ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2273 good P KOG1483 Inorganic ion transport and metabolism Zn2+ transporter ZNT1 and related Cd2+/Zn2+ transporters (cation diffusion facilitator superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2273 814322 813015 -436
(436 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR243c [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+ ... 424 e-118
YOR316c [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+ ... 385 e-107
SPAC23C11.14 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/... 275 1e-73
7292347 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+ ... 137 4e-32
Hs22041360 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn... 130 4e-30
Hs14141726 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn... 122 1e-27
Hs22041348 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn... 98 3e-20
At2g04620 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation dif... 93 7e-19
CE29581 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+ ... 91 3e-18
CE27065 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+ ... 91 3e-18
7299414 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation diffu... 87 5e-17
CE26955_2 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation dif... 85 2e-16
7298209 [P] KOG1482 Zn2+ transporter 84 3e-16
Hs8922155 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2... 82 2e-15
HsM4508043 [P] KOG1482 Zn2+ transporter 82 2e-15
Hs21361112 [P] KOG1482 Zn2+ transporter 82 2e-15
SPAC17D4.03c [P] KOG1484 Putative Zn2+ transporter MSC2 (cation ... 80 8e-15
Hs19424134 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation di... 79 1e-14
CE03664 [P] KOG1482 Zn2+ transporter 78 2e-14
Hs20070323_2 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation ... 78 3e-14
CE16617 [P] KOG1482 Zn2+ transporter 77 7e-14
CE16616 [P] KOG1482 Zn2+ transporter 77 7e-14
YDR205w [P] KOG1484 Putative Zn2+ transporter MSC2 (cation diffu... 75 1e-13
HsM7019533 [P] KOG1482 Zn2+ transporter 75 1e-13
Hs21359890 [P] KOG1482 Zn2+ transporter 75 1e-13
At2g46800 [P] KOG1482 Zn2+ transporter 75 3e-13
7296322 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+ ... 72 1e-12
At3g61940 [P] KOG1482 Zn2+ transporter 70 6e-12
At3g58810 [P] KOG1482 Zn2+ transporter 70 8e-12
7297930_2 [P] KOG1482 Zn2+ transporter 70 8e-12
Hs20540985 [P] KOG1482 Zn2+ transporter 69 1e-11
7302213 [P] KOG1482 Zn2+ transporter 69 2e-11
Hs22041687 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation di... 67 4e-11
ECU11g1510 [P] KOG1482 Zn2+ transporter 65 2e-10
Hs14210520 [P] KOG1482 Zn2+ transporter 65 2e-10
At2g29410 [P] KOG1482 Zn2+ transporter 62 1e-09
YPL224c [P] KOG1485 Mitochondrial Fe2+ transporter MMT1 and rela... 52 2e-06
YMR177w [P] KOG1485 Mitochondrial Fe2+ transporter MMT1 and rela... 51 4e-06
>YMR243c [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 442
Score = 424 bits (1090), Expect = e-118
Identities = 228/462 (49%), Positives = 288/462 (61%), Gaps = 47/462 (10%)
Query: 1 MLSGKEARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAK 60
M++GKE RI++LL +DT FF +E+ GYM HSLALIADSFHMLNDIISL++ALWAV+VAK
Sbjct: 1 MITGKELRIISLLTLDTVFFLLEITIGYMSHSLALIADSFHMLNDIISLLVALWAVDVAK 60
Query: 61 NKNPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCF 120
N+ PDAKYTYGWKRAEILGAL+NAVFLIALC SI+IEA+QR +PQEI NP+LVL VG
Sbjct: 61 NRGPDAKYTYGWKRAEILGALINAVFLIALCFSIMIEALQRLIEPQEIQNPRLVLYVGVA 120
Query: 121 GLVSNFIGLALFXXXXXXXXXXXXXXAPDLXXXXXXXXXXXXXXXXXXXXXXQTNGLDEG 180
GL+SN +GL LF + + +DE
Sbjct: 121 GLISNVVGLFLFHDHGSDSLHSHSHGSVESGNNDLDIESNATHSHSHASLPNDNLAIDED 180
Query: 181 SDYEP---ETIEDMMPHSIVERTFSPKSTPVXXXXXXXXXXXTGLLTEQHLNXXXXXXXX 237
+ P I +++P S+V R S +S P+ L + H
Sbjct: 181 AISSPGPSGQIGEVLPQSVVNR-LSNESQPL-------------LNHDDH-----DHSHE 221
Query: 238 XXXXXQRSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXX 297
RS+NMHGVFLHVLGDALGN+GVIA ALFIWKT++SWR+Y+DP V
Sbjct: 222 SKKPGHRSLNMHGVFLHVLGDALGNIGVIAAALFIWKTEYSWRYYSDPIVSLIITIIIFS 281
Query: 298 XXXXXXXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEI 357
+ASRILLQATPS +SAD ++ +IL++PGV++VHDFH+WNLTES+YIAS+HV+I
Sbjct: 282 SALPLSRRASRILLQATPSTISADQIQREILAVPGVIAVHDFHVWNLTESIYIASIHVQI 341
Query: 358 QSNPEEFMNIAQVIRSIFHRYGIHSATVQPEFVGSGAVTEDIARRFSRIAGGG------- 410
P++FM+ A++IR IFH++GIHSATVQPEFV SG V EDI RRFS IAGG
Sbjct: 342 DCAPDKFMSSAKLIRKIFHQHGIHSATVQPEFV-SGDVNEDIRRRFSIIAGGSPSSSQEA 400
Query: 411 -----------------VYGSTTNLTGCTIDENAQCNSETCL 435
YG+TT + C +D+ CN+ CL
Sbjct: 401 FDSHGNTEHGRKKRSPTAYGATTASSNCIVDDAVNCNTSNCL 442
>YOR316c [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 439
Score = 385 bits (988), Expect = e-107
Identities = 206/449 (45%), Positives = 275/449 (60%), Gaps = 28/449 (6%)
Query: 2 LSGKEARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKN 61
L K+ +I++LL++DT FF IE+ +GY+ HSLALIADSFHMLNDIISLV+ALWAVNVAKN
Sbjct: 3 LGSKQVKIISLLLLDTVFFGIEITTGYLSHSLALIADSFHMLNDIISLVVALWAVNVAKN 62
Query: 62 KNPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFG 121
+NPD+ YTYGWKRAEILGAL+NAVFLIALCVSILIEA+QR P I NPK VL VG G
Sbjct: 63 RNPDSTYTYGWKRAEILGALINAVFLIALCVSILIEALQRIIAPPVIENPKFVLYVGVAG 122
Query: 122 LVSNFIGLALFXXXXXXXXXXXXXXAPDLXXXXXXXXXXXXXXXXXXXXXXQTNGLDEGS 181
L+SN +GL LF + + + +
Sbjct: 123 LISNTVGLFLFHDNDQEHGHGHGHSHGGIFADHEMHMPSSHTHTHAHVDGIENTTPMDST 182
Query: 182 DYEPETIEDMMPHSIVERTFSPKSTPVXXXXXXXXXXXTGLLTEQHLNXXXXXXXXXXXX 241
D I ++MP++IV+ +F ++T + T H
Sbjct: 183 D----NISEIMPNAIVD-SFMNENTRLLTPENASKTPSYS--TSSH-TIASGGNYTEHNK 234
Query: 242 XQRSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXX 301
+RS+NMHGVFLHVLGDALGN+GV+ +A FIWKTD+SW++YTDP V
Sbjct: 235 RKRSLNMHGVFLHVLGDALGNIGVMLSAFFIWKTDYSWKYYTDPLVSLIITGIIFSSALP 294
Query: 302 XXXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNP 361
KAS+ILLQATPS +S D V+ D+L +PG++++HDFHIWNLTES++IAS+H+++ +P
Sbjct: 295 LSCKASKILLQATPSTLSGDQVEGDLLKIPGIIAIHDFHIWNLTESIFIASLHIQLDISP 354
Query: 362 EEFMNIAQVIRSIFHRYGIHSATVQPEFV--------------GSGAVTEDIARRFSRIA 407
E+F ++A+++RS HRYGIHSAT+QPEF+ G + ++ R +
Sbjct: 355 EQFTDLAKIVRSKLHRYGIHSATLQPEFITREVTSTERAGDSQGDHLQNDPLSLR-PKTY 413
Query: 408 GGGVYGSTTNLTGCTIDENAQCNSETCLQ 436
G G+ GST C ID+ A CN+ CL+
Sbjct: 414 GTGISGST-----CLIDDAANCNTADCLE 437
>SPAC23C11.14 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 387
Score = 275 bits (703), Expect = 1e-73
Identities = 158/404 (39%), Positives = 213/404 (52%), Gaps = 54/404 (13%)
Query: 5 KEARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNP 64
++ RI+ LL ID TFFFIE+I+GY + SLALIADSFHMLNDI+SL++ALWA +A + +
Sbjct: 6 RQTRIILLLGIDVTFFFIEIITGYAIDSLALIADSFHMLNDIVSLLVALWATRLAHSTSH 65
Query: 65 DAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVS 124
+ KYTYGW+RAEILGAL N VFLIALC+ I +EAI+RF +P ++NP L+ VG GL+S
Sbjct: 66 EPKYTYGWQRAEILGALSNGVFLIALCMFIFMEAIERFIEPPSVSNPTLMFFVGSLGLLS 125
Query: 125 NFIGLALFXXXXXXXXXXXXXXAPDLXXXXXXXXXXXXXXXXXXXXXXQTNGLDEGSDYE 184
NF+G+ LF D E
Sbjct: 126 NFVGIFLFHDHGHDHPHTHTAQNYDFP--------------------------------E 153
Query: 185 PETIEDMMPHSIVER----------------TFSPKSTPVXXXXXXXXXXXTGLLTEQHL 228
+ IE ++P +IV R + +S+P+ T H
Sbjct: 154 EDDIESVLPSTIVHRCNTSQQEVSHTHTQVADSATESSPLLSYTGNHNGAGTSKPVNNH- 212
Query: 229 NXXXXXXXXXXXXXQRSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVX 288
+R++NMHGVFLHVLGDALGN+GVI+ ALFI TD+SWRF DP +
Sbjct: 213 --GSIEQDAPKQTKKRNLNMHGVFLHVLGDALGNIGVISAALFIKYTDYSWRFLFDPCIS 270
Query: 289 XXXXXXXXXXXXXXXXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESL 348
A+ ILLQ P ++ DDV + I L GV SVH+ HIW L++
Sbjct: 271 ILLTFIILFSAIPLCKSAALILLQVAPQSIKLDDVSNLINHLDGVESVHELHIWQLSDVK 330
Query: 349 YIASVHVEI---QSNPEEFMNIAQVIRSIFHRYGIHSATVQPEF 389
IA+VHV + E + + IR++ +GI+ T+QPEF
Sbjct: 331 LIATVHVCVTLPDDKGESYTKLTTDIRNVLQSFGIYDVTIQPEF 374
>7292347 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 449
Score = 137 bits (344), Expect = 4e-32
Identities = 68/129 (52%), Positives = 97/129 (74%), Gaps = 2/129 (1%)
Query: 3 SGKEARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNK 62
SGK+ R+++++ + FFF+E+I GY+ +S+AL+ADSFHML DI +LVI+ +V ++ K
Sbjct: 5 SGKKCRLLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKK 64
Query: 63 NPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGL 122
+K T+GW RAE+LGALVNAVFL+ALC SI IEA +RF + + I P+L++IVG GL
Sbjct: 65 W--SKNTFGWARAEVLGALVNAVFLVALCFSITIEACKRFIEEEPIHEPELLVIVGALGL 122
Query: 123 VSNFIGLAL 131
+ N IGL L
Sbjct: 123 LVNVIGLCL 131
Score = 124 bits (310), Expect = 4e-28
Identities = 58/145 (40%), Positives = 90/145 (62%), Gaps = 2/145 (1%)
Query: 246 MNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXXXXK 305
MNM G FLHVL DALG++ V+ +A+ +WKT++ +R+Y DPA+ +
Sbjct: 195 MNMRGAFLHVLSDALGSIIVVISAVVVWKTEWKYRYYMDPALSIVLVVLILHSVWPLLRE 254
Query: 306 ASRILLQATPSNVSADDVKHDIL-SLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEEF 364
++ ILLQ P+++ D ++ +L + GV++VH+FH+W L IAS H+ + N E+
Sbjct: 255 SALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIRCR-NLSEY 313
Query: 365 MNIAQVIRSIFHRYGIHSATVQPEF 389
M IA+ ++ FH GIHS T+QPEF
Sbjct: 314 MKIAEKVKEFFHNEGIHSTTIQPEF 338
>Hs22041360 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 272
Score = 130 bits (327), Expect = 4e-30
Identities = 64/130 (49%), Positives = 93/130 (71%)
Query: 3 SGKEARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNK 62
SGK R++ +LV+ FF EL+SGY+ +S+AL++DSF+ML+D+ISL + L A +A+
Sbjct: 5 SGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLSAGYIARRP 64
Query: 63 NPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGL 122
TYG+ RAE++GAL NAVFL ALC +I +EA+ R +P+ I +P+LVLIVG GL
Sbjct: 65 TRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERIDDPELVLIVGVLGL 124
Query: 123 VSNFIGLALF 132
+ N +GL +F
Sbjct: 125 LVNVVGLLIF 134
>Hs14141726 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 507
Score = 122 bits (306), Expect = 1e-27
Identities = 58/125 (46%), Positives = 88/125 (70%)
Query: 8 RIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAK 67
R++ +L + F +E++ + SLA+++DSFHML+D+++LV+AL A A+ + K
Sbjct: 10 RLLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVALVAERFARRTHATQK 69
Query: 68 YTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSNFI 127
T+GW RAE++GALVNA+FL LC +IL+EAI+RF +P E+ P +VL VG GL+ N +
Sbjct: 70 NTFGWIRAEVMGALVNAIFLTGLCFAILLEAIERFIEPHEMQQPLVVLGVGVAGLLVNVL 129
Query: 128 GLALF 132
GL LF
Sbjct: 130 GLCLF 134
Score = 101 bits (251), Expect = 3e-21
Identities = 59/185 (31%), Positives = 89/185 (47%), Gaps = 37/185 (20%)
Query: 246 MNMHGVFLHVLGDALGNVGVIATAL---FIWKT----DFS-------------------- 278
+NM GVFLHVLGDALG+V V+ AL F WK DF
Sbjct: 243 LNMRGVFLHVLGDALGSVIVVVNALVFYFSWKGCSEGDFCVNPCFPDPCKAFVEIINSTH 302
Query: 279 ---------WRFYTDPAVXXXXXXXXXXXXXXXXXKASRILLQATPSNVSADDVKHDILS 329
W Y DP + +++ ILLQ P + ++ ++ +
Sbjct: 303 ASVYEAGPCWVLYLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQIDIRNLIKELRN 362
Query: 330 LPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEEFMNIAQVIRSIFHRYGIHSATVQPEF 389
+ GV VH+ H+W L S IA+VH++ + +P +M +A+ I+ +FH +GIH+ T+QPEF
Sbjct: 363 VEGVEEVHELHVWQLAGSRIIATVHIKCE-DPTSYMEVAKTIKDVFHNHGIHATTIQPEF 421
Query: 390 VGSGA 394
G+
Sbjct: 422 ASVGS 426
>Hs22041348 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 221
Score = 97.8 bits (242), Expect = 3e-20
Identities = 49/130 (37%), Positives = 79/130 (60%), Gaps = 1/130 (0%)
Query: 3 SGKEARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNK 62
SG+ R++ + V+ F +EL+ Y+ +SL+L +D+F +L+ +S++I + V A N
Sbjct: 5 SGRSFRLILMCVVSILLFVMELVIAYVGNSLSLASDAFAVLSHFVSMIIGFFGVR-ASNI 63
Query: 63 NPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGL 122
K TYG+ RA+++GA N +F +AL SIL+EAI+R+ PQ+ P LVL G GL
Sbjct: 64 KQHKKSTYGFLRADVVGAFGNTIFAVALMFSILVEAIKRYINPQKTEEPILVLSAGIIGL 123
Query: 123 VSNFIGLALF 132
N + +F
Sbjct: 124 FFNVLNYVIF 133
>At2g04620 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation diffusion
facilitator superfamily)
Length = 300
Score = 93.2 bits (230), Expect = 7e-19
Identities = 56/134 (41%), Positives = 87/134 (64%), Gaps = 5/134 (3%)
Query: 1 MLSGKEARIVTL-LVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVA 59
+LS K++R + L L+I+T + +E ++G+M +SL LI+D+ HML D +L I L+A ++
Sbjct: 18 ILSEKKSRKIALFLLINTAYMVVEFVAGFMSNSLGLISDACHMLFDCAALAIGLYASYIS 77
Query: 60 KNKNPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEI-TNPKLVLIVG 118
+ + +Y YG R E+L VNAVFL+ + I++E+I+R PQEI TN LV+ VG
Sbjct: 78 R-LPANHQYNYGRGRFEVLSGYVNAVFLVLVGALIVLESIERILDPQEISTNSLLVVSVG 136
Query: 119 CFGLVSNFIGLALF 132
GL+ N +GL F
Sbjct: 137 --GLLVNIVGLIFF 148
Score = 63.5 bits (153), Expect = 6e-10
Identities = 42/145 (28%), Positives = 67/145 (45%), Gaps = 6/145 (4%)
Query: 250 GVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXXXXKASRI 309
G+FLHVL D +G+VGV+ + L I + DPA ++ I
Sbjct: 160 GIFLHVLADTMGSVGVVISTLLI---KYKGWLVADPASSIFISILIIASVIPLLRNSAEI 216
Query: 310 LLQATPSNVSAD--DVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEEFMNI 367
LLQ P D + +IL GV S+ H+W+ T S +A++H+ + ++ ++
Sbjct: 217 LLQRVPRAHRQDLKEAMRNILKTKGVCSIQRLHVWSFTNSDVVATLHLLVSADSDKTDTK 276
Query: 368 AQVIRSIFHRYGIHSATVQPEFVGS 392
QV R + G+ T+Q E V S
Sbjct: 277 LQVSR-LLEDAGVKDWTLQVESVNS 300
>CE29581 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 561
Score = 90.9 bits (224), Expect = 3e-18
Identities = 42/128 (32%), Positives = 72/128 (55%), Gaps = 2/128 (1%)
Query: 2 LSGKEARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKN 61
+ G ++ + + F +E I+G + S+A++ADS+HM D+++L++A + +A
Sbjct: 106 VKGVSRSLIIQIGMTVIFCALEFITGVVCSSIAMLADSYHMAADVMALIVAFTCIKIATR 165
Query: 62 KNPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFG 121
P + YGW RAE LG N +F+ +CV + EA+ R IT+P VL++G G
Sbjct: 166 --PSTRLGYGWVRAETLGGFFNGIFMCTVCVLVFQEAVGRIINVHMITHPLQVLVIGFIG 223
Query: 122 LVSNFIGL 129
L+ N G+
Sbjct: 224 LLINLFGM 231
Score = 86.3 bits (212), Expect = 8e-17
Identities = 48/148 (32%), Positives = 76/148 (50%), Gaps = 4/148 (2%)
Query: 244 RSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRF--YTDPAVXXXXXXXXXXXXXX 301
+++N+HGV+LH+L DA G+V V+ +A F++ +W+ Y DP +
Sbjct: 381 KNVNIHGVWLHLLSDAFGSVIVMISAGFVYFLP-TWKIAAYLDPILSISLASIMGFTAVV 439
Query: 302 XXXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNP 361
+ LL+ TP + + VK D+ S+ GV V +W L IA+ HV I +P
Sbjct: 440 LVKTSGEKLLKQTPEGLDLEKVKKDLCSIVGVSKVEKLSVWTLCGQRIIAAAHVNI-CHP 498
Query: 362 EEFMNIAQVIRSIFHRYGIHSATVQPEF 389
F A I++ FH G+HS T++P F
Sbjct: 499 AVFPEAAYKIKNYFHDLGVHSTTIEPTF 526
>CE27065 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 519
Score = 90.9 bits (224), Expect = 3e-18
Identities = 42/128 (32%), Positives = 72/128 (55%), Gaps = 2/128 (1%)
Query: 2 LSGKEARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKN 61
+ G ++ + + F +E I+G + S+A++ADS+HM D+++L++A + +A
Sbjct: 64 VKGVSRSLIIQIGMTVIFCALEFITGVVCSSIAMLADSYHMAADVMALIVAFTCIKIATR 123
Query: 62 KNPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFG 121
P + YGW RAE LG N +F+ +CV + EA+ R IT+P VL++G G
Sbjct: 124 --PSTRLGYGWVRAETLGGFFNGIFMCTVCVLVFQEAVGRIINVHMITHPLQVLVIGFIG 181
Query: 122 LVSNFIGL 129
L+ N G+
Sbjct: 182 LLINLFGM 189
Score = 86.3 bits (212), Expect = 8e-17
Identities = 48/148 (32%), Positives = 76/148 (50%), Gaps = 4/148 (2%)
Query: 244 RSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRF--YTDPAVXXXXXXXXXXXXXX 301
+++N+HGV+LH+L DA G+V V+ +A F++ +W+ Y DP +
Sbjct: 339 KNVNIHGVWLHLLSDAFGSVIVMISAGFVYFLP-TWKIAAYLDPILSISLASIMGFTAVV 397
Query: 302 XXXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNP 361
+ LL+ TP + + VK D+ S+ GV V +W L IA+ HV I +P
Sbjct: 398 LVKTSGEKLLKQTPEGLDLEKVKKDLCSIVGVSKVEKLSVWTLCGQRIIAAAHVNI-CHP 456
Query: 362 EEFMNIAQVIRSIFHRYGIHSATVQPEF 389
F A I++ FH G+HS T++P F
Sbjct: 457 AVFPEAAYKIKNYFHDLGVHSTTIEPTF 484
>7299414 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation diffusion
facilitator superfamily)
Length = 366
Score = 87.0 bits (214), Expect = 5e-17
Identities = 46/120 (38%), Positives = 74/120 (61%), Gaps = 2/120 (1%)
Query: 13 LVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAKYTYGW 72
L+++ +F F+EL G + +SL LI+DSFHM D L+ L A + K K D K++YG+
Sbjct: 40 LLLNLSFAFVELFYGIVTNSLGLISDSFHMFFDCTGLLAGLAASVITKWKAND-KFSYGY 98
Query: 73 KRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSNFIGLALF 132
RAE+L VN++FL+ + IL E ++R +P E+ + +L +V GL+ N +G+ F
Sbjct: 99 VRAEVLAGFVNSLFLLFIAFFILSEGVERLIEPPEVKHERL-FVVSVLGLLVNLVGIYAF 157
Score = 64.7 bits (156), Expect = 3e-10
Identities = 41/148 (27%), Positives = 67/148 (44%), Gaps = 6/148 (4%)
Query: 245 SMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXXXX 304
S M GVFLH+L D LG+VGVI +A+ + F W DP
Sbjct: 223 SQIMRGVFLHILADTLGSVGVIISAVLMHM--FGW-MIADPICSIFIALLIALSVLSLIK 279
Query: 305 KASRILLQATPSNV--SADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPE 362
++ IL+Q P+++ S + L GV +V + H W L +Y+ ++ +E+ N +
Sbjct: 280 ESIMILMQRQPADLDRSLPQCYQKVTGLAGVYAVQEPHFWTLCSDVYVGALKLEVSKNVD 339
Query: 363 EFMNIAQVIRSIFHRYGIHSATVQPEFV 390
+ R IF G+ +Q ++V
Sbjct: 340 PKYVVTHT-RMIFEAVGVKQIYIQLDYV 366
>CE26955_2 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation diffusion
facilitator superfamily)
Length = 758
Score = 85.1 bits (209), Expect = 2e-16
Identities = 48/129 (37%), Positives = 73/129 (56%), Gaps = 2/129 (1%)
Query: 1 MLSGKEARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAK 60
+++ RI L ++ F +E + G+ +SL LI+D FHML D +LV+ L A +V
Sbjct: 318 LMNNDSRRIFWFLCVNLGFCGVEFLYGFWTNSLGLISDGFHMLFDCSALVMGLVA-SVMA 376
Query: 61 NKNPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCF 120
P +T+G+ R EIL +NA+FL + + ILIEA++R F P I +L L V
Sbjct: 377 RWPPTRHFTFGFGRVEILSGFINALFLCVIALFILIEALERLFDPPNINTDRL-LFVAIS 435
Query: 121 GLVSNFIGL 129
GL+ N G+
Sbjct: 436 GLIVNLFGM 444
>7298209 [P] KOG1482 Zn2+ transporter
Length = 472
Score = 84.3 bits (207), Expect = 3e-16
Identities = 87/391 (22%), Positives = 153/391 (38%), Gaps = 35/391 (8%)
Query: 8 RIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAK 67
+++ ++ F E++ G + +SLA+ D+ H+L D S +I+L+A+ +A + +
Sbjct: 90 KLIIASILCLVFMIAEIVGGVLSNSLAIATDAAHLLTDFASFMISLFAIWIA-GRPSTQR 148
Query: 68 YTYGWKRAEILGALVNAVFLIALCVSILI-EAIQRFFQPQEITNPKLVLIVGCFGLVSNF 126
++GW RAE++GA+ +VF+I + IL+ AI R N K++LI ++ N
Sbjct: 149 MSFGWYRAEVIGAMA-SVFMIWVITGILVWLAIGRLISGDYEVNAKIMLITSGLAILVNV 207
Query: 127 I-GLALFXXXXXXXXXXXXXXAPDLXXXXXXXXXXXXXXXXXXXXXXQTNGLDEGSDYEP 185
I G+ L + ++ G Y P
Sbjct: 208 IMGVQLQHGHSHGLGGGHG------HSHGGSKNASHVQATSTPCSDSPSQRIEGGVAYAP 261
Query: 186 ETIEDMMPHSIVERTFSPKST----PVXXXXXXXXXXXTGLLTEQHLNXXXXXXXXXXXX 241
E E +P + TFS ++T P T + H
Sbjct: 262 EDAE--LPGGGLP-TFSYQNTKLVDPTLDLEIAAVLAETAPGSHHH----------GGPV 308
Query: 242 XQRSMNMH--GVFLHVLGDALGNVGVIATALFIWKTDFSWRFYT--DPAVXXXXXXXXXX 297
+ ++NM+ +HV+GD + +VGV A I + W Y+ DP
Sbjct: 309 GREAVNMNVRAALIHVIGDVIQSVGVFVAAGVI----YFWPEYSIVDPICTFVFSIIVLF 364
Query: 298 XXXXXXXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEI 357
A +L++ TP+ + +V + GV VH+ IW L+ + S H+ I
Sbjct: 365 TTFTIMKDALLVLMEGTPNYMHYAEVLQIFQGIEGVERVHNLRIWALSINKVALSAHLAI 424
Query: 358 QSNPEEFMNIAQVIRSIFHRYGIHSATVQPE 388
N + ++ RY T+Q E
Sbjct: 425 AENANPKRILDAATSAVHLRYNFFETTIQIE 455
>Hs8922155 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 240
Score = 82.0 bits (201), Expect = 2e-15
Identities = 43/141 (30%), Positives = 74/141 (51%), Gaps = 7/141 (4%)
Query: 256 LGDALGNVGVIATALFIW------KTDFSWRFYTDPAVXXXXXXXXXXXXXXXXXKASRI 309
+GDALG+V V+ TA+ + + +W+ Y DP++ + + I
Sbjct: 1 MGDALGSVVVVITAIIFYVLPLKSEDPCNWQCYIDPSLTVLMVIIILSSAFPLIKETAAI 60
Query: 310 LLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEEFMNIAQ 369
LLQ P V+ +++ + ++PG+ SVH+ HIW L IA++H++ + + + +
Sbjct: 61 LLQMVPKGVNMEELMSKLSAVPGISSVHEVHIWELVSGKIIATLHIKYPKD-RGYQDAST 119
Query: 370 VIRSIFHRYGIHSATVQPEFV 390
IR IFH GIH+ T+Q E V
Sbjct: 120 KIREIFHHAGIHNVTIQFENV 140
>HsM4508043 [P] KOG1482 Zn2+ transporter
Length = 388
Score = 81.6 bits (200), Expect = 2e-15
Identities = 44/143 (30%), Positives = 73/143 (50%), Gaps = 4/143 (2%)
Query: 247 NMHGVFLHVLGDALGNVGVIATALFIW-KTDFSWRFYTDPAVXXXXXXXXXXXXXXXXXK 305
++ F+HVLGD L + GV+A ++ I+ K + DP
Sbjct: 231 SVRAAFVHVLGDLLQSFGVLAASILIYFKPQYK---AADPISTFLFSICALGSTAPTLRD 287
Query: 306 ASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEEFM 365
RIL++ TP NV + V+ +LS+PGV + H+ H+W LT + ++AS H+ I S +
Sbjct: 288 VLRILMEGTPRNVGFEPVRDTLLSVPGVRATHELHLWALTLTYHVASAHLAIDSTADPEA 347
Query: 366 NIAQVIRSIFHRYGIHSATVQPE 388
+A+ ++ R+G S T+Q E
Sbjct: 348 VLAEASSRLYSRFGFSSCTLQVE 370
Score = 52.0 bits (123), Expect = 2e-06
Identities = 29/105 (27%), Positives = 56/105 (52%), Gaps = 1/105 (0%)
Query: 23 ELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAKYTYGWKRAEILGALV 82
E++ GY+ HSLA++ D+ H+L D+ S++ +L+++ ++ + T+GW R+E LGAL
Sbjct: 90 EVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLS-TRPATRTMTFGWHRSETLGALA 148
Query: 83 NAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSNFI 127
+ V L + +L A R +L+ + +N +
Sbjct: 149 SVVSLWMVTGILLYLAFVRLLHSDYHIEGGAMLLTASIAVCANLL 193
>Hs21361112 [P] KOG1482 Zn2+ transporter
Length = 388
Score = 81.6 bits (200), Expect = 2e-15
Identities = 44/143 (30%), Positives = 73/143 (50%), Gaps = 4/143 (2%)
Query: 247 NMHGVFLHVLGDALGNVGVIATALFIW-KTDFSWRFYTDPAVXXXXXXXXXXXXXXXXXK 305
++ F+HVLGD L + GV+A ++ I+ K + DP
Sbjct: 231 SVRAAFVHVLGDLLQSFGVLAASILIYFKPQYK---AADPISTFLFSICALGSTAPTLRD 287
Query: 306 ASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEEFM 365
RIL++ TP NV + V+ +LS+PGV + H+ H+W LT + ++AS H+ I S +
Sbjct: 288 VLRILMEGTPRNVGFEPVRDTLLSVPGVRATHELHLWALTLTYHVASAHLAIDSTADPEA 347
Query: 366 NIAQVIRSIFHRYGIHSATVQPE 388
+A+ ++ R+G S T+Q E
Sbjct: 348 VLAEASSRLYSRFGFSSCTLQVE 370
Score = 52.0 bits (123), Expect = 2e-06
Identities = 29/105 (27%), Positives = 56/105 (52%), Gaps = 1/105 (0%)
Query: 23 ELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAKYTYGWKRAEILGALV 82
E++ GY+ HSLA++ D+ H+L D+ S++ +L+++ ++ + T+GW R+E LGAL
Sbjct: 90 EVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLS-TRPATRTMTFGWHRSETLGALA 148
Query: 83 NAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSNFI 127
+ V L + +L A R +L+ + +N +
Sbjct: 149 SVVSLWMVTGILLYLAFVRLLHSDYHIEGGAMLLTASIAVCANLL 193
>SPAC17D4.03c [P] KOG1484 Putative Zn2+ transporter MSC2 (cation diffusion
facilitator superfamily)
Length = 732
Score = 79.7 bits (195), Expect = 8e-15
Identities = 45/133 (33%), Positives = 78/133 (57%), Gaps = 3/133 (2%)
Query: 1 MLSGKEAR-IVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVA 59
+L+ KE+R I +++ ++ F+++I G +SL LI+D+ HM D I++++ L A +A
Sbjct: 341 VLADKESRSIFYFFLLNVSYMFVQVIYGLWTNSLGLISDAIHMAFDCIAILVGLVATTLA 400
Query: 60 KNKNPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGC 119
K A Y +G+ + E L N +FL+ + SI+ EA+ R F P ++ +L L+V
Sbjct: 401 KMPLNYA-YPFGFAKIEALSGFTNGIFLVLISFSIVGEALYRLFHPPQMNTDQL-LLVSF 458
Query: 120 FGLVSNFIGLALF 132
GLV N +G+ F
Sbjct: 459 LGLVVNLVGILAF 471
>Hs19424134 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation diffusion
facilitator superfamily)
Length = 376
Score = 79.3 bits (194), Expect = 1e-14
Identities = 48/133 (36%), Positives = 78/133 (58%), Gaps = 3/133 (2%)
Query: 1 MLSGKEAR-IVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVA 59
+LS K +R + L ++ +F F+EL+ G + L LI+DSFHM D +++ L A ++
Sbjct: 29 ILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVIS 88
Query: 60 KNKNPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGC 119
K + DA ++YG+ RAE+L VN +FLI I E ++R P ++ + +L L+V
Sbjct: 89 KWGDNDA-FSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERL-LLVSI 146
Query: 120 FGLVSNFIGLALF 132
G V N IG+ +F
Sbjct: 147 LGFVVNLIGIFVF 159
Score = 53.9 bits (128), Expect = 5e-07
Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 6/144 (4%)
Query: 248 MHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXXXXKAS 307
+ GVFLH+L D LG++GVIA+A+ + DP ++
Sbjct: 234 LQGVFLHILADTLGSIGVIASAIMMQNFGL---MIADPICSILIAILIVVSVIPLLRESV 290
Query: 308 RILLQATPSNV--SADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEEFM 365
IL+Q TP + S + L G S+ + H W L +Y+ ++ + + + +
Sbjct: 291 GILMQRTPPLLENSLPQCYQRVQQLQGAYSLQEQHFWTLCSDVYVGTLKLIVAPDADARW 350
Query: 366 NIAQVIRSIFHRYGIHSATVQPEF 389
++Q +IF + G+ VQ +F
Sbjct: 351 ILSQT-HNIFTQAGVRQLYVQIDF 373
>CE03664 [P] KOG1482 Zn2+ transporter
Length = 382
Score = 78.2 bits (191), Expect = 2e-14
Identities = 46/148 (31%), Positives = 70/148 (47%), Gaps = 2/148 (1%)
Query: 245 SMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXXXX 304
++N+ F+HVLGD L ++GV+ ALFI+ SW DP
Sbjct: 224 NINVRAAFIHVLGDLLQSLGVLVAALFIYFQP-SW-VIIDPICTLVFSVIVLCTTIYILR 281
Query: 305 KASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEEF 364
A +LL+ PSN+ V + + GV VHD IW+LT SVH+EI +N +
Sbjct: 282 DAMIVLLEGRPSNIDFAKVFSSLEDIEGVKKVHDLRIWSLTMDKIALSVHLEIDANSQSQ 341
Query: 365 MNIAQVIRSIFHRYGIHSATVQPEFVGS 392
+ + + + Y +H T+Q E G+
Sbjct: 342 SILRETRKMLKQTYNVHEITIQIEEFGA 369
Score = 69.3 bits (168), Expect = 1e-11
Identities = 43/129 (33%), Positives = 75/129 (57%), Gaps = 4/129 (3%)
Query: 5 KEARIVTLLVIDTTFFFI-ELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKN 63
+ RI+ L V+ FF + E+I G + SLA++ D+ H+L D S++I+L+++ +A+ +
Sbjct: 71 RATRILWLTVVLCLFFMVCEVIGGVLAGSLAIVTDAAHLLTDFASVLISLFSLYIAR-RP 129
Query: 64 PDAKYTYGWKRAEILGALVNAVFLIALCVSILIE-AIQRFFQPQEITNPKLVLIVGCFGL 122
P K ++G+ RAE+LGA +VFLI + +L+ AI R ++ + G+
Sbjct: 130 PSQKMSFGFHRAEVLGAFF-SVFLIWIVTGVLVVLAIMRIVSGDYEVEGGIMALTAALGV 188
Query: 123 VSNFIGLAL 131
V N + LAL
Sbjct: 189 VVNLVMLAL 197
>Hs20070323_2 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation diffusion
facilitator superfamily)
Length = 674
Score = 77.8 bits (190), Expect = 3e-14
Identities = 43/125 (34%), Positives = 72/125 (57%), Gaps = 2/125 (1%)
Query: 8 RIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAK 67
+I L ++ F F+EL G + +SL LI+D FHML D +LV+ L+A +++ K
Sbjct: 327 QIFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWK-ATRI 385
Query: 68 YTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSNFI 127
++YG+ R EIL +N +FLI + + +E++ R P E+ + ++ V GL+ N I
Sbjct: 386 FSYGYGRIEILSGFINGLFLIVIAFFVFMESVARLIDPPEL-DTHMLTPVSVGGLIVNLI 444
Query: 128 GLALF 132
G+ F
Sbjct: 445 GICAF 449
Score = 66.2 bits (160), Expect = 9e-11
Identities = 42/144 (29%), Positives = 65/144 (44%), Gaps = 6/144 (4%)
Query: 247 NMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXXXXKA 306
NM GVFLHVL D LG++GVI + + I F W F DP A
Sbjct: 497 NMRGVFLHVLADTLGSIGVIVSTVLI--EQFGW-FIADPLCSLFIAILIFLSVVPLIKDA 553
Query: 307 SRILLQATPSNVSAD--DVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEEF 364
++LL P + I + G++S D H W + S+ ++H+++ S+ E
Sbjct: 554 CQVLLLRLPPEYEKELHIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQVTSDVLE- 612
Query: 365 MNIAQVIRSIFHRYGIHSATVQPE 388
I Q + I G+++ T+Q E
Sbjct: 613 QRIVQQVTGILKDAGVNNLTIQVE 636
>CE16617 [P] KOG1482 Zn2+ transporter
Length = 410
Score = 76.6 bits (187), Expect = 7e-14
Identities = 43/145 (29%), Positives = 71/145 (48%), Gaps = 3/145 (2%)
Query: 244 RSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXXX 303
+++N+ +HV+GD + ++GV+ AL I T ++ DP
Sbjct: 251 KNVNVRAALIHVIGDLVQSIGVLIAALIIRFTGWT---LADPICTFLFSIIVLFTTVTVM 307
Query: 304 XKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEE 363
+L++ATPS+ DVK + +L GV VHD H+W++ SVH+ ++S
Sbjct: 308 RDIFFVLMEATPSHYDLSDVKKALSALEGVKGVHDLHLWSIGMDKTAFSVHLALESPNRA 367
Query: 364 FMNIAQVIRSIFHRYGIHSATVQPE 388
N+A+ I R+G+ ATVQ E
Sbjct: 368 MENVAEARSLIRRRFGVAVATVQVE 392
Score = 70.9 bits (172), Expect = 4e-12
Identities = 36/118 (30%), Positives = 69/118 (57%), Gaps = 2/118 (1%)
Query: 15 IDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAKYTYGWKR 74
+ F E + G+ SLA++ D+ HML+D++S +I+++A+ A+ + ++G++R
Sbjct: 111 LSAVFIAAEFVGGFWAQSLAIMTDAGHMLSDLLSFIISIFAIRCAR-LPASKRLSFGYER 169
Query: 75 AEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSNFI-GLAL 131
AE+LGAL + + L L +++ AIQR + + ++LI G++ N + GL L
Sbjct: 170 AEVLGALTSVIILWVLTTVLVVVAIQRIVNNEHEVDADVMLITAGVGVLFNIVMGLVL 227
>CE16616 [P] KOG1482 Zn2+ transporter
Length = 391
Score = 76.6 bits (187), Expect = 7e-14
Identities = 43/145 (29%), Positives = 71/145 (48%), Gaps = 3/145 (2%)
Query: 244 RSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXXX 303
+++N+ +HV+GD + ++GV+ AL I T ++ DP
Sbjct: 232 KNVNVRAALIHVIGDLVQSIGVLIAALIIRFTGWT---LADPICTFLFSIIVLFTTVTVM 288
Query: 304 XKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEE 363
+L++ATPS+ DVK + +L GV VHD H+W++ SVH+ ++S
Sbjct: 289 RDIFFVLMEATPSHYDLSDVKKALSALEGVKGVHDLHLWSIGMDKTAFSVHLALESPNRA 348
Query: 364 FMNIAQVIRSIFHRYGIHSATVQPE 388
N+A+ I R+G+ ATVQ E
Sbjct: 349 MENVAEARSLIRRRFGVAVATVQVE 373
Score = 71.2 bits (173), Expect = 3e-12
Identities = 40/132 (30%), Positives = 75/132 (56%), Gaps = 4/132 (3%)
Query: 3 SGKEARIVTLLV--IDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAK 60
+G+ A V V + F E + G+ SLA++ D+ HML+D++S +I+++A+ A+
Sbjct: 78 TGRRAEKVLWAVAALSAVFIAAEFVGGFWAQSLAIMTDAGHMLSDLLSFIISIFAIRCAR 137
Query: 61 NKNPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCF 120
+ ++G++RAE+LGAL + + L L +++ AIQR + + ++LI
Sbjct: 138 -LPASKRLSFGYERAEVLGALTSVIILWVLTTVLVVVAIQRIVNNEHEVDADVMLITAGV 196
Query: 121 GLVSNFI-GLAL 131
G++ N + GL L
Sbjct: 197 GVLFNIVMGLVL 208
>YDR205w [P] KOG1484 Putative Zn2+ transporter MSC2 (cation diffusion
facilitator superfamily)
Length = 740
Score = 75.5 bits (184), Expect = 1e-13
Identities = 44/133 (33%), Positives = 69/133 (51%), Gaps = 2/133 (1%)
Query: 1 MLSGKEAR-IVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVA 59
M K+ R I + L+++T F F++L+ + SL L++DS HM D SL++ L A +
Sbjct: 395 MALNKDTRSIFSFLLLNTAFMFVQLLYSFRSKSLGLLSDSLHMALDCTSLLLGLIAGVLT 454
Query: 60 KNKNPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGC 119
K D K+ +G L N V L+ + I +EAI+R F P + +L+V
Sbjct: 455 KKPASD-KFPFGLNYLGTLAGFTNGVLLLGIVCGIFVEAIERIFNPIHLHATNELLVVAT 513
Query: 120 FGLVSNFIGLALF 132
GL+ N +GL F
Sbjct: 514 LGLLVNLVGLFAF 526
>HsM7019533 [P] KOG1482 Zn2+ transporter
Length = 429
Score = 75.5 bits (184), Expect = 1e-13
Identities = 38/122 (31%), Positives = 72/122 (58%), Gaps = 1/122 (0%)
Query: 6 EARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPD 65
+AR+ V+ F EL+ GY+ +SLA++ D+ HML D+ ++++ L A+ ++ +K+P
Sbjct: 111 KARLTIAAVLYLLFMIGELVGGYIANSLAIMTDALHMLTDLSAIILTLLALWLS-SKSPT 169
Query: 66 AKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSN 125
++T+G+ R E+L A+++ + + L +L EA+QR N ++LI G+ N
Sbjct: 170 KRFTFGFHRLEVLSAMISVLLVYILMGFLLYEAVQRTIHMNYEINGDIMLITAAVGVAVN 229
Query: 126 FI 127
I
Sbjct: 230 VI 231
Score = 58.9 bits (141), Expect = 1e-08
Identities = 39/149 (26%), Positives = 70/149 (46%), Gaps = 10/149 (6%)
Query: 243 QRSMNMHGVFLHVLGDALGNVGVIATALFI-WKTDFSWRFYTDPAVXXXXXXXXXXXXXX 301
Q S+ + F+H LGD + +VGV+ A I +K ++ DP
Sbjct: 266 QDSLAVRAAFVHALGDLVQSVGVLIAAYIIRFKPEYK---IADPICTYVFSLLVAFTTFR 322
Query: 302 XXXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEI---- 357
I+L+ PS+++ D +K ++ + V SV D +IW+LT A VH+++
Sbjct: 323 IIWDTVVIILEGVPSHLNVDYIKEALMKIEDVYSVEDLNIWSLTSGKSTAIVHIQLIPGS 382
Query: 358 QSNPEEFMNIAQVIRSIFHRYGIHSATVQ 386
S EE + A + + + +G++ T+Q
Sbjct: 383 SSKWEEVQSKANHL--LLNTFGMYRCTIQ 409
>Hs21359890 [P] KOG1482 Zn2+ transporter
Length = 429
Score = 75.5 bits (184), Expect = 1e-13
Identities = 38/122 (31%), Positives = 72/122 (58%), Gaps = 1/122 (0%)
Query: 6 EARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPD 65
+AR+ V+ F EL+ GY+ +SLA++ D+ HML D+ ++++ L A+ ++ +K+P
Sbjct: 111 KARLTIAAVLYLLFMIGELVGGYIANSLAIMTDALHMLTDLSAIILTLLALWLS-SKSPT 169
Query: 66 AKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSN 125
++T+G+ R E+L A+++ + + L +L EA+QR N ++LI G+ N
Sbjct: 170 KRFTFGFHRLEVLSAMISVLLVYILMGFLLYEAVQRTIHMNYEINGDIMLITAAVGVAVN 229
Query: 126 FI 127
I
Sbjct: 230 VI 231
Score = 58.9 bits (141), Expect = 1e-08
Identities = 39/149 (26%), Positives = 70/149 (46%), Gaps = 10/149 (6%)
Query: 243 QRSMNMHGVFLHVLGDALGNVGVIATALFI-WKTDFSWRFYTDPAVXXXXXXXXXXXXXX 301
Q S+ + F+H LGD + +VGV+ A I +K ++ DP
Sbjct: 266 QDSLAVRAAFVHALGDLVQSVGVLIAAYIIRFKPEYK---IADPICTYVFSLLVAFTTFR 322
Query: 302 XXXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEI---- 357
I+L+ PS+++ D +K ++ + V SV D +IW+LT A VH+++
Sbjct: 323 IIWDTVVIILEGVPSHLNVDYIKEALMKIEDVYSVEDLNIWSLTSGKSTAIVHIQLIPGS 382
Query: 358 QSNPEEFMNIAQVIRSIFHRYGIHSATVQ 386
S EE + A + + + +G++ T+Q
Sbjct: 383 SSKWEEVQSKANHL--LLNTFGMYRCTIQ 409
>At2g46800 [P] KOG1482 Zn2+ transporter
Length = 398
Score = 74.7 bits (182), Expect = 3e-13
Identities = 41/146 (28%), Positives = 70/146 (47%), Gaps = 2/146 (1%)
Query: 243 QRSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXX 302
+R++N+ G +LHVLGD++ +VGV+ IW W+ D
Sbjct: 254 KRNINLQGAYLHVLGDSIQSVGVMIGGAIIWYNP-EWKI-VDLICTLAFSVIVLGTTINM 311
Query: 303 XXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPE 362
+L+++TP + A ++ +L + VV+VH+ HIW +T + + HV I+ +
Sbjct: 312 IRNILEVLMESTPREIDATKLEKGLLEMEEVVAVHELHIWAITVGKVLLACHVNIRPEAD 371
Query: 363 EFMNIAQVIRSIFHRYGIHSATVQPE 388
M + +VI I Y I T+Q E
Sbjct: 372 ADMVLNKVIDYIRREYNISHVTIQIE 397
Score = 66.6 bits (161), Expect = 7e-11
Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 1/125 (0%)
Query: 3 SGKEARIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNK 62
S ++ +V+ F +E++ G +SLA++ D+ H+L+D+ + I+L+++ A
Sbjct: 52 SASMRKLCIAVVLCLVFMSVEVVGGIKANSLAILTDAAHLLSDVAAFAISLFSLWAA-GW 110
Query: 63 NPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGL 122
+ TYG+ R EILGALV+ + L ++ EAI R N L+ +V FGL
Sbjct: 111 EATPRQTYGFFRIEILGALVSIQLIWLLTGILVYEAIIRIVTETSEVNGFLMFLVAAFGL 170
Query: 123 VSNFI 127
V N I
Sbjct: 171 VVNII 175
>7296322 [P] KOG1483 Zn2+ transporter ZNT1 and related Cd2+/Zn2+
transporters (cation diffusion facilitator superfamily)
Length = 513
Score = 72.4 bits (176), Expect = 1e-12
Identities = 39/143 (27%), Positives = 70/143 (48%), Gaps = 4/143 (2%)
Query: 253 LHVLGDALGNVGVIATALFIWKTDFSWRF--YTDPAVXXXXXXXXXXXXXXXXXKASRIL 310
+ +L D + VI A ++ + + DP + ++ IL
Sbjct: 246 VEMLRDVSSTIFVIVCAAIVYVAEDEQHTAKFIDPVLSIFSCVLLVTLSYPYMKESCLIL 305
Query: 311 LQATPSNVSADDVKHDILS-LPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEEFMNIAQ 369
LQ P ++ + + +++ P ++S HD HIW L Y+A++H++ Q NP+ ++ I +
Sbjct: 306 LQTIPGSIDLEIFERTLVTKFPEIISYHDLHIWQLAAHRYVATIHIQFQ-NPKLYLKIIE 364
Query: 370 VIRSIFHRYGIHSATVQPEFVGS 392
+RS FH GI + T+QPEF S
Sbjct: 365 QVRSYFHDQGIGAVTIQPEFYPS 387
>At3g61940 [P] KOG1482 Zn2+ transporter
Length = 334
Score = 70.1 bits (170), Expect = 6e-12
Identities = 39/145 (26%), Positives = 69/145 (46%), Gaps = 2/145 (1%)
Query: 244 RSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXXX 303
R++N+ G +LHVLGD + ++GV+ IW W+ D
Sbjct: 191 RNINVQGAYLHVLGDLIQSIGVMIGGGMIWYNP-KWKVI-DLICTLFFSVIVLGTTIKML 248
Query: 304 XKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPEE 363
+L+++TP + A ++ ++ + VV VH+ HIW +T + S HV+++ +
Sbjct: 249 RSILEVLMESTPREIDARQLEKGLMEIEEVVDVHELHIWAITVGKALFSCHVKVRPEAGD 308
Query: 364 FMNIAQVIRSIFHRYGIHSATVQPE 388
M + +VI I+ Y I T+Q E
Sbjct: 309 EMVLNKVIDYIWREYRISHVTIQIE 333
Score = 59.3 bits (142), Expect = 1e-08
Identities = 39/124 (31%), Positives = 68/124 (54%), Gaps = 8/124 (6%)
Query: 8 RIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVI---ALWAVNVAKNKNP 64
++ ++V+ F IE++ G +SLA++AD+ H+L D+ + I +LWA + N
Sbjct: 32 KLCFVVVLCLLFMSIEVVCGIKANSLAILADAAHLLTDVGAFAISMLSLWASSWEAN--- 88
Query: 65 DAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQ-PQEITNPKLVLIVGCFGLV 123
+ +YG+ R EILG LV+ + L ++ EA+ R Q + + +++V FGLV
Sbjct: 89 -PRQSYGFFRIEILGTLVSIQLIWLLTGILVYEAVTRLVQETNDDVDGFFMVLVAAFGLV 147
Query: 124 SNFI 127
N I
Sbjct: 148 VNII 151
>At3g58810 [P] KOG1482 Zn2+ transporter
Length = 378
Score = 69.7 bits (169), Expect = 8e-12
Identities = 39/146 (26%), Positives = 69/146 (46%), Gaps = 2/146 (1%)
Query: 243 QRSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXX 302
QR++N+ G +LHVLGD++ +VGV+ IW W+ D
Sbjct: 233 QRNVNIQGAYLHVLGDSIQSVGVMIGGAIIWYKP-EWKIL-DLICTLVFSVIVLGTTIGM 290
Query: 303 XXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPE 362
+L+++TP + ++ + + VV+VH+ HIW +T + + HV+I+ E
Sbjct: 291 LRNILEVLMESTPREIDPTMLEKGVCEIEEVVAVHELHIWAITVGKLLLACHVKIRPEAE 350
Query: 363 EFMNIAQVIRSIFHRYGIHSATVQPE 388
M + ++I I + I T+Q E
Sbjct: 351 ADMVLDKIIDYIKREHNISHVTIQIE 376
Score = 57.4 bits (137), Expect = 4e-08
Identities = 33/118 (27%), Positives = 64/118 (53%), Gaps = 1/118 (0%)
Query: 8 RIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAK 67
+++ +++ F +E++ G +SLA++ D+ H+L+D+ + I+L+++ A + +
Sbjct: 58 KLLIAVLLCAIFIVVEVVGGIKANSLAILTDAAHLLSDVAAFAISLFSL-WASGWKANPQ 116
Query: 68 YTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSN 125
+YG+ R EILGALV+ + L ++ EAI R L+ V GL+ N
Sbjct: 117 QSYGFFRIEILGALVSIQMIWLLAGILVYEAIVRLNNGSGEVEGSLMFAVSAVGLLVN 174
>7297930_2 [P] KOG1482 Zn2+ transporter
Length = 371
Score = 69.7 bits (169), Expect = 8e-12
Identities = 38/125 (30%), Positives = 73/125 (58%), Gaps = 3/125 (2%)
Query: 5 KEARIVTLL--VIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNK 62
K AR V ++ ++ T F +E+I G + +SLA+ D+ H+L D+ S +I++ A+++A
Sbjct: 13 KAARRVLIIACILCTIFLILEVIGGILSNSLAIATDAAHLLTDLASFLISISALHLAGRP 72
Query: 63 NPDAKYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGL 122
+ + + YGW RAE++GA+V+ F+ + ++ AI R+ + K++LI +
Sbjct: 73 SSE-RLNYGWHRAEVIGAMVSIFFIWVVTGILVYMAIMRWVNQDFELDAKIMLITSALAI 131
Query: 123 VSNFI 127
+ N I
Sbjct: 132 LFNVI 136
Score = 58.9 bits (141), Expect = 1e-08
Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 6/151 (3%)
Query: 245 SMNMHGVFLHVLGDALGNVGVIATAL--FIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXX 302
++N+ +HV+GD + + GV AL F W W F D
Sbjct: 186 NINVRAAIIHVVGDIIQSFGVFVAALIIFFWP---EWAFM-DSVCTFVFSVLVLVVTFKI 241
Query: 303 XXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPE 362
+L++ATP + ++VK LS+ GV VH+ IW L+ + S H+ I + +
Sbjct: 242 LRDVLMVLMEATPDFMDYEEVKQTFLSISGVEHVHNLRIWALSINKVALSAHLAISKDAD 301
Query: 363 EFMNIAQVIRSIFHRYGIHSATVQPEFVGSG 393
+ + + I R+ T+Q E G
Sbjct: 302 PQLILEEATTLIHKRFKFFETTIQIEEYSPG 332
>Hs20540985 [P] KOG1482 Zn2+ transporter
Length = 320
Score = 69.3 bits (168), Expect = 1e-11
Identities = 39/147 (26%), Positives = 73/147 (49%), Gaps = 4/147 (2%)
Query: 243 QRSMNMHGVFLHVLGDALGNVGVIATALFIW-KTDFSWRFYTDPAVXXXXXXXXXXXXXX 301
Q + ++ F+H LGD ++ V+ +AL I+ K ++ DP
Sbjct: 160 QANASVRAAFVHALGDLFQSISVLISALIIYFKPEYK---IADPICTFIFSILVLASTIT 216
Query: 302 XXXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNP 361
S +L++ P +++ VK IL++ GV+SVH HIW+LT + I S HV ++
Sbjct: 217 ILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILSAHVATAASR 276
Query: 362 EEFMNIAQVIRSIFHRYGIHSATVQPE 388
+ + ++ +++ + +HS T+Q E
Sbjct: 277 DSQVVRREIAKALSKSFTMHSLTIQME 303
Score = 63.5 bits (153), Expect = 6e-10
Identities = 31/109 (28%), Positives = 65/109 (59%), Gaps = 1/109 (0%)
Query: 19 FFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAKYTYGWKRAEIL 78
F E++ G++ SLA++ D+ H+L D+ S +++L+++ ++ +K P + T+GW RAEIL
Sbjct: 35 FMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFLLSLFSLWLS-SKPPSKRLTFGWHRAEIL 93
Query: 79 GALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSNFI 127
GAL++ + + + ++ A +R P +++IV + +N +
Sbjct: 94 GALLSILCIWVVTGVLVYLACERLLYPDYQIQATVMIIVSSCAVAANIV 142
>7302213 [P] KOG1482 Zn2+ transporter
Length = 452
Score = 68.6 bits (166), Expect = 2e-11
Identities = 33/106 (31%), Positives = 64/106 (60%), Gaps = 1/106 (0%)
Query: 22 IELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAKYTYGWKRAEILGAL 81
IE + GY+ SLA++ D+ H+ +D IS VI L A+ + + PD + ++G+KR E++GAL
Sbjct: 100 IEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIG-GRPPDERMSFGYKRFEVIGAL 158
Query: 82 VNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSNFI 127
+ + + + +++ AI+R F N +++++ G+V N +
Sbjct: 159 ASILGIWFVTTLLVVVAIERIFSQDFELNADMMMLISGIGIVINIV 204
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/147 (23%), Positives = 66/147 (44%), Gaps = 5/147 (3%)
Query: 244 RSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXXX 303
+++N+ +HV+GD + ++GV A+ I + Y DP
Sbjct: 305 KNLNLRAAMIHVIGDLVQSIGVFLAAVLIKVCPGAK--YADPLCTLIFSIIVIMTTLRLF 362
Query: 304 XKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNPE- 362
++ I++ A P N++ + ++ S+ GV S+H ++W T + VH+ S +
Sbjct: 363 RESLGIIVNAVPQNLNMRTLHLELGSIEGVRSLHHLNVWQQTSQQRVLMVHLVTDSRADG 422
Query: 363 -EFMNIAQVIRSIFHRYGIHSATVQPE 388
E + A + S RY I +T+Q E
Sbjct: 423 NEVLQAATALVS-SPRYNIKHSTIQLE 448
>Hs22041687 [P] KOG1484 Putative Zn2+ transporter MSC2 (cation diffusion
facilitator superfamily)
Length = 230
Score = 67.4 bits (163), Expect = 4e-11
Identities = 38/100 (38%), Positives = 60/100 (60%), Gaps = 2/100 (2%)
Query: 33 LALIADSFHMLNDIISLVIALWAVNVAKNKNPDAKYTYGWKRAEILGALVNAVFLIALCV 92
L LI+DSFHM D +++ L A ++K ++ DA ++YG+ RAE+L VN +FLI
Sbjct: 45 LGLISDSFHMFFDSTAILAGLAASVISKWRDNDA-FSYGYVRAEVLAGFVNGLFLIFTAF 103
Query: 93 SILIEAIQRFFQPQEITNPKLVLIVGCFGLVSNFIGLALF 132
I E ++R P ++ + +L L+V G V N IG+ +F
Sbjct: 104 FIFSEGVERALAPPDVHHERL-LLVSILGFVVNLIGIFVF 142
>ECU11g1510 [P] KOG1482 Zn2+ transporter
Length = 334
Score = 65.5 bits (158), Expect = 2e-10
Identities = 37/115 (32%), Positives = 68/115 (58%), Gaps = 3/115 (2%)
Query: 8 RIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAK 67
+I +L+I F F+EL + +SL+L+ADS H+L DI +++L +++ AK K + +
Sbjct: 23 KISKVLLIILMFMFLELWGHWKTNSLSLLADSLHLLVDIFGFIVSLLSLSWAK-KPSNKR 81
Query: 68 YTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKL--VLIVGCF 120
T+G+ R EI+G++V+ + A ++IE+ ++ P EI + +VG F
Sbjct: 82 MTFGYHRIEIIGSMVSIGLIWAAVGYLVIESFHKYLHPAEIDGGMFFGIAVVGFF 136
>Hs14210520 [P] KOG1482 Zn2+ transporter
Length = 323
Score = 65.1 bits (157), Expect = 2e-10
Identities = 36/147 (24%), Positives = 68/147 (45%), Gaps = 4/147 (2%)
Query: 243 QRSMNMHGVFLHVLGDALGNVGVIATALFIW-KTDFSWRFYTDPAVXXXXXXXXXXXXXX 301
+ + ++ F+HV+GD + ++GV+ A ++ K ++ Y DP
Sbjct: 163 EENPSVRAAFIHVIGDFMQSMGVLVAAYILYFKPEYK---YVDPICTFVFSILVLGTTLT 219
Query: 302 XXXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHVEIQSNP 361
+L++ TP V V+ +LS+ GV ++H HIW LT + + SVH+ I N
Sbjct: 220 ILRDVILVLMEGTPKGVDFTAVRDLLLSVEGVEALHSLHIWALTVAQPVLSVHIAIAQNT 279
Query: 362 EEFMNIAQVIRSIFHRYGIHSATVQPE 388
+ + + ++ H+ T+Q E
Sbjct: 280 DAQAVLKTASSRLQGKFHFHTVTIQIE 306
>At2g29410 [P] KOG1482 Zn2+ transporter
Length = 385
Score = 62.4 bits (150), Expect = 1e-09
Identities = 32/121 (26%), Positives = 67/121 (54%), Gaps = 3/121 (2%)
Query: 8 RIVTLLVIDTTFFFIELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAK-NKNPDA 66
R+ +L+ + ++++ G+ +SLA++ D+ H+L+D+ L ++L A+ V+ NP
Sbjct: 67 RLSSLIFLYLIVMSVQIVGGFKANSLAVMTDAAHLLSDVAGLCVSLLAIKVSSWEANP-- 124
Query: 67 KYTYGWKRAEILGALVNAVFLIALCVSILIEAIQRFFQPQEITNPKLVLIVGCFGLVSNF 126
+ ++G+KR E+L A ++ + + I+ EAIQR N +++ + FG N
Sbjct: 125 RNSFGFKRLEVLAAFLSVQLIWLVSGVIIHEAIQRLLSRSREVNGEIMFGISAFGFFMNL 184
Query: 127 I 127
+
Sbjct: 185 V 185
Score = 53.1 bits (126), Expect = 8e-07
Identities = 36/148 (24%), Positives = 64/148 (42%), Gaps = 6/148 (4%)
Query: 243 QRSMNMHGVFLHVLGDALGNVGVIATALFIWKTDFSWRFYTDPAVXXXXXXXXXXXXXXX 302
+ ++N+ G +LH + D + ++GV+ IW W D
Sbjct: 240 EMNINIQGAYLHAMADMIQSLGVMIGGGIIWVKP-KW-VLVDLICTLVFSAFALAATLPI 297
Query: 303 XXKASRILLQATPSNVSADDVKHDILSLPGVVSVHDFHIWNLTESLYIASVHV--EIQSN 360
IL++ P ++ + ++ + + GV V+D H+W +T + S H+ E ++
Sbjct: 298 LKNIFGILMERVPRDMDIEKLERGLKRIDGVKIVYDLHVWEITVGRIVLSCHILPEPGAS 357
Query: 361 PEEFMNIAQVIRSIFHRYGIHSATVQPE 388
P+E I V YGI+ ATVQ E
Sbjct: 358 PKEI--ITGVRNFCRKSYGIYHATVQVE 383
>YPL224c [P] KOG1485 Mitochondrial Fe2+ transporter MMT1 and related
transporters (cation diffusion facilitator superfamily)
Length = 449
Score = 51.6 bits (122), Expect = 2e-06
Identities = 26/72 (36%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 23 ELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAKYTYGWKRAEILGALV 82
+ + G HS AL+ADS H L+D++S + L++V A K P ++Y YG+ + E +G+L
Sbjct: 147 KFVGGITFHSQALLADSVHALSDLVSDFLTLFSVQYASRK-PTSEYPYGYGKVETVGSLA 205
Query: 83 NAVFLIALCVSI 94
+ L +SI
Sbjct: 206 VSTILAMAGISI 217
>YMR177w [P] KOG1485 Mitochondrial Fe2+ transporter MMT1 and related
transporters (cation diffusion facilitator superfamily)
Length = 510
Score = 50.8 bits (120), Expect = 4e-06
Identities = 26/72 (36%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 23 ELISGYMVHSLALIADSFHMLNDIISLVIALWAVNVAKNKNPDAKYTYGWKRAEILGALV 82
+ G + HS AL AD+ H ++D++S ++ L +V +A NK P A Y YG+ + E +G+L
Sbjct: 178 KFFGGIVFHSQALFADAIHAISDMVSDLLTLLSVGLAANK-PTADYPYGYGKIETVGSLA 236
Query: 83 NAVFLIALCVSI 94
+ L +SI
Sbjct: 237 VSTILAMAGISI 248
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.138 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,384,584
Number of Sequences: 60738
Number of extensions: 670745
Number of successful extensions: 1563
Number of sequences better than 1.0e-05: 38
Number of HSP's better than 0.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1442
Number of HSP's gapped (non-prelim): 73
length of query: 436
length of database: 30,389,216
effective HSP length: 109
effective length of query: 327
effective length of database: 23,768,774
effective search space: 7772389098
effective search space used: 7772389098
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)