ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2224 good G KOG2504 Carbohydrate transport and metabolism Monocarboxylate transporter
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2224 795410 793932 -493
(493 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR306c [G] KOG2504 Monocarboxylate transporter 498 e-141
YOL119c [G] KOG2504 Monocarboxylate transporter 333 3e-91
YNL125c [G] KOG2504 Monocarboxylate transporter 81 4e-15
7299667 [G] KOG2504 Monocarboxylate transporter 74 4e-13
Hs5730045 [G] KOG2504 Monocarboxylate transporter 62 2e-09
7290288 [G] KOG2504 Monocarboxylate transporter 60 6e-09
Hs4759120 [G] KOG2504 Monocarboxylate transporter 60 1e-08
YKL221w [G] KOG2504 Monocarboxylate transporter 57 8e-08
7293573 [G] KOG2504 Monocarboxylate transporter 56 1e-07
CE21446 [G] KOG2504 Monocarboxylate transporter 55 2e-07
CE20478 [G] KOG2504 Monocarboxylate transporter 55 2e-07
7293575 [G] KOG2504 Monocarboxylate transporter 55 3e-07
7292012 [G] KOG2504 Monocarboxylate transporter 55 3e-07
CE04864 [G] KOG2504 Monocarboxylate transporter 54 7e-07
Hs4759118 [G] KOG2504 Monocarboxylate transporter 52 3e-06
7293576 [G] KOG2504 Monocarboxylate transporter 51 5e-06
>YOR306c [G] KOG2504 Monocarboxylate transporter
Length = 521
Score = 498 bits (1283), Expect = e-141
Identities = 248/477 (51%), Positives = 319/477 (65%), Gaps = 6/477 (1%)
Query: 17 SPQSSRQLLMRKEVDVDNKFADLEATQTYNEQTRPVESGVKRPSFIQDDGLFYPEGGFAA 76
S S ++ +KEV NK D+E+ + E T K ++ F PEGGF A
Sbjct: 51 STSVSAKVYTKKEV---NKGTDIESQPHWGENTSSTHDSDKEEDSNEEIESF-PEGGFKA 106
Query: 77 WLVIFGCFCGFIPVFGMLNTIGVMENFIERNQLSSTSSSTVGWIFSIFSFVNFASCIFSG 136
W+V FGCF G I FG+LN+ GV+E+ ++ NQLSS S ST+GW+FS+F FV ASCI SG
Sbjct: 107 WVVTFGCFLGLIACFGLLNSTGVIESHLQDNQLSSESVSTIGWLFSLFLFVCSASCIISG 166
Query: 137 TYFDRNGAKGPLIVGSVLHVGGLFGMANSTELWQFILSFSIVTGLGNGILMSPLISVPSH 196
TYFDRNG + +IVG+V HV GLF ANST+ W FILSF+IV G GNGI++SPL+SVP+H
Sbjct: 167 TYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAH 226
Query: 197 YFLVKRXXXXXXXXXXXXXXXXXFPVILRKFFAMEKDSDPFYGFVWGLRTLGFVNLFLLI 256
YF +R FP++LR FF+M+ D+DP YGFVWG+RTLGF++L LL
Sbjct: 227 YFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLT 286
Query: 257 VALVLAKERLPHKKLNERERAIPTWRRVFNTYILQSFDIFGFKDLKYTFCVMGTVFGEIS 316
++++L KERLPH N ++ WR + YILQ FD F D+KY FCV+GTVF E+S
Sbjct: 287 LSIILVKERLPHVIENSKD-GESRWRYILRVYILQCFDAKAFLDMKYLFCVLGTVFSELS 345
Query: 317 IISGITYFTSYAMKQGLSQSDSYLLVMVVNLAGIPGRWLPGFFSDIFGRFNVAMITLVFL 376
I S +TY+ SYA G+S +D+Y L+M++N+ GIPGRW+PG+ SD FGRFNVA+ TL+ L
Sbjct: 346 INSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSDKFGRFNVAIATLLTL 405
Query: 377 GIITFVMWLPFATTRAVLXXXXXXXXXXXXXXXXXLPVCCGQISKTEEFGRRYSTMYFVV 436
I+ FV WLPF T + LPVCCGQISKTEEFG+RYSTMYFVV
Sbjct: 406 FIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVV 465
Query: 437 AFGTLVAVPITGAIIGPEKSFKGYDHYVIWCGVTSFVSAICYMISKTLAVGFNMKRF 493
FGTLV +PITGAII K+ Y HY+I+ G+ +FVSA+CY+IS+ VGF RF
Sbjct: 466 GFGTLVGIPITGAIIS-IKTTADYQHYIIFSGLATFVSAVCYIISRAYCVGFKWVRF 521
>YOL119c [G] KOG2504 Monocarboxylate transporter
Length = 501
Score = 333 bits (854), Expect = 3e-91
Identities = 177/458 (38%), Positives = 265/458 (57%), Gaps = 18/458 (3%)
Query: 38 DLEATQTYNEQTRPVESGVKRPSFIQDDGLFYPEGGFAAWLVIFGCFCGFIPVFGMLNTI 97
DL+ + N +R + + S I DD +P+GG AWLV+FG F G +PVFG++N++
Sbjct: 60 DLDVNKLTNVTSRVLNT--PEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSL 117
Query: 98 GVMENFIERNQLSSTSSSTVGWIFSIFSFVNFASCIFSGTYFDRNGAKGPLIVGSVLHVG 157
G +E++I ++QL++ SSST+ WIFS++ ++F SCI SG YFDRNG+ G + G+V++ G
Sbjct: 118 GAIESYISKHQLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAG 177
Query: 158 GLFGMANSTELWQFILSFSIVTGLGNGILMSPLISVPSHYFLVKRXXXXXXXXXXXXXXX 217
GLF +AN +WQFIL+FS+ +GLG GILM+PLI + +FL +R
Sbjct: 178 GLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGG 237
Query: 218 XXFPVILRKFFAMEKDSDPFYGFVWGLRTLGFVNLFLLIVALVLAKERL-PHKKLNERER 276
FP++LRK + GF W +R L F+ L LI A VLA+ER P + + +
Sbjct: 238 IVFPIMLRKLYKE-------VGFQWAIRILSFICLTCLICASVLARERTKPVVQPFKSKA 290
Query: 277 AIPTWRRVFNTYILQSFDIFGFKDLKYTFCVMGTVFGEISIISGITYFTSYAMKQGLSQS 336
+ W YI F+ F + K+ F +G F E S+ S TY SY+M +G +++
Sbjct: 291 EVAKW------YISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTEN 344
Query: 337 DSYLLVMVVNLAGIPGRWLPGFFSDIF-GRFNVAMITLVFLGIITFVMWLPFATTRAVLX 395
+Y ++ N GI GR++PG+F+D F GRFNV +IT+ + FVMWLPF VL
Sbjct: 345 VAYTMITASNAVGILGRYIPGYFADKFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLW 404
Query: 396 XXXXXXXXXXXXXXXXLPVCCGQISKTEEFGRRYSTMYFVVAFGTLVAVPITGAIIGPEK 455
PVC GQISKT +FG+RY+T+Y + A T+ +PI G +IG +
Sbjct: 405 AYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIG-KG 463
Query: 456 SFKGYDHYVIWCGVTSFVSAICYMISKTLAVGFNMKRF 493
+ Y+H++I+ A CY+IS+ + VG + +F
Sbjct: 464 TVANYNHFIIFNSALMAAGAACYIISRHICVGAKLCKF 501
>YNL125c [G] KOG2504 Monocarboxylate transporter
Length = 673
Score = 80.9 bits (198), Expect = 4e-15
Identities = 92/421 (21%), Positives = 159/421 (36%), Gaps = 21/421 (4%)
Query: 70 PEGGFAAWLVIFGCFCGFIPVFGMLNTIGV-MENFIERNQLSSTSSSTVGWIFSIFSFVN 128
P+GG+ W+V F F +G + GV + ++ + S I + F+
Sbjct: 207 PDGGYG-WVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLG 265
Query: 129 FASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTELWQFILSFSIVTGLGNGILMS 188
G + ++ G + + + +T+LWQ ++ + G ++
Sbjct: 266 QLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFV 325
Query: 189 PLISVPSHYFLVKRXXXXXXXXXXXXXXXXXFPVILRKFFAMEKDSDPFYGFVWGLRTLG 248
P +V +FL KR + + K + F W LR +G
Sbjct: 326 PATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLS------DFGNTRWCLRIIG 379
Query: 249 FVNLFLLIVALVLAKERLPHKKLNERERAIPTWRRVFNTYILQSFDIFGFKDLKYTFCVM 308
++VA+ L KER P + + + R +F Q +F K + F V+
Sbjct: 380 ISCSISVLVAIALLKERNPTPAIG-----LKSPRAMFE----QLKAMFSLKVITKPFVVL 430
Query: 309 GTVFGEISIIS-GITYFT--SYAMKQGLSQSDSYLLVMVVNLAGIPGRWLPGFFSDIFGR 365
++ ++ + + FT SYA+ +GLS D+ L ++N + GR L G D FGR
Sbjct: 431 IALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFGR 490
Query: 366 FNVAMITLVFLGIITFVMWLPFATTRAVLXXXXXXXXXXXXXXXXXLPVCCGQISKTEEF 425
NV ++ L I F W+P A T L V + K EEF
Sbjct: 491 ANVTIVLTTLLTIYMFAFWIP-AHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEF 549
Query: 426 GRRYSTMYFVVAFGTLVAVPITGAIIGPEKSFKGYDHYVIWCGVTSFVSAICYMISKTLA 485
++ + + A LV I A+ + Y H I+CG + I I + +
Sbjct: 550 LPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYS 609
Query: 486 V 486
+
Sbjct: 610 I 610
>7299667 [G] KOG2504 Monocarboxylate transporter
Length = 571
Score = 74.3 bits (181), Expect = 4e-13
Identities = 81/339 (23%), Positives = 131/339 (37%), Gaps = 37/339 (10%)
Query: 70 PEGGFAAWLVIFGCFCGFIPVFGMLNTIGVMENFIERNQL---SSTSSSTVGWIFSIFSF 126
P+GG AWLV+ F +FG +NT GV+ + + +SS I ++
Sbjct: 33 PDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIG 92
Query: 127 VNFASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTE-LWQFILSFSIVTGLGNGI 185
F +G D+ G + G VL GGL + TE + ++ I+ GLG +
Sbjct: 93 TTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAAL 152
Query: 186 LMSPLISVPSHYFLVKRXXXXXXXXXXXXXXXXXFPVILRKFFAMEKDSDPFYGFVWGLR 245
+P +++ HYF P L K YG LR
Sbjct: 153 AYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGS-------YGLEGTLR 205
Query: 246 TLGFVNLFLLIVALV---LAKERLPHKKLNERERAIPTWRRVFNTYILQSFDIFGFKDLK 302
+ V+ F+++ + V L P KK R R R + N I + + +
Sbjct: 206 IMSLVSAFIILCSFVYKPLHPPPEPPKKKPGRSRINLFLRSIINVEIWKR-----KRFVI 260
Query: 303 YTFCVMGTVFGEISIISGITYFTSYA-----MKQGLSQSDSYLLVMVVNLAGIPGRWLPG 357
+ CV +FG YF Y +K D L VM + + GR + G
Sbjct: 261 WALCVPLALFG---------YFVPYVHMMQFVKTTFPGEDVNLPVMCIGITSGIGRLIFG 311
Query: 358 FFSDIFG--RFNVAMITLVFLGIITFVMWLPFATTRAVL 394
+D+ G R + ++LV +G++T + LP + +L
Sbjct: 312 VIADMPGVNRMYLQQLSLVSIGLVTLL--LPLTNSYVIL 348
>Hs5730045 [G] KOG2504 Monocarboxylate transporter
Length = 613
Score = 62.4 bits (150), Expect = 2e-09
Identities = 59/317 (18%), Positives = 128/317 (39%), Gaps = 18/317 (5%)
Query: 70 PEGGFAAWLVIFGCFCGFIPVFGMLNTIGVMENFI--ERNQLSSTSSSTVGWIFSI-FSF 126
PEGGF W+V+F +FG+ N++G++ + + E + + W+ ++
Sbjct: 169 PEGGFG-WVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGM 227
Query: 127 VNFASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTELWQFILSFSIVTGLGNGIL 186
+ F S I S + DR G + G+ + GL + ++ L ++ I+ G G
Sbjct: 228 IFFCSPIVS-IFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFA 286
Query: 187 MSPLISVPSHYFLVKRXXXXXXXXXXXXXXXXXFPVILRKFFAMEKDSDPFYGFVWGLRT 246
P + + HYF + FP ++R K + F L T
Sbjct: 287 FQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQ----VLST 342
Query: 247 LGFVNLFLLIVALVLAKERLPHKKLNERERAIPTWRRVFNTYILQSFDIFGFKDLKYTFC 306
+F+L++ + + LP + +R + T + F + + F++ F+ Y
Sbjct: 343 F----MFVLMLLSLTYRPLLPSSQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRTYRIW 398
Query: 307 VMGTVFGEISIISGITYFTSYAMKQGLSQSDSYLLVMVVNLAGIPGRWLPGFFSDIFGRF 366
G + + Y ++ ++++L++ + GR + G SD
Sbjct: 399 AFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISD----- 453
Query: 367 NVAMITLVFLGIITFVM 383
++ + ++L +++F++
Sbjct: 454 SIPGLKKIYLQVLSFLL 470
>7290288 [G] KOG2504 Monocarboxylate transporter
Length = 715
Score = 60.5 bits (145), Expect = 6e-09
Identities = 40/133 (30%), Positives = 61/133 (45%), Gaps = 3/133 (2%)
Query: 70 PEGGFAAWLVIFGCFCGFIPVFGMLNTIGVMENFIERNQLSSTSSSTVGWIFSIFSFVNF 129
P+GG+ W+V+FG F I GM + G+ N E + WI SI V F
Sbjct: 118 PDGGWG-WVVVFGSFMIHIVTDGMTYSFGIFYN--EFLDYFNEGKGYTAWIASIMVGVTF 174
Query: 130 ASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTELWQFILSFSIVTGLGNGILMSP 189
+S S ++ +R G + I GS+L + + + I++ TGLG G++ P
Sbjct: 175 SSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLP 234
Query: 190 LISVPSHYFLVKR 202
I + YF KR
Sbjct: 235 AIVSVTQYFEAKR 247
>Hs4759120 [G] KOG2504 Monocarboxylate transporter
Length = 478
Score = 59.7 bits (143), Expect = 1e-08
Identities = 75/328 (22%), Positives = 127/328 (37%), Gaps = 64/328 (19%)
Query: 70 PEGGFAAWLVIFGCFC--GFIPVFGMLNTIGVMENFIERNQLSSTSSSTVGWIFSIFSFV 127
P+GG+ W+V+ F GF F T+ F E Q+ T+ S + WI SI V
Sbjct: 14 PDGGWG-WIVVGAAFISIGFSYAFPKAVTVF----FKEIQQIFHTTYSEIAWISSIMLAV 68
Query: 128 NFASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTELWQFILSFSIVTGLGNGILM 187
+A S ++ G++ +I G +L G+ + S+ + Q L+ +TGLG +
Sbjct: 69 MYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNL 128
Query: 188 SPLISVPSHYFLVKRXXXXXXXXXXXXXXXXXFPVILRKFFAMEKDSDPFYGFVWGLRTL 247
P +++ YF KR PV L PF +++ T
Sbjct: 129 QPALTIIGKYFYRKRPMANGLAMAGS-------PVFLSSL-------APFNQYLF--NTF 172
Query: 248 GFVNLFLLIVALVL----------------AKERLPHKKLNERERAIP--------TWRR 283
G+ FL++ +L+L + +K + + P TW +
Sbjct: 173 GWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEK 232
Query: 284 VFNTYILQSFDIFGFKDLKYTFCVMGTVFGEISIISGITYFTSYAMKQGLSQSDSYLLVM 343
V N Y+ D FK + + G V + + I + YA QG+ + + L+
Sbjct: 233 V-NKYL----DFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLS 287
Query: 344 VVNLAGIPGRWLPGFFSDIFGRFNVAMI 371
V+ F D+F R +V +I
Sbjct: 288 VM------------AFVDMFARPSVGLI 303
>YKL221w [G] KOG2504 Monocarboxylate transporter
Length = 473
Score = 56.6 bits (135), Expect = 8e-08
Identities = 88/422 (20%), Positives = 159/422 (36%), Gaps = 48/422 (11%)
Query: 70 PEGGFAAWLVIFGCFCGFIPVFGMLNTIGV-MENFIERNQLSSTS----SSTVGWIFSIF 124
P+GG+ W ++ +G + + + +++E N + S +S G FS
Sbjct: 36 PDGGYG-WFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCG 94
Query: 125 SF----VNFASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTELWQFILSFSIVTG 180
F + + IFS + + +G + L A S LW+ L+ ++ G
Sbjct: 95 LFFAPVITWLYHIFSIQFI--------IGLGILFQGAALLLAAFSVTLWEIYLTQGVLIG 146
Query: 181 LGNGILMSPLISVPSHYFLVKRXXXXXXXXXXXXXXXXXFPVILRKFFAMEKDSDPFYGF 240
G + P +++ +F KR F + ++ G
Sbjct: 147 FGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKR-------GV 199
Query: 241 VWGLRTLGFVNLFLLIVALVLAKERLPHKKLNERERAIPTWRRVFNTYILQSFDI---FG 297
W L + L +AL+L R H+ L + +R+ + + +L +F + FG
Sbjct: 200 KWALIAQCIICTSLSTIALMLT--RTTHQGLRQHKRSYKF--ELLDYDVLSNFAVWLLFG 255
Query: 298 FKDLKYTFCVMGTVFGEISIISGITYFTSYAMKQGLSQSDSYLLVMVVNLAGIPGRWLPG 357
F +F ++G V S +S T Y KQG SY+ M V++ + GR + G
Sbjct: 256 F----VSFAMLGYVVLLYS-LSDFTVSLGYTSKQG-----SYVSCM-VSVGSLLGRPIVG 304
Query: 358 FFSDIFGRFNVAMITLVFLGIITFVMWLPFATTRAVLXXXXXXXXXXXXXXXXXLPVCCG 417
+D +G V MI + + I+ + MW+P + +
Sbjct: 305 HIADKYGSLTVGMILHLVMAILCWAMWIPCKNLATAIRFGLLVGSIMGTIWPTIASIVTR 364
Query: 418 QISKTEEFGRRYSTMYFVVAFGTLVAVPITGAIIGPEKSFKGYDHY--VIWCGVTSFVSA 475
+ + G ST F+ AF + PI G + + G D+Y I+ G F +
Sbjct: 365 IVGLQKLPGTFGSTWIFMAAFA--LVAPIIGLELRSTDT-NGNDYYRTAIFVGFAYFGVS 421
Query: 476 IC 477
+C
Sbjct: 422 LC 423
>7293573 [G] KOG2504 Monocarboxylate transporter
Length = 563
Score = 55.8 bits (133), Expect = 1e-07
Identities = 51/214 (23%), Positives = 92/214 (42%), Gaps = 14/214 (6%)
Query: 48 QTRPVESGVKRPSFIQDDGLFYPEGGFAAWLVIFGCFCGFIPVFGMLNTIGVMENFIERN 107
Q+RP K S+ L P+GG+ LV G F L + G++ ++
Sbjct: 16 QSRPAYQMKKSKSYT----LEAPDGGWGI-LVCIGMALPFTSALAALPSFGLVFGEFLKS 70
Query: 108 QLSSTSSSTVGWIFSIFSFVNFASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTE 167
+ TS+ + + FS ++FA +FSG+ F R G + + G +L+ G +T
Sbjct: 71 IGAETSAMAI-ITSAFFSSMSFAG-LFSGSLFQRFGMRQVGVTGGILYFLGTGMQLFATS 128
Query: 168 LWQFILSFSIVTGLGNGILMSPLISVPSHYFLVKRXXXXXXXXXXXXXXXXXFPVILRKF 227
I++FS+V G G+++ + +HYF+ R +P++++K
Sbjct: 129 TLHLIMAFSVVQGFAFGLMVPTCYTTFNHYFVKNRVMWMSFAQTLIGLGSMLYPIVMQKL 188
Query: 228 FAMEKDSDPFYGFVWGLRTLGFVNLFLLIVALVL 261
+ +YGF L L +N + LV+
Sbjct: 189 MS-------WYGFRGCLLILTGLNAHAVFGMLVM 215
>CE21446 [G] KOG2504 Monocarboxylate transporter
Length = 666
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/236 (23%), Positives = 95/236 (39%), Gaps = 16/236 (6%)
Query: 30 VDVDNKFADLEATQTYNEQTRPVESGVKRPSFIQDDGLFYPEGGFAAWLVIFGCFCGFIP 89
+D + K + T N + + E G P P+GG+ W+V+ F +
Sbjct: 10 LDAEKKEVTVAVTAAENFEEQVEEVGKVTP----------PDGGYG-WVVVAASFLVNMA 58
Query: 90 VFGMLNTIGVMENFIERNQLSSTSSSTVGWIFSIFSFVNFASCIFSGTYFDRNGAKGPLI 149
V G++ T G + I +Q STS G + SI + + + + ++ + G + I
Sbjct: 59 VDGVIYTCGKILVPIWADQFGSTS--VAGAVISILTGCYYLAGPLASSFVNVFGIRSVAI 116
Query: 150 VGSVLHVGGLFGMANSTELWQFILSFSIVTGLGNGILMSPLISVPSHYFLVKRXXXXXXX 209
GS+L ++ +W+ L F ++ G+G G + P I + S YF KR
Sbjct: 117 AGSILATTAFLLSRFASTIWELYLLFGVLGGIGFGCMYLPSIVILSTYFAKKRSVATGIA 176
Query: 210 XXXXXXXXXXFPVILRKFF-AMEKDSDPFYGFVWGLRTLGFVNLFLLIVALVLAKE 264
F I F KD F ++ + G +LF L+ A + A E
Sbjct: 177 VCGSGIGTMVFSTINGPVFDYFGKDVGSFMVYLAAIAISG--SLFSLLFAPLKATE 230
>CE20478 [G] KOG2504 Monocarboxylate transporter
Length = 571
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/236 (23%), Positives = 95/236 (39%), Gaps = 16/236 (6%)
Query: 30 VDVDNKFADLEATQTYNEQTRPVESGVKRPSFIQDDGLFYPEGGFAAWLVIFGCFCGFIP 89
+D + K + T N + + E G P P+GG+ W+V+ F +
Sbjct: 10 LDAEKKEVTVAVTAAENFEEQVEEVGKVTP----------PDGGYG-WVVVAASFLVNMA 58
Query: 90 VFGMLNTIGVMENFIERNQLSSTSSSTVGWIFSIFSFVNFASCIFSGTYFDRNGAKGPLI 149
V G++ T G + I +Q STS G + SI + + + + ++ + G + I
Sbjct: 59 VDGVIYTCGKILVPIWADQFGSTS--VAGAVISILTGCYYLAGPLASSFVNVFGIRSVAI 116
Query: 150 VGSVLHVGGLFGMANSTELWQFILSFSIVTGLGNGILMSPLISVPSHYFLVKRXXXXXXX 209
GS+L ++ +W+ L F ++ G+G G + P I + S YF KR
Sbjct: 117 AGSILATTAFLLSRFASTIWELYLLFGVLGGIGFGCMYLPSIVILSTYFAKKRSVATGIA 176
Query: 210 XXXXXXXXXXFPVILRKFF-AMEKDSDPFYGFVWGLRTLGFVNLFLLIVALVLAKE 264
F I F KD F ++ + G +LF L+ A + A E
Sbjct: 177 VCGSGIGTMVFSTINGPVFDYFGKDVGSFMVYLAAIAISG--SLFSLLFAPLKATE 230
>7293575 [G] KOG2504 Monocarboxylate transporter
Length = 645
Score = 54.7 bits (130), Expect = 3e-07
Identities = 52/189 (27%), Positives = 82/189 (42%), Gaps = 5/189 (2%)
Query: 16 LSPQSSRQLLMRKEVDVDNKFADLEATQTYNEQTRPVESGVKRPSFIQDDGLFY--PEGG 73
L + + QLL + K A T + + P + K+ D G + P+GG
Sbjct: 24 LPEEQAEQLLPKNGSAGQTKIAPPTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGG 83
Query: 74 FAAWLVIFGCFCGFIPVFGMLNTIGVMENFIERNQLSSTSSSTVGWIFSIFSFVNFASCI 133
+ WLV + F + G++ F +R SSS + I + V+ + +
Sbjct: 84 WG-WLVSVASGVNILVTFALAQQFGIL--FRDRMAGLGISSSELTTIINTQIAVSAFTGL 140
Query: 134 FSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTELWQFILSFSIVTGLGNGILMSPLISV 193
+G F R + +VGSVL GLF M + +I+SFSI+ G G G+ +S
Sbjct: 141 LNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLA 200
Query: 194 PSHYFLVKR 202
+ YF VKR
Sbjct: 201 VNTYFKVKR 209
>7292012 [G] KOG2504 Monocarboxylate transporter
Length = 816
Score = 54.7 bits (130), Expect = 3e-07
Identities = 45/199 (22%), Positives = 82/199 (40%), Gaps = 11/199 (5%)
Query: 11 SRPAMLSPQSSRQLLMRKEVDVDNKFADLEATQTYNEQTRPVESGVKRPSFIQDDGLFY- 69
S P ++ S+ +R+ D++ A EA + EQ+ E D+ Y
Sbjct: 7 SNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYG 66
Query: 70 -----PEGGFAAWLVIFGCFCGFIPVFGMLNTIGV-MENFIERNQLSSTSSSTVGWIFSI 123
P+GG+ W++ F F + V G+ T G+ +E F+ TV W+ S+
Sbjct: 67 ELPPPPDGGYG-WVICFASFMCNMIVDGIAYTFGIFLEEFVA---YFHEGKGTVAWVGSL 122
Query: 124 FSFVNFASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTELWQFILSFSIVTGLGN 183
S V ++ ++ G + I GS++ ST + + ++ + G G
Sbjct: 123 LSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGF 182
Query: 184 GILMSPLISVPSHYFLVKR 202
G++ P + +YF KR
Sbjct: 183 GMIYLPAVVAVGYYFETKR 201
>CE04864 [G] KOG2504 Monocarboxylate transporter
Length = 556
Score = 53.5 bits (127), Expect = 7e-07
Identities = 36/136 (26%), Positives = 70/136 (51%), Gaps = 9/136 (6%)
Query: 70 PEGGFAAWLVIFGCFCGFIPVF--GMLNTIGVMENFIERNQLSSTSSSTV-GWIFSIFSF 126
P+GG+ W+V+ G F FI VF G + + G++ E+ + S++T+ I S+ +
Sbjct: 15 PDGGWG-WVVVIGSF--FIHVFADGFVYSFGILA---EKLMIEFNSNNTMTSLIVSMLTG 68
Query: 127 VNFASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTELWQFILSFSIVTGLGNGIL 186
+ + ++ G + I+G+ + G +TE+W F++S ++ G+G G++
Sbjct: 69 FTLGAGPLASAVCNKYGCRITTIIGAGVAFVGCLLSCFATEIWHFVISVGVIMGIGFGLV 128
Query: 187 MSPLISVPSHYFLVKR 202
P I + + YF KR
Sbjct: 129 YCPAIVIVTMYFESKR 144
>Hs4759118 [G] KOG2504 Monocarboxylate transporter
Length = 523
Score = 51.6 bits (122), Expect = 3e-06
Identities = 36/133 (27%), Positives = 65/133 (48%), Gaps = 3/133 (2%)
Query: 70 PEGGFAAWLVIFGCFCGFIPVFGMLNTIGVMENFIERNQLSSTSSSTVGWIFSIFSFVNF 129
P+GG+ W V F + +G++ T GV N + + + S+S + WI SI FV
Sbjct: 19 PDGGWG-WAVAVSFFFVEVFTYGIIKTFGVFFNDLMDS--FNESNSRISWIISICVFVLT 75
Query: 130 ASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFGMANSTELWQFILSFSIVTGLGNGILMSP 189
S + +R G + +++G +L G+ + S E+ ++ I++GLG P
Sbjct: 76 FSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLP 135
Query: 190 LISVPSHYFLVKR 202
+++ S YF +R
Sbjct: 136 TVTILSQYFGKRR 148
>7293576 [G] KOG2504 Monocarboxylate transporter
Length = 655
Score = 50.8 bits (120), Expect = 5e-06
Identities = 41/161 (25%), Positives = 71/161 (43%), Gaps = 4/161 (2%)
Query: 42 TQTYNEQTRPVESGVKRPSFIQDDGLFYPEGGFAAWLVIFGCFCGFIPVFGMLNTIGVME 101
TQ YN+ T+P + + S + D P+GG+ W+V +F L G++
Sbjct: 12 TQVYNDTTKPKKPKRRDKSDLGPD-FVAPDGGWG-WVVCLAAGLNNFFLFPALQQYGLI- 68
Query: 102 NFIERNQLSSTSSSTVGWIFSIFSFVNFASCIFSGTYFDRNGAKGPLIVGSVLHVGGLFG 161
+ R Q + I ++ ++ I +G F R + + G+ L G+F
Sbjct: 69 -YRVRMQSLGFDAKQTTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFL 127
Query: 162 MANSTELWQFILSFSIVTGLGNGILMSPLISVPSHYFLVKR 202
A T WQ+I+ S + G+G G+ M+ + YF +KR
Sbjct: 128 SAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKR 168
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.328 0.144 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,002,688
Number of Sequences: 60738
Number of extensions: 1022349
Number of successful extensions: 3136
Number of sequences better than 1.0e-05: 16
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 3113
Number of HSP's gapped (non-prelim): 21
length of query: 493
length of database: 30,389,216
effective HSP length: 110
effective length of query: 383
effective length of database: 23,708,036
effective search space: 9080177788
effective search space used: 9080177788
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)