ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2439 good G KOG2533 Carbohydrate transport and metabolism Permease of the major facilitator superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2439 867882 869510 543
(543 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL166c [G] KOG2533 Permease of the major facilitator superfamily 437 e-122
YOL163w [G] KOG2533 Permease of the major facilitator superfamily 226 5e-59
YOL162w [G] KOG2533 Permease of the major facilitator superfamily 223 7e-58
SPAC1002.16c [G] KOG2533 Permease of the major facilitator super... 154 3e-37
SPAC1039.04 [G] KOG2533 Permease of the major facilitator superf... 153 7e-37
SPAC11D3.18c [G] KOG2533 Permease of the major facilitator super... 139 1e-32
YGR260w [G] KOG2533 Permease of the major facilitator superfamily 127 6e-29
SPCC757.13 [G] KOG2533 Permease of the major facilitator superfa... 118 3e-26
SPBC1683.12 [G] KOG2533 Permease of the major facilitator superf... 117 4e-26
SPCC417.10 [G] KOG2533 Permease of the major facilitator superfa... 116 8e-26
SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator super... 113 6e-25
YLR004c [G] KOG2533 Permease of the major facilitator superfamily 105 2e-22
SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator super... 102 1e-21
SPBC1773.15 [G] KOG2533 Permease of the major facilitator superf... 100 4e-21
YAL067c [G] KOG2533 Permease of the major facilitator superfamily 95 3e-19
YLL055w [G] KOG2533 Permease of the major facilitator superfamily 90 1e-17
YJR152w [G] KOG2533 Permease of the major facilitator superfamily 88 3e-17
YGR065c [G] KOG2533 Permease of the major facilitator superfamily 82 2e-15
SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superf... 80 8e-15
SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superf... 79 2e-14
SPAC1B3.15c [G] KOG2533 Permease of the major facilitator superf... 72 3e-12
YCR028c [G] KOG2533 Permease of the major facilitator superfamily 63 1e-09
>YIL166c [G] KOG2533 Permease of the major facilitator superfamily
Length = 542
Score = 437 bits (1124), Expect = e-122
Identities = 220/531 (41%), Positives = 332/531 (62%), Gaps = 3/531 (0%)
Query: 13 VKRISLSSYDVELRSQDSLDSDNPFSDPLIAEYYRALYEESKYESRSAFDPAFXXXXXXX 72
V++ LS L S S NPF D AE +R +YE S YE S FDP F
Sbjct: 11 VEKAQLSVSAESLTSDSESISHNPFDDFHKAERWRKVYESSGYEGLSKFDPEFTWTKDEE 70
Query: 73 XXXXXXXNFRVAFVACFLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFF 132
+ ++ +F L L R N+++AV+DN + DL M+TND+NLG ++ + F
Sbjct: 71 KKLVRKMDLKIFLWVFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYNLGQTVYLVIFL 130
Query: 133 LAELPSQLISKRLGPDIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADL 192
+ELP L+SKR GP+ IP+QI WSV+ + QA + N+ F+ RCL+G ++GGFI D
Sbjct: 131 ASELPGNLLSKRFGPERVIPVQIVLWSVICITQAGLKNRGQFIATRCLLGMVQGGFIPDN 190
Query: 193 VLWLTYFFTSKELSIRLSWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGIL 252
+L+L+Y++T EL+ RLS+FW ++ + Q++ +LLA GI+ MRGI LAGWQYLF++EG L
Sbjct: 191 ILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYLFIIEGFL 250
Query: 253 TFLIGLSGFYLMVPGAVQTKNWMHPKG--WFTEREEKIVVNRVLRDDPSKGDMHNRQPIS 310
+ +G++ FYLM G QT KG FTE EEKI+VNR+LRDDPSKGDM NRQP++
Sbjct: 251 SLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGDMSNRQPVT 310
Query: 311 FKLLWSAISDYDLWPIYLIGLIAYVPMNTVSTYLTLTLKSVGFSTLNVQLLSIPYQVIHI 370
FK + ++++DLWP+++ G+ A++ + TV +YL+L LKS+ +ST +L+IP Q + +
Sbjct: 311 FKEILYTLTEFDLWPLFIQGITAFISLQTVGSYLSLILKSLNYSTFLSNILAIPGQALLL 370
Query: 371 TLLIGVTWYAERIDQRAYMGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYV 430
L + ++ +++ IA++W F+ L W + L T +LG PY
Sbjct: 371 INLPLAALLSRKLKEKSLCVGIANVWVLPFIVSLVALPTD-TNPWIKYILLTGILGLPYT 429
Query: 431 HAICVSWVSRNSNSIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVLFAISI 490
H+I WVS SNS+++R + +ALYNM+ QVGAI ++ +YR +D P Y GN +L +
Sbjct: 430 HSILAGWVSEISNSVRSRTVGTALYNMSAQVGAIIASNMYRNDDKPYYTRGNKILLGFTC 489
Query: 491 AGIPVFLFAKWYYRTRNKRKEAIWSQMSEDERVEYIQTTSDQANKRLDFRF 541
I + + K+YY +RNK K+ W+ M+++E++ Y+ TT D+ KRLD+RF
Sbjct: 490 FNICMAVATKFYYISRNKYKDRKWNSMTKEEQINYLDTTKDKGMKRLDYRF 540
>YOL163w [G] KOG2533 Permease of the major facilitator superfamily
Length = 169
Score = 226 bits (577), Expect = 5e-59
Identities = 99/165 (60%), Positives = 133/165 (80%)
Query: 157 AWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTSKELSIRLSWFWTSL 216
AWS+VA Q M K+ F CR L+G EGGF+ADLVLW++YF++S ELSIRLS+FW +L
Sbjct: 3 AWSLVATLQCKMTGKSSFYTCRALMGLFEGGFVADLVLWMSYFYSSSELSIRLSFFWVTL 62
Query: 217 SIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLSGFYLMVPGAVQTKNWMH 276
S+ Q++++++A+G+ MRGIGG+AGWQ+LFL+E I T +IG+S ++LMVP VQTK
Sbjct: 63 SLTQIITSIVAFGVFHMRGIGGMAGWQWLFLIERIFTLVIGISAYFLMVPSVVQTKKPWS 122
Query: 277 PKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISDY 321
KGWFTEREEKI+VN++LRDDP+KGDM+NRQ +S K+LW I+DY
Sbjct: 123 KKGWFTEREEKIIVNKILRDDPTKGDMNNRQGMSLKMLWQGITDY 167
>YOL162w [G] KOG2533 Permease of the major facilitator superfamily
Length = 215
Score = 223 bits (567), Expect = 7e-58
Identities = 103/213 (48%), Positives = 148/213 (69%)
Query: 329 IGLIAYVPMNTVSTYLTLTLKSVGFSTLNVQLLSIPYQVIHITLLIGVTWYAERIDQRAY 388
+GL+AY+P N ++TYLTL L+S+GF+T LL+IP V+HI LL G+TW E+ + R
Sbjct: 1 MGLLAYIPTNVLATYLTLVLRSIGFTTFQANLLAIPNFVLHILLLFGLTWSTEKCNNRLG 60
Query: 389 MGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYVHAICVSWVSRNSNSIKTR 448
+ ++ ++ L VLR+WKG++ W T+A+ TL+L PY+HAICVS SRNS S+KTR
Sbjct: 61 LSLLQPLYTVPLLAVLRFWKGTMFNKWGTYAIITLILDNPYIHAICVSLCSRNSQSVKTR 120
Query: 449 ALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVLFAISIAGIPVFLFAKWYYRTRNK 508
+S+ LYNM VQ G I S+ IY K+DAPLY GN VLF +++ P+ + +K Y NK
Sbjct: 121 TVSTCLYNMFVQAGLIISSNIYAKSDAPLYRKGNGVLFGLALFMFPILIGSKLIYVYINK 180
Query: 509 RKEAIWSQMSEDERVEYIQTTSDQANKRLDFRF 541
+++ W+ MSE+E+ Y+ TTSD ++RLDFRF
Sbjct: 181 QRDKRWNAMSEEEKDHYLSTTSDAGSRRLDFRF 213
>SPAC1002.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 499
Score = 154 bits (389), Expect = 3e-37
Identities = 113/453 (24%), Positives = 221/453 (47%), Gaps = 24/453 (5%)
Query: 90 LFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLISKRLGPDI 149
L++ LDR N+ A L EDL + + FN+ +FY++F L E+P+ L+ K++ P
Sbjct: 66 LYLVAFLDRSNIGNAKVAGLPEDLKLKGDQFNIIASVFYVTFILFEMPTTLLMKKVQPKR 125
Query: 150 FIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTSKELSIRL 209
+ + ++S+ + HN G L R ++G E G L L+LT ++ EL+ R+
Sbjct: 126 MLAFIVISYSLTTIFTGFCHNFGGLLAARLVLGFCEAGLFPCLALYLTMIYSRVELAPRI 185
Query: 210 SWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLSGFYLMVPGAV 269
++ + S ++ L AY +L M G+GG AGW++LF++EG++ F+ G++ Y ++P +
Sbjct: 186 AYLFASSALSGAFGGLFAYAVLHMDGVGGFAGWRWLFIIEGLIGFVCGVA-VYFIIPNDI 244
Query: 270 QTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISDYDLWPIYLI 329
TK W + ++ ++++ R L H +K + SA +D+ ++ L
Sbjct: 245 -TKAW-----FLSKTHQEMMRKRQLERAADLEAAH----FDWKGVKSAFTDFKVYLYALS 294
Query: 330 GLIAYVPMNTVSTYLTLTLKSVGFSTLNVQLLSIPYQVIHITLLIGVTWYAERIDQRAYM 389
+ ST+L + +G+++L+VQ ++IP ++ I ++ ++R R +
Sbjct: 295 EFGQDTCLYGFSTFLPAIISGMGYTSLSVQYMTIPVYILGAATYIAASFLSDRFHHRGII 354
Query: 390 GVIASIWNAL-FLGVLRWWKGSLVEAWPTFALCTLLLGGPYVHA-ICVSWVSRNSNSIKT 447
+I +I+ + ++ +L V + C L G Y A + V+W+S N
Sbjct: 355 LIIGNIFPIVGYILLLACQNNKSV----LYFACYLCSVGVYTGAGLNVTWLSANIAPHYK 410
Query: 448 RALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGN-TVLFAISIAGIPVFLFAKWYYRTR 506
RA + +L I + QIYR P Y G+ T L AI I+ + + + ++ + +
Sbjct: 411 RATAISLQLAIANSSGILAGQIYRY--PPKYIAGHLTSLIAIFISTV-LHVVNIFFLKHQ 467
Query: 507 NKRKEAIWSQMSEDERVEYIQTTSDQANKRLDF 539
N +K+ ++ ++ + D + R +
Sbjct: 468 NSKKQ---KSLASSSTIDLSEQPKDDKDARFHY 497
>SPAC1039.04 [G] KOG2533 Permease of the major facilitator superfamily
Length = 507
Score = 153 bits (386), Expect = 7e-37
Identities = 110/430 (25%), Positives = 211/430 (48%), Gaps = 28/430 (6%)
Query: 80 NFRVAFVACFLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQ 139
+FR+ + L++ LD+ N+S A + + +DL + +N+ +FY+ F L P
Sbjct: 58 DFRILPLLALLYLFNALDKSNVSNAKTNGMDKDLGFVGDQYNIMISIFYIPFVLCAFPFS 117
Query: 140 LISKRLGPDIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYF 199
+ KR G +P + ++ +++ QAA+ N G + R +G E + +V +LT F
Sbjct: 118 YLYKRFGAARILPFFMLSFGAMSLCQAAVKNFGGMMAVRWFLGMAESAVLPGVVYYLTTF 177
Query: 200 FTSKELSIRLSWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLS 259
+ EL+ RL+ F+ + ++ LLAYG+ ++G G L GWQYLFL+EG +TFL +
Sbjct: 178 YRRTELARRLAIFYAAANVSSAFGGLLAYGVFHIKG-GKLQGWQYLFLIEGGVTFLCAIV 236
Query: 260 GFYLMVPGAVQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAIS 319
+L++P +V+T N++ T+ E+ + R+ D S IS KL +
Sbjct: 237 -IFLVLPVSVETANFL------TDEEKTLAKMRIENDSSS--------AISEKLSFKQSL 281
Query: 320 DYDLWPIYLIGLIAY----VPMNTVSTYLTLTLKSVGFSTLNVQLLSIPYQVIHITLLIG 375
PI ++ L+ VP+N+++ +L + ++GFS++N L+++ + L+
Sbjct: 282 TVFKHPIAILWLLEEMALGVPLNSINNWLPQIVAAMGFSSVNTNLMTVAPAISGAIWLLV 341
Query: 376 VTWYAERIDQRAYMGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYVHAICV 435
+ ++ + R + +IA+I + ++ + ++ C L+ G ++
Sbjct: 342 FAFISDFLKNRGIV-LIAAISTTMIGFIVYGSIDIMNHIGVSYFACFLMTAGAAASSVLT 400
Query: 436 S-WVSRNSNSIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLY------HTGNTVLFAI 488
S W + N+ + RA+ +++ V + S I+R DAP Y G L +
Sbjct: 401 STWYNNNTPNESRRAVFTSVGVPLANVMGLVSANIFRPQDAPKYVPALGITAGFGGLGIL 460
Query: 489 SIAGIPVFLF 498
+A I V++F
Sbjct: 461 LVASISVYMF 470
>SPAC11D3.18c [G] KOG2533 Permease of the major facilitator superfamily
Length = 498
Score = 139 bits (350), Expect = 1e-32
Identities = 103/423 (24%), Positives = 185/423 (43%), Gaps = 15/423 (3%)
Query: 89 FLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLISKRLGPD 148
FL++ LDR N+ A + E L + N+ +FY+ + L E PS ++ KR+
Sbjct: 67 FLYLMAFLDRSNIGNAAVAGMTEALSLYGERLNVAVSIFYVLYILVETPSVVLVKRIKAS 126
Query: 149 IFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTSKELSIR 208
+ AWS+ + M + G + R ++G LEG L L+LT +T KE R
Sbjct: 127 RMLAFISFAWSMTVLFSGFMSSYGGLIATRLILGLLEGCLFPALNLYLTTHYTRKEQCQR 186
Query: 209 LSWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLSGFYLMVPGA 268
LS+ + S + L AY + ++ G GWQ+++++EG+++F IG+ +P
Sbjct: 187 LSYLFASAGLAGAFGGLFAYALEQVHA-GNKEGWQWIYIVEGLVSF-IGVPLCLFALPDK 244
Query: 269 VQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISDYDLWPIYL 328
++ WF REE+ V ++R D H Q + + A D ++
Sbjct: 245 ME-------NAWFLTREEREVA--IIRRD-INARYHGEQHFEWSEVRKAFKDPKVYVSAT 294
Query: 329 IGLIAYVPMNTVSTYLTLTLKSVGFSTLNVQLLSIPYQVIHITLLIGVTWYAERIDQRAY 388
A + + S++L + +K +GF L ++IP + + + V W ++R RA
Sbjct: 295 SQFCADMVLYGFSSFLPVIIKGLGFVGLQTNYMTIPVYIAGVISFLFVAWLSDRTQLRAV 354
Query: 389 MGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYVHAICVSWVSRNSNSIKTR 448
+ AS A+ ++ + + T+ + GP + + W++ N R
Sbjct: 355 YLISASTVVAVGYIIMLASDSNAAKYTATYIIAIGCYIGP---GLNLGWLNNNVAGHYKR 411
Query: 449 ALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVLFAISIAGIPVFLFAKWYYRTRNK 508
A + + I + QIYR +AP Y GN I G ++ + R NK
Sbjct: 412 ATAIGIQQTLANSSGIVAGQIYRSKNAPKYILGNAFTLGCVIVGGLAYVVMFFSLRYVNK 471
Query: 509 RKE 511
+++
Sbjct: 472 KRD 474
>YGR260w [G] KOG2533 Permease of the major facilitator superfamily
Length = 534
Score = 127 bits (318), Expect = 6e-29
Identities = 101/450 (22%), Positives = 211/450 (46%), Gaps = 29/450 (6%)
Query: 90 LFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLISKRLGPDI 149
L+ LD+ N+ A L +D+H+ +N +F+ ++ L + + K +GP +
Sbjct: 99 LYFLSNLDKSNIGNAEVAGLSKDIHLVGTQYNTCVTVFFATYVLFDPIGTNLLKIMGPPL 158
Query: 150 FIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTSKELSIRL 209
+ I + + +++ A + N A ++ R L+GA EG + ++L+ + ++ ++R
Sbjct: 159 MMSICLTCFGAISLGTAWVKNYAQLIVVRLLLGAFEGMIYPAINMYLSVCYRREQYALRF 218
Query: 210 SWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLSGFYLMVPGAV 269
++ +++ + L+AYG ++ G L WQY++++EG ++ +G FY
Sbjct: 219 AFVFSAACLSSSFGGLIAYGCSKIS--GSLKDWQYIYIVEGCIS--LGFVPFYAF----G 270
Query: 270 QTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISDYDLW--PIY 327
+KN WF +EEK ++ + + + + +W A+ D W +
Sbjct: 271 LSKNL--EDSWFFNKEEKEYISERYK---TMNTFDPDEKFEWFQVWQAVKDVKTWASAVA 325
Query: 328 LIGLIAYVPMNT--VSTYLTLTLKSVGFSTLNVQLLSIP-YQVIHITLLIGVTWYAERID 384
L G + + T ++ +L + + S+GF+ + QL+++P Y + I I W ++RI
Sbjct: 326 LFG----IDLTTFGLTVFLPIIITSMGFTNVRAQLMTVPIYFLTAIVFFICAVW-SDRIK 380
Query: 385 QRAYMGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYVHAIC-VSWVSRNSN 443
R+ + A + ++ + ++ + V + + LC G YV+A C W+S N+
Sbjct: 381 LRSPFILGACLTTSIGIAIVLGSQVHGVRYFGVYILCM----GIYVNAACNCLWLSGNTG 436
Query: 444 SIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVLFAISIAGIPVFLFAKWYY 503
+ RA + + + S QI+ D P Y G ++ A + I + + + Y
Sbjct: 437 NYFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKGLSISLAFQVFSIFMTVVQIFLY 496
Query: 504 RTRNKRKEAIWSQMSE-DERVEYIQTTSDQ 532
+ N +K+AI + +E E + Y + SD+
Sbjct: 497 KRENDKKKAIIDRCNELGEPIPYDERLSDK 526
>SPCC757.13 [G] KOG2533 Permease of the major facilitator superfamily
Length = 522
Score = 118 bits (295), Expect = 3e-26
Identities = 103/467 (22%), Positives = 206/467 (44%), Gaps = 35/467 (7%)
Query: 86 VACFLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLISKRL 145
V C ++ LD+ LS A + D H+D + ++ LFY + +A+ P+ ++ ++
Sbjct: 80 VMCITYMIQYLDKTALSYAALYGMKTDTHIDGHTYSSMTTLFYAGYLVAQYPAAILMQKC 139
Query: 146 GPDIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTSKEL 205
FI + WS + AA N L R L G E + ++ +E
Sbjct: 140 RLSYFIFCNVFLWSAMVCLMAACRNGPSLLGLRFLAGIFEASITPAFINITAMWYRREEQ 199
Query: 206 SIRLSWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLSGFYLMV 265
+R ++ I Q++ ++L+YG+ + G +A W+Y+F++ G+++ +G ++ +
Sbjct: 200 PMRTLCWYAFNGIAQIIGSILSYGLGHIH--GKVASWRYVFIVIGLMS--LGWGVVFVFI 255
Query: 266 PGAVQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISDYDLWP 325
P ++ + RE++I + RV RD ++ + N+Q +K + A D +
Sbjct: 256 PSNPSKARFL------SSREKRIALERV-RD--NRTGLENKQ-FKWKHAYEAFLDPQVIM 305
Query: 326 IYLIGLIAYVPMNTVSTYLTLTLKSVGFSTLNVQLLSIPYQVIHITLLIGVTWYAERIDQ 385
I L + + N + + TL +K +G++ L+ +L++P I + + ++ ++ +
Sbjct: 306 ITLFTGVCMI-TNGIGVFSTLIIKGLGYNELHSAVLNMPLGAIEVAAMF-ISGVLCKVFK 363
Query: 386 RAYMGVIASIWNALFL-GVLRWWK-------GSLVEAWPTFALCTLLLGGPYVHAICVSW 437
+ +I N L L G L WK G LV W T + P A+ +S
Sbjct: 364 NGRL-LIGVFMNCLTLAGCLMIWKIPDSNPYGRLVGVWFTMWV-------PASSALLLSL 415
Query: 438 VSRNSNSIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVLFAISIAGIPVFL 497
+S N + ++SA + VG I S Q+++ P Y G + I +
Sbjct: 416 ISSNVAGYTKKTVTSATVFVFYSVGNIVSPQLFKSGQTPEYIEGIQAMIVSLCIIIAIAF 475
Query: 498 FAKWYYRTRNKRKEAIWSQ---MSEDERVEYIQTTSDQANKRLDFRF 541
YY NKR++ + ++ + E + E +D+ + +R+
Sbjct: 476 VLTGYYIYENKRRDRLLAEDPSLGESIKNEEFMDLTDRQQPKFRYRW 522
>SPBC1683.12 [G] KOG2533 Permease of the major facilitator superfamily
Length = 482
Score = 117 bits (293), Expect = 4e-26
Identities = 94/436 (21%), Positives = 190/436 (43%), Gaps = 18/436 (4%)
Query: 90 LFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLISKRLGPDI 149
L+ LDR N+ A L EDL + ++ +FY ++ AE PS L+ K+ GP
Sbjct: 51 LYFLSFLDRANIGNAAVVGLKEDLKLQAYQYSAAVSVFYATYITAETPSVLLVKKFGPHY 110
Query: 150 FIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTSKELSIRL 209
++ I WS+V + + + ++ R L+G EGGF L L+++ + +E RL
Sbjct: 111 YLSAMIIGWSLVTIFTCFVRHYWSLVLTRLLLGICEGGFFPCLSLYISMTYKREEQGKRL 170
Query: 210 SWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLSGFYLMVPGAV 269
++ + L+A G+ ++ GL W +L+++EG+++ + L +P
Sbjct: 171 AYLYVCSCFSGAFGGLIATGLTKIPKSSGLPNWGWLYIIEGLISAISAL-WILFCLPDDP 229
Query: 270 QTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISDYDLWPIYLI 329
T +++P RE++++ R + G + + A D ++ +I
Sbjct: 230 STARFLNP------REKELMKIRAEQRQKYMGSPN----FDWTQFRKAFKDPKMYMSCVI 279
Query: 330 GLIAYVPMNTVSTYLTLTLK-SVGFSTLNVQLLSIPYQVIHITLLIGVTWYAERIDQRAY 388
+ + +ST+L LK +G+S+L Q +S+P + + + ++R + R +
Sbjct: 280 QFCQDLVLYGISTFLPSILKLELGYSSLAAQYMSVPVYALGGISVYVICLLSDRTNIRGW 339
Query: 389 MGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYVHAICVSWVSRNSNSIKTR 448
+ + + +L S T+ + L P V A+ ++W++ N R
Sbjct: 340 FIIGMNFFGLAGFIILLATTNSAANYVATYLIALPLY--PTV-ALNITWINNNMAPHYRR 396
Query: 449 ALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVLFAISIAGIPVFLFAKWYYRTRNK 508
A + + + + Q+YR + Y G+ ++ G ++Y + +NK
Sbjct: 397 ATALGCNQTIGNLAGVIAGQVYRSSP---YKLGHGFALGCTVVGTLTATAMRFYLQRQNK 453
Query: 509 RKEAIWSQMSEDERVE 524
K+ I + DE+ E
Sbjct: 454 IKQEILNGERVDEKKE 469
>SPCC417.10 [G] KOG2533 Permease of the major facilitator superfamily
Length = 508
Score = 116 bits (291), Expect = 8e-26
Identities = 107/468 (22%), Positives = 206/468 (43%), Gaps = 41/468 (8%)
Query: 86 VACFLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLISKRL 145
V C ++ LD+ + S AV L EDL M+ ++ FYL + + E P+ L+ +R
Sbjct: 68 VMCLVYCIQFLDKTSNSYAVIMGLKEDLKMEGQMYSWSGTAFYLGYLVFEFPASLLLQRF 127
Query: 146 GPDIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTSKEL 205
+ + + W + + ++ N GF+ R L+G +E +L ++ E
Sbjct: 128 PLSKTLCVFLVIWGFL-LCMTSVANYPGFIALRVLLGMMESAASPGFILLTAQWYKRSEQ 186
Query: 206 SIRLSWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLSGFYLMV 265
+R S + + Q++ + +AYG+ + + + GW+ +F++ G+L + GF ++
Sbjct: 187 QLRTSVWVAFNGLGQILGSCMAYGLAKRTSL-PMRGWKLIFIICGVLAIFL---GFVIL- 241
Query: 266 PGAVQTKNWMHPKGWF-TEREEKIVVNRVLRDDPSKGDMHNRQPISFKL--LWSAISDYD 322
AV N K WF TE + K+VV R+ + G+ H FKL + D
Sbjct: 242 --AVVPDNPF--KAWFLTEEDRKLVVKRLRANKQGVGNNH------FKLYQFKETMLDIR 291
Query: 323 LWPIYLIGLIAYVPMNTVSTYLTLTLK-SVGFSTLNVQLLSIPYQVIHITLLIGVTWYAE 381
W +++ ++ +P + T+ +L +K ++G+ TL L+ +P LI + +
Sbjct: 292 TWIMFVSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAGACEFGGLIAFGFLSL 351
Query: 382 RIDQRAYMGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYVHAICVSWVSRN 441
I +R + I + AL L + G A LL+ P + + +S N
Sbjct: 352 FIHKRMVLATITTC-IALIGSCLLSFAG---PPRAQLAGYYLLMVSPGAMIVMFAIISSN 407
Query: 442 SNSIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVL---FAISIAGIPVFLF 498
++ + +Y + VG + Q ++ DAP Y + +A ++ P +
Sbjct: 408 ASGYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKNTMVGCYAATLVTFPALYY 467
Query: 499 AKWYYRTRNKRKEAIWSQMSEDERVEY-----IQTTSDQANKRLDFRF 541
W NKR++ Q++ + ++E+ + +D N LDFR+
Sbjct: 468 VNW---RENKRRD----QLAAEGKIEHRPNAEFEDLTDFEN--LDFRY 506
>SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator superfamily
Length = 552
Score = 113 bits (283), Expect = 6e-25
Identities = 97/461 (21%), Positives = 194/461 (42%), Gaps = 27/461 (5%)
Query: 81 FRVAFVACFLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQL 140
F V + L + L +D+ LS + L ED H+++N +N N LFY+ F + ++P +
Sbjct: 87 FTVLVMLMILDMMLYIDKATLSYSSILGLFEDTHINSNQYNDINTLFYVGFVIGQIPGHM 146
Query: 141 ISKRLGPDIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFF 200
+ +R F+ W+++ A +N +G + R +G +E + + + FF
Sbjct: 147 LLQRFPVSKFVAASTALWTIIIFLHCAAYNFSGLMALRFFLGLVESSLLPTMEATIGMFF 206
Query: 201 TSKELSIRLSWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLSG 260
E ++ +F+ S + + +AYG+ + ++ W+ ++ G +TF + + G
Sbjct: 207 PHSEQALLQPFFYISCYGCNIPAGFIAYGVQYAKNT--ISPWKLFMIIVGGITFFLTI-G 263
Query: 261 FYLMVPGAVQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISD 320
+ P T ++ T++E V+RV R + S + ++ ++++ A+ D
Sbjct: 264 LFFYYPDNTSTARFL------TKKERLYTVDRVRRSNHS--GIESKTFKKYQVI-EALKD 314
Query: 321 YDLWPIYLIGLIAYVPMNTVSTYLTLTLKSVGFSTLNVQLLSIPYQVIHITLLIGVTWYA 380
W ++ + N ++ L S+ S LN L+ + + I T+
Sbjct: 315 PVTW-LFTFHVFCNQLSNNLAYQQNLLFTSLNVSDLNSTLVGVASAGYNCVSAIIATYMM 373
Query: 381 ERI-DQRAYMGV---IASIWNALFLGVLRWWK--GSLVEAWPTFALCTLLLGGPYVHAIC 434
I +Q A+ G I SI + + W G L + G P++ I
Sbjct: 374 SVIKNQSAFHGAIWYIPSIAGGIACVAMSWDHKIGELAA-----IIIASNFGIPFI--IS 426
Query: 435 VSWVSRNSNSIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVLFAISIAGIP 494
+ W + + + ++ + + I Q+++ DAP Y+ V I+ + P
Sbjct: 427 LGWTTASCAGYTKKLTRGVMFMIGYAIANIIGPQMWQSRDAPRYYPAWIVQIVIAWSVSP 486
Query: 495 -VFLFAKWYYRTRNKRKEAIWSQMSEDERVEYIQTTSDQAN 534
V L +W RNK++ A+ Q E +I+T N
Sbjct: 487 FVLLIIRWILVRRNKKRLALLEQNKEQYEKTWIETIDSSGN 527
>YLR004c [G] KOG2533 Permease of the major facilitator superfamily
Length = 523
Score = 105 bits (262), Expect = 2e-22
Identities = 112/532 (21%), Positives = 205/532 (38%), Gaps = 42/532 (7%)
Query: 2 VDFEKQRVDSDVKRISLSSY-----DVELR--SQDSLD-SDNPFSDPLIAEYYRALYEES 53
+D EK+ ++D +S SS DV LR Q+ LD S D ++A EE+
Sbjct: 9 MDVEKKAANADSCSVSTSSINVDDADVALRFLKQNGLDESSTANEDDVVAG------EEA 62
Query: 54 KYESRSAFDPAFXXXXXXXXXXXXXXNFRVAFVACFLFIALQLDRGNLSQAVADNLLEDL 113
+ P F + F+ C ++ + LD+ L+ A + + +
Sbjct: 63 NFYGSHELSPKVLRKVDL---------FILPFLCC-TYLLMFLDKALLNYAASMGIKD-- 110
Query: 114 HMDTNDFNLGNQLFYLSFFLAELPSQLISKRLGPDIFIPIQICAWSVVAMAQAAMHNKAG 173
H+ N+F+ +F ++ E + ++ + I W +V AA A
Sbjct: 111 HLKGNEFSNLGTIFSAAYIFMEPVVTYLIQKFPISKILGTFITVWGIVLACHAACKTYAS 170
Query: 174 FLICRCLIGALEGGFIADLVLWLTYFFTSKELSIRLSWFWTSLSIVQVVSALLAYGILRM 233
++ R L+G E + ++T E S R+ ++ T +V L+++G L
Sbjct: 171 LMVVRTLLGLFESSSAVGCIAISGMYYTKSEQSARIGFWATQAGTGYIVGGLISFGFLHY 230
Query: 234 RGIGGLAGWQYLFLLEGILTFLIGLSGFYLMVPGAVQTKNWMHPKGWFTEREEKIVVNRV 293
G WQ +FL+ G++T G+ F L +P V WF +EEKI V
Sbjct: 231 HGT-AFTSWQIMFLVVGLVTVAFGVLTF-LYLPDNV-------TNAWFLNKEEKIQVVEH 281
Query: 294 LRDDPSKGDMHNRQPISFKLLWSAISDYDLWPIYLIGLIAYVPMNTVSTYLTLTLKSVGF 353
+R + + + + K L+ + D WP+ L+ + + + T+ + GF
Sbjct: 282 IRANQTGLETKKFKKQQVKELF--LHDKFTWPMLLLTACSQISTGAIGTFSVTITGTFGF 339
Query: 354 STLNVQLLSIPYQVIHITLLIGVTWYAERIDQRAYMGVIASIWNALFLGVLRWWKGSLVE 413
LL +P I +++ T R + S++ +G + L
Sbjct: 340 DKYETALLQLPIGAITAMIILITTQMLSRWGHITL--ITTSMYIPAIIGCIVLISLPLSH 397
Query: 414 AWPTFALCTLLLGGPYVHAICVSWVSRNSNSIKTRALSSALYNMAVQVGAIYSTQIYRKN 473
LL G V W S N++ R +A+ + V I + Q++R
Sbjct: 398 KIGNLFSLYLLYSGSCVITNIYIWNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAY 457
Query: 474 DAPLYHTGNTVLFAISIAGIPVFLFAKWYYRTRNKRKEAIWSQMSEDERVEY 525
AP Y L +P+ L+ + + N++++ + ER +Y
Sbjct: 458 SAPRYIPAKIALLVTQCVCVPLQLYIGYICKKENEKRD---KEQEGQERKKY 506
>SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator superfamily
Length = 570
Score = 102 bits (255), Expect = 1e-21
Identities = 90/448 (20%), Positives = 188/448 (41%), Gaps = 27/448 (6%)
Query: 89 FLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLISKRLGPD 148
FL + L + + LS + L +D+H+ +N +N N LFY+ + + + P I +
Sbjct: 108 FLDMMLFIGKATLSYSTILGLFDDVHITSNQYNNLNTLFYVGYIVGQFPGHYIMQTFPLG 167
Query: 149 IFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTSKELSIR 208
F+ + +WSV+ +N G + R +G E + + + FFT +E +
Sbjct: 168 KFVGLVTFSWSVIVFLHCCAYNYGGLIALRFFLGFTESCLLPAMEATMGMFFTHQEQAFL 227
Query: 209 LSWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLSGFYLMVPGA 268
FW S + + +AYG+ + +A W+ ++ G +TF + + F+
Sbjct: 228 QPVFWISCLSCGIPAGFIAYGLEFV--TKSIAPWKLFMIITGGITFFLSIFLFFYYPDNP 285
Query: 269 VQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISDYDLWPIYL 328
+ + + T+ E+ ++RV + ++G + N+ + + A+ D W ++
Sbjct: 286 SKAR-------FLTDEEKLYTIDRVRKS--TRGGIENKIFKKHQFI-EALKDPITW-LFT 334
Query: 329 IGLIAYVPMNTVSTYLTLTLKSVGFSTLNVQLLSIPYQVIHITLLIGVTWYAERI-DQRA 387
+ N ++ L S+ S LN L+ + + I T+ I +Q A
Sbjct: 335 FAAFTLMLSNNLAYQQNLIFTSLNVSDLNSTLVGVALAGYNTVSAIIATFAMYLIPNQSA 394
Query: 388 Y---MGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPY--VHAICVSWVSRNS 442
Y ++ SI + L W + E L T+++ + + I + W + S
Sbjct: 395 YHAMFWMLPSITGGIAFVALP-WSNRIGE------LATMIIASDFGITYIIALGWTTATS 447
Query: 443 NSIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVLFAISIAGIP-VFLFAKW 501
+ ++ + + I S Q+++ DAP Y+ V ++ P ++L A+
Sbjct: 448 TGYTKKLTRGLMFMVGYAIANIISPQLWQSRDAPRYYPAWIVQIVVAWFVTPIIYLVARV 507
Query: 502 YYRTRNKRKEAIWSQMSEDERVEYIQTT 529
RNK+++ + + + +E I+ T
Sbjct: 508 ILARRNKQRKELKDKKIAEGSLETIEKT 535
>SPBC1773.15 [G] KOG2533 Permease of the major facilitator superfamily
Length = 497
Score = 100 bits (250), Expect = 4e-21
Identities = 91/448 (20%), Positives = 195/448 (43%), Gaps = 35/448 (7%)
Query: 88 CFLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLISKRLGP 147
C + +D+ + + + DL+M N +N FYL F + LP + ++
Sbjct: 57 CLISAFQYMDKSTSNYSSIMGIRTDLNMVGNQYNWVGTSFYLGFMVFSLPLSTLLQKFPL 116
Query: 148 DIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTSKELSI 207
I AW ++ +H+ A ++ R L+G LE VL++ ++ +E
Sbjct: 117 SKVTSAFIVAWGILMTLTCLVHSYASYIATRTLLGILESVITPAFVLFIAQWYRKEEQFF 176
Query: 208 RLSWFWTSLSIVQVVSALLAYGILRMRGIGGL--AGWQYLFLLEGILTFLIGLSGFYLMV 265
R+++ + ++ ++YG+ + L + W+ LF++ G++T + G+ ++ +
Sbjct: 177 RMAFLVAWNGLGGLIGGSMSYGLYKRELENNLTMSPWRILFIITGLITIINGVF-IFIHI 235
Query: 266 PGAVQTKNWMHPKGWF-TEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISDYDLW 324
P K WF +E+E+ +V+ R+ D G ++ +++L A D ++
Sbjct: 236 PDEPS-------KAWFLSEKEKDLVLKRLDTDHAGLGSKKFKK---YQIL-EACRDVRMY 284
Query: 325 PIYLIGLIAYVPMNTVSTYLTLTLKSVGFSTLNVQLLSIPYQVIH---ITLLIGVTWYAE 381
+ + + +P +S + ++ LK++G+ L+++P I +TL + +
Sbjct: 285 LYFFLQIAVAIPNGGLSNFSSIMLKNLGYVKGKALLMNMPTSSISFAALTLFGLIPEFTN 344
Query: 382 RIDQRAYMGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYVHAICV-SWVSR 440
R A +G+ ++ + + + L W L G + IC+ S +S
Sbjct: 345 RRMDIALVGLAINLTSGSLIAFAKPTHAQLAGYW--------LFGISPIPYICILSCISS 396
Query: 441 NSNSIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVLFAISIAGIPVFLFAK 500
NS + SA+ + VG + Q +R AP Y G V F + + +F+
Sbjct: 397 NSAGHTKKVFMSAVSMIGYCVGNMVGPQTFRSTQAPKYQ-GAKVSFVVCYC-VAIFIIIA 454
Query: 501 WY------YRTRNKRKEAIWSQMSEDER 522
Y R R+++ E + +++SE+++
Sbjct: 455 IYAVNVRENRRRDEKNEYLSNELSEEDK 482
>YAL067c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 94.7 bits (234), Expect = 3e-19
Identities = 95/438 (21%), Positives = 186/438 (41%), Gaps = 22/438 (5%)
Query: 83 VAFVACFLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLIS 142
+AF +C + LD N++ A + EDL ND ++ + + +LP +
Sbjct: 139 LAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVMYTVGNIIFQLPFLIYL 198
Query: 143 KRLGPDIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTS 202
+L + +P WS++ + A +++ R IGA E F+
Sbjct: 199 NKLPLNYVLPSLDLCWSLLTVGAAYVNSVPHLKAIRFFIGAFEAPSYLAYQYLFGSFYKH 258
Query: 203 KELSIRLSWFWTSLSIVQVVSALLAYGI-----LRMRGIGGLAGWQYLFLLEGILTFLIG 257
E+ R ++++ + Q + L A GI + G+ GL GW++ F+++ I++ ++G
Sbjct: 259 DEMVRRSAFYY----LGQYIGILSAGGIQSAVYSSLNGVNGLEGWRWNFIIDAIVSVVVG 314
Query: 258 LSGFYLMVPGAVQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSA 317
L GFY +PG + + T+ E ++ R+ + K D + KL +
Sbjct: 315 LIGFY-SLPGDPYNCYSI----FLTDDEIRLARKRLKENQTGKSDFETK-VFDIKLWKTI 368
Query: 318 ISDYDLWPIYLIGLIAYVPMNTVSTYLTLTLKSV-GFSTLNVQLLSIPYQVIHITLLIGV 376
SD+ ++ + L + + N S L LKS+ +S + LS+ + + L+
Sbjct: 369 FSDWKIYILTLWNIFCWNDSNVSSGAYLLWLKSLKRYSIPKLNQLSMITPGLGMVYLMLT 428
Query: 377 TWYAERIDQRAYMGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYVHAICVS 436
A+++ R + + ++N + +L W + W F L G + + S
Sbjct: 429 GIIADKLHSRWFAIIFTQVFNIIGNSILAAWDVAEGAKWFAFMLQCF---GWAMAPVLYS 485
Query: 437 WVSR-NSNSIKTRALSSALYNMAVQVGAIY-STQIYRKNDAPLYHTGNTVLFAISIAGIP 494
W + +TRA++ N+ Q + S +++ +AP Y G T A S +
Sbjct: 486 WQNDICRRDAQTRAITLVTMNIMAQSSTAWISVLVWKTEEAPRYLKGFT-FTACSAFCLS 544
Query: 495 VFLFAKWYYRTRNKRKEA 512
++ F Y+ R++R A
Sbjct: 545 IWTFVVLYFYKRDERNNA 562
>YLL055w [G] KOG2533 Permease of the major facilitator superfamily
Length = 531
Score = 89.7 bits (221), Expect = 1e-17
Identities = 92/461 (19%), Positives = 191/461 (40%), Gaps = 31/461 (6%)
Query: 82 RVAFVACFLFIA-----LQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAEL 136
R F+ F F++ L +D+ LS ED + N +N N LFY+ F + +
Sbjct: 53 RKLFLTIFTFVSAINLLLYMDKATLSYDSILGFFEDTGLTQNTYNTVNTLFYVGFAIGQF 112
Query: 137 PSQLISKRLGPDIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWL 196
P Q ++++L F+ + W+++ +N +G + R +G E I L+ +
Sbjct: 113 PGQYLAQKLPLGKFLGGLLATWTILIFLSCTAYNFSGVVALRFFLGLTESVVIPILITTM 172
Query: 197 TYFFTSKELSIRLSWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLI 256
FF + E + +F+ + + + +AYG+L + ++ W+ ++ G LTF++
Sbjct: 173 GMFFDASERAAAQPFFFAACMGSPIPTGFIAYGVLHITN-PSISLWKIFTIIIGGLTFIM 231
Query: 257 GLSGFYLMVPGAVQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWS 316
+ K +F+ +E ++ RV S G ++
Sbjct: 232 TVVVILWFPNNPADVK-------FFSIQERVWIIRRV---QASTGSSIEQKVFKKSQFRE 281
Query: 317 AISDYDLWPIYLIGLIAYVPMNTVSTYLTLTLKSVGFSTLNVQLLSIP---YQVI--HIT 371
A+ DY W L L+ + N L G L L+S+ + V+ I
Sbjct: 282 AMKDYITWLFGLFFLLQQLANNLPYQQNLLFEGMGGVDALGSTLVSVAGAGFAVVCAFIA 341
Query: 372 LLIGVTWYAERIDQ-RAYMGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYV 430
L+ W + I A + ++ ++ L W + + + + G P++
Sbjct: 342 TLMLAKW--KNISALTAIFWTLPALVGSIAAAALPW--DNKIGILANICMAGQIFGIPFI 397
Query: 431 HAICVSWVSRNSNSIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTVLFAISI 490
I +SW S +++ + S++ A+ + I S QI+R+ D+P + V +S
Sbjct: 398 --IALSWASSSASGYTKKLTRSSVSLFAMGIANIISPQIWREKDSPRFLPAWIVQIVLSF 455
Query: 491 AGIP-VFLFAKWYYRTRNKRKEAIWSQMSED--ERVEYIQT 528
+ P + L + + RN ++ + + ++ +R++ I++
Sbjct: 456 SLAPAILLLIHFILKRRNNQRLKNYDENLQNYLDRIQLIES 496
>YJR152w [G] KOG2533 Permease of the major facilitator superfamily
Length = 543
Score = 88.2 bits (217), Expect = 3e-17
Identities = 102/484 (21%), Positives = 200/484 (41%), Gaps = 62/484 (12%)
Query: 88 CFLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAEL-PSQLISKRLG 146
C L+ +D+ + S A L DL M + ++ FY + L P Q I +R
Sbjct: 90 CILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWVTSAFYFGYLFMNLGPVQFIFQRTS 149
Query: 147 P-DIFIPIQICAWSVVAMAQAAMHNK-AGFLICRCLIGALEGGFIADLVLWLTYFFTSKE 204
+ + I W ++ AA K F++ R L+G E + ++ ++E
Sbjct: 150 HMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAESVVTPCFTIITAQYWKTEE 209
Query: 205 LSIRLSWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLSGFYLM 264
R+S ++ + ++ +AYG+ + + GW+ LF++ G++T IG+ +L
Sbjct: 210 QFTRVSIWFGMNGLGSILINAIAYGVYIHQDSYAIKGWRTLFVITGVITIFIGIL-IFLW 268
Query: 265 VPGAVQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISDYDLW 324
+P ++ ++RE+ +VV R+ + G N + ++++ A+ D W
Sbjct: 269 IPDDPSKARFL------SKREKLMVVQRIRSNQQGFG---NHEIKKYQII-EALKDVRTW 318
Query: 325 PIYLIGLIAYVPMNTVSTYLTLTLKS-VGFSTLNVQLLSIPYQVIHITLLIGVTWYAERI 383
+L + + +P +S+++++ L S G+S+ L+ +P + L+G +
Sbjct: 319 LYFLFTVSSNIPNGGISSFMSILLNSDFGYSSKETLLMGLPTGAVE---LVGCPLFG--- 372
Query: 384 DQRAYMGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLL----------------LGG 427
I +++ A + +WK L +W FA L L G
Sbjct: 373 --------ILAVYAA--NKKIPFWKYKL--SWAIFAAVLALIASCMLGFATNSKKARLAG 420
Query: 428 PY------VHAICV-SWVSRNSNSIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLYH- 479
Y V ICV S +S NS+ + S++ +A + Q + AP YH
Sbjct: 421 AYLWYISPVSFICVLSNISANSSGYSKKWTVSSINLVAYAAANLAGPQTFIAKQAPKYHG 480
Query: 480 --TGNTVLFAISIAGIPVFLFAKWYYRTRNKRKEAIWSQMSEDERVEYIQTTSDQANKRL 537
V +A+ I + + L NKR++ I ++ E E ++ + +
Sbjct: 481 AKVAMVVCYAVMIVLLSILLIVN---LRENKRRDKIAAERGFPEETENLEFSDLTDFENP 537
Query: 538 DFRF 541
+FR+
Sbjct: 538 NFRY 541
>YGR065c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 82.0 bits (201), Expect = 2e-15
Identities = 97/437 (22%), Positives = 183/437 (41%), Gaps = 17/437 (3%)
Query: 86 VACFLFI---ALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLIS 142
+A + F+ + +D N + A N+ EDL+M ND+ + + + + +LP +
Sbjct: 129 IALYFFMLCWSKSVDLNNYTNAYVSNMKEDLNMKGNDYVYTSTIANVGAIVFQLPFMYLL 188
Query: 143 KRLGPDIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTS 202
R I +P+ W+ A ++ A R ++ A + L ++
Sbjct: 189 PRFPSHIILPVMDLGWTWFTFACYRANSLAELRAYRFILSAFGAAYYPVSQYILGCWYAP 248
Query: 203 KELSIRLSWFWTSLSIVQVVSALLAYGILR-MRGIGGLAGWQYLFLLEGI-LTFLIGLSG 260
E++ R+ F+ + V S LL I + + G+ GLAGW+++FL++ I ++ + G
Sbjct: 249 DEINSRVCLFFCGQQLGSVTSGLLQSRIFKSLNGVHGLAGWRWMFLIDAIAISLPTAIIG 308
Query: 261 FYLMVPGAVQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKG-DMHNRQPISFKLLWSAI- 318
F+ ++PG V +K + + T+ E +I R R+ G D P+ + LW +
Sbjct: 309 FF-VIPG-VPSKCY---SLFLTDEEIRIARARNKRNQIKDGVDKSKLAPLWSRKLWKKVF 363
Query: 319 SDYDLWPIYLIGLIAYVPMNTVSTYLTLTLKS-VGFSTLNVQLLSIPYQVIHITLLIGVT 377
W + + ++ M S TL LKS +S V LS+ + +I
Sbjct: 364 CTPAFWVLVVFDTCSWNNMTAYSGSYTLWLKSNTKYSIAQVNNLSVIPACLGFAYVIFCA 423
Query: 378 WYAERIDQRAYMGVIASIWNALFLGVLRWWKGSLVEAWPTFALCTLLLGGPYVHAICVSW 437
+ A+ + V A+I N + +L W W F + ++
Sbjct: 424 FGADLFRCKWIFMVFAAIMNTVSCALLIKWDIPSKAKWYAFFTTYFSVAASPCLWSFIND 483
Query: 438 VSRNSNSIKTRALSSALYNMAVQVGAIYSTQIYRKNDAPLYHTGNTV-LFAISIAGIPVF 496
R +K A+Y+ + A T + ++P + TG TV L +I G+ +
Sbjct: 484 FLRFDPQVKA-ITWIAIYSFSQSTYAWIPTLAWPTVESPRFKTGYTVSLIFGAIYGL--W 540
Query: 497 LFAKWYYRTRNKRKEAI 513
F ++ RN++K A+
Sbjct: 541 TFVVLFFYKRNEKKHAL 557
>SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superfamily
Length = 514
Score = 80.1 bits (196), Expect = 8e-15
Identities = 54/247 (21%), Positives = 113/247 (44%), Gaps = 13/247 (5%)
Query: 88 CFLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQLISKRLGP 147
C + LDR +++ A + EDL M N+ N +F + + +LP +R+
Sbjct: 37 CVSYFINYLDRSSINNAYLSGMQEDLKMHGNELQDINVVFTCGYIIGQLPGSYALQRVPA 96
Query: 148 DIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFFTSKELSI 207
++ + W ++ + A+H+ +I R + E A L ++ EL
Sbjct: 97 RLWFSVMNILWGLMTIFSFAVHSVRALMILRFFMAVAEASTFAGTHYILGAWYKESELCK 156
Query: 208 RLSWFWTSLSIVQVVSALLAYGI-LRMRGIGGLAGWQYLFLLEGILTFLIGLSGFYLMVP 266
R F S + + + L + + G GGL+GW++LF+++GILT + L G +L
Sbjct: 157 RAGIFSASGLVGTMFAGYLQTAVHSSLNGKGGLSGWRWLFIIDGILTIPLSLYGLFLFPD 216
Query: 267 GAVQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNRQPISFKLLWSAISDYDLWPI 326
TK +FTE+E+++ R+ P++ ++P++ K + + + ++ +
Sbjct: 217 VPETTK-----APYFTEQEKELSFKRL----PAR---PKKKPLTLKAIKDIVRSWRIYGL 264
Query: 327 YLIGLIA 333
++ + +
Sbjct: 265 CILWIFS 271
>SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 568
Score = 79.0 bits (193), Expect = 2e-14
Identities = 67/296 (22%), Positives = 133/296 (44%), Gaps = 17/296 (5%)
Query: 85 FVACFLFIALQLDRGNLSQAVADNLLEDLH-MDTNDFNLGNQLFYLSFFLAELPSQLISK 143
F++C L + L ++ A +L++ L + LG LFY+ + + E+PS L+
Sbjct: 94 FLSCCLRFTVSLSF-TMNTAQGHSLIQTLSGYSAHYLALGLALFYVGYIIFEVPSNLMMA 152
Query: 144 RLGPDIFIPIQICAWSVVAMAQAAMHNKAG----FLICRCLIGALEGGFIADLVLWLTYF 199
+ P I++ VV A + K G ++ R +G E G L +++ +
Sbjct: 153 FIEPRIWVSRIQLTIGVVGACHAVLGTKHGNAQSYVALRFFLGVAESGLWPGLAYYMSRW 212
Query: 200 FTSKELSIRLSWFWTSLSIVQVVSALLAYGILRMRGIGGLAGWQYLFLLEGILTFLIGLS 259
+ K L R+ W++T+ I +L++ G +M G GL G+Q++FL+ G++ LS
Sbjct: 213 YRGKHLGKRIGWYYTAAQIAAAAVSLVSAGFQKMDGARGLYGYQWMFLIWGVVAIAQALS 272
Query: 260 -GFYLMVPGAVQTKNWMHPKGWFTEREEKIVVNRVLRDDPSKGDMHNR----QPISFKLL 314
++L + + + + + + + R+ P+ +H+R + +
Sbjct: 273 IPWWLPAVASKEHRKSLSSFIPLPKWMKTLSPQRIGFLTPADKSLHSRYIAEMNVGKRWQ 332
Query: 315 WS----AISDYDLWPIYLIGLIAYVPMNTVSTYLTLTLKSV--GFSTLNVQLLSIP 364
WS + D +WP L+ N + Y TL ++ + FS +++ LL+ P
Sbjct: 333 WSDLLKSCLDLRVWPFILMYFGIVGVGNGIFNYCTLIIEEINPSFSGIDISLLNAP 388
>SPAC1B3.15c [G] KOG2533 Permease of the major facilitator superfamily
Length = 628
Score = 71.6 bits (174), Expect = 3e-12
Identities = 38/148 (25%), Positives = 74/148 (49%), Gaps = 4/148 (2%)
Query: 115 MDTNDFNLGNQLFYLSFFLAELPSQLISKRLGPDIFIPIQICAWSVVAMAQAAMHNK--- 171
++ + ++G L Y+S + +LPS L+ R P +++ ++ A + K
Sbjct: 196 LNYHTLSVGTGLSYVSLIIFDLPSNLLMTRADPRLWLSRIQVTTGIIGACHAVLGTKGSS 255
Query: 172 -AGFLICRCLIGALEGGFIADLVLWLTYFFTSKELSIRLSWFWTSLSIVQVVSALLAYGI 230
+GF+ R G G + + F+ + L R+ W++T+ I V ++LL+
Sbjct: 256 ASGFIALRFFNGLAIAGMWPGFAFYTSRFYRDQHLGKRIGWYYTAAQISSVATSLLSAAF 315
Query: 231 LRMRGIGGLAGWQYLFLLEGILTFLIGL 258
+M G+ GL G+Q++FL+ G++ F GL
Sbjct: 316 QKMDGLHGLYGYQWMFLIWGVVAFTQGL 343
>YCR028c [G] KOG2533 Permease of the major facilitator superfamily
Length = 512
Score = 63.2 bits (152), Expect = 1e-09
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 3/188 (1%)
Query: 81 FRVAFVACFLFIALQLDRGNLSQAVADNLLEDLHMDTNDFNLGNQLFYLSFFLAELPSQL 140
F ++FV C + +DR + A + EDL M ND + N +F + + + +P+ L
Sbjct: 36 FVLSFV-CLQYWINYVDRVGFTNAYISGMKEDLKMVGNDLTVSNTVFMIGYIVGMVPNNL 94
Query: 141 ISKRLGPDIFIPIQICAWSVVAMAQAAMHNKAGFLICRCLIGALEGGFIADLVLWLTYFF 200
+ + P I++ AW ++ + + + R E + L ++
Sbjct: 95 MLLCVPPRIWLSFCTFAWGLLTLGMYKVTSFKHICAIRFFQALFESCTFSGTHFVLGSWY 154
Query: 201 TSKELSIRLSWFWTSLSIVQVVSALLAYGIL-RMRGIGGLAGWQYLFLLEGILTFLIGLS 259
EL IR + F S + + S + I + G GLAGW++LF+++ +T I +
Sbjct: 155 KEDELPIRSAIFTGSGLVGSMFSGFMQTSIFTHLNGRNGLAGWRWLFIIDFCITLPIAIY 214
Query: 260 GFYLMVPG 267
GF + PG
Sbjct: 215 GF-IFFPG 221
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.139 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,479,703
Number of Sequences: 60738
Number of extensions: 1238545
Number of successful extensions: 3659
Number of sequences better than 1.0e-05: 22
Number of HSP's better than 0.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 3601
Number of HSP's gapped (non-prelim): 24
length of query: 543
length of database: 30,389,216
effective HSP length: 111
effective length of query: 432
effective length of database: 23,647,298
effective search space: 10215632736
effective search space used: 10215632736
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)