ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2410 good H KOG2794 Coenzyme transport and metabolism Delta-aminolevulinic acid dehydratase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2410 858627 859652 342
(342 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL040c [H] KOG2794 Delta-aminolevulinic acid dehydratase 526 e-149
SPAC1805.06c [H] KOG2794 Delta-aminolevulinic acid dehydratase 349 3e-96
Hs4557297 [H] KOG2794 Delta-aminolevulinic acid dehydratase 311 9e-85
7294597 [H] KOG2794 Delta-aminolevulinic acid dehydratase 265 6e-71
At1g69740 [H] KOG2794 Delta-aminolevulinic acid dehydratase 176 6e-44
At1g44318 [H] KOG2794 Delta-aminolevulinic acid dehydratase 131 1e-30
>YGL040c [H] KOG2794 Delta-aminolevulinic acid dehydratase
Length = 342
Score = 526 bits (1355), Expect = e-149
Identities = 250/340 (73%), Positives = 279/340 (81%)
Query: 2 VHVARFLDERPTDIPSILAGGYNHPLLREWQNERQLTKNMFIFPLFVSDQDDEETIIPSL 61
+H A FL+ PT+I S+LAGGYNHPLLR+WQ+ERQLTKNM IFPLF+SD D+ T I SL
Sbjct: 1 MHTAEFLETEPTEISSVLAGGYNHPLLRQWQSERQLTKNMLIFPLFISDNPDDFTEIDSL 60
Query: 62 PNIKRFGINRLKDYVAGLVAKGLRSVILFGVPLKDGAKDQVATSADDPEGPVIQAIKLLR 121
PNI R G+NRLKDY+ LVAKGLRSVILFGVPL G KD V T+ADDP GPVIQ IK +R
Sbjct: 61 PNINRIGVNRLKDYLKPLVAKGLRSVILFGVPLIPGTKDPVGTAADDPAGPVIQGIKFIR 120
Query: 122 KEFPDLYIICDVCLCEYTSHGHCGVLYEDGTINREKSVQRXXXXXXXXXXXXXHCVAPSD 181
+ FP+LYIICDVCLCEYTSHGHCGVLY+DGTINRE+SV R HCVAPSD
Sbjct: 121 EYFPELYIICDVCLCEYTSHGHCGVLYDDGTINRERSVSRLAAVAVNYAKAGAHCVAPSD 180
Query: 182 MIDGRIREIKMGLIEHGLAHKTFVMSYSAKFSGNLYGPFRDAACSQPGKGDRKCYQLPSX 241
MIDGRIR+IK GLI LAHKTFV+SY+AKFSGNLYGPFRDAACS P GDRKCYQLP
Sbjct: 181 MIDGRIRDIKRGLINANLAHKTFVLSYAAKFSGNLYGPFRDAACSAPSNGDRKCYQLPPA 240
Query: 242 XXXXXXXXXKRDLQEGSDGIIVKPSTFYLDVMSDAAEICRDLPVCAYHVSGEYAMLHAAA 301
+RD+ EG+DGIIVKPSTFYLD+M DA+EIC+DLP+CAYHVSGEYAMLHAAA
Sbjct: 241 GRGLARRALERDMSEGADGIIVKPSTFYLDIMRDASEICKDLPICAYHVSGEYAMLHAAA 300
Query: 302 EKGVVDLKSIAFESHYGFLRAGARLIISYFTPEFLEWLDE 341
EKGVVDLK+IAFESH GFLRAGARLII+Y PEFL+WLDE
Sbjct: 301 EKGVVDLKTIAFESHQGFLRAGARLIITYLAPEFLDWLDE 340
>SPAC1805.06c [H] KOG2794 Delta-aminolevulinic acid dehydratase
Length = 329
Score = 349 bits (896), Expect = 3e-96
Identities = 167/329 (50%), Positives = 226/329 (67%), Gaps = 2/329 (0%)
Query: 12 PTDIPSILAGGYNHPLLREWQNERQLTKNMFIFPLFVSDQDDEETIIPSLPNIKRFGINR 71
P DI S+L GY++PLLREWQ R +TK+ ++P+F+S+ DD + I S+PN R+G+NR
Sbjct: 2 PVDISSLLHAGYSNPLLREWQGVRPITKSSLMYPIFISEIDDAKEAIDSMPNQFRWGVNR 61
Query: 72 LKDYVAGLVAKGLRSVILFGVPLKDGAKDQVATSADDPEGPVIQAIKLLRKEFPDLYIIC 131
L++++ LV KGLRSVILFGV + KD + AD GPVI+A+K +R FP+L + C
Sbjct: 62 LEEFLGPLVKKGLRSVILFGVI--ESKKDYCGSMADSENGPVIKAVKEIRHLFPELVVAC 119
Query: 132 DVCLCEYTSHGHCGVLYEDGTINREKSVQRXXXXXXXXXXXXXHCVAPSDMIDGRIREIK 191
DVCLCEYT HGHCG+LYEDGTIN KSV+R ++PSD +DGR++ IK
Sbjct: 120 DVCLCEYTDHGHCGLLYEDGTINNAKSVERIAEVSGNYALAGAQIISPSDCMDGRVKAIK 179
Query: 192 MGLIEHGLAHKTFVMSYSAKFSGNLYGPFRDAACSQPGKGDRKCYQLPSXXXXXXXXXXK 251
L+E L+HK V+SYSAKF+ +GPFR AA P GDR CYQLP
Sbjct: 180 QKLVELELSHKVCVISYSAKFASGFFGPFRAAANGAPKFGDRSCYQLPCNARGLAKRAIL 239
Query: 252 RDLQEGSDGIIVKPSTFYLDVMSDAAEICRDLPVCAYHVSGEYAMLHAAAEKGVVDLKSI 311
RD++EG+DGI+VKP T YLD+++ A+++ DLP+ Y VSGE+A++HAAA GV +LK
Sbjct: 240 RDVREGADGIMVKPGTPYLDILAMASKLADDLPIATYQVSGEFAIIHAAAAAGVFELKRH 299
Query: 312 AFESHYGFLRAGARLIISYFTPEFLEWLD 340
E+ GF+RAGA ++++YFTPE LEWL+
Sbjct: 300 VMETMDGFMRAGANIVLTYFTPELLEWLE 328
>Hs4557297 [H] KOG2794 Delta-aminolevulinic acid dehydratase
Length = 330
Score = 311 bits (797), Expect = 9e-85
Identities = 157/326 (48%), Positives = 208/326 (63%), Gaps = 2/326 (0%)
Query: 17 SILAGGYNHPLLREWQNERQ-LTKNMFIFPLFVSDQDDEETIIPSLPNIKRFGINRLKDY 75
S+L GY HPLLR WQ L + I+P+FV+D D+ I SLP + R+G+ RL++
Sbjct: 5 SVLHSGYFHPLLRAWQTATTTLNASNLIYPIFVTDVPDDIQPITSLPGVARYGVKRLEEM 64
Query: 76 VAGLVAKGLRSVILFGVPLKDGAKDQVATSADDPEGPVIQAIKLLRKEFPDLYIICDVCL 135
+ LV +GLR V++FGVP + KD+ ++AD E P I+AI LLRK FP+L + CDVCL
Sbjct: 65 LRPLVEEGLRCVLIFGVPSRV-PKDERGSAADSEESPAIEAIHLLRKTFPNLLVACDVCL 123
Query: 136 CEYTSHGHCGVLYEDGTINREKSVQRXXXXXXXXXXXXXHCVAPSDMIDGRIREIKMGLI 195
C YTSHGHCG+L E+G E+S QR VAPSDM+DGR+ IK L+
Sbjct: 124 CPYTSHGHCGLLSENGAFRAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKEALM 183
Query: 196 EHGLAHKTFVMSYSAKFSGNLYGPFRDAACSQPGKGDRKCYQLPSXXXXXXXXXXKRDLQ 255
HGL ++ VMSYSAKF+ YGPFRDAA S P GDR+CYQLP RD++
Sbjct: 184 AHGLGNRVSVMSYSAKFASCFYGPFRDAAKSSPAFGDRRCYQLPPGARGLALRAVDRDVR 243
Query: 256 EGSDGIIVKPSTFYLDVMSDAAEICRDLPVCAYHVSGEYAMLHAAAEKGVVDLKSIAFES 315
EG+D ++VKP YLD++ + + DLP+ YHVSGE+AML A+ G DLK+ E+
Sbjct: 244 EGADMLMVKPGMPYLDIVREVKDKHPDLPLAVYHVSGEFAMLWHGAQAGAFDLKAAVLEA 303
Query: 316 HYGFLRAGARLIISYFTPEFLEWLDE 341
F RAGA +II+Y+TP+ L+WL E
Sbjct: 304 MTAFRRAGADIIITYYTPQLLQWLKE 329
>7294597 [H] KOG2794 Delta-aminolevulinic acid dehydratase
Length = 327
Score = 265 bits (678), Expect = 6e-71
Identities = 142/320 (44%), Positives = 198/320 (61%), Gaps = 4/320 (1%)
Query: 19 LAGGYNHPLLREWQNER-QLTKNMFIFPLFVSDQDDEETIIPSLPNIKRFGINRLKDYVA 77
L G +H LR+ Q ++ + ++P+F+ DD+ I S+P I RFG+NRLK+++
Sbjct: 5 LHSGMHHATLRQLQESGCEIAPHNLMYPVFIVSNDDDVQPIASMPGISRFGLNRLKEHLE 64
Query: 78 GLVAKGLRSVILFGVPLKDGAKDQVATSADDPEGPVIQAIKLLRKEFPDLYIICDVCLCE 137
LVAKGL SV+LFGV D KD+ A++AD + PV+ A+ LR+ FPDL I CDVC+C
Sbjct: 65 PLVAKGLSSVLLFGVVDPD-MKDEQASNADSAKNPVVLALPKLREWFPDLLIACDVCICP 123
Query: 138 YTSHGHCGVLYEDGTINREKSVQRXXXXXXXXXXXXXHCVAPSDMIDGRIREIKMGLIEH 197
Y+SHGHCG+L E G N S++R H VAPSDM+D R++ IK LI+
Sbjct: 124 YSSHGHCGLLGETGLENGP-SIKRIAEIAVAYAKAGAHIVAPSDMMDNRVKAIKQALIDA 182
Query: 198 GLAHKTFVMSYSAKFSGNLYGPFRDAACSQPGKGDRKCYQLPSXXXXXXXXXXKRDLQEG 257
+ + +++YSAKF+ N YGPFR+AA S P GDR+CYQLPS +RD+ EG
Sbjct: 183 QM-NSVSLLAYSAKFTSNFYGPFREAAQSAPKFGDRRCYQLPSGSRSLAMRAIQRDVAEG 241
Query: 258 SDGIIVKPSTFYLDVMSDAAEICRDLPVCAYHVSGEYAMLHAAAEKGVVDLKSIAFESHY 317
+D ++VKP YLD++ + + Y VSGE+AML+ AA+ G DLK E+
Sbjct: 242 ADMLMVKPGMPYLDILRSTKDSYPYHTLYVYQVSGEFAMLYHAAKAGAFDLKDAVLEAMK 301
Query: 318 GFLRAGARLIISYFTPEFLE 337
GF RAGA II+Y+TP L+
Sbjct: 302 GFRRAGADCIITYYTPFLLD 321
>At1g69740 [H] KOG2794 Delta-aminolevulinic acid dehydratase
Length = 430
Score = 176 bits (445), Expect = 6e-44
Identities = 107/310 (34%), Positives = 168/310 (53%), Gaps = 11/310 (3%)
Query: 26 PLLREWQNERQLTKNMFIFPLFVSDQDDEETIIPSLPNIKRFGINR-LKDYVAGLVAKGL 84
P+ R E ++ F++PLF+ + +E+T I ++P R G L VA A G+
Sbjct: 115 PVTRAAFQETDISPANFVYPLFIHE-GEEDTPIGAMPGCYRLGWRHGLVQEVAKARAVGV 173
Query: 85 RSVILFGVPLKDGAKDQVATSADDPEGPVIQAIKLLRKEFPDLYIICDVCLCEYTSHGHC 144
S++LF + + K+ A + G V + I+LL+ ++PDL I DV L Y+S GH
Sbjct: 174 NSIVLFP-KVPEALKNSTGDEAYNDNGLVPRTIRLLKDKYPDLIIYTDVALDPYSSDGHD 232
Query: 145 GVLYEDGTINREKSVQRXXXXXXXXXXXXXHCVAPSDMIDGRIREIKMGLIEHGLAHKTF 204
G++ EDG I +++V + V+PSDM+DGR+ I+ L G + +
Sbjct: 233 GIVREDGVIMNDETVHQLCKQAVSQARAGADVVSPSDMMDGRVGAIRSALDAEGFQNVS- 291
Query: 205 VMSYSAKFSGNLYGPFRDAACSQPGKGDRKCYQLPSXXXXXXXXXXKRDLQEGSDGIIVK 264
+MSY+AK++ + YGPFR+A S P GD+K YQ+ + D EG+D ++VK
Sbjct: 292 IMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALIEAREDEAEGADILLVK 351
Query: 265 PSTFYLDVMSDAAEICRD---LPVCAYHVSGEYAMLHAAAEKGVVDLKSIAFESHYGFLR 321
P YLD++ + RD LP+ AY VSGEY+M+ A ++D + + ES R
Sbjct: 352 PGLPYLDII----RLLRDKSPLPIAAYQVSGEYSMIKAGGVLKMIDEEKVMMESLMCLRR 407
Query: 322 AGARLIISYF 331
AGA +I++YF
Sbjct: 408 AGADIILTYF 417
>At1g44318 [H] KOG2794 Delta-aminolevulinic acid dehydratase
Length = 406
Score = 131 bits (330), Expect = 1e-30
Identities = 93/307 (30%), Positives = 150/307 (48%), Gaps = 11/307 (3%)
Query: 26 PLLREWQNERQLTKNMFIFPLFVSDQDDEETIIPSLPNIKRFGINR-LKDYVAGLVAKGL 84
P R E ++ FI+PLF+ + + + I S+P G L + VA + G+
Sbjct: 92 PTQRAAFQETNISPANFIYPLFIHE-GEVDIPITSMPGRYMLGWRHGLIEEVARALDVGV 150
Query: 85 RSVILFGVPLKDGAKDQVATSADDPEGPVIQAIKLLRKEFPDLYIICDVCLCEYTSHGHC 144
SV L+ + + K A + G + + ++LL+ FPDL I DV EY++ GH
Sbjct: 151 NSVKLYP-KVPEALKSPTGEEAFNDNGLIPRTVRLLKDRFPDLVIYTDVNFDEYSTTGHG 209
Query: 145 GVLYEDGTINREKSVQRXXXXXXXXXXXXXHCVAPSDMIDGRIREIKMGLIEHGLAHKTF 204
G++ EDG I ++++ + V S+M+DGR+ ++ L G
Sbjct: 210 GIVGEDGVILNDETIHQLRKQAVSQARAGADVVCTSEMLDGRVGAVRAALDAEGF-QDVS 268
Query: 205 VMSYSAKFSGNLYGPFRDAACSQPGKGDRKCYQLPSXXXXXXXXXXKRDLQEGSDGIIVK 264
+MSYS K++ +LYG FR D+K YQ+ + D EG+D ++VK
Sbjct: 269 IMSYSVKYTSSLYGRFRKVQL------DKKTYQINPANSREALLEAREDEAEGADILMVK 322
Query: 265 PSTFYLDVMSDAAEICRDLPVCAYHVSGEYAMLHAAAEKGVVDLKSIAFESHYGFLRAGA 324
P+ LD++ + LP+ A VSGEY+M+ AA ++D + + ES RAGA
Sbjct: 323 PALPSLDIIR-LLKNQTLLPIGACQVSGEYSMIKAAGLLKMIDEEKVMMESLLCIRRAGA 381
Query: 325 RLIISYF 331
LI++YF
Sbjct: 382 DLILTYF 388
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.141 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,582,579
Number of Sequences: 60738
Number of extensions: 833707
Number of successful extensions: 1455
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1437
Number of HSP's gapped (non-prelim): 6
length of query: 342
length of database: 30,389,216
effective HSP length: 107
effective length of query: 235
effective length of database: 23,890,250
effective search space: 5614208750
effective search space used: 5614208750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)