ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2412 good R KOG2910 General function prediction only Uncharacterized conserved protein predicted to be involved in protein sorting
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2412 860676 860014 -221
(221 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR077c [R] KOG2910 Uncharacterized conserved protein predicted ... 150 2e-36
Hs13375783 [R] KOG2910 Uncharacterized conserved protein predict... 89 4e-18
7291437 [R] KOG2910 Uncharacterized conserved protein predicted ... 80 3e-15
CE22731 [R] KOG2910 Uncharacterized conserved protein predicted ... 73 4e-13
At5g09260 [R] KOG2910 Uncharacterized conserved protein predicte... 61 1e-09
At5g63880 [R] KOG2910 Uncharacterized conserved protein predicte... 57 2e-08
SPBC215.14c [R] KOG2910 Uncharacterized conserved protein predic... 50 3e-06
7303933 [U] KOG1656 Protein involved in glucose derepression and... 48 9e-06
>YMR077c [R] KOG2910 Uncharacterized conserved protein predicted to be
involved in protein sorting
Length = 221
Score = 150 bits (378), Expect = 2e-36
Identities = 84/224 (37%), Positives = 140/224 (62%), Gaps = 12/224 (5%)
Query: 1 MGQQGSRIKVTESDKAMLQLKMAKDELHRYSRRTENLIGVERAELRTLCIKLKGKQLKQD 60
MGQ+ S++ +T++D+A+L++K +KDE+H+++RRT+NLI VE+++L+ L I+ + K +
Sbjct: 1 MGQKSSKVHITKTDRAILEVKRSKDEIHKFTRRTDNLILVEKSQLKDL-IRKNPENYKSN 59
Query: 61 NRARLLLKRIHYQERLLEQCSDQIINLETMVQSIEFKLIEKKFIDXXXXXXXXXXXXXXX 120
+ R LLKRIHYQE LL+Q SDQ+INLE MV ++EFK++EK+FI+
Sbjct: 60 MKVRFLLKRIHYQEHLLQQASDQLINLENMVSTLEFKMVEKQFIN--GLKNGNEILKKLN 117
Query: 121 XXXXXXXSIMDTAAEQIEIQREIDDALSNAVVG-STINDEVDRELEQLDREVNGTKETAP 179
+MD +QI Q EI++ LS ++VG S D++D+EL+ L+ E+N K
Sbjct: 118 KEFSNVDELMDDVQDQIAYQNEINETLSRSLVGTSNYEDDLDKELDALESELNPEKMN-- 175
Query: 180 GVQDRLDQLPSTKELGEL----KASEPEKENGESQKETPKEEPL 219
++ +PST+ L L + + E+E +++ + +EPL
Sbjct: 176 --NAKVANMPSTEGLPSLPQGEQTEQKEREEFATEERSDTKEPL 217
>Hs13375783 [R] KOG2910 Uncharacterized conserved protein predicted to be
involved in protein sorting
Length = 201
Score = 89.4 bits (220), Expect = 4e-18
Identities = 59/159 (37%), Positives = 85/159 (53%), Gaps = 10/159 (6%)
Query: 9 KVTESDKAMLQLKMAKDELHRYSRRTENLIGVERAELRTLCIKLKGKQLKQDNRARLLLK 68
+VTE DKA+LQLK +D+L +Y +R + ERA R L + + RA+LLLK
Sbjct: 12 RVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLL------RDGRKERAKLLLK 65
Query: 69 RIHYQERLLEQCSDQIINLETMVQSIEFKLIEKKFIDXXXXXXXXXXXXXXXXXXXXXXS 128
+ YQE+LL++ +QI +LE MVQSIEF IE K ++
Sbjct: 66 KKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQLGNECLNKMHQVMSIEEVER 125
Query: 129 IMDTAAEQIEIQREIDDALSNAVVGSTINDEVDRELEQL 167
I+D E +E QR+ID+ L+ GS ++ D LE+L
Sbjct: 126 ILDETQEAVEYQRQIDELLA----GSFTQEDEDAILEEL 160
>7291437 [R] KOG2910 Uncharacterized conserved protein predicted to be
involved in protein sorting
Length = 212
Score = 79.7 bits (195), Expect = 3e-15
Identities = 56/164 (34%), Positives = 80/164 (48%), Gaps = 11/164 (6%)
Query: 9 KVTESDKAMLQLKMAKDELHRYSRRTENLIGVERAELRTLCIKLKGKQLKQDNRARLLLK 68
++T+ DKA+LQLK +D L +Y +R E + +R R K Q + +RA+LLL+
Sbjct: 16 RITDQDKAVLQLKQQRDRLKQYQKRIETQLENDRLLAR------KCLQQGRKDRAKLLLR 69
Query: 69 RIHYQERLLEQCSDQIINLETMVQSIEFKLIEKKFIDXXXXXXXXXXXXXXXXXXXXXXS 128
+ YQE LL Q+ NLE + IEF +E K +D
Sbjct: 70 KKKYQESLLTNADKQLENLEKLAADIEFAQVEMKVLDGLKAGNAALKKVHEMLDIDEVER 129
Query: 129 IMDTAAEQIEIQREIDDALSNAVVGSTINDEVD--RELEQLDRE 170
IMD E IE Q+EID L++ + T DE D EL+ L+ E
Sbjct: 130 IMDETREGIEKQQEIDAILTDVL---TTQDEEDVLAELDALEAE 170
>CE22731 [R] KOG2910 Uncharacterized conserved protein predicted to be
involved in protein sorting
Length = 208
Score = 72.8 bits (177), Expect = 4e-13
Identities = 60/213 (28%), Positives = 100/213 (46%), Gaps = 28/213 (13%)
Query: 10 VTESDKAMLQLKMAKDELHRYSRRTENLIGVERAELRTLCIKLKGKQLKQD---NRARLL 66
V++ D A+L LK +D++ + +R EN + ER KQL +D +RA LL
Sbjct: 17 VSDQDNAILALKTQRDKMKQMIKRKENCLEKERQ---------LAKQLIKDGRKDRALLL 67
Query: 67 LKRIHYQERLLEQCSDQIINLETMVQSIEFKLIEKKFIDXXXXXXXXXXXXXXXXXXXXX 126
LK+ YQE++++Q + + +E MV +EF ++++ D
Sbjct: 68 LKKKRYQEKIIDQTLNHLSKIEQMVNDLEFAEVQQRVTDGLRQGNEALKKMNQLFDIDEI 127
Query: 127 XSIMDTAAEQIEIQREIDDALSNAVVGSTINDEVDRELEQLDREVNGTKETAPGVQDRLD 186
IM+ E E Q EI + LS + + ++D V++ELE L GT + L
Sbjct: 128 DRIMEETKEAAEYQEEISNMLSGQLSNTDVSD-VEKELEDLLAAEWGTVQ--------LP 178
Query: 187 QLPSTKELGELKASEPEKENGESQKETPKEEPL 219
+ PS EL +E E+ + +KE P+ E +
Sbjct: 179 EAPS----HELPEAERER---QKEKEKPRREKI 204
>At5g09260 [R] KOG2910 Uncharacterized conserved protein predicted to be
involved in protein sorting
Length = 216
Score = 61.2 bits (147), Expect = 1e-09
Identities = 55/197 (27%), Positives = 90/197 (44%), Gaps = 22/197 (11%)
Query: 9 KVTESDKAMLQLKMAKDELHRYSRRTENLIGVERAELRTLCIKLKGKQLKQDNRARLLLK 68
K+TE D+A+L LK + +L +Y ++ E +I E+ R L + K+ +RA L LK
Sbjct: 10 KITEVDRAILSLKTQRRKLGQYQQQLEKVIEAEKQAARDLI------REKRKDRALLALK 63
Query: 69 RIHYQERLLEQCSDQIINLETMVQSIEFKLIEKKFIDXXXXXXXXXXXXXXXXXXXXXXS 128
+ QE LL+Q +IN+E + IE +K +
Sbjct: 64 KKRTQEELLKQVDQWLINVEQQLADIELTSKQKAVFESLKQGNNAIKAIQSEVNLDDVQK 123
Query: 129 IMDTAAEQIEIQREIDDALSNAVVGSTINDEVDRE-LEQLDREVNGTKETAPGVQDRLDQ 187
+MD AE Q E+ +A++G ++ E + E L + D E+ V+D + +
Sbjct: 124 LMDDTAEAKAYQDEL-----SAILGEKLSAEDEEEILAEFD-----NLESLLIVED-MPE 172
Query: 188 LPSTKELGELKASEPEK 204
+P+T EL EPEK
Sbjct: 173 VPTT----ELMPEEPEK 185
>At5g63880 [R] KOG2910 Uncharacterized conserved protein predicted to be
involved in protein sorting
Length = 375
Score = 57.4 bits (137), Expect = 2e-08
Identities = 49/202 (24%), Positives = 85/202 (41%), Gaps = 13/202 (6%)
Query: 9 KVTESDKAMLQLKMAKDELHRYSRRTENLIGVERAELRTLCIKLKGKQLKQDNRARLLLK 68
++TE D+A+L LK + +L +Y ++ E +I E+ R L + K+ +RA L L+
Sbjct: 10 QITEVDRAILSLKTQRRKLGQYQQKLEKVIEAEKQAARDLI------REKRKDRALLALR 63
Query: 69 RIHYQERLLEQCSDQIINLETMVQSIEFKLIEKKFIDXXXXXXXXXXXXXXXXXXXXXXS 128
+ QE LL+Q +IN+E + IE +K +
Sbjct: 64 KKRTQEELLKQVDQWVINVEQQLTDIELTSKQKAVFESLKQGNSAIKAIQSELDLDDVQK 123
Query: 129 IMDTAAEQIEIQREIDDALSNAVVGSTIN--DEVDRELEQLDREVNGTKETAPGVQDRLD 186
+MD A+ Q E+ NA++G ++ DE D E + E + P V +
Sbjct: 124 LMDDTADAKAYQDEL-----NAILGEKLSAEDEEDILAEFDNLESQLIVDEMPEVPTKES 178
Query: 187 QLPSTKELGELKASEPEKENGE 208
+ +L ++ P N E
Sbjct: 179 EESEKLDLPDVPTKTPVASNAE 200
>SPBC215.14c [R] KOG2910 Uncharacterized conserved protein predicted to be
involved in protein sorting
Length = 226
Score = 49.7 bits (117), Expect = 3e-06
Identities = 42/168 (25%), Positives = 72/168 (42%), Gaps = 9/168 (5%)
Query: 9 KVTESDKAMLQLKMAKDELHRYSRRTENLIGVERAELRTLCIKLKGKQLKQDNRARL-LL 67
K+ + D+++L +K +D+L RYS+R E + +E ++ C++ D R L L
Sbjct: 7 KINDKDRSILSIKEQRDKLLRYSKRLEKIEQLE-IDIARKCLR------DSDKRGALRAL 59
Query: 68 KRIHYQERLLEQCSDQIINLETMVQSIEFKLIEKKFIDXXXXXXXXXXXXXXXXXXXXXX 127
K L+ Q Q+ N+E ++ +IEF LI+K +
Sbjct: 60 KAKKLYSGLITQTYGQLGNIEQLLSTIEFTLIQKDVMFGLQEGTNLIRQLQADMPLERVG 119
Query: 128 SIMDTAAEQIEIQREIDDALSNAVVGSTINDEVDRELEQLDREVNGTK 175
I + E + E++D L + DE+ EL+ L RE K
Sbjct: 120 RICNDRDEAMSYVDEVNDMLQGR-MSRDQEDEIQEELDSLIREQEDEK 166
>7303933 [U] KOG1656 Protein involved in glucose derepression and
pre-vacuolar endosome protein sorting
Length = 220
Score = 48.1 bits (113), Expect = 9e-06
Identities = 49/181 (27%), Positives = 84/181 (46%), Gaps = 11/181 (6%)
Query: 32 RRTENLIGVERAELRTLC---IKLKGKQLKQDNRARL-LLKRIHYQERLLEQCSDQIINL 87
R TEN++ ++ L + + K ++ R L LK+ E+ L+Q + +
Sbjct: 20 RETENMLIKKQEFLEAKIEDELNIARKNASKNKRVALQALKKKKRLEKQLQQIDGTLSTI 79
Query: 88 ETMVQSIEFKLIEKKFIDXXXXXXXXXXXXXXXXXXXXXXSIMDTAAEQIEIQREIDDAL 147
E +++E + +MD AEQ ++ REI DA+
Sbjct: 80 EMQREALESANTNTAVLTTMKNAADALKRAHQNMDVDKVHDMMDDIAEQQDVAREISDAI 139
Query: 148 SNAVV-GSTINDE-VDRELEQLDREVNGTKETAPGVQDRLDQLPS--TKELGELKASEPE 203
SN V G+ ++DE ++REL++L++E N KE G+ + LP T++L E KA E +
Sbjct: 140 SNPVAFGADLDDEDLERELDELEQE-NFDKEII-GIPEPTPTLPEAPTEDLPE-KAKEKK 196
Query: 204 K 204
K
Sbjct: 197 K 197
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.311 0.130 0.337
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,993,211
Number of Sequences: 60738
Number of extensions: 425550
Number of successful extensions: 2092
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2081
Number of HSP's gapped (non-prelim): 8
length of query: 221
length of database: 30,389,216
effective HSP length: 102
effective length of query: 119
effective length of database: 24,193,940
effective search space: 2879078860
effective search space used: 2879078860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)