ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2415 good E KOG1252 Amino acid transport and metabolism Cystathionine beta-synthase and related enzymes
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2415 861757 863235 493
(493 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR155w [E] KOG1252 Cystathionine beta-synthase and related enzymes 692 0.0
Hs4557415 [E] KOG1252 Cystathionine beta-synthase and related en... 323 5e-88
7295550 [E] KOG1252 Cystathionine beta-synthase and related enzymes 306 6e-83
CE20851 [E] KOG1252 Cystathionine beta-synthase and related enzymes 295 1e-79
CE25661 [E] KOG1252 Cystathionine beta-synthase and related enzymes 276 5e-74
At4g14880 [E] KOG1252 Cystathionine beta-synthase and related en... 183 4e-46
At3g22460 [E] KOG1252 Cystathionine beta-synthase and related en... 177 4e-44
CE08286 [E] KOG1252 Cystathionine beta-synthase and related enzymes 169 1e-41
At2g43750 [E] KOG1252 Cystathionine beta-synthase and related en... 164 4e-40
At5g28020 [E] KOG1252 Cystathionine beta-synthase and related en... 162 1e-39
At3g59760 [E] KOG1252 Cystathionine beta-synthase and related en... 161 2e-39
At5g28030 [E] KOG1252 Cystathionine beta-synthase and related en... 156 6e-38
CE12574 [E] KOG1252 Cystathionine beta-synthase and related enzymes 153 5e-37
CE16252 [E] KOG1252 Cystathionine beta-synthase and related enzymes 153 6e-37
At3g04940 [E] KOG1252 Cystathionine beta-synthase and related en... 151 2e-36
CE11452 [E] KOG1252 Cystathionine beta-synthase and related enzymes 145 1e-34
At3g61440 [E] KOG1252 Cystathionine beta-synthase and related en... 132 2e-30
At3g03630 [E] KOG1252 Cystathionine beta-synthase and related en... 130 3e-30
SPBC36.04 [E] KOG1481 Cysteine synthase 130 4e-30
YGR012w [E] KOG1481 Cysteine synthase 129 8e-30
At1g55880 [E] KOG1481 Cysteine synthase 125 2e-28
SPAC3A12.17c [E] KOG1481 Cysteine synthase 121 2e-27
>YGR155w [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 507
Score = 692 bits (1786), Expect = 0.0
Identities = 351/499 (70%), Positives = 396/499 (79%), Gaps = 10/499 (2%)
Query: 4 DTRHDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEG 63
D+RH+VIDLVGNTPLI L+KLPKA+GIKP++YAKLELYNPGGSIKDRIAKSM+E AE G
Sbjct: 9 DSRHNVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASG 68
Query: 64 IIHPSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPT 123
IHPSRSTLIEPTSGNT KGYRTIITLPEKMSNEKVSVLKALGAEIIRTPT
Sbjct: 69 RIHPSRSTLIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPT 128
Query: 124 AAAWDSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKL 183
AAAWDSPESHIGVA +LEKEIPG +ILDQYNNM NPEAHYFGTG+EI QLEDL+LF L
Sbjct: 129 AAAWDSPESHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNL 188
Query: 184 KAXXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGY 243
+A KY+KEQNDKI IVGADP GSILA PE LN+TD+T+YKVEGIGY
Sbjct: 189 RAVVAGAGTGGTISGISKYLKEQNDKIQIVGADPFGSILAQPENLNKTDITDYKVEGIGY 248
Query: 244 DFVPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELT 303
DFVP+VL+R +D W KTDDK SFKYARQLISNEGVLVGGSSGSAFTA+V YC +HPELT
Sbjct: 249 DFVPQVLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYCEDHPELT 308
Query: 304 EDDVIVVIFPDSVRSYLTKFVDDEWLKTNGLWDDAIATPI--------VQKETDVFEDAT 355
EDDVIV IFPDS+RSYLTKFVDDEWLK N LWDD + K DVF +AT
Sbjct: 309 EDDVIVAIFPDSIRSYLTKFVDDEWLKKNNLWDDDVLARFDSSKLEASTTKYADVFGNAT 368
Query: 356 VKDLNLKPVVSVEEDASVATVIKILRDNSFDQLPVLTKDGKLCG--XXXXXXXXXXXXXX 413
VKDL+LKPVVSV+E A V VIKIL+DN FDQLPVLT+DGKL G
Sbjct: 369 VKDLHLKPVVSVKETAKVTDVIKILKDNGFDQLPVLTEDGKLSGLVTLSELLRKLSINNS 428
Query: 414 XDVSSIKSLFFDFRKLNNFDDISSYNADKSHKKIFVRFDVNTTLSELNSFFEKNSAAIIT 473
+ ++IK + DF+KLNNF+D+SSYN +KS KK F++FD N+ LS+LN FFEKNS+A+IT
Sbjct: 429 NNDNTIKGKYLDFKKLNNFNDVSSYNENKSGKKKFIKFDENSKLSDLNRFFEKNSSAVIT 488
Query: 474 EGLNPVHIVTKVDLLSYLA 492
+GL P+HIVTK+DLLSYLA
Sbjct: 489 DGLKPIHIVTKMDLLSYLA 507
>Hs4557415 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 551
Score = 323 bits (827), Expect = 5e-88
Identities = 195/498 (39%), Positives = 272/498 (54%), Gaps = 45/498 (9%)
Query: 8 DVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHP 67
D++ +G+TP++R+ K+ K G+K ++ AK E +N GGS+KDRI+ MIE AE +G + P
Sbjct: 79 DILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP 138
Query: 68 SRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAW 127
T+IEPTSGNT +GYR II +PEKMS+EKV VL+ALGAEI+RTPT A +
Sbjct: 139 G-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARF 197
Query: 128 DSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAXX 187
DSPESH+GVA RL+ EIP ILDQY N NP AHY T EI Q + KL
Sbjct: 198 DSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCD-----GKLDMLV 252
Query: 188 XXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYDFVP 247
+ +KE+ I+G DP GSILA PE+LN+T+ T Y+VEGIGYDF+P
Sbjct: 253 ASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIP 312
Query: 248 KVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTEDDV 307
VL+R VD W K++D+ +F +AR LI+ EG+L GGS+GS V EL E
Sbjct: 313 TVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQ---ELQEGQR 369
Query: 308 IVVIFPDSVRSYLTKFVDDEWLKTNGLWDDAIATPIVQKETDVFEDATVKDLNLKPVVSV 367
VVI PDSVR+Y+TKF+ D W+ G + T ++ + V++L L ++V
Sbjct: 370 CVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLT----EKKPWWWHLRVQELGLSAPLTV 425
Query: 368 EEDASVATVIKILRDNSFDQLPVLTKDGKLCGXXXXXXXXXXXXXXXDVSSIKSLFFDFR 427
+ I+ILR+ FDQ PV+ + G + G + + SL
Sbjct: 426 LPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLG------------NMLSSLLAG-- 471
Query: 428 KLNNFDDISSYNADKSHKKIFVRFDVNTTLSELNSFFEKNSAAIITEGLNPVH------- 480
K+ D + K K F + + TL L+ E + A++ H
Sbjct: 472 KVQPSDQVG-----KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQ 526
Query: 481 ------IVTKVDLLSYLA 492
+VT +DLL+++A
Sbjct: 527 RQMVFGVVTAIDLLNFVA 544
>7295550 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 522
Score = 306 bits (783), Expect = 6e-83
Identities = 190/493 (38%), Positives = 273/493 (54%), Gaps = 43/493 (8%)
Query: 8 DVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHP 67
++++++G TPL++L +P + GI+ ++YAK E NPGGS+KDRI M++ AEE+G++ P
Sbjct: 48 NILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKP 107
Query: 68 SRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAW 127
T+IEPTSGNT KGY+ II +PEKMSNEKVS L+ LGA+IIRTPT AA+
Sbjct: 108 GY-TIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAY 166
Query: 128 DSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAXX 187
DSPE I VA +L++E P I+LDQY N NP AHY GT EI QL+ +K+
Sbjct: 167 DSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLD-----NKVDMIV 221
Query: 188 XXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYDFVP 247
+ IKEQ IVG DP GSILA P +LN+TDV Y+VEGIGYDF P
Sbjct: 222 VSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPP 281
Query: 248 KVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTEDDV 307
V + VD W K D F +R+L + EG+L GGSSG A A +++ +L +
Sbjct: 282 TVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHAR---KLKKGQR 338
Query: 308 IVVIFPDSVRSYLTKFVDDEWLKTNGLWDDAIATPIVQKETDVFEDATVKDLNL-KPVVS 366
VVI PD +R+Y+TKFV D W++ + V + + + +L L P V
Sbjct: 339 CVVILPDGIRNYMTKFVSDNWMEARNFKEP------VNEHGHWWWSLAIAELELPAPPVI 392
Query: 367 VEEDASVATVIKILRDNSFDQLPVLTK-DGKLCGXXXXXXXXXXXXXXXDVSSIKSLFFD 425
++ DA+V I +++ + DQLPV+ + DG + G V ++L
Sbjct: 393 LKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLG----------------VVGQETLITQ 436
Query: 426 FRKLNNFDDISSYNADKSHKKIFVRFDVNTTLSELNSFFEKNSAAIITEGLNPV------ 479
+N S A K+ K +R + + L +L E + + +I G NP
Sbjct: 437 IVSMNR---QQSDPAIKALNKRVIRLNESEILGKLARVLEVDPSVLIL-GKNPAGKVELK 492
Query: 480 HIVTKVDLLSYLA 492
+ TK+D+ +++A
Sbjct: 493 ALATKLDVTTFIA 505
>CE20851 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 755
Score = 295 bits (754), Expect = 1e-79
Identities = 157/330 (47%), Positives = 205/330 (61%), Gaps = 10/330 (3%)
Query: 9 VIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEG---II 65
V+D +G TPL++LQ +PKA G++ VY K E N GGS KDRIAK M+E AE+ G +
Sbjct: 340 VLDAIGKTPLVKLQHVPKAHGVRCNVYVKCEFLNAGGSTKDRIAKKMVEIAEKTGKPGAL 399
Query: 66 HPSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAA 125
P +TLIEPTSGNT +GY+ +IT+PEKMS EK + L LG+ I+RTP A
Sbjct: 400 TPGATTLIEPTSGNTGIGLSLVAAVRGYKCLITMPEKMSKEKSTTLSVLGSTIVRTPNEA 459
Query: 126 AWDSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKA 185
A++SP SHIGVALRL+ EIPG +ILDQY N NP AHY T +EI + D K+
Sbjct: 460 AFNSPSSHIGVALRLKHEIPGAVILDQYCNPGNPLAHYEETAEEILWDMGD----RKIDL 515
Query: 186 XXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYDF 245
+ I E+ +VG DP GSIL P D Y+VEGIGYDF
Sbjct: 516 VVLGAGTGGTITGISRKIHERRPNAIVVGVDPNGSILTGPTTGPAPDF--YEVEGIGYDF 573
Query: 246 VPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTED 305
+P L+ SVD W+K+DDK SF AR++I EG+L GGSSG A ++ C + +L ED
Sbjct: 574 IPGTLDEKSVDSWLKSDDKESFLMAREIIRTEGILCGGSSGCAVHYALEQCRK-LDLPED 632
Query: 306 DVIVVIFPDSVRSYLTKFVDDEWLKTNGLW 335
+VV+ PD +R+YLTKF+DD+W+K G +
Sbjct: 633 ANVVVLLPDGIRNYLTKFLDDDWMKARGFF 662
Score = 73.2 bits (178), Expect = 9e-13
Identities = 81/320 (25%), Positives = 126/320 (39%), Gaps = 45/320 (14%)
Query: 16 TPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHPSRSTLIEP 75
T L+ L+KL +K +Y KLE N GS++DR A E + GI R +
Sbjct: 21 TQLVPLKKLKAEFQLKSDIYVKLEYLNISGSLEDRAAHRAFEMS--NGI---QRGDEVYV 75
Query: 76 TS-GNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAWDSPESHI 134
T+ G++ KG R P ++ ++L LG +I+ P + + E+ +
Sbjct: 76 TAGGSSAVSYATVAAVKGVRLTAHAPPGAFDQVRTILSTLGTKIVELPVS---NFREARL 132
Query: 135 GVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAXXXXXXXXX 194
L ++ G LD A+ GT EI + ++ L A
Sbjct: 133 QADLLAKRR--GVYNLDGICEKAAFLANLEGTAPEIEKAGKTSAVVVPLDAGGASAAAGI 190
Query: 195 XXXXXXKYIKEQNDKIAIVGADPVGSILA-VPEKLNETDVTEYKVEGIGYDFVPKVLNRD 253
++K+Q K +VG S A P E + +YKVE
Sbjct: 191 AAY----FLKDQ--KTTVVGVRSSASASASAPAPETEVLLQKYKVE-------------- 230
Query: 254 SVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTEDDVIVVIFP 313
D S+ + R LI EG++ G SSG+A + + P V+VV+
Sbjct: 231 ------IRDAPESYTFTRHLIETEGIMAGPSSGAAVLEAIKLAKDLP---AGSVVVVVLM 281
Query: 314 DSVRSYLTKFVDDEWLKTNG 333
D +R YL D +W+K NG
Sbjct: 282 DGIRDYL----DADWMKVNG 297
>CE25661 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 700
Score = 276 bits (706), Expect = 5e-74
Identities = 151/332 (45%), Positives = 201/332 (60%), Gaps = 14/332 (4%)
Query: 9 VIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHPS 68
V+D +G TPL++LQ +PKA G+K VY K E N GGS KDRIAK M+E AE+ G P
Sbjct: 378 VLDAIGKTPLVKLQHIPKAHGVKCNVYVKCEYMNAGGSTKDRIAKRMVEIAEKTG--KPG 435
Query: 69 RS----TLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTA 124
+ TLIEPTSGNT +GY+ IIT+P+KMS EK + +LG+ IIRTP
Sbjct: 436 KLVPGVTLIEPTSGNTGIGLSLASAVRGYKCIITMPKKMSKEKSIAMASLGSTIIRTPNE 495
Query: 125 AAWDSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLK 184
A +DSP SHIGVALRL+ EI ++LDQY N NP AHY T +EI + + D +
Sbjct: 496 AGFDSPHSHIGVALRLKSEIQDAVVLDQYCNPGNPLAHYEETAEEIIYDMGD----KHID 551
Query: 185 AXXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYD 244
+ I E+ +VG DP GSILA P ETD+ Y+VEGIGYD
Sbjct: 552 LVVLTAGTGGTVTGISRKIHERIPTAKVVGVDPHGSILAGPA---ETDIDFYEVEGIGYD 608
Query: 245 FVPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTE 304
F+P L+ ++D+W K+ DK SF AR+LI +EG+L GGSSG A ++ C + L
Sbjct: 609 FLPGTLDTSAIDYWAKSHDKESFLMARELIRSEGILCGGSSGCAVHYALEEC-KSLNLPA 667
Query: 305 DDVIVVIFPDSVRSYLTKFVDDEWLKTNGLWD 336
+ +VV+ PD +R+Y+TKF+DD+W+ D
Sbjct: 668 EANVVVLLPDGIRNYITKFLDDDWMNERHFLD 699
Score = 79.3 bits (194), Expect = 1e-14
Identities = 75/318 (23%), Positives = 129/318 (39%), Gaps = 29/318 (9%)
Query: 16 TPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHPSRSTLIEP 75
TPL+ L+KL ++ +Y KLE N GS++DR A + AEE G++ +
Sbjct: 26 TPLVPLKKLKVEHQLQSDIYVKLEYLNIAGSLEDRTADKAFQFAEEIGVVRGDE--VFVT 83
Query: 76 TSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAWDSPESHIG 135
G+ KG + I P+ + +VL LG + + P E+ +
Sbjct: 84 AGGSAAISYATVAAVKGIKLTIYAPKGEFDLVDTVLHTLGVKTVELPFGTF---AEARVQ 140
Query: 136 VALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAXXXXXXXXXX 195
+++ G L+++ A+ T EI + + S+ K+ A
Sbjct: 141 TDEAAQQK--GVFSLNKFTTNAAFVANLQKTALEIEKAVNNKSI-GKVGAVVIPLNTGAA 197
Query: 196 XXXXXKYIKEQNDK-IAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYDFVPKVLNRDS 254
Y K + + +VG +PE +G D +L +
Sbjct: 198 AAGIAAYYKGIGEHGVRVVGVTCKKD--TIPE--------------MGLDLKNDLLQEYN 241
Query: 255 VDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTEDDVIVVIFPD 314
V+ +D++ + + R LI EG++ G SSG+A + E P IVV+ D
Sbjct: 242 VEKREVEEDEA-YSFTRHLIGTEGIMAGPSSGAAVLEAIKLAKELPA---GSTIVVVLMD 297
Query: 315 SVRSYLTKFVDDEWLKTN 332
+R+YL F+DD+W+ N
Sbjct: 298 GIRNYLRHFLDDDWITAN 315
>At4g14880 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 322
Score = 183 bits (465), Expect = 4e-46
Identities = 119/319 (37%), Positives = 161/319 (50%), Gaps = 17/319 (5%)
Query: 8 DVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHP 67
DV +L+GNTPL+ L + A G +V AKLE+ P S+KDRI SMI AE++G+I P
Sbjct: 8 DVTELIGNTPLVYLNNV--AEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKP 65
Query: 68 SRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAW 127
S LIEPTSGNT KGY+ IIT+P MS E+ +L A G E++ T A
Sbjct: 66 GESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGM 125
Query: 128 DSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAXX 187
+ I A + + P G +L Q+ N NP+ HY TG EI K+
Sbjct: 126 ---KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWK-----GTGGKIDGFV 177
Query: 188 XXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYDFVP 247
KY+KEQN + + G +PV S + L+ +K++GIG F+P
Sbjct: 178 SGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAI-----LSGGKPGPHKIQGIGAGFIP 232
Query: 248 KVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTEDDV 307
VLN D +D V+ S ARQL EG+LVG SSG+A A + + PE +
Sbjct: 233 SVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLA-QRPE-NAGKL 290
Query: 308 IVVIFPDSVRSYLTKFVDD 326
V IFP YL+ + D
Sbjct: 291 FVAIFPSFGERYLSTVLFD 309
>At3g22460 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 321
Score = 177 bits (448), Expect = 4e-44
Identities = 118/320 (36%), Positives = 163/320 (50%), Gaps = 23/320 (7%)
Query: 8 DVIDLVGNTPLIRLQKLPK-AIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIH 66
DV +L+GNTPL+ L K+ K +G V AKLE+ P S+KDRI SMI AE +G+I
Sbjct: 11 DVTELIGNTPLVYLNKVAKDCVG---HVAAKLEMMEPCSSVKDRIGYSMIADAEAKGLIK 67
Query: 67 PSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAA 126
P S LIEPTSGNT KGY+ +IT+P MS E+ +L A GAE+I T A
Sbjct: 68 PGESVLIEPTSGNTGVGLAFTAAAKGYKLVITMPASMSIERRIILLAFGAELILTDPAKG 127
Query: 127 WDSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAX 186
+ + A + + P G +L Q+ N NP+ HY TG EI +
Sbjct: 128 M---KGAVAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEI---------WKGSGGK 175
Query: 187 XXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYDFV 246
KY+KEQN I + G +PV S + L+ +K++GIG F+
Sbjct: 176 VDGFVSGIGTGGAGKYLKEQNTNIKLYGVEPVESPI-----LSGGKPGPHKIQGIGAGFI 230
Query: 247 PKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTEDD 306
P +L+ D +D V+ + S AR L EG+LVG SSG+A TA + + PE
Sbjct: 231 PGILDVDLIDEVVQVSSEESIDMARLLAREEGLLVGISSGAAATAAIKLA-KRPE-NAGK 288
Query: 307 VIVVIFPDSVRSYLTKFVDD 326
+IV +FP YL+ + D
Sbjct: 289 LIVAVFPSFGERYLSTVLFD 308
>CE08286 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 344
Score = 169 bits (427), Expect = 1e-41
Identities = 106/310 (34%), Positives = 160/310 (51%), Gaps = 17/310 (5%)
Query: 12 LVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHPSRST 71
L+GNTP++ + KL K G+ V K+E NP GS+KDRI +M+ AAE++G + P +T
Sbjct: 17 LIGNTPMVYINKLTK--GLPGTVAVKIEYMNPAGSVKDRIGAAMLAAAEKDGTVIPGVTT 74
Query: 72 LIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAWDSPE 131
LIEPTSGNT KGYR I+T+P MS E+ ++LKA G+E++ T A +
Sbjct: 75 LIEPTSGNTGIALAFVAAAKGYRCIVTMPASMSGERRTLLKAYGSEVVLTDPAKGM---K 131
Query: 132 SHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAXXXXXX 191
I +A +L++ IPG IIL Q++N NP HY TG EI Q + + A
Sbjct: 132 GAIDMANQLKENIPGSIILAQFDNPNNPLVHYQTTGPEIWRQTK-----GTVDAVVFGVG 186
Query: 192 XXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYDFVPKVLN 251
+Y++EQN + + +P S + L+ +K++GIG F P VL+
Sbjct: 187 TGGTITGVGRYLQEQNPGVRVFAVEPEESAI-----LSGRPAGPHKIQGIGAGFAPAVLD 241
Query: 252 RDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTEDDVIVVI 311
+ ++ + A++L EG+L G SSG+ A + PE+ +IV
Sbjct: 242 TKIYEDVIRIHSDEAIVMAQRLSYEEGLLGGISSGANVAAALQLA-ARPEMA-GKLIVTC 299
Query: 312 FPDSVRSYLT 321
P Y+T
Sbjct: 300 LPSCGERYMT 309
>At2g43750 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 392
Score = 164 bits (414), Expect = 4e-40
Identities = 106/320 (33%), Positives = 161/320 (50%), Gaps = 17/320 (5%)
Query: 2 GYDTRHDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEE 61
G + + L+G TP++ L + K G V AKLE+ P S+KDRI SMI AEE
Sbjct: 72 GLNIADNAAQLIGKTPMVYLNNVVK--GCVASVAAKLEIMEPCCSVKDRIGYSMITDAEE 129
Query: 62 EGIIHPSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRT 121
+G+I P +S L+E TSGNT KGY+ I+T+P MS E+ +L+A GAE++ T
Sbjct: 130 KGLITPGKSVLVESTSGNTGIGLAFIAASKGYKLILTMPASMSLERRVLLRAFGAELVLT 189
Query: 122 PTAAAWDSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFS 181
A I A + K+ P +L Q++N NP+ HY TG EI
Sbjct: 190 EPAKGMTGA---IQKAEEILKKTPNSYMLQQFDNPANPKIHYETTGPEIWEDTR-----G 241
Query: 182 KLKAXXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGI 241
K+ ++IKE+ ++ ++G +P S + L+ +K++GI
Sbjct: 242 KIDILVAGIGTGGTITGVGRFIKERKPELKVIGVEPTESAI-----LSGGKPGPHKIQGI 296
Query: 242 GYDFVPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPE 301
G FVPK L+ VD ++ + + + ++QL EG+LVG SSG+A A + + PE
Sbjct: 297 GAGFVPKNLDLAIVDEYIAISSEEAIETSKQLALQEGLLVGISSGAAAAAAIQVA-KRPE 355
Query: 302 LTEDDVIVVIFPDSVRSYLT 321
+I V+FP YL+
Sbjct: 356 -NAGKLIAVVFPSFGERYLS 374
>At5g28020 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 323
Score = 162 bits (409), Expect = 1e-39
Identities = 113/327 (34%), Positives = 166/327 (50%), Gaps = 30/327 (9%)
Query: 6 RHDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGII 65
++D+ +L+GNTP++ L + G ++ AKLE+ P S+KDRIA SMI+ AE++G+I
Sbjct: 8 KNDITELIGNTPMVYLNNVVD--GCVARIAAKLEMMEPCSSVKDRIAYSMIKDAEDKGLI 65
Query: 66 HPSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAA 125
P +STLIEPT+GNT +GY+ I+ +P MS E+ +L+ALGAE+
Sbjct: 66 TPGKSTLIEPTAGNTGIGLACMGAARGYKVILVMPSTMSLERRIILRALGAEL------- 118
Query: 126 AWDSPESHIGVALRLEK------EIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSL 179
+ IG+ LEK + PGG I Q+ N NPE HY TG EI
Sbjct: 119 --HLSDQRIGLKGMLEKTEAILSKTPGGYIPQQFENPANPEIHYRTTGPEIWRDSA---- 172
Query: 180 FSKLKAXXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVE 239
K+ K++KEQN I + +PV S + L+ + ++
Sbjct: 173 -GKVDILVAGVGTGGTATGVGKFLKEQNKDIKVCVVEPVESPV-----LSGGQPGPHLIQ 226
Query: 240 GIGYDFVPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEH 299
GIG VP L+ VD ++ + + + A+ L EG+LVG SSG+A A + +
Sbjct: 227 GIGSGIVPFNLDLTIVDEIIQVAGEEAIETAKLLALKEGLLVGISSGAAAAAALKVA-KR 285
Query: 300 PELTEDDVIVVIFPDSVRSYL-TKFVD 325
PE +IVV+FP YL TK D
Sbjct: 286 PE-NAGKLIVVVFPSGGERYLSTKLFD 311
>At3g59760 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 442
Score = 161 bits (407), Expect = 2e-39
Identities = 106/331 (32%), Positives = 165/331 (49%), Gaps = 27/331 (8%)
Query: 2 GYDTRHDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEE 61
G + +V L+G TP++ L + K G + AKLE+ P S+KDRI SM+ AE+
Sbjct: 110 GLNIADNVSQLIGKTPMVYLNSIAK--GCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQ 167
Query: 62 EGIIHPSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRT 121
+G I P +S L+EPTSGNT +GYR I+T+P MS E+ +LKA GAE++ T
Sbjct: 168 KGFISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLT 227
Query: 122 PTAAAWDSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFS 181
A + A + K P +L Q++N NP+ HY TG EI +
Sbjct: 228 DPAKGMTGA---VQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTK-----G 279
Query: 182 KLKAXXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGI 241
K+ ++IKE+N K ++G +P S + L+ +K++GI
Sbjct: 280 KVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTES-----DILSGGKPGPHKIQGI 334
Query: 242 GYDFVPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPE 301
G F+PK L++ +D + + + + A+QL EG++VG SSG+A A + + PE
Sbjct: 335 GAGFIPKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVA-KRPE 393
Query: 302 -------LTEDD----VIVVIFPDSVRSYLT 321
+T ++ V V+FP YL+
Sbjct: 394 NAGKLIAVTVNESMNAVFQVVFPSFGERYLS 424
>At5g28030 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 323
Score = 156 bits (395), Expect = 6e-38
Identities = 109/322 (33%), Positives = 164/322 (50%), Gaps = 29/322 (9%)
Query: 6 RHDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGII 65
++DV +L+GNTP++ L K+ G ++ AKLE+ P SIKDRIA SMI+ AE++G+I
Sbjct: 8 KNDVTELIGNTPMVYLNKIVD--GCVARIAAKLEMMEPCSSIKDRIAYSMIKDAEDKGLI 65
Query: 66 HPSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAA 125
P +STLIE T GNT +GY+ I+ +P MS E+ +L+ALGAE+ T
Sbjct: 66 TPGKSTLIEATGGNTGIGLASIGASRGYKVILLMPSTMSLERRIILRALGAEVHLT---- 121
Query: 126 AWDSPESHIGVALRLEK------EIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSL 179
+ IG+ +LEK + PGG I Q+ N +NPE HY TG EI
Sbjct: 122 -----DISIGIKGQLEKAKEILSKTPGGYIPHQFINPENPEIHYRTTGPEIWRDSA---- 172
Query: 180 FSKLKAXXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVE 239
K+ K++KE+N I + +P S + L+ + ++
Sbjct: 173 -GKVDILVAGVGTGGTVTGTGKFLKEKNKDIKVCVVEPSESAV-----LSGGKPGPHLIQ 226
Query: 240 GIGYDFVPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEH 299
GIG +P L+ VD ++ + + + + L EG+LVG SSG++ A + +
Sbjct: 227 GIGSGEIPANLDLSIVDEIIQVTGEEAIETTKLLAIKEGLLVGISSGASAAAALKVA-KR 285
Query: 300 PELTEDDVIVVIFPDSVRSYLT 321
PE +IVVIFP YL+
Sbjct: 286 PE-NVGKLIVVIFPSGGERYLS 306
>CE12574 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 337
Score = 153 bits (387), Expect = 5e-37
Identities = 101/319 (31%), Positives = 159/319 (49%), Gaps = 22/319 (6%)
Query: 11 DLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHPSRS 70
D +GNTPL+ L+ + K G+ ++ K+E NP S+KDRIAKSM++ AE+ G I P ++
Sbjct: 12 DTIGNTPLVLLRNISK--GLDARIAVKVEYLNPSCSVKDRIAKSMVDEAEKAGTIVPGKT 69
Query: 71 TLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAWDSP 130
L+E TSGN +GY+ I+ +P MS E+ ++L+A GAE+I + D
Sbjct: 70 VLVEGTSGNLGIALAHIGKIRGYKVILVMPATMSVERRAMLRAYGAEVILS------DPA 123
Query: 131 ESHIGVALRLE---KEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAXX 187
E H GV ++E ++P LDQ++N NP AHY TG EI Q E K+
Sbjct: 124 EGHPGVIKKVEMLVDKLPNAHCLDQFSNPANPAAHYRTTGPEIWRQTE-----GKVDIVC 178
Query: 188 XXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYDFVP 247
+Y++EQN I I +P S + L+ +K++GIG VP
Sbjct: 179 FGVGSSGTVTGVGRYLREQNPNIEIYPVEPYESSV-----LSGLPRGPHKIQGIGAGIVP 233
Query: 248 KVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTEDDV 307
++R ++ + + AR+L E +L G SSG+ A V+ + PE +
Sbjct: 234 GNVDRSLFTEILRIKSDDAMQMARRLADEEAILGGISSGANVVAAVELAS-RPENKGKLI 292
Query: 308 IVVIFPDSVRSYLTKFVDD 326
+ + + R + T+ D
Sbjct: 293 VTTVNSFAERYFTTELYSD 311
>CE16252 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 337
Score = 153 bits (386), Expect = 6e-37
Identities = 94/283 (33%), Positives = 146/283 (51%), Gaps = 15/283 (5%)
Query: 11 DLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHPSRS 70
+L+GNTPL++L K+ K +G + K+E NP S+KDRIA +MI+ AE+ G+I P ++
Sbjct: 12 ELIGNTPLLKLNKIGKDLGAS--IAVKVEYMNPACSVKDRIAFNMIDTAEKAGLITPGKT 69
Query: 71 TLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAWDSP 130
LIEPTSGN +GY+ I+T+P MS E+ +LKA GAE+I T A A
Sbjct: 70 VLIEPTSGNMGIALAYCGKLRGYKVILTMPASMSIERRCLLKAYGAEVILTDPATA---V 126
Query: 131 ESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAXXXXX 190
+ + A L IP IL+Q+ N NPEAHY TG EI Q + K+
Sbjct: 127 KGAVQRAEELRDVIPNAYILNQFGNPANPEAHYKTTGPEIWRQTQ-----GKVDIVCFGV 181
Query: 191 XXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYDFVPKVL 250
+++KE+N + + +P S + +N + +K++G+G +P +L
Sbjct: 182 GSGGTCTGVGRFLKEKNPSVQVFPVEPFESSV-----INGLPHSPHKIQGMGTGMIPDIL 236
Query: 251 NRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALV 293
+ ++ + A++L E +L G SSG+ A V
Sbjct: 237 DLTLFSEALRVHSDDAIAMAKKLADEESILGGISSGANVCAAV 279
>At3g04940 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 399
Score = 151 bits (382), Expect = 2e-36
Identities = 100/316 (31%), Positives = 157/316 (49%), Gaps = 17/316 (5%)
Query: 6 RHDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGII 65
+ D L+GNTP++ L + G ++ AKLE+ P S+K+RIA MI+ AE++G+I
Sbjct: 84 KDDATQLIGNTPMVYLNNIVD--GCVARIAAKLEMMEPCSSVKERIAYGMIKDAEDKGLI 141
Query: 66 HPSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAA 125
P +STLIE TSGNT KGY+ ++T+P MS E+ +L ALGAE+ T +
Sbjct: 142 TPGKSTLIEATSGNTGIGLAFIGAAKGYKVVLTMPSSMSLERKIILLALGAEVHLTDPS- 200
Query: 126 AWDSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKA 185
+ I A + + P I+L+Q+ N NP+ HY TG EI ++
Sbjct: 201 --KGVQGIIDKAEEICSKNPDSIMLEQFKNPSNPQTHYRTTGPEIWRDSA-----GEVDI 253
Query: 186 XXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGYDF 245
+++KE+N + G +P S + K + ++GIG
Sbjct: 254 LVAGVGTGGTLSGSGRFLKEKNKDFKVYGVEPTESAVISGGKPG-----THLIQGIGAGL 308
Query: 246 VPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTED 305
+P L+ + +D ++ + + A+ L EG+LVG SSG+A A + + PE
Sbjct: 309 IPDNLDFNVLDEVIQVTSVEAIETAKLLALKEGLLVGISSGAAAAAAIKVA-KRPE-NAG 366
Query: 306 DVIVVIFPDSVRSYLT 321
+IVVIFP YL+
Sbjct: 367 KLIVVIFPSGGERYLS 382
>CE11452 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 337
Score = 145 bits (366), Expect = 1e-34
Identities = 92/291 (31%), Positives = 145/291 (49%), Gaps = 21/291 (7%)
Query: 7 HDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIH 66
HD D VGNTPL+ L+ + K G+ ++ K+E NP S+KDRIAK+M++ AE+ G I
Sbjct: 8 HDSGDTVGNTPLVLLRNITK--GLDARIAVKIEYLNPSCSVKDRIAKTMVDDAEKAGKIV 65
Query: 67 PSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAA 126
P ++ L+E TSGN +GY+ I+ + MS E+ ++L+A GAE+I +
Sbjct: 66 PGKTVLVEGTSGNLGIALAHIGRIRGYKVILVMTTAMSIERRAMLRAYGAEVILS----- 120
Query: 127 WDSPESHIGVALRLE---KEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKL 183
D E H G+ ++E ++P LDQ++N NP AHY TG EI Q + K+
Sbjct: 121 -DPAEGHPGIVKKIEMLVSKLPDAYCLDQFSNPSNPAAHYRTTGPEIWKQTQ-----GKV 174
Query: 184 KAXXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGY 243
+Y++ Q I + +P S + L+ +K+ GIG
Sbjct: 175 DMVCFGVGSGGTVTGVGRYLRAQKQNIGVYPVEPFESSV-----LSGFPRGPHKIHGIGA 229
Query: 244 DFVPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVD 294
+P ++R + + + K AR+L E +L G SSG+ A V+
Sbjct: 230 GLIPGNVDRSLFTEVFRVKSEDAMKMARRLADEEAILGGISSGANVVAAVE 280
>At3g61440 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 368
Score = 132 bits (331), Expect = 2e-30
Identities = 99/328 (30%), Positives = 156/328 (47%), Gaps = 19/328 (5%)
Query: 4 DTRHDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEG 63
+ + D L+G TPL+ L K+ + G + V AK E + P SIKDR A +MI AE++
Sbjct: 48 NAKRDASLLIGKTPLVFLNKVTE--GCEAYVAAKQEHFQPTCSIKDRPAIAMIADAEKKK 105
Query: 64 IIHPSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPT 123
+I P ++TLIEPTSGN KGYR I+T+P S E+ +++ GAE++ T
Sbjct: 106 LIIPGKTTLIEPTSGNMGISLAFMAAMKGYRIIMTMPSYTSLERRVTMRSFGAELVLTDP 165
Query: 124 AAAWDSPESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEI-HHQLEDLSLFSK 182
A + A L P + Q+ N N + H+ TG EI L ++ +F
Sbjct: 166 AKGMGGT---VKKAYDLLDSTPDAFMCQQFANPANTQIHFDTTGPEIWEDTLGNVDIF-- 220
Query: 183 LKAXXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIG 242
+Y+K +N + I G +P S + LN + + G G
Sbjct: 221 ----VMGIGSGGTVSGVGRYLKSKNPNVKIYGVEPAESNI-----LNGGKPGPHAITGNG 271
Query: 243 YDFVPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPEL 302
F P++L+ D ++ ++ + + K AR+L EG++VG SSG+ A + + PE
Sbjct: 272 VGFKPEILDMDVMESVLEVSSEDAIKMARELALKEGLMVGISSGANTVAAIRLA-KMPE- 329
Query: 303 TEDDVIVVIFPDSVRSYLTKFVDDEWLK 330
+ +IV I YL+ + DE K
Sbjct: 330 NKGKLIVTIHASFGERYLSSVLFDELRK 357
>At3g03630 [E] KOG1252 Cystathionine beta-synthase and related enzymes
Length = 404
Score = 130 bits (328), Expect = 3e-30
Identities = 95/318 (29%), Positives = 146/318 (45%), Gaps = 35/318 (11%)
Query: 8 DVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHP 67
DV L+G+TP++ L ++ G + AKLE P S+KDRI SMI AE G I P
Sbjct: 102 DVTQLIGSTPMVYLNRVTD--GCLADIAAKLESMEPCRSVKDRIGLSMINEAENSGAITP 159
Query: 68 SRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAW 127
++ L+EPT+GNT KGY+ I+T+P ++ E+ +L+ALGAEI+ T
Sbjct: 160 RKTVLVEPTTGNTGLGIAFVAAAKGYKLIVTMPASINIERRMLLRALGAEIVLT------ 213
Query: 128 DSPESHIGVALRLEKEI----PGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKL 183
+PE + A+ KEI + Q++N N + H+ TG EI +
Sbjct: 214 -NPEKGLKGAVDKAKEIVLKTKNAYMFQQFDNTANTKIHFETTGPEIWE-----DTMGNV 267
Query: 184 KAXXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSILAVPEKLNETDVTEYKVEGIGY 243
++K N I +VG +P +E V + G
Sbjct: 268 DIFVAGIGTGGTVTGTGGFLKMMNKDIKVVGVEP-----------SERSV----ISGDNP 312
Query: 244 DFVPKVLNRDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELT 303
++P +L+ +D K + + + AR+L EG+LVG SSG+A A V
Sbjct: 313 GYLPGILDVKLLDEVFKVSNGEAIEMARRLALEEGLLVGISSGAAAVAAVSLAKRAENAG 372
Query: 304 EDDVIVVIFPDSVRSYLT 321
+ +I V+FP Y+T
Sbjct: 373 K--LITVLFPSHGERYIT 388
>SPBC36.04 [E] KOG1481 Cysteine synthase
Length = 351
Score = 130 bits (327), Expect = 4e-30
Identities = 101/333 (30%), Positives = 153/333 (45%), Gaps = 18/333 (5%)
Query: 10 IDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGIIHPSR 69
I +G TPLIRL L G + AK E NPGGS+KDR A ++ AE++G +
Sbjct: 18 IGAIGRTPLIRLNTLSNETGCN--ILAKAEFQNPGGSVKDRAAYYVVRDAEKKGKLSRG- 74
Query: 70 STLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAWDS 129
T++E T+GNT +GY+ +I +P S K+ LK LGAE+ P A + +
Sbjct: 75 GTIVEGTAGNTGIGLAHIARARGYKCVIYMPNTQSQAKIDTLKFLGAEVHPVP-VAPFSN 133
Query: 130 PESHIGVALRLEKEIPGGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAXXXX 189
P ++ A R + P DQ++N+ N +HY TG EI Q + +
Sbjct: 134 PLNYNHQARRHAESTPNASWTDQFDNVANLLSHYETTGPEIWDQTK-----GTVDGFTCS 188
Query: 190 XXXXXXXXXXXKYIKEQND-KIAIVGADPVGSILAVPEKL---NETDVTEYKVEGIGYDF 245
KY+KE++D ++A ADP GS+L K + + EGIG
Sbjct: 189 TGTGGTFAGVTKYLKEKSDGRVASFVADPPGSVLYSHIKTKGKHPDNKGSSFTEGIGQGR 248
Query: 246 VPKVLN--RDSVDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELT 303
+ + D +D +K D+ S +L+ EG+ +GGSS A V+ L
Sbjct: 249 ITGNVQPVYDLIDDAMKIPDEKSINMFFRLLDQEGLFLGGSSCLNVVAAVEMAK---ILG 305
Query: 304 EDDVIVVIFPDSVRSYLTKFVDDEWLKTNGLWD 336
+V I DS Y T+ +L++ L+D
Sbjct: 306 PGKTVVTILCDSGHKYATRLFSRSFLESKKLFD 338
>YGR012w [E] KOG1481 Cysteine synthase
Length = 393
Score = 129 bits (325), Expect = 8e-30
Identities = 101/342 (29%), Positives = 163/342 (47%), Gaps = 37/342 (10%)
Query: 6 RHDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEG-I 64
+ V +L+GNTPL++++ L KA G+ +YAKLEL NP GS KDR+A ++I+ AEE G +
Sbjct: 46 KEGVEELIGNTPLVKIRSLTKATGVN--IYAKLELCNPAGSAKDRVALNIIKTAEELGEL 103
Query: 65 IHPSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTA 124
+ + E TSG+T GYR I+LP+ S EK+++L++LGA + + A
Sbjct: 104 VRGEPGWVFEGTSGSTGISIAVVCNALGYRAHISLPDDTSLEKLALLESLGATVNKVKPA 163
Query: 125 AAWDSPESHIGVALRLEKEIP------GGIILDQYNNMKNPEAHYFGTGKEIHHQLEDLS 178
+ D P ++ A + E+ + DQ+ N N + HY TG EI HQ +
Sbjct: 164 SIVD-PNQYVNAAKKACNELKKSGNGIRAVFADQFENEANWKVHYQTTGPEIAHQTK--- 219
Query: 179 LFSKLKAXXXXXXXXXXXXXXXKYIKEQ-NDKIAIVGADPVGSILAVPEKLNETDVTEYK 237
+ A K++KE+ +V ADP GS ++N + +Y
Sbjct: 220 --GNIDAFIAGCGTGGTITGVAKFLKERAKIPCHVVLADPQGS--GFYNRVNYGVMYDYV 275
Query: 238 --------------VEGIGYDFVPK--VLNRDSVDHWVKTDDKSSFKYARQLISNEGVLV 281
VEGIG + + + +D ++ +D + + A+ L N+G+ V
Sbjct: 276 EKEGTRRRHQVDTIVEGIGLNRITHNFHMGEKFIDESIRVNDNQAIRMAKYLSVNDGLFV 335
Query: 282 GGSSGSAFTALVDYCNEHPELTEDDVIVVIFPDSVRSYLTKF 323
G S+ A + P + IV+I DS +L+KF
Sbjct: 336 GSSTAINAVAAIQVAKTLPHGSN---IVIIACDSGSRHLSKF 374
>At1g55880 [E] KOG1481 Cysteine synthase
Length = 421
Score = 125 bits (313), Expect = 2e-28
Identities = 101/385 (26%), Positives = 161/385 (41%), Gaps = 63/385 (16%)
Query: 6 RHDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEGII 65
R+ ++D +GNTPLIR+ L +A G + + K E NPGGS+KDR+A +I+ A E G +
Sbjct: 41 RNGLVDAIGNTPLIRINSLSEATGCE--ILGKCEFLNPGGSVKDRVAVKIIQEALESGKL 98
Query: 66 HPSRSTLIEPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAA 125
P + E ++G+T G + + +P+ + EK +++ALGA + R +
Sbjct: 99 FPG-GIVTEGSAGSTAISLATVAPAYGCKCHVVIPDDAAIEKSQIIEALGASVERVRPVS 157
Query: 126 AWDSPESHIGVALRLEKE---------------------------------------IPG 146
+ ++ +A R E + G
Sbjct: 158 I-THKDHYVNIARRRADEANELASKRRLGSETNGIHQEKTNGCTVEEVKEPSLFSDSVTG 216
Query: 147 GIILDQYNNMKNPEAHYFGTGKEIHHQLEDLSLFSKLKAXXXXXXXXXXXXXXXKYIKEQ 206
G DQ+ N+ N AHY GTG EI HQ + + A ++++++
Sbjct: 217 GFFADQFENLANYRAHYEGTGPEIWHQTQ-----GNIDAFVAAAGTGGTLAGVSRFLQDK 271
Query: 207 NDKIAIVGADPVGSIL------AVPEKLNETDVTEYK------VEGIGYDFVPKVLNRDS 254
N+++ DP GS L V E + K EGIG + + K
Sbjct: 272 NERVKCFLIDPPGSGLYNKVTRGVMYTREEAEGRRLKNPFDTITEGIGINRLTKNFLMAK 331
Query: 255 VDHWVKTDDKSSFKYARQLISNEGVLVGGSSGSAFTALVDYCNEHPELTEDDVIVVIFPD 314
+D + DK + + +R L+ N+G+ VG SS V L IV I D
Sbjct: 332 LDGGFRGTDKEAVEMSRFLLKNDGLFVGSSSAMNCVGAVRVAQ---TLGPGHTIVTILCD 388
Query: 315 SVRSYLTKFVDDEWLKTNGLWDDAI 339
S +L+KF D ++L GL AI
Sbjct: 389 SGMRHLSKFHDPKYLNLYGLSPTAI 413
>SPAC3A12.17c [E] KOG1481 Cysteine synthase
Length = 395
Score = 121 bits (304), Expect = 2e-27
Identities = 102/353 (28%), Positives = 160/353 (44%), Gaps = 33/353 (9%)
Query: 4 DTRHDVIDLVGNTPLIRLQKLPKAIGIKPKVYAKLELYNPGGSIKDRIAKSMIEAAEEEG 63
D + V L+GNT ++R++ L +A G + AK E NPG S KDR+A MI AEE G
Sbjct: 41 DIVNGVEGLIGNTKMVRIKSLSQATGCD--ILAKAEFLNPGNSPKDRVALQMIRTAEENG 98
Query: 64 IIHPSRSTLI-EPTSGNTXXXXXXXXXXKGYRTIITLPEKMSNEKVSVLKALGAEIIRTP 122
+ P +S + E T+G+T GY + I +P S EK +L+ LGA + R
Sbjct: 99 DLVPYQSNAVYEGTAGSTGISIAMLCCSLGYDSRIYMPSDQSKEKSDILELLGAHVQRVT 158
Query: 123 TAAAWDSPESHIGVALR------LEKEIPG-GIILDQYNNMKNPEAHYFGTGKEIHHQLE 175
A D P + A R +++ IPG G +Q+ N N +AH+ TG EI Q
Sbjct: 159 PAPIVD-PNHFVNTARRNAANHTVDESIPGKGYFANQFENPANWQAHFNSTGPEIWRQCA 217
Query: 176 DLSLFSKLKAXXXXXXXXXXXXXXXKYIKEQNDKIAIVGADPVGSIL------AVPEKLN 229
KL A +Y+K ++ I + ADP GS L V L
Sbjct: 218 -----GKLDAFIAGSGTGGTIAGISRYLKSKDPSITVCLADPPGSGLYHKVLHGVMFDLA 272
Query: 230 ETDVTEYK------VEGIGYDFVPK--VLNRDSVDHWVKTDDKSSFKYARQLISNEGVLV 281
E + T + VEG+G + + + + +D + D+ + +R L++++G+ V
Sbjct: 273 EREGTRRRHQVDTIVEGVGINRMTRNFSIAEPLIDMAYRVTDEQAVAMSRYLVTHDGLFV 332
Query: 282 GGSSGSAFTALVDYCNEHPELTEDDVIVVIFPDSVRSYLTKFVDDEWLKTNGL 334
G SS A V +L IV + D + +K ++E+L+ +
Sbjct: 333 GSSSAVNCVAAVRLAK---KLGPGHRIVTLLCDPGSRHFSKLYNEEFLRKKNI 382
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.135 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,228,152
Number of Sequences: 60738
Number of extensions: 1179200
Number of successful extensions: 2178
Number of sequences better than 1.0e-05: 22
Number of HSP's better than 0.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2082
Number of HSP's gapped (non-prelim): 26
length of query: 493
length of database: 30,389,216
effective HSP length: 110
effective length of query: 383
effective length of database: 23,708,036
effective search space: 9080177788
effective search space used: 9080177788
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)