ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2318 good E KOG2467 Amino acid transport and metabolism Glycine/serine hydroxymethyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2318 830410 829004 -469
(469 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR058c [E] KOG2467 Glycine/serine hydroxymethyltransferase 827 0.0
SPAC24C9.12c [E] KOG2467 Glycine/serine hydroxymethyltransferase 667 0.0
SPAC18G6.04c [E] KOG2467 Glycine/serine hydroxymethyltransferase 600 e-171
YBR263w [E] KOG2467 Glycine/serine hydroxymethyltransferase 567 e-161
At4g37930 [E] KOG2467 Glycine/serine hydroxymethyltransferase 561 e-160
Hs19923315 [E] KOG2467 Glycine/serine hydroxymethyltransferase 546 e-155
At5g26780 [E] KOG2467 Glycine/serine hydroxymethyltransferase 546 e-155
CE01130 [E] KOG2467 Glycine/serine hydroxymethyltransferase 543 e-154
At4g32520 [E] KOG2467 Glycine/serine hydroxymethyltransferase 524 e-148
Hs20070176 [E] KOG2467 Glycine/serine hydroxymethyltransferase 523 e-148
7290652 [E] KOG2467 Glycine/serine hydroxymethyltransferase 516 e-146
At4g13930 [E] KOG2467 Glycine/serine hydroxymethyltransferase 470 e-132
At4g13890 [E] KOG2467 Glycine/serine hydroxymethyltransferase 447 e-125
At1g22020 [E] KOG2467 Glycine/serine hydroxymethyltransferase 445 e-125
At1g36370 [E] KOG2467 Glycine/serine hydroxymethyltransferase 430 e-120
ECU01g1420 [E] KOG2467 Glycine/serine hydroxymethyltransferase 423 e-118
ECU01g0190 [E] KOG2467 Glycine/serine hydroxymethyltransferase 423 e-118
>YLR058c [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 469
Score = 827 bits (2135), Expect = 0.0
Identities = 402/469 (85%), Positives = 437/469 (92%)
Query: 1 MPYALSDSHKNLVSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPM 60
MPY LSD+H L+++HL ++DPEV+ IIKDEI+RQKHSI LIASENFTSTSVFDALGTP+
Sbjct: 1 MPYTLSDAHHKLITSHLVDTDPEVDSIIKDEIERQKHSIDLIASENFTSTSVFDALGTPL 60
Query: 61 CNKYSEGYPGARYYGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQ 120
NKYSEGYPGARYYGGNEHIDRME+LCQ+RAL+AF++T DKWGVNVQTLSGSPANLQVYQ
Sbjct: 61 SNKYSEGYPGARYYGGNEHIDRMEILCQQRALKAFHVTPDKWGVNVQTLSGSPANLQVYQ 120
Query: 121 ALMRPHERLMGLFLPDGGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKN 180
A+M+PHERLMGL+LPDGGHLSHGY TENRKISAVSTYFESFPYRV+P+TGIIDYDTLEKN
Sbjct: 121 AIMKPHERLMGLYLPDGGHLSHGYATENRKISAVSTYFESFPYRVNPETGIIDYDTLEKN 180
Query: 181 AILYRPKILVAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYAD 240
AILYRPK+LVAGTSAYCRLIDYKRMREIADK GAYLMVDMAHISGLIAAGVIPSPFEYAD
Sbjct: 181 AILYRPKVLVAGTSAYCRLIDYKRMREIADKCGAYLMVDMAHISGLIAAGVIPSPFEYAD 240
Query: 241 IVTTTTHKSLRGPRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTI 300
IVTTTTHKSLRGPRGAMIFFRRG+RS+NPKTGKE+ YDLE PINFSVFPGHQGGPHNHTI
Sbjct: 241 IVTTTTHKSLRGPRGAMIFFRRGVRSINPKTGKEVLYDLENPINFSVFPGHQGGPHNHTI 300
Query: 301 SALATALKQANTPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVD 360
+ALATALKQA TPEFKEYQTQVLKNAK LE FK LGYRLVS+GTDSHMVLVSLREKGVD
Sbjct: 301 AALATALKQAATPEFKEYQTQVLKNAKALESEFKNLGYRLVSNGTDSHMVLVSLREKGVD 360
Query: 361 GARVEYVCENINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAV 420
GARVEY+CE INIALNKNSIPGDKSALVPGGVRIGAPAMTTRG GE +F RIV YI+KAV
Sbjct: 361 GARVEYICEKINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGMGEEDFHRIVQYINKAV 420
Query: 421 QFAAKTQQSLPKEANKLKDFKAKVNEGSEELTQLKNEIYQWAGEFPLPV 469
+FA + QQSLPK+A +LKDFKAKV+EGS+ L K EIY WAGE+PL V
Sbjct: 421 EFAQQVQQSLPKDACRLKDFKAKVDEGSDVLNTWKKEIYDWAGEYPLAV 469
>SPAC24C9.12c [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 467
Score = 667 bits (1721), Expect = 0.0
Identities = 328/462 (70%), Positives = 379/462 (81%), Gaps = 3/462 (0%)
Query: 8 SHKNLVSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEG 67
S+ +++ L E DP V +I++ E DRQ+ S+VLIASENFTS +V DALG+ M NKYSEG
Sbjct: 3 SNDSIMLTPLKEQDPTVAEIMRHEADRQRSSVVLIASENFTSRAVMDALGSVMSNKYSEG 62
Query: 68 YPGARYYGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHE 127
YPGARYYGGN+ ID++E LCQ+RAL AFNL KWGVNVQ LSGSPAN+QVYQA+M PH
Sbjct: 63 YPGARYYGGNKFIDQIETLCQERALAAFNLDPAKWGVNVQCLSGSPANMQVYQAIMPPHG 122
Query: 128 RLMGLFLPDGGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPK 187
RLMGL LP GGHLSHGYQT+ +KISAVSTYFES PYRVDP TG+IDYD LE +A L+RPK
Sbjct: 123 RLMGLDLPSGGHLSHGYQTDTKKISAVSTYFESMPYRVDPNTGLIDYDMLEHDAQLFRPK 182
Query: 188 ILVAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTH 247
ILVAGTSAYCRLIDY RMR+IAD V AYL+VDMAHISGL++AGVIPSPFEYAD+VTTTTH
Sbjct: 183 ILVAGTSAYCRLIDYARMRQIADSVNAYLVVDMAHISGLVSAGVIPSPFEYADVVTTTTH 242
Query: 248 KSLRGPRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATAL 307
KSLRGPRGAMIFFRRG+R + K G I YDLE INFSVFPGHQGGPHNHTI+ALA AL
Sbjct: 243 KSLRGPRGAMIFFRRGLRK-HDKKGNPIYYDLEDKINFSVFPGHQGGPHNHTITALAVAL 301
Query: 308 KQANTPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYV 367
KQ P +KEYQ QV+KNAKV EE FKK GY+L +DGTDSHMVLV ++ KGVDGAR E V
Sbjct: 302 KQCQEPAYKEYQAQVVKNAKVCEEEFKKRGYKLAADGTDSHMVLVDVKSKGVDGARAERV 361
Query: 368 CENINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQ 427
E INI NKN++P DKSA P G+R+G PAMTTRGF E +F R+VDYID+A+ FAA Q
Sbjct: 362 LELINIVTNKNTVPSDKSAFSPSGIRVGTPAMTTRGFKEQDFVRVVDYIDRALTFAANLQ 421
Query: 428 QSLPKEANKLKDFKAKVNEGSE--ELTQLKNEIYQWAGEFPL 467
+ LPK+ANKLKDFKAK+ EG + EL QL+ E+ +WA FPL
Sbjct: 422 KELPKDANKLKDFKAKLGEGEQYPELVQLQKEVAEWASSFPL 463
>SPAC18G6.04c [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 472
Score = 600 bits (1548), Expect = e-171
Identities = 300/461 (65%), Positives = 361/461 (78%), Gaps = 4/461 (0%)
Query: 12 LVSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGA 71
L+ A L+E DP V +I++ E RQK SI LIASENFTS +V DALG+ M NKYSEGYPGA
Sbjct: 13 LLKAPLAECDPTVYKILESEKSRQKESIALIASENFTSRAVMDALGSIMQNKYSEGYPGA 72
Query: 72 RYYGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERLMG 131
RYYGGNE ID+ E LCQ RALEAF+L +KWGVNVQ SGSPANLQ YQA+M+PH+RLMG
Sbjct: 73 RYYGGNEFIDQAERLCQTRALEAFHLDGEKWGVNVQPHSGSPANLQAYQAVMKPHDRLMG 132
Query: 132 LFLPDGGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKILVA 191
L LP GGHLSHG+ T + ISAVSTYF + PY V+ +TGIIDYD+LEK AI +RPK++VA
Sbjct: 133 LDLPHGGHLSHGFSTPQKAISAVSTYFSTMPYNVNKETGIIDYDSLEKAAIQFRPKVIVA 192
Query: 192 GTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLR 251
G SAY RL+DYKRMR+I + AYL+ DMAHISGL+AAGVIPSPFEYADIVTTTTHKSLR
Sbjct: 193 GASAYARLVDYKRMRKITEMCNAYLLCDMAHISGLVAAGVIPSPFEYADIVTTTTHKSLR 252
Query: 252 GPRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATALKQAN 311
GPRGAMIF+R+G RS + K G I Y+LE INFSVFPGHQGGPHNHTI+ALA AL QA
Sbjct: 253 GPRGAMIFYRKGTRS-HDKRGNPILYELEDKINFSVFPGHQGGPHNHTITALAVALGQAK 311
Query: 312 TPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCENI 371
TPEF +YQ VL NAK + +F GY+LVS GTD+H+VLV L +KGVDGARVE + E +
Sbjct: 312 TPEFYQYQKDVLSNAKAMANAFITRGYKLVSGGTDTHLVLVDLTDKGVDGARVERILELV 371
Query: 372 NIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQQSLP 431
NI+ NKN++PGDKSAL+P G+R+G PA TTRGF E +F R+V+ ID+ V K ++
Sbjct: 372 NISANKNTVPGDKSALIPRGLRLGTPACTTRGFDEKDFERVVELIDEVVSLTKKINEAAL 431
Query: 432 KEA-NKLKDFKAKVNEGSE--ELTQLKNEIYQWAGEFPLPV 469
KE +K +DFKA V +GS+ E+ +LK E+ WAG+F PV
Sbjct: 432 KEGKSKFRDFKAYVGDGSKFSEIAKLKKEVITWAGKFDFPV 472
>YBR263w [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 565
Score = 567 bits (1461), Expect = e-161
Identities = 289/469 (61%), Positives = 352/469 (74%), Gaps = 7/469 (1%)
Query: 5 LSDSHKNLVSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKY 64
L+ ++LVS +SE DPE+ I++ E RQKHSI LI SENFTS +V D LG+ + NKY
Sbjct: 96 LTSGAQSLVSKPVSEGDPEMFDILQQERHRQKHSITLIPSENFTSKAVMDLLGSELQNKY 155
Query: 65 SEGYPGARYYGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMR 124
SEGYPG RYYGGNE ID+ E LCQ RALE + L KWGVNVQ LSG+PANL VY A+M
Sbjct: 156 SEGYPGERYYGGNEIIDKSESLCQARALELYGLDPAKWGVNVQPLSGAPANLYVYSAIMN 215
Query: 125 PHERLMGLFLPDGGHLSHGYQTEN-RKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAIL 183
ERLMGL LPDGGHLSHGYQ ++ IS +S YF+S PY VD TG+IDYD L+ A
Sbjct: 216 VGERLMGLDLPDGGHLSHGYQLKSGTPISFISKYFQSMPYHVDHTTGLIDYDNLQVLAKA 275
Query: 184 YRPKILVAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVT 243
+RPK++VAGTSAY RLIDY R +EI+ GAYLM DMAHISGL+AA V+PSPFE++DIVT
Sbjct: 276 FRPKVIVAGTSAYSRLIDYARFKEISQGCGAYLMSDMAHISGLVAANVVPSPFEHSDIVT 335
Query: 244 TTTHKSLRGPRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISAL 303
TTTHKSLRGPRGAMIFFR+GI+SV K GKEIPY+LE INFSVFPGHQGGPHNHTI A+
Sbjct: 336 TTTHKSLRGPRGAMIFFRKGIKSVTKK-GKEIPYELEKKINFSVFPGHQGGPHNHTIGAM 394
Query: 304 ATALKQANTPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGAR 363
A ALKQA +PEFKEYQ +++ N+K + K+GY+LVS GTD+H++++ L VDGAR
Sbjct: 395 AVALKQAMSPEFKEYQQKIVDNSKWFAQELTKMGYKLVSGGTDNHLIVIDLSGTQVDGAR 454
Query: 364 VEYVCENINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFA 423
VE + +NIA NKN+IPGDKSAL P G+RIG PAMTTRGFG EF+++ YID AV+ A
Sbjct: 455 VETILSALNIAANKNTIPGDKSALFPSGLRIGTPAMTTRGFGREEFSQVAKYIDSAVKLA 514
Query: 424 --AKTQQSLPK--EANKLKDFKAKVNEGSEELTQLKNEIYQWAGEFPLP 468
KT + K ++L +FK NE S E+ L EI +W G++P+P
Sbjct: 515 ENLKTLEPTTKLDARSRLNEFKKLCNE-SSEVAALSGEISKWVGQYPVP 562
>At4g37930 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 517
Score = 561 bits (1447), Expect = e-160
Identities = 275/457 (60%), Positives = 349/457 (76%), Gaps = 6/457 (1%)
Query: 13 VSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGAR 72
++A L E DPE+ II+ E RQ + LI SENFTS SV A+G+ M NKYSEGYPGAR
Sbjct: 51 LNAPLEEVDPEIADIIEHEKARQWKGLELIPSENFTSVSVMQAVGSVMTNKYSEGYPGAR 110
Query: 73 YYGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERLMGL 132
YYGGNE+ID E LCQKRALEAF L +KWGVNVQ LSGSPAN VY AL++PHER+M L
Sbjct: 111 YYGGNEYIDMAETLCQKRALEAFRLDPEKWGVNVQPLSGSPANFHVYTALLKPHERIMAL 170
Query: 133 FLPDGGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKILVAG 192
LP GGHLSHGYQT+ +KISAVS +FE+ PYR+D TG IDYD +EK+A L+RPK++VAG
Sbjct: 171 DLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDESTGYIDYDQMEKSATLFRPKLIVAG 230
Query: 193 TSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRG 252
SAY RL DY R+R++ +K A ++ DMAHISGL+AA VIPSPF+YAD+VTTTTHKSLRG
Sbjct: 231 ASAYARLYDYARIRKVCNKQKAVMLADMAHISGLVAANVIPSPFDYADVVTTTTHKSLRG 290
Query: 253 PRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATALKQANT 312
PRGAMIFFR+G++ +N K GKE+ YD E IN +VFPG QGGPHNHTI+ LA ALKQA T
Sbjct: 291 PRGAMIFFRKGVKEIN-KQGKEVLYDFEDKINQAVFPGLQGGPHNHTITGLAVALKQATT 349
Query: 313 PEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCENIN 372
E+K YQ QVL N+ ++ + GY LVS GTD+H+VLV+L+ KG+DG+RVE V E ++
Sbjct: 350 SEYKAYQEQVLSNSAKFAQTLMERGYELVSGGTDNHLVLVNLKPKGIDGSRVEKVLEAVH 409
Query: 373 IALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQQSLPK 432
IA NKN++PGD SA+VPGG+R+G PA+T+RGF E +FA++ +Y DKAV A K +
Sbjct: 410 IASNKNTVPGDVSAMVPGGIRMGTPALTSRGFVEEDFAKVAEYFDKAVTIALKVKSE--A 467
Query: 433 EANKLKDFKAKVNEGS---EELTQLKNEIYQWAGEFP 466
+ KLKDF + + S E+ +L++E+ ++A +FP
Sbjct: 468 QGTKLKDFVSAMESSSTIQSEIAKLRHEVEEFAKQFP 504
>Hs19923315 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 504
Score = 546 bits (1407), Expect = e-155
Identities = 264/455 (58%), Positives = 352/455 (77%), Gaps = 7/455 (1%)
Query: 17 LSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGARYYGG 76
LS+SDPE+ ++++ E DRQ + LIASENF S + +ALG+ + NKYSEGYPG RYYGG
Sbjct: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108
Query: 77 NEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERLMGLFLPD 136
E +D +ELLCQ+RALEAF+L +WGVNVQ SGSPANL VY AL++PH+R+MGL LPD
Sbjct: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168
Query: 137 GGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKILVAGTSAY 196
GGHL+HGY ++ ++ISA S +FES PY+++PKTG+IDY+ L A L+RP++++AGTSAY
Sbjct: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228
Query: 197 CRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGA 256
RLIDY RMRE+ D+V A+L+ DMAHISGL+AA VIPSPF++ADIVTTTTHK+LRG R
Sbjct: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288
Query: 257 MIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATALKQANTPEFK 316
+IF+R+G+++V+PKTG+EIPY E INF+VFP QGGPHNH I+A+A ALKQA TP F+
Sbjct: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348
Query: 317 EYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCENINIALN 376
EY QVLKNA+ + ++ + GY LVS GTD+H+VLV LR KG+DGAR E V E ++I N
Sbjct: 349 EYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITAN 408
Query: 377 KNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQQSLPKEANK 436
KN+ PGD+SA+ PGG+R+GAPA+T+R F E +F R+VD+ID+ V + + + K
Sbjct: 409 KNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVK----SKTAK 464
Query: 437 LKDFKA---KVNEGSEELTQLKNEIYQWAGEFPLP 468
L+DFK+ K +E S+ L L+ + Q+A FP+P
Sbjct: 465 LQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMP 499
>At5g26780 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 532
Score = 546 bits (1407), Expect = e-155
Identities = 284/487 (58%), Positives = 356/487 (72%), Gaps = 34/487 (6%)
Query: 13 VSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGAR 72
++A L E DPEV II+ E RQ LI SENFTS SV A+G+ M NKYSEGYPGAR
Sbjct: 34 LNASLDEIDPEVADIIELEKARQWKGFELIPSENFTSLSVMQAVGSVMTNKYSEGYPGAR 93
Query: 73 YYGGNEH---------IDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALM 123
YYGGNE+ ID E LCQKRALEAF L KWGVNVQ+LSGSPAN QVY AL+
Sbjct: 94 YYGGNEYVVCILLTRYIDMAETLCQKRALEAFQLDPSKWGVNVQSLSGSPANFQVYTALL 153
Query: 124 RPHERLMGLFLPDGGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAIL 183
+PHER+M L LP GGHLSHGYQT+ +KISAVS +FE+ PYR+D TG IDYD LEK+A+L
Sbjct: 154 KPHERIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDENTGYIDYDQLEKSAVL 213
Query: 184 YRPKILVAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVT 243
+RPK++VAG SAY RL DY R+R++ +K A ++ DMAHISGL+AAGVIPSPFEYAD+VT
Sbjct: 214 FRPKLIVAGASAYARLYDYARIRKVCNKQKAVMLADMAHISGLVAAGVIPSPFEYADVVT 273
Query: 244 TTTHKSLRGPRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISAL 303
TTTHKSLRGPRGAMIFFR+G++ +N K GKE+ YD E IN +VFPG QGGPHNHTI+ L
Sbjct: 274 TTTHKSLRGPRGAMIFFRKGLKEIN-KQGKEVMYDYEDRINQAVFPGLQGGPHNHTITGL 332
Query: 304 ATALKQANTPEFKEYQTQVLKNAKVLEE-------------SFKKL---GYRLVSDGTDS 347
A ALKQA TPE+K YQ QVL+N E S + L GY LVS GTD+
Sbjct: 333 AVALKQARTPEYKAYQDQVLRNCSKFAELDIRPTVIISYGLSMQTLLAKGYDLVSGGTDN 392
Query: 348 HMVLVSLREKGVDGARVEYVCENINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEP 407
H+VLV+L+ KG+DG+RVE V E ++IA NKN++PGD SA+VPGG+R+G PA+T+RGF E
Sbjct: 393 HLVLVNLKNKGIDGSRVEKVLELVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFIEE 452
Query: 408 EFARIVDYIDKAVQFAAKTQ---QSLPKEA--NKLKDFKAKVNEGSE---ELTQLKNEIY 459
+FA++ +Y D AV+ A K + Q + K++ KLKDF A + + E+++L+ +
Sbjct: 453 DFAKVAEYFDLAVKIALKIKAESQGIYKKSFGTKLKDFVATMQSNEKLQSEMSKLREMVE 512
Query: 460 QWAGEFP 466
++A +FP
Sbjct: 513 EYAKQFP 519
>CE01130 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 484
Score = 543 bits (1400), Expect = e-154
Identities = 266/461 (57%), Positives = 342/461 (73%), Gaps = 1/461 (0%)
Query: 8 SHKNLVSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEG 67
+++N++ H+ + DPEV I+K+E RQ+ + LIASENFTS +V DALG+ MCNKYSEG
Sbjct: 20 NNENILVDHVEKVDPEVFDIMKNEKKRQRRGLELIASENFTSKAVMDALGSAMCNKYSEG 79
Query: 68 YPGARYYGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHE 127
YPGARYYGGNE ID+MELLCQKRALE F L KWGVNVQ LSGSPAN VY A++ +
Sbjct: 80 YPGARYYGGNEFIDQMELLCQKRALEVFGLDPAKWGVNVQPLSGSPANFAVYTAIVGSNG 139
Query: 128 RLMGLFLPDGGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPK 187
R+MGL LPDGGHL+HG+ T RK+SA S +F+S PY+VDP TG+IDYD LE+NA+L+RPK
Sbjct: 140 RIMGLDLPDGGHLTHGFFTPARKVSATSEFFQSLPYKVDPTTGLIDYDKLEQNAMLFRPK 199
Query: 188 ILVAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTH 247
++AG S Y R +DY+R R+IA K GAYLM DMAHISGL+AAG+IPSPFEY+D+VTTTTH
Sbjct: 200 AIIAGVSCYARHLDYERFRKIATKAGAYLMSDMAHISGLVAAGLIPSPFEYSDVVTTTTH 259
Query: 248 KSLRGPRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATAL 307
KSLRGPRGA+IF+R+G+RS N K G + YDLE IN +VFPG QGGPHNHTI+ +A AL
Sbjct: 260 KSLRGPRGALIFYRKGVRSTNAK-GVDTLYDLEEKINSAVFPGLQGGPHNHTIAGIAVAL 318
Query: 308 KQANTPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYV 367
+Q + +F +Y QVLKNAK L E KK GY L + GTD+H++LV LR GV+GAR E+V
Sbjct: 319 RQCLSEDFVQYGEQVLKNAKTLAERMKKHGYALATGGTDNHLLLVDLRPIGVEGARAEHV 378
Query: 368 CENINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQ 427
+ +IA NKN+ PGD SAL PGG+R+G PA+T+RGF E +F ++ D+I + VQ A K
Sbjct: 379 LDLAHIACNKNTCPGDVSALRPGGIRLGTPALTSRGFQEQDFEKVGDFIHEGVQIAKKYN 438
Query: 428 QSLPKEANKLKDFKAKVNEGSEELTQLKNEIYQWAGEFPLP 468
K K F +++ L + +++ +F +P
Sbjct: 439 AEAGKTLKDFKSFTETNEPFKKDVADLAKRVEEFSTKFEIP 479
>At4g32520 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 462
Score = 524 bits (1350), Expect = e-148
Identities = 262/456 (57%), Positives = 326/456 (71%), Gaps = 15/456 (3%)
Query: 17 LSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGARYYGG 76
L E DPEV II E DRQ S+ LIASENFTS +V +A+G+ + NKYSEG PG RYYGG
Sbjct: 16 LGEVDPEVRTIITKEKDRQFRSLELIASENFTSRAVMEAVGSCLTNKYSEGLPGKRYYGG 75
Query: 77 NEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERLMGLFLPD 136
NE+ID++E LCQ RAL AF L + KWGVNVQ LSGSPAN VY A++ PH+R+MGL LP
Sbjct: 76 NEYIDQLETLCQNRALAAFRLDSTKWGVNVQPLSGSPANFAVYTAILSPHDRIMGLDLPH 135
Query: 137 GGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKILVAGTSAY 196
GGHLSHG+ T R++S S YFES PYR+D TGI+DYD LEK A L+RPK+++AG SAY
Sbjct: 136 GGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGIVDYDMLEKTATLFRPKLIIAGASAY 195
Query: 197 CRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGA 256
R DY RMR+IAD VGA+LM+DMAHISGL+AA V+ PFEY DIVTTTTHKSLRGPRG
Sbjct: 196 SRDFDYPRMRKIADSVGAFLMMDMAHISGLVAASVVADPFEYCDIVTTTTHKSLRGPRGG 255
Query: 257 MIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATALKQANTPEFK 316
MIFFR+ +P G DLE +N +VFPG QGGPHNHTI LA LK A +PEFK
Sbjct: 256 MIFFRK-----DPING----VDLESAVNNAVFPGLQGGPHNHTIGGLAVCLKHAQSPEFK 306
Query: 317 EYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCENINIALN 376
YQ +V+ N + L +LG++LVS G+D+H+VLV LR G+DGARVE + + +I LN
Sbjct: 307 AYQKRVVSNCRALANRLVELGFKLVSGGSDNHLVLVDLRPMGMDGARVEKILDMASITLN 366
Query: 377 KNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQQSLPKEANK 436
KNS+PGDKSALVPGG+RIG+PAMTTRG E +F + D+I + V+ + +++ P +K
Sbjct: 367 KNSVPGDKSALVPGGIRIGSPAMTTRGLSEKDFVVVADFIKEGVEITMEAKKAAP--GSK 424
Query: 437 LKDFKAKVNEG----SEELTQLKNEIYQWAGEFPLP 468
L+DF V E + LK + + FP+P
Sbjct: 425 LQDFNKFVTSPEFPLKERVKSLKERVETFTSRFPIP 460
>Hs20070176 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 483
Score = 523 bits (1347), Expect = e-148
Identities = 257/466 (55%), Positives = 340/466 (72%), Gaps = 3/466 (0%)
Query: 5 LSDSHKNLVSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKY 64
L SH +++ L +SD EV IIK E +RQ+ + LIASENF S +V +ALG+ + NKY
Sbjct: 14 LWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKY 73
Query: 65 SEGYPGARYYGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMR 124
SEGYPG RYYGG E ID +E LCQKRAL+A+ L WGVNVQ SGSPAN VY AL+
Sbjct: 74 SEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVE 133
Query: 125 PHERLMGLFLPDGGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILY 184
PH R+MGL LPDGGHL+HG+ T+ +KISA S +FES PY+V+P TG I+YD LE+NA L+
Sbjct: 134 PHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLF 193
Query: 185 RPKILVAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTT 244
PK+++AGTS Y R ++Y R+R+IAD+ GAYLM DMAHISGL+AAGV+PSPFE+ +VTT
Sbjct: 194 HPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTT 253
Query: 245 TTHKSLRGPRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALA 304
TTHK+LRG R MIF+R+G++SV+PKTGKEI Y+LE IN +VFPG QGGPHNH I+ +A
Sbjct: 254 TTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVA 313
Query: 305 TALKQANTPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARV 364
ALKQA T EFK YQ QV+ N + L E+ +LGY++V+ G+D+H++LV LR KG DG R
Sbjct: 314 VALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRA 373
Query: 365 EYVCENINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAA 424
E V E +IA NKN+ PGD+SAL P G+R+G PA+T+RG E +F ++ +I + ++
Sbjct: 374 EKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTL 433
Query: 425 KTQQSLPKEANKLKDFKAKV--NEGSEELTQLKNEIYQWAGEFPLP 468
+ Q A LK+FK ++ ++ + L+ E+ +A FPLP
Sbjct: 434 QIQSDTGVRAT-LKEFKERLAGDKYQAAVQALREEVESFASFFPLP 478
>7290652 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 537
Score = 516 bits (1328), Expect = e-146
Identities = 248/462 (53%), Positives = 340/462 (72%), Gaps = 6/462 (1%)
Query: 10 KNLVSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYP 69
+ L+ L++ DPE+ ++IK E +RQ+ + +IASENFTS +V ++L + + NKYSEGYP
Sbjct: 74 QKLLQTPLAQGDPELAELIKKEKERQREGLEMIASENFTSVAVLESLSSCLTNKYSEGYP 133
Query: 70 GARYYGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERL 129
G RYYGGNE+IDR+ELL Q+R E FNL +KWGVNVQ SGSPANL VY + RPH+R+
Sbjct: 134 GKRYYGGNEYIDRIELLAQQRGRELFNLDDEKWGVNVQPYSGSPANLAVYTGVCRPHDRI 193
Query: 130 MGLFLPDGGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKIL 189
MGL LPDGGHL+HG+ T +KISA S +FES PY+V+P+TGIIDYD L + A +RP+I+
Sbjct: 194 MGLDLPDGGHLTHGFFTPTKKISATSIFFESMPYKVNPETGIIDYDKLAEAAKNFRPQII 253
Query: 190 VAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKS 249
+AG S Y RL+DY R R+I D VGAYLM DMAH++G++AAG+IPSPFE+ADIVTTTTHK+
Sbjct: 254 IAGISCYSRLLDYARFRQICDDVGAYLMADMAHVAGIVAAGLIPSPFEWADIVTTTTHKT 313
Query: 250 LRGPRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATALKQ 309
LRGPR +IFFR+G+RS G ++ YDLE IN +VFP QGGPHN+ ++ +ATA KQ
Sbjct: 314 LRGPRAGVIFFRKGVRSTK-ANGDKVLYDLEERINQAVFPSLQGGPHNNAVAGIATAFKQ 372
Query: 310 ANTPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCE 369
A +PEFK YQTQVLKNAK L + GY++ + GTD H+VLV +R+ G+ GA+ EY+ E
Sbjct: 373 AKSPEFKAYQTQVLKNAKALCDGLISRGYQVATGGTDVHLVLVDVRKAGLTGAKAEYILE 432
Query: 370 NINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQQS 429
+ IA NKN++PGDKSA+ P G+R+G PA+TTRG E + ++V +ID A++ Q +
Sbjct: 433 EVGIACNKNTVPGDKSAMNPSGIRLGTPALTTRGLAEQDIEQVVAFIDAALKVG--VQAA 490
Query: 430 LPKEANKLKDFKAKVNEGSE---ELTQLKNEIYQWAGEFPLP 468
+ K+ D+ + E E ++ +++ + Q++ +FPLP
Sbjct: 491 KLAGSPKITDYHKTLAENVELKAQVDEIRKNVAQFSRKFPLP 532
>At4g13930 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 471
Score = 470 bits (1210), Expect = e-132
Identities = 247/450 (54%), Positives = 312/450 (68%), Gaps = 7/450 (1%)
Query: 21 DPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGARYYGGNEHI 80
DPE+ +I+ E RQ I LIASENFTS +V +ALG+ + NKYSEG PG RYYGGNE I
Sbjct: 16 DPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGIPGNRYYGGNEFI 75
Query: 81 DRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERLMGLFLPDGGHL 140
D +E LC+ RALEAF+ WGVNVQ SGSPAN Y AL++PH+R+MGL LP GGHL
Sbjct: 76 DEIENLCRSRALEAFHCDPAAWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHL 135
Query: 141 SHGYQTEN-RKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKILVAGTSAYCRL 199
+HGY T +KISA S YFES PY+V+ TG IDYD LE+ A+ +RPK+L+ G SAY R
Sbjct: 136 THGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKALDFRPKLLICGGSAYPRD 195
Query: 200 IDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGAMIF 259
DY R R IADKVGA L+ DMAHISGL+AA +PFEY D+VTTTTHKSLRGPR MIF
Sbjct: 196 WDYARFRAIADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRAGMIF 255
Query: 260 FRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATALKQANTPEFKEYQ 319
+R+G + + YD E INF+VFP QGGPHNH I ALA ALKQANTP FK Y
Sbjct: 256 YRKGPKPPKKGQPEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPGFKVYA 315
Query: 320 TQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCENINIALNKNS 379
QV NA L GY++V++GT++H+VL LR G+ G +VE +C+ +I LNKN+
Sbjct: 316 KQVKANAVALGNYLMSKGYQIVTNGTENHLVLWDLRPLGLTGNKVEKLCDLCSITLNKNA 375
Query: 380 IPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQQSLPKEANKLKD 439
+ GD SAL PGGVRIGAPAMT+RG E +F +I +++ +AV Q++ K LKD
Sbjct: 376 VFGDSSALAPGGVRIGAPAMTSRGLVEKDFEQIGEFLSRAVTLTLDIQKTYGK---LLKD 432
Query: 440 F-KAKVNEGSEELTQLKNEIYQWAGEFPLP 468
F K VN +++L QLK ++ +++ + +P
Sbjct: 433 FNKGLVN--NKDLDQLKADVEKFSASYEMP 460
>At4g13890 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 470
Score = 447 bits (1149), Expect = e-125
Identities = 231/457 (50%), Positives = 304/457 (65%), Gaps = 7/457 (1%)
Query: 14 SAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGARY 73
+ HL DPE+ +I+ E RQ I LIA+ENFTS +V +ALG+ + NKYSEG PG RY
Sbjct: 9 NTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRY 68
Query: 74 YGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERLMGLF 133
YGG E ID +E LC+ R+LEAF+ +KWGVNVQ SGSPAN Y AL++PH+R+MGL
Sbjct: 69 YGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLD 128
Query: 134 LPDGGHLSHGYQTENRK-ISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKILVAG 192
LP GGH++HGY + K ISA S YFE+ PY+VD KTG IDYD LE+ A+ +RPK+++ G
Sbjct: 129 LPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICG 188
Query: 193 TSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRG 252
++Y R DY R R +ADKVGA+L+ DMAH S L+AA PFEY D+VTT+THKSLRG
Sbjct: 189 GTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRG 248
Query: 253 PRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATALKQANT 312
PR MIF+R+G + + YD + IN +VFP Q GPHN+ I ALA ALKQ
Sbjct: 249 PRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMA 308
Query: 313 PEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCENIN 372
P FK Y QV NA L GY LV+DGTD+H++L LR G+ G +VE VCE
Sbjct: 309 PSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCY 368
Query: 373 IALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQQSLPK 432
I LN+N++ GD S L PGGVRIG PAMT+RG E +F +I +++ +AV Q+ K
Sbjct: 369 ITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGK 428
Query: 433 EANKLKDF-KAKVNEGSEELTQLKNEIYQWAGEFPLP 468
+KDF K VN ++E+ ++K ++ ++ +F +P
Sbjct: 429 ---VMKDFNKGLVN--NKEIDEIKADVEEFTYDFDMP 460
>At1g22020 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 599
Score = 445 bits (1145), Expect = e-125
Identities = 233/458 (50%), Positives = 310/458 (66%), Gaps = 10/458 (2%)
Query: 17 LSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGARYYGG 76
+ E+DPE+ + ++ E RQ I LIASENF +V +ALG+ + NKYSEG PGARYY G
Sbjct: 142 IEEADPEIHEFMEKEKQRQFRGIELIASENFVCRAVMEALGSHLTNKYSEGMPGARYYTG 201
Query: 77 NEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERLMGLFLPD 136
N++ID++E+LCQ+RAL AF L +KWGVNVQ S + AN V+ L+ P ER+MGL P
Sbjct: 202 NQYIDQIEILCQERALAAFGLNHEKWGVNVQPYSCTSANFAVFTGLLMPGERIMGLDSPS 261
Query: 137 GGHLSHGYQTEN-RKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKILVAGTSA 195
GGH+SHGY T +K+S S +FESFPY+VDP+TG IDYD LE+ A+ YRPKIL+ G S+
Sbjct: 262 GGHMSHGYYTPGGKKVSGASIFFESFPYKVDPRTGYIDYDKLEEKALDYRPKILICGGSS 321
Query: 196 YCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRG 255
Y R ++ R R IADK GA LM DMA ISGL+AA P+PF+Y DIVT+TTHKSLRGPRG
Sbjct: 322 YPRDWEFPRFRHIADKCGAVLMFDMAQISGLVAAKESPNPFDYCDIVTSTTHKSLRGPRG 381
Query: 256 AMIFFRRGIR----SVN-PKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATALKQA 310
+IF++RG++ S+N I YD E INFSVFP QGGPHN+ I+ALA ALKQA
Sbjct: 382 GIIFYKRGLKPKKQSINLNHCESNIQYDFEEKINFSVFPSLQGGPHNNHIAALAIALKQA 441
Query: 311 NTPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCEN 370
+PE+K Y QV KNAK L + +L++ GTD+H++L L G+ G E VCE
Sbjct: 442 ASPEYKLYMRQVKKNAKALASALISRKCKLITGGTDNHLLLWDLTPLGLTGKVYEKVCEM 501
Query: 371 INIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQQSL 430
+I +NK +I + + PGGVRIG+PAMT+RG EPEF + D++ +A Q A+ Q
Sbjct: 502 CHITVNKVAIFSENGVISPGGVRIGSPAMTSRGCLEPEFETMADFLYRAAQIASAAQ--- 558
Query: 431 PKEANKLKDFKAKVNEGSEELTQLKNEIYQWAGEFPLP 468
+E KL+ K +E+ L+N++ +A +F +P
Sbjct: 559 -REHGKLQKEPLKSIYHCKEIADLRNQVEAFATQFAMP 595
>At1g36370 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 578
Score = 430 bits (1106), Expect = e-120
Identities = 231/460 (50%), Positives = 305/460 (66%), Gaps = 20/460 (4%)
Query: 20 SDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGARYYGGNEH 79
+DP++ ++++ E RQ I LIASENF +V +ALG+ + NKYSEG PGARYY GN++
Sbjct: 121 ADPDIHELMEKEKQRQVRGIELIASENFVCRAVMEALGSHLTNKYSEGMPGARYYTGNQY 180
Query: 80 IDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERLMGLFLPDGGH 139
ID++E LC +RAL AF L +DKWGVNVQ S + AN VY L+ P ER+MGL P GGH
Sbjct: 181 IDQIENLCIERALTAFGLESDKWGVNVQPYSCTSANFAVYTGLLLPGERIMGLDSPSGGH 240
Query: 140 LSHGYQTEN-RKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKILVAGTSAYCR 198
+SHGY T +KISA S +FESFPY+V+P+TG IDYD LE A+ YRPKIL+ G S+Y R
Sbjct: 241 MSHGYCTPGGKKISAASIFFESFPYKVNPQTGYIDYDKLEDKALDYRPKILICGGSSYPR 300
Query: 199 LIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGAMI 258
D+ R+R+IADK GA LM DMAHISGL+A +PF++ DIVT+TTHK LRGPRG +I
Sbjct: 301 DWDFARVRQIADKCGAVLMCDMAHISGLVATKECSNPFDHCDIVTSTTHKGLRGPRGGII 360
Query: 259 FFRRGIRSVNPKTGKE----------IPYDLEGPINFSVFPGHQGGPHNHTISALATALK 308
F+RRG PK K+ YDLE INF+VFP QGGPHN+ I+ALA ALK
Sbjct: 361 FYRRG-----PKIRKQGHHSSHCDTSTHYDLEEKINFAVFPSLQGGPHNNHIAALAIALK 415
Query: 309 QANTPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVC 368
Q TPE+K Y Q+ KNA+ L + + RLV+ GTD+H++L L G+ G E VC
Sbjct: 416 QVATPEYKAYIQQMKKNAQALAAALLRRKCRLVTGGTDNHLLLWDLTPMGLTGKVYEKVC 475
Query: 369 ENINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQQ 428
E +I LNK +I GD + PGGVRIG PAMTTRG E +F + D++ KA Q +
Sbjct: 476 EMCHITLNKTAIFGDNGTISPGGVRIGTPAMTTRGCIESDFETMADFLIKAAQITS---- 531
Query: 429 SLPKEANKLKDFKAKVNEGSEELTQLKNEIYQWAGEFPLP 468
+L +E K K ++++ +L+N + +A ++ +P
Sbjct: 532 ALQREHGKSHKEFVKSLCTNKDIAELRNRVEAFALQYEMP 571
>ECU01g1420 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 460
Score = 423 bits (1087), Expect = e-118
Identities = 224/460 (48%), Positives = 304/460 (65%), Gaps = 10/460 (2%)
Query: 10 KNLVSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYP 69
K + L +DPE+ +I E++RQK +I LIASEN+ S +A G+ + NKYSEG
Sbjct: 7 KGFWTGPLEMADPELHALICGEVERQKKTINLIASENYAHQSAMEACGSVLTNKYSEGRV 66
Query: 70 GARYYGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERL 129
G RYYGG +DR+ELLCQKRALE F L D WGVNVQ SGSPAN +Y A++ P R+
Sbjct: 67 GERYYGGTHWVDRIELLCQKRALELFGLDPDVWGVNVQPYSGSPANFAIYTAVVPPGGRI 126
Query: 130 MGLFLPDGGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKIL 189
MGL LP GGHL+HGY+T+ RKISA S YF+S PY V G+IDY+ LEK + P IL
Sbjct: 127 MGLDLPSGGHLTHGYKTKTRKISASSVYFDSRPYTVG-SNGLIDYEGLEKTFTDFLPHIL 185
Query: 190 VAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKS 249
+ G SAY R IDYKR++ IA + GA+L D++HIS L+A+G++ SPFE+ DIV TTT K
Sbjct: 186 ICGYSAYSRDIDYKRLQSIAGRNGAFLFADISHISPLVASGLMNSPFEHCDIVMTTTQKG 245
Query: 250 LRGPRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATALKQ 309
LRGPRGA+IF+RR + K G+ + DL+ INF+VFP QGGPHNHTI+ +A+AL
Sbjct: 246 LRGPRGALIFYRRAV----TKNGETV--DLDARINFAVFPMLQGGPHNHTIAGIASALLH 299
Query: 310 ANTPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCE 369
A TPEF EY +V++N++ L + LG +++ GTD+HM+LV LR GVDGA VE++C+
Sbjct: 300 AGTPEFAEYTRRVVENSRELCSRLQSLGLDILTGGTDNHMLLVDLRSTGVDGAAVEHMCD 359
Query: 370 NINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQ-- 427
+ I+LN+N+I G+ S L P G+R+G A+T RGFG E + D I V+ +
Sbjct: 360 ALGISLNRNAIVGNSSPLSPSGIRVGTYAVTARGFGPEEMREVGDIIGGVVKLCREMTGG 419
Query: 428 QSLPKEANKLKDFKAKVNEGSEELTQLKNEIYQWAGEFPL 467
+ + K A+V GSE++ L+ + A +P+
Sbjct: 420 RKMSKADLHRVTSDARV-MGSEQVLVLRRRVCALAEAYPI 458
>ECU01g0190 [E] KOG2467 Glycine/serine hydroxymethyltransferase
Length = 460
Score = 423 bits (1087), Expect = e-118
Identities = 224/460 (48%), Positives = 304/460 (65%), Gaps = 10/460 (2%)
Query: 10 KNLVSAHLSESDPEVEQIIKDEIDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYP 69
K + L +DPE+ +I E++RQK +I LIASEN+ S +A G+ + NKYSEG
Sbjct: 7 KGFWTGPLEMADPELHALICGEVERQKKTINLIASENYAHQSAMEACGSVLTNKYSEGRV 66
Query: 70 GARYYGGNEHIDRMELLCQKRALEAFNLTADKWGVNVQTLSGSPANLQVYQALMRPHERL 129
G RYYGG +DR+ELLCQKRALE F L D WGVNVQ SGSPAN +Y A++ P R+
Sbjct: 67 GERYYGGTHWVDRIELLCQKRALELFGLDPDVWGVNVQPYSGSPANFAIYTAVVPPGGRI 126
Query: 130 MGLFLPDGGHLSHGYQTENRKISAVSTYFESFPYRVDPKTGIIDYDTLEKNAILYRPKIL 189
MGL LP GGHL+HGY+T+ RKISA S YF+S PY V G+IDY+ LEK + P IL
Sbjct: 127 MGLDLPSGGHLTHGYKTKTRKISASSVYFDSRPYTVG-SNGLIDYEGLEKTFTDFLPHIL 185
Query: 190 VAGTSAYCRLIDYKRMREIADKVGAYLMVDMAHISGLIAAGVIPSPFEYADIVTTTTHKS 249
+ G SAY R IDYKR++ IA + GA+L D++HIS L+A+G++ SPFE+ DIV TTT K
Sbjct: 186 ICGYSAYSRDIDYKRLQSIAGRNGAFLFADISHISPLVASGLMNSPFEHCDIVMTTTQKG 245
Query: 250 LRGPRGAMIFFRRGIRSVNPKTGKEIPYDLEGPINFSVFPGHQGGPHNHTISALATALKQ 309
LRGPRGA+IF+RR + K G+ + DL+ INF+VFP QGGPHNHTI+ +A+AL
Sbjct: 246 LRGPRGALIFYRRAV----TKNGETV--DLDARINFAVFPMLQGGPHNHTIAGIASALLH 299
Query: 310 ANTPEFKEYQTQVLKNAKVLEESFKKLGYRLVSDGTDSHMVLVSLREKGVDGARVEYVCE 369
A TPEF EY +V++N++ L + LG +++ GTD+HM+LV LR GVDGA VE++C+
Sbjct: 300 AGTPEFAEYTRRVVENSRELCSRLQSLGLDILTGGTDNHMLLVDLRSTGVDGAAVEHMCD 359
Query: 370 NINIALNKNSIPGDKSALVPGGVRIGAPAMTTRGFGEPEFARIVDYIDKAVQFAAKTQ-- 427
+ I+LN+N+I G+ S L P G+R+G A+T RGFG E + D I V+ +
Sbjct: 360 ALGISLNRNAIVGNSSPLSPSGIRVGTYAVTARGFGPEEMREVGDIIGGVVKLCREMTGG 419
Query: 428 QSLPKEANKLKDFKAKVNEGSEELTQLKNEIYQWAGEFPL 467
+ + K A+V GSE++ L+ + A +P+
Sbjct: 420 RKMSKADLHRVTSDARV-MGSEQVLVLRRRVCALAEAYPI 458
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,822,892
Number of Sequences: 60738
Number of extensions: 1271440
Number of successful extensions: 3516
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 3472
Number of HSP's gapped (non-prelim): 17
length of query: 469
length of database: 30,389,216
effective HSP length: 110
effective length of query: 359
effective length of database: 23,708,036
effective search space: 8511184924
effective search space used: 8511184924
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)