTMGNAIRWLKQEISLIDPSTPDSKAKKELCDKIAQFARERVQLADQLIIET 344
L +RPLS++MGNAIR+LK EIS++D D + K+ L +KI + R+R+ +A Q+I++
Sbjct: 201 LVSTRPLSISMGNAIRFLKLEISVLDIDLTDDEGKELLLEKIDSYIRDRIIIAGQVIVQA 260
Query: 345 ASQHIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQIVIVDSRPLFEGRKMAESLRNQGL 404
A++ I++G ILTY S + D+ +H A N GK F++V+VDSRP FEGR + L G+
Sbjct: 261 ATEKIQDGDVILTYLHSSTVNDVLIH-AKNVGKKFRVVVVDSRPEFEGRVCLKLLTEHGI 319
Query: 405 NVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYSRVGTAQIAMLASRRNIPVLVCCES 464
YV I+AL + ++ +FLG H++LSNG LYSR GT+ I++L N+PV+ CCES
Sbjct: 320 ECTYVMISALSYIM-QEVTKIFLGGHAMLSNGALYSRAGTSLISLLGHESNVPVIACCES 378
Query: 465 LKFSQRVQLDSVTSNELADPNDLVTIDSANPVQRRNNNGFLLQQFIKEREAQQKEVENSS 524
KF++R+QLDS+ NELA + LV
Sbjct: 379 YKFTERIQLDSLVYNELAPGDQLV------------------------------------ 402
Query: 525 KQNNKSGSANTNNATADEGKNVKDKP-ILAEWEKSPNLHIFNIMYDLTPPDYIKKIITEF 583
N D+ ++KP +LA W+ NL + ++ YD+TPP I + E
Sbjct: 403 ------------NMGVDD---FEEKPGVLANWKSVKNLKLLSLKYDVTPPRLITVCVCEM 447
Query: 584 GSLPPSSVPVVLREYK 599
G LP +SVP ++ E+K
Sbjct: 448 GLLPSTSVPAIINEFK 463
>At5g38640 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 642
Score = 257 bits (657), Expect = 3e-68
Identities = 150/395 (37%), Positives = 220/395 (54%), Gaps = 55/395 (13%)
Query: 205 QFTNQQSIASVKELIANREMLHPAITSLTLDYAFYKIIGSIPRCIAMLEAFQLVVRDYKT 264
Q+ + + ++ + +HPA+ + L Y I G RCIAML+AFQ VV+DY T
Sbjct: 297 QYEHGTQLPDLETKFFQLDPMHPAVYKVGLQYLSGDISGGNARCIAMLQAFQEVVKDYST 356
Query: 265 PEGTTLSRNLTSYLSHQIDFLKKSRPLSVTMGNAIRWLKQEISLIDPSTPDSKAKKELCD 324
P +L+R++T+ +S + FL + RPLS++MGNAIR++K I+ + + +S+AK L
Sbjct: 357 PPEKSLNRDMTAKISSYVSFLIECRPLSISMGNAIRFVKNRIAKLPITLSESEAKATLQS 416
Query: 325 KIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQIVIV 384
I +F E++ +AD +I++ A I +G +LTYG + + LH A K F++++V
Sbjct: 417 DIERFINEKIIVADTVIVKHAVTKIRDGDVLLTYGSPTAVEMVILH-AHELRKKFRVLVV 475
Query: 385 DSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYSRVGT 444
DSRP EG+ + L +G+N Y I A+ + + ++ VFLGA S+LSNG +YSRVGT
Sbjct: 476 DSRPKLEGQLLLRRLIKRGINCTYTHINAISYIMH-EVTKVFLGASSVLSNGTVYSRVGT 534
Query: 445 AQIAMLASRRNIPVLVCCESLKFSQRVQLDSVTSNELADPNDLVTIDSANPVQRRNNNGF 504
A +AM+A+ +PVLVCCE+ KF +RVQLDS+ SNEL DPN +
Sbjct: 535 ACVAMVANAFRVPVLVCCEAYKFHERVQLDSICSNELGDPNAI----------------- 577
Query: 505 LLQQFIKEREAQQKEVENSSKQNNKSGSANTNNATADEGKNVKDKPILAEWEKSPNLHIF 564
EV N G TNNA NL
Sbjct: 578 -------------SEVHGREDINYLDGL--TNNA---------------------NLQFL 601
Query: 565 NIMYDLTPPDYIKKIITEFGSLPPSSVPVVLREYK 599
N+MYD TP DYI IIT++G +PP+SVPV++REY+
Sbjct: 602 NLMYDATPSDYISMIITDYGMVPPTSVPVIVREYQ 636
>Hs14165262 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 523
Score = 237 bits (604), Expect = 4e-62
Identities = 145/392 (36%), Positives = 211/392 (52%), Gaps = 59/392 (15%)
Query: 205 QFTNQQSIASVKELIANREMLHPAITSLTLDYAFYKIIGSIPRCIAMLEAFQLVVRDYKT 264
Q++ Q S+ + ++ ++HPA+ L L Y+ + GS RCIA+L A Q V++DY T
Sbjct: 185 QYSRQNSLTQFMSIPSS--VIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTT 242
Query: 265 PEGTTLSRNLTSYLSHQIDFLKKSRPLSVTMGNAIRWLKQEISLIDPSTPDSKAKKELCD 324
P LSR+L + L + FL + RPLS +M NAI++L +EI+ + S + +AK EL
Sbjct: 243 PPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRA 302
Query: 325 KIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQIVIV 384
I ++ +E++ LA Q I A Q I G IL YGCS +++ + L A G+ F++V+V
Sbjct: 303 AIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRI-LQEAWTEGRRFRVVVV 361
Query: 385 DSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYSRVGT 444
DSRP EGR SL + G+ Y+ I A V ++ V LGAH++L+NG + SRVGT
Sbjct: 362 DSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVL-PEVSKVLLGAHALLANGSVMSRVGT 420
Query: 445 AQIAMLASRRNIPVLVCCESLKFSQRVQLDSVTSNELADPNDLVTIDSANPVQRRNNNGF 504
AQ+A++A N+PVLVCCE+ KF +RVQ D+ SNEL DP+DL
Sbjct: 421 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDL----------------- 463
Query: 505 LLQQFIKEREAQQKEVENSSKQNNKSGSANTNNATADEGKNVKDKPILAEWEKSPNLHIF 564
K+ AN N + L +
Sbjct: 464 ------------------QCKRGEHVALANWQNHAS--------------------LRLL 485
Query: 565 NIMYDLTPPDYIKKIITEFGSLPPSSVPVVLR 596
N++YD+TPP+ + +ITE G +P SSVPVVLR
Sbjct: 486 NLVYDVTPPELVDLVITELGMIPCSSVPVVLR 517
>At2g44070 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 307
Score = 236 bits (601), Expect = 1e-61
Identities = 139/350 (39%), Positives = 201/350 (56%), Gaps = 56/350 (16%)
Query: 251 MLEAFQLVVRDYKTPEGTTLSRNLTSYLSHQIDFLKKSRPLSVTMGNAIRWLKQEISLID 310
ML+AFQ VV+DY TP TL+R++T+ +S + FL + RPLS++MGNAIR++K I+ +
Sbjct: 1 MLQAFQEVVKDYSTPPENTLNRDMTAQISSYVSFLIECRPLSISMGNAIRFVKNRIAKLP 60
Query: 311 PSTPDSKAKKELCDKIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVLTDLFLH 370
+ +S+AK L I +F E++ AD +I+E A I +G +LTYG S V+ + +H
Sbjct: 61 ITLSESEAKASLHSDIERFINEKIIGADTVIVEHAVTKIRDGDVLLTYGSSTVIEMILVH 120
Query: 371 NAINFGKNFQIVIVDSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMDIKYVFLGAH 430
A GK F++ +VDSRP +G+ + L +G+N Y ITA+ + + K VFLGA
Sbjct: 121 -AHELGKKFRVFVVDSRPKLQGKLLLRRLIKRGINCTYTHITAISYIMHQVTK-VFLGAS 178
Query: 431 SILSNGFLYSRVGTAQIAMLASRRNIPVLVCCESLKFSQRVQLD-SVTSNELADPNDLVT 489
S+ SNG +YSRVGTA +AM+A+ +PVLVCCE+ KF ++VQLD S+ SNEL DPN
Sbjct: 179 SVFSNGTVYSRVGTACVAMVANAFRVPVLVCCEAYKFHEKVQLDYSICSNELGDPN---- 234
Query: 490 IDSANPVQRRNNNGFLLQQFIKEREAQQKEVENSSKQNNKSGSANTNNATADEGKNVKDK 549
+ + V R + +L + TNNA
Sbjct: 235 --AISKVHGREDINYL--------------------------NGLTNNA----------- 255
Query: 550 PILAEWEKSPNLHIFNIMYDLTPPDYIKKIITEFGSLPPSSVPVVLREYK 599
L N+MYD TP DYI IIT++G +PP+SVPV++REY+
Sbjct: 256 ----------KLKFLNLMYDATPSDYISMIITDYGMVPPTSVPVIVREYQ 295
>At1g48970 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 756
Score = 224 bits (570), Expect = 4e-58
Identities = 135/380 (35%), Positives = 200/380 (52%), Gaps = 54/380 (14%)
Query: 205 QFTNQQSIASVKELIANREMLHPAITSLTLDYAFYKIIGSIPRCIAMLEAFQLVVRDYKT 264
Q+ + ++ + +H A+ + L + I G RCIAML+AFQ + DY T
Sbjct: 405 QYERSNQLPNLSSNFFTLDSIHHAVYKVGLQHLAGDISGDNARCIAMLQAFQEAIEDYST 464
Query: 265 PEGTTLSRNLTSYLSHQIDFLKKSRPLSVTMGNAIRWLKQEISLIDPSTPDSKAKKELCD 324
P L+ +LT+ ++ + FL + RPLS++MGNAIR+LK +I + + +S+AK LC
Sbjct: 465 PPMKDLTMDLTAKINGYVSFLIECRPLSMSMGNAIRFLKNQIRKLPVNLSESEAKSSLCS 524
Query: 325 KIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQIVIV 384
I +F E+ +AD+ I++ A I +G +LTYG S V+ + L+ A GK F++VIV
Sbjct: 525 DIGRFIDEKTIIADKAIVQHAVTKIRDGEVLLTYGFSCVVEMILLY-AHEIGKKFRVVIV 583
Query: 385 DSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYSRVGT 444
DSRP EG+K+ L +GL+ Y I A+ + + VFLGA SI SNG LY+RVGT
Sbjct: 584 DSRPNLEGQKLLRRLVTRGLDCTYTHINAISYIMR-EATRVFLGASSIYSNGTLYARVGT 642
Query: 445 AQIAMLASRRNIPVLVCCESLKFSQRVQLDSVTSNELADPNDLVTIDSANPVQRRNNNGF 504
+ IAM+A+ ++PV+VCCE+ KF +RV LDS+ SNEL DP+ + I
Sbjct: 643 SCIAMVANAFSVPVIVCCEAYKFHERVLLDSICSNELGDPDAVANIP------------- 689
Query: 505 LLQQFIKEREAQQKEVENSSKQNNKSGSANTNNATADEGKNVKDKPILAEWEKSPNLHIF 564
S + N K NN NL
Sbjct: 690 ------------------SFRTNAKHSKTMDNN---------------------KNLQFL 710
Query: 565 NIMYDLTPPDYIKKIITEFG 584
N+MYD TP +YI I++++G
Sbjct: 711 NLMYDSTPSEYISMIVSDYG 730
>7291571 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 626
Score = 194 bits (492), Expect = 4e-49
Identities = 103/271 (38%), Positives = 161/271 (59%), Gaps = 2/271 (0%)
Query: 221 NREMLHPAITSLTLDYAFYKIIGSIPRCIAMLEAFQLVVRDYKTPEGTTLSRNLTSYLSH 280
N ++HP+I L + YA ++GS RCIA L A + VV D++TP R+L + + H
Sbjct: 303 NDPLVHPSIARLGVQYAKRTVVGSNARCIAFLHALRQVVHDFETPAKKEFGRSLDAAVKH 362
Query: 281 QIDFLKKSRPLSVTMGNAIRWLKQEISLIDPSTPDSKAKKELCDKIAQFARERVQLADQL 340
+D L K RPL+V++ NA + K +++ + P++++K+ L I + ++ A Q
Sbjct: 363 HVDHLHKCRPLAVSVSNAYKQFKNQLTQLPADVPETESKELLVHFIDTYIENQIGKAAQA 422
Query: 341 IIETASQHIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQIVIVDSRPLFEGRKMAESLR 400
I + I +G +LT+ CS L A F++++VDSRP EG+++ L
Sbjct: 423 ISGFLQEKITDGDVLLTFACSS-LIQFICEEAKRRQVAFRVIVVDSRPGCEGQELLRRLH 481
Query: 401 NQGLNVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYSRVGTAQIAMLASRRNIPVLV 460
G+ YV I A+G V K V LGAH++L+NG++ +R GTAQ+A++A+ N+PVLV
Sbjct: 482 ATGIPCTYVLINAVGYVMAEATK-VLLGAHALLANGYVMARTGTAQVALVANAHNVPVLV 540
Query: 461 CCESLKFSQRVQLDSVTSNELADPNDLVTID 491
CCE+ KFS+R Q D++ NEL+DPN LV D
Sbjct: 541 CCETHKFSERFQTDAIVYNELSDPNQLVRGD 571
>Hs4503503 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 305
Score = 77.4 bits (189), Expect = 6e-14
Identities = 64/223 (28%), Positives = 113/223 (49%), Gaps = 6/223 (2%)
Query: 246 PRCIAMLEAFQLVVRDYKTPEGTTLSRNLTSYLSHQIDFLKKSRPLSVTMGNAIRWLKQE 305
P + + A + ++ K +G T+ + L + L+ I+ L SV + + +
Sbjct: 18 PDMASAVAAIRTLLEFLKRDKGETI-QGLRANLTSAIETLC-GVDSSVAVSSGGELFLRF 75
Query: 306 ISLIDPSTPD-SKAKKELCDKIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVL 364
ISL D SK KK + ++ F R R+ L+ I + I++G+TILT+ S+V+
Sbjct: 76 ISLASLEYSDYSKCKKIMIERGELFLR-RISLSRNKIADLCHTFIKDGATILTHAYSRVV 134
Query: 365 TDLFLHNAINFGKNFQIVIVDSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMDIKY 424
+ L A+ K F + + +S+P G+KMA++L + + V V A+G +
Sbjct: 135 LRV-LEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEK-ADL 192
Query: 425 VFLGAHSILSNGFLYSRVGTAQIAMLASRRNIPVLVCCESLKF 467
V +GA ++ NG + +++GT Q+A+ A +N P V ES KF
Sbjct: 193 VIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKF 235
>7290350 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 352
Score = 71.6 bits (174), Expect = 3e-12
Identities = 51/224 (22%), Positives = 100/224 (43%), Gaps = 4/224 (1%)
Query: 270 LSRNLTSYLSHQIDFLKKSRPLSVTMGNAIRWLKQEISLIDPSTPDSKAKKELCDKIAQF 329
L+R L ++ S+++ + + +D S P ++ L D + +
Sbjct: 81 LTREEFDLLHAKVQHFADDSQASLSLHKLVTQTSESNVSVDYSVPQHGLREALLDHLQEV 140
Query: 330 ARERVQLADQLIIETASQHIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQIVIVDSRPL 389
E ++ + ++ A +HI ILT G S+ + + FL AI + I++ + P
Sbjct: 141 ETELETSSENICVQ-AEEHIHSSEIILTLGHSRSVEN-FLKRAIKKRQFLTIIVAECAPA 198
Query: 390 FEGRKMAESLRNQ-GLNVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYSRVGTAQIA 448
G +A SL N+ + ++ +P A+ + + + V +G HS+L+NG L + G +A
Sbjct: 199 CRGHNLAASLANEKNVEIVVIPDAAIFAMMSR-VNKVIIGTHSVLANGGLRAACGAYTVA 257
Query: 449 MLASRRNIPVLVCCESLKFSQRVQLDSVTSNELADPNDLVTIDS 492
+ A ++PV+V K S + N + D++ DS
Sbjct: 258 LAAKHYSVPVIVLAPMYKLSPLHLCEQDAFNMVGCAEDVIPYDS 301
>CE05586 [J] KOG1467 Translation initiation factor 2B delta subunit
(eIF-2Bdelta/GCD2)
Length = 529
Score = 71.2 bits (173), Expect = 4e-12
Identities = 66/289 (22%), Positives = 127/289 (43%), Gaps = 19/289 (6%)
Query: 201 TMTSQFTNQQSIASVKELIANREM--------LHPAITSLTLDYAFYKIIGSIPRCIAML 252
T+ S + +++AS E A ++ +HPA +L KI CI +
Sbjct: 196 TLPSASDSDEAVASEIESTAIAQLDDATSFVHIHPAFLTLMAKAELEKIPDVETVCIQFI 255
Query: 253 EAFQLVVRDYKTPE------GTTLSRNLTSYLSHQIDFLKKSR--PLSVTMGNAIRWLKQ 304
AF+ +RD+ +T +L + Q+ + ++ PL +GN +R LK+
Sbjct: 256 AAFKEFLRDWTVEREKNNINASTFGHDLDLAIRPQLAHMTQNGHWPLPFALGNTVRLLKR 315
Query: 305 EISLIDPSTPDSKAKKELCDKIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVL 364
I ++ ST + K ++EL + A + I + + I++ ++ + V+
Sbjct: 316 TIKRLEEST-NMKCEEELQVYLEDTLAINFCHAYKAISQLLVRKIQQFKKVVVFDWCPVV 374
Query: 365 TDLFLHNAINFGKNFQIVIVDSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMDIKY 424
+ L + Q+ ++D+ G + +S +QG NV YV + ++
Sbjct: 375 NHVLLEAKQQI-PDMQLSVIDANSNGRGTRHVKSFVDQGYNVKYVTMKGASWA-SLASGV 432
Query: 425 VFLGAHSILSNGFLYSRVGTAQIAMLASRRNIPVLVCCESLKFSQRVQL 473
+ LG +I +NG + +R G + + A+ NIPV+V E KF + Q+
Sbjct: 433 LILGCSAIFANGAVAARKGALAVVLCANHYNIPVIVVAEHFKFIDKGQV 481
>At3g07300 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 384
Score = 70.9 bits (172), Expect = 5e-12
Identities = 49/185 (26%), Positives = 92/185 (49%), Gaps = 4/185 (2%)
Query: 305 EISLIDPSTPDSKAKKELCDKIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVL 364
E D S+ K K ++ + + Q +E +Q I E A +HI + ILT G S+ +
Sbjct: 163 ESKTADKSSLTRKLKHDVIEGVNQLIQEIAGCHEQ-IAEQAIEHIHQNEVILTLGSSRTV 221
Query: 365 TDLFLHNAINFGKNFQIVIVDSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMDIKY 424
+ FL A ++F++ + + P ++G +A+ L +GL + +A+ + + +
Sbjct: 222 LE-FLCAAKEKKRSFRVFVAEGAPRYQGHLLAKELVARGLQTTVITDSAVFAMISR-VNM 279
Query: 425 VFLGAHSILSNGFLYSRVGTAQIAMLASRRNIPVLVCCESLKFSQRVQLD-SVTSNELAD 483
V +GAH++++NG + VG A+ A + +P +V S K + V NEL
Sbjct: 280 VIIGAHAVMANGGVIGPVGVNMAALAAQKHAVPFVVLAGSHKLCPLYPHNPEVLLNELRS 339
Query: 484 PNDLV 488
P++L+
Sbjct: 340 PSELL 344
>CE00367 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 305
Score = 67.0 bits (162), Expect = 8e-11
Identities = 50/200 (25%), Positives = 98/200 (49%), Gaps = 5/200 (2%)
Query: 278 LSHQIDFLKKSRPLSVTMGNAIRWLKQEISLIDPSTPDSKAKKELCDKIAQFAR---ERV 334
L+ + L+K+ S ++ +A + SL + D + ++ D Q AR + V
Sbjct: 49 LNQVVAALEKTDYSSTSIRSAADLFTRFTSLAPAALLDQEDFSQVLDLYRQRARSFIKNV 108
Query: 335 QLADQLIIETASQHIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQIVIVDSRPLFEGRK 394
+ + I + A ILT+ SKV+ + L +A G + + + +S+P G+
Sbjct: 109 RGSRAKISKCARLFFTHHMNILTHSYSKVVLETIL-DAHKSGYHLHVWVTESQPDASGKL 167
Query: 395 MAESLRNQGLNVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYSRVGTAQIAMLASRR 454
+ E L+ G+ V + +G V I+ V +GA ++ G + +++GT + ++A R
Sbjct: 168 VFEELKKNGVPTTLVLDSCVGYVMER-IQAVLVGAEGVMETGGIINKIGTVNVCIIAKSR 226
Query: 455 NIPVLVCCESLKFSQRVQLD 474
++PV VC E++KF + L+
Sbjct: 227 HVPVYVCAETIKFVREFPLN 246
>At1g72340 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 362
Score = 66.2 bits (160), Expect = 1e-10
Identities = 49/163 (30%), Positives = 85/163 (52%), Gaps = 11/163 (6%)
Query: 316 SKAKKELCDKIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVLTDLFLHNAINF 375
+ AK L ++ +F + A ++I + I +G TIL +G S+V+ ++ L A
Sbjct: 147 NSAKSRLLERAEKFGEISCK-ARRIIAMLSQDFIFDGCTILVHGLSRVVLEI-LKTAAQN 204
Query: 376 GKNFQIVIVDSRPLFEGRKMAESLRNQGLNVLYVPITAL---GTVFNMD-IKYVFLGAHS 431
K F+++ + RP G L + L+ L +P+ L ++MD + VF+GA
Sbjct: 205 NKLFRVLCTEGRPDGTG-----VLLSSELSKLDIPVKLLLDSAVAYSMDEVDMVFVGADG 259
Query: 432 ILSNGFLYSRVGTAQIAMLASRRNIPVLVCCESLKFSQRVQLD 474
++ +G + + +GT QIA++A N PV V ES KF++ LD
Sbjct: 260 VVESGGIINMMGTYQIALVAHSMNKPVYVAAESYKFARLYPLD 302
>YKR026c [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 305
Score = 65.9 bits (159), Expect = 2e-10
Identities = 62/231 (26%), Positives = 108/231 (45%), Gaps = 14/231 (6%)
Query: 249 IAMLEAFQLVVRDYKTPEGTTLSRNLTSYLSHQIDFLKKSRPLSVTMGNA----IRWLKQ 304
IA +EA ++R KTPE + + + + + L KS P SV++ +R++ +
Sbjct: 24 IAAIEALVTLLR-IKTPE---TAAEMINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLR 79
Query: 305 EISLIDPSTPDSKAKKELCDKIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVL 364
+ L D + K+ + Q R + + I E I + IL +G S+ +
Sbjct: 80 NLHLYG----DWENCKQHLIENGQLFVSRAKKSRNKIAEIGVDFIADDDIILVHGYSRAV 135
Query: 365 TDLFLHNAINFGKNFQIVIVDSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMDIKY 424
L H A F + F+ V+ +SRP +G ++ L +G+ V + +A+G V + +
Sbjct: 136 FSLLNHAANKFIR-FRCVVTESRPSKQGNQLYTLLEQKGIPVTLIVDSAVGAVIDK-VDK 193
Query: 425 VFLGAHSILSNGFLYSRVGTAQIAMLASRRNIPVLVCCESLKFSQRVQLDS 475
VF+GA + +G + + VGT + +LA P V ES KF + L S
Sbjct: 194 VFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLSS 244
>Hs7657058 [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 351
Score = 63.5 bits (153), Expect = 9e-10
Identities = 49/238 (20%), Positives = 106/238 (43%), Gaps = 30/238 (12%)
Query: 288 SRPLSVTMGNAIRW----LKQEISLIDPSTPDSKAKKELCDKI-------------AQFA 330
++P T+GN +R +++E + + +S ++ L + AQ
Sbjct: 71 AQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYAQLQ 130
Query: 331 RERVQLADQLIIET----------ASQHIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQ 380
++ ++L++E A +HI I+T G S+ + + FL A K F
Sbjct: 131 SNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTV-EAFLKEAARKRK-FH 188
Query: 381 IVIVDSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYS 440
+++ + P +G +MA +L G+ + A+ V + + V +G +IL+NG L +
Sbjct: 189 VIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSR-VNKVIIGTKTILANGALRA 247
Query: 441 RVGTAQIAMLASRRNIPVLVCCESLKFSQRVQLDSVTSNELADPNDLVTIDSANPVQR 498
GT +A+ A + P++VC K S + + + ++ P +++ + +++
Sbjct: 248 VTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEK 305
>SPCC11E10.07c [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 341
Score = 61.6 bits (148), Expect = 3e-09
Identities = 56/259 (21%), Positives = 107/259 (40%), Gaps = 44/259 (16%)
Query: 332 ERVQLADQLIIETASQHIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQIVIVDSRPLFE 391
+R + Q I I +GS ILT+G S+ + + L A + F++ + +SRP
Sbjct: 116 QRARACRQRIAHLGYPLIRDGSVILTHGFSRGVAAVLLAAAKRHVR-FKVFVTESRPSGS 174
Query: 392 GRKMAESLRNQGLNVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYSRVGTAQIAMLA 451
G M +L+N + V +A+ N + V +GA ++ NG L +++GT Q+A+ A
Sbjct: 175 GCLMTRTLKNACIPTCMVLDSAVSFTMNR-VDLVLVGAEGVVENGGLINQIGTFQLAVFA 233
Query: 452 SRRNIPVLVCCESLKFSQRVQLDSVTSNELADPNDLVTIDSANPVQRRNNNGFLLQQFIK 511
+ P ES KF V++ ++ ++ ++ D +P
Sbjct: 234 KHAHKPFYAVAESHKF---VRMFPLSQYDIPFSRPILEFDDPSP---------------- 274
Query: 512 EREAQQKEVENSSKQNNKSGSANTNNATADEGKNVKDKPILAEWEKSPNLHIFNIMYDLT 571
E + + + S +N + +++ P L D+T
Sbjct: 275 -------ETVHPEPEPIPTPSDAIHNELIMNEEQIRNNPTL----------------DVT 311
Query: 572 PPDYIKKIITEFGSLPPSS 590
PP+++ +IT+ G + S
Sbjct: 312 PPEFVSGLITDLGIIDSKS 330
>SPAC343.14c [J] KOG1465 Translation initiation factor 2B beta subunit
(eIF-2Bbeta/GCD7)
Length = 393
Score = 57.8 bits (138), Expect = 5e-08
Identities = 78/340 (22%), Positives = 147/340 (42%), Gaps = 25/340 (7%)
Query: 179 LNSLSLDESSSFVPGISSVIPNT--MTSQFTNQQSIASVKELIAN-REMLHPAITSLTLD 235
++SL D S V G +V T + Q +Q ++V +LI R + + + +
Sbjct: 13 VSSLIADLKSRKVQGPFAVAVETALVMRQVISQTRWSTVDQLIDTVRAVGSTLVKAQPTE 72
Query: 236 YAFYKIIGSIPRCIAMLEAFQLVVRDYKTPEGTTLSRNLTSYLSHQIDF------LKKSR 289
++ II I R I E +Q +++ E +S + +S S + D ++
Sbjct: 73 FSCGNIIRRILRLIR--EEYQELLKTADENEKLIVSSSNSSSPSQKRDIPSNEKLVQSHE 130
Query: 290 PLSVTMGNAIRWLKQEISLIDPS----TPDSKAK--KELCDKIAQFARERVQLADQLIIE 343
P+SV M +++ L +L P+ DS+ ++ I ++ + D++ +
Sbjct: 131 PVSVQMYSSMLNLLGRPTLESPTHSKTVGDSRVTGGMDMRAVIISGIQDVIDELDKINTD 190
Query: 344 TASQ---HIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQIVIVDSRPLFE--GRKMAES 398
Q H+ ILT GCSK + + FL A K F +++ + P + MA+
Sbjct: 191 IEVQSMDHLHSNEIILTQGCSKTV-EAFLRFAAKKRK-FSVIVAEGFPNNQKGSHAMAKR 248
Query: 399 LRNQGLNVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYSRVGTAQIAMLASRRNIPV 458
L G++ + + + + + V LG H+IL NG L + G +A A PV
Sbjct: 249 LAQAGIDTTVISDATIFAIMSR-VNKVILGTHAILGNGGLVTYSGAQLVAQAARHHATPV 307
Query: 459 LVCCESLKFSQRVQLDSVTSNELADPNDLVTIDSANPVQR 498
+VC K S D + +L+ P+ +++ + + + R
Sbjct: 308 VVCSGIYKLSPVYPYDLESIIQLSSPDKIMSFNEGDLISR 347
>7301868 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 306
Score = 57.4 bits (137), Expect = 6e-08
Identities = 36/136 (26%), Positives = 68/136 (49%), Gaps = 2/136 (1%)
Query: 339 QLIIETASQHIEEGSTILTYGCSKVLTDLFLHNAINFGKNFQIVIVDSRPLFEGRKMAES 398
Q+I + A + I +G ILT+ S+V+ + + N K+F + + G +M +
Sbjct: 116 QVIAQQAQRFITDGCRILTHSRSRVVLKALITASQN-KKSFHVYVTQGGTGNSGEEMVKD 174
Query: 399 LRNQGLNVLYVPITALGTVFNMDIKYVFLGAHSILSNGFLYSRVGTAQIAMLASRRNIPV 458
L G++ + +A G V + +V +GA +++ +G + +R+GT + + A P
Sbjct: 175 LHAAGIDCTLILDSATGYVME-SVDFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPF 233
Query: 459 LVCCESLKFSQRVQLD 474
V ES KFS+ L+
Sbjct: 234 YVLAESFKFSRLYPLN 249
>At1g53900_2 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 402
Score = 55.5 bits (132), Expect = 2e-07
Identities = 46/160 (28%), Positives = 82/160 (50%), Gaps = 12/160 (7%)
Query: 316 SKAKKELCDKIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVLTDLFLHNAINF 375
+ AK + ++ +F + A +I + I +G TIL +G S+V+ ++ +A N
Sbjct: 194 NSAKSRVLERAEKFGEISCK-ARTIIAMLSQDFIFDGCTILVHGFSRVVFEILKTSAQN- 251
Query: 376 GKNFQIVIVDSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMD-IKYVFLGAHSILS 434
K F++ L G +A L + V + +A+ ++MD + VF+GA ++
Sbjct: 252 KKLFRV-------LCTGVLLANELAKLDIPVKLLIDSAVA--YSMDEVDMVFVGADGVVE 302
Query: 435 NGFLYSRVGTAQIAMLASRRNIPVLVCCESLKFSQRVQLD 474
+G + + +GT QIA++A N PV V ES KF++ LD
Sbjct: 303 SGGIINMMGTYQIALVAQSMNKPVYVAAESYKFARLYPLD 342
>At1g53880_2 [J] KOG1466 Translation initiation factor 2B alpha subunit
(eIF-2Balpha/GCN3)
Length = 402
Score = 55.5 bits (132), Expect = 2e-07
Identities = 46/160 (28%), Positives = 82/160 (50%), Gaps = 12/160 (7%)
Query: 316 SKAKKELCDKIAQFARERVQLADQLIIETASQHIEEGSTILTYGCSKVLTDLFLHNAINF 375
+ AK + ++ +F + A +I + I +G TIL +G S+V+ ++ +A N
Sbjct: 194 NSAKSRVLERAEKFGEISCK-ARTIIAMLSQDFIFDGCTILVHGFSRVVFEILKTSAQN- 251
Query: 376 GKNFQIVIVDSRPLFEGRKMAESLRNQGLNVLYVPITALGTVFNMD-IKYVFLGAHSILS 434
K F++ L G +A L + V + +A+ ++MD + VF+GA ++
Sbjct: 252 KKLFRV-------LCTGVLLANELAKLDIPVKLLIDSAVA--YSMDEVDMVFVGADGVVE 302
Query: 435 NGFLYSRVGTAQIAMLASRRNIPVLVCCESLKFSQRVQLD 474
+G + + +GT QIA++A N PV V ES KF++ LD
Sbjct: 303 SGGIINMMGTYQIALVAQSMNKPVYVAAESYKFARLYPLD 342
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.130 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,422,041
Number of Sequences: 60738
Number of extensions: 1134685
Number of successful extensions: 4425
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 4374
Number of HSP's gapped (non-prelim): 38
length of query: 602
length of database: 30,389,216
effective HSP length: 112
effective length of query: 490
effective length of database: 23,586,560
effective search space: 11557414400
effective search space used: 11557414400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)