ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2308 check: MH R KOG0594 General function prediction only Protein kinase PCTAIRE and related kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2308 825217 826179 321
(321 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFL029c [R] KOG0594 Protein kinase PCTAIRE and related kinases 162 6e-40
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 104 1e-22
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 102 1e-21
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 2e-21
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 100 5e-21
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 99 8e-21
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 96 5e-20
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 95 2e-19
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 95 2e-19
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 91 2e-18
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 89 1e-17
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 88 2e-17
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 3e-17
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 3e-17
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 4e-17
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 86 7e-17
CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 86 7e-17
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 86 7e-17
At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 86 7e-17
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 85 1e-16
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 85 1e-16
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 85 1e-16
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 85 2e-16
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 84 2e-16
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 84 2e-16
7298087 [T] KOG0660 Mitogen-activated protein kinase 84 2e-16
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 84 3e-16
At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases 84 3e-16
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 84 4e-16
SPAC1D4.06c [R] KOG0594 Protein kinase PCTAIRE and related kinases 83 6e-16
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 83 6e-16
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 83 6e-16
At2g46070 [T] KOG0660 Mitogen-activated protein kinase 82 8e-16
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 82 1e-15
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 82 1e-15
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 81 2e-15
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 81 2e-15
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 81 2e-15
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 81 2e-15
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 80 3e-15
7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 80 3e-15
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 79 7e-15
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 79 1e-14
At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases 79 1e-14
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 78 2e-14
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 78 2e-14
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 78 2e-14
7296451 [D] KOG0600 Cdc2-related protein kinase 78 2e-14
Hs7706549 [D] KOG0600 Cdc2-related protein kinase 78 2e-14
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 78 2e-14
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 78 2e-14
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 78 2e-14
At4g01370 [T] KOG0660 Mitogen-activated protein kinase 78 2e-14
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 78 2e-14
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 77 3e-14
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 77 3e-14
CE26422 [D] KOG0600 Cdc2-related protein kinase 77 3e-14
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 77 3e-14
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 77 3e-14
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 77 3e-14
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 77 3e-14
CE06686 [T] KOG0660 Mitogen-activated protein kinase 77 3e-14
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 77 4e-14
At5g64960 [D] KOG0600 Cdc2-related protein kinase 77 4e-14
7301110 [T] KOG0660 Mitogen-activated protein kinase 77 4e-14
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 77 4e-14
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 76 6e-14
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 76 6e-14
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 76 6e-14
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 76 6e-14
7290342 [G] KOG0658 Glycogen synthase kinase-3 76 6e-14
SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8 76 7e-14
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 76 7e-14
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 76 7e-14
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 75 1e-13
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 75 1e-13
At5g10270 [D] KOG0600 Cdc2-related protein kinase 75 1e-13
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 75 1e-13
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 75 1e-13
At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 1e-13
YKL139w [D] KOG0600 Cdc2-related protein kinase 75 2e-13
At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases 75 2e-13
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 2e-13
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 2e-13
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 74 2e-13
Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 2e-13
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 74 2e-13
Hs14110390 [D] KOG0600 Cdc2-related protein kinase 74 3e-13
Hs14110387 [D] KOG0600 Cdc2-related protein kinase 74 3e-13
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 3e-13
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 74 4e-13
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 74 4e-13
Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 4e-13
Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 4e-13
Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 4e-13
Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 4e-13
Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 4e-13
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 74 4e-13
CE21401 [G] KOG0658 Glycogen synthase kinase-3 74 4e-13
At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases 74 4e-13
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 74 4e-13
YLR113w [T] KOG0660 Mitogen-activated protein kinase 73 5e-13
SPBC36B7.09 [J] KOG1035 eIF-2alpha kinase GCN2 73 5e-13
Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases 73 5e-13
Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases 73 5e-13
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 73 6e-13
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 73 6e-13
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 73 6e-13
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 72 8e-13
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 72 8e-13
Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 8e-13
Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 8e-13
Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 8e-13
Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 8e-13
Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 8e-13
Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 8e-13
Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 8e-13
Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 8e-13
Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 8e-13
Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases 72 8e-13
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 72 8e-13
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 72 8e-13
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 8e-13
YCL024w [T] KOG0583 Serine/threonine protein kinase 72 1e-12
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 72 1e-12
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 72 1e-12
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 72 1e-12
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 72 1e-12
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 72 1e-12
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 71 2e-12
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 71 2e-12
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 71 2e-12
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 71 2e-12
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 71 2e-12
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 71 2e-12
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 71 2e-12
CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 71 2e-12
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 71 2e-12
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 71 2e-12
YNL307c [G] KOG0658 Glycogen synthase kinase-3 70 3e-12
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 3e-12
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 70 3e-12
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 3e-12
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 3e-12
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 70 3e-12
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 70 3e-12
CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 70 3e-12
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 70 3e-12
CE00847 [T] KOG0583 Serine/threonine protein kinase 70 3e-12
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 70 3e-12
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 70 4e-12
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 4e-12
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 4e-12
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 70 4e-12
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 70 4e-12
YDR283c [J] KOG1035 eIF-2alpha kinase GCN2 70 5e-12
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 70 5e-12
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 70 5e-12
At3g59410 [J] KOG1035 eIF-2alpha kinase GCN2 70 5e-12
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 70 5e-12
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 69 7e-12
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 69 7e-12
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 69 7e-12
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 69 9e-12
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 69 9e-12
At1g09600 [D] KOG0600 Cdc2-related protein kinase 69 9e-12
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 69 1e-11
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 69 1e-11
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 69 1e-11
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 69 1e-11
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 69 1e-11
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 69 1e-11
CE28674 [T] KOG0201 Serine/threonine protein kinase 69 1e-11
CE21025 [D] KOG0580 Serine/threonine protein kinase 69 1e-11
CE07510 [T] KOG0201 Serine/threonine protein kinase 69 1e-11
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 69 1e-11
At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 69 1e-11
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 69 1e-11
YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8 68 2e-11
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 68 2e-11
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 68 2e-11
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 68 2e-11
At1g57700 [D] KOG0600 Cdc2-related protein kinase 68 2e-11
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 68 2e-11
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 68 2e-11
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 68 2e-11
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 68 2e-11
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 68 2e-11
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 68 2e-11
YPR161c [D] KOG0600 Cdc2-related protein kinase 67 3e-11
YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 67 3e-11
YOL128c [G] KOG0658 Glycogen synthase kinase-3 67 3e-11
YGR040w [T] KOG0660 Mitogen-activated protein kinase 67 3e-11
CE24971 [T] KOG0660 Mitogen-activated protein kinase 67 3e-11
CE01583 [T] KOG0660 Mitogen-activated protein kinase 67 3e-11
At4g10010 [D] KOG0600 Cdc2-related protein kinase 67 3e-11
7296166 [T] KOG0614 cGMP-dependent protein kinase 67 3e-11
YOR233w [T] KOG0583 Serine/threonine protein kinase 67 3e-11
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 67 3e-11
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 67 3e-11
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 67 3e-11
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 67 3e-11
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 67 3e-11
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 67 3e-11
ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit 67 3e-11
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 67 3e-11
At1g71530 [D] KOG0600 Cdc2-related protein kinase 67 3e-11
YPL209c [D] KOG0580 Serine/threonine protein kinase 67 5e-11
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 67 5e-11
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 67 5e-11
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 67 5e-11
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 67 5e-11
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 67 5e-11
CE08727 [G] KOG0658 Glycogen synthase kinase-3 67 5e-11
At1g33770 [D] KOG0600 Cdc2-related protein kinase 67 5e-11
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 67 5e-11
YPL141c [T] KOG0583 Serine/threonine protein kinase 66 6e-11
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 66 6e-11
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 66 6e-11
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 66 6e-11
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 66 6e-11
At5g39440 [T] KOG0583 Serine/threonine protein kinase 66 6e-11
At1g54610 [D] KOG0600 Cdc2-related protein kinase 66 6e-11
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 66 6e-11
7290150 [T] KOG0583 Serine/threonine protein kinase 66 6e-11
SPAC1D4.13 [T] KOG0581 Mitogen-activated protein kinase kinase (... 66 8e-11
Hs14589902 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 66 8e-11
Hs14589900 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 66 8e-11
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 66 8e-11
CE06762 [T] KOG0660 Mitogen-activated protein kinase 66 8e-11
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 66 8e-11
At4g22940 [D] KOG0600 Cdc2-related protein kinase 66 8e-11
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 66 8e-11
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 66 8e-11
YKL161c [T] KOG0660 Mitogen-activated protein kinase 65 1e-10
YDR507c [D] KOG0588 Serine/threonine protein kinase 65 1e-10
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 65 1e-10
CE28643 [T] KOG0583 Serine/threonine protein kinase 65 1e-10
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 65 1e-10
CE07458 [T] KOG0583 Serine/threonine protein kinase 65 1e-10
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 65 1e-10
At3g01090 [T] KOG0583 Serine/threonine protein kinase 65 1e-10
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 65 1e-10
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 65 1e-10
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 65 1e-10
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 65 1e-10
CE27768 [R] KOG0586 Serine/threonine protein kinase 65 1e-10
CE23838 [R] KOG0586 Serine/threonine protein kinase 65 1e-10
At3g29160 [T] KOG0583 Serine/threonine protein kinase 65 1e-10
7302048 [J] KOG1035 eIF-2alpha kinase GCN2 65 1e-10
7291043 [T] KOG0660 Mitogen-activated protein kinase 65 1e-10
7290147 [T] KOG0583 Serine/threonine protein kinase 65 1e-10
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 65 2e-10
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 65 2e-10
Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 65 2e-10
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 65 2e-10
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 65 2e-10
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 65 2e-10
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE27220 [T] KOG0660 Mitogen-activated protein kinase 65 2e-10
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 65 2e-10
CE04172 [R] KOG0667 Dual-specificity tyrosine-phosphorylation re... 65 2e-10
CE02604 [T] KOG0695 Serine/threonine protein kinase 65 2e-10
At5g50860 [D] KOG0600 Cdc2-related protein kinase 65 2e-10
At5g39420 [D] KOG0600 Cdc2-related protein kinase 65 2e-10
At3g15220 [T] KOG0201 Serine/threonine protein kinase 65 2e-10
At1g53050 [D] KOG0600 Cdc2-related protein kinase 65 2e-10
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 64 2e-10
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 64 2e-10
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 64 2e-10
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 64 2e-10
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 64 2e-10
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 64 2e-10
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 64 2e-10
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 64 2e-10
CE29318 [T] KOG0660 Mitogen-activated protein kinase 64 2e-10
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 64 2e-10
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 64 2e-10
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 64 2e-10
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 64 2e-10
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 64 2e-10
SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (... 64 3e-10
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 64 3e-10
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 64 3e-10
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 64 3e-10
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 64 3e-10
Hs22065589 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 64 3e-10
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 64 3e-10
Hs11125768 [J] KOG1035 eIF-2alpha kinase GCN2 64 3e-10
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 64 3e-10
At5g57630 [T] KOG0583 Serine/threonine protein kinase 64 3e-10
At5g56580 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 64 3e-10
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 64 3e-10
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 64 4e-10
YDR523c [T] KOG0201 Serine/threonine protein kinase 64 4e-10
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 64 4e-10
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 64 4e-10
At1g03740 [D] KOG0600 Cdc2-related protein kinase 64 4e-10
7300224 [T] KOG0201 Serine/threonine protein kinase 64 4e-10
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 63 5e-10
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 63 5e-10
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 5e-10
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 63 5e-10
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 63 5e-10
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 63 5e-10
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 63 5e-10
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 63 5e-10
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 63 5e-10
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 63 5e-10
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 63 7e-10
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 63 7e-10
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 63 7e-10
HsM4506099 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 63 7e-10
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 63 7e-10
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 63 7e-10
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 63 7e-10
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 63 7e-10
Hs21618351 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 63 7e-10
Hs21618349 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 63 7e-10
Hs21618347 [T] KOG0984 Mitogen-activated protein kinase (MAPK) k... 63 7e-10
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 63 7e-10
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 63 7e-10
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 63 7e-10
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 63 7e-10
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 63 7e-10
At1g53165 [T] KOG0201 Serine/threonine protein kinase 63 7e-10
7296346 [R] KOG0663 Protein kinase PITSLRE and related kinases 63 7e-10
YLR096w [T] KOG0583 Serine/threonine protein kinase 62 9e-10
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 62 9e-10
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 62 9e-10
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 62 9e-10
CE23605 [T] KOG0665 Jun-N-terminal kinase (JNK) 62 9e-10
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 62 9e-10
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 62 9e-10
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 62 9e-10
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 62 9e-10
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 62 9e-10
7300559 [T] KOG4279 Serine/threonine protein kinase 62 9e-10
YHR030c [T] KOG0660 Mitogen-activated protein kinase 62 1e-09
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 62 1e-09
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 62 1e-09
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 62 1e-09
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 62 1e-09
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 62 1e-09
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 62 1e-09
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 62 1e-09
Hs21735544 [T] KOG0983 Mitogen-activated protein kinase (MAPK) k... 62 1e-09
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 62 1e-09
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 62 1e-09
CE16081 [T] KOG0583 Serine/threonine protein kinase 62 1e-09
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 62 1e-09
At4g19110 [T] KOG0661 MAPK related serine/threonine protein kinase 62 1e-09
At1g18670 [D] KOG0600 Cdc2-related protein kinase 62 1e-09
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 62 1e-09
7299793 [T] KOG0583 Serine/threonine protein kinase 62 1e-09
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 62 1e-09
YBL016w [T] KOG0660 Mitogen-activated protein kinase 62 1e-09
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 62 1e-09
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 62 1e-09
At4g32830 [D] KOG0580 Serine/threonine protein kinase 62 1e-09
At4g13020 [T] KOG0661 MAPK related serine/threonine protein kinase 62 1e-09
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 62 1e-09
At2g40120 [R] KOG0667 Dual-specificity tyrosine-phosphorylation ... 62 1e-09
7301213 [R] KOG0589 Serine/threonine protein kinase 62 1e-09
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 62 1e-09
YDR477w [T] KOG0583 Serine/threonine protein kinase 61 2e-09
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 61 2e-09
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 61 2e-09
Hs20553830 [J] KOG1035 eIF-2alpha kinase GCN2 61 2e-09
At2g45490 [D] KOG0580 Serine/threonine protein kinase 61 2e-09
At2g38490 [T] KOG0583 Serine/threonine protein kinase 61 2e-09
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 61 2e-09
YDR122w [T] KOG0583 Serine/threonine protein kinase 61 2e-09
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 61 2e-09
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 2e-09
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 61 2e-09
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 61 2e-09
CE28650 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 61 2e-09
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 61 2e-09
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 61 2e-09
At3g05050 [D] KOG0600 Cdc2-related protein kinase 61 2e-09
At2g32510 [T] KOG0198 MEKK and related serine/threonine protein ... 61 2e-09
At2g25880 [D] KOG0580 Serine/threonine protein kinase 61 2e-09
At1g74330 [D] KOG0600 Cdc2-related protein kinase 61 2e-09
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 61 2e-09
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 61 2e-09
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 60 3e-09
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 60 3e-09
Hs21735542 [T] KOG0983 Mitogen-activated protein kinase (MAPK) k... 60 3e-09
Hs20502986 [T] KOG0660 Mitogen-activated protein kinase 60 3e-09
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 60 3e-09
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 60 3e-09
CE24761 [D] KOG0580 Serine/threonine protein kinase 60 3e-09
At5g50180 [T] KOG0192 Tyrosine kinase specific for activated (GT... 60 3e-09
At5g19010 [T] KOG0660 Mitogen-activated protein kinase 60 3e-09
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 60 3e-09
At4g24400 [T] KOG0583 Serine/threonine protein kinase 60 3e-09
At1g73670 [T] KOG0660 Mitogen-activated protein kinase 60 3e-09
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 60 3e-09
7292830 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kina... 60 3e-09
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 60 4e-09
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 60 4e-09
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 60 4e-09
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 60 4e-09
At5g44290 [D] KOG0600 Cdc2-related protein kinase 60 4e-09
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 60 4e-09
7303111 [T] KOG0695 Serine/threonine protein kinase 60 4e-09
7297776 [D] KOG0580 Serine/threonine protein kinase 60 4e-09
7297080 [T] KOG0583 Serine/threonine protein kinase 60 4e-09
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 60 4e-09
YOR061w [TDK] KOG0668 Casein kinase II alpha subunit 60 6e-09
YKL116c [R] KOG0586 Serine/threonine protein kinase 60 6e-09
YHR102w [T] KOG0201 Serine/threonine protein kinase 60 6e-09
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 60 6e-09
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 60 6e-09
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 60 6e-09
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 60 6e-09
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 60 6e-09
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 60 6e-09
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 60 6e-09
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 60 6e-09
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 60 6e-09
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 60 6e-09
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 60 6e-09
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 60 6e-09
At2g26980 [T] KOG0583 Serine/threonine protein kinase 60 6e-09
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 60 6e-09
At1g18150 [T] KOG0660 Mitogen-activated protein kinase 60 6e-09
7299438 [R] KOG0586 Serine/threonine protein kinase 60 6e-09
7296128 [T] KOG0583 Serine/threonine protein kinase 60 6e-09
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 59 7e-09
YKL101w [D] KOG0588 Serine/threonine protein kinase 59 7e-09
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 59 7e-09
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 59 7e-09
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 59 7e-09
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 59 7e-09
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 59 7e-09
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 59 7e-09
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 59 7e-09
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 59 7e-09
Hs4506539 [T] KOG0192 Tyrosine kinase specific for activated (GT... 59 7e-09
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 59 7e-09
Hs21729899 [T] KOG0581 Mitogen-activated protein kinase kinase (... 59 7e-09
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 59 7e-09
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 59 7e-09
CE28479 [T] KOG0583 Serine/threonine protein kinase 59 7e-09
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 59 7e-09
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 59 7e-09
At3g20860 [R] KOG0589 Serine/threonine protein kinase 59 7e-09
At1g66460 [T] KOG1187 Serine/threonine protein kinase 59 7e-09
At1g54510 [R] KOG0589 Serine/threonine protein kinase 59 7e-09
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 59 7e-09
7296749 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 59 7e-09
7290249 [R] KOG0586 Serine/threonine protein kinase 59 7e-09
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 59 9e-09
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 9e-09
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 59 9e-09
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 59 9e-09
CE29020 [T] KOG0660 Mitogen-activated protein kinase 59 9e-09
At5g01810 [T] KOG0583 Serine/threonine protein kinase 59 9e-09
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 59 9e-09
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 59 9e-09
At1g29230 [T] KOG0583 Serine/threonine protein kinase 59 9e-09
At1g23700 [T] KOG0582 Ste20-like serine/threonine protein kinase 59 9e-09
7295638 [T] KOG0603 Ribosomal protein S6 kinase 59 9e-09
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 59 9e-09
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 59 1e-08
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 59 1e-08
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 59 1e-08
SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase 59 1e-08
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 59 1e-08
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 59 1e-08
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 59 1e-08
Hs4506101 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 59 1e-08
Hs21729897 [T] KOG0581 Mitogen-activated protein kinase kinase (... 59 1e-08
Hs21729895 [T] KOG0581 Mitogen-activated protein kinase kinase (... 59 1e-08
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 59 1e-08
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 59 1e-08
CE18366 [T] KOG0583 Serine/threonine protein kinase 59 1e-08
CE17284 [T] KOG0583 Serine/threonine protein kinase 59 1e-08
At3g14720 [T] KOG0660 Mitogen-activated protein kinase 59 1e-08
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 59 1e-08
7303211 [T] KOG4717 Serine/threonine protein kinase 59 1e-08
7302464 [R] KOG0586 Serine/threonine protein kinase 59 1e-08
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 59 1e-08
YPR054w [T] KOG0660 Mitogen-activated protein kinase 58 2e-08
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 58 2e-08
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 58 2e-08
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 58 2e-08
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 58 2e-08
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 58 2e-08
>YFL029c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 368
Score = 162 bits (410), Expect = 6e-40
Identities = 111/333 (33%), Positives = 174/333 (51%), Gaps = 42/333 (12%)
Query: 28 VKRIDLELQRPPHNAHTELEILKTLSNK--HVIPLLGSE-TSPRYVTFKFKRYQCDLNQF 84
+K + L+ PPHNA E+ IL L NK H++PLL S+ T + F + +L +F
Sbjct: 30 IKCLALDFDIPPHNAKFEVSILNKLGNKCKHILPLLESKATDNNDLLLLFPFEEMNLYEF 89
Query: 85 MDQHWKA---KYNPY----------LLDNSTKTYSNTIPLD-HSTVIIRQIIEGLVYIHG 130
M H+K K NPY + D + Y+N + ++ +S RQ++EG+ ++H
Sbjct: 90 MQMHYKRDRRKKNPYYDLLNPSIPIVADPPVQKYTNQLDVNRYSLSFFRQMVEGIAFLHE 149
Query: 131 NGIIHRDVKPQNIMLNSYNEVV-----LGDFGISYNRNLDNE-------AKTCDCSTSIY 178
N IIHRD+KPQNIML + V + DFGISY+ +++ +K D ST IY
Sbjct: 150 NKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIY 209
Query: 179 KAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDEC----SDIKLV 234
KAPE+LF V Y +D+W+L ++ISQ + +T +ID D+ SD +L+
Sbjct: 210 KAPEVLFGVKCYDGGVDVWSLLIIISQWFQRETSRMGHVPAMIDDGSDDMNSDGSDFRLI 269
Query: 235 LTLFDKFGKPSNEDWPQVTKN---ESFNGMFGNVSSDNFLHRRPIDEQLIQVYKWMPLIT 291
++F+K G PS + W +V ++ ++F GMFG ++ + D Q+ V + MP +
Sbjct: 270 CSIFEKLGIPSIQKWEEVAQHGSVDAFVGMFGADGDGKYVLDQEKDVQISIVERNMPRLD 329
Query: 292 D------NPKLAKMWLRMVKFDGNLRISAEQLL 318
+ K L MV F N R S +++L
Sbjct: 330 EIADVKVKQKFINCILGMVSFSPNERWSCQRIL 362
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 104 bits (260), Expect = 1e-22
Identities = 70/289 (24%), Positives = 135/289 (46%), Gaps = 43/289 (14%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHW 89
R+DLE++ P A E+ +LK L + +++ LL + R + F+ DL ++MD
Sbjct: 36 RLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDS-- 93
Query: 90 KAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYN 149
T + +PL + Q+++G+ + H + +IHRD+KPQN+++N
Sbjct: 94 --------------TPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELG 139
Query: 150 EVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWND 209
+ L DFG++ + T + T Y+APE+L Y +DIW++ + +++
Sbjct: 140 AIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTR 199
Query: 210 KTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDN 269
K F S+I + +F G PS + WP VT+ + G F +
Sbjct: 200 KAL------------FPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWT--- 244
Query: 270 FLHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
R+ ++E + + P+ + ++++++D + RI+A+ L
Sbjct: 245 ---RKGLEEIVPNL---------EPEGRDLLMQLLQYDPSQRITAKTAL 281
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 102 bits (253), Expect = 1e-21
Identities = 78/296 (26%), Positives = 133/296 (44%), Gaps = 48/296 (16%)
Query: 25 DIVVKRIDLE--LQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLN 82
D+ +K+I LE + P A E+ +LK L + +V+ L S + F+ DL
Sbjct: 33 DVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLK 92
Query: 83 QFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQN 142
+ MD+ K + P L+ K+Y + QI++ + + H N I+HRD+KPQN
Sbjct: 93 KLMDKK-KDVFTPQLI----KSY------------MHQILDAVGFCHTNRILHRDLKPQN 135
Query: 143 IMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVL 202
+++++ ++ L DFG++ N+ A T + T Y+APE+L Y +DIW+L +
Sbjct: 136 LLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCI 195
Query: 203 ISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMF 262
S++ ++ F S+I + +F P +WP VT+ F F
Sbjct: 196 FSEMIMRRSL------------FPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKF 243
Query: 263 GNVSSDNFLHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
N MP + ++ + M+ +D NLRISA+ L
Sbjct: 244 PRWEGTN-----------------MPQPITEHEAHELIMSMLCYDPNLRISAKDAL 282
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 100 bits (250), Expect = 2e-21
Identities = 74/298 (24%), Positives = 139/298 (45%), Gaps = 43/298 (14%)
Query: 26 IVVKRIDLELQR-PPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQF 84
+ +K + L+ + P A E+ ++K L +++++ L + +T F+ DL ++
Sbjct: 33 VALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKY 92
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNT---IPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQ 141
MD ++T NT + L+ Q+++GL + H N I+HRD+KPQ
Sbjct: 93 MD---------------SRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQ 137
Query: 142 NIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAV 201
N+++N ++ LGDFG++ + + + T Y+AP++L Y IDIW+
Sbjct: 138 NLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGC 197
Query: 202 LISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGM 261
+++++ K F +D + + +FD G P+ WP VTK +N
Sbjct: 198 ILAEMITGKPL------------FPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYN-- 243
Query: 262 FGNVSSDNFLHRRPID-EQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
N R P D Q++Q + PL + L +++ + ++R+SA+Q L
Sbjct: 244 ------PNIQQRPPRDLRQVLQPHTKEPL---DGNLMDFLHGLLQLNPDMRLSAKQAL 292
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 99.8 bits (247), Expect = 5e-21
Identities = 71/298 (23%), Positives = 132/298 (43%), Gaps = 52/298 (17%)
Query: 26 IVVKRIDLELQR-PPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQF 84
+ +K I LE + P A E+ +LK L + +++ L + + +T F+ DL Q+
Sbjct: 218 VALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY 277
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIM 144
MD N + + + + + QI+ GL Y H ++HRD+KPQN++
Sbjct: 278 MDD-----------------CGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLL 320
Query: 145 LNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLIS 204
+N E+ L DFG++ +++ + + + T Y+ P++L S Y +ID+W + +
Sbjct: 321 INEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYLTQIDMWGVGCIFF 380
Query: 205 QLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGN 264
++ + + ++ L+ L G PS E WP ++ NE F
Sbjct: 381 EMASGRPLFPGSTVE---------DELHLIFRL---LGTPSQETWPGISSNEEFKNY--- 425
Query: 265 VSSDNFLHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVK----FDGNLRISAEQLL 318
NF YK PLI P+L + +++ ++ R+SAE+ +
Sbjct: 426 ----NF-----------PKYKPEPLINHAPRLDSEGIELIRKFLQYESKKRVSAEEAM 468
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 99.0 bits (245), Expect = 8e-21
Identities = 73/289 (25%), Positives = 124/289 (42%), Gaps = 43/289 (14%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHW 89
R+D E + P A E+ +LK L++ +++ LL + + F+ DL +FMD
Sbjct: 36 RLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDA-- 93
Query: 90 KAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYN 149
+ IPL + Q+++GL + H + ++HRD+KPQN+++N+
Sbjct: 94 --------------SALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEG 139
Query: 150 EVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWND 209
+ L DFG++ + T + T Y+APE+L Y +DIW+L + +++
Sbjct: 140 AIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTR 199
Query: 210 KTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDN 269
+ F S+I + +F G P WP VT + F + +
Sbjct: 200 RAL------------FPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQD 247
Query: 270 FLHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
F P PL D L +M+ +D N RISA+ L
Sbjct: 248 FSKVVP------------PLDEDGRSLLS---QMLHYDPNKRISAKAAL 281
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 96.3 bits (238), Expect = 5e-20
Identities = 73/280 (26%), Positives = 134/280 (47%), Gaps = 45/280 (16%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPLLG--SETSPRYVTFKFKRYQCDL 81
+ +K+I LE + P A E+ +LK L + +++ L + S Y+ F+F DL
Sbjct: 30 VAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEF--LSMDL 87
Query: 82 NQFMDQHWKAKYNPYLLDNS-TKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKP 140
+++D +Y +D+S K+Y + QI++G+V+ H ++HRD+KP
Sbjct: 88 KKYLDSIPPGQY----MDSSLVKSY------------LYQILQGIVFCHSRRVLHRDLKP 131
Query: 141 QNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALA 200
QN++++ + L DFG++ + T + T Y++PE+L + Y +DIW++
Sbjct: 132 QNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIG 191
Query: 201 VLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNG 260
+ ++L K F S+I + +F G P+NE WP+V + +
Sbjct: 192 TIFAELATKKPL------------FHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 239
Query: 261 MF-----GNVSSDNFLHRRPIDEQLIQVYKWMPLITDNPK 295
F G+++S H + +DE + + M LI D K
Sbjct: 240 TFPKWKPGSLAS----HVKNLDENGLDLLSKM-LIYDPAK 274
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 94.7 bits (234), Expect = 2e-19
Identities = 68/298 (22%), Positives = 135/298 (44%), Gaps = 52/298 (17%)
Query: 26 IVVKRIDLELQR-PPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQF 84
+ +K I LE + P A E+ +LK L + +++ L + + +T F+ DL Q+
Sbjct: 191 VALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY 250
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIM 144
+D N I + + + + Q++ GL Y H ++HRD+KPQN++
Sbjct: 251 LDD-----------------CGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLL 293
Query: 145 LNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLIS 204
+N E+ L DFG++ +++ + + + T Y+ P++L ++Y +ID+W + +
Sbjct: 294 INERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFY 353
Query: 205 QLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGN 264
++ + F + + + +F G P+ E WP + NE F
Sbjct: 354 EMATGRPL------------FPGSTVEEQLHFIFRILGTPTEETWPGILSNEEF------ 395
Query: 265 VSSDNFLHRRPIDEQLIQVYKWMPLITDNPKL----AKMWLRMVKFDGNLRISAEQLL 318
+ N+ Y+ L++ P+L A + ++++F+G RISAE +
Sbjct: 396 -KTYNY-----------PKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAM 441
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 94.7 bits (234), Expect = 2e-19
Identities = 68/298 (22%), Positives = 135/298 (44%), Gaps = 52/298 (17%)
Query: 26 IVVKRIDLELQR-PPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQF 84
+ +K I LE + P A E+ +LK L + +++ L + + +T F+ DL Q+
Sbjct: 143 VALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQY 202
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIM 144
+D N I + + + + Q++ GL Y H ++HRD+KPQN++
Sbjct: 203 LDD-----------------CGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLL 245
Query: 145 LNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLIS 204
+N E+ L DFG++ +++ + + + T Y+ P++L ++Y +ID+W + +
Sbjct: 246 INERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFY 305
Query: 205 QLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGN 264
++ + F + + + +F G P+ E WP + NE F
Sbjct: 306 EMATGRPL------------FPGSTVEEQLHFIFRILGTPTEETWPGILSNEEF------ 347
Query: 265 VSSDNFLHRRPIDEQLIQVYKWMPLITDNPKL----AKMWLRMVKFDGNLRISAEQLL 318
+ N+ Y+ L++ P+L A + ++++F+G RISAE +
Sbjct: 348 -KTYNY-----------PKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAM 393
>Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 90.9 bits (224), Expect = 2e-18
Identities = 66/282 (23%), Positives = 130/282 (45%), Gaps = 42/282 (14%)
Query: 39 PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLL 98
P A E +LK L + +++ L + +TF F+ DL Q+M QH +P+
Sbjct: 92 PFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQH-PGGLHPH-- 148
Query: 99 DNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGI 158
+ + + Q++ GL YIH ++HRD+KPQN++++ E+ L DFG+
Sbjct: 149 --------------NVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGL 194
Query: 159 SYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXX 218
+ +++ ++ + + T Y+ P+ L + Y E+DIW + +++ +
Sbjct: 195 ARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPL------ 248
Query: 219 XVIDIDFDECSDI-KLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLHRRPID 277
F S+I + + +++ G P+ + WP V+K ++N + + + LH
Sbjct: 249 ------FPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLH----- 297
Query: 278 EQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLLV 319
V+ + + + LA L+ D R+SA++ LV
Sbjct: 298 ----VVWNRLGRVPEAEDLASQMLKGFPRD---RVSAQEALV 332
>YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 88.6 bits (218), Expect = 1e-17
Identities = 61/242 (25%), Positives = 103/242 (42%), Gaps = 44/242 (18%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPL---LGSETSPRYVTFKFKRYQCDLNQFMD 86
R++ E + P A E+ +LK L + +++ L + S+ Y+ F+F
Sbjct: 43 RLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEF------------ 90
Query: 87 QHWKAKYNPYLLDNSTKTYSNTIPLDHST------VIIRQIIEGLVYIHGNGIIHRDVKP 140
LD K Y IP D + Q+ +G+ Y H + I+HRD+KP
Sbjct: 91 -----------LDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKP 139
Query: 141 QNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALA 200
QN+++N + LGDFG++ + A T + T Y+APE+L Y +D W++
Sbjct: 140 QNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIG 199
Query: 201 VLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNG 260
+ +++ N K F S+I + +F G P+ WP + F
Sbjct: 200 CIFAEMCNRKP------------IFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKP 247
Query: 261 MF 262
F
Sbjct: 248 SF 249
>7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 294
Score = 87.8 bits (216), Expect = 2e-17
Identities = 53/224 (23%), Positives = 107/224 (47%), Gaps = 28/224 (12%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHW 89
R+D + + P +A E+ +LK L +K+++ L+ S + +T F+ DL ++ D
Sbjct: 36 RLDEDDEGVPSSALREICLLKELKHKNIVRLIDVLHSDKKLTLVFEHCDQDLKKYFD--- 92
Query: 90 KAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYN 149
+ + I + + Q++ GL + H + ++HRD+KPQN+++N
Sbjct: 93 --------------SLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNG 138
Query: 150 EVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWND 209
E+ L DFG++ + + + + T Y+ P++LF Y ID+W+ ++++L D
Sbjct: 139 ELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAEL-AD 197
Query: 210 KTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVT 253
+ V+D ++ +F G P+ + WP V+
Sbjct: 198 AGRPLFPGSDVLD----------QLMKIFRVLGTPNEDSWPGVS 231
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 87.0 bits (214), Expect = 3e-17
Identities = 59/235 (25%), Positives = 106/235 (45%), Gaps = 32/235 (13%)
Query: 26 IVVKRIDLELQR-PPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQF 84
+ +K I LE + P A E+ +LK L + +++ L + R +T F+ DL Q+
Sbjct: 168 VALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQY 227
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIM 144
+D N + + + + + Q++ GL Y H I+HRD+KPQN++
Sbjct: 228 LDH-----------------CGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLL 270
Query: 145 LNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLIS 204
+N E+ L DFG++ +++ + + + T Y+ P++L + Y ID+W + +
Sbjct: 271 INERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHY 330
Query: 205 QLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTL-FDKFGKPSNEDWPQVTKNESF 258
++ + S +K L L F G P+ E WP VT F
Sbjct: 331 EMATGRPLFPG-------------STVKEELHLIFRLLGTPTEETWPGVTAFSEF 372
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 87.0 bits (214), Expect = 3e-17
Identities = 68/290 (23%), Positives = 131/290 (44%), Gaps = 35/290 (12%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHW 89
R++ E + P A E+ +LK L + +V+ L + F+ DL ++MDQ
Sbjct: 54 RLESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLFLIFEFLSFDLKRYMDQLG 113
Query: 90 KAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYN 149
K +Y P + K+Y+ QI++ + + H +IHRD+KPQN+++++
Sbjct: 114 KDEYLPL---ETLKSYTF------------QILQAMCFCHQRRVIHRDLKPQNLLVDNNG 158
Query: 150 EVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWND 209
+ L DFG++ + T + T Y+APE+L Y +D+W++ + +++
Sbjct: 159 AIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATK 218
Query: 210 KTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDN 269
K F S+I + +F G P+ +W V + F +N
Sbjct: 219 KPL------------FQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPK-WREN 265
Query: 270 FLHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLLV 319
FL + D+ K + D+ + + ++ +D +LR++A++ LV
Sbjct: 266 FLRDKFYDK------KTGKHLLDDTAFSLLEGLLI-YDPSLRLNAKKALV 308
>7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 509
Score = 86.7 bits (213), Expect = 4e-17
Identities = 56/231 (24%), Positives = 103/231 (44%), Gaps = 33/231 (14%)
Query: 26 IVVKRIDL-ELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQF 84
+ +K I L E + P A E +LK L + +++ L + +TF F+ DL+Q+
Sbjct: 218 VALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQY 277
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQN 142
M++H LDH V + Q++ GL Y H ++HRDVKPQN
Sbjct: 278 MEKHPGG-------------------LDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQN 318
Query: 143 IMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVL 202
++++ E+ L DFG++ +++ + + + T Y+ P++L + Y +D+W + +
Sbjct: 319 LLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCI 378
Query: 203 ISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVT 253
++ +D +F G P+ + WP VT
Sbjct: 379 FVEMVTGMPTFPGIRDTYDQLD-----------KIFKLLGTPTEDTWPGVT 418
>CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 85.9 bits (211), Expect = 7e-17
Identities = 56/225 (24%), Positives = 108/225 (47%), Gaps = 28/225 (12%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHW 89
R+D + + P +A E+ IL+ L +++V+ L S +T F+ DL +F D
Sbjct: 36 RLDDDDEGVPSSALREICILRELKHRNVVRLYDVVHSENKLTLVFEYCDQDLKKFFDS-- 93
Query: 90 KAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYN 149
N Y+ + ++ ++ Q++ GL + H + ++HRD+KPQN+++N+
Sbjct: 94 ---LNGYMDAQTARS------------LMLQLLRGLSFCHAHHVLHRDLKPQNLLINTNG 138
Query: 150 EVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWND 209
+ L DFG++ + + + T Y+ P++LF Y ID+W+ + +++ N
Sbjct: 139 TLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEISNA 198
Query: 210 KTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTK 254
D+D D+ I F + G PS ++WP +T+
Sbjct: 199 GRPLFPGA----DVD-DQLKRI------FKQLGSPSEDNWPSITQ 232
>CE11556 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 305
Score = 85.9 bits (211), Expect = 7e-17
Identities = 44/133 (33%), Positives = 73/133 (54%), Gaps = 14/133 (10%)
Query: 120 QIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS--YNRNLDNEAKTCDCSTSI 177
QI+ G+ Y+H I+HRD+KP+NI++ S N V + DFG + Y N+ + +T
Sbjct: 92 QILSGIAYLHSKEIMHRDIKPENILVTSRNVVKIADFGQACFYMPKDPNQEYDVNVATRW 151
Query: 178 YKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTL 237
Y+APELLF YK ++DIWA+ ++++L K F S+++ + +
Sbjct: 152 YRAPELLFGSKKYKPDVDIWAIGCILAELVRGKP------------IFPGRSELEQISII 199
Query: 238 FDKFGKPSNEDWP 250
F G P+ ++WP
Sbjct: 200 FGVLGTPNEDNWP 212
>At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 398
Score = 85.9 bits (211), Expect = 7e-17
Identities = 58/229 (25%), Positives = 100/229 (43%), Gaps = 31/229 (13%)
Query: 26 IVVKRIDLELQRPPHN--AHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ +K+I L ++ N A E+++LK L + H+I L+ + + F+ + DL
Sbjct: 37 VAIKKIRLGKEKEGVNVTALREIKLLKELKHPHIIELIDAFPHKENLHIVFEFMETDLEA 96
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
+ N YL K+Y ++ I++GL Y HG ++HRD+KP N+
Sbjct: 97 VIRDR-----NLYLSPGDVKSY------------LQMILKGLEYCHGKWVLHRDMKPNNL 139
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
++ ++ L DFG++ T Y+APELLF Y +D+WA +
Sbjct: 140 LIGPNGQLKLADFGLARIFGSPGRKFTHQVFARWYRAPELLFGAKQYDGAVDVWAAGCIF 199
Query: 204 SQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQV 252
++L + SDI + +F FG P + WP +
Sbjct: 200 AELLLRRPFLQGN------------SDIDQLSKIFAAFGTPKADQWPDM 236
>At1g18040 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 391
Score = 85.9 bits (211), Expect = 7e-17
Identities = 61/231 (26%), Positives = 101/231 (43%), Gaps = 31/231 (13%)
Query: 26 IVVKRIDLELQRPPHN--AHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ +K+I L QR N A E+++LK L + H+I L+ + + F+ + DL
Sbjct: 38 VAIKKIRLGKQREGVNITALREIKMLKELKHPHIILLIDAFPHKENLHLVFEFMETDLEA 97
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
+ N +L K+Y + +GL Y H ++HRD+KP N+
Sbjct: 98 VIRDS-----NIFLSPADIKSY------------LLMTFKGLAYCHDKWVLHRDMKPNNL 140
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
++ ++ L DFG++ N T Y+APELLF Y +D+WA+A +
Sbjct: 141 LIGVDGQLKLADFGLARIFGSPNRKFTHQVFARWYRAPELLFGAKQYGAAVDVWAVACIF 200
Query: 204 SQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTK 254
++L + SDI + +F FG P + WP +TK
Sbjct: 201 AELLLRRPFLQGN------------SDIDQLSKIFAAFGTPKADQWPDLTK 239
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 85.1 bits (209), Expect = 1e-16
Identities = 56/228 (24%), Positives = 109/228 (47%), Gaps = 32/228 (14%)
Query: 28 VKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQ 87
V RID + + P A E+ ++K L + +++ L + + F+ + DL ++MD
Sbjct: 33 VIRIDAD-EGTPSTAIREISLMKELRHPNIMSLSDVLQTENKLMLVFEYMEKDLKKYMD- 90
Query: 88 HWKAKYNPYLLDNSTKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNIML 145
TY N L S V +Q+++G+ + H N ++HRD+KPQN+++
Sbjct: 91 ----------------TYGNQGALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLI 134
Query: 146 NSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQ 205
NS E+ L DFG++ + + + + T Y+AP++L Y IDIW++ ++++
Sbjct: 135 NSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAE 194
Query: 206 LWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVT 253
+ + F ++ +L +F G P+ + WP ++
Sbjct: 195 MATGRPL------------FAGSNNEDQLLKIFRLLGTPTEQSWPGIS 230
>Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 346
Score = 85.1 bits (209), Expect = 1e-16
Identities = 55/209 (26%), Positives = 99/209 (47%), Gaps = 31/209 (14%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKT 104
E+++L+ LS+ ++I LL + ++ F + DL + DNS
Sbjct: 62 EIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIK------------DNSL-- 107
Query: 105 YSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNL 164
+ H + ++GL Y+H + I+HRD+KP N++L+ + L DFG++ +
Sbjct: 108 ---VLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGS 164
Query: 165 DNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDID 224
N A T T Y+APELLF Y +D+WA+ ++++L ++ +
Sbjct: 165 PNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAEL-------------LLRVP 211
Query: 225 F-DECSDIKLVLTLFDKFGKPSNEDWPQV 252
F SD+ + +F+ G P+ E WP +
Sbjct: 212 FLPGDSDLDQLTRIFETLGTPTEEQWPDM 240
>Hs20986512 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 85.1 bits (209), Expect = 1e-16
Identities = 81/295 (27%), Positives = 132/295 (44%), Gaps = 43/295 (14%)
Query: 26 IVVKRIDLELQRPPHNAHT--ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ VK++ Q H T EL +LK + +++VI LL T R L +
Sbjct: 50 VAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAR-----------SLEE 98
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
F D + L+N K T DH +I QI+ GL YIH IIHRD+KP N+
Sbjct: 99 FNDVYLVTHLMGADLNNIVKCQKLTD--DHVQFLIYQILRGLKYIHSADIIHRDLKPSNL 156
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
+N E+ + DFG++ R+ D+E T +T Y+APE++ + +Y +DIW++ ++
Sbjct: 157 AVNEDCELKILDFGLA--RHTDDE-MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIM 213
Query: 204 SQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFG 263
++L +T D +KL+L L G P E +
Sbjct: 214 AELLTGRTLFPGT---------DHIDQLKLILRL---VGTPGAE-------------LLK 248
Query: 264 NVSSDNFLHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
+SS++ + Q+ ++ I NP + +M+ D + RI+A Q L
Sbjct: 249 KISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQAL 303
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 84.7 bits (208), Expect = 2e-16
Identities = 54/189 (28%), Positives = 97/189 (50%), Gaps = 22/189 (11%)
Query: 19 DLELFPDIVVKRIDL-ELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRY 77
D E + +KRI L E + P A E+ ILK LS++++I L+ + +T F
Sbjct: 23 DTETKEKVALKRIRLNEKEGMPGTALREISILKKLSHRNIISLVSIIHTDALLTMVFPFI 82
Query: 78 QCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRD 137
+L +++ + T N + L + Q+I G+ Y+H ++HRD
Sbjct: 83 DYELKKYIGMN---------------TGKNIMEL------VNQLICGVHYLHRMNVVHRD 121
Query: 138 VKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIW 197
+KPQNI++ S + + DFG+S + + + + T Y++PELL ++Y+F +DIW
Sbjct: 122 LKPQNILVTSDGVLKIADFGLSRSLEIRVPPYSSEVVTLWYRSPELLMGSTSYRFYVDIW 181
Query: 198 ALAVLISQL 206
+L +I ++
Sbjct: 182 SLGCIIYEM 190
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 84.3 bits (207), Expect = 2e-16
Identities = 45/182 (24%), Positives = 95/182 (51%), Gaps = 18/182 (9%)
Query: 26 IVVKRIDLELQR-PPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQF 84
+ +K I LE + P A E+ +L+ L + +V+ L + R +T F+ DL Q+
Sbjct: 387 VALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQY 446
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIM 144
MD + +N + +++ + + Q++ GL Y H ++HRD+KPQN++
Sbjct: 447 MD-----------------SCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLL 489
Query: 145 LNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLIS 204
+ + E+ L DFG++ +++ + + + T Y+ P++L ++Y ID+W + ++
Sbjct: 490 ITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILF 549
Query: 205 QL 206
++
Sbjct: 550 EM 551
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 84.3 bits (207), Expect = 2e-16
Identities = 45/182 (24%), Positives = 95/182 (51%), Gaps = 18/182 (9%)
Query: 26 IVVKRIDLELQR-PPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQF 84
+ +K I LE + P A E+ +L+ L + +V+ L + R +T F+ DL Q+
Sbjct: 264 VALKEIRLEQEEGAPCTAIREVSLLRNLRHANVVTLHDIIHTDRLLTLVFEYVDRDLKQY 323
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIM 144
MD + +N + +++ + + Q++ GL Y H ++HRD+KPQN++
Sbjct: 324 MD-----------------SCNNAMQMNNIRLFLYQLLRGLAYCHQRRVLHRDLKPQNLL 366
Query: 145 LNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLIS 204
+ + E+ L DFG++ +++ + + + T Y+ P++L ++Y ID+W + ++
Sbjct: 367 ITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYSTHIDMWGVGCILF 426
Query: 205 QL 206
++
Sbjct: 427 EM 428
>7298087 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 84.3 bits (207), Expect = 2e-16
Identities = 75/297 (25%), Positives = 134/297 (44%), Gaps = 44/297 (14%)
Query: 26 IVVKRIDLELQRPPHNAHT--ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ +K++ Q H T EL +LK + +++VI LL F + L+Q
Sbjct: 50 VAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLD--------VFHPGQPADSLDQ 101
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
F + L+N +T + DH ++ QI+ GL YIH G+IHRD+KP NI
Sbjct: 102 FQQVYMVTHLMDADLNNIIRTQK--LSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNI 159
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
+N E+ + DFG++ R ++E T +T Y+APE++ + +Y DIW++ ++
Sbjct: 160 AVNEDCELRILDFGLA--RPAESE-MTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIM 216
Query: 204 SQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFG 263
++L +T F I + + + G P++E F
Sbjct: 217 AELLTGRTL------------FPGTDHIHQLNLIMEVLGTPADE----------FMSRIS 254
Query: 264 NVSSDNFLHRRPI--DEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
+ S+ N++ P+ +++ NP + +M++ D + RI+AEQ L
Sbjct: 255 SESARNYIRSLPVMPRRNFRDIFRGA-----NPLAIDLLEKMLELDADKRITAEQAL 306
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 84.0 bits (206), Expect = 3e-16
Identities = 59/225 (26%), Positives = 105/225 (46%), Gaps = 28/225 (12%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHW 89
R+D + + P +A E+ +LK L +K+++ L S + +T F+ DL ++ D
Sbjct: 36 RLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDS-- 93
Query: 90 KAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYN 149
N L K++ + Q+++GL + H ++HRD+KPQN+++N
Sbjct: 94 ---CNGDLDPEIVKSF------------LFQLLKGLGFCHSRNVLHRDLKPQNLLINRNG 138
Query: 150 EVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWND 209
E+ L DFG++ + + + T Y+ P++LF Y ID+W+ + ++L N
Sbjct: 139 ELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANA 198
Query: 210 KTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTK 254
D+D D+ I F G P+ E WP +TK
Sbjct: 199 GRPLFPGN----DVD-DQLKRI------FRLLGTPTEEQWPSMTK 232
>At2g38620 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 311
Score = 84.0 bits (206), Expect = 3e-16
Identities = 63/241 (26%), Positives = 116/241 (47%), Gaps = 46/241 (19%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSN----------KHVIPLLGSETS--PR---YVTFKF 74
R++++ + P A E+ +L+ LS +HVI S S P+ Y+ F++
Sbjct: 36 RLEMDEEGIPPTALREISLLQMLSQSIYIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEY 95
Query: 75 KRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNG 132
DL +F+D H K SN PL+ S V + Q+ +G+ + H +G
Sbjct: 96 --LDTDLKKFIDSHRKG--------------SNPRPLEASLVQRFMFQLFKGVAHCHSHG 139
Query: 133 IIHRDVKPQNIMLNSYNEVV-LGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYK 191
++HRD+KPQN++L+ ++ + D G+S + +A T + T Y+APE+L ++Y
Sbjct: 140 VLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLKAYTHEIVTLWYRAPEVLLGSTHYS 199
Query: 192 FEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQ 251
+DIW++ + +++ + F S+ + +L +F G P+ + WP
Sbjct: 200 TAVDIWSVGCIFAEMIRRQAL------------FPGDSEFQQLLHIFRLLGTPTEQQWPG 247
Query: 252 V 252
V
Sbjct: 248 V 248
>Hs20986514 [T] KOG0660 Mitogen-activated protein kinase
Length = 297
Score = 83.6 bits (205), Expect = 4e-16
Identities = 69/236 (29%), Positives = 111/236 (46%), Gaps = 30/236 (12%)
Query: 26 IVVKRIDLELQRPPHNAHT--ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ VK++ Q H T EL +LK + +++VI LL T R L +
Sbjct: 50 VAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAR-----------SLEE 98
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
F D + L+N K T DH +I QI+ GL YIH IIHRD+KP N+
Sbjct: 99 FNDVYLVTHLMGADLNNIVKCQKLTD--DHVQFLIYQILRGLKYIHSADIIHRDLKPSNL 156
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
+N E+ + DFG++ R+ D+E T +T Y+APE++ + +Y +DIW++ ++
Sbjct: 157 AVNEDCELKILDFGLA--RHTDDE-MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIM 213
Query: 204 SQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
++L +T D +KL+L L G P E +++ + N
Sbjct: 214 AELLTGRTLFPGT---------DHIDQLKLILRL---VGTPGAELLKKISSESARN 257
>SPAC1D4.06c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 306
Score = 82.8 bits (203), Expect = 6e-16
Identities = 64/243 (26%), Positives = 111/243 (45%), Gaps = 41/243 (16%)
Query: 27 VVKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGS----ETSPRYVTFKFKRYQCDLN 82
V+K L +RPPH+A IL+++ + H+ ++ S E Y+ FK + L+
Sbjct: 38 VIKVQGLVFKRPPHDAMRGKLILESIGHPHIERIVDSFIDNEAGSVYLITSFKSFV--LS 95
Query: 83 QFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQN 142
MD+ I +D I+ QI L Y+ +GI+HRD+ P N
Sbjct: 96 DVMDE---------------------ISIDTKCKIVLQISSALEYLEKHGILHRDIHPNN 134
Query: 143 IMLNSYN-EVVLGDFGISYNRNLDNE---AKTCDCSTSIYKAPELLFSVSNYKFEIDIWA 198
I+L+S N L DF I++++ E T Y+A E LF +Y E+D W
Sbjct: 135 ILLDSMNGPAYLSDFSIAWSKQHPGEEVQELIPQIGTGHYRAIETLFGCHSYGHEVDRWT 194
Query: 199 LAVLISQLWNDKTQXXXXXXXVIDIDFDE--CSDIKLVLTLFDKFGKPSNEDWPQVTKNE 256
+LI++L++++ + D E S+++L ++ G P+ WP+++
Sbjct: 195 FGILIAELFSNQ--------ALFDDGSSEGWPSELRLTSSIIQTLGTPNPSMWPELSTFP 246
Query: 257 SFN 259
+N
Sbjct: 247 DWN 249
>Hs4503069 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 82.8 bits (203), Expect = 6e-16
Identities = 60/188 (31%), Positives = 96/188 (50%), Gaps = 18/188 (9%)
Query: 26 IVVKRIDLELQRPPHNAHT--ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ VK++ Q H T EL +LK + +++VI LL T R L +
Sbjct: 50 VAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAR-----------SLEE 98
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
F D + L+N K T DH +I QI+ GL YIH IIHRD+KP N+
Sbjct: 99 FNDVYLVTHLMGADLNNIVKCQKLTD--DHVQFLIYQILRGLKYIHSADIIHRDLKPSNL 156
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
+N E+ + DFG++ R+ D+E T +T Y+APE++ + +Y +DIW++ ++
Sbjct: 157 AVNEDCELKILDFGLA--RHTDDE-MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIM 213
Query: 204 SQLWNDKT 211
++L +T
Sbjct: 214 AELLTGRT 221
>Hs20986516 [T] KOG0660 Mitogen-activated protein kinase
Length = 307
Score = 82.8 bits (203), Expect = 6e-16
Identities = 60/188 (31%), Positives = 96/188 (50%), Gaps = 18/188 (9%)
Query: 26 IVVKRIDLELQRPPHNAHT--ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ VK++ Q H T EL +LK + +++VI LL T R L +
Sbjct: 50 VAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPAR-----------SLEE 98
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
F D + L+N K T DH +I QI+ GL YIH IIHRD+KP N+
Sbjct: 99 FNDVYLVTHLMGADLNNIVKCQKLTD--DHVQFLIYQILRGLKYIHSADIIHRDLKPSNL 156
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
+N E+ + DFG++ R+ D+E T +T Y+APE++ + +Y +DIW++ ++
Sbjct: 157 AVNEDCELKILDFGLA--RHTDDE-MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIM 213
Query: 204 SQLWNDKT 211
++L +T
Sbjct: 214 AELLTGRT 221
>At2g46070 [T] KOG0660 Mitogen-activated protein kinase
Length = 406
Score = 82.4 bits (202), Expect = 8e-16
Identities = 37/101 (36%), Positives = 63/101 (61%), Gaps = 1/101 (0%)
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD 165
+ T+ D ++ Q++ GL Y+H I+HRD++P N++LNS NE+ +GDFG++ + D
Sbjct: 170 NQTLTSDQCRFLVYQLLRGLKYVHSANILHRDLRPSNVLLNSKNELKIGDFGLARTTS-D 228
Query: 166 NEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ T T Y+APELL + S Y IDIW++ ++ ++
Sbjct: 229 TDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEI 269
>CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 527
Score = 82.0 bits (201), Expect = 1e-15
Identities = 43/136 (31%), Positives = 76/136 (55%), Gaps = 15/136 (11%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCD-CST 175
II Q+++GL ++H NG HRD+KP+NIM N V + DFG++ R + ++ D ST
Sbjct: 146 IIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLA--REIRSKPPYTDYVST 203
Query: 176 SIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVL 235
Y+APE+L ++Y ID+WAL ++++L+ ++ F S++ +
Sbjct: 204 RWYRAPEILLRSTSYNSPIDMWALGCIMAELY------------ILRPLFPGTSEMDQLF 251
Query: 236 TLFDKFGKPSNEDWPQ 251
+ G P+ ++WP+
Sbjct: 252 KIISILGTPNKDEWPE 267
>Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 451
Score = 81.6 bits (200), Expect = 1e-15
Identities = 56/219 (25%), Positives = 102/219 (46%), Gaps = 28/219 (12%)
Query: 34 ELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKY 93
E + P A E +LK L + +++ L + +T F+ DL Q+MD+H
Sbjct: 152 EEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKH----- 206
Query: 94 NPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVL 153
+ D+ + + Q++ GL YIH I+HRD+KPQN++++ E+ L
Sbjct: 207 ------------PGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKL 254
Query: 154 GDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQX 213
DFG++ +++ + + + T Y+ P++L + Y +D+W + + ++ Q
Sbjct: 255 ADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEM----IQG 310
Query: 214 XXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQV 252
+ DI D+ I LVL G P+ + WP V
Sbjct: 311 VAAFPGMKDIQ-DQLERIFLVL------GTPNEDTWPGV 342
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 80.9 bits (198), Expect = 2e-15
Identities = 59/243 (24%), Positives = 111/243 (45%), Gaps = 41/243 (16%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKH-------VIPLLGSETSPRYVTFKFKRYQCDLN 82
R++ E + P A E+ +LK +++++ ++ +L +E S Y+ F+F DL
Sbjct: 36 RLEDESEGVPSTAIREISLLKEVNDENNRSNCVRLLDILHAE-SKLYLVFEF--LDMDLK 92
Query: 83 QFMD---QHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
++MD + +P L+ T Q++ G+ + H IIHRD+K
Sbjct: 93 KYMDRISETGATSLDPRLVQKFTY----------------QLVNGVNFCHSRRIIHRDLK 136
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
PQN++++ + L DFG++ + + T + T Y+APE+L +Y +DIW++
Sbjct: 137 PQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIVTLWYRAPEVLLGSRHYSTGVDIWSV 196
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +++ F S+I + +F G P+ E WP VT + +
Sbjct: 197 GCIFAEMIRRSPL------------FPGDSEIDEIFKIFQVLGTPNEEVWPGVTLLQDYK 244
Query: 260 GMF 262
F
Sbjct: 245 STF 247
>CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 384
Score = 80.9 bits (198), Expect = 2e-15
Identities = 53/236 (22%), Positives = 110/236 (46%), Gaps = 16/236 (6%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFK---FKRYQCDLNQFMD 86
R D + + P E+ +K L + +++ L + ++ + F+++ + +M
Sbjct: 77 RTDRDEEGIPSTCLREISCIKDLQHDNIVTLFDIIYASHFLNYNNIFFEKFSSNSKLYMV 136
Query: 87 QHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLN 146
+ + LL+ T S +P ++ + Q++ L Y H I+HRD+KPQNI+++
Sbjct: 137 FEFIDRDLKNLLEMLEPTNS-VLPPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVS 195
Query: 147 SYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ + DFG++ N + + T + T Y+ PE+L Y +D+W+L + S++
Sbjct: 196 DSGVIKIADFGLARNFSFPSRNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEI 255
Query: 207 WNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMF 262
++K + EC +I + +F+ G P+ + WP V + +F
Sbjct: 256 ASNK-----------PLFPGEC-EISQLFKIFEIVGTPNIKSWPGVDSFPHYKAVF 299
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 80.9 bits (198), Expect = 2e-15
Identities = 58/240 (24%), Positives = 108/240 (44%), Gaps = 31/240 (12%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
I +K+I LE + P A E+ +LK + + +++ S + + F+ DL +
Sbjct: 30 IALKKIRLEQEDEGVPSTAIREISLLKEMQHSNIVKYDDVVHSEKRLYLVFEYLDLDLKK 89
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
MD ST +S + + + + QI+ G+ Y H + ++HRD+KPQN+
Sbjct: 90 HMD--------------STPDFSKDLHMIKT--YLYQILRGIAYCHSHRVLHRDLKPQNL 133
Query: 144 MLN-SYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVL 202
+++ N + L DFG++ + T + T Y+APE+L +Y +DIW++ +
Sbjct: 134 LIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSHHYSTPVDIWSVGCI 193
Query: 203 ISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMF 262
+++ + K F S+I + +F G P + W VT + F
Sbjct: 194 FAEMISQKPL------------FPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYKSAF 241
>At3g45640 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 80.9 bits (198), Expect = 2e-15
Identities = 60/207 (28%), Positives = 95/207 (44%), Gaps = 26/207 (12%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTC 171
+H + Q++ GL YIH IIHRD+KP N++LN+ ++ + DFG++ +N+ T
Sbjct: 139 EHCQYFLYQLLRGLKYIHSANIIHRDLKPSNLLLNANCDLKICDFGLA-RPTSENDFMTE 197
Query: 172 DCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDI 231
T Y+APELL + S+Y ID+W++ + +L N K F +
Sbjct: 198 YVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMNRKPL------------FPGKDHV 245
Query: 232 KLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLHRRPIDEQLIQVYKWMPLIT 291
+ L + G P+ D T NE + + R+P+ + V
Sbjct: 246 HQMRLLTELLGTPTESDL-GFTHNEDAKRYIRQLPN---FPRQPLAKLFSHV-------- 293
Query: 292 DNPKLAKMWLRMVKFDGNLRISAEQLL 318
NP + RM+ FD N RI+ EQ L
Sbjct: 294 -NPMAIDLVDRMLTFDPNRRITVEQAL 319
>SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase
Length = 593
Score = 80.5 bits (197), Expect = 3e-15
Identities = 59/230 (25%), Positives = 106/230 (45%), Gaps = 32/230 (13%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ +KRI LE ++ P E++IL+ L +K+++ LL V F+ DL
Sbjct: 303 VALKRIRLEQEKDGFPITTVREVKILQRLRHKNIVRLLEIMVEKSSVYMVFEYMDHDLTG 362
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
+ + + + P + + +K QI E L Y+H G++HRD+K NI
Sbjct: 363 VL-LNSQLHFTPGNIKHLSK----------------QIFEALAYLHHRGVLHRDIKGSNI 405
Query: 144 MLNSYNEVVLGDFGIS-YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVL 202
+LN+ ++ DFG++ +N + + T T ++ PELL + Y +DIW+ +
Sbjct: 406 LLNNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGETAYDTAVDIWSAGCI 465
Query: 203 ISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQV 252
+ +L+ K DE S ++++ +D G P WP+V
Sbjct: 466 VMELFTGKPFFQGR---------DEISQLEVI---YDMMGTPDVHSWPEV 503
>7290565 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 353
Score = 80.5 bits (197), Expect = 3e-15
Identities = 41/134 (30%), Positives = 73/134 (53%), Gaps = 14/134 (10%)
Query: 122 IEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAP 181
++GL Y+H N I+HRD+KP N+++NS + +GDFG++ + N T T Y++P
Sbjct: 122 LKGLEYLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSP 181
Query: 182 ELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDF-DECSDIKLVLTLFDK 240
ELLF Y +D+WA+ ++++L ++ + F SD+ + +F
Sbjct: 182 ELLFGARQYGTGVDMWAVGCILAEL-------------MLRVPFMPGDSDLDQLTRIFST 228
Query: 241 FGKPSNEDWPQVTK 254
G P+ +WP ++K
Sbjct: 229 LGTPTEAEWPHLSK 242
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 79.3 bits (194), Expect = 7e-15
Identities = 61/208 (29%), Positives = 98/208 (46%), Gaps = 25/208 (12%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD-NEAKT 170
DH V + QI+ GL Y+H GI+HRD+KP N+++NS + + DFG++ LD + T
Sbjct: 227 DHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMT 286
Query: 171 CDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSD 230
+ T Y+APE+L +Y IDIW++ + ++L + I F S
Sbjct: 287 QEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELLGRR------------ILFQAQSP 334
Query: 231 IKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLHRRPIDEQLIQVYKWMPLI 290
I+ + + D G PS E + + + G H++P L +Y
Sbjct: 335 IQQLDLITDLLGTPSLEAMRTACEGAKAHILRGP-------HKQP---SLPVLYTLSSQA 384
Query: 291 TDNPKLAKMWLRMVKFDGNLRISAEQLL 318
T + + RM+ FD + RISA+ L
Sbjct: 385 TH--EAVHLLCRMLVFDPSKRISAKDAL 410
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 78.6 bits (192), Expect = 1e-14
Identities = 56/183 (30%), Positives = 89/183 (48%), Gaps = 22/183 (12%)
Query: 27 VVKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCD-LNQFM 85
VV+ D++ ++ +E+ I L N +V+ + S S YV + + L+ +
Sbjct: 69 VVRLKDIKSRKVHEKLESEIAIHSKLDNPNVVKMYRSFRSSEYVFMVLELCERGALDALL 128
Query: 86 DQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGN-GIIHRDVKPQNIM 144
++ K K H ++Q +EGL+Y+H + ++HRD+K N+
Sbjct: 129 KRNGKLKER------------------HVARFVKQTVEGLIYLHNSVSVVHRDLKLGNLF 170
Query: 145 LNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLF-SVSNYKFEIDIWALAVLI 203
L+S V +GDFG+S D E K C T Y APE+LF S + FE DIW+L V+I
Sbjct: 171 LDSKFNVKIGDFGLSAVIK-DGEKKVTMCGTPNYIAPEVLFGKASGHSFEADIWSLGVII 229
Query: 204 SQL 206
L
Sbjct: 230 YTL 232
>At1g76540 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 313
Score = 78.6 bits (192), Expect = 1e-14
Identities = 52/222 (23%), Positives = 105/222 (46%), Gaps = 33/222 (14%)
Query: 39 PHNAHTELEILKTLS-NKHVIPLLG-----SETSPRYVTFKFKRYQCDLNQFMDQHWKAK 92
P E+ IL+ L+ + HV+ L+ S+ + F+ D+ +F+
Sbjct: 55 PSTTLREISILRMLARDPHVVRLMDVKQGLSKEGKTVLYLVFEYMDTDVKKFI------- 107
Query: 93 YNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYN-EV 151
S ++ IP ++ Q+ +G+ + HG+GI+HRD+KP N++++ +
Sbjct: 108 -------RSFRSTGKNIPTQTIKSLMYQLCKGMAFCHGHGILHRDLKPHNLLMDPKTMRL 160
Query: 152 VLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKT 211
+ D G++ L + T + T Y+APE+L ++Y +D+W++ + ++L ++
Sbjct: 161 KIADLGLARAFTLPMKKYTHEILTLWYRAPEVLLGATHYSTAVDMWSVGCIFAELVTNQA 220
Query: 212 QXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVT 253
F S+++ +L +F FG P+ E WP V+
Sbjct: 221 ------------IFQGDSELQQLLHIFKLFGTPNEEMWPGVS 250
>Hs20128774 [T] KOG0660 Mitogen-activated protein kinase
Length = 364
Score = 78.2 bits (191), Expect = 2e-14
Identities = 57/194 (29%), Positives = 95/194 (48%), Gaps = 18/194 (9%)
Query: 19 DLELFPDIVVKRIDLELQRPPHNAHT--ELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L + VK++ Q H T EL +LK L +++VI LL T
Sbjct: 43 DARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPAT-------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHR 136
+ F + + L+N K + + +H ++ Q++ GL YIH GIIHR
Sbjct: 95 ---SIEDFSEVYLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQLLRGLKYIHSAGIIHR 149
Query: 137 DVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDI 196
D+KP N+ +N E+ + DFG++ R D E T +T Y+APE++ + +Y +DI
Sbjct: 150 DLKPSNVAVNEDCELRILDFGLA--RQADEE-MTGYVATRWYRAPEIMLNWMHYNQTVDI 206
Query: 197 WALAVLISQLWNDK 210
W++ ++++L K
Sbjct: 207 WSVGCIMAELLQGK 220
>At1g59580 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 78.2 bits (191), Expect = 2e-14
Identities = 49/171 (28%), Positives = 86/171 (49%), Gaps = 23/171 (13%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFK-----FKRYQCDLNQFMDQHWKAKYNPYLLD 99
EL++L+ L +++V+ L + +FK ++ DL+Q +
Sbjct: 79 ELKLLRHLRHENVVALKDVMMANHKRSFKDVYLVYELMDTDLHQII-------------- 124
Query: 100 NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS 159
S++ SN DH + Q++ GL YIH I+HRD+KP N+++N+ ++ + DFG++
Sbjct: 125 KSSQVLSN----DHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLA 180
Query: 160 YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
N + T T Y+APELL NY ID+W++ + ++L K
Sbjct: 181 RTSNTKGQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRK 231
>At1g10210 [T] KOG0660 Mitogen-activated protein kinase
Length = 370
Score = 78.2 bits (191), Expect = 2e-14
Identities = 50/171 (29%), Positives = 86/171 (50%), Gaps = 23/171 (13%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFK-----FKRYQCDLNQFMDQHWKAKYNPYLLD 99
EL++L+ L +++VI L ++FK ++ DL+Q +
Sbjct: 79 ELKLLRHLRHENVIALKDVMMPIHKMSFKDVYLVYELMDTDLHQII-------------- 124
Query: 100 NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS 159
S++ SN DH + Q++ GL YIH I+HRD+KP N+++N+ ++ + DFG++
Sbjct: 125 KSSQVLSN----DHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLA 180
Query: 160 YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
N + T T Y+APELL NY ID+W++ + ++L K
Sbjct: 181 RASNTKGQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAELLGRK 231
>7296451 [D] KOG0600 Cdc2-related protein kinase
Length = 1157
Score = 78.2 bits (191), Expect = 2e-14
Identities = 75/301 (24%), Positives = 141/301 (45%), Gaps = 41/301 (13%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPLLGSETSPR-YVTFKFKRYQCDLN 82
+ +K++ LE ++ P A E++IL+ L++++++ L T + V F+ + L
Sbjct: 830 VALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHEIVTDKQDAVEFRKDKGSFYLV 889
Query: 83 -QFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQ 141
++MD LL++ ++ +++ I++Q+++GL Y H +HRD+K
Sbjct: 890 FEYMDHDLMG-----LLESGMVDFNE----ENNASIMKQLLDGLNYCHKKNFLHRDIKCS 940
Query: 142 NIMLNSYNEVVLGDFGISYNRNLDNEAK--TCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
NI++N+ +V L DFG++ N D+ + T T Y+ PELL Y ID+W+
Sbjct: 941 NILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSC 1000
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
++ +L+ + F +++ + T+ G P WP V K F+
Sbjct: 1001 GCILGELFVKRPL------------FQANAEMAQLETISKICGSPVPAVWPNVIKLPLFH 1048
Query: 260 GMFGNVSSDNFLHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLLV 319
+ HRR + E +++MP P L + +M+ D + RI+AE L
Sbjct: 1049 TL-----KQKKTHRRRLRED----FEFMPA----PAL-DLLDKMLDLDPDKRITAEDALR 1094
Query: 320 S 320
S
Sbjct: 1095 S 1095
>Hs7706549 [D] KOG0600 Cdc2-related protein kinase
Length = 1490
Score = 77.8 bits (190), Expect = 2e-14
Identities = 66/236 (27%), Positives = 108/236 (44%), Gaps = 26/236 (11%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPR-YVTFKFKRYQCDLN-QFMDQ 87
R+D E + P A E++IL+ L ++ V+ + T + + FK + L ++MD
Sbjct: 759 RLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDH 818
Query: 88 HWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNS 147
LL++ +S DH ++Q++EGL Y H +HRD+K NI+LN+
Sbjct: 819 DLMG-----LLESGLVHFSE----DHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNN 869
Query: 148 YNEVVLGDFGIS--YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQ 205
++ L DFG++ YN ++ T T Y+ PELL Y ID+W+ ++ +
Sbjct: 870 SGQIKLADFGLARLYNSE-ESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGE 928
Query: 206 LWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGM 261
L+ K E + ++L+ L G P WP V K FN M
Sbjct: 929 LFTKKPIFQANL---------ELAQLELISRL---CGSPCPAVWPDVIKLPYFNTM 972
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 77.8 bits (190), Expect = 2e-14
Identities = 57/208 (27%), Positives = 93/208 (44%), Gaps = 23/208 (11%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYN-RNLDNEAKT 170
DH V + QI+ GL Y+H I+HRD+KP N+++NS + + DFG++ D T
Sbjct: 144 DHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMT 203
Query: 171 CDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSD 230
+ T Y+APELL Y +DIW++ + ++L K I F
Sbjct: 204 HEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRK------------ILFQAAGP 251
Query: 231 IKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLHRRPIDEQLIQVYKWMPLI 290
I+ + + D G PS E + + + + R P ++L YK
Sbjct: 252 IEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGL-------RAPDTQRL---YKIASPD 301
Query: 291 TDNPKLAKMWLRMVKFDGNLRISAEQLL 318
N + + +++ FD + RIS E+ L
Sbjct: 302 DKNHEAVDLLQKLLHFDPDKRISVEEAL 329
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 77.8 bits (190), Expect = 2e-14
Identities = 57/208 (27%), Positives = 93/208 (44%), Gaps = 23/208 (11%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYN-RNLDNEAKT 170
DH V + QI+ GL Y+H I+HRD+KP N+++NS + + DFG++ D T
Sbjct: 169 DHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMT 228
Query: 171 CDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSD 230
+ T Y+APELL Y +DIW++ + ++L K I F
Sbjct: 229 HEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRK------------ILFQAAGP 276
Query: 231 IKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLHRRPIDEQLIQVYKWMPLI 290
I+ + + D G PS E + + + + R P ++L YK
Sbjct: 277 IEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGL-------RAPDTQRL---YKIASPD 326
Query: 291 TDNPKLAKMWLRMVKFDGNLRISAEQLL 318
N + + +++ FD + RIS E+ L
Sbjct: 327 DKNHEAVDLLQKLLHFDPDKRISVEEAL 354
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 77.8 bits (190), Expect = 2e-14
Identities = 57/208 (27%), Positives = 93/208 (44%), Gaps = 23/208 (11%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYN-RNLDNEAKT 170
DH V + QI+ GL Y+H I+HRD+KP N+++NS + + DFG++ D T
Sbjct: 341 DHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMT 400
Query: 171 CDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSD 230
+ T Y+APELL Y +DIW++ + ++L K I F
Sbjct: 401 HEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRK------------ILFQAAGP 448
Query: 231 IKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLHRRPIDEQLIQVYKWMPLI 290
I+ + + D G PS E + + + + R P ++L YK
Sbjct: 449 IEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGL-------RAPDTQRL---YKIASPD 498
Query: 291 TDNPKLAKMWLRMVKFDGNLRISAEQLL 318
N + + +++ FD + RIS E+ L
Sbjct: 499 DKNHEAVDLLQKLLHFDPDKRISVEEAL 526
>At4g01370 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 77.8 bits (190), Expect = 2e-14
Identities = 47/161 (29%), Positives = 83/161 (51%), Gaps = 14/161 (8%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKT 104
E+++LK + +++VI + P+ F +L D H + N L D
Sbjct: 90 EIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMD-TDLHQIIRSNQPLTD----- 143
Query: 105 YSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNL 164
DH + Q++ GL Y+H ++HRD+KP N++LN+ ++ LGDFG++ ++
Sbjct: 144 -------DHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLARTKS- 195
Query: 165 DNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQ 205
+ + T T Y+APELL + S Y IDIW++ ++ +
Sbjct: 196 ETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGE 236
>7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 302
Score = 77.8 bits (190), Expect = 2e-14
Identities = 48/207 (23%), Positives = 95/207 (45%), Gaps = 15/207 (7%)
Query: 92 KYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEV 151
+Y P L N K+ N + Q+ +G+ Y+H G++HRD+KP N++++ + +
Sbjct: 86 EYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAYLHEAGLMHRDIKPANLLISDTDML 145
Query: 152 VLGDFGIS--YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWND 209
+ DFG++ Y ++ + ST Y+APE+LF Y +D+WA +++++
Sbjct: 146 KIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGSQKYGTGVDMWAAGCVVAEMLRG 205
Query: 210 KTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGM-FGNVSSD 268
F +DI+ + + G P WP++T ++ + F N
Sbjct: 206 VPL------------FAGTTDIEQLAIIIRTLGSPRLNQWPELTSLPDYSKIRFPNSVGI 253
Query: 269 NFLHRRPIDEQLIQVYKWMPLITDNPK 295
++ + P +++ L+ NPK
Sbjct: 254 HWDNLFPSCTHAVEINLVSNLVVYNPK 280
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 77.4 bits (189), Expect = 3e-14
Identities = 51/228 (22%), Positives = 105/228 (45%), Gaps = 24/228 (10%)
Query: 26 IVVKRIDLELQRP-PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQF 84
+ +K I L+ Q P A E +L+ L + +++ L +TF F+ + DL+++
Sbjct: 134 VALKEIKLQFQEGLPFTAIREASLLRNLRHANIVSLHDIFYQHHQLTFVFEYMKMDLSKY 193
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIM 144
++Q N Y LD+ +++ Q++ GL + H I+HRD+KPQN++
Sbjct: 194 LEQ------NVYGLDSID-----------IKLLLFQLLRGLDFCHRKKILHRDLKPQNLL 236
Query: 145 LNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLIS 204
L+ + L DFG++ +++ + + + T Y+ P++L ++Y +D+W + + +
Sbjct: 237 LDEDGVLKLADFGLARAKSVPSRTYSHEVVTLWYRPPDVLMGSTDYSTSLDMWGVGCIFA 296
Query: 205 QLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQV 252
++ D+ +F G P + WP+V
Sbjct: 297 EICTGAALFPGSKDSHYPGTKDQLD------MIFSIRGTPDEKKWPEV 338
>CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 406
Score = 77.4 bits (189), Expect = 3e-14
Identities = 73/292 (25%), Positives = 128/292 (43%), Gaps = 63/292 (21%)
Query: 39 PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCD-------LNQFMDQ-HWK 90
P + E+ ++K L+ K P ++ K +Q D +N M++ W
Sbjct: 143 PQSVLREITVMKHLARK---------AHPNIISLKSVFHQLDPVRAILKINMIMERCDWD 193
Query: 91 AKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNE 150
L + +P + + QI+ L ++H + IIHRD+KPQNI+LN
Sbjct: 194 -------LHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTHSIIHRDLKPQNILLNRDQT 246
Query: 151 VVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
V L DFG+S + + A T T Y++PE+L S Y +D+WAL ++S+++ +
Sbjct: 247 VKLADFGLSKEYS-NTTAFTTLVVTLWYRSPEVLLQ-SYYNSTVDMWALGCIVSEIYCRQ 304
Query: 211 TQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNF 270
F ++ + + +F K G P +DWP +ES ++ D+F
Sbjct: 305 PL------------FVGQNEAEQLTDIFKKMGTPVGKDWP----SESV------IARDSF 342
Query: 271 LHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMV----KFDGNLRISAEQLL 318
RP + L +P+++K + V ++D + R+SA L
Sbjct: 343 PQYRPTN-----------LKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGAL 383
>CE26422 [D] KOG0600 Cdc2-related protein kinase
Length = 684
Score = 77.4 bits (189), Expect = 3e-14
Identities = 60/245 (24%), Positives = 115/245 (46%), Gaps = 38/245 (15%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ +KR+ LE ++ P A E++IL+ L +K+++ L+ D++
Sbjct: 337 VALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIVID-------------DIS- 382
Query: 84 FMDQHWKAKYNPYLL----DNSTKTYSNTIPL-----DHSTVIIRQIIEGLVYIHGNGII 134
MD+ + + N YL+ D+ + L D + +Q++EGL YIH G +
Sbjct: 383 -MDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFL 441
Query: 135 HRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEI 194
HRD+K NI++N+ E+ + D G++ ++ T T Y+ PELL Y I
Sbjct: 442 HRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNRVITLWYRPPELLLGDERYGPAI 501
Query: 195 DIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTK 254
D+W+ ++ +L+ K +E ++L+ + G P+ ++WP++T+
Sbjct: 502 DVWSTGCMLGELFTRKPLFNGN---------NEFGQLELISKV---CGSPNVDNWPELTE 549
Query: 255 NESFN 259
+N
Sbjct: 550 LVGWN 554
>CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 342
Score = 77.4 bits (189), Expect = 3e-14
Identities = 73/292 (25%), Positives = 128/292 (43%), Gaps = 63/292 (21%)
Query: 39 PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCD-------LNQFMDQ-HWK 90
P + E+ ++K L+ K P ++ K +Q D +N M++ W
Sbjct: 79 PQSVLREITVMKHLARK---------AHPNIISLKSVFHQLDPVRAILKINMIMERCDWD 129
Query: 91 AKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNE 150
L + +P + + QI+ L ++H + IIHRD+KPQNI+LN
Sbjct: 130 -------LHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTHSIIHRDLKPQNILLNRDQT 182
Query: 151 VVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
V L DFG+S + + A T T Y++PE+L S Y +D+WAL ++S+++ +
Sbjct: 183 VKLADFGLSKEYS-NTTAFTTLVVTLWYRSPEVLLQ-SYYNSTVDMWALGCIVSEIYCRQ 240
Query: 211 TQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNF 270
F ++ + + +F K G P +DWP +ES ++ D+F
Sbjct: 241 PL------------FVGQNEAEQLTDIFKKMGTPVGKDWP----SESV------IARDSF 278
Query: 271 LHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMV----KFDGNLRISAEQLL 318
RP + L +P+++K + V ++D + R+SA L
Sbjct: 279 PQYRPTN-----------LKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGAL 319
>At4g11330 [T] KOG0660 Mitogen-activated protein kinase
Length = 373
Score = 77.4 bits (189), Expect = 3e-14
Identities = 54/195 (27%), Positives = 94/195 (47%), Gaps = 26/195 (13%)
Query: 19 DLELFPDIVVKRIDLELQRPPHNAHT--ELEILKTLSNKHVIPLLGSETSPRYVTFK--- 73
D E +I +K+I T E+++L+ L +++V+ + P+ F
Sbjct: 59 DSETHEEIAIKKIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVY 118
Query: 74 --FKRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGN 131
F+ DL+Q + + N L D DH + QI+ GL YIH
Sbjct: 119 IVFELMDTDLHQII------RSNQSLND------------DHCQYFLYQILRGLKYIHSA 160
Query: 132 GIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYK 191
++HRD+KP N++LNS ++ + DFG++ + + E T T Y+APELL + S Y
Sbjct: 161 NVLHRDLKPSNLLLNSNCDLKITDFGLARTTS-ETEYMTEYVVTRWYRAPELLLNSSEYT 219
Query: 192 FEIDIWALAVLISQL 206
ID+W++ + +++
Sbjct: 220 SAIDVWSVGCIFAEI 234
>YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 306
Score = 77.0 bits (188), Expect = 3e-14
Identities = 40/139 (28%), Positives = 74/139 (52%), Gaps = 14/139 (10%)
Query: 122 IEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAP 181
+ G+ + H N I+HRD+KP N++ + ++ + DFG++ +E T + T Y+AP
Sbjct: 114 LRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAP 173
Query: 182 ELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDF-DECSDIKLVLTLFDK 240
ELLF +Y IDIW++ V+ ++L ++ I + +D+ + F
Sbjct: 174 ELLFGAKHYTSAIDIWSVGVIFAEL-------------MLRIPYLPGQNDVDQMEVTFRA 220
Query: 241 FGKPSNEDWPQVTKNESFN 259
G P++ DWP+V+ ++N
Sbjct: 221 LGTPTDRDWPEVSSFMTYN 239
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 77.0 bits (188), Expect = 3e-14
Identities = 41/136 (30%), Positives = 72/136 (52%), Gaps = 15/136 (11%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCD-CST 175
I+ QI++GL +IH +G HRD+KP+N++ V + DFG++ R + ++ D ST
Sbjct: 105 IMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLA--REIRSKPPYTDYVST 162
Query: 176 SIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVL 235
Y+APE+L +NY ID+WA+ ++++++ + F S+I +
Sbjct: 163 RWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPL------------FPGASEIDTIF 210
Query: 236 TLFDKFGKPSNEDWPQ 251
+ G P DWP+
Sbjct: 211 KICQVLGTPKKTDWPE 226
>CE06686 [T] KOG0660 Mitogen-activated protein kinase
Length = 377
Score = 77.0 bits (188), Expect = 3e-14
Identities = 55/188 (29%), Positives = 94/188 (49%), Gaps = 18/188 (9%)
Query: 26 IVVKRIDLELQRPPHNAHT--ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ +K+ + Q H T EL +L+ + ++++I LL T V N
Sbjct: 61 VAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENV-----------ND 109
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
D ++ + L N K + DH ++ QI+ GL YIH IIHRD+KP NI
Sbjct: 110 IEDVYFVSMLMGADLSNILKI--QRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNI 167
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
+N E+ + DFG++ R D+E T +T Y+APE++ + +Y +D+W++ ++
Sbjct: 168 AVNEDCELKILDFGLA--RQTDSE-MTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCIL 224
Query: 204 SQLWNDKT 211
++L KT
Sbjct: 225 AELITGKT 232
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 76.6 bits (187), Expect = 4e-14
Identities = 56/176 (31%), Positives = 82/176 (45%), Gaps = 19/176 (10%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTS 176
++ QI+ L Y+H +IHRD+K NIML+ N V +GDFG++ D E K C T
Sbjct: 143 LMMQILGALKYMHKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEERKMTICGTP 202
Query: 177 IYKAPELLF-SVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVI-------------D 222
Y APE+LF S + FE+D+W+ V++ L K I +
Sbjct: 203 NYIAPEILFNSKEGHSFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSN 262
Query: 223 IDFD-ECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN-GMFGNVSSDNFLHRRPI 276
+D E D+ L D +PS +D + +E F+ G + D LH PI
Sbjct: 263 VDISAEAKDLISSLLTHDPSIRPSIDD---IVDHEFFHTGYMASTLPDEILHSMPI 315
>At5g64960 [D] KOG0600 Cdc2-related protein kinase
Length = 513
Score = 76.6 bits (187), Expect = 4e-14
Identities = 67/291 (23%), Positives = 133/291 (45%), Gaps = 30/291 (10%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHW 89
R+D E + P A E++ILK L +++VI L TSP + + + D N++ +
Sbjct: 58 RMDNEREGFPITAIREIKILKKLHHENVIHLKEIVTSPG--RDRDDQGKPDNNKYKGGIY 115
Query: 90 KA-KYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSY 148
+Y + L + ++Q++ GL Y H N ++HRD+K N+++++
Sbjct: 116 MVFEYMDHDLTGLADRPGLRFTVPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNE 175
Query: 149 NEVVLGDFGISYNRNLDNEAK-TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLW 207
+ L DFG++ + + D+ T T Y+ PELL + Y ID+W++ + ++L
Sbjct: 176 GNLKLADFGLARSYSHDHTGNLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELL 235
Query: 208 NDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSS 267
N K ++ + + +++ G P +WP V+K +N M +
Sbjct: 236 NGKPILPGK------------TENEQLNKIYELCGSPDESNWPGVSKMPWYNQMKSS--- 280
Query: 268 DNFLHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
RP+ ++ ++Y+ + ++ +M+ D + RI A+ L
Sbjct: 281 ------RPLKRRVREIYRHF-----DRHALELLEKMLVLDPSQRICAKDAL 320
>7301110 [T] KOG0660 Mitogen-activated protein kinase
Length = 366
Score = 76.6 bits (187), Expect = 4e-14
Identities = 58/197 (29%), Positives = 96/197 (48%), Gaps = 33/197 (16%)
Query: 26 IVVKRIDLELQRPPHNAHT--ELEILKTLSNKHVIPLL---------GSETSPRYVTFKF 74
+ +K++ Q H T EL +LK + +++VI LL GS + + V
Sbjct: 51 VAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVT 110
Query: 75 KRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGII 134
DLN + +L D DH ++ QI+ GL YIH G+I
Sbjct: 111 HLMDADLNNIIRMQ-------HLSD------------DHVQFLVYQILRGLKYIHSAGVI 151
Query: 135 HRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEI 194
HRD+KP NI +N E+ + DFG++ R +NE T +T Y+APE++ + +Y +
Sbjct: 152 HRDLKPSNIAVNEDCELRILDFGLA--RPTENE-MTGYVATRWYRAPEIMLNWMHYDQTV 208
Query: 195 DIWALAVLISQLWNDKT 211
DIW++ ++++L +T
Sbjct: 209 DIWSVGCIMAELITRRT 225
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 76.6 bits (187), Expect = 4e-14
Identities = 55/241 (22%), Positives = 109/241 (44%), Gaps = 33/241 (13%)
Query: 26 IVVKRIDLEL--QRPPHNAHTELEILKTLSNKHVIPL--LGSETSPRYVTFKFKRYQCDL 81
+ +K+I LE + P A E+ +LK L +++++ L + E + Y+ F+F DL
Sbjct: 30 VAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLEDVLMEENRIYLIFEF--LSMDL 87
Query: 82 NQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQ 141
++MD + ++ ++Y + QI +++ H ++HRD+KPQ
Sbjct: 88 KKYMDS---LPVDKHMESELVRSY------------LYQITSAILFCHRRRVLHRDLKPQ 132
Query: 142 NIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAV 201
N++++ + + DFG+ + + T + T Y+APE+L Y +DIW++
Sbjct: 133 NLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGC 192
Query: 202 LISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGM 261
+ +++ K F S+I + +F P+ + WP VT +
Sbjct: 193 IFAEMATRKPL------------FQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNT 240
Query: 262 F 262
F
Sbjct: 241 F 241
>HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 76.3 bits (186), Expect = 6e-14
Identities = 53/186 (28%), Positives = 87/186 (46%), Gaps = 18/186 (9%)
Query: 21 ELFPDIVVKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCD 80
E+F +V + L E+ I ++L+++HV+ G +V + C
Sbjct: 77 EVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLEL--CR 134
Query: 81 LNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKP 140
++ H + K L + + Y +RQI+ G Y+H N +IHRD+K
Sbjct: 135 RRSLLEPHKRRKA---LTEPEARYY------------LRQIVLGCQYLHRNRVIHRDLKL 179
Query: 141 QNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALA 200
N+ LN EV +GDFG++ D E K C T Y APE+L S + FE+D+W++
Sbjct: 180 GNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVL-SKKEHSFEVDVWSIG 238
Query: 201 VLISQL 206
++ L
Sbjct: 239 CIMYTL 244
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 76.3 bits (186), Expect = 6e-14
Identities = 56/208 (26%), Positives = 97/208 (45%), Gaps = 32/208 (15%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKT 104
E++ LK L++ +VI L ++ F F+ + +L Q M K
Sbjct: 50 EVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLM-----------------KD 92
Query: 105 YSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNL 164
+ P I+ QI++GL +IH +G HRD+KP+N++ V + DFG++ R L
Sbjct: 93 RNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLA--REL 150
Query: 165 DNEAKTCD-CSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDI 223
++ D ST Y+APE+L S Y ID+WA+ ++++L+ ++
Sbjct: 151 RSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELY------------MLRP 198
Query: 224 DFDECSDIKLVLTLFDKFGKPSNEDWPQ 251
F S++ + + G P DWP+
Sbjct: 199 LFPGTSEVDEIFKICQVLGTPKKSDWPE 226
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 76.3 bits (186), Expect = 6e-14
Identities = 38/106 (35%), Positives = 62/106 (57%), Gaps = 1/106 (0%)
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD 165
+ T+ DH + QI+ GL YIH ++HRD+KP N++LN+ ++ + DFG++ N +
Sbjct: 128 TQTLTDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLNTNCDLKICDFGLARTSN-E 186
Query: 166 NEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKT 211
E T T Y+APELL + S Y IDIW++ + ++ +T
Sbjct: 187 TEIMTEYVVTRWYRAPELLLNSSEYTGAIDIWSVGCIFMEILRRET 232
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 76.3 bits (186), Expect = 6e-14
Identities = 49/198 (24%), Positives = 91/198 (45%), Gaps = 20/198 (10%)
Query: 54 NKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDH 113
N + L + P V K + D F+ ++ K + D T +P
Sbjct: 47 NLREVKSLKKLSHPNIVKLKEVIRENDTLYFVFEYMKENLYQMIKDRDTH-----LPEPE 101
Query: 114 STVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCD- 172
I+ Q++ GL ++H +G HRD+KP+N++ + + + + DFG++ R + + D
Sbjct: 102 LKSILFQVLTGLAFMHRHGFFHRDLKPENLLCSGPDLIKIADFGLA--REIRSRPPFTDY 159
Query: 173 CSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIK 232
ST Y+APE+L +NY ID+WA+ ++++L+ + F S++
Sbjct: 160 VSTRWYRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFRPL------------FPGSSEVD 207
Query: 233 LVLTLFDKFGKPSNEDWP 250
+ + G P +DWP
Sbjct: 208 QLFKICSVLGTPDKDDWP 225
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 76.3 bits (186), Expect = 6e-14
Identities = 51/166 (30%), Positives = 87/166 (51%), Gaps = 16/166 (9%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKT 104
EL+I++ L + +++ LL + + KR + LN ++ Y P + +
Sbjct: 589 ELQIMRKLEHCNIVKLLYF-----FYSSGEKRDEVFLNLVLE------YIPETVYKVARQ 637
Query: 105 YSNT---IPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV-LGDFGISY 160
Y+ T IP++ + + Q+ L YIH GI HRD+KPQN++L+ V+ L DFG S
Sbjct: 638 YAKTKQTIPINFIRLYMYQLFRSLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFG-SA 696
Query: 161 NRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ L E + Y+APEL+F NY +ID+W+ ++++L
Sbjct: 697 KQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAEL 742
>SPAC23H4.17c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 352
Score = 75.9 bits (185), Expect = 7e-14
Identities = 67/288 (23%), Positives = 127/288 (43%), Gaps = 40/288 (13%)
Query: 41 NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDN 100
+A E+ + + + +++++ L+ ++ F+ + DL Q + H +++
Sbjct: 57 SAIREMMLCREIQHENIVSLVQVLLKDGTISMVFEYAEHDLLQIIHFHSRSR-------- 108
Query: 101 STKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS- 159
+ IP I+ QII G+ Y+H N I+HRD+KP NIM+ + +V +GD G+
Sbjct: 109 -----TRQIPPSILKSILWQIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGR 163
Query: 160 --YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXX 217
+ L + T Y+APELL +Y ID+WA+ + ++
Sbjct: 164 LIRDPILPFYSSDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEM--------LAL 215
Query: 218 XXVIDIDFDECSDIKLV-------LTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNF 270
+ D + D K+V L + + G P+ E WP + + +SS
Sbjct: 216 SPLFKGDEIKMEDKKVVPFQSTQMLRIMELLGTPTEERWPGLKNYPEYY----QLSSFEV 271
Query: 271 LHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
+ + Q Q K +P+ + ++M+++D RI+A+Q L
Sbjct: 272 RYWNNLLPQWYQTVK-----NRDPQGLDLLMKMLQYDPKSRITAKQAL 314
>Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 326
Score = 75.9 bits (185), Expect = 7e-14
Identities = 45/159 (28%), Positives = 83/159 (51%), Gaps = 19/159 (11%)
Query: 98 LDNSTKTYSNTIP---LDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV 152
+D TY + +P + T+ ++ Q++ GL ++H + ++HRD+KPQNI++ S ++
Sbjct: 101 VDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIK 160
Query: 153 LGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQ 212
L DFG++ + A T T Y+APE+L S+Y +D+W++ + ++++ K
Sbjct: 161 LADFGLARIYSF-QMALTSVVVTLWYRAPEVLLQ-SSYATPVDLWSVGCIFAEMFRRKPL 218
Query: 213 XXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQ 251
F SD+ + + D G P EDWP+
Sbjct: 219 ------------FRGSSDVDQLGKILDVIGLPGEEDWPR 245
>Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 75.9 bits (185), Expect = 7e-14
Identities = 53/186 (28%), Positives = 87/186 (46%), Gaps = 18/186 (9%)
Query: 21 ELFPDIVVKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCD 80
E+F +V + L E+ I ++L+++HV+ G +V + C
Sbjct: 77 EVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLEL--CR 134
Query: 81 LNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKP 140
++ H + K L + + Y +RQI+ G Y+H N +IHRD+K
Sbjct: 135 RRSLLELHKRRKA---LTEPEARYY------------LRQIVLGCQYLHRNRVIHRDLKL 179
Query: 141 QNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALA 200
N+ LN EV +GDFG++ D E K C T Y APE+L S + FE+D+W++
Sbjct: 180 GNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVL-SKKGHSFEVDVWSIG 238
Query: 201 VLISQL 206
++ L
Sbjct: 239 CIMYTL 244
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 75.5 bits (184), Expect = 1e-13
Identities = 41/136 (30%), Positives = 71/136 (52%), Gaps = 15/136 (11%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCD-CST 175
I+ QI++GL +IH G HRD+KP+N++ V + DFG++ R + ++ D ST
Sbjct: 105 IMYQILQGLAFIHKLGFFHRDLKPENLLCMGPELVKIADFGLA--REIRSKPPYTDYVST 162
Query: 176 SIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVL 235
Y+APE+L +NY ID+WA+ ++++++ + F S+I +
Sbjct: 163 RWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPL------------FPGASEIDTIF 210
Query: 236 TLFDKFGKPSNEDWPQ 251
+ G P DWP+
Sbjct: 211 KICQVLGTPKKTDWPE 226
>CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 632
Score = 75.5 bits (184), Expect = 1e-13
Identities = 53/185 (28%), Positives = 88/185 (46%), Gaps = 23/185 (12%)
Query: 21 ELFPDIVVKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLG--SETSPRYVTFKFKRYQ 78
ELF VV + L Q E++I + L +++V+ L + S Y+T +
Sbjct: 60 ELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQHRNVVKLYHFFEDKSNVYITLEL---- 115
Query: 79 CDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDV 138
C M+ H + K + + QI+EG++Y+H I+HRD+
Sbjct: 116 CPRRSLMELHKRRK---------------AVTEPEARYFTYQIVEGVLYLHNLKIVHRDL 160
Query: 139 KPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWA 198
K N+ LN +V +GDFG++ + D KT C T Y APE+L + + FE+D+WA
Sbjct: 161 KLGNLFLNDELQVKIGDFGLATTCDNDERKKTL-CGTPNYIAPEVLNKI-GHSFEVDLWA 218
Query: 199 LAVLI 203
+ ++
Sbjct: 219 IGCIL 223
>At5g10270 [D] KOG0600 Cdc2-related protein kinase
Length = 505
Score = 75.5 bits (184), Expect = 1e-13
Identities = 69/291 (23%), Positives = 132/291 (44%), Gaps = 30/291 (10%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHW 89
R+D E + P A E++ILK L +++VI L TSP + + + D N++ +
Sbjct: 58 RMDNEREGFPITAIREIKILKKLHHENVIQLKEIVTSPG--RDRDDQGKPDNNKYKGGIY 115
Query: 90 KA-KYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSY 148
+Y + L + ++Q++ GL Y H N ++HRD+K N+++++
Sbjct: 116 MVFEYMDHDLTGLADRPGLRFTVPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNE 175
Query: 149 NEVVLGDFGISYNRNLDNEAK-TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLW 207
+ L DFG++ + + D+ T T Y+ PELL + Y ID+W++ + ++L
Sbjct: 176 GNLKLADFGLARSYSHDHTGNLTNRVITLWYRPPELLLGATKYGPAIDMWSVGCIFAELL 235
Query: 208 NDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSS 267
+ K ++ + + +F+ G P + WP V+K FN
Sbjct: 236 HAKPILPGK------------NEQEQLNKIFELCGSPDEKLWPGVSKMPWFN-------- 275
Query: 268 DNFLHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
NF RP+ ++ + ++ + ++ +M+ D RISA+ L
Sbjct: 276 -NFKPARPLKRRVREFFRHF-----DRHALELLEKMLVLDPAQRISAKDAL 320
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 75.5 bits (184), Expect = 1e-13
Identities = 46/168 (27%), Positives = 84/168 (49%), Gaps = 19/168 (11%)
Query: 40 HNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLD 99
H+ E+EIL+ L ++++I +L S + R + Q +L + ++
Sbjct: 48 HSLRQEIEILRKLKHENIIEMLDSFENAREFCVVTEFAQGELFEILED------------ 95
Query: 100 NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS 159
+P + I +Q+++ L Y+H N IIHRD+KPQNI++ + + V L DFG +
Sbjct: 96 ------DKCLPEEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNILIGAGSVVKLCDFGFA 149
Query: 160 YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLW 207
+ + T +Y APEL+ Y +D+W+L V++ +L+
Sbjct: 150 RAMSTNTVVLRSIKGTPLYMAPELV-KEQPYDRTVDLWSLGVILYELY 196
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 75.1 bits (183), Expect = 1e-13
Identities = 46/160 (28%), Positives = 84/160 (51%), Gaps = 7/160 (4%)
Query: 47 EILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYS 106
EI T+ ++++ S++SP V KF +Q + ++ + + + +S
Sbjct: 453 EIAHTIGERNILVTTASKSSPFIVGLKFS-FQTPTDLYLVTDYMSGGELFWHLQKEGRFS 511
Query: 107 NTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDN 166
D + I +++ L ++H N I++RD+KP+NI+L++ + L DFG+S +L +
Sbjct: 512 E----DRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLS-KADLKD 566
Query: 167 EAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
T C T+ Y APELL + Y +D W+L VLI ++
Sbjct: 567 RTNTF-CGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEM 605
>At1g20930 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 315
Score = 75.1 bits (183), Expect = 1e-13
Identities = 51/223 (22%), Positives = 105/223 (46%), Gaps = 33/223 (14%)
Query: 39 PHNAHTELEILKTLS-NKHVIPLLG-----SETSPRYVTFKFKRYQCDLNQFMDQHWKAK 92
P E+ IL+ L+ + H++ L+ ++ + F+ DL +F+ +A
Sbjct: 57 PPTTLREISILRMLARDPHIVRLMDVKQGINKEGKTVLYLVFEYVDTDLKKFIRSFRQAG 116
Query: 93 YNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV 152
N IP + ++ Q+ +G+ + HG+G++HRD+KP N++++ +
Sbjct: 117 QN--------------IPQNTVKCLMYQLCKGMAFCHGHGVLHRDLKPHNLLMDRKTMTL 162
Query: 153 -LGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKT 211
+ D G++ L + T + T Y+APE+L ++Y +D+W++ + ++L +
Sbjct: 163 KIADLGLARAFTLPMKKYTHEILTLWYRAPEVLLGATHYSTGVDMWSVGCIFAELVTKQA 222
Query: 212 QXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTK 254
F S+++ +L +F G P+ E WP V+K
Sbjct: 223 ------------IFAGDSELQQLLRIFRLLGTPNEEVWPGVSK 253
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 74.7 bits (182), Expect = 2e-13
Identities = 45/155 (29%), Positives = 81/155 (52%), Gaps = 17/155 (10%)
Query: 99 DNSTKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDF 156
D S + + + HS + +Q++ G+ Y+H N I+HRDVK NI++++ + + DF
Sbjct: 266 DLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDF 325
Query: 157 GISYNRNLDNEAK-TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXX 215
G++ R +++ A T T Y+ PELL +NY E+D+W L+ +L+N KT
Sbjct: 326 GLA--RKMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFN-KTAI-- 380
Query: 216 XXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWP 250
F ++++ + ++F G P+ WP
Sbjct: 381 ---------FQGSNELEQIESIFKIMGTPTINSWP 406
>At5g63370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 612
Score = 74.7 bits (182), Expect = 2e-13
Identities = 38/134 (28%), Positives = 69/134 (51%), Gaps = 12/134 (8%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTS 176
++ Q+++GL Y+H N IIHRD+KP N+++N+ E+ + DFG++ + T T
Sbjct: 406 LMMQLLDGLKYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQYGSPIKPYTQMVITQ 465
Query: 177 IYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLT 236
Y+ PELL Y +D+W++ ++++L + K F S++ +
Sbjct: 466 WYRPPELLLGAKEYSTAVDMWSVGCIMAELLSQKPL------------FPGKSELDQLQK 513
Query: 237 LFDKFGKPSNEDWP 250
+F G P+ WP
Sbjct: 514 IFAVLGTPNEAIWP 527
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 74.7 bits (182), Expect = 2e-13
Identities = 54/238 (22%), Positives = 114/238 (47%), Gaps = 40/238 (16%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNK-HVIPLL----------GSETSPRYVTFKFKRYQ 78
R++++ + P A E+ +L+ LS +V+ LL S+++ + F+
Sbjct: 36 RLEMDEEGIPPTALREISLLQMLSTSIYVVRLLCVEHVHQPSTKSQSTKSNLYLVFEYLD 95
Query: 79 CDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNGIIHR 136
DL +F+D + K N PL+ + ++ Q+ +G+ + H +G++HR
Sbjct: 96 TDLKKFIDSYRKGP--------------NPKPLEPFLIQKLMFQLCKGVAHCHSHGVLHR 141
Query: 137 DVKPQNIMLNSYNEVV-LGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
D+KPQN++L E++ + D G+ + ++ T + T Y+APE+L ++Y +D
Sbjct: 142 DLKPQNLLLVKDKELLKIADLGLGRAFTVPLKSYTHEIVTLWYRAPEVLLGSTHYSTGVD 201
Query: 196 IWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVT 253
+W++ + +++ + F S+ + +L +F G P+ + WP V+
Sbjct: 202 MWSVGCIFAEMVRRQAL------------FPGDSEFQQLLHIFRLLGTPTEQQWPGVS 247
>SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 398
Score = 74.3 bits (181), Expect = 2e-13
Identities = 50/217 (23%), Positives = 100/217 (46%), Gaps = 35/217 (16%)
Query: 39 PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYN 94
P + E+E L ++ + +++ L +G + Y+ +F + DL
Sbjct: 115 PITSLREIESLSSIRHDNIVELEKVVVGKDLKDVYLVMEFMEH--DLKT----------- 161
Query: 95 PYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLG 154
LLDN + + + ++ Q++ ++H + +HRD+KP N+++N+ E+ L
Sbjct: 162 --LLDNMPEDFLQS----EVKTLMLQLLAATAFMHHHWYLHRDLKPSNLLMNNTGEIKLA 215
Query: 155 DFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXX 214
DFG++ + + T T Y+APELL +Y EID+W++ + +++
Sbjct: 216 DFGLARPVSEPKSSLTRLVVTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMITRTPL-- 273
Query: 215 XXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQ 251
F S++ + +F+ G P+ E+WPQ
Sbjct: 274 ----------FSGKSELDQLYKIFNLLGYPTREEWPQ 300
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 74.3 bits (181), Expect = 2e-13
Identities = 48/163 (29%), Positives = 82/163 (49%), Gaps = 22/163 (13%)
Query: 44 TELEILKTLSNKHVIPLLG-SETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNST 102
TE+E LK L ++H+ L ET+ + F Y C + D Y++
Sbjct: 56 TEIEALKNLRHQHICQLYHVLETANK--IFMVLEY-CPGGELFD---------YIIS--- 100
Query: 103 KTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGI--SY 160
+ + + + V+ RQI+ + Y+H G HRD+KP+N++ + Y+++ L DFG+
Sbjct: 101 ---QDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKP 157
Query: 161 NRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
N D +TC C + Y APEL+ S E D+W++ +L+
Sbjct: 158 KGNKDYHLQTC-CGSLAYAAPELIQGKSYLGSEADVWSMGILL 199
>Hs4502735 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 303
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/161 (30%), Positives = 83/161 (51%), Gaps = 23/161 (14%)
Query: 98 LDNSTKTYSNTIP---LDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV 152
+D +TY + P L T+ ++RQ + GL ++H N I+HRD+KP+NI++ S V
Sbjct: 96 VDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVK 155
Query: 153 LGDFGIS--YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
L DFG++ Y+ + A T T Y+APE+L S Y +D+W++ + ++++ K
Sbjct: 156 LADFGLARIYSYQM---ALTPVVVTLWYRAPEVLLQ-STYATPVDMWSVGCIFAEMFRRK 211
Query: 211 TQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQ 251
F S+ + +FD G P +DWP+
Sbjct: 212 PL------------FCGNSEADQLGKIFDLIGLPPEDDWPR 240
>At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 348
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/183 (26%), Positives = 85/183 (45%), Gaps = 19/183 (10%)
Query: 26 IVVKRIDLELQRPPHN--AHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ VK+I L Q+ N A E+++LK L++ H++ L+ + + F+ Q DL
Sbjct: 39 VAVKKIRLGNQKEGVNFTALREIKLLKELNHPHIVELIDAFPHDGSLHLVFEYMQTDLEA 98
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
+ N +L K+Y + ++GL Y H ++HRD+KP N+
Sbjct: 99 VIRDR-----NIFLSPGDIKSY------------MLMTLKGLAYCHKKWVLHRDMKPNNL 141
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
++ + L DFG++ N T + Y+APELLF Y +D+WA +
Sbjct: 142 LIGENGLLKLADFGLARLFGSPNRRFTHQVFATWYRAPELLFGSRQYGAGVDVWAAGCIF 201
Query: 204 SQL 206
++L
Sbjct: 202 AEL 204
>Hs14110390 [D] KOG0600 Cdc2-related protein kinase
Length = 1452
Score = 73.9 bits (180), Expect = 3e-13
Identities = 74/293 (25%), Positives = 129/293 (43%), Gaps = 40/293 (13%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPR-YVTFKFKRYQCDLN-QFMDQ 87
R+D E + P A E++IL+ L+++ +I + T + FK + L ++MD
Sbjct: 737 RLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDH 796
Query: 88 HWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNS 147
LL++ ++ +H +RQ++EGL Y H +HRD+K NI+LN+
Sbjct: 797 DLMG-----LLESGLVHFNE----NHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNN 847
Query: 148 YNEVVLGDFGIS-YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
++ L DFG++ + ++ T T Y+ PELL Y ID+W+ ++ +L
Sbjct: 848 RGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGEL 907
Query: 207 WNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVS 266
+ K E + ++L+ + G P WP V K FN M
Sbjct: 908 FTKKPIFQAN---------QELAQLELISRI---CGSPCPAVWPDVIKLPYFNTM----- 950
Query: 267 SDNFLHRRPIDEQLIQVYKWMPLITDNPKLA-KMWLRMVKFDGNLRISAEQLL 318
+RR + E+ + + P A ++ M+ D + R +AEQ L
Sbjct: 951 KPKKQYRRKLREEFVFI----------PAAALDLFDYMLALDPSKRCTAEQAL 993
>Hs14110387 [D] KOG0600 Cdc2-related protein kinase
Length = 1512
Score = 73.9 bits (180), Expect = 3e-13
Identities = 74/293 (25%), Positives = 129/293 (43%), Gaps = 40/293 (13%)
Query: 30 RIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPR-YVTFKFKRYQCDLN-QFMDQ 87
R+D E + P A E++IL+ L+++ +I + T + FK + L ++MD
Sbjct: 737 RLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDH 796
Query: 88 HWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNS 147
LL++ ++ +H +RQ++EGL Y H +HRD+K NI+LN+
Sbjct: 797 DLMG-----LLESGLVHFNE----NHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNN 847
Query: 148 YNEVVLGDFGIS-YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
++ L DFG++ + ++ T T Y+ PELL Y ID+W+ ++ +L
Sbjct: 848 RGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGEL 907
Query: 207 WNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVS 266
+ K E + ++L+ + G P WP V K FN M
Sbjct: 908 FTKKPIFQAN---------QELAQLELISRI---CGSPCPAVWPDVIKLPYFNTM----- 950
Query: 267 SDNFLHRRPIDEQLIQVYKWMPLITDNPKLA-KMWLRMVKFDGNLRISAEQLL 318
+RR + E+ + + P A ++ M+ D + R +AEQ L
Sbjct: 951 KPKKQYRRKLREEFVFI----------PAAALDLFDYMLALDPSKRCTAEQAL 993
>ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 296
Score = 73.9 bits (180), Expect = 3e-13
Identities = 62/292 (21%), Positives = 122/292 (41%), Gaps = 44/292 (15%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQ 83
+ +K+I LE + P E+ +LK L + ++ L + + F+ + DL +
Sbjct: 31 VALKKIRLENENEGIPATTIREILLLKNLKHSTIVELSDVIYNNNKMYLVFEYVELDLRR 90
Query: 84 FMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNI 143
++D+ + D + + +Q++ + Y H I HRD+KPQNI
Sbjct: 91 YLDR---------MSDEGRLVEEGFV-----RKMSQQLLTAMEYCHSRNIFHRDLKPQNI 136
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
+++ + L DFG+ + T + T Y+ PELL Y +D+W+ A ++
Sbjct: 137 LVDPKENIKLADFGLGRAAGIPLRTYTTEVVTLWYRPPELLLGCKYYDASVDVWSAACIM 196
Query: 204 SQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFG 263
+++ ++ F S+I + +F G P+N W V F
Sbjct: 197 AEV------------VLMRPFFPGDSEIDQLFRIFKVLGTPNNSRWSNVEN-------FP 237
Query: 264 NVSSDNFLHRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAE 315
N + F P+D + I +P + +M+++D +R++A+
Sbjct: 238 NYKVE-FPVWDPVDLKTI--------FRGDPDFVDLISKMLEYDPKMRMTAK 280
>SPBPI064 [G] KOG0658 Glycogen synthase kinase-3
Length = 350
Score = 73.6 bits (179), Expect = 4e-13
Identities = 47/175 (26%), Positives = 90/175 (50%), Gaps = 22/175 (12%)
Query: 40 HNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFM------DQHWKAKY 93
H + EL+I++ +S+ ++I L+ + + K + + C L ++M D W +
Sbjct: 30 HRVNRELQIMRAISHPNIIKLIAFFHT--HNPSKDETHLCLLLEYMPETVFDDMRWYTRR 87
Query: 94 NPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV- 152
+ + S K Y+ Q+ L Y+H G+ HRD+KPQN++++ ++
Sbjct: 88 RKSIPNLSIKLYAF------------QLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILK 135
Query: 153 LGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLW 207
L DFG S + +E + Y+APEL+F ++Y +ID+W+ A +I++L+
Sbjct: 136 LCDFG-SAKVLVPSEPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELF 189
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 73.6 bits (179), Expect = 4e-13
Identities = 50/190 (26%), Positives = 91/190 (47%), Gaps = 27/190 (14%)
Query: 25 DIVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLN 82
++ VK+I P + EL++LK L ++++I L SP
Sbjct: 45 NVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENIISLSDIFISP--------------- 89
Query: 83 QFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNGIIHRDVKP 140
F D ++ + LL + PL+ + + QI+ GL ++H G+IHRD+KP
Sbjct: 90 -FEDIYFVTE----LLGTDLHRLLTSRPLETQFIQYFLYQILRGLKFVHSAGVIHRDLKP 144
Query: 141 QNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALA 200
NI++N ++ + DFG++ + + T ST Y+APE++ + Y E+DIW+
Sbjct: 145 SNILINENCDLKICDFGLA---RIQDPQMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAG 201
Query: 201 VLISQLWNDK 210
+ +++ K
Sbjct: 202 CIFAEMIEGK 211
>Hs16357498 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 73.6 bits (179), Expect = 4e-13
Identities = 54/231 (23%), Positives = 104/231 (44%), Gaps = 37/231 (16%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 446 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 503
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 504 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 546
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 547 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSV 606
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWP 250
+ +L K F S+I + +F + G PS + WP
Sbjct: 607 GCIFGELLTQKPL------------FPGNSEIDQINKVFKELGTPSEKIWP 645
>Hs16357486 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 73.6 bits (179), Expect = 4e-13
Identities = 54/231 (23%), Positives = 104/231 (44%), Gaps = 37/231 (16%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 449 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 506
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 507 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 549
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 550 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSV 609
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWP 250
+ +L K F S+I + +F + G PS + WP
Sbjct: 610 GCIFGELLTQKPL------------FPGNSEIDQINKVFKELGTPSEKIWP 648
>Hs16357484 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 767
Score = 73.6 bits (179), Expect = 4e-13
Identities = 54/231 (23%), Positives = 104/231 (44%), Gaps = 37/231 (16%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 436 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 493
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 494 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 536
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 537 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSV 596
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWP 250
+ +L K F S+I + +F + G PS + WP
Sbjct: 597 GCIFGELLTQKPL------------FPGNSEIDQINKVFKELGTPSEKIWP 635
>Hs16357482 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 776
Score = 73.6 bits (179), Expect = 4e-13
Identities = 54/231 (23%), Positives = 104/231 (44%), Gaps = 37/231 (16%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 445 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 502
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 503 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 545
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 546 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSV 605
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWP 250
+ +L K F S+I + +F + G PS + WP
Sbjct: 606 GCIFGELLTQKPL------------FPGNSEIDQINKVFKELGTPSEKIWP 644
>Hs16357480 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 397
Score = 73.6 bits (179), Expect = 4e-13
Identities = 54/231 (23%), Positives = 104/231 (44%), Gaps = 37/231 (16%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 66 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 123
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 124 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 166
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 167 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSV 226
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWP 250
+ +L K F S+I + +F + G PS + WP
Sbjct: 227 GCIFGELLTQKPL------------FPGNSEIDQINKVFKELGTPSEKIWP 265
>ECU11g0960 [D] KOG0600 Cdc2-related protein kinase
Length = 329
Score = 73.6 bits (179), Expect = 4e-13
Identities = 48/183 (26%), Positives = 87/183 (47%), Gaps = 25/183 (13%)
Query: 28 VKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPR---YVTFKFKRYQCDLNQF 84
+K++ E + E+++L+ + + ++ L+ P Y+ F + Y DLN+F
Sbjct: 48 LKKVSKEKEGLSVTTIREVQVLRAMGHPSIVRLIEVVVEPGGDIYMVFPYFPY--DLNRF 105
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIM 144
+ SN + I QI +G+ YIH GI+HRD+K NI+
Sbjct: 106 IR-------------------SNKMTCSEIKHIFYQIAQGVCYIHSKGIMHRDLKSANIL 146
Query: 145 LNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLIS 204
L+ + DFG++ A T T Y+APE+L S+Y + +DIW+L +++
Sbjct: 147 LDQKLNASIADFGMA-RYTTKTGAYTPGMVTLWYRAPEILLGSSSYTYAVDIWSLGCILT 205
Query: 205 QLW 207
+++
Sbjct: 206 EMY 208
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 73.6 bits (179), Expect = 4e-13
Identities = 49/168 (29%), Positives = 89/168 (52%), Gaps = 20/168 (11%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKF--KRYQCDLNQFMDQHWKAKYNPYLLDNST 102
EL+I++ L++ +++ L +Y + K+ + LN ++ Y P +
Sbjct: 77 ELQIMRKLNHPNIVKL-------KYFFYSSGEKKDELYLNLILE------YVPETVYRVA 123
Query: 103 KTYSNT---IPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV-LGDFGI 158
+ YS IP+ + + + Q++ L YIH GI HRD+KPQN++++ + V+ L DFG
Sbjct: 124 RHYSKQRQQIPMIYVKLYMYQLLRSLAYIHSIGICHRDIKPQNLLIDPESGVLKLCDFG- 182
Query: 159 SYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
S + NE + Y+APEL+F +NY ID+W+ ++++L
Sbjct: 183 SAKYLVRNEPNVSYICSRYYRAPELIFGATNYTNSIDVWSAGTVMAEL 230
>At1g67580 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 752
Score = 73.6 bits (179), Expect = 4e-13
Identities = 56/241 (23%), Positives = 106/241 (43%), Gaps = 49/241 (20%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +K++ +E +R P + E+ IL + + ++ + +GS ++ ++ +
Sbjct: 432 VALKKVKMEKEREGFPLTSLREINILLSFHHPSIVDVKEVVVGSSLDSIFMVMEYMEH-- 489
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ T ++ Q++EG+ Y+H N ++HRD+K
Sbjct: 490 DLKALME-----------------TMKQRFSQSEVKCLMLQLLEGVKYLHDNWVLHRDLK 532
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++LN+ E+ + DFG++ + T T Y+APELL Y ID+W+L
Sbjct: 533 TSNLLLNNRGELKICDFGLARQYGSPLKPYTHLVVTLWYRAPELLLGAKQYSTAIDMWSL 592
Query: 200 AVLISQ------LWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVT 253
++++ L+N KT +FD+ I +L G P+ WP +
Sbjct: 593 GCIMAELLMKAPLFNGKT------------EFDQLDKIFRIL------GTPNESIWPGFS 634
Query: 254 K 254
K
Sbjct: 635 K 635
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 73.6 bits (179), Expect = 4e-13
Identities = 37/89 (41%), Positives = 54/89 (60%), Gaps = 1/89 (1%)
Query: 118 IRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSI 177
I QII+G+ Y+H N IIHRD+K N+ LN V +GDFG++ + E K C T
Sbjct: 129 IYQIIQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERKKTLCGTPN 188
Query: 178 YKAPELLFSVSNYKFEIDIWALAVLISQL 206
Y APE+L + + FE+DIW++ ++ L
Sbjct: 189 YIAPEIL-TKKGHSFEVDIWSIGCVMYTL 216
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 73.2 bits (178), Expect = 5e-13
Identities = 36/105 (34%), Positives = 61/105 (57%), Gaps = 5/105 (4%)
Query: 108 TIPLDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD 165
T PL+ V + QI+ GL Y+H G+IHRD+KP NI++N ++ + DFG++ +
Sbjct: 113 TRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLA---RIQ 169
Query: 166 NEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
+ T ST Y+APE++ + Y E+DIW+ + +++ K
Sbjct: 170 DPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGK 214
>SPBC36B7.09 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 903
Score = 73.2 bits (178), Expect = 5e-13
Identities = 39/113 (34%), Positives = 64/113 (56%), Gaps = 15/113 (13%)
Query: 109 IPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS--------- 159
IP+D + RQI+E L YIH G++HRD+KP NI L+ V LGDFG++
Sbjct: 744 IPVDEMWRLFRQILEALAYIHSRGMMHRDLKPGNIFLDENRNVKLGDFGLATENENYQDN 803
Query: 160 ----YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFE--IDIWALAVLISQL 206
NR +E T T++Y APELL + +++ +D+++L +++ ++
Sbjct: 804 NDKWKNRQSADEDLTTGVGTALYVAPELLSRRNGVRYDAKVDMYSLGIILFEM 856
>Hs16357494 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 775
Score = 73.2 bits (178), Expect = 5e-13
Identities = 41/142 (28%), Positives = 72/142 (49%), Gaps = 13/142 (9%)
Query: 109 IPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEA 168
+P + T++I Q++ G+ ++H N I+HRD+K N++L+ + +GDFG++ +A
Sbjct: 515 LPGEVKTLMI-QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 573
Query: 169 KTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDEC 228
T T Y+APELL Y +D+W++ + +L K F
Sbjct: 574 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPL------------FPGN 621
Query: 229 SDIKLVLTLFDKFGKPSNEDWP 250
S+I + +F + G PS + WP
Sbjct: 622 SEIDQINKVFKELGTPSEKIWP 643
>Hs16357492 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 777
Score = 73.2 bits (178), Expect = 5e-13
Identities = 41/142 (28%), Positives = 72/142 (49%), Gaps = 13/142 (9%)
Query: 109 IPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEA 168
+P + T++I Q++ G+ ++H N I+HRD+K N++L+ + +GDFG++ +A
Sbjct: 517 LPGEVKTLMI-QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKA 575
Query: 169 KTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDEC 228
T T Y+APELL Y +D+W++ + +L K F
Sbjct: 576 YTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPL------------FPGN 623
Query: 229 SDIKLVLTLFDKFGKPSNEDWP 250
S+I + +F + G PS + WP
Sbjct: 624 SEIDQINKVFKELGTPSEKIWP 645
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 72.8 bits (177), Expect = 6e-13
Identities = 46/166 (27%), Positives = 88/166 (52%), Gaps = 16/166 (9%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKT 104
EL+I++ + + +++ L+ Y T + LN ++ + P + +++
Sbjct: 73 ELQIMRIMKHPNIVDLIAY-----YYTTGDNSDEVYLNLVLE------FMPETIYRASRL 121
Query: 105 YSN---TIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV-LGDFGISY 160
Y+ ++P+ + I Q++ L YIH +GI HRD+KPQN++L+ N ++ L DFG S
Sbjct: 122 YTRQKLSMPMLEVKLYIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFG-SA 180
Query: 161 NRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ E + Y+APEL+F ++Y IDIW+ ++++L
Sbjct: 181 KILVAGEPNVSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAEL 226
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 72.8 bits (177), Expect = 6e-13
Identities = 54/217 (24%), Positives = 103/217 (46%), Gaps = 30/217 (13%)
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD 165
S + DH + QI+ GL YIH ++HRD+KP N+++N+ ++ + DFG++ + +
Sbjct: 135 SQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPE 194
Query: 166 NEAK---TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVID 222
++ T +T Y+APE++ + Y IDIW++ +++++ +++
Sbjct: 195 HDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHY---- 250
Query: 223 IDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLHRRPIDEQLIQ 282
D+ + I +L G PS ED + N+ + N+L P ++
Sbjct: 251 --LDQLNHILGIL------GSPSQEDLNCII----------NMKARNYLQSLPSKTKV-- 290
Query: 283 VYKWMPLI-TDNPKLAKMWLRMVKFDGNLRISAEQLL 318
W L + K + RM+ F+ N RI+ E+ L
Sbjct: 291 --AWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEAL 325
>ECU08g1790 [D] KOG0600 Cdc2-related protein kinase
Length = 309
Score = 72.8 bits (177), Expect = 6e-13
Identities = 57/211 (27%), Positives = 100/211 (47%), Gaps = 37/211 (17%)
Query: 39 PHNAHTELEILKTLSNKHVIPL--LGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPY 96
P A E+++ K++ NKH+I L + E +V ++ Y DL
Sbjct: 44 PFTAIREIKLCKSVINKHIIGLDEIVFEEGFIFVVLEYMPY--DLTG------------- 88
Query: 97 LLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDF 156
LL + K + D I Q+IE + +HG G++HRD+KP NI+L+ + + L DF
Sbjct: 89 LLASGAK-----LSTDQIRSITSQLIEAVSSMHGMGLVHRDIKPSNILLDCHGMLKLTDF 143
Query: 157 GISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXX 216
G++ + + C T Y+APELL ++Y ++D W++ ++ ++ +
Sbjct: 144 GLTREISGMMTNRVC---TLWYRAPELLLGETSYSLKVDAWSVGCIMLEMRLGRPPYRGS 200
Query: 217 XXXVIDIDFDECSDIKLVLTLFDKFGKPSNE 247
DE S IKL+ F++ G P ++
Sbjct: 201 ---------DEVSQIKLI---FEELGIPQDK 219
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 72.4 bits (176), Expect = 8e-13
Identities = 50/168 (29%), Positives = 87/168 (51%), Gaps = 20/168 (11%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKF--KRYQCDLNQFMDQHWKAKYNPYLLDNST 102
EL+I++ L + +++ L RY + K+ + LN +D Y P +
Sbjct: 97 ELQIMRKLDHCNIVRL-------RYFFYSSGEKKDEVYLNLVLD------YVPETVYRVA 143
Query: 103 KTYSN---TIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV-LGDFGI 158
+ YS T+P+ + + + Q+ L YIH GI HRD+KPQN++L+ V+ L DFG
Sbjct: 144 RHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFG- 202
Query: 159 SYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
S + + E + Y+APEL+F ++Y ID+W+ ++++L
Sbjct: 203 SAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAEL 250
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 72.4 bits (176), Expect = 8e-13
Identities = 50/168 (29%), Positives = 87/168 (51%), Gaps = 20/168 (11%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKF--KRYQCDLNQFMDQHWKAKYNPYLLDNST 102
EL+I++ L + +++ L RY + K+ + LN +D Y P +
Sbjct: 97 ELQIMRKLDHCNIVRL-------RYFFYSSGEKKDEVYLNLVLD------YVPETVYRVA 143
Query: 103 KTYSN---TIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV-LGDFGI 158
+ YS T+P+ + + + Q+ L YIH GI HRD+KPQN++L+ V+ L DFG
Sbjct: 144 RHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFG- 202
Query: 159 SYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
S + + E + Y+APEL+F ++Y ID+W+ ++++L
Sbjct: 203 SAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAEL 250
>Hs16357496 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 439
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 37/255 (14%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 108 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 165
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 166 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 208
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 209 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 268
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +L K F S+I + +F G PS + WP ++ +
Sbjct: 269 GCIFGELLTQKPL------------FPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 316
Query: 260 GMFGNVSSDNFLHRR 274
M + N L +R
Sbjct: 317 KMTFSEHPYNNLRKR 331
>Hs16332372 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 771
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 37/255 (14%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 440 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 497
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 498 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 540
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 541 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 600
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +L K F S+I + +F G PS + WP ++ +
Sbjct: 601 GCIFGELLTQKPL------------FPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 648
Query: 260 GMFGNVSSDNFLHRR 274
M + N L +R
Sbjct: 649 KMTFSEHPYNNLRKR 663
>Hs16332370 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 780
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 37/255 (14%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 449 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 506
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 507 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 549
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 550 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 609
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +L K F S+I + +F G PS + WP ++ +
Sbjct: 610 GCIFGELLTQKPL------------FPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 657
Query: 260 GMFGNVSSDNFLHRR 274
M + N L +R
Sbjct: 658 KMTFSEHPYNNLRKR 672
>Hs16332368 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 461
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 37/255 (14%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 130 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 187
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 188 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 230
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 231 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 290
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +L K F S+I + +F G PS + WP ++ +
Sbjct: 291 GCIFGELLTQKPL------------FPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 338
Query: 260 GMFGNVSSDNFLHRR 274
M + N L +R
Sbjct: 339 KMTFSEHPYNNLRKR 353
>Hs16332366 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 565
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 37/255 (14%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 234 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 291
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 292 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 334
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 335 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 394
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +L K F S+I + +F G PS + WP ++ +
Sbjct: 395 GCIFGELLTQKPL------------FPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 442
Query: 260 GMFGNVSSDNFLHRR 274
M + N L +R
Sbjct: 443 KMTFSEHPYNNLRKR 457
>Hs16332364 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 748
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 37/255 (14%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 417 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 474
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 475 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 517
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 518 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 577
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +L K F S+I + +F G PS + WP ++ +
Sbjct: 578 GCIFGELLTQKPL------------FPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 625
Query: 260 GMFGNVSSDNFLHRR 274
M + N L +R
Sbjct: 626 KMTFSEHPYNNLRKR 640
>Hs16332362 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 737
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 37/255 (14%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 406 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 463
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 464 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 506
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 507 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 566
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +L K F S+I + +F G PS + WP ++ +
Sbjct: 567 GCIFGELLTQKPL------------FPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 614
Query: 260 GMFGNVSSDNFLHRR 274
M + N L +R
Sbjct: 615 KMTFSEHPYNNLRKR 629
>Hs16332360 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 526
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 37/255 (14%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 195 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 252
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 253 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 295
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 296 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 355
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +L K F S+I + +F G PS + WP ++ +
Sbjct: 356 GCIFGELLTQKPL------------FPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 403
Query: 260 GMFGNVSSDNFLHRR 274
M + N L +R
Sbjct: 404 KMTFSEHPYNNLRKR 418
>Hs16332358 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 782
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 37/255 (14%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 451 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 508
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 509 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 551
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 552 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 611
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +L K F S+I + +F G PS + WP ++ +
Sbjct: 612 GCIFGELLTQKPL------------FPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 659
Query: 260 GMFGNVSSDNFLHRR 274
M + N L +R
Sbjct: 660 KMTFSEHPYNNLRKR 674
>Hs10835055 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 795
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 37/255 (14%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPL----LGSETSPRYVTFKFKRYQC 79
+ +KR+ +E ++ P + E+ + + +++ + +GS Y+ + +
Sbjct: 464 VALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEH-- 521
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
DL M+ P+L P + T++I Q++ G+ ++H N I+HRD+K
Sbjct: 522 DLKSLME----TMKQPFL------------PGEVKTLMI-QLLRGVKHLHDNWILHRDLK 564
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
N++L+ + +GDFG++ +A T T Y+APELL Y +D+W++
Sbjct: 565 TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV 624
Query: 200 AVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+ +L K F S+I + +F G PS + WP ++ +
Sbjct: 625 GCIFGELLTQKPL------------FPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVK 672
Query: 260 GMFGNVSSDNFLHRR 274
M + N L +R
Sbjct: 673 KMTFSEHPYNNLRKR 687
>At3g59790 [T] KOG0660 Mitogen-activated protein kinase
Length = 393
Score = 72.4 bits (176), Expect = 8e-13
Identities = 41/137 (29%), Positives = 72/137 (51%), Gaps = 13/137 (9%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTC 171
DH + QI+ GL YIH ++HRD+KP N++L++ ++ + DFG++ ++ T
Sbjct: 161 DHGMYFMYQILRGLKYIHSANVLHRDLKPSNLLLSTQCDLKICDFGLA-RATPESNLMTE 219
Query: 172 DCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDI 231
T Y+APELL S+Y ID+W++ + ++ N + D+ + +
Sbjct: 220 YVVTRWYRAPELLLGSSDYTAAIDVWSVGCIFMEIMNREPLFPGK---------DQVNQL 270
Query: 232 KLVLTLFDKFGKPSNED 248
+L+L L G PS E+
Sbjct: 271 RLLLEL---IGTPSEEE 284
>At2g18170 [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 72.4 bits (176), Expect = 8e-13
Identities = 33/105 (31%), Positives = 60/105 (56%)
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD 165
S ++ DH + Q++ GL Y+H I+HRD+KP N+++N+ ++ + DFG++ +
Sbjct: 127 SQSLSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLARTSQGN 186
Query: 166 NEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
+ T T Y+APELL NY ID+W++ + +++ K
Sbjct: 187 EQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRK 231
>7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 317
Score = 72.4 bits (176), Expect = 8e-13
Identities = 55/231 (23%), Positives = 108/231 (45%), Gaps = 40/231 (17%)
Query: 30 RIDLELQRPPHNAHTELEILKTLS---NKHVIPLLG-----SETSPRYVTFKFKRYQCDL 81
RI L P + E+ +LK L+ + +++ L + F+ + DL
Sbjct: 58 RISLNENGVPMSTLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDL 117
Query: 82 NQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQ 141
+ +D+ K+ +P + + R+++ G+ ++H + IIHRD+KPQ
Sbjct: 118 SDLIDRLPKSGMSPPTIQR----------------LSRELLTGVDFLHSHRIIHRDLKPQ 161
Query: 142 NIMLNSYNEVVLGDFGISYNRNLDNEAK-TCDCSTSIYKAPELLFSVSNYKFEIDIWALA 200
N++++S + + DFG++ + +E K T T Y+APE+L + Y +DIW+ A
Sbjct: 162 NLLVSSQGHLKIADFGLA--KTYGSEMKLTSVVVTLWYRAPEVLLA-QPYNSTVDIWSAA 218
Query: 201 VLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQ 251
+I +++N + F S+ + +F+ G+P+ + WPQ
Sbjct: 219 CIIFEMFNRRAL------------FPGTSEKNQLDRIFELTGRPTEQQWPQ 257
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 72.0 bits (175), Expect = 1e-12
Identities = 48/176 (27%), Positives = 82/176 (46%), Gaps = 34/176 (19%)
Query: 39 PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYL- 97
P+N E+ I+K LS+ +V+ L W+ N YL
Sbjct: 71 PYNIEREIVIMKLLSHPNVLSLY-------------------------DVWETNNNLYLI 105
Query: 98 LDNSTKTYSNTIPLDHSTV-------IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNE 150
L+ + K + +DH + RQII G+ Y H GI+HRD+KP+N++L+S+
Sbjct: 106 LEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYN 165
Query: 151 VVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ + DFG++ + D + C + Y APE++ + F D+W+ V++ L
Sbjct: 166 IKIADFGMAALQT-DADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFAL 220
>Hs4506085 [T] KOG0660 Mitogen-activated protein kinase
Length = 365
Score = 72.0 bits (175), Expect = 1e-12
Identities = 51/176 (28%), Positives = 88/176 (49%), Gaps = 29/176 (16%)
Query: 42 AHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRY------QCDLNQFMDQHWKAKYNP 95
A+ EL +LK + +++VI LL T + + Y Q DL + M + +
Sbjct: 69 AYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGMEFSEEKIQ 128
Query: 96 YLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGD 155
YL + Q+++GL YIH G++HRD+KP N+ +N E+ + D
Sbjct: 129 YL--------------------VYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILD 168
Query: 156 FGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKT 211
FG++ R+ D E T T Y+APE++ S +Y +DIW++ +++++ KT
Sbjct: 169 FGLA--RHADAE-MTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKT 221
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 71.6 bits (174), Expect = 1e-12
Identities = 44/161 (27%), Positives = 77/161 (47%), Gaps = 7/161 (4%)
Query: 47 EILKTLSNKHVIPLLGSETSPRYVTFKFK-RYQCDLNQFMDQHWKAKYNPYLLDNSTKTY 105
E+ TL ++++ + SP V KF + DL D + +L +
Sbjct: 343 EVTHTLGERNILVRTSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHL------QH 396
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD 165
P + I +++ L ++H + II+RD+KP+NI+L++ + L DFG+S
Sbjct: 397 EGRFPEQRAKFYIAELVLALEHLHKHDIIYRDLKPENILLDADGHIALCDFGLSKANLSA 456
Query: 166 NEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
N C T+ Y APE+L Y ++D W+L VL+ ++
Sbjct: 457 NATTNTFCGTTEYLAPEVLLEDKGYTKQVDFWSLGVLVFEM 497
>Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 527
Score = 71.6 bits (174), Expect = 1e-12
Identities = 39/103 (37%), Positives = 57/103 (54%), Gaps = 7/103 (6%)
Query: 111 LDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISY-----NRN 163
LD ST+ I+R+++EGL Y+H NG IHRDVK NI+L V + DFG+S
Sbjct: 118 LDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDI 177
Query: 164 LDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
N+ + T + APE++ V Y F+ DIW+ + +L
Sbjct: 178 TRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIEL 220
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 71.6 bits (174), Expect = 1e-12
Identities = 42/144 (29%), Positives = 75/144 (51%), Gaps = 13/144 (9%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTC 171
+H + QI+ GL YIH ++HRD+KP N++LN+ ++ + DFG++ +++ T
Sbjct: 164 EHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLA-RVTSESDFMTE 222
Query: 172 DCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDI 231
T Y+APELL + S+Y ID+W++ + +L + K D +
Sbjct: 223 YVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGR---------DHVHQL 273
Query: 232 KLVLTLFDKFGKPSNEDWPQVTKN 255
+L++ L G PS E+ + +N
Sbjct: 274 RLLMEL---IGTPSEEELEFLNEN 294
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 71.6 bits (174), Expect = 1e-12
Identities = 33/96 (34%), Positives = 56/96 (57%), Gaps = 1/96 (1%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDN-EAKT 170
DH V + QI+ GL Y+H I+HRD+KP N+++NS + + DFG++ D + T
Sbjct: 141 DHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMT 200
Query: 171 CDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ T Y+APE+L +Y +D+W++ + +L
Sbjct: 201 QEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGEL 236
>Hs4506089 [T] KOG0660 Mitogen-activated protein kinase
Length = 557
Score = 71.2 bits (173), Expect = 2e-12
Identities = 43/185 (23%), Positives = 99/185 (53%), Gaps = 12/185 (6%)
Query: 26 IVVKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFM 85
+ VK+I L R +A E++I++ L + +++ + P+ + + ++ + +
Sbjct: 46 VAVKKIALSDARSMKHALREIKIIRRLDHDNIVKVY-EVLGPKGTDLQGELFKFSVAYIV 104
Query: 86 DQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIML 145
++ + D + T+ +H+ + + Q++ GL YIH ++HRD+KP NI +
Sbjct: 105 QEYMET-------DLARLLEQGTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFI 157
Query: 146 NSYNEVV-LGDFGIS--YNRNLDNEAKTCD-CSTSIYKAPELLFSVSNYKFEIDIWALAV 201
++ + V+ +GDFG++ +++ ++ + T Y++P LL S +NY ID+WA
Sbjct: 158 STEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGC 217
Query: 202 LISQL 206
+++++
Sbjct: 218 ILAEM 222
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 71.2 bits (173), Expect = 2e-12
Identities = 55/188 (29%), Positives = 94/188 (49%), Gaps = 27/188 (14%)
Query: 20 LELFPDIVVKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQC 79
LE D +VK+I A E+++LK L +++++ LL V K KR+
Sbjct: 36 LESDDDKMVKKI----------AMREIKLLKQLRHENLVNLLE-------VCKKKKRWYL 78
Query: 80 DLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
+ +F+D +LD+ + + N + + QII G+ + H + IIHRD+K
Sbjct: 79 -VFEFVDHT--------ILDD-LELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIK 128
Query: 140 PQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWAL 199
P+NI+++ V L DFG + E T +T Y+APELL Y +D+WA+
Sbjct: 129 PENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAI 188
Query: 200 AVLISQLW 207
L+++++
Sbjct: 189 GCLVTEMF 196
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 71.2 bits (173), Expect = 2e-12
Identities = 34/104 (32%), Positives = 61/104 (57%), Gaps = 2/104 (1%)
Query: 105 YSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNL 164
+ N +P++ ++Q++ GL YIHG GI+HRD+KP N+++NS + + + DFG+S +
Sbjct: 97 FENGMPVNQVKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLINSSDALKIADFGLSTRFIV 156
Query: 165 DNEAKTCD--CSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
D++ T+ + APEL + +DIW+ +L+ L
Sbjct: 157 DDKEILLHERIGTTPFMAPELFAKKKHRGPPVDIWSAGILVFSL 200
>SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3
Length = 381
Score = 70.9 bits (172), Expect = 2e-12
Identities = 52/189 (27%), Positives = 97/189 (50%), Gaps = 26/189 (13%)
Query: 26 IVVKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFM 85
I VKR+ LQ + + EL+I++ +S+ ++I L+ + + K + + C L ++M
Sbjct: 51 IAVKRV---LQDKRYK-NRELQIMRAISHPNIIKLIAFFHT--HNPSKDETHLCLLLEYM 104
Query: 86 ------DQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVK 139
D W + + + S K Y+ Q+ L Y+H G+ HRD+K
Sbjct: 105 PETVFDDMRWYTRRRKSIPNLSIKLYAF------------QLFRALAYLHSTGVCHRDIK 152
Query: 140 PQNIMLNSYNEVV-LGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWA 198
PQN++++ ++ L DFG S + +E + Y+APEL+F ++Y +ID+W+
Sbjct: 153 PQNLLVDYKTGILKLCDFG-SAKVLVPSEPNVSYICSRYYRAPELVFGATHYTTKIDVWS 211
Query: 199 LAVLISQLW 207
A +I++L+
Sbjct: 212 AACVIAELF 220
>HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 618
Score = 70.9 bits (172), Expect = 2e-12
Identities = 52/202 (25%), Positives = 89/202 (43%), Gaps = 24/202 (11%)
Query: 17 CADLELFPDIVVKRIDLELQRPPHNAHT-----ELEILKTLSNKHVIPLLGSETSPRYVT 71
C D++ ++ VK++ + P + E+++LK ++ ++ G P+ T
Sbjct: 372 CYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNFLHERIVQYYGCLRDPQEKT 431
Query: 72 FKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGN 131
DQ K L +N T+ Y+ RQI+EG+ Y+H N
Sbjct: 432 LSIFMEYMPGGSIKDQ---LKAYGALTENGTRKYT------------RQILEGVHYLHSN 476
Query: 132 GIIHRDVKPQNIMLNSYNEVVLGDFGISYNRN---LDNEAKTCDCSTSIYKAPELLFSVS 188
I+HRD+K NI+ +S V LGDFG S L T + +PE++ S
Sbjct: 477 MILHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVI-SGQ 535
Query: 189 NYKFEIDIWALAVLISQLWNDK 210
Y + DIW++A + ++ +K
Sbjct: 536 GYGRKADIWSVACTVVEMLTEK 557
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 70.9 bits (172), Expect = 2e-12
Identities = 54/211 (25%), Positives = 101/211 (47%), Gaps = 30/211 (14%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAK-- 169
DH + QI+ GL YIH ++HRD+KP N++LN+ ++ + DFG++ + D++
Sbjct: 124 DHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGF 183
Query: 170 -TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDEC 228
T +T Y+APE++ + Y IDIW++ +++++ +++ D+
Sbjct: 184 LTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHY------LDQL 237
Query: 229 SDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLHRRPIDEQLIQVYKWMP 288
+ I +L G PS ED + N+ + N+L P ++ W
Sbjct: 238 NHILGIL------GSPSQEDLNCII----------NLKARNYLLSLPHKNKV----PWNR 277
Query: 289 LITD-NPKLAKMWLRMVKFDGNLRISAEQLL 318
L + + K + +M+ F+ + RI EQ L
Sbjct: 278 LFPNADSKALDLLDKMLTFNPHKRIEVEQAL 308
>ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 70.9 bits (172), Expect = 2e-12
Identities = 61/239 (25%), Positives = 100/239 (41%), Gaps = 43/239 (17%)
Query: 41 NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDN 100
+A E++ LK + +K+V+ L+ + + V H +Y L+N
Sbjct: 60 SAIREIKSLKRIDSKYVVRLIDTFVYDKCV-----------------HIVLEYVETNLEN 102
Query: 101 STKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISY 160
+ I I ++ G+ H IIHRD+KP NI++ S V L DFG++
Sbjct: 103 VIRNSDKIIMPGDIKAWILMVLRGVYECHRLFIIHRDIKPNNILITSEGMVKLADFGLT- 161
Query: 161 NRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXV 220
R + N T T Y+APELL +Y +D+W++ + ++L+
Sbjct: 162 -RGIGNR-MTPQAVTRWYRAPELLMGSRDYGSPVDMWSVGCVFAELFLRVPL-------- 211
Query: 221 IDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVT-----------KNESFNGMFGNVSSD 268
F +DI+ + +F G P +WP V+ S NG+F SSD
Sbjct: 212 ----FAGDTDIQQLDMIFRALGTPVEREWPGVSTLPEFLDFQQYPKASLNGLFSAASSD 266
>CE04173 [R] KOG0667 Dual-specificity tyrosine-phosphorylation regulated
kinase
Length = 531
Score = 70.9 bits (172), Expect = 2e-12
Identities = 43/121 (35%), Positives = 67/121 (54%), Gaps = 10/121 (8%)
Query: 97 LLDNSTKTY-----SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLN--SYN 149
L D S K Y N I L++ + R+I++GLV++H + I+H D+KP+NIMLN + N
Sbjct: 273 LFDTSVKKYIKEHHPNGIALENVAAMGRKILKGLVFLHEHNIVHGDLKPENIMLNLANPN 332
Query: 150 EVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWND 209
+V LGDFG+S R C + Y+APE F Y D+W+ ++++ +
Sbjct: 333 DVKLGDFGLS--RFAKPYHDHVQCQSMFYRAPE-AFVRGRYNGATDMWSFGCTVAEMVSG 389
Query: 210 K 210
K
Sbjct: 390 K 390
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 70.9 bits (172), Expect = 2e-12
Identities = 71/297 (23%), Positives = 125/297 (41%), Gaps = 46/297 (15%)
Query: 45 ELEILKTLSNKHVIPLLGSETS----PRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDN 100
E+ +L+ +S+++V+ L+ + Y+ F + Y DL + + H + +
Sbjct: 73 EIMLLREISHENVVKLVNVHINFADMSLYLAFDYAEY--DLYEIIRHHRDK------VGH 124
Query: 101 STKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIML----NSYNEVVLGDF 156
S TY+ ++ Q++ GL Y+H N IIHRD+KP NI++ + V + DF
Sbjct: 125 SLNTYT-------VKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGDAEEHGIVKIADF 177
Query: 157 GIS--YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKT--Q 212
G++ Y L + T Y+APELL +Y +D+WA+ + ++L K Q
Sbjct: 178 GLARIYQAPLKPLSDNGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQ 237
Query: 213 XXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNG--------MFGN 264
D+ I F G P+ + WP + + + +
Sbjct: 238 GAEAKSSQNPFQLDQLDKI------FKILGHPTMDKWPTLVNLPHWQNDVQHIQAHKYDS 291
Query: 265 VSSDNFLH---RRPIDEQLIQVYKWMPL--ITDNPKLAKMWLRMVKFDGNLRISAEQ 316
V N +H + P + L ++ ++ PL IT + L + RM G A Q
Sbjct: 292 VGLHNVVHLNQKSPAYDLLSKMLEYDPLKRITASQALEHEYFRMDPLPGRNAFVASQ 348
>At3g07980 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1367
Score = 70.9 bits (172), Expect = 2e-12
Identities = 54/190 (28%), Positives = 90/190 (46%), Gaps = 18/190 (9%)
Query: 19 DLELFPDIVVKRIDLEL--QRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
DLE + +K++ LE Q + E+++LK L++K+++ LGS K K
Sbjct: 39 DLENGDFVAIKQVSLENIGQEDLNTIMQEIDLLKNLNHKNIVKYLGS--------LKTKT 90
Query: 77 YQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHR 136
+ + ++++ N L + P TV I Q++EGLVY+H G+IHR
Sbjct: 91 HLHIILEYVE-------NGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQGVIHR 143
Query: 137 DVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDI 196
D+K NI+ V L DFG++ N + T + APE++ +S DI
Sbjct: 144 DIKGANILTTKEGLVKLADFGVATKLNEADFNTHSVVGTPYWMAPEVI-ELSGVCAASDI 202
Query: 197 WALAVLISQL 206
W++ I +L
Sbjct: 203 WSVGCTIIEL 212
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 70.5 bits (171), Expect = 3e-12
Identities = 49/173 (28%), Positives = 88/173 (50%), Gaps = 19/173 (10%)
Query: 42 AHTE-----LEILKTLSNKHVIPL--LGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYN 94
AHTE L+IL+ + +++ L + SP+ K YQ + + + + + N
Sbjct: 72 AHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQ----DNKVYQHLAMECLPETLQIEIN 127
Query: 95 PYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV-L 153
Y+ T +PL H + QI G++Y+HG G+ HRD+KP N++++ V+ +
Sbjct: 128 RYV------TNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKI 181
Query: 154 GDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
DFG + + + + CS Y+APEL+ + Y +IDIW L ++ ++
Sbjct: 182 CDFGSAKKLEHNQPSISYICS-RFYRAPELIIGCTQYTTQIDIWGLGCVMGEM 233
>HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 70.5 bits (171), Expect = 3e-12
Identities = 53/191 (27%), Positives = 96/191 (49%), Gaps = 20/191 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ VK++ Q H A+ EL +LK +++K++I LL T
Sbjct: 45 DTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTP---------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 95 -QKTLEEFQDVYLVME----LMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIH 149
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ N T T Y+APE++ + YK +D
Sbjct: 150 RDLKPSNIVVKSDCTLKILDFGLA-RTACTNFMMTPYVVTRYYRAPEVILGM-GYKENVD 207
Query: 196 IWALAVLISQL 206
IW++ ++ +L
Sbjct: 208 IWSVGCIMGEL 218
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 70.5 bits (171), Expect = 3e-12
Identities = 35/100 (35%), Positives = 59/100 (59%), Gaps = 2/100 (2%)
Query: 108 TIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV-LGDFGISYNRNLDN 166
TIP+ + V + Q+ L YIH G+ HRD+KPQN++++ V+ L DFG S + +
Sbjct: 215 TIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFG-SAKQLVRG 273
Query: 167 EAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
E + Y+APEL+F ++Y ID+W+ ++++L
Sbjct: 274 EPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAEL 313
>Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 70.5 bits (171), Expect = 3e-12
Identities = 53/191 (27%), Positives = 96/191 (49%), Gaps = 20/191 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ VK++ Q H A+ EL +LK +++K++I LL T
Sbjct: 45 DTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTP---------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 95 -QKTLEEFQDVYLVME----LMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIH 149
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ N T T Y+APE++ + YK +D
Sbjct: 150 RDLKPSNIVVKSDCTLKILDFGLA-RTACTNFMMTPYVVTRYYRAPEVILGM-GYKENVD 207
Query: 196 IWALAVLISQL 206
IW++ ++ +L
Sbjct: 208 IWSVGCIMGEL 218
>Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 70.5 bits (171), Expect = 3e-12
Identities = 53/191 (27%), Positives = 96/191 (49%), Gaps = 20/191 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ VK++ Q H A+ EL +LK +++K++I LL T
Sbjct: 45 DTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTP---------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 95 -QKTLEEFQDVYLVME----LMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIH 149
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ N T T Y+APE++ + YK +D
Sbjct: 150 RDLKPSNIVVKSDCTLKILDFGLA-RTACTNFMMTPYVVTRYYRAPEVILGM-GYKENVD 207
Query: 196 IWALAVLISQL 206
IW++ ++ +L
Sbjct: 208 IWSVGCIMGEL 218
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 70.5 bits (171), Expect = 3e-12
Identities = 32/102 (31%), Positives = 63/102 (61%), Gaps = 3/102 (2%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAK-- 169
DH + QI+ GL YIH ++HRD+KP N++LN+ ++ + DFG++ + D++
Sbjct: 124 DHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGF 183
Query: 170 -TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
T +T Y+APE++ + Y IDIW++ +++++ +++
Sbjct: 184 LTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR 225
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 70.5 bits (171), Expect = 3e-12
Identities = 35/100 (35%), Positives = 59/100 (59%), Gaps = 2/100 (2%)
Query: 108 TIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV-LGDFGISYNRNLDN 166
TIP+ + V + Q+ L YIH G+ HRD+KPQN++++ V+ L DFG S + +
Sbjct: 215 TIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFG-SAKQLVRG 273
Query: 167 EAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
E + Y+APEL+F ++Y ID+W+ ++++L
Sbjct: 274 EPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAEL 313
>CE26988 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 308
Score = 70.5 bits (171), Expect = 3e-12
Identities = 64/248 (25%), Positives = 108/248 (42%), Gaps = 62/248 (25%)
Query: 19 DLELFPDIVVKRIDLELQRPPHN-----AHTELEILKTLSNKHVIPL---LGSETSPRYV 70
DLE + +K+I L + + A E+++LK + + ++I L +G TS + V
Sbjct: 24 DLESGECVAIKKIKLGSREEAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGHRTSIQLV 83
Query: 71 TFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHG 130
FMD L++ K + H I Q++ GL ++H
Sbjct: 84 F-----------DFMDTD---------LEHVIKDKEIILMPAHIKNITMQMLLGLEFLHV 123
Query: 131 NGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNY 190
+ I+HRD+KP N+++N VV T Y+APELLF +Y
Sbjct: 124 HWILHRDLKPNNLLMNKMGRVV----------------------TRWYRAPELLFGARSY 161
Query: 191 KFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWP 250
IDIW++ +I++L + + F SDI ++ +F+ G P+ E WP
Sbjct: 162 GVGIDIWSVGCIIAEL------------LLRNPIFPGESDIDQLVKIFNILGCPTPETWP 209
Query: 251 QVTKNESF 258
+T+ S+
Sbjct: 210 NMTEMNSY 217
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 70.5 bits (171), Expect = 3e-12
Identities = 36/84 (42%), Positives = 54/84 (63%), Gaps = 2/84 (2%)
Query: 120 QIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYK 179
QI++G++Y+H IIHRD+K N+ LN V +GDFG++ N D KT C T Y
Sbjct: 144 QIVDGVLYLHDLNIIHRDMKLGNLFLNDDLVVKIGDFGLATTVNGDERKKTL-CGTPNYI 202
Query: 180 APELLFSVSNYKFEIDIWALAVLI 203
APE+L + + + FE+DIWA+ ++
Sbjct: 203 APEVL-NKAGHSFEVDIWAVGCIL 225
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 70.5 bits (171), Expect = 3e-12
Identities = 33/100 (33%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 104 TYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRN 163
T +P+ S +QII G+ Y H + I+HRD+KP+N++L++ + + DFG+S N
Sbjct: 114 TRKGALPIRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLS-NYM 172
Query: 164 LDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
D + + C + Y APEL+ + E+D+W+ V++
Sbjct: 173 TDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVIL 212
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 70.5 bits (171), Expect = 3e-12
Identities = 52/190 (27%), Positives = 90/190 (47%), Gaps = 18/190 (9%)
Query: 19 DLELFPDIVVKRIDLE--LQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
DLE + +K++ LE +Q + E+++LK L++K+++ LGS K K
Sbjct: 39 DLENGDFVAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIVKYLGSS--------KTKT 90
Query: 77 YQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHR 136
+ + ++++ N L + P V I Q++EGLVY+H G+IHR
Sbjct: 91 HLHIILEYVE-------NGSLANIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQGVIHR 143
Query: 137 DVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDI 196
D+K NI+ V L DFG++ N + T + APE++ +S DI
Sbjct: 144 DIKGANILTTKEGLVKLADFGVATKLNEADVNTHSVVGTPYWMAPEVI-EMSGVCAASDI 202
Query: 197 WALAVLISQL 206
W++ + +L
Sbjct: 203 WSVGCTVIEL 212
>Hs4506785 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 70.1 bits (170), Expect = 4e-12
Identities = 51/170 (30%), Positives = 86/170 (50%), Gaps = 16/170 (9%)
Query: 42 AHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNS 101
A+ EL +LK + +++VI LL T L+ F D + + L
Sbjct: 71 AYRELRLLKHMRHENVIGLLDVFTPDE-----------TLDDFTDFYLVMPFMGTDLGKL 119
Query: 102 TKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYN 161
K + D ++ Q+++GL YIH GIIHRD+KP N+ +N E+ + DFG++
Sbjct: 120 MK--HEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLA-- 175
Query: 162 RNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKT 211
R D+E T T Y+APE++ + Y +DIW++ +++++ KT
Sbjct: 176 RQADSE-MTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKT 224
>Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 424
Score = 70.1 bits (170), Expect = 4e-12
Identities = 52/191 (27%), Positives = 97/191 (50%), Gaps = 20/191 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ VK++ Q H A+ EL +LK +++K++I LL T
Sbjct: 45 DTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTP---------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 95 -QKTLEEFQDVYLVME----LMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIH 149
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ N T T Y+APE++ + YK +D
Sbjct: 150 RDLKPSNIVVKSDCTLKILDFGLA-RTACTNFMMTPYVVTRYYRAPEVILGM-GYKENVD 207
Query: 196 IWALAVLISQL 206
IW++ +++++
Sbjct: 208 IWSVGCIMAEM 218
>Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 382
Score = 70.1 bits (170), Expect = 4e-12
Identities = 52/191 (27%), Positives = 97/191 (50%), Gaps = 20/191 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ VK++ Q H A+ EL +LK +++K++I LL T
Sbjct: 45 DTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTP---------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 95 -QKTLEEFQDVYLVME----LMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIH 149
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ N T T Y+APE++ + YK +D
Sbjct: 150 RDLKPSNIVVKSDCTLKILDFGLA-RTACTNFMMTPYVVTRYYRAPEVILGM-GYKENVD 207
Query: 196 IWALAVLISQL 206
IW++ +++++
Sbjct: 208 IWSVGCIMAEM 218
>CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 622
Score = 70.1 bits (170), Expect = 4e-12
Identities = 59/230 (25%), Positives = 96/230 (41%), Gaps = 30/230 (13%)
Query: 109 IPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIML------NSYNEVVLGDFGIS--Y 160
+P + I+ QI+ G+ Y+H N ++HRD+KP NI+L + V + D G S Y
Sbjct: 130 VPRNMVKNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIY 189
Query: 161 NRNLDNEAKTCDCSTSI-YKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXX 219
L A+ + Y+APELL +Y ID+WA+ + ++L T
Sbjct: 190 ANPLKPMAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAEL---LTAEPLFFCK 246
Query: 220 VIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSD--------NFL 271
DI V +F G PS+ DWP + K + + ++ N L
Sbjct: 247 EEDIKAQNPYHYDQVKRIFHLLGYPSDADWPDMKKMPDHQRLLSDARNEGTPIQTFPNSL 306
Query: 272 HRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLLVSI 321
HR KW I ++ ++++ D R+S E+ + I
Sbjct: 307 HR--------YFDKWK--INSQSSPYRLLVKLLTVDPTKRVSCEEAMNDI 346
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 70.1 bits (170), Expect = 4e-12
Identities = 42/104 (40%), Positives = 59/104 (56%), Gaps = 6/104 (5%)
Query: 108 TIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNE 167
T+ + I+RQI EG+ YIH I+HRD+KP+NI+L+ + V + DFG + + + E
Sbjct: 124 TLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFA-KQLQEGE 182
Query: 168 AKTCDCSTSIYKAPELL----FSVS-NYKFEIDIWALAVLISQL 206
T C T Y APE L F S Y E+DIWA V++ L
Sbjct: 183 KLTNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTL 226
>YDR283c [J] KOG1035 eIF-2alpha kinase GCN2
Length = 1659
Score = 69.7 bits (169), Expect = 5e-12
Identities = 37/104 (35%), Positives = 60/104 (57%), Gaps = 14/104 (13%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYN--RNLD--------- 165
+ RQI+E L YIH GIIHRD+KP NI ++ V +GDFG++ N R+LD
Sbjct: 815 LFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNL 874
Query: 166 ---NEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
++ T T++Y A E+L +Y +ID+++L ++ ++
Sbjct: 875 PGSSDNLTSAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEM 918
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 69.7 bits (169), Expect = 5e-12
Identities = 59/231 (25%), Positives = 106/231 (45%), Gaps = 23/231 (9%)
Query: 47 EILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYL-LDNSTKTY 105
E+ T+ + ++ + SP V +F +Q + ++ + A + L S +
Sbjct: 307 EVAHTVGERDILVQTSAADSPFIVALRFS-FQTPKDLYLVTDYMAGGELFWHLQKSVR-- 363
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS-YNRNL 164
P + + I +++ L +H GI++RD+KP+NI+L+ + L DFG+S N ++
Sbjct: 364 ---FPEERAKFYIAELLLALQALHKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSV 420
Query: 165 DNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI-------SQLWNDKTQXXXXX 217
+T C T+ Y APE++ + Y +D W+L VL+ S + D TQ
Sbjct: 421 GTTTRTF-CGTTDYLAPEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKN 479
Query: 218 XXVIDIDFD------ECSD-IKLVLTLFDKFGKPSNEDWPQVTKNESFNGM 261
+ F E D IKL+L K ++ D +V K+ F+G+
Sbjct: 480 IVFGKVRFPRGLLSVEARDLIKLLLNRNPKHRLGAHGDVEEVMKHPFFDGI 530
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 69.7 bits (169), Expect = 5e-12
Identities = 42/120 (35%), Positives = 68/120 (56%), Gaps = 6/120 (5%)
Query: 92 KYNPYLLDNSTKTYSNT---IPLDHSTVIIRQIIEGLVYIHG-NGIIHRDVKPQNIMLNS 147
+Y P L K YS+ +PL + + + QI GL YIH G+ HRD+KPQN++++
Sbjct: 116 EYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLAYIHNVAGVCHRDLKPQNLLVDP 175
Query: 148 Y-NEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
++V + DFG S + + EA + Y+APEL+F + Y IDIW+ ++++L
Sbjct: 176 LTHQVKICDFG-SAKQLVKGEANISYICSRFYRAPELIFGATEYTTSIDIWSAGCVLAEL 234
>At3g59410 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 1271
Score = 69.7 bits (169), Expect = 5e-12
Identities = 43/132 (32%), Positives = 66/132 (49%), Gaps = 16/132 (12%)
Query: 92 KYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEV 151
+Y P L ++Y N D + +IRQI+EGL +IHG GIIHRD P NI ++ N++
Sbjct: 571 EYCPRTLRQVFESY-NHFDKDFAWHLIRQIVEGLAHIHGQGIIHRDFTPNNIFFDARNDI 629
Query: 152 VLGDFGIS---YNRNLDNEA------------KTCDCSTSIYKAPELLFSVSNYKFEIDI 196
+GDFG++ LD + T T Y APE+ + D+
Sbjct: 630 KIGDFGLAKFLKLEQLDQDGGFSTDVAGSGVDSTGQAGTYFYTAPEIEQDWPKIDEKADM 689
Query: 197 WALAVLISQLWN 208
++L V+ +LW+
Sbjct: 690 YSLGVVFFELWH 701
>7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9
Length = 404
Score = 69.7 bits (169), Expect = 5e-12
Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 13/181 (7%)
Query: 31 IDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWK 90
+D E + P A E+ IL+ L +++V+ L+ + T ++ + F +
Sbjct: 84 MDNEKEGFPITALREIRILQLLKHENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLA 143
Query: 91 AKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNE 150
LL N +S L +++Q++ GL YIH N I+HRD+K N+++ +
Sbjct: 144 G-----LLSNMNVKFS----LGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGI 194
Query: 151 VVLGDFGI----SYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ L DFG+ S +N T T Y+ PELL NY +D+W +++++
Sbjct: 195 LKLADFGLARAFSIPKNESKNRYTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEM 254
Query: 207 W 207
W
Sbjct: 255 W 255
>SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 650
Score = 69.3 bits (168), Expect = 7e-12
Identities = 43/118 (36%), Positives = 68/118 (57%), Gaps = 8/118 (6%)
Query: 94 NPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNE--- 150
N Y L ++ K ++ + L+ I+RQI +GL +IH NG HRD+KP+NI+++S ++
Sbjct: 120 NLYQLISTRK--NDPLTLEQVQDIMRQIFKGLNHIHTNGFFHRDMKPENILISSNSDSSS 177
Query: 151 --VVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
V + DFG++ N T ST Y+APELL S Y F +DI+A + ++
Sbjct: 178 FNVKIADFGLAREIN-SRPPYTEYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFEI 234
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 69.3 bits (168), Expect = 7e-12
Identities = 33/98 (33%), Positives = 57/98 (57%), Gaps = 1/98 (1%)
Query: 110 PLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAK 169
P +++ + +II + ++HG+ I++RD+KP N+MLN VVL DFG+ + E
Sbjct: 123 PEEYARFYLSEIILAIEHLHGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEKT 182
Query: 170 TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLW 207
C T Y APE++ V + +D+WAL +L+ ++
Sbjct: 183 LTFCGTHEYMAPEMIRKV-GHDHAVDVWALGILMYDMF 219
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 69.3 bits (168), Expect = 7e-12
Identities = 36/113 (31%), Positives = 61/113 (53%), Gaps = 12/113 (10%)
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYN---- 161
+ T+ H QI++GL Y+H GIIHRD+KP N++LN + + DFG+S +
Sbjct: 138 NQTLNEKHFQYFFYQILKGLKYLHSAGIIHRDLKPANLLLNEDCSLKIADFGMSRSGPST 197
Query: 162 RNLDNEAKTCD--------CSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ N + ST Y+APE+L S+ Y ++DIW+ +++++
Sbjct: 198 KTTPNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEYDTQVDIWSAGCILAEM 250
>CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 375
Score = 68.9 bits (167), Expect = 9e-12
Identities = 44/169 (26%), Positives = 88/169 (52%), Gaps = 19/169 (11%)
Query: 42 AHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNS 101
A+ E +L TL + ++I LL + T L+ F + + ++ + ++
Sbjct: 73 AYREFILLTTLKHPNIIRLLNAFTP-----------DTSLSSFQEVYLVMEF----MTHN 117
Query: 102 TKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS 159
+ + LDH T+ ++ Q + + ++H G IHRD+KP NI++N + + DFG++
Sbjct: 118 LHEVIHRLRLDHETLSFLVYQSLCAIKHLHNLGFIHRDLKPSNIVVNERCVLKVLDFGLA 177
Query: 160 YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWN 208
RN+D T Y+APE++ + NY ++DIW++ +++++ N
Sbjct: 178 RRRNVDMRMSDY-VGTRYYRAPEVILGL-NYSEKVDIWSVGCILAEMIN 224
>At4g36450 [T] KOG0660 Mitogen-activated protein kinase
Length = 361
Score = 68.9 bits (167), Expect = 9e-12
Identities = 65/283 (22%), Positives = 116/283 (40%), Gaps = 57/283 (20%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFK-----FKRYQCDLNQFMDQHWKAKYNPYLLD 99
EL++L+ + +++VI L +F+ ++ DLNQ +
Sbjct: 79 ELKLLRHVRHENVISLKDVMLPTHRYSFRDVYLVYELMDSDLNQIIKS------------ 126
Query: 100 NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS 159
S ++ DH + Q++ GL Y+H I+HRD+KP N+++N+ ++ + DFG++
Sbjct: 127 ------SQSLSDDHCKYFLFQLLRGLKYLHSANILHRDLKPGNLLVNANCDLKICDFGLA 180
Query: 160 YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXX 219
+ T T Y+APELL NY ID+W++ + +++ K
Sbjct: 181 ---RTYEQFMTEYVVTRWYRAPELLLCCDNYGTSIDVWSVGCIFAEILGRKPIFPGT--- 234
Query: 220 VIDIDFDEC-SDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLHRRPIDE 278
EC + +KL++ + S +DW N + F+ P +
Sbjct: 235 -------ECLNQLKLIINVVG-----SQQDWDL--------QFIDNQKARRFIKSLPFSK 274
Query: 279 --QLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLLV 319
+Y NP + RM+ FD RIS L+
Sbjct: 275 GTHFSHIYPHA-----NPLAIDLLQRMLVFDPTKRISVSDALL 312
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 68.9 bits (167), Expect = 9e-12
Identities = 34/133 (25%), Positives = 69/133 (51%), Gaps = 13/133 (9%)
Query: 118 IRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGI-SYNRNLDNEAKTCDCSTS 176
++Q++ GL + H G++HRD+K N++L+ N + +GDFG+ ++ + + T T
Sbjct: 268 MKQLLHGLEHCHSRGVLHRDIKGSNLLLDHNNNLKIGDFGLANFYQGHQKQPLTSRVVTL 327
Query: 177 IYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLT 236
Y+ PELL ++Y +D+W+ ++++L+ K ++++ +
Sbjct: 328 WYRPPELLLGSTDYGVTVDLWSTGCILAELFTGKPIMPGR------------TEVEQLHK 375
Query: 237 LFDKFGKPSNEDW 249
+F G PS E W
Sbjct: 376 IFKLCGSPSEEYW 388
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 68.6 bits (166), Expect = 1e-11
Identities = 31/101 (30%), Positives = 59/101 (57%), Gaps = 1/101 (0%)
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD 165
+NT+ I ++ +EGL ++H NGI+HRD+K NI+L+ ++ L DFG + +
Sbjct: 474 NNTLSEGQIAAICKETLEGLQHLHENGIVHRDIKSDNILLSLQGDIKLTDFGFCAQIDSN 533
Query: 166 NEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+T T + APE++ + Y F++D+W+L ++ ++
Sbjct: 534 MTKRTTMVGTPYWMAPEVV-TRKEYGFKVDVWSLGIMAIEM 573
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 68.6 bits (166), Expect = 1e-11
Identities = 46/184 (25%), Positives = 89/184 (48%), Gaps = 20/184 (10%)
Query: 26 IVVKRIDLELQRP-PHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQF 84
+ VK +D++ P N E+ I K L++++V+ G + + F Y C +
Sbjct: 35 VAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGN-IQYLFLEY-CSGGEL 92
Query: 85 MDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIM 144
D + P + +P + Q++ G+VY+HG GI HRD+KP+N++
Sbjct: 93 FD-----RIEPDI----------GMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLL 137
Query: 145 LNSYNEVVLGDFGISYNRNLDNEAKTCD--CSTSIYKAPELLFSVSNYKFEIDIWALAVL 202
L+ + + + DFG++ +N + + C T Y APELL + +D+W+ ++
Sbjct: 138 LDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIV 197
Query: 203 ISQL 206
++ +
Sbjct: 198 LTAM 201
>Hs20986501 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 68.6 bits (166), Expect = 1e-11
Identities = 35/107 (32%), Positives = 60/107 (55%), Gaps = 8/107 (7%)
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD 165
S + L+H + Q++ GL Y+H +IHRD+KP N+++N E+ +GDFG++ R L
Sbjct: 151 SQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMA--RGLC 208
Query: 166 NEA------KTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
T +T Y+APEL+ S+ Y ID+W++ + ++
Sbjct: 209 TSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEM 255
>Hs20986499 [T] KOG0660 Mitogen-activated protein kinase
Length = 677
Score = 68.6 bits (166), Expect = 1e-11
Identities = 35/107 (32%), Positives = 60/107 (55%), Gaps = 8/107 (7%)
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD 165
S + L+H + Q++ GL Y+H +IHRD+KP N+++N E+ +GDFG++ R L
Sbjct: 12 SQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMA--RGLC 69
Query: 166 NEA------KTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
T +T Y+APEL+ S+ Y ID+W++ + ++
Sbjct: 70 TSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEM 116
>Hs20986497 [T] KOG0660 Mitogen-activated protein kinase
Length = 816
Score = 68.6 bits (166), Expect = 1e-11
Identities = 35/107 (32%), Positives = 60/107 (55%), Gaps = 8/107 (7%)
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLD 165
S + L+H + Q++ GL Y+H +IHRD+KP N+++N E+ +GDFG++ R L
Sbjct: 151 SQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMA--RGLC 208
Query: 166 NEA------KTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
T +T Y+APEL+ S+ Y ID+W++ + ++
Sbjct: 209 TSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEM 255
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 68.6 bits (166), Expect = 1e-11
Identities = 43/170 (25%), Positives = 89/170 (52%), Gaps = 19/170 (11%)
Query: 42 AHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNS 101
A+ E +L T+ + ++I LL + T L+ F + + + L+ ++
Sbjct: 82 AYREFILLTTIKHPNIIRLLNAFTP-----------DTSLSTFREVYLVME----LMTHN 126
Query: 102 TKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS 159
+ + LDH T+ + Q + + ++H +G+IHRD+KP NI++N + + DFG++
Sbjct: 127 LHEVIHRLRLDHKTLSFFVYQSLCAIKHLHNSGVIHRDLKPSNIVVNDRCVLKVLDFGLA 186
Query: 160 YNRNLDNEAKTCD-CSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWN 208
+N+D + D T Y+APE++ + Y ++DIW++ + +++ N
Sbjct: 187 RKKNVDTSMRMSDYVVTRYYRAPEVILGLP-YSEKVDIWSVGCIFAEMIN 235
>CE28674 [T] KOG0201 Serine/threonine protein kinase
Length = 651
Score = 68.6 bits (166), Expect = 1e-11
Identities = 33/105 (31%), Positives = 60/105 (56%), Gaps = 1/105 (0%)
Query: 104 TYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRN 163
T S + H VI+R+I++GL Y+H IHRD+K N++++ + +V + DFG++
Sbjct: 119 TKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLT 178
Query: 164 LDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWN 208
+ + + + APEL+ S+Y ++ DIW+L + +L N
Sbjct: 179 ETVKKRITFVGSPFWMAPELI-KQSSYDYKADIWSLGITAIELAN 222
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 68.6 bits (166), Expect = 1e-11
Identities = 33/89 (37%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
Query: 118 IRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSI 177
+RQ+ L Y H G+IHRD+KP+N++L+S + L DFG ++ D+ + C T
Sbjct: 150 VRQLANALHYCHSKGVIHRDIKPENLLLDSKLNLKLADFG--WSVVADHSKRHTLCGTMD 207
Query: 178 YKAPELLFSVSNYKFEIDIWALAVLISQL 206
Y APE++ S + F +DIWA+ +L+ ++
Sbjct: 208 YLAPEMV-SNQPHDFNVDIWAIGILLFEM 235
>CE07510 [T] KOG0201 Serine/threonine protein kinase
Length = 653
Score = 68.6 bits (166), Expect = 1e-11
Identities = 33/105 (31%), Positives = 60/105 (56%), Gaps = 1/105 (0%)
Query: 104 TYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRN 163
T S + H VI+R+I++GL Y+H IHRD+K N++++ + +V + DFG++
Sbjct: 121 TKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLT 180
Query: 164 LDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWN 208
+ + + + APEL+ S+Y ++ DIW+L + +L N
Sbjct: 181 ETVKKRITFVGSPFWMAPELI-KQSSYDYKADIWSLGITAIELAN 224
>At5g14640 [G] KOG0658 Glycogen synthase kinase-3
Length = 408
Score = 68.6 bits (166), Expect = 1e-11
Identities = 41/120 (34%), Positives = 66/120 (54%), Gaps = 6/120 (5%)
Query: 92 KYNPYLLDNSTKTYSNT---IPLDHSTVIIRQIIEGLVYIHGN-GIIHRDVKPQNIMLNS 147
+Y P + +K YS +P+ + + QI L YIHG G+ HRD+KPQN+++N
Sbjct: 150 EYVPETVYRVSKHYSRANQRMPIIYVKLYTYQICRALAYIHGGVGVCHRDIKPQNLLVNP 209
Query: 148 Y-NEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ ++V L DFG S + E + Y+APEL+F + Y IDIW+ ++++L
Sbjct: 210 HTHQVKLCDFG-SAKVLVKGEPNISYICSRYYRAPELIFGATEYTTTIDIWSAGCVLAEL 268
>At1g18350 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 307
Score = 68.6 bits (166), Expect = 1e-11
Identities = 39/96 (40%), Positives = 58/96 (59%), Gaps = 11/96 (11%)
Query: 119 RQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS--YNRNLDNEAKTCD--CS 174
RQI++GL Y+H I+HRD+KP N++LNS NEV + DFG+S R+LD C+
Sbjct: 147 RQILKGLSYLHSLKIVHRDIKPANLLLNSRNEVKIADFGVSKIITRSLD----YCNSYVG 202
Query: 175 TSIYKAPELLFSVSNYKFEI---DIWALAVLISQLW 207
T Y +PE S + ++ DIW+ V+I +L+
Sbjct: 203 TCAYMSPERFDSAAGENSDVYAGDIWSFGVMILELF 238
>At1g09840 [G] KOG0658 Glycogen synthase kinase-3
Length = 421
Score = 68.6 bits (166), Expect = 1e-11
Identities = 43/145 (29%), Positives = 76/145 (51%), Gaps = 6/145 (4%)
Query: 67 PRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNT---IPLDHSTVIIRQIIE 123
P V K + N+ + + ++ P ++ ++YS T +PL + + QI
Sbjct: 134 PNAVALKHSFFSRTDNEEVYLNLVLEFVPETVNRVARSYSRTNQLMPLIYVKLYTYQICR 193
Query: 124 GLVYIHGN-GIIHRDVKPQNIMLNSY-NEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAP 181
L YIH + G+ HRD+KPQN+++N + +++ + DFG S + E + Y+AP
Sbjct: 194 ALAYIHNSFGLCHRDIKPQNLLVNPHTHQLKICDFG-SAKVLVKGEPNVSYICSRYYRAP 252
Query: 182 ELLFSVSNYKFEIDIWALAVLISQL 206
EL+F S Y IDIW+ ++++L
Sbjct: 253 ELIFGASEYTTAIDIWSTGCVMAEL 277
>YPL042c [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 555
Score = 68.2 bits (165), Expect = 2e-11
Identities = 51/224 (22%), Positives = 96/224 (42%), Gaps = 21/224 (9%)
Query: 41 NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDN 100
+A E+ + + L NKH+ L+ + V ++ + DL Q + H
Sbjct: 203 SACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFH------------ 250
Query: 101 STKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISY 160
+ IP I+ Q+++G+ Y+H N ++HRD+KP NIM+ V +GD G++
Sbjct: 251 -SHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLA- 308
Query: 161 NRNLDNEAKTCDCSTSI-----YKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXX 215
R N +T + Y+APELL +Y +D+W++ + ++L
Sbjct: 309 -RKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIG-LQPIFK 366
Query: 216 XXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFN 259
+D + + + + G P + WP + K ++
Sbjct: 367 GEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYD 410
>Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 422
Score = 68.2 bits (165), Expect = 2e-11
Identities = 50/195 (25%), Positives = 97/195 (49%), Gaps = 20/195 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ +K++ Q H A+ EL ++K +++K++I LL T
Sbjct: 83 DAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTP---------- 132
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 133 -QKTLEEFQDVYLVME----LMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIH 187
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ + T T Y+APE++ + YK +D
Sbjct: 188 RDLKPSNIVVKSDCTLKILDFGLARTAG-TSFMMTPYVVTRYYRAPEVILGM-GYKENVD 245
Query: 196 IWALAVLISQLWNDK 210
IW++ ++ ++ K
Sbjct: 246 IWSVGCIMGEMVRHK 260
>Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 464
Score = 68.2 bits (165), Expect = 2e-11
Identities = 50/195 (25%), Positives = 97/195 (49%), Gaps = 20/195 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ +K++ Q H A+ EL ++K +++K++I LL T
Sbjct: 83 DAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTP---------- 132
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 133 -QKTLEEFQDVYLVME----LMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIH 187
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ + T T Y+APE++ + YK +D
Sbjct: 188 RDLKPSNIVVKSDCTLKILDFGLARTAG-TSFMMTPYVVTRYYRAPEVILGM-GYKENVD 245
Query: 196 IWALAVLISQLWNDK 210
IW++ ++ ++ K
Sbjct: 246 IWSVGCIMGEMVRHK 260
>Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 426
Score = 68.2 bits (165), Expect = 2e-11
Identities = 50/195 (25%), Positives = 97/195 (49%), Gaps = 20/195 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ +K++ Q H A+ EL ++K +++K++I LL T
Sbjct: 45 DAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTP---------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 95 -QKTLEEFQDVYLVME----LMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIH 149
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ + T T Y+APE++ + YK +D
Sbjct: 150 RDLKPSNIVVKSDCTLKILDFGLARTAG-TSFMMTPYVVTRYYRAPEVILGM-GYKENVD 207
Query: 196 IWALAVLISQLWNDK 210
IW++ ++ ++ K
Sbjct: 208 IWSVGCIMGEMVRHK 222
>At1g57700 [D] KOG0600 Cdc2-related protein kinase
Length = 686
Score = 68.2 bits (165), Expect = 2e-11
Identities = 36/132 (27%), Positives = 68/132 (51%), Gaps = 13/132 (9%)
Query: 119 RQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS-YNRNLDNEAKTCDCSTSI 177
+Q++ GL + H G++HRD+K N++L+ N + +GDFG+S + R + T T
Sbjct: 246 QQLLLGLEHCHSCGVLHRDIKCSNLLLDRNNNLKIGDFGLSNFYRGQRKQPLTSRVVTLW 305
Query: 178 YKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTL 237
Y+ PELL ++Y +D+W+ ++++L+ K ++++ + +
Sbjct: 306 YRPPELLLGSTDYGVTVDLWSTGCILAELFTGKPLLPGR------------TEVEQMHKI 353
Query: 238 FDKFGKPSNEDW 249
F G PS E W
Sbjct: 354 FKLCGSPSEEYW 365
>7297009 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 392
Score = 68.2 bits (165), Expect = 2e-11
Identities = 53/193 (27%), Positives = 89/193 (45%), Gaps = 22/193 (11%)
Query: 17 CADLELFPDIVVKRIDLELQRPP---HNAHTELEILKTLSNKHVIPLLGSETSPRYVTFK 73
C D E + VKR +E + P A E+ +LK L + +++ LL R +
Sbjct: 21 CRDRETGALVAVKRF-VESEDDPAIRKIALREIRLLKNLKHPNLVSLLEVFRRKRRLHLV 79
Query: 74 FKRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGI 133
F+ + + +++H + P + I Q + G+ Y H G
Sbjct: 80 FEFCELTVLHELERHPQG-----------------CPEHLTKQICYQTLLGVAYCHKQGC 122
Query: 134 IHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFE 193
+HRD+KP+NI+L + +V L DFG + + E T +T Y+APELL + Y
Sbjct: 123 LHRDIKPENILLTAQGQVKLCDFGFARMLS-PGENYTDYVATRWYRAPELLVGDTQYGTP 181
Query: 194 IDIWALAVLISQL 206
+D+WA+ L ++L
Sbjct: 182 VDVWAIGCLFAEL 194
>SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase
Length = 422
Score = 67.8 bits (164), Expect = 2e-11
Identities = 36/98 (36%), Positives = 59/98 (59%), Gaps = 4/98 (4%)
Query: 113 HSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGI----SYNRNLDNEA 168
H I QI+ GL YIH +IHRD+KP N+++N+ E+ + DFG+ S N +
Sbjct: 125 HFQSFIYQILCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGF 184
Query: 169 KTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
T +T Y+APE++ S S+Y ID+W++ ++++L
Sbjct: 185 MTEYVATRWYRAPEIMLSFSSYHKGIDVWSVGCILAEL 222
>Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 455
Score = 67.8 bits (164), Expect = 2e-11
Identities = 32/87 (36%), Positives = 51/87 (57%)
Query: 120 QIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYK 179
QI+ + Y+H N IIHRD+KP+NI+++ L DFG + + T +T Y+
Sbjct: 108 QILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYR 167
Query: 180 APELLFSVSNYKFEIDIWALAVLISQL 206
APEL+ ++Y +DIWAL +I ++
Sbjct: 168 APELVLKDTSYGKPVDIWALGCMIIEM 194
>Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 620
Score = 67.8 bits (164), Expect = 2e-11
Identities = 52/202 (25%), Positives = 89/202 (43%), Gaps = 24/202 (11%)
Query: 17 CADLELFPDIVVKRIDLELQRPPHNAHT-----ELEILKTLSNKHVIPLLGSETSPRYVT 71
C D++ ++ VK++ + P + E+++LK L ++ ++ G P+ T
Sbjct: 374 CYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKT 433
Query: 72 FKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGN 131
DQ K L +N T+ Y+ RQI+EG+ Y+H N
Sbjct: 434 LSIFMEYMPGGSIKDQ---LKAYGALTENVTRKYT------------RQILEGVHYLHSN 478
Query: 132 GIIHRDVKPQNIMLNSYNEVVLGDFGISYNRN---LDNEAKTCDCSTSIYKAPELLFSVS 188
I+ RD+K NI+ +S V LGDFG S L T + +PE++ S
Sbjct: 479 MIVLRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVI-SGE 537
Query: 189 NYKFEIDIWALAVLISQLWNDK 210
Y + DIW++A + ++ +K
Sbjct: 538 GYGRKADIWSVACTVVEMLTEK 559
>At1g57870 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 67.8 bits (164), Expect = 2e-11
Identities = 42/145 (28%), Positives = 76/145 (51%), Gaps = 6/145 (4%)
Query: 67 PRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKTYSNT---IPLDHSTVIIRQIIE 123
P V K Y N+ + + ++ P ++ + ++YS +PL + + QI
Sbjct: 133 PNVVCLKHSFYSRTENEEVYLNLVLEFVPETVNRTARSYSRMNQLMPLIYVKLYTYQICR 192
Query: 124 GLVYIHGN-GIIHRDVKPQNIMLNSY-NEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAP 181
GL Y+H G+ HRD+KPQN+++N + +++ + DFG S + E + Y+AP
Sbjct: 193 GLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFG-SAKVLVKGEPNISYICSRYYRAP 251
Query: 182 ELLFSVSNYKFEIDIWALAVLISQL 206
EL+F + Y IDIW+ ++++L
Sbjct: 252 ELIFGATEYTTAIDIWSTGCVMAEL 276
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 67.8 bits (164), Expect = 2e-11
Identities = 47/164 (28%), Positives = 72/164 (43%), Gaps = 23/164 (14%)
Query: 41 NAHTELEILKTLSNKHVIPLLGSETSPR--YVTFKFKRYQCDLNQFMDQHWKAKYNPYLL 98
N E +I L + HVI ++ S S +V +F MD H YN +
Sbjct: 47 NLRRECDIQARLKHPHVIEMIESFESKTDLFVVTEFA--------LMDLHRYLSYNGAMG 98
Query: 99 DNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGI 158
+ + + ++ L Y+H N I+HRD+KPQN++L+ L DFG+
Sbjct: 99 EEPARRVTG------------HLVSALYYLHSNRILHRDLKPQNVLLDKNMHAKLCDFGL 146
Query: 159 SYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVL 202
+ N L T T +Y APELL + Y D+W+L +
Sbjct: 147 ARNMTLGTHVLTSIKGTPLYMAPELL-AEQPYDHHADMWSLGCI 189
>YPR161c [D] KOG0600 Cdc2-related protein kinase
Length = 657
Score = 67.4 bits (163), Expect = 3e-11
Identities = 63/249 (25%), Positives = 107/249 (42%), Gaps = 40/249 (16%)
Query: 20 LELFPDIVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIPLLGS--ETSPRYVTFKFK 75
LE + +K+I + +++ P A E+ ILK L++K++I L+ + SP
Sbjct: 80 LETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASS 139
Query: 76 RYQCDLNQFMDQHWKAKYNPYLL-DNSTKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNG 132
+ PY++ D S ++ I L+ + ++ QI+EGL YIH
Sbjct: 140 NLHKSFYMIL---------PYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAK 190
Query: 133 IIHRDVKPQNIMLNSYNEVVLGDFGIS-----------YNRNLDNEAK-TCDCSTSIYKA 180
+HRD+K NI+++ + L DFG++ Y + AK T T Y+A
Sbjct: 191 FMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRA 250
Query: 181 PELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDK 240
PEL+ Y +DIW + + ++ + K +DI +F
Sbjct: 251 PELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGK------------TDIDQGHVIFKL 298
Query: 241 FGKPSNEDW 249
G P+ EDW
Sbjct: 299 LGTPTEEDW 307
>YOR231w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 508
Score = 67.4 bits (163), Expect = 3e-11
Identities = 37/94 (39%), Positives = 51/94 (53%), Gaps = 3/94 (3%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTS 176
I ++ GL Y+H +IHRD+KPQNI+LN +V L DFG+S N T TS
Sbjct: 329 IAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVS--GEAVNSLATTFTGTS 386
Query: 177 IYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
Y APE + Y D+W+L + I ++ N K
Sbjct: 387 FYMAPERI-QGQPYSVTSDVWSLGLTILEVANGK 419
>YOL128c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 67.4 bits (163), Expect = 3e-11
Identities = 48/176 (27%), Positives = 85/176 (48%), Gaps = 17/176 (9%)
Query: 37 RPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQC--DLNQFMDQHWKAKYN 94
+ P ELEIL+ + + +++ L F F+ + D +++ +Y
Sbjct: 78 KSPKVQSLELEILQNIRHPNLVTL----------EFFFESHCTTKDGGHLYQKNFVMEYI 127
Query: 95 PYLLDNSTKTY---SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEV 151
P L + Y + +P H + QI+ L+ +H I H D+KP NI++ + +
Sbjct: 128 PQTLSSEIHEYFDNGSKMPTKHIKLYTFQILRALLTLHSMSICHGDLKPSNILIIPSSGI 187
Query: 152 V-LGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ DFG + + + E KT CS Y+APELL + +Y +IDIW+L +I ++
Sbjct: 188 AKVCDFGSAQRLDDNTELKTYFCSR-FYRAPELLLNSKDYTTQIDIWSLGCIIGEM 242
>YGR040w [T] KOG0660 Mitogen-activated protein kinase
Length = 368
Score = 67.4 bits (163), Expect = 3e-11
Identities = 56/227 (24%), Positives = 104/227 (45%), Gaps = 32/227 (14%)
Query: 100 NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS 159
N+ + +T+ DH QI+ L IH +IHRD+KP N++LNS ++ + DFG++
Sbjct: 106 NNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCDLKVCDFGLA 165
Query: 160 YNRNLDNEAK-------TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQ 212
++++ T +T Y+APE++ + Y +DIW+ +++++ + K
Sbjct: 166 RCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGKPL 225
Query: 213 XXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLH 272
D + L+L + G PS ED+ Q+ + ++
Sbjct: 226 FPGR---------DYHHQLWLIL---EVLGTPSFEDFNQIKSKR----------AKEYIA 263
Query: 273 RRPIDEQLIQVYKWMPLITD-NPKLAKMWLRMVKFDGNLRISAEQLL 318
P+ L W TD NP + + +M++F+ + RISA + L
Sbjct: 264 NLPMRPPLPWETVWSK--TDLNPDMIDLLDKMLQFNPDKRISAAEAL 308
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 67.4 bits (163), Expect = 3e-11
Identities = 32/104 (30%), Positives = 62/104 (58%), Gaps = 7/104 (6%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAK-- 169
DH + QI+ GL YIH ++HRD+KP N++LN+ ++ + DFG++ R D +
Sbjct: 195 DHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLA--RVTDPQTDHT 252
Query: 170 ---TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
T +T Y+APE++ + Y ID+W++ +++++ +++
Sbjct: 253 GFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNR 296
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 67.4 bits (163), Expect = 3e-11
Identities = 32/104 (30%), Positives = 62/104 (58%), Gaps = 7/104 (6%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAK-- 169
DH + QI+ GL YIH ++HRD+KP N++LN+ ++ + DFG++ R D +
Sbjct: 127 DHVCYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLA--RVTDPQTDHT 184
Query: 170 ---TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
T +T Y+APE++ + Y ID+W++ +++++ +++
Sbjct: 185 GFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCILAEMLSNR 228
>At4g10010 [D] KOG0600 Cdc2-related protein kinase
Length = 649
Score = 67.4 bits (163), Expect = 3e-11
Identities = 45/173 (26%), Positives = 88/173 (50%), Gaps = 25/173 (14%)
Query: 118 IRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS--YNRNLDNEAKTCDCST 175
++Q++ GL + H GI+HRD+K N+++N+ + +GDFG++ Y+ D + T T
Sbjct: 261 MKQLLSGLEHCHSRGILHRDIKGPNLLVNNDGVLKIGDFGLANIYHPEQD-QPLTSRVVT 319
Query: 176 SIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVL 235
Y+APELL + Y ID+W++ ++++L+ K ++++ +
Sbjct: 320 LWYRAPELLLGATEYGPGIDLWSVGCILTELFLGKPIMPGR------------TEVEQMH 367
Query: 236 TLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFLHRRPIDEQLIQVYKWMP 288
+F G PS++ W Q TK + +F ++P L++ +K +P
Sbjct: 368 KIFKFCGSPSDDYW-QKTKLP---------LATSFKPQQPYKRVLLETFKNLP 410
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/188 (28%), Positives = 91/188 (47%), Gaps = 19/188 (10%)
Query: 33 LELQRPPHNAHTELEILKTLSNKHVIPLLGSET--SPRYVTFKFKR-YQCDLNQ-FMDQH 88
+EL + H ++ LK L +H++ E S R++ + + C L + F D+
Sbjct: 471 VELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIMLSSRSPFICRLYRTFRDE- 529
Query: 89 WKAKYNPYLLDNSTKTYSNTIPLDHSTV-------IIRQIIEGLVYIHGNGIIHRDVKPQ 141
KY LL+ T+ D + II +++ Y+H GII+RD+KP+
Sbjct: 530 ---KYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPE 586
Query: 142 NIMLNSYNEVVLGDFGISYNRNLDNEAKTCD-CSTSIYKAPELLFSVSNYKFEIDIWALA 200
N+ML+ V + DFG + + + +KT C T Y APE++ + + +D WAL
Sbjct: 587 NLMLDERGYVKIVDFG--FAKQIGTSSKTWTFCGTPEYVAPEIILN-KGHDRAVDYWALG 643
Query: 201 VLISQLWN 208
+LI +L N
Sbjct: 644 ILIHELLN 651
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 67.0 bits (162), Expect = 3e-11
Identities = 30/88 (34%), Positives = 52/88 (59%), Gaps = 1/88 (1%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTS 176
+ Q+I G+ Y+H G++HRD+K +N++L+ + +V+ DFG DNE C +
Sbjct: 155 LFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSP 214
Query: 177 IYKAPELLFSVSNYKF-EIDIWALAVLI 203
Y APEL+ S Y+ + D+W+ V++
Sbjct: 215 CYAAPELVVSTKAYEARKADVWSCGVIL 242
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 67.0 bits (162), Expect = 3e-11
Identities = 34/104 (32%), Positives = 61/104 (57%), Gaps = 4/104 (3%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV-LGDFGISYNRNLDNEAK- 169
+H+ + + Q++ GL YIH ++HRD+KP N+ +N+ + V+ +GDFG++ + K
Sbjct: 127 EHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKG 186
Query: 170 --TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKT 211
+ T Y++P LL S +NY ID+WA + +++ KT
Sbjct: 187 HLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKT 230
>Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 360
Score = 67.0 bits (162), Expect = 3e-11
Identities = 41/138 (29%), Positives = 65/138 (46%), Gaps = 12/138 (8%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTS 176
I+ Q++ GL Y+H N IIHRD+K N+++ V DFG++ + + T T
Sbjct: 143 IVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTL 202
Query: 177 IYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLT 236
Y+APELL + ID+WA+ ++++L + E I L++
Sbjct: 203 WYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGT---------SEIHQIDLIVQ 253
Query: 237 LFDKFGKPSNEDWPQVTK 254
L G PS WP +K
Sbjct: 254 L---LGTPSENIWPGFSK 268
>Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 67.0 bits (162), Expect = 3e-11
Identities = 49/191 (25%), Positives = 96/191 (49%), Gaps = 20/191 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ +K++ Q H A+ EL ++K +++K++I LL T
Sbjct: 45 DAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTP---------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 95 -QKSLEEFQDVYIVME----LMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIH 149
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ + T T Y+APE++ + YK +D
Sbjct: 150 RDLKPSNIVVKSDCTLKILDFGLARTAG-TSFMMTPYVVTRYYRAPEVILGM-GYKENVD 207
Query: 196 IWALAVLISQL 206
IW++ ++ ++
Sbjct: 208 IWSVGCIMGEM 218
>Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 67.0 bits (162), Expect = 3e-11
Identities = 49/191 (25%), Positives = 96/191 (49%), Gaps = 20/191 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ +K++ Q H A+ EL ++K +++K++I LL T
Sbjct: 45 DAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTP---------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 95 -QKSLEEFQDVYIVME----LMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIH 149
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ + T T Y+APE++ + YK +D
Sbjct: 150 RDLKPSNIVVKSDCTLKILDFGLARTAG-TSFMMTPYVVTRYYRAPEVILGM-GYKENVD 207
Query: 196 IWALAVLISQL 206
IW++ ++ ++
Sbjct: 208 IWSVGCIMGEM 218
>Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 358
Score = 67.0 bits (162), Expect = 3e-11
Identities = 69/287 (24%), Positives = 122/287 (42%), Gaps = 27/287 (9%)
Query: 41 NAHTELEILKTLSNKHVIPL--LGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLL 98
+A E+ +L+ L + +VI L + S R V F + DL + H +K N +
Sbjct: 62 SACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPM 121
Query: 99 DNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIML----NSYNEVVLG 154
+P ++ QI++G+ Y+H N ++HRD+KP NI++ V +
Sbjct: 122 Q---------LPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIA 172
Query: 155 DFGIS--YNRNLDNEAKTCDCSTSI-YKAPELLFSVSNYKFEIDIWALAVLISQLWNDKT 211
D G + +N L A + Y+APELL +Y IDIWA+ + ++L T
Sbjct: 173 DMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAEL---LT 229
Query: 212 QXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFL 271
DI + +F G P+++DW + K + + +F
Sbjct: 230 SEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTL-----QKDFR 284
Query: 272 HRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
+ LI+ Y + + K+ + +++ D RI++EQ L
Sbjct: 285 RTTYANSSLIK-YMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL 330
>Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 314
Score = 67.0 bits (162), Expect = 3e-11
Identities = 41/138 (29%), Positives = 65/138 (46%), Gaps = 12/138 (8%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTS 176
I+ Q++ GL Y+H N IIHRD+K N+++ V DFG++ + + T T
Sbjct: 114 IVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTL 173
Query: 177 IYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLT 236
Y+APELL + ID+WA+ ++++L + E I L++
Sbjct: 174 WYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGT---------SEIHQIDLIVQ 224
Query: 237 LFDKFGKPSNEDWPQVTK 254
L G PS WP +K
Sbjct: 225 L---LGTPSENIWPGFSK 239
>ECU05g1510 [TDK] KOG0668 Casein kinase II alpha subunit
Length = 319
Score = 67.0 bits (162), Expect = 3e-11
Identities = 46/165 (27%), Positives = 81/165 (48%), Gaps = 24/165 (14%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKT 104
E+ IL+ LS+K++I L+ P + + ++++ AK L
Sbjct: 77 EVLILRNLSHKNIIKLMDVVVDPESQIYSL------IFEYIEHEDYAKIFEKLCYKDIVE 130
Query: 105 YSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLN-SYNEVVLGDFGIS--YN 161
YS RQI+ L Y H GIIHRD+KPQN+++N + E+ + D+G++ Y+
Sbjct: 131 YS------------RQILSALSYCHSMGIIHRDIKPQNMVINQARRELKIIDWGLAEFYH 178
Query: 162 RNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ + ++ YK PELL Y + +DIW+ ++++L
Sbjct: 179 PKKEYSVRV---ASRYYKGPELLVDYPYYDYSLDIWSFGCVLAEL 220
>CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 353
Score = 67.0 bits (162), Expect = 3e-11
Identities = 37/90 (41%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTS 176
II Q++E L + H + IHRDVKP+NI L ++V LGDFG + N E T +T
Sbjct: 106 IIYQLLEALKFCHSHKCIHRDVKPENIFLTRNDQVKLGDFGFARIIN-TTEMYTDYVATR 164
Query: 177 IYKAPELLFSVSNYKFEIDIWALAVLISQL 206
Y++PELL Y +DIWA+ + ++L
Sbjct: 165 WYRSPELLVGDVQYGPPVDIWAVGCVYAEL 194
>At1g71530 [D] KOG0600 Cdc2-related protein kinase
Length = 655
Score = 67.0 bits (162), Expect = 3e-11
Identities = 37/137 (27%), Positives = 70/137 (51%), Gaps = 13/137 (9%)
Query: 118 IRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAK-TCDCSTS 176
++Q+ GL + H GI+HRD+K N+++N+ + +GDFG++ D + + T T
Sbjct: 252 MQQLFRGLEHCHRRGILHRDIKGSNLLINNEGVLKIGDFGLANFYRGDGDLQLTSRVVTL 311
Query: 177 IYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLT 236
Y+APELL + Y ID+W+ ++++L+ K ++++ +
Sbjct: 312 WYRAPELLLGATEYGPAIDLWSAGCILTELFAGKPIMPGR------------TEVEQMHK 359
Query: 237 LFDKFGKPSNEDWPQVT 253
+F G PS + W + T
Sbjct: 360 IFKLCGSPSEDYWRRAT 376
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 66.6 bits (161), Expect = 5e-11
Identities = 39/89 (43%), Positives = 50/89 (55%), Gaps = 2/89 (2%)
Query: 118 IRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSI 177
I QI L Y+H IIHRD+KP+NI++ N + L DFG S +N KT C T
Sbjct: 208 IYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTV-CGTID 266
Query: 178 YKAPELLFSVSNYKFEIDIWALAVLISQL 206
Y +PE++ S Y ID WAL VL +L
Sbjct: 267 YLSPEMVES-REYDHTIDAWALGVLAFEL 294
>SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 652
Score = 66.6 bits (161), Expect = 5e-11
Identities = 39/108 (36%), Positives = 57/108 (52%), Gaps = 10/108 (9%)
Query: 106 SNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISY----N 161
S + + + R ++ GL Y+H GIIHRD+KP N++LNS N V + DFG+SY
Sbjct: 236 SPVLSISEARQYFRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAG 295
Query: 162 RNLDNEAKTC-DCSTSIYKAPELLFS-----VSNYKFEIDIWALAVLI 203
N DN+ + T + APEL ++ ID+WAL V +
Sbjct: 296 LNEDNDVELAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTL 343
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 66.6 bits (161), Expect = 5e-11
Identities = 34/102 (33%), Positives = 62/102 (60%), Gaps = 9/102 (8%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIM--------LNSYNEVVLGDFGISYNRNLDNEA 168
I+ QII G+ +IH +G +HRD+KP+NI+ ++S + LGDFG++ ++ ++
Sbjct: 130 ILLQIISGIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLA-RPSVSSDP 188
Query: 169 KTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
T ST Y+APELL +Y +D++A ++ ++++ K
Sbjct: 189 LTEYVSTRWYRAPELLLRSGSYNHSVDLYAFGCIVFEIYSLK 230
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 66.6 bits (161), Expect = 5e-11
Identities = 52/171 (30%), Positives = 82/171 (47%), Gaps = 24/171 (14%)
Query: 38 PPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYL 97
P N TE+EILK L++ +I + + Y +L + + K N L
Sbjct: 266 PALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIV------LELMEGGELFDKVVGNKRL 319
Query: 98 LDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNE---VVLG 154
+ + K Y Q++ + Y+H NGIIHRD+KP+N++L+S E + +
Sbjct: 320 KEATCKLY------------FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT 367
Query: 155 DFGISYNRNLDNEAKTCDCSTSIYKAPELLFSV--SNYKFEIDIWALAVLI 203
DFG S + +T C T Y APE+L SV + Y +D W+L V++
Sbjct: 368 DFGHSKILGETSLMRTL-CGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVIL 417
>Hs5174547 [T] KOG4279 Serine/threonine protein kinase
Length = 1374
Score = 66.6 bits (161), Expect = 5e-11
Identities = 52/187 (27%), Positives = 85/187 (44%), Gaps = 16/187 (8%)
Query: 26 IVVKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFM 85
I +K I R H E+ + K L +K+++ LGS + ++ ++ +
Sbjct: 706 IAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVP---GGSL 762
Query: 86 DQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIML 145
++K+ P L DN T +QI+EGL Y+H N I+HRD+K N+++
Sbjct: 763 SALLRSKWGP-LKDNEQTIGFYT----------KQILEGLKYLHDNQIVHRDIKGDNVLI 811
Query: 146 NSYNEVV-LGDFGISYNRNLDNEAKTCDCSTSIYKAPELL-FSVSNYKFEIDIWALAVLI 203
N+Y+ V+ + DFG S N T Y APE++ Y DIW+L I
Sbjct: 812 NTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTI 871
Query: 204 SQLWNDK 210
++ K
Sbjct: 872 IEMATGK 878
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 66.6 bits (161), Expect = 5e-11
Identities = 54/183 (29%), Positives = 85/183 (45%), Gaps = 22/183 (12%)
Query: 26 IVVKRIDLELQRPPHNAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFM 85
+ +K IDLE A E+E ++ I +L SP YVT + Y D ++
Sbjct: 62 VAIKIIDLE------EAEDEIEDIQ-----QEITVLSQCDSP-YVTKYYGSYLKDTKLWI 109
Query: 86 DQHWKAKYNPYLLDNSTKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNI 143
YL S PLD + + I+R+I++GL Y+H IHRD+K N+
Sbjct: 110 IME-------YLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 162
Query: 144 MLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
+L+ + EV L DFG++ + T + APE++ S Y + DIW+L +
Sbjct: 163 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI-KQSAYDSKADIWSLGITA 221
Query: 204 SQL 206
+L
Sbjct: 222 IEL 224
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 66.6 bits (161), Expect = 5e-11
Identities = 38/130 (29%), Positives = 67/130 (51%), Gaps = 14/130 (10%)
Query: 120 QIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVV-LGDFGISYNRNLDNEAKTCDCSTSIY 178
Q++ G+ ++H + I+HRD+KP+N++++ N ++ + DFG S R NE + Y
Sbjct: 141 QLLRGIGFLHLHNIVHRDIKPKNLLVDESNGILKICDFG-SAKRLEKNEPNITYICSRYY 199
Query: 179 KAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLF 238
+APEL+F NY ID W++ ++ +L ++ F S + ++
Sbjct: 200 RAPELIFGSKNYDTSIDTWSVGTVVGELLHNSP------------IFLADSAVDILALQI 247
Query: 239 DKFGKPSNED 248
FG PS ED
Sbjct: 248 KAFGTPSKED 257
>At1g33770 [D] KOG0600 Cdc2-related protein kinase
Length = 614
Score = 66.6 bits (161), Expect = 5e-11
Identities = 40/142 (28%), Positives = 74/142 (51%), Gaps = 18/142 (12%)
Query: 118 IRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGI-SYNRNLDNEAKTCDCSTS 176
++Q++ GL + H GI+HRD+K N+++N+ + +GDFG+ S+ + ++ T T
Sbjct: 246 MKQLLCGLEHCHSRGILHRDIKGSNLLVNNDGVLKIGDFGLASFYKPDQDQPLTSRVVTL 305
Query: 177 IYKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLT 236
Y+APELL + Y ID+W++ ++++L+ V ++++ +
Sbjct: 306 WYRAPELLLGSTEYGPAIDLWSVGCILAELF------------VCKPIMPGRTEVEQMHK 353
Query: 237 LFDKFGKPSNEDW-----PQVT 253
+F G PS E W PQ T
Sbjct: 354 IFKLCGSPSEEFWNTTKFPQAT 375
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 66.6 bits (161), Expect = 5e-11
Identities = 70/287 (24%), Positives = 121/287 (41%), Gaps = 27/287 (9%)
Query: 41 NAHTELEILKTLSNKHVIPLLGSETS--PRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLL 98
+A E+ +L+ L +++VI L+ S R V + DL + H AK
Sbjct: 139 SACREIALLRELKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAK------ 192
Query: 99 DNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIML----NSYNEVVLG 154
+TK +P ++ QI++G+ Y+H N ++HRD+KP NI++ N V +
Sbjct: 193 --ATKKQV-VVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIA 249
Query: 155 DFGIS--YNRNLDNEAKTCDCSTSI-YKAPELLFSVSNYKFEIDIWALAVLISQLWNDKT 211
D G + +N L A + Y+APELL +Y IDIWA+ + ++L T
Sbjct: 250 DMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAEL---LT 306
Query: 212 QXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGMFGNVSSDNFL 271
DI + +F+ G P ++DW + K + + +
Sbjct: 307 SEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKD------F 360
Query: 272 HRRPIDEQLIQVYKWMPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
R + Y I + K + +++ D N RI++EQ +
Sbjct: 361 KRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAM 407
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 66.2 bits (160), Expect = 6e-11
Identities = 44/162 (27%), Positives = 74/162 (45%), Gaps = 18/162 (11%)
Query: 43 HTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNST 102
+ E+ LK LS+ +++ L + RY+ + Y C ++ Y+
Sbjct: 98 YREINALKHLSHPNIVKLEEVLQNSRYIGIVLE-YACG----------GEFYKYIQKKRR 146
Query: 103 KTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNR 162
N L Q+I G+ YIH G++HRD+K +N++L+ +V+ DFG
Sbjct: 147 LKEMNACRL------FSQLISGVHYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEF 200
Query: 163 NLDNEAKTCDCSTSIYKAPELLFSVSNYKF-EIDIWALAVLI 203
NE C + Y APEL+ S Y+ + DIW+ V++
Sbjct: 201 CSRNELMKTSCGSPCYAAPELVISAEPYEARKADIWSCGVIL 242
>SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase
Length = 532
Score = 66.2 bits (160), Expect = 6e-11
Identities = 46/159 (28%), Positives = 74/159 (45%), Gaps = 19/159 (11%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKT 104
E+ IL+ L + ++I L P+Y + DL+ + +H + LD T
Sbjct: 71 EVTILRQLHHPNIITLYQVFRVPKYTVLALEYMDTDLHSMVVKHNR-------LDECT-- 121
Query: 105 YSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNL 164
+ I RQI+ + Y H + + HRD+K +NI+LN V L DFG+S N L
Sbjct: 122 ---------TRKIFRQIVHAIDYCHLHRVAHRDLKLENILLNKDLVVKLTDFGLS-NFML 171
Query: 165 DNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
D + C T Y APE++ ++D+W +L+
Sbjct: 172 DGSFLSTSCGTPHYAAPEVIQGRYYDGCDVDVWGCGILL 210
>Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 384
Score = 66.2 bits (160), Expect = 6e-11
Identities = 48/191 (25%), Positives = 96/191 (50%), Gaps = 20/191 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ +K++ Q H A+ EL ++K +++K++I LL T
Sbjct: 45 DAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTP---------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 95 -QKSLEEFQDVYIVME----LMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIH 149
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ + T T Y+APE++ + YK +D
Sbjct: 150 RDLKPSNIVVKSDCTLKILDFGLARTAG-TSFMMTPYVVTRYYRAPEVILGM-GYKENVD 207
Query: 196 IWALAVLISQL 206
+W++ ++ ++
Sbjct: 208 LWSVGCIMGEM 218
>Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 427
Score = 66.2 bits (160), Expect = 6e-11
Identities = 48/191 (25%), Positives = 96/191 (50%), Gaps = 20/191 (10%)
Query: 19 DLELFPDIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKR 76
D L ++ +K++ Q H A+ EL ++K +++K++I LL T
Sbjct: 45 DAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTP---------- 94
Query: 77 YQCDLNQFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIH 135
Q L +F D + + L+D N + + + + ++ Q++ G+ ++H GIIH
Sbjct: 95 -QKSLEEFQDVYIVME----LMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIH 149
Query: 136 RDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEID 195
RD+KP NI++ S + + DFG++ + T T Y+APE++ + YK +D
Sbjct: 150 RDLKPSNIVVKSDCTLKILDFGLARTAG-TSFMMTPYVVTRYYRAPEVILGM-GYKENVD 207
Query: 196 IWALAVLISQL 206
+W++ ++ ++
Sbjct: 208 LWSVGCIMGEM 218
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 66.2 bits (160), Expect = 6e-11
Identities = 42/166 (25%), Positives = 77/166 (46%), Gaps = 19/166 (11%)
Query: 41 NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDN 100
N E+EI++ L + +++ +L S + + V + +L Q ++ K
Sbjct: 47 NLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGK---------- 96
Query: 101 STKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISY 160
+P D I Q++ L Y+H + I+HRD+KPQNI+L + L DFG +
Sbjct: 97 --------LPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFAR 148
Query: 161 NRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ + T T +Y +PEL+ Y D+W++ ++ +L
Sbjct: 149 AMSTNTMVLTSIKGTPLYMSPELV-EERPYDHTADLWSVGCILYEL 193
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 66.2 bits (160), Expect = 6e-11
Identities = 35/95 (36%), Positives = 56/95 (58%), Gaps = 2/95 (2%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTC 171
D + + +QII G+ Y H N I+HRD+KP+N++L+S + + DFG+S N D
Sbjct: 117 DEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLS-NVMHDGHFLKT 175
Query: 172 DCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
C + Y APE++ S Y ++DIW+ V++ L
Sbjct: 176 SCGSPNYAAPEVI-SGKPYGPDVDIWSCGVILYAL 209
>At1g54610 [D] KOG0600 Cdc2-related protein kinase
Length = 572
Score = 66.2 bits (160), Expect = 6e-11
Identities = 47/169 (27%), Positives = 82/169 (47%), Gaps = 28/169 (16%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLN---QFMDQHWKAKYNPYLLDNS 101
E+ +L+ L + +V+ L G TS R C L Q+MD D +
Sbjct: 165 EILVLRRLDHPNVVKLEGLVTS---------RMSCSLYLVFQYMDH-----------DLA 204
Query: 102 TKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS 159
S + S V ++RQ+I GL + H G++HRD+K N++++ + + DFG++
Sbjct: 205 GLASSPVVKFSESEVKCLMRQLISGLEHCHSRGVLHRDIKGSNLLIDDGGVLKIADFGLA 264
Query: 160 --YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
++ N T T Y+APELL ++Y ID+W+ ++++L
Sbjct: 265 TIFDPN-HKRPMTSRVVTLWYRAPELLLGATDYGVGIDLWSAGCILAEL 312
>7297631 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 372
Score = 66.2 bits (160), Expect = 6e-11
Identities = 45/185 (24%), Positives = 94/185 (50%), Gaps = 20/185 (10%)
Query: 25 DIVVKRIDLELQRPPH--NAHTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLN 82
++ +K++ Q H A+ E +++K +++K++I LL + T R +L
Sbjct: 49 NVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQR-----------NLE 97
Query: 83 QFMDQHWKAKYNPYLLD-NSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQ 141
+F D + + L+D N + + D + ++ Q++ G+ ++H GIIHRD+KP
Sbjct: 98 EFQDVYLVME----LMDANLCQVIQMDLDHDRMSYLLYQMLCGIKHLHSAGIIHRDLKPS 153
Query: 142 NIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAV 201
NI++ + + + DFG++ T T Y+APE++ + Y +DIW++
Sbjct: 154 NIVVKADCTLKILDFGLARTAG-TTFMMTPYVVTRYYRAPEVILGM-GYTENVDIWSVGC 211
Query: 202 LISQL 206
++ ++
Sbjct: 212 IMGEM 216
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 66.2 bits (160), Expect = 6e-11
Identities = 34/88 (38%), Positives = 52/88 (58%), Gaps = 1/88 (1%)
Query: 119 RQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIY 178
+QII G+ Y H + I+HRD+KP+N++L+ V + DFG+S N LD E C + Y
Sbjct: 133 QQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLS-NMMLDGEFLRTSCGSPNY 191
Query: 179 KAPELLFSVSNYKFEIDIWALAVLISQL 206
APE++ E+DIW+ V++ L
Sbjct: 192 AAPEVISGKLYAGPEVDIWSCGVILYAL 219
>SPAC1D4.13 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K)
Length = 340
Score = 65.9 bits (159), Expect = 8e-11
Identities = 39/99 (39%), Positives = 57/99 (57%), Gaps = 4/99 (4%)
Query: 109 IPLDHSTVIIRQIIEGLVYIHGN-GIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNE 167
IPLD II +++GL+Y++ IIHRD+KP N+++NS E+ L DFG+S L N
Sbjct: 157 IPLDILGKIINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVS--GELVNS 214
Query: 168 AKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
TS Y +PE + Y + DIW+L + I +L
Sbjct: 215 VAQTFVGTSTYMSPERIRG-GKYTVKSDIWSLGISIIEL 252
>Hs14589902 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 278
Score = 65.9 bits (159), Expect = 8e-11
Identities = 38/103 (36%), Positives = 58/103 (55%), Gaps = 5/103 (4%)
Query: 108 TIPLDHSTVIIRQIIEGLVYIHGN-GIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDN 166
TIP D I I++ L ++H +IHRDVKP N+++N+ +V + DFGIS +D+
Sbjct: 93 TIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGIS-GYLVDS 151
Query: 167 EAKTCDCSTSIYKAPELL---FSVSNYKFEIDIWALAVLISQL 206
AKT D Y APE + + Y + DIW+L + + +L
Sbjct: 152 VAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIEL 194
>Hs14589900 [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase
MKK3/MKK6
Length = 334
Score = 65.9 bits (159), Expect = 8e-11
Identities = 38/103 (36%), Positives = 58/103 (55%), Gaps = 5/103 (4%)
Query: 108 TIPLDHSTVIIRQIIEGLVYIHGN-GIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDN 166
TIP D I I++ L ++H +IHRDVKP N+++N+ +V + DFGIS +D+
Sbjct: 149 TIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGIS-GYLVDS 207
Query: 167 EAKTCDCSTSIYKAPELL---FSVSNYKFEIDIWALAVLISQL 206
AKT D Y APE + + Y + DIW+L + + +L
Sbjct: 208 VAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIEL 250
>ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3
Length = 334
Score = 65.9 bits (159), Expect = 8e-11
Identities = 34/89 (38%), Positives = 51/89 (57%), Gaps = 1/89 (1%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTS 176
+ RQI+EGL Y+H I HRD+KP NI++++ V + D G + T CS
Sbjct: 155 VYRQILEGLRYLHEKNICHRDMKPSNILIDTNGLVKICDLGSAKVIKSGERNITYICS-R 213
Query: 177 IYKAPELLFSVSNYKFEIDIWALAVLISQ 205
Y+APE L Y F+IDIW++ +I++
Sbjct: 214 FYRAPENLLDYKEYDFKIDIWSVGCVIAE 242
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 65.9 bits (159), Expect = 8e-11
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 108 TIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISY------- 160
T+ H Q++ GL Y+H GIIHRD+KP N++LN + + DFG++
Sbjct: 153 TLMEQHFQYFFYQLLRGLKYLHSAGIIHRDLKPSNLLLNGDCLLRIADFGMARAYASAST 212
Query: 161 ---NRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
+ N+ T ST Y+APE+LFS+ Y ++D+W+ + +++
Sbjct: 213 VRDDANVGGH-MTQYVSTRWYRAPEILFSMVEYDTKVDLWSAGCIFAEM 260
>At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 561
Score = 65.9 bits (159), Expect = 8e-11
Identities = 31/93 (33%), Positives = 54/93 (57%), Gaps = 3/93 (3%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGIS---YNRNLDNEAKTCDC 173
++R+ ++ LVY+H +G IHRDVK NI+L+S V L DFG+S ++ ++
Sbjct: 119 LLRETLKALVYLHAHGHIHRDVKAGNILLDSNGAVKLADFGVSACMFDTGDRQRSRNTFV 178
Query: 174 STSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
T + APE++ + Y F+ D+W+ + +L
Sbjct: 179 GTPCWMAPEVMQQLHGYDFKADVWSFGITALEL 211
>At4g22940 [D] KOG0600 Cdc2-related protein kinase
Length = 458
Score = 65.9 bits (159), Expect = 8e-11
Identities = 45/173 (26%), Positives = 83/173 (47%), Gaps = 27/173 (15%)
Query: 45 ELEILKTLSNKHVIPLLG-----SETSPRYVTFKFKRYQC-DLNQFMDQHWKAKYNPYLL 98
E+ IL+ L + +VI L G ++S Y+ F++ + L+ + H+
Sbjct: 150 EIIILRKLDHPNVIKLEGLMLVDHDSSTLYLIFEYMEHDLLGLSSLLGVHFS-------- 201
Query: 99 DNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGI 158
+ K Y +RQ++ GL + H N ++HRD+K N+++N + + DFG+
Sbjct: 202 EPQVKCY------------MRQLLRGLDHCHTNHVLHRDMKSSNLLINGDGVLKIADFGL 249
Query: 159 SYNRNLDNEAK-TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
+ + N T +T Y+ PELL S+Y +D+W+ +I +L+ K
Sbjct: 250 ATFFDPHNSVPLTTHVATLWYRPPELLLGASHYGIGVDLWSTGCVIGELYAGK 302
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 65.9 bits (159), Expect = 8e-11
Identities = 49/168 (29%), Positives = 90/168 (53%), Gaps = 18/168 (10%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNSTKT 104
EL+I++ L + +V+ L S S T K + Y LN ++ Y P + ++++
Sbjct: 143 ELQIMRMLDHPNVVELKHSFFS---TTEKDELY---LNLVLE------YVPETIYRASRS 190
Query: 105 YSNT---IPLDHSTVIIRQIIEGLVYIHGN-GIIHRDVKPQNIMLNSY-NEVVLGDFGIS 159
Y+ +PL + + QI + Y+H G+ HRD+KPQN+++N+ +EV + DFG S
Sbjct: 191 YTKMNQHMPLIYIQLYTYQICRAMNYLHQVVGVCHRDIKPQNLLVNNVTHEVKICDFG-S 249
Query: 160 YNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLW 207
+ E + Y+APEL+F + Y ID+W++ ++++L+
Sbjct: 250 AKMLIPGEPNISYICSRYYRAPELIFGATEYTSAIDMWSVGCVMAELF 297
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 65.9 bits (159), Expect = 8e-11
Identities = 41/120 (34%), Positives = 66/120 (54%), Gaps = 6/120 (5%)
Query: 92 KYNPYLLDNSTKTYSNT---IPLDHSTVIIRQIIEGLVYIH-GNGIIHRDVKPQNIMLNS 147
+Y P L K Y+++ +P+ + + QI GL YIH G+ HRDVKPQN++++
Sbjct: 148 EYVPETLYRVLKHYTSSNQRMPIFYVKLYTYQIFRGLAYIHTAPGVCHRDVKPQNLLVDP 207
Query: 148 Y-NEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
++ L DFG S + EA + Y+APEL+F + Y IDIW+ ++++L
Sbjct: 208 LTHQCKLCDFG-SAKVLVKGEANISYICSRYYRAPELIFGATEYTSSIDIWSAGCVLAEL 266
>YKL161c [T] KOG0660 Mitogen-activated protein kinase
Length = 433
Score = 65.5 bits (158), Expect = 1e-10
Identities = 54/212 (25%), Positives = 95/212 (44%), Gaps = 33/212 (15%)
Query: 113 HSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGI--SYNRNLD-NEAK 169
H I QI+ L YIH ++H D+KP+N+++NS ++ + +FG+ SY+ N N+
Sbjct: 129 HFQSFIYQILCALKYIHSANVLHCDLKPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGF 188
Query: 170 TCDCSTSI-YKAPELLFSVSNYKFEIDIWALAVLISQLWNDKTQXXXXXXXVIDIDFDEC 228
TSI YKAPE+L + +DIW+ ++++L K F+
Sbjct: 189 IKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAELLGRKPM------------FEGK 236
Query: 229 SDIKLVLTLFDKFGKPSNEDWPQVTKNESFNGM--FGNVSSDNFLHRRPIDEQLIQVYKW 286
+ + + G P E ++ + +N + FGN+ +F P
Sbjct: 237 DYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESILP----------- 285
Query: 287 MPLITDNPKLAKMWLRMVKFDGNLRISAEQLL 318
NP+ ++ +M++FD RI+ E L
Sbjct: 286 ----GANPEALELLKKMLEFDPKKRITVEDAL 313
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 65.5 bits (158), Expect = 1e-10
Identities = 33/100 (33%), Positives = 56/100 (56%), Gaps = 5/100 (5%)
Query: 109 IPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEA 168
+P + RQII G+ Y H GI+HRD+KP+N++L+ + + DFG++ L+ E
Sbjct: 128 LPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMA---ALETEG 184
Query: 169 KTCD--CSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
K + C + Y APE++ + F D+W+ V++ L
Sbjct: 185 KLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFAL 224
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 65.5 bits (158), Expect = 1e-10
Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 25/189 (13%)
Query: 25 DIVVKRIDLE-LQRPPHNAHTELEILKTLS-NKHVIPLLGSETSPRYVTFKFKRYQCDLN 82
++ +R+ E L+ E IL+ ++ + H+I L+ S S ++ F
Sbjct: 56 EVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVF-------- 107
Query: 83 QFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQN 142
D K + YL + + T I+R ++E + ++H N I+HRD+KP+N
Sbjct: 108 ---DLMRKGELFDYLTEKVALSEKET------RSIMRSLLEAVSFLHANNIVHRDLKPEN 158
Query: 143 IMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELL-----FSVSNYKFEIDIW 197
I+L+ ++ L DFG S + + + C T Y APE+L + Y E+D+W
Sbjct: 159 ILLDDNMQIRLSDFGFSCHLEPGEKLREL-CGTPGYLAPEILKCSMDETHPGYGKEVDLW 217
Query: 198 ALAVLISQL 206
A V++ L
Sbjct: 218 ACGVILFTL 226
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 65.5 bits (158), Expect = 1e-10
Identities = 31/88 (35%), Positives = 52/88 (58%), Gaps = 1/88 (1%)
Query: 119 RQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIY 178
+QII G+ Y H + ++HRD+KP+N++L+ N V + DFG+S N D + C + Y
Sbjct: 130 QQIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLS-NIMTDGDFLRTSCGSPNY 188
Query: 179 KAPELLFSVSNYKFEIDIWALAVLISQL 206
APE++ E+D+W+ V++ L
Sbjct: 189 AAPEVISGKLYAGPEVDVWSCGVILYAL 216
>CE20636 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 687
Score = 65.5 bits (158), Expect = 1e-10
Identities = 37/109 (33%), Positives = 53/109 (47%), Gaps = 4/109 (3%)
Query: 97 LLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDF 156
L D + Y T H +Q+I GL YIH G+ HRD+KP+N+ML + + DF
Sbjct: 420 LFDKISSEYRLTSSQAHG--YFKQLIAGLRYIHSKGVTHRDIKPENLMLTKAGVLKITDF 477
Query: 157 GISYNRNLDNEAKTCD--CSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
G+ + E D C T Y APE+L +DIW+ V++
Sbjct: 478 GLGTLHIIKGEESLMDTRCGTPQYAAPEVLVGNQYRGPPVDIWSAGVVL 526
Score = 49.3 bits (116), Expect = 7e-06
Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 8/100 (8%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIML-NSYNEVV-----LGDFGISYNRNLD 165
+++ +Q+I GL +IH + I+HRD+K +N++L S + +V + DFG++ +D
Sbjct: 123 ENAQCFFKQLISGLKFIHEHEIVHRDIKLENLLLMKSKSNLVPDTLKIADFGLATEYMVD 182
Query: 166 NEAKTC--DCSTSIYKAPELLFSVSNYKFEIDIWALAVLI 203
E +C + Y APE+ + D+W+ V++
Sbjct: 183 GEELMLVDNCGSPPYAAPEVYSKQGHRGPPTDVWSSGVIL 222
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 65.5 bits (158), Expect = 1e-10
Identities = 31/88 (35%), Positives = 52/88 (58%), Gaps = 1/88 (1%)
Query: 119 RQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIY 178
+QII G+ Y H + ++HRD+KP+N++L+ N V + DFG+S N D + C + Y
Sbjct: 130 QQIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLS-NIMTDGDFLRTSCGSPNY 188
Query: 179 KAPELLFSVSNYKFEIDIWALAVLISQL 206
APE++ E+D+W+ V++ L
Sbjct: 189 AAPEVISGKLYAGPEVDVWSCGVILYAL 216
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 65.5 bits (158), Expect = 1e-10
Identities = 53/263 (20%), Positives = 115/263 (43%), Gaps = 35/263 (13%)
Query: 26 IVVKRIDLELQRP--PHNAHTELEILKTLSNKHVIP-----LLGSETSPRYVTFKFKRYQ 78
+ +KR+ +E ++ P A E+ +L N I LLGS Y+ +F +
Sbjct: 382 VALKRLKMEKEKEGFPITALREINMLLKAGNHPNIVNVKEILLGSNMDKIYMAMEFVEH- 440
Query: 79 CDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDV 138
D+ +D + K +S + +++Q++ G+ ++H I+HRD+
Sbjct: 441 -DMKSLLDT----------MSRRNKRFS----IGEQKTLLQQLLSGIEHMHKLWILHRDL 485
Query: 139 KPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWA 198
K N++++ + + DFG++ + T T Y++PELL Y +D+W+
Sbjct: 486 KTSNLLMSHKGILKIADFGLAREYGDPLKKFTSIVVTLWYRSPELLLGTRLYSTPVDMWS 545
Query: 199 LAVLISQLWNDKTQXXXXXXXVIDIDFDECSDIKLVLTLFDKFGKPSNEDWPQVTKNESF 258
+ ++++ ++ F +++ + +F + G P+ WP VT+ + +
Sbjct: 546 VGCIMAEF------------ILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTELDGW 593
Query: 259 NGMFGNVSSDNFLHRRPIDEQLI 281
+ N L +R + +L+
Sbjct: 594 KALTFEKYPYNQLRKRFLAGRLL 616
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 65.5 bits (158), Expect = 1e-10
Identities = 33/95 (34%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTC 171
D + +QII G+ Y H N ++HRD+KP+N++L+S V + DFG+S N D
Sbjct: 117 DEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLS-NIMRDGHFLKT 175
Query: 172 DCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
C + Y APE++ E+D+W+ V++ L
Sbjct: 176 SCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYAL 210
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 65.5 bits (158), Expect = 1e-10
Identities = 55/190 (28%), Positives = 88/190 (45%), Gaps = 33/190 (17%)
Query: 27 VVKRIDLELQRP------PHNAHTELEILKTLSNKHVIPLLGSETSPR--YVTFKFKRYQ 78
+VK+ L RP P E +I+K LS+ V+ + P Y+ +F R
Sbjct: 187 IVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGG 246
Query: 79 CDLNQFMDQHWKAKYNPYLLDNSTKTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDV 138
LN+ + N L ++ +K Y Q+ + Y+H GI HRD+
Sbjct: 247 DLLNRIIS-------NKLLSEDISKLY------------FYQMCHAVKYLHDRGITHRDL 287
Query: 139 KPQNIMLNSYNEVVL---GDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSN--YKFE 193
KP N++L + +E L DFG+S D+ +T C T +Y APE+L + Y +
Sbjct: 288 KPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTL-CGTPLYVAPEVLITGGREAYTKK 346
Query: 194 IDIWALAVLI 203
+DIW+L V++
Sbjct: 347 VDIWSLGVVL 356
>SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase
Length = 652
Score = 65.1 bits (157), Expect = 1e-10
Identities = 33/108 (30%), Positives = 55/108 (50%), Gaps = 2/108 (1%)
Query: 96 YLLDNSTKTYSNTIPLDHSTV--IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVL 153
Y S +T P+ + I+R+ ++ L +IH GIIHRD+K NI+++ V L
Sbjct: 90 YCHGGSVRTLMEAGPISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVSMSGNVKL 149
Query: 154 GDFGISYNRNLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAV 201
DFG++ N++ + T + APE++ Y DIW+L +
Sbjct: 150 CDFGVAAELNINRRKRITFIGTPYWMAPEVIRDGQEYNVMADIWSLGI 197
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 65.1 bits (157), Expect = 1e-10
Identities = 48/173 (27%), Positives = 87/173 (49%), Gaps = 30/173 (17%)
Query: 45 ELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQC-DLNQFMDQHWKAKYNPYLLDNSTK 103
E+ ILK++ ++H+I L +P+ + + + +L + +D+ + +N T+
Sbjct: 163 EVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDR------KGHFSENETR 216
Query: 104 TYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNS-----YNEVVLG---- 154
II+ + + Y+H N I+HRD+K +NIM+ S NE+ L
Sbjct: 217 W------------IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVT 264
Query: 155 DFGISYNRNLDNEAK-TCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
DFG++ + +EA C T IY APE++ S +Y + DIW++ V++ L
Sbjct: 265 DFGLAVKKQSRSEAMLQATCGTPIYMAPEVI-SAHDYSQQCDIWSIGVVMYML 316
>ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 516
Score = 65.1 bits (157), Expect = 1e-10
Identities = 49/168 (29%), Positives = 83/168 (49%), Gaps = 24/168 (14%)
Query: 43 HTELEILKTLSNKHVIPLLGSETSPRYVTFKFKRYQCDLNQFMDQHWKAKYNPYLLDNST 102
+ E+E+L T+ +++++ ++G F+ K++ + + D + + N Y +D
Sbjct: 45 YREIEMLSTIKHENIVGIVGR--------FESKKHVYMVEELCDFNLVSFLNEYEVDE-- 94
Query: 103 KTYSNTIPLDHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNR 162
D + I+R I+ GL +IH GIIHRD+K NI+L N V + DFG+S
Sbjct: 95 ---------DVALKILRMILCGLRHIHSLGIIHRDLKLGNILLKG-NTVKICDFGLSCYV 144
Query: 163 NLDNEAKTCDCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQLWNDK 210
+N C T Y APE++ Y F +D+W+ V+ L K
Sbjct: 145 EENNSE---FCGTMDYLAPEVV-DGKKYSFGVDMWSAGVVFYVLLTKK 188
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 65.1 bits (157), Expect = 1e-10
Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 3/89 (3%)
Query: 119 RQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIY 178
RQI+ + Y+H IIHRD+K +N++L+ + + DFG S +L N+ T C + Y
Sbjct: 226 RQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTF-CGSPPY 284
Query: 179 KAPELLFSVSNYKF-EIDIWALAVLISQL 206
APE LFS Y E+D+W+L V++ L
Sbjct: 285 AAPE-LFSGKKYDGPEVDVWSLGVILYTL 312
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 65.1 bits (157), Expect = 1e-10
Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 3/89 (3%)
Query: 119 RQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTCDCSTSIY 178
RQI+ + Y+H IIHRD+K +N++L+ + + DFG S +L N+ T C + Y
Sbjct: 274 RQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTF-CGSPPY 332
Query: 179 KAPELLFSVSNYKF-EIDIWALAVLISQL 206
APE LFS Y E+D+W+L V++ L
Sbjct: 333 AAPE-LFSGKKYDGPEVDVWSLGVILYTL 360
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 65.1 bits (157), Expect = 1e-10
Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 1/95 (1%)
Query: 112 DHSTVIIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAKTC 171
D + +QII G+ Y H N ++HRD+KP+N++L+S + + DFG+S N D
Sbjct: 118 DEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLS-NVMRDGHFLKT 176
Query: 172 DCSTSIYKAPELLFSVSNYKFEIDIWALAVLISQL 206
C + Y APE++ E+D+W+ V++ L
Sbjct: 177 SCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYAL 211
>7302048 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 1589
Score = 65.1 bits (157), Expect = 1e-10
Identities = 36/110 (32%), Positives = 61/110 (54%), Gaps = 20/110 (18%)
Query: 117 IIRQIIEGLVYIHGNGIIHRDVKPQNIMLNSYNEVVLGDFGISYNRNLDNEAK------- 169
+ R+I EGL +IH GIIHRD+KP NI L+S++++ +GDFG++ L +A
Sbjct: 724 LFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHDQIKIGDFGLATTSFLALQAHDAAPAPV 783
Query: 170 -----------TCDCSTSIYKAPELLFSVSN--YKFEIDIWALAVLISQL 206
T T++Y APEL + S Y ++D++ L +++ ++
Sbjct: 784 NQITSAEDGTGTGKVGTTLYVAPELTGNASKSVYNQKVDMYTLGIILFEM 833
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.138 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,769,197
Number of Sequences: 60738
Number of extensions: 866139
Number of successful extensions: 4601
Number of sequences better than 1.0e-05: 962
Number of HSP's better than 0.0 without gapping: 250
Number of HSP's successfully gapped in prelim test: 712
Number of HSP's that attempted gapping in prelim test: 3727
Number of HSP's gapped (non-prelim): 1031
length of query: 321
length of database: 30,389,216
effective HSP length: 106
effective length of query: 215
effective length of database: 23,950,988
effective search space: 5149462420
effective search space used: 5149462420
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)