ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2651 check: MH L KOG0480 Replication, recombination and repair DNA replication licensing factor, MCM6 component
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2651 938629 935621 -1003
(1003 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL201c [L] KOG0480 DNA replication licensing factor MCM6 component 1234 0.0
SPBC211.04c [L] KOG0480 DNA replication licensing factor MCM6 co... 862 0.0
Hs7427519 [L] KOG0480 DNA replication licensing factor MCM6 comp... 635 0.0
CE00415 [L] KOG0480 DNA replication licensing factor MCM6 component 615 e-175
7290738 [L] KOG0480 DNA replication licensing factor MCM6 component 597 e-170
ECU05g0780 [L] KOG0480 DNA replication licensing factor MCM6 com... 514 e-145
SPBC25D12.03c [L] KOG0482 DNA replication licensing factor MCM7 ... 355 3e-97
7295030 [L] KOG0482 DNA replication licensing factor MCM7 component 347 7e-95
At2g16440 [L] KOG0478 DNA replication licensing factor MCM4 comp... 342 1e-93
YPR019w [L] KOG0478 DNA replication licensing factor MCM4 component 338 3e-92
Hs21359886 [L] KOG0482 DNA replication licensing factor MCM7 com... 337 4e-92
YBR202w [L] KOG0482 DNA replication licensing factor MCM7 component 336 1e-91
At4g02060 [L] KOG0482 DNA replication licensing factor MCM7 comp... 330 5e-90
CE21767 [L] KOG0478 DNA replication licensing factor MCM4 component 327 4e-89
Hs14738665 [L] KOG0478 DNA replication licensing factor MCM4 com... 322 2e-87
7304207 [L] KOG0478 DNA replication licensing factor MCM4 component 316 1e-85
ECU02g1150 [L] KOG0478 DNA replication licensing factor MCM4 com... 311 2e-84
Hs6631095 [L] KOG0479 DNA replication licensing factor MCM3 comp... 303 7e-82
HsM14149623 [L] KOG0482 DNA replication licensing factor MCM7 co... 297 5e-80
CE09874 [L] KOG0482 DNA replication licensing factor MCM7 component 296 1e-79
YLR274w [L] KOG0481 DNA replication licensing factor MCM5 component 295 2e-79
Hs19923727 [L] KOG0480 DNA replication licensing factor MCM6 com... 295 3e-79
7299365 [L] KOG0481 DNA replication licensing factor MCM5 component 290 8e-78
Hs11418031 [L] KOG0481 DNA replication licensing factor MCM5 com... 288 3e-77
At3g09660 [L] KOG0480 DNA replication licensing factor MCM6 comp... 288 3e-77
Hs6981192 [L] KOG0481 DNA replication licensing factor MCM5 comp... 285 2e-76
SPAC3F10.01 [L] KOG0481 DNA replication licensing factor MCM5 co... 284 6e-76
At2g07690 [L] KOG0481 DNA replication licensing factor MCM5 comp... 283 1e-75
7290573 [L] KOG0479 DNA replication licensing factor MCM3 component 281 5e-75
CE19038 [L] KOG0477 DNA replication licensing factor MCM2 component 280 1e-74
YEL032w [L] KOG0479 DNA replication licensing factor MCM3 component 277 5e-74
SPCC1682.02c [L] KOG0479 DNA replication licensing factor MCM3 c... 277 5e-74
SPBC4.04c [L] KOG0477 DNA replication licensing factor MCM2 comp... 276 1e-73
CE03558 [L] KOG0481 DNA replication licensing factor MCM5 component 274 6e-73
At5g46280 [L] KOG0479 DNA replication licensing factor MCM3 comp... 271 5e-72
7299005 [L] KOG0477 DNA replication licensing factor MCM2 component 268 2e-71
ECU06g0340 [L] KOG0481 DNA replication licensing factor MCM5 com... 263 1e-69
Hs20535929 [L] KOG0477 DNA replication licensing factor MCM2 com... 262 2e-69
CE08392 [L] KOG0479 DNA replication licensing factor MCM3 component 261 3e-69
ECU08g0290 [L] KOG0479 DNA replication licensing factor MCM3 com... 256 2e-67
At1g44900 [L] KOG0477 DNA replication licensing factor MCM2 comp... 251 4e-66
YBL023c [L] KOG0477 DNA replication licensing factor MCM2 component 248 4e-65
ECU04g0850 [L] KOG0477 DNA replication licensing factor MCM2 com... 245 3e-64
Hs4758706 [L] KOG0477 DNA replication licensing factor MCM2 comp... 242 2e-63
ECU09g1360 [L] KOG0482 DNA replication licensing factor MCM7 com... 234 7e-61
ECU11g0800 [L] KOG0480 DNA replication licensing factor MCM6 com... 186 2e-46
ECU07g0490 [L] KOG0478 DNA replication licensing factor MCM4 com... 162 3e-39
At2g14050 [L] KOG0477 DNA replication licensing factor MCM2 comp... 144 5e-34
SPCC16A11.17 [L] KOG0478 DNA replication licensing factor MCM4 c... 112 3e-24
7300061 [L] KOG0478 DNA replication licensing factor MCM4 component 109 2e-23
Hs22056246 [L] KOG0477 DNA replication licensing factor MCM2 com... 74 1e-12
>YGL201c [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 1017
Score = 1234 bits (3194), Expect = 0.0
Identities = 646/1003 (64%), Positives = 759/1003 (75%), Gaps = 38/1003 (3%)
Query: 21 VGA-YDSSQFDDQSLGNRTPQFPSSSRGVSDGNRHFGTDDTRQGINSESQIEAME----- 74
+GA + SS D +G+R FPSSS+ H T +N +Q +
Sbjct: 25 IGAGFGSSSGLDSQIGSRL-HFPSSSQP------HVSNSQTGPFVNDSTQFSSQRLQTDG 77
Query: 75 ---NDSQEITPLAGIRQKNLNAIKKVDDKTGETVREAFEHFLSNFTALNDETGEMEKVYR 131
ND + P + + LN +KKVDD TGE VREAFE FL +F+ + +TGE+EKVYR
Sbjct: 78 SATNDMEGNEPARSFKSRALNHVKKVDDVTGEKVREAFEQFLEDFSVQSTDTGEVEKVYR 137
Query: 132 VQIEYMRWYELNTIYVDYKHLAEVEDGALAVAILQQYYRFLPFLLSGLRNVVKKYAPGLL 191
QIE+M+ Y+LNTIY+DY+HL+ E+GALA+AI +QYYRFL FL GLR VV+KYAP LL
Sbjct: 138 AQIEFMKIYDLNTIYIDYQHLSMRENGALAMAISEQYYRFLAFLQKGLRRVVRKYAPELL 197
Query: 192 LTSDSVLPSQSQENXXXXXXXXXX----XXLPT---SQAATAGGTAPS-----TIATNPD 239
TSDS+ S+ E LP S AA GT+ T +T+P+
Sbjct: 198 NTSDSLKRSEGDEGQADEDEQQDDDMNGSSLPRDSGSSAAPGNGTSAMATRSITTSTSPE 257
Query: 240 QVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAV 299
Q ERV QISF NLPTVHRIRDIR+ KIGSL++ISGTVTRTSE+RPELYKASFTC++CRA+
Sbjct: 258 QTERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAI 317
Query: 300 IDNVEQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTL 359
+DNVEQ FKYTEPT CPNP+CEN++FW+LNV RS+FLDWQKVRIQEN+NEIP+GSMPRTL
Sbjct: 318 VDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTL 377
Query: 360 DIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGI 419
D+ILRGD VERAKPGDRCKF G EIVVPDV+QLGLPGVK SST D+RGIS+TTEGLNSG+
Sbjct: 378 DVILRGDSVERAKPGDRCKFTGVEIVVPDVTQLGLPGVKPSSTLDTRGISKTTEGLNSGV 437
Query: 420 SGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAA 479
+GL+SLGVRDLTYKISFLACHV ++G++ S + ++ ++ N
Sbjct: 438 TGLRSLGVRDLTYKISFLACHVISIGSNIGASSPDANSNNRETELQMAANLQANNVYQDN 497
Query: 480 ETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHK 539
E DQE+FL L SDEINELKEMVKDE+IYDKLV+SIAPAVFGHE +KKGILLQML GVHK
Sbjct: 498 ERDQEVFLNSLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHK 557
Query: 540 TTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEE 599
+TVEGIKLRGDINIC+VGDPSTSKSQFLKYV F+PR+VYTSGKASSAAGLTAAVV+DEE
Sbjct: 558 STVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEE 617
Query: 600 GGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTS 659
GGD+TIEAGALMLADNG+CCIDEFDKMDI+DQVAIHEAMEQQTISIAKAGIHATLNARTS
Sbjct: 618 GGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTS 677
Query: 660 ILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMK 719
ILAAANPVGGRYNRKL+LR NLNM+APIMSRFDLFFVILDDCNEKIDTELASHIVDLHMK
Sbjct: 678 ILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMK 737
Query: 720 RDSAINPPFSAEQLSRYINYAKTFKPVMTKEARDYLVKRYTELRKDDAQGYSKSSYRITV 779
RD AI PPFSAEQL RYI YA+TFKP++TKEAR YLV++Y ELRKDDAQG+S+SSYRITV
Sbjct: 738 RDEAIEPPFSAEQLRRYIKYARTFKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITV 797
Query: 780 RQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQSXXXXXXXXXXXXXXXNSPE-EST 838
RQLES+IRLSEAIARANCVDEI PSF+AEAYDLLRQS ++ E +S
Sbjct: 798 RQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRVDVDDVEMDEEFDNIESQSH 857
Query: 839 EGEGTIPATQHFGETLDTQSQSPSQPLNADSETGGGPDVESHDNAHHTTHKVAISYDKYV 898
G + S+ P+ SE P K ++YDKYV
Sbjct: 858 AASGNNDDNDDGTGSGVITSEPPADIEEGQSEATARPGTSE-------KKKTTVTYDKYV 910
Query: 899 EMMNLIVRKVVDREKNEEPEMTKTEIVDWYLQQKENDINTEAEYWQERKLAFKVIKRLVK 958
MMN+IVRK+ + ++ E+T +IVDWYL QKEND+ + AEYW+ER+LAFKVIKRLVK
Sbjct: 911 SMMNMIVRKIAEVDREGAEELTAVDIVDWYLLQKENDLGSLAEYWEERRLAFKVIKRLVK 970
Query: 959 DRVLMQIHGQNDDLS--ADVESSNAKTVYVIHPNCSVLDEITP 999
DR+LM+IHG +L + E+ N KTVYVIHPNC VLD++ P
Sbjct: 971 DRILMEIHGTRHNLRDLENEENENNKTVYVIHPNCEVLDQLEP 1013
>SPBC211.04c [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 892
Score = 862 bits (2227), Expect = 0.0
Identities = 487/938 (51%), Positives = 609/938 (64%), Gaps = 101/938 (10%)
Query: 66 SESQIEAMENDSQEIT--PLAGIRQKNLNAIKKVDDKTGETVREAFEHFLSNFTALNDET 123
S+ + AM D + P A I + AI KV D TGE+VREAFE FL +F+
Sbjct: 35 SQPESSAMLEDDGMVKRKPFAAIGE----AIPKVIDTTGESVREAFEEFLLSFSDDRVAG 90
Query: 124 GE------MEKVYRVQIEYMRWYELNTIYVDYKHLAEVEDGALAVAILQQYYRFLPFLLS 177
G+ EK Y QI + YE++T+YVDYKHL D LA+AI++QYYRF PFLL
Sbjct: 91 GDALPSASQEKYYVQQIHGLAMYEIHTVYVDYKHLTSYND-VLALAIVEQYYRFSPFLLR 149
Query: 178 GLRNVVKKYAPGLLLTSDSVLPSQSQENXXXXXXXXXXXXLPTSQAATAGGTAPSTIATN 237
L+ +++K+ P + S S+EN ++++ N
Sbjct: 150 ALQKLIEKFEP------EYYRSSLSREN--------------------------ASLSPN 177
Query: 238 PDQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCR 297
++ ++F NLP IRD+R ++IG L I+GTVTRTSE+RPEL + +F CE C
Sbjct: 178 FKASDKTFALAFYNLPFRSTIRDLRTDRIGRLTTITGTVTRTSEVRPELAQGTFICEECH 237
Query: 298 AVIDNVEQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPR 357
V+ NVEQ F+YTEPT CPN C N+ W LN+++S F DWQKVRIQENSNEIP+GSMPR
Sbjct: 238 TVVSNVEQAFRYTEPTQCPNELCANKRSWRLNISQSSFQDWQKVRIQENSNEIPTGSMPR 297
Query: 358 TLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNS 417
TLD+ILRGD VERAK GD+C F G I VPDVSQLG+PGVK + DSR
Sbjct: 298 TLDVILRGDIVERAKAGDKCAFTGILIAVPDVSQLGIPGVKPEAYRDSRNFGGRDA---D 354
Query: 418 GISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEM 477
G++GLKSLGVRDLTYK+SFLAC V+ +DA+ S D + Q E
Sbjct: 355 GVTGLKSLGVRDLTYKLSFLACMVQ------------PDDANDKSGAD-VRGDGSQGIE- 400
Query: 478 AAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGV 537
+Q+ FL L +EI++L+ MV ++IY +L S+AP+V+GHE IKKGILLQ++ GV
Sbjct: 401 ----EQDEFLQSLSQEEIDDLRAMVHSDHIYSRLTNSLAPSVYGHEIIKKGILLQLMGGV 456
Query: 538 HKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKD 597
HK T EGI LRGD+NICIVGDPSTSKSQFLKYVCNF PRA+YTSGKASSAAGLTAAVVKD
Sbjct: 457 HKLTPEGINLRGDLNICIVGDPSTSKSQFLKYVCNFLPRAIYTSGKASSAAGLTAAVVKD 516
Query: 598 EEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNAR 657
EE GDFTIEAGALMLADNG+C IDEFDKMD++DQVAIHEAMEQQTISIAKAGI ATLNAR
Sbjct: 517 EETGDFTIEAGALMLADNGICAIDEFDKMDLSDQVAIHEAMEQQTISIAKAGIQATLNAR 576
Query: 658 TSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH 717
TSILAAANP+GGRYNRK TLR+N+NMSAPIMSRFDLFFV+LD+CNE +D LA HIVD+H
Sbjct: 577 TSILAAANPIGGRYNRKTTLRNNINMSAPIMSRFDLFFVVLDECNESVDRHLAKHIVDIH 636
Query: 718 MKRDSAINPPFSAEQLSRYINYAKTFKPVMTKEARDYLVKRYTELRKDDAQGYSKSSYRI 777
RD A+ P FS EQL RYI YA+TFKP + E+ +VK+Y +LR DDAQG K+SYRI
Sbjct: 637 RLRDDAMQPEFSTEQLQRYIRYARTFKPKLNTESCAEIVKKYKQLRMDDAQGAGKNSYRI 696
Query: 778 TVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQSXXXXXXXXXXXXXXXNSPEES 837
TVRQLES+IRLSEAIARANCVD+I P+FV EAY LLRQS + +
Sbjct: 697 TVRQLESMIRLSEAIARANCVDDITPAFVNEAYSLLRQS-------------IIHVERDD 743
Query: 838 TEGEGTIPATQHFGETLDTQSQSPSQPLNAD--SETGGGPDVESHDNAHHTTHKVAISYD 895
E E + + +Q L D + T G +V S + KV I+YD
Sbjct: 744 IEVE---------------EDDAEAQELENDNTNTTNGNDNVSSEEALQKP--KVKITYD 786
Query: 896 KYVEMMNLIVRKVVDREKNEEPEMTKTEIVDWYLQQKENDINTEAEYWQERKLAFKVIKR 955
KYV +MN I++ + R + ++V YL+ +E+ +TE + E L KV+ R
Sbjct: 787 KYVSIMNGILQVLRQRSTEGVDGVPAGDLVQSYLELREDQFHTEEDIIYEVGLVRKVLTR 846
Query: 956 LVKDRVLMQIHGQNDDLSADVESSNAKTVYVIHPNCSV 993
LV + ++M+I D + V + V+ IHPNC +
Sbjct: 847 LVHESIIMEIQNLTD---SAVRLPFEERVFSIHPNCDI 881
>Hs7427519 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 821
Score = 635 bits (1637), Expect = 0.0
Identities = 349/749 (46%), Positives = 487/749 (64%), Gaps = 49/749 (6%)
Query: 247 ISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVEQV 306
++F +LPT H+IR++ +++IG L ISG V RT + PEL +F C C+ VI +VEQ
Sbjct: 112 VAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQ 171
Query: 307 FKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGD 366
FKYT+P C NP C N+ + L+ N+S+F+D+QKVRIQE E+P GS+PR+L++ILR +
Sbjct: 172 FKYTQPNICRNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAE 231
Query: 367 CVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLG 426
VE A+ GD+C F GT IVVPDVS+L PG +A + G+ GI GL++LG
Sbjct: 232 AVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYE---TEGIRGLRALG 288
Query: 427 VRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQEIF 486
VRDL+Y++ FLAC V F G + +E+ S ++N +M + +++F
Sbjct: 289 VRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAES------IKN----QMTVKEWEKVF 338
Query: 487 LTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIK 546
EM +D+N+Y L S+ P + G++ +K+G+LL + GV KTT EG
Sbjct: 339 -------------EMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTS 385
Query: 547 LRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIE 606
LRGDIN+CIVGDPST+KSQFLK+V FSPRAVYTSGKASSAAGLTAAVV+DEE +F IE
Sbjct: 386 LRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIE 445
Query: 607 AGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANP 666
AGALMLADNGVCCIDEFDKMD+ DQVAIHEAMEQQTISI KAG+ ATLNARTSILAAANP
Sbjct: 446 AGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANP 505
Query: 667 VGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDSAINP 726
+ G Y+R +L+ N+N+SAPIMSRFDLFF+++D+CNE D +A IVDLH + + +I+
Sbjct: 506 ISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDR 565
Query: 727 PFSAEQLSRYINYAKTFKPVMTKEARDYLVKRYTELRKDDAQGYSKSSYRITVRQLESLI 786
+S + + RY+ +A+ FKP ++KE+ D++V++Y LR+ D G +KSS+RITVRQLES+I
Sbjct: 566 VYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRITVRQLESMI 625
Query: 787 RLSEAIARANCVDEIVPSFVAEAYDLLRQSXXXXXXXXXXXXXXXNSPEESTEGEGTIPA 846
RLSEA+AR +C DE+ P V EA+ LL +S E EG G I
Sbjct: 626 RLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVDEGAGGI-- 683
Query: 847 TQHFGETLDTQSQSPSQPLNADSETGGGPDVESHDNAHHTTHKVAISYDKYVEMMNLIV- 905
+ + SP+ P+N + + ES A + + + +Y + NLIV
Sbjct: 684 --------NGHADSPA-PVNGINGYNEDINQESAPKA-----SLRLGFSEYCRISNLIVL 729
Query: 906 --RKVVDREKNEEPEMTKTEIVDWYLQQKENDINTEAEYWQERKLAFKVIKRLVK-DRVL 962
RKV E+ +E + ++E+V+WYL++ E++I++E E ++++ KVI RL D VL
Sbjct: 730 HLRKV--EEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRLTHYDHVL 787
Query: 963 MQIHGQNDDLSADVESSNAKTVY-VIHPN 990
+++ S + S + Y V++PN
Sbjct: 788 IELTQAGLKGSTEGSESYEEDPYLVVNPN 816
>CE00415 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 810
Score = 615 bits (1585), Expect = e-175
Identities = 363/919 (39%), Positives = 531/919 (57%), Gaps = 135/919 (14%)
Query: 95 KKVDDKTGETVREAFEHFLSNFTALNDETGEMEKVYRVQIEYMRWYELNTIYVDYKHLAE 154
++V+D G V+ F FL +F D+ E +Y+ ++ + E NTI+++ +HL +
Sbjct: 10 QQVEDTDGTRVQNEFSKFLKSF---KDQKNEF--IYKSAMKELVQPEKNTIFINMQHLYK 64
Query: 155 VEDGALAVAILQQYYRFLPFLLSGLRNVVKKYAPGLLLTSDSVLPSQSQENXXXXXXXXX 214
+ LA I QYYR PF+ L L T D+ S+ Q+
Sbjct: 65 FSNN-LATTIELQYYRVYPFMCEALH----------LATLDACDESERQQ---------- 103
Query: 215 XXXLPTSQAATAGGTAPSTIATNPDQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISG 274
++ L +S NL ++R++ A+K+G L+ I+G
Sbjct: 104 -------------------------MFKKQLYVSLFNLDAKTKVRELSADKVGGLVRIAG 138
Query: 275 TVTRTSEIRPELYKASFTCELCRAVIDNVEQVFKYTEPTSCPNPTCENQSFWSLNVNRSK 334
+ RT + PEL +A F CE C +V+Q F+YT+PT C NP C N++ +SL+VN S
Sbjct: 139 QIVRTHPVHPELSRACFVCEDCGVTTRDVQQQFRYTQPTKCANPQCMNRTRFSLDVNSST 198
Query: 335 FLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGL 394
F+D+QK+RIQE E+P GS+PRT+D+I+RG+ VE +PGD+C +GT IV+PD++QL
Sbjct: 199 FVDFQKIRIQETQAELPRGSIPRTVDVIVRGEMVETVQPGDKCDIVGTLIVIPDIAQLST 258
Query: 395 PGVKASSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRIN 454
PG++A ++ +RG R T+ + GI+GLK+LGVRDLTYK++FLACH++ + G
Sbjct: 259 PGLRAETSNQNRG--RATDK-SEGITGLKALGVRDLTYKMAFLACHIQQTESLVGG---- 311
Query: 455 EEDADKTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKS 514
+ + + DY++L +++ +++ LK+M D+ I +V S
Sbjct: 312 -DASGAVEETDYLDL-----------------WSKMSTEDRATLKKMSDDKKIEKNIVDS 353
Query: 515 IAPAVFGHETIKKGILLQMLSGV-HKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNF 573
+ P ++G+ +K G+LL +L GV K+ EG LRGDIN+C+VGDPST+KSQ LK V F
Sbjct: 354 LFPNIYGNHEVKLGVLLMLLGGVAKKSRDEGTSLRGDINVCLVGDPSTAKSQVLKAVEEF 413
Query: 574 SPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVA 633
SPRA+YTSGKASSAAGLTAAVVKDEE +F IEAGALMLADNGVCCIDEFDKMD+ DQVA
Sbjct: 414 SPRAIYTSGKASSAAGLTAAVVKDEESFEFVIEAGALMLADNGVCCIDEFDKMDLKDQVA 473
Query: 634 IHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDL 693
IHEAMEQQTISI KAG+ ATLNAR SILAAANPV GRY+R L+ N+ MSAPIMSRFDL
Sbjct: 474 IHEAMEQQTISITKAGVKATLNARASILAAANPVNGRYDRSRPLKYNVQMSAPIMSRFDL 533
Query: 694 FFVILDDCNEKIDTELASHIVD------LHMKRDSAINPPFSAEQLSRYINYAKTFKPVM 747
FFV++D+CNE D +A I+D H +RDS + + + +YI +A+ FKP +
Sbjct: 534 FFVLVDECNEVTDYAIARRILDNHRAISEHTERDSV----YKIDDIKKYIAFARCFKPKI 589
Query: 748 TKEARDYLVKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVA 807
+ +A + LV+ Y +LR D+ + SS+RITVRQLESL+RLSEA+AR +C E++ V
Sbjct: 590 SDKAAETLVREYKKLRMSDSNNAATSSWRITVRQLESLVRLSEALARLHCGKEVLVEHVE 649
Query: 808 EAYDLLRQSXXXXXXXXXXXXXXXNSPEESTEGEGTIPATQHFGETLDTQSQSPSQPLNA 867
+A +LL +S P+ + + D + + A
Sbjct: 650 KAAELLNKS-----------IVRVEQPDIALD---------------DDDFDNNIMVVEA 683
Query: 868 DSETGGGPDVESHDNAHHTTHKV-----AISYDKYVEMMNLIVRKVVDREKNEEPE---- 918
D E G D HD K+ IS+ +Y ++ +++V + E N+ +
Sbjct: 684 DKENQRGDDSMDHDGEKENAPKIDIAKLKISFKEYKQLSDVLVLHMRSDEDNQGEDEYDG 743
Query: 919 MTKTEIVDWYLQQKENDINTEAEYWQERKLAFKVIKRLV-KDRVLMQIHGQNDDLSADVE 977
+ ++ +V+WYL E D+ TE ++ ++ + +VI RL+ +D VL+++ D
Sbjct: 744 VKQSALVEWYLSTIEADLETEEDFNVQKTICERVIHRLIHQDHVLLEVEQGED------- 796
Query: 978 SSNAKTVYVIHPNCSVLDE 996
+HPN + DE
Sbjct: 797 -----PTLCVHPNYVIADE 810
>7290738 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 817
Score = 597 bits (1539), Expect = e-170
Identities = 362/910 (39%), Positives = 513/910 (55%), Gaps = 123/910 (13%)
Query: 96 KVDDKTGETVREAFEHFLSNFTALNDETGEMEKVYRVQIEYMRWYELNTIYVDYKHLAEV 155
+V D+ G ++ F+ FL F E GE++ Y + + T+ V ++ + E
Sbjct: 12 RVKDEVGIRAQKLFQDFLEEFK----EDGEIK--YTRPAASLESPDRCTLEVSFEDV-EK 64
Query: 156 EDGALAVAILQQYYRFLPFLLSGLRNVVKKYAPGLLLTSDSVLPSQSQENXXXXXXXXXX 215
D LA AI+++YY PFL + N V K GL D
Sbjct: 65 YDQNLATAIIEEYYHIYPFLCQSVSNYV-KDRIGLKTQKDCY------------------ 105
Query: 216 XXLPTSQAATAGGTAPSTIATNPDQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGT 275
++F +PT H++RD+ +KIG+L+ ISG
Sbjct: 106 -------------------------------VAFTEVPTRHKVRDLTTSKIGTLIRISGQ 134
Query: 276 VTRTSEIRPELYKASFTCELCRAVIDNVEQVFKYTEPTSCPNPTCENQSFWSLNVNRSKF 335
V RT + PEL F C C+ I NVEQ FK+T PT C NP C N+ + L+V +S F
Sbjct: 135 VVRTHPVHPELVSGVFMCLDCQTEIRNVEQQFKFTNPTICRNPVCSNRKRFMLDVEKSLF 194
Query: 336 LDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLP 395
LD+QK+RIQE E+P G +PR ++IILR + VE + GDR F GT IVVPDVS L
Sbjct: 195 LDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVVPDVSVLAGV 254
Query: 396 GVKASSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINE 455
G +A ++ SR + EG++ G++GLK+LG+R+L Y+++FLAC V+ F G+ +
Sbjct: 255 GTRAENS--SR--HKPGEGMD-GVTGLKALGMRELNYRMAFLACSVQATTARFGGTDLP- 308
Query: 456 EDADKTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSI 515
+E E ++ E +++ EM KD N+Y L+ S+
Sbjct: 309 ----------------------MSEVTAEDMKKQMTDAEWHKIYEMSKDRNLYQNLISSL 346
Query: 516 APAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSP 575
P+++G++ +K+GILLQ GV KTT E LRGDIN+CIVGDPST+KSQFLK V +FSP
Sbjct: 347 FPSIYGNDEVKRGILLQQFGGVAKTTTEKTSLRGDINVCIVGDPSTAKSQFLKQVSDFSP 406
Query: 576 RAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIH 635
RA+YTSGKASSAAGLTAAVV+DEE DF IEAGALMLADNG+CCIDEFDKMD DQVAIH
Sbjct: 407 RAIYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGICCIDEFDKMDQRDQVAIH 466
Query: 636 EAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFF 695
EAMEQQTISIA+AG+ ATLNARTSILAAANP+ GRY+R +L+ N+ +SAPIMSRFDLFF
Sbjct: 467 EAMEQQTISIARAGVRATLNARTSILAAANPINGRYDRSKSLQQNIQLSAPIMSRFDLFF 526
Query: 696 VILDDCNEKIDTELASHIVDLHMKRDSAINPPFSAEQLSRYINYAKTFKPVMTKEARDYL 755
+++D+CNE +D +A IVDLH + ++ ++ E++ RY+ +A+ FKPV+++EA L
Sbjct: 527 ILVDECNEVVDYAIARKIVDLHSNIEESVERAYTREEVLRYVTFARQFKPVISQEAGHML 586
Query: 756 VKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQ 815
V+ Y LR+ D +S++RITVRQLES+IRLSEA+A+ C + ++ V EA+ LL +
Sbjct: 587 VENYGHLRQRDTGTSGRSTWRITVRQLESMIRLSEAMAKLECSNRVLERHVKEAFRLLNK 646
Query: 816 SXXXXXXXXXXXXXXXNSPEESTEGEGTIPATQHFGETLDTQSQSPSQPLNADSETGGGP 875
S + EG QH D ++ N D G
Sbjct: 647 SIIRVEQPDIHL--------DDDEGLDMDDGIQH-----DIDMENNGAAANVDENNG--- 690
Query: 876 DVESHDNAHHTTHKVAISYDKYVEMMNLIVRKVVDREKNEEPE-----MTKTEIVDWYLQ 930
+++ + K +S++ Y + ++V + E E E + ++ +V WYL+
Sbjct: 691 -MDTSASGAVQKKKFTLSFEDYKNLSTMLVLHMRAEEARCEVEGNDTGIKRSNVVTWYLE 749
Query: 931 QKENDINTEAEYWQERKLAFKVIKRLV-KDRVLM---------QIHGQNDDLSADVESSN 980
Q + I +E E + L K+I RL+ D+V++ +I Q D + D
Sbjct: 750 QVADQIESEDELISRKNLIEKLIDRLIYHDQVIIPLKTSTLKPRIQVQKDFVEED----- 804
Query: 981 AKTVYVIHPN 990
+ V+HPN
Sbjct: 805 -DPLLVVHPN 813
>ECU05g0780 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 726
Score = 514 bits (1325), Expect = e-145
Identities = 271/571 (47%), Positives = 386/571 (67%), Gaps = 52/571 (9%)
Query: 248 SFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVEQVF 307
SF N +++IR++++N++G L++ SGTVTRT+++RPEL +F C++C +VIDNV Q F
Sbjct: 102 SFCNSHVIYKIRELKSNRLGQLLSFSGTVTRTTQVRPELVSGTFVCKICGSVIDNVFQEF 161
Query: 308 KYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDC 367
KYTEP +CPN C N+ W L++++SKFL+WQ++ +QEN+ EIP GS+PR++D+I+R D
Sbjct: 162 KYTEPLTCPNHLCTNRRLWKLDIDKSKFLNWQRIHVQENTEEIPPGSLPRSMDVIVRNDL 221
Query: 368 VERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGV 427
VE+ + GD+ G IVVPDV QL +P ++ S P G S I +++ +
Sbjct: 222 VEKIRAGDKVVMTGYLIVVPDVVQLMMP--QSKSVPMQSGES-------DEIRKKRNINI 272
Query: 428 RDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQEIFL 487
+DL +K+SF+ H G S EED + T
Sbjct: 273 KDLNHKLSFMCIH---AGCSV------EEDEEFT-------------------------- 297
Query: 488 TRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKL 547
++E+ + EM ++Y KL +S+ P++ GH +IK ILL ++ GV K G +L
Sbjct: 298 ----NEELATISEMRSTPDLYYKLSQSMFPSIHGHYSIKNAILLLLVGGVGKRAEGGTRL 353
Query: 548 RGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEA 607
RGDIN+ +VGDP T+KSQFLK F PR+VYTSGK+SSAAGLTA+VVKD E G+FTIEA
Sbjct: 354 RGDINMLLVGDPGTAKSQFLKQASAFLPRSVYTSGKSSSAAGLTASVVKDGETGEFTIEA 413
Query: 608 GALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPV 667
GALML+D GVCCIDEFDKM++ DQV+IHEAMEQQTI+I+KAGI+ATLNAR+SILAAANP+
Sbjct: 414 GALMLSDTGVCCIDEFDKMNVKDQVSIHEAMEQQTITISKAGINATLNARSSILAAANPI 473
Query: 668 GGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMK-RDSAINP 726
GRY++K TLR N+N+SAP+MSRFDL+FV++DD + + D +A+H+++ H DS +
Sbjct: 474 KGRYDKKKTLRQNINLSAPVMSRFDLYFVLIDDADPENDRNVATHVLNSHASVTDSGVLA 533
Query: 727 P-FSAEQLSRYINYAKTFKPVMTKEARDYLVKRYTELRKDDAQGYSKSSYRITVRQLESL 785
F+ EQ+ Y+ YA+ P MT EA++ L+KRY +R+D ++Y +TVR LESL
Sbjct: 534 SYFTREQVKLYLRYARKKTPRMTAEAKEMLIKRYVGIRQDSL--IHSNNYMMTVRHLESL 591
Query: 786 IRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
IRLSEA+A+ + D + +V EA+ L++ S
Sbjct: 592 IRLSEALAKVHDNDLVTKEYVEEAHRLVKSS 622
>SPBC25D12.03c [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 760
Score = 355 bits (910), Expect = 3e-97
Identities = 206/568 (36%), Positives = 314/568 (55%), Gaps = 80/568 (14%)
Query: 258 IRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVEQVFKYTEPTSCPN 317
+RD+R +GSL+ + G VTRTS+++P L ++TC+ C + + + + CP+
Sbjct: 170 VRDLRGENLGSLLTVRGIVTRTSDVKPSLTVNAYTCDRCGYEVFQEIRQKTFLPMSECPS 229
Query: 318 PTCENQSFWS---LNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPG 374
C+ ++ SKFL +Q+V+IQE +N++P G +PR+L + L G PG
Sbjct: 230 DECKKNDAKGQLFMSTRASKFLPFQEVKIQELTNQVPIGHIPRSLTVHLYGAITRSVNPG 289
Query: 375 DRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKI 434
D + D+S + LP TP +G +++ LT
Sbjct: 290 D----------IVDISGIFLP------TP---------------YTGFRAMRAGLLTD-- 316
Query: 435 SFLACHVENVGTSFNGSRINEEDADKTSKFDYIN--LRNYQNYEMAAETDQEIFLTRLDS 492
++L CH Y++ ++NY N E +++ I
Sbjct: 317 TYLECH-------------------------YVSQIIKNYTNIEKTPQSEAAI------- 344
Query: 493 DEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDIN 552
E+ + N+Y+KL KSIAP ++GHE +KK +LL ++ GV K +G+++RGDIN
Sbjct: 345 ------AELNQGGNVYEKLAKSIAPEIYGHEDVKKALLLLLVGGVTKELGDGMRIRGDIN 398
Query: 553 ICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALML 612
IC+ GDP +KSQ LKY+ +PR VYT+G+ SS GLTAAV++D + +E GAL+L
Sbjct: 399 ICLTGDPGVAKSQLLKYISKVAPRGVYTTGRGSSGVGLTAAVMRDPVTDEMVLEGGALVL 458
Query: 613 ADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYN 672
ADNG+CCIDEFDKMD +D+ AIHE MEQQTISI+KAGI TLNARTSILAAANP+ GRYN
Sbjct: 459 ADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGITTTLNARTSILAAANPLYGRYN 518
Query: 673 RKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDSAIN--PPFSA 730
K+ N+N+ A ++SRFD+ F+ILD + + D LA H+ +HM + P
Sbjct: 519 PKVAPIHNINLPAALLSRFDILFLILDTPSRETDEHLAQHVTYVHMHNEQPKMDFEPLDP 578
Query: 731 EQLSRYINYAKTFKPVMTKEARDYLVKRYTELRKDDA--QGYSKSSYRITVRQLESLIRL 788
+ YI+ A+ ++PV+ K+ DY+ Y +LR++ + + T R L +++R+
Sbjct: 579 NMIRHYISSARQYRPVVPKDVCDYVTGAYVQLRQNQKRDEANERQFAHTTPRTLLAILRM 638
Query: 789 SEAIARANCVDEIVPSFVAEAYDLLRQS 816
+A+AR + + V EA L+ S
Sbjct: 639 GQALARLRFSNRVEIGDVDEALRLMSVS 666
>7295030 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 720
Score = 347 bits (889), Expect = 7e-95
Identities = 241/720 (33%), Positives = 358/720 (49%), Gaps = 98/720 (13%)
Query: 106 REAFEHFLSNFTALNDETGEMEKVYRVQIEYMRWYELNTIYVDYKHLAEVEDGALAVAIL 165
RE+ + FLS F +D+ G+ E VY Q+ + E I +D LAE + +LA A++
Sbjct: 10 RESIKTFLSEFCKCDDD-GKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNE-SLAEAVV 67
Query: 166 QQYYRFLPFLLSGLRNVVKKYAPGLLLTSDSVLPSQSQENXXXXXXXXXXXXLPTSQAAT 225
R+ S +V+ + +LPS Q+ +
Sbjct: 68 DNCRRYT----SIFSDVIAE-----------LLPSYKQQEVHAKDALDVYIEHRLMMESR 112
Query: 226 AGGTAPSTIATN--PDQVERVLQISFLNLPT--VHRIRDIRANKIGSLMAISGTVTRTSE 281
N P ++ + ++ F L T H IR+++A IG L+ + G VTR +E
Sbjct: 113 TRNPMEQRDERNSFPSELMKRFEVGFKPLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTE 172
Query: 282 IRPELYKASFTCELCRAVIDNVEQVFKYTEPTSCPNPTCENQSFWS---LNVNRSKFLDW 338
++P + A++TC+ C + +T CP+ C L SKF+ +
Sbjct: 173 VKPMMVVATYTCDRCGSETYQPVNSLSFTPVHDCPSDDCRVNKAGGRLYLQTRGSKFVKF 232
Query: 339 QKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVK 398
Q+V++QE+S+++P G +PR++ I+ RG+ A+PGD VS + LP ++
Sbjct: 233 QEVKMQEHSDQVPVGHIPRSMTIMCRGEVTRMAQPGDHIV----------VSGVFLPLMR 282
Query: 399 ASSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDA 458
G ++ +GL S +FL H + I+++DA
Sbjct: 283 T-------GFAQMIQGLLSE----------------TFLQAH--RIICINKNDEISDKDA 317
Query: 459 DKTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPA 518
+ T + EL+E+ +D+ Y++L S+AP
Sbjct: 318 ELTPE---------------------------------ELEELAQDD-FYERLATSLAPE 343
Query: 519 VFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAV 578
++GH +KK +LL ++ GV K +G+K+RG+INIC++GDP +KSQ L Y+ + R+
Sbjct: 344 IYGHLDVKKALLLLLVGGVDKRP-DGMKIRGNINICLMGDPGVAKSQLLGYISRLAVRSQ 402
Query: 579 YTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAM 638
YT+G+ SS GLTAAV+KD G+ T+E GAL+LAD GVCCIDEFDKM D+ AIHE M
Sbjct: 403 YTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGVCCIDEFDKMADQDRTAIHEVM 462
Query: 639 EQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVIL 698
EQQTISIAKAGI TLNAR SILAAANP GRYN + T+ N+ + A ++SRFDL ++I
Sbjct: 463 EQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNIQLPAALLSRFDLLWLIQ 522
Query: 699 DDCNEKIDTELASHI--VDLHMKRDSAINPPFSAEQLSRYINYAKTFKPVMTKEARDYLV 756
D + D LA HI V H K+ + RYIN K P + E DY+V
Sbjct: 523 DKPDRDNDLRLAKHITYVHSHSKQPPTRVKALDMNLMRRYINLCKRKNPTIPDELTDYIV 582
Query: 757 KRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
Y ELR++ K + R L ++RLS A+AR D + VAEA LL S
Sbjct: 583 GAYVELRREARN--QKDMTFTSARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLEMS 640
>At2g16440 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 720
Score = 342 bits (878), Expect = 1e-93
Identities = 214/579 (36%), Positives = 317/579 (53%), Gaps = 66/579 (11%)
Query: 242 ERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVID 301
E+ +Q+ NL T +R++ + I ++++ G + R+S I PE+ +A F C +C D
Sbjct: 123 EKHVQVRIFNLRTSTSMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGYFSD 182
Query: 302 NV-EQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLD 360
+ K +EP +C C ++ +L NR +F D Q VR+QE +EIP G P T+
Sbjct: 183 PIIVDRGKISEPPTCLKQECMTKNSMTLVHNRCRFADKQIVRLQETPDEIPEGGTPHTVS 242
Query: 361 IILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGIS 420
++L V+ G PG + T GI R
Sbjct: 243 LLLHDKLVDN----------------------GKPGDRIEVT----GIYRA--------- 267
Query: 421 GLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAE 480
+T ++ V++V ++ D ++++ M+AE
Sbjct: 268 ---------MTVRVGPAHRTVKSVFKTY---------------IDCLHIKKASKLRMSAE 303
Query: 481 TDQEI--FLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVH 538
++ L R+D D + + +E+ K +IY++L +S+AP ++ + +KKG+L Q+ G
Sbjct: 304 DPMDVDNSLRRVDED-LRKFQELSKQPDIYERLSRSLAPNIWELDDVKKGLLCQLFGGNA 362
Query: 539 KTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDE 598
G RGDINI +VGDP TSKSQ L+Y+ SPR +YTSG+ SSA GLTA V KD
Sbjct: 363 LNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAYVAKDP 422
Query: 599 EGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNART 658
E G+ +E+GAL+L+D G+CCIDEFDKM + + +HE MEQQT+SIAKAGI A+LNART
Sbjct: 423 ETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIASLNART 482
Query: 659 SILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHM 718
S+LA ANP G RYN +L++ N+++ ++SRFDL ++ILD +E+ D LA HIV LH
Sbjct: 483 SVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRLAKHIVALHF 542
Query: 719 KR-DSAINPPFSAEQLSRYINYA-KTFKPVMTKEARDYLVKRYTELRK-DDAQGYSKSSY 775
+ +SA L+ Y++YA K P ++ EA + L + Y ELRK G SK
Sbjct: 543 ENAESAQEEAIDITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKAGKFAGSSKKVI 602
Query: 776 RITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLR 814
T RQ+ESLIRLSEA+AR + + V EA+ LLR
Sbjct: 603 TATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLR 641
>YPR019w [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 933
Score = 338 bits (866), Expect = 3e-92
Identities = 214/589 (36%), Positives = 322/589 (54%), Gaps = 61/589 (10%)
Query: 239 DQVE-RVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCR 297
D++E + ++ N+ + +R++ N I L+ + G V R++ + P++ A F C +C
Sbjct: 294 DEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCD 353
Query: 298 AVIDNVEQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPR 357
+ EP C C + SL NR F D Q +++QE + +P G P
Sbjct: 354 HTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPH 413
Query: 358 TLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNS 417
++ + + + V+ + GDR + GT +P ++A NS
Sbjct: 414 SISLCVYDELVDSCRAGDRIEVTGTFRSIP---------IRA----------------NS 448
Query: 418 GISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEM 477
LKSL YK HV+ V D D TS + ++N ++
Sbjct: 449 RQRVLKSL------YKTYVDVVHVKKVSDK-------RLDVD-TSTIEQELMQNKVDHNE 494
Query: 478 AAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGV 537
E Q + ++ +++E+ E++Y L +SIAP+++ E +KKGILLQ+ G
Sbjct: 495 VEEVRQ------ITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGT 548
Query: 538 HKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKD 597
+KT +G + RGDINI + GDPSTSKSQ L+YV +PR VYTSGK SSA GLTA + +D
Sbjct: 549 NKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRD 608
Query: 598 EEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNAR 657
+ +E+GAL+L+D GVCCIDEFDKM + + +HE MEQQTISIAKAGI TLNAR
Sbjct: 609 VDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNAR 668
Query: 658 TSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDL- 716
+SILA+ANP+G RYN L + N+++ P++SRFDL +++LD +EK D ELA H+ +L
Sbjct: 669 SSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLY 728
Query: 717 ------HMKRDSAINPPFSAEQLSRYINYAKT-FKPVMTKEARDYLVKRYTELRK--DDA 767
H+ +D + E L+ YI+YAK P++T+ A+ LV+ Y +RK DD+
Sbjct: 729 LEDKPEHISQDDVL----PVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDS 784
Query: 768 QGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
+ K T RQLES+IRL+EA A+ + + V EA L+R +
Sbjct: 785 RSDEK-RITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSA 832
>Hs21359886 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 719
Score = 337 bits (865), Expect = 4e-92
Identities = 232/719 (32%), Positives = 364/719 (50%), Gaps = 96/719 (13%)
Query: 106 REAFEHFLSNFTALNDETGEMEKVYRVQIEYMRWYELNTIYVDYKHLAEVEDGALAVAIL 165
+E + FL F +DE G+ + Y Q+ + E +YVD +AE +D L +I
Sbjct: 10 KEKVKKFLQEFYQ-DDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAE-DDPELVDSIC 67
Query: 166 QQYYRFLPFLLSGLRNVVKKYAPGLLLTSDSVLPSQSQENXXXXXXXXXXXXLPTSQAAT 225
+ R+ ++ ++ +Y ++ D VL + L Q +
Sbjct: 68 ENARRYAKLFADAVQELLPQYKEREVVNKD-VLDVYIEHR------------LMMEQRSR 114
Query: 226 AGGTAPSTIATNPDQVERVLQISFLNLPTVHR---IRDIRANKIGSLMAISGTVTRTSEI 282
G S P ++ R ++ F P+ + IR++RA+ +G L+ + G VTR SE+
Sbjct: 115 DPGMVRSPQNQYPAELMRRFELYFQG-PSSSKPRVIREVRADSVGKLVTVRGIVTRVSEV 173
Query: 283 RPELYKASFTCELCRAVIDNVEQVFKYTEPTSCPNPTCENQSFWS---LNVNRSKFLDWQ 339
+P++ A++TC+ C A Q + CP+ C+ L S+F+ +Q
Sbjct: 174 KPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQ 233
Query: 340 KVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKA 399
++++QE+S+++P G++PR++ +++ G + +++ PG
Sbjct: 234 EMKMQEHSDQVPVGNIPRSITVLVEG----------------------ENTRIAQPGDHV 271
Query: 400 SSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDAD 459
S T I RT G + GL S TY
Sbjct: 272 SVTGIFLPILRT--GFRQVVQGLLSE-----TY--------------------------- 297
Query: 460 KTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAV 519
L ++ +M D E L +E+ ++ E E+ Y+KL SIAP +
Sbjct: 298 ---------LEAHRIVKMNKSEDDESGAGELTREELRQIAE----EDFYEKLAASIAPEI 344
Query: 520 FGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVY 579
+GHE +KK +LL ++ GV ++ G+K+RG+INIC++GDP +KSQ L Y+ +PR+ Y
Sbjct: 345 YGHEDVKKALLLLLVGGVDQSP-RGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQY 403
Query: 580 TSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAME 639
T+G+ SS GLTAAV++D G+ T+E GAL+LAD GVCCIDEFDKM AD+ AIHE ME
Sbjct: 404 TTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVME 463
Query: 640 QQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILD 699
QQTISIAKAGI TLNAR SILAAANP GRYN + +L N+ + A ++SRFDL ++I D
Sbjct: 464 QQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQD 523
Query: 700 DCNEKIDTELASHI--VDLHMKRDSAINPPFSAEQLSRYINYAKTFKPVMTKEARDYLVK 757
+ D LA HI V H ++ + P + + RYI + +P++ + DY+
Sbjct: 524 RPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITA 583
Query: 758 RYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
Y E+R++ SK + + R L +++RLS A+AR VD + V EA L+ S
Sbjct: 584 AYVEMRRE--AWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 640
>YBR202w [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 845
Score = 336 bits (861), Expect = 1e-91
Identities = 200/566 (35%), Positives = 312/566 (54%), Gaps = 76/566 (13%)
Query: 258 IRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVEQVFKYTEPTSCPN 317
+R I+ + +G L+ + G +TR S+++P + ++TC+ C + +T + C +
Sbjct: 227 VRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTS 286
Query: 318 PTC-ENQSFWSL--NVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPG 374
C +NQ+ L + SKF +Q+ +IQE S ++P G +PR+L+I + G V PG
Sbjct: 287 EECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPG 346
Query: 375 DRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKI 434
D + DV+ + LP +G LK+ + + +
Sbjct: 347 D----------IVDVTGIFLPAP------------------YTGFKALKAGLLTETYLEA 378
Query: 435 SFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSDE 494
F+ H + + ++ + ++ ++ +
Sbjct: 379 QFVRQH----------------------------KKKFASFSLTSDVEERVM-------- 402
Query: 495 INELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINIC 554
E++ ++Y++L KSIAP ++G+ +KK +LL ++ GV K +G+K+RGDIN+C
Sbjct: 403 -----ELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVC 457
Query: 555 IVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLAD 614
++GDP +KSQ LK +C SPR VYT+GK SS GLTAAV+KD + +E GAL+LAD
Sbjct: 458 LMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLAD 517
Query: 615 NGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRK 674
NG+CCIDEFDKMD +D+ AIHE MEQQTISI+KA I+ ARTSILAAANP+ GR N +
Sbjct: 518 NGICCIDEFDKMDESDRTAIHEVMEQQTISISKAVINTNPGARTSILAAANPLYGRINPR 577
Query: 675 LTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHI--VDLHMKRDSAINPPFSAEQ 732
L+ N+N+ A ++SRFD+ F++LD + D +LA H+ V +H K+ P +
Sbjct: 578 LSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSK 637
Query: 733 LSRYINYAKTFKPVMTKEARDYLVKRYTELRKDDAQGY-SKSSY-RITVRQLESLIRLSE 790
+ YI YAKT +PVM++ DY+V+ Y LR+D + SK S+ + T R L +IRLS+
Sbjct: 638 MREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQ 697
Query: 791 AIARANCVDEIVPSFVAEAYDLLRQS 816
A+A+ D + V EA L+R S
Sbjct: 698 ALAKLRLADMVDIDDVEEALRLVRVS 723
>At4g02060 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 716
Score = 330 bits (847), Expect = 5e-90
Identities = 225/716 (31%), Positives = 348/716 (48%), Gaps = 106/716 (14%)
Query: 112 FLSNFTALNDETGEMEKVYRVQIEYMRWYELNTIYVDYKHLAEVEDGALAVAILQQYYRF 171
FL NF N + ME + V +R I VD L +D + F
Sbjct: 16 FLENFADANGRSKYMEILQEVSNRKIR-----AIQVDLDDLFNYKD---------ESEEF 61
Query: 172 LPFLLSGLRNVVKKYAPGLLLTSDSVLPSQSQENXXXXXXXXXXXXLPTSQAATAGGTAP 231
L L R V ++ + D +LP ++ + +Q A G P
Sbjct: 62 LGRLTENTRRYVSIFSAAV----DELLPEPTE------AFPDDDHDILMTQRADDGTDNP 111
Query: 232 STIATN---PDQVERVLQISFLNLPTVHR---IRDIRANKIGSLMAISGTVTRTSEIRPE 285
+ P +++R ++ F P+ R IR+++A+ IG L+ ISG VTR S+++P
Sbjct: 112 DVSDPHQQIPSEIKRYYEVYF-KAPSKGRPSTIREVKASHIGQLVRISGIVTRCSDVKPL 170
Query: 286 LYKASFTCELCRAVIDNVEQVFKYTEPTSCPNPTCENQSFWS---LNVNRSKFLDWQKVR 342
+ A +TCE C I + CP+ C S L + SKFL +Q+ +
Sbjct: 171 MAVAVYTCEDCGHEIYQEVTSRVFMPLFKCPSSRCRLNSKAGNPILQLRASKFLKFQEAK 230
Query: 343 IQENSNEIPSGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASST 402
+QE + +P G +PR++ + LRG+ + PGD +F G + +P G ++A
Sbjct: 231 MQELAEHVPKGHIPRSMTVHLRGELTRKVSPGDVVEFSGIFLPIP---YTGFKALRAGLV 287
Query: 403 PDSRGISRTTEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTS 462
D TY + H + + + EE + +
Sbjct: 288 AD--------------------------TYLEATSVTHFKKKYEEYEFQKDEEEQIARLA 321
Query: 463 KFDYINLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGH 522
+ D D N+L + E ++GH
Sbjct: 322 E---------------------------DGDIYNKLSRSLAPE-------------IYGH 341
Query: 523 ETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSG 582
E IKK +LL ++ H+ +G+K+RGD++IC++GDP +KSQ LK++ N +PR VYT+G
Sbjct: 342 EDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTG 401
Query: 583 KASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQT 642
K SS GLTAAV++D+ + +E GAL+LAD G+C IDEFDKMD +D+ AIHE MEQQT
Sbjct: 402 KGSSGVGLTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQT 461
Query: 643 ISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCN 702
+SIAKAGI +LNART++LAAANP GRY+ + T N+N+ ++SRFDL ++ILD +
Sbjct: 462 VSIAKAGITTSLNARTAVLAAANPAWGRYDLRRTPAENINLPPALLSRFDLLWLILDRAD 521
Query: 703 EKIDTELASHIVDLHMKRDSAI--NPPFSAEQLSRYINYAKTFKPVMTKEARDYLVKRYT 760
D ELA H++ +H +S P L YI+ A+ P + E +Y+ Y+
Sbjct: 522 MDSDLELAKHVLHVHQTEESPALGFEPLEPNILRAYISAARRLSPYVPAELEEYIATAYS 581
Query: 761 ELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
+R+++A+ + SY TVR L S++R+S A+AR + + S V EA L++ S
Sbjct: 582 SIRQEEAKSNTPHSY-TTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMS 636
>CE21767 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 823
Score = 327 bits (839), Expect = 4e-89
Identities = 205/577 (35%), Positives = 304/577 (52%), Gaps = 74/577 (12%)
Query: 245 LQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVE 304
+++ N +R + N + L+ ISG VTRTS + PE+ F C +C I++
Sbjct: 221 IELRPFNAQKTRNMRGLNPNDVDQLITISGMVTRTSSLIPEMRSGYFQCAVCAFGIESEV 280
Query: 305 QVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILR 364
+ EP C N C N + L NRS FLD Q V++QE+ +++PSG P T+ +
Sbjct: 281 DKGRIEEPVVCTN--CSNTHCFQLVHNRSVFLDKQVVKLQESPDDMPSGETPHTVSVYAH 338
Query: 365 GDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKS 424
G VE +PGDR G G+K + P R ++
Sbjct: 339 GSLVESVQPGDRITVTGI---------FRATGMKVN--PKQRALASV------------- 374
Query: 425 LGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQE 484
Y+ S A H + TS R+++++ + ++
Sbjct: 375 -------YRTSIDALHFRKMDTS----RLHQDNGETITE--------------------- 402
Query: 485 IFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKT--TV 542
+ I ++ E+ K +I D L +SIAP+++ H+ +K+G+L + G K T
Sbjct: 403 --------ERIQQIIELSKRPDIMDALAQSIAPSIYEHDDVKRGLLCLLFGGTRKDDETT 454
Query: 543 EGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGD 602
KLR +INI + GDP TSKSQ L+YV PR+ YTSGK SSA GLTA+V +D +
Sbjct: 455 NKTKLRSEINILLCGDPGTSKSQMLQYVYRLLPRSQYTSGKGSSAVGLTASVSRDADTKQ 514
Query: 603 FTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILA 662
++ GAL+LADNGVCCIDEFDKM+ + + +HE MEQQT+SIAKAGI LNAR S+LA
Sbjct: 515 LVLQTGALVLADNGVCCIDEFDKMNESARSVLHEVMEQQTLSIAKAGIICQLNARASVLA 574
Query: 663 AANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDS 722
AANPV ++NR T+ N+ + ++SRFDL F+I+D +E D L +H+V L+ + D
Sbjct: 575 AANPVDSKWNRNKTIVENITLPHTLLSRFDLIFLIVDAQDEMQDRRLGNHLVSLYFENDG 634
Query: 723 AINPPFSAEQ--LSRYINYAK-TFKPVMTKEARDYLVKRYTELRKDDAQGYSKSSYRITV 779
+ L YI YAK P +++EA +++++Y +RK AQ ++Y
Sbjct: 635 NQEKTEHVDMNLLRDYIAYAKANIHPKLSEEASQFIIEKYLFMRKAGAQHGQITAY---P 691
Query: 780 RQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
RQLESLIRLSEA A+ E+ V +A+ L R++
Sbjct: 692 RQLESLIRLSEAHAKIRLSQEVSVDDVEKAFTLWREA 728
>Hs14738665 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 863
Score = 322 bits (824), Expect = 2e-87
Identities = 211/585 (36%), Positives = 303/585 (51%), Gaps = 72/585 (12%)
Query: 238 PDQV-ERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELC 296
PD + E +Q+ N +R++ I L+ ISG V RTS++ PE+ +A F C++C
Sbjct: 250 PDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVC 309
Query: 297 RAVIDNVEQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMP 356
+ EP+ C C +L NRS F D Q +++QE+ ++P+G P
Sbjct: 310 AHTTRVEMDRGRIAEPSVCGR--CHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTP 367
Query: 357 RTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLN 416
T+ + D V++ +PGDR G VP +N
Sbjct: 368 HTVILFAHNDLVDKVQPGDRVNVTGIYRAVPI-------------------------RVN 402
Query: 417 SGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYE 476
+S +KS+ YK H DA + D
Sbjct: 403 PRVSNVKSV------YKTHIDVIHYRKT------------DAKRLHGLD----------- 433
Query: 477 MAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSG 536
E +Q++F + + LKE+ + +IY++L ++AP+++ HE IKKGILLQ+ G
Sbjct: 434 --EEAEQKLFSEK----RVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGG 487
Query: 537 VHKT---TVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAA 593
K T G K R +INI + GDP TSKSQ L+YV N PR YTSGK SSA GLTA
Sbjct: 488 TRKDFSHTGRG-KFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAY 546
Query: 594 VVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHAT 653
V+KD E ++ GAL+L+DNG+CCIDEFDKM+ + + +HE MEQQT+SIAKAGI
Sbjct: 547 VMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQ 606
Query: 654 LNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHI 713
LNARTS+LAAANP+ ++N K T N+ + ++SRFDL F++LD +E D LA H+
Sbjct: 607 LNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHL 666
Query: 714 VDL-HMKRDSAINPPFSAEQLSRYINYA-KTFKPVMTKEARDYLVKRYTELRKDDAQGYS 771
V L + + A L YI YA T P +++EA L++ Y ++RK G S
Sbjct: 667 VALYYQSEEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRK---IGSS 723
Query: 772 KSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
+ RQLESLIRL+EA A+ +++ V EA L R++
Sbjct: 724 RGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREA 768
>7304207 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 866
Score = 316 bits (810), Expect = 1e-85
Identities = 203/580 (35%), Positives = 302/580 (52%), Gaps = 70/580 (12%)
Query: 241 VERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVI 300
+E +Q+ N +R + + L++ISG V R+S + PE+ +A F+C +C
Sbjct: 257 LEHQIQVRPFNADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFST 316
Query: 301 DNVEQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLD 360
+ +PT C N C + L NRS+F D Q V++QE+ +++ +G P +
Sbjct: 317 TVEVDRGRINQPTLCTN--CNTNHCFRLIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVL 374
Query: 361 IILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGIS 420
+ D V++ +PGDR G P T GL+S +
Sbjct: 375 LYAHNDLVDKVQPGDRVTVTGIYRATP----------------------LKTGGLSSSVK 412
Query: 421 GLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAE 480
+ YK H V + R+ E++ K F
Sbjct: 413 SV---------YKTHVDVVHFRKV----DNKRLYEDEEGKDHIFP--------------- 444
Query: 481 TDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHK- 539
+ + L+ + K +IYD+L ++IAP+++ ++ IKKGILLQ+ G K
Sbjct: 445 -----------PERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKK 493
Query: 540 -TTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDE 598
T+ R +I++ + GDP TSKSQ L+YV N PR+ YTSG+ SSA GLTA V KD
Sbjct: 494 HATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDP 553
Query: 599 EGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNART 658
E ++ GAL+LADNGVCCIDEFDKM+ + + +HE MEQQT+SIAKAGI LNART
Sbjct: 554 ETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNART 613
Query: 659 SILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDL-H 717
SILAAANP ++N++ + N+ + ++SRFDL F++LD +E D LASH+V L +
Sbjct: 614 SILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYY 673
Query: 718 MKRDSAINPPFSAEQLSRYINYAKT-FKPVMTKEARDYLVKRYTELRKDDAQGYSKSSYR 776
+ R + F L YI YA+ P ++ EA+ L++ Y ++RK A S+Y
Sbjct: 674 VTRHEEEDTMFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVGAGRGQISAY- 732
Query: 777 ITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
RQLESLIRLSEA A+ +++ V EA+ L R++
Sbjct: 733 --PRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREA 770
>ECU02g1150 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 708
Score = 311 bits (798), Expect = 2e-84
Identities = 203/561 (36%), Positives = 296/561 (52%), Gaps = 85/561 (15%)
Query: 258 IRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELC--RAVIDNVEQVFKYTEPTSC 315
IR+I N I ++ ISG V R+S + PE+ +A F C C ++++V V EP C
Sbjct: 143 IRNIDPNDIDKIVQISGMVIRSSSVIPEIVRAFFRCSRCGHECLVESVRNVID--EPNKC 200
Query: 316 PNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPGD 375
C + L N S+F D Q VRIQE IP+G+ P + I+ R + V+ PGD
Sbjct: 201 E---CGGKYTQQLVHNASEFEDKQVVRIQELPEGIPNGTTPMAMTIVCRNEFVDGLVPGD 257
Query: 376 RCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKIS 435
R K L GV + T LN + +KS T++I
Sbjct: 258 RVK---------------LTGV----------LKATPVRLNPVMRKIKS------TFRI- 285
Query: 436 FLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSDEI 495
Y++L +YQ E+ SD I
Sbjct: 286 ------------------------------YLDLLSYQVINRKIES----------SDPI 305
Query: 496 NELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICI 555
+++ E+ K ++Y+ L S+AP+V G E KK ++LQ+ GV K + +LRGDINI +
Sbjct: 306 DKIDELRKRPDVYEILANSVAPSVCGMEDTKKALVLQLFGGVRKE-LGSSRLRGDINILL 364
Query: 556 VGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADN 615
GDP SKSQ L ++ S R +YTSG+ SSA GLTA+V KD + G F +E+GAL+L+DN
Sbjct: 365 AGDPGISKSQLLSFIHRTSERGMYTSGRGSSAVGLTASVAKDPDTGQFILESGALVLSDN 424
Query: 616 GVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKL 675
G+CCIDEFDKM + + +HE MEQQT+S+AKAGI TLNAR SILA+ NP+ +YN +
Sbjct: 425 GICCIDEFDKMSDSTRSVLHEVMEQQTVSVAKAGIITTLNARCSILASCNPIESKYNPRK 484
Query: 676 TLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDSAINPPFSAEQLSR 735
++ N+N+ ++SRFD+ +++D C+E D + HIV L+ ++ A+ L
Sbjct: 485 SIVENINLPPTLLSRFDVVCLMIDRCDEFYDRTIGDHIVSLY-SEETQRKEYIDADLLKA 543
Query: 736 YINYAKTFKPVMTKEARDYLVKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARA 795
Y+ A+ P +T E+ L + Y +LR+ D + + T RQLESLIRLSEA AR
Sbjct: 544 YVREARRIVPRLTPESMKMLTQSYVDLRQMD----NGKTITATTRQLESLIRLSEAHARM 599
Query: 796 NCVDEIVPSFVAEAYDLLRQS 816
+ + V EA ++R+S
Sbjct: 600 RFSNAVEAKDVREAVRIIRES 620
>Hs6631095 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 808
Score = 303 bits (777), Expect = 7e-82
Identities = 203/632 (32%), Positives = 310/632 (48%), Gaps = 131/632 (20%)
Query: 266 IGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVEQVFKYTE-------PTSCPNP 318
+ ++ + G VT+ S +RP++ ++ C + I+ +Y++ P+S P
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIER-----RYSDLTTLVAFPSSSVYP 175
Query: 319 TCENQSF-WSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPGDRC 377
T + ++ S + D Q + IQE + P+G +PR++D+IL D V++AKPGDR
Sbjct: 176 TKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRV 235
Query: 378 KFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKISFL 437
+ +GT LPG K G SG T++ +
Sbjct: 236 QVVGTYRC--------LPGKKG--------------GYTSG------------TFRTVLI 261
Query: 438 ACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSDEINE 497
AC+V+ + S + ED K KF
Sbjct: 262 ACNVKQMSKDAQPS-FSAEDIAKIKKFS-------------------------------- 288
Query: 498 LKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVG 557
+ ++I+D+L KS+AP++ GH+ +KK IL +L GV + G +RGDINI ++G
Sbjct: 289 ---KTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIG 345
Query: 558 DPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGV 617
DPS +KSQ L+YV +PRA+ T+G+ SS GLTAAV D+E G+ +EAGA++LAD GV
Sbjct: 346 DPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGV 405
Query: 618 CCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLTL 677
CIDEFDKM D+ AIHE MEQ ++IAKAGIHA LNAR S+LAAANPV GRY++ T
Sbjct: 406 VCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTP 465
Query: 678 RSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH------------MKRDSAI- 724
N+ + ++SRFDL F++LD + + D E++ H++ +H M SA+
Sbjct: 466 MENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVD 525
Query: 725 -----NPPFSAEQ-----------------------------LSRYINYAKTFKPVMTKE 750
+P FS E + +YI+ AK KPV+T+E
Sbjct: 526 ILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQE 585
Query: 751 ARDYLVKRYTELRKDDAQGYSKS-SYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEA 809
+ Y+ + Y+ LR D+ + + +T R LE+LIRL+ A A+A + EA
Sbjct: 586 SATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEA 645
Query: 810 YDLLRQSXXXXXXXXXXXXXXXNSPEESTEGE 841
+L++ + + E TE E
Sbjct: 646 VELVQYAYFKKVLEKEKKRKKRSEDESETEDE 677
>HsM14149623 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 543
Score = 297 bits (761), Expect = 5e-80
Identities = 188/533 (35%), Positives = 282/533 (52%), Gaps = 77/533 (14%)
Query: 289 ASFTCELCRAVIDNVEQVFKYTEPTSCPNPTCENQSFWS---LNVNRSKFLDWQKVRIQE 345
A++TC+ C A Q + CP+ C+ L S+F+ +Q++++QE
Sbjct: 4 ATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQE 63
Query: 346 NSNEIPSGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDS 405
+S+++P G++PR++ +++ G + +++ PG S T
Sbjct: 64 HSDQVPVGNIPRSITVLVEG----------------------ENTRIAQPGDHVSVTGIF 101
Query: 406 RGISRTTEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFD 465
I RT G + GL S TY
Sbjct: 102 LPILRT--GFRQVVQGLLSE-----TY--------------------------------- 121
Query: 466 YINLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETI 525
L ++ +M D E L +E+ ++ E E+ Y+KL SIAP ++GHE +
Sbjct: 122 ---LEAHRIVKMNKSEDDESGAGELTREELRQIAE----EDFYEKLAASIAPEIYGHEDV 174
Query: 526 KKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKAS 585
KK +LL ++ GV ++ G+K+RG+INIC++GDP +KSQ L Y+ +PR+ YT+G+ S
Sbjct: 175 KKALLLLLVGGVDQSP-RGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGS 233
Query: 586 SAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISI 645
S GLTAAV++D G+ T+E GAL+LAD GVCCIDEFDKM AD+ AIHE MEQQTISI
Sbjct: 234 SGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISI 293
Query: 646 AKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKI 705
AKAGI TLNAR SILAAANP GRYN + +L N+ + A ++SRFDL ++I D +
Sbjct: 294 AKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDN 353
Query: 706 DTELASHI--VDLHMKRDSAINPPFSAEQLSRYINYAKTFKPVMTKEARDYLVKRYTELR 763
D LA HI V H ++ + P + + RYI + +P++ + DY+ Y E+R
Sbjct: 354 DLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMR 413
Query: 764 KDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
++ SK + + R L +++RLS A+AR VD + V EA L+ S
Sbjct: 414 RE--AWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
>CE09874 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 730
Score = 296 bits (758), Expect = 1e-79
Identities = 197/593 (33%), Positives = 307/593 (51%), Gaps = 100/593 (16%)
Query: 238 PDQVERVLQISFLNLPTVHR--IRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCEL 295
P Q+ + ++ F H +R+I+A +IG L+++ G V R +E++P + ++TC+
Sbjct: 140 PPQLLQRFEVYFTTDDAAHETCVRNIKATEIGHLVSMKGVVIRATEVKPCVEVMTYTCDT 199
Query: 296 CRAVIDNVEQVFKYTEPTSCPNPTC---ENQSFWSLNVNRSKFLDWQKVRIQENSNEIPS 352
C A + + ++T P +CPN C + + + SKF+ +Q+++IQE S ++P
Sbjct: 200 CAAEVYQPVKGMQFTPPVNCPNKECVEAKANGRLHMQLRGSKFVKFQELKIQELSEQVPV 259
Query: 353 GSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTT 412
GS+PRT+ + + G+ + G+ V VS + LP +++ P T
Sbjct: 260 GSIPRTMTVHVYGEMTRKCNTGN----------VVHVSGVFLPIMQSGFRP--------T 301
Query: 413 EGLNSGISGLKSLGVRDLTYKISFLACHVEN---VGTSFNGSRINEEDADKTSKFDYINL 469
GL V D ++L H N +FNG + E + +
Sbjct: 302 GGL-----------VAD-----TYLEAHYINNLDDNPTFNGVQSAELE---------VLR 336
Query: 470 RNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGI 529
R NYE A + IAP +FGH +KK +
Sbjct: 337 RKGDNYETLAAS---------------------------------IAPEIFGHVDVKKCL 363
Query: 530 LLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAG 589
L+ ++ G + + G+K+RG IN+ ++GDP +KSQ L YV +PR+ YT+G+ SS G
Sbjct: 364 LMALVGG-NDNSSNGMKIRGCINVLMMGDPGVAKSQLLGYVNRLAPRSQYTTGRGSSGVG 422
Query: 590 LTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAG 649
LTAAV+KD G+ ++E GAL+LAD G+CCIDEFDKM D+ AIHE MEQQTISIAKAG
Sbjct: 423 LTAAVMKDPVTGEMSLEGGALVLADGGICCIDEFDKMMDHDRTAIHEVMEQQTISIAKAG 482
Query: 650 IHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTEL 709
I TLNART+I+AAANP GRYN ++ N+++ A ++SRFDL ++ D + + D L
Sbjct: 483 IMTTLNARTAIIAAANPAYGRYNPNRSIEQNVDLPAALLSRFDLILLMQDKADRENDKIL 542
Query: 710 ASHIVDLHM--------KRDSAINPPFSAEQLSRYINYAKTFKPVMTKEARDYLVKRYTE 761
A HI +H K+D S E L YI+ KT+ P + R+ +V+ Y E
Sbjct: 543 AEHITYVHQHGCHPNREKKDL-----ISLETLREYISLCKTYTPTVDPALRERIVEAYVE 597
Query: 762 LRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLR 814
+R+D YS ++ R + ++R++ A A+ + S V EA L++
Sbjct: 598 MRRD--ARYSSDPTFVSPRMILGIVRMATARAKLRLSTIVDESDVEEALRLMQ 648
>YLR274w [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 775
Score = 295 bits (755), Expect = 2e-79
Identities = 201/604 (33%), Positives = 304/604 (50%), Gaps = 103/604 (17%)
Query: 258 IRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCR----AVIDNVEQVFKYTE-- 311
+RD+ + + ++ +SG + TS + S C CR I+N + T
Sbjct: 148 LRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNTVSL 207
Query: 312 PTSCPNPTCENQSFWSLNVN--------------------RSKFLDWQKVRIQENSNEIP 351
P SC + T E++S + N SKF+D Q +++QE +P
Sbjct: 208 PRSCLS-TIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPELVP 266
Query: 352 SGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRT 411
G MPR L + + PG R +G + + G
Sbjct: 267 VGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAG------------------ 308
Query: 412 TEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRN 471
G + G +G + +R KI + VE TS
Sbjct: 309 -SGRSGGGNGGSGVAIRTPYIKILGIQSDVE------------------TSSI------- 342
Query: 472 YQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILL 531
+ + M E ++E FL ++ ++ +Y+ L SIAP++FG+E IKK I+
Sbjct: 343 WNSVTMFTEEEEEEFL------------QLSRNPKLYEILTNSIAPSIFGNEDIKKAIVC 390
Query: 532 QMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLT 591
++ G K +G++LRGDIN+ ++GDP T+KSQ LK+V SP AVYTSGK SSAAGLT
Sbjct: 391 LLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLT 450
Query: 592 AAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIH 651
A+V +D +F +E GA++LAD GV CIDEFDKM D+VAIHEAMEQQTISIAKAGI
Sbjct: 451 ASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGIT 510
Query: 652 ATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELAS 711
LN+RTS+LAAANP+ GRY+ + N++ I+SRFD+ F++ DD NE+ D +A+
Sbjct: 511 TVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIAN 570
Query: 712 HIVDLHMKRDSAI-------NPPFSAEQLSRYINYAK-TFKPVMTKEARDYLVKRYTELR 763
H++++H +A+ S E++ RYI Y + P ++ +A + L + +R
Sbjct: 571 HVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIR 630
Query: 764 K----DDAQGYSKSSYRITVRQLESLIRLSEAIARANC--------VDEIVPSFVAEAYD 811
K ++ + +SS IT+RQLE++IR++E++A+ VDE + F A D
Sbjct: 631 KQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMD 690
Query: 812 LLRQ 815
Q
Sbjct: 691 AASQ 694
>Hs19923727 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 840
Score = 295 bits (754), Expect = 3e-79
Identities = 202/623 (32%), Positives = 301/623 (47%), Gaps = 116/623 (18%)
Query: 248 SFLNLPTVH----------RIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCR 297
+ +N+P +H +++++RAN G +A+ GTV R S I+P K +F C C
Sbjct: 187 TMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACG 246
Query: 298 AVIDNVEQVFKYTEPTSCPNPTCENQSFWSLNVNR-SKFLDWQKVRIQE--NSNEIPSGS 354
+ KY+ PT CP P C +SF +L + + +DWQ ++IQE + ++ +G
Sbjct: 247 EIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGR 306
Query: 355 MPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEG 414
+PRT++ L D V+ PGD G VK S+ +
Sbjct: 307 IPRTIECELVHDLVDSCVPGDTVTITGI--------------VKVSNAEE---------- 342
Query: 415 LNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRI-NEEDADKTSKFDYINLRNYQ 473
G R+ K FL N ++ G + + ED K +L+
Sbjct: 343 -----------GSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLK--- 388
Query: 474 NYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQM 533
++ ++E+ +EN++ +V S+ P +FGHE +K G+ L +
Sbjct: 389 --------------------DLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALAL 428
Query: 534 LSGVHKTTVEG--IKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLT 591
G K + I +RGD +I +VGDP KSQ L+ CN +PR VY G ++ +GLT
Sbjct: 429 FGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLT 488
Query: 592 AAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIH 651
+ KD GDF +EAGAL+L D G+C IDEFDKM Q A+ EAMEQQ+IS+AKAG+
Sbjct: 489 VTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVV 547
Query: 652 ATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELAS 711
+L ARTSI+AAANPVGG YN+ T+ NL M + ++SRFDL F++LD NE D L+
Sbjct: 548 CSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSE 607
Query: 712 HIVDLHMKRDSAIN-------------------------------------PPFSAEQLS 734
H++ + + I+ P + L
Sbjct: 608 HVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLR 667
Query: 735 RYINYAKTF-KPVMTKEARDYLVKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIA 793
+YI YA+ + P ++ EA L Y ELRK Q +S IT RQLESLIRL+EA A
Sbjct: 668 KYIGYARQYVYPRLSTEAARVLQDFYLELRK---QSQRLNSSPITTRQLESLIRLTEARA 724
Query: 794 RANCVDEIVPSFVAEAYDLLRQS 816
R +E + ++++ S
Sbjct: 725 RLELREEATKEDAEDIVEIMKYS 747
>7299365 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 733
Score = 290 bits (742), Expect = 8e-78
Identities = 205/630 (32%), Positives = 310/630 (48%), Gaps = 82/630 (13%)
Query: 230 APSTIATNPDQVERVLQISFLNLPTVH--RIRDIRANKIGSLMAISGTVTRTSEIRPELY 287
A A P+ E + I L + IR ++++ + L+ I+G + S I +
Sbjct: 102 ADEITAPRPEHEEHMHDIQILLSSNANPTNIRQLKSDCVSKLVKIAGIIVAASGISAKAT 161
Query: 288 KASFTCELCRAVIDNVEQ---VFKYTEPTSCPN-----PTCENQSFWSLNVNRSKFLDWQ 339
+ S C C VI N++ + Y P C P C F+ + ++ K +D+Q
Sbjct: 162 RMSIQCLSCSTVIPNLKVNPGLEGYALPRKCNTEQAGRPKCPLDPFFIMP-DKCKCVDFQ 220
Query: 340 KVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKA 399
+++QE + +P G +PR L + ER PG+R G + + ++G P +
Sbjct: 221 TLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNRVLIQG----IYSIRKVGKPSRR- 275
Query: 400 SSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDAD 459
+G + G+++ +R + G ++ E A
Sbjct: 276 -------------DGREKAVVGVRAPYMRVV-------------------GITVDSEGAG 303
Query: 460 KTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAV 519
S++ I SDE + M +IY++L +S+AP++
Sbjct: 304 AISRYSNIT-----------------------SDEEEHFRRMAASGDIYERLSQSLAPSI 340
Query: 520 FGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVY 579
FG IKK I + G K +G+ RGDIN+ ++GDP T+KSQ LK+V +P AVY
Sbjct: 341 FGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVY 400
Query: 580 TSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAME 639
TSGK SSAAGLTA+V+KD + +F +E GA++LAD GV CIDEFDKM D+VAIHEAME
Sbjct: 401 TSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAME 460
Query: 640 QQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILD 699
QQTISIAKAGI TLN+R S+LAAAN + GR++ N++ I+SRFD+ F++ D
Sbjct: 461 QQTISIAKAGITTTLNSRCSVLAAANSIFGRWD-DTKGEENIDFMPTILSRFDMIFIVKD 519
Query: 700 DCNEKIDTELASHIVDLHMKRD-SAINPP----FSAEQLSRYINYAKTF-KPVMTKEARD 753
+E D LA HI+++H+ + SA + P S +YI+Y +T P +++ A +
Sbjct: 520 IHDESRDITLAKHIINVHLSSNKSAPSEPAEGEISLSTFKKYIHYCRTHCGPRLSEAAGE 579
Query: 754 YLVKRYTELRKDDAQGYSKSSYR----ITVRQLESLIRLSEAIARANCVDEIVPSFVAEA 809
L RY +R Q S R ITVRQLE++IR+SE++A+ V EA
Sbjct: 580 KLKSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNEA 639
Query: 810 YDLLRQSXXXXXXXXXXXXXXXNSPEESTE 839
L + S + EE E
Sbjct: 640 LRLFQVSTLDAAMTGSLAGAEGFTTEEDQE 669
>Hs11418031 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 734
Score = 288 bits (737), Expect = 3e-77
Identities = 193/594 (32%), Positives = 306/594 (51%), Gaps = 80/594 (13%)
Query: 239 DQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRA 298
++V + +Q+ + + IR ++++ + L+ I G + S +R + + S C CR
Sbjct: 118 EEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRN 177
Query: 299 VIDNVEQ---VFKYTEPTSCPN-----PTCENQSFWSLNVNRSKFLDWQKVRIQENSNEI 350
+ N+ + Y P C P C ++ + ++ K +D+Q +++QE + +
Sbjct: 178 TLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMP-DKCKCVDFQTLKLQELPDAV 236
Query: 351 PSGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISR 410
P G MPR + + ++ PG+R V+ +G+ +K SRG R
Sbjct: 237 PHGEMPRHMQLYCDRYLCDKVVPGNR------------VTIMGIYSIKKFGLTTSRGRDR 284
Query: 411 TTEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLR 470
G+ S S ++ LG++ T + G SF G+ +E+
Sbjct: 285 VGVGIRS--SYIRVLGIQVDT----------DGSGRSFAGAVSPQEE------------- 319
Query: 471 NYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGIL 530
E + + N+Y+ + KSIAP++FG +KK I
Sbjct: 320 -------------------------EEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIA 354
Query: 531 LQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGL 590
+ G K +G+ RGDIN+ ++GDP T+KSQ LK+V SP VYTSGK SSAAGL
Sbjct: 355 CLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGL 414
Query: 591 TAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGI 650
TA+V++D +F +E GA++LAD GV CIDEFDKM D+VAIHEAMEQQTISIAKAGI
Sbjct: 415 TASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGI 474
Query: 651 HATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELA 710
TLN+R S+LAAAN V GR++ + N++ I+SRFD+ F++ D+ NE+ D LA
Sbjct: 475 TTTLNSRCSVLAAANSVFGRWD-ETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLA 533
Query: 711 SHIVDLH---MKRDSAINPPFSAEQLSRYINYAKT-FKPVMTKEARDYLVKRY----TEL 762
H++ LH + + A+ +L ++I Y + P ++ EA + L RY +
Sbjct: 534 KHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGA 593
Query: 763 RKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
R+ + +SS ITVRQLE+++R++EA+++ + V EA L + S
Sbjct: 594 RQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 647
>At3g09660 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 777
Score = 288 bits (737), Expect = 3e-77
Identities = 189/581 (32%), Positives = 308/581 (52%), Gaps = 71/581 (12%)
Query: 258 IRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVEQVFKYTEPTSCPN 317
++++RA IG L+ + GTV + S ++P + + +F C C+ I K++ P C +
Sbjct: 145 LKNLRAAYIGKLVTVHGTVVKVSTVKPLVTQMAFDCGKCKTGITREFTDGKFSPPLKCDS 204
Query: 318 PTCENQSFWSLNVNRSKFLDWQKVRIQE--NSNEIPSGSMPRTLDIILRGDCVERAKPGD 375
C++++F + + ++ +D+QK+R+QE + G +PRT++ L D V+ PGD
Sbjct: 205 HGCKSKTFTPIR-SSAQTIDFQKIRVQELQKPEDHEEGRVPRTVECELMEDLVDICIPGD 263
Query: 376 RCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKIS 435
G V+ + +G G S K+ G Y +
Sbjct: 264 VVTVTGIIGVINNYMDIG-----------------------GGKSKTKNQGF----YYLF 296
Query: 436 FLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSDEI 495
A V+N T + N ED+ +++ A+ ++ D + I
Sbjct: 297 IEAVSVKN--TKRQSAFENSEDSSSSAQ--------------TADVGDLYSFSQRDLEFI 340
Query: 496 NELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKL--RGDINI 553
+ KE + + +++ S+ P+++GHE +K GI L + GV K +++ K+ RGDI++
Sbjct: 341 VKFKEEYGSDT-FRRILHSVCPSIYGHEIVKAGITLSLFGGVRKHSMDRNKVPVRGDIHV 399
Query: 554 CIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLA 613
IVGDP KSQ L+ SPR +Y G A++ AGLT AVVKD D+ EAGA++LA
Sbjct: 400 IIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTRAGLTVAVVKDSMTNDYAFEAGAMVLA 459
Query: 614 DNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNR 673
D G+CCIDEFDKM Q A+ EAMEQQ +S+AKAG+ A+L+ARTS++AAANPVGG YNR
Sbjct: 460 DGGLCCIDEFDKMTTEHQ-ALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPVGGHYNR 518
Query: 674 KLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDSAI--------- 724
T+ NL MSA ++SRFDL F++LD +E +D +++ HI+ H
Sbjct: 519 AKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMSHHRMLGMQTCMQKGILYF 578
Query: 725 -NPPFSAEQLSRYI--------NYAKTFKPVMTKEARDYLVKRYTELRKDDAQGYSKSSY 775
+ ++ +++ ++ N +M+K+A + + K Y +LR + S S
Sbjct: 579 QDCGWTLRKMTTFLRFLANCLGNIFPMHGILMSKDAGEIIQKFYLKLRDHNT---SADST 635
Query: 776 RITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
IT RQLESL+RL++A AR + +EI + +++++S
Sbjct: 636 PITARQLESLVRLAQARARVDLREEITVQDAMDVVEIMKES 676
>Hs6981192 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 733
Score = 285 bits (730), Expect = 2e-76
Identities = 193/593 (32%), Positives = 303/593 (50%), Gaps = 79/593 (13%)
Query: 239 DQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRA 298
++V + +Q+ + + IR ++++ + L+ I G + S +R + + S C CR
Sbjct: 118 EEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRN 177
Query: 299 VIDNVEQ---VFKYTEPTSCPN-----PTCENQSFWSLNVNRSKFLDWQKVRIQENSNEI 350
+ N+ + Y P C P C ++ + ++ K +D+Q +++QE + +
Sbjct: 178 TLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMP-DKCKCVDFQTLKLQELPDAV 236
Query: 351 PSGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISR 410
P G MPR + + ++ PG+R V+ +G+ +K SRG R
Sbjct: 237 PHGEMPRHMQLYCDRYLCDKVVPGNR------------VTIMGIYSIKKFGLTTSRGRDR 284
Query: 411 TTEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLR 470
G+ S S ++ LG++ T + G SF G+ +E+
Sbjct: 285 VGVGIRS--SYIRVLGIQVDT----------DGSGRSFAGAVSPQEE------------- 319
Query: 471 NYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGIL 530
E + + N+Y+ + KSIAP++FG +KK I
Sbjct: 320 -------------------------EEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIA 354
Query: 531 LQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGL 590
+ G K +G+ RGDIN+ ++GDP T+KSQ LK+V SP VYTSGK SSAAGL
Sbjct: 355 CLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGL 414
Query: 591 TAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGI 650
TA+V++D +F +E GA++LAD GV CIDEFDKM D+VAIHEAMEQQTISIAKAGI
Sbjct: 415 TASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGI 474
Query: 651 HATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELA 710
TLN+R S+LAAAN V GR++ + N++ I+SRFD+ F++ D+ NE D LA
Sbjct: 475 TTTLNSRCSVLAAANSVFGRWD-ETKGEDNIDFMPTILSRFDMIFIVKDEHNEVRDVMLA 533
Query: 711 SHIVDLH---MKRDSAINPPFSAEQLSRYINYAKT-FKPVMTKEARDYLVKRYTELRKDD 766
H++ LH + + A+ +L ++I Y + P ++ EA + L RY +R
Sbjct: 534 KHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRTGP 593
Query: 767 AQ---GYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
+ SS ITVRQLE+++R++EA+++ + V EA L + S
Sbjct: 594 VSTRGTVTASSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 646
>SPAC3F10.01 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 649
Score = 284 bits (726), Expect = 6e-76
Identities = 190/558 (34%), Positives = 290/558 (51%), Gaps = 92/558 (16%)
Query: 258 IRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAV-IDNVEQVFKYTE-PTSC 315
IR++ A+ I L+ + G + S + C CRA I + F + P C
Sbjct: 61 IRNLTASHISKLVRVPGIIIGASTLSCRATALHLVCRNCRATRILQISGGFSGVQLPRVC 120
Query: 316 PNPTCENQSF------WSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGD--C 367
P + + + ++ ++S F+D Q +++QE + +P G +PR I+L D
Sbjct: 121 EAPVLDGEKKDCPMDPFIIDHSKSTFIDQQVLKLQEAPDMVPVGELPR--HILLNADRYL 178
Query: 368 VERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGV 427
+ PG RC G + + S VKAS
Sbjct: 179 TNQITPGTRCVITGIFSIFQNKS------VKASG-------------------------- 206
Query: 428 RDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQEIFL 487
A + N G +++ D K++ + +E ++E FL
Sbjct: 207 ----------AVAIRNPYIRVVGIQMDSNDGSKSTP-------------LFSEEEEEEFL 243
Query: 488 TRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKL 547
E+ + N+YD + SI+PA++G+ IKK I + SG K +G++L
Sbjct: 244 ------------EISRTPNLYDIISNSISPAIYGNVDIKKAIACLLFSGSKKILPDGMRL 291
Query: 548 RGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEA 607
RGDIN+ ++GDP T+KSQFLK+V +P AVYTSGK SSAAGLTA++ +D +F +E
Sbjct: 292 RGDINVLLLGDPGTAKSQFLKFVERLAPIAVYTSGKGSSAAGLTASIQRDSVTREFYLEG 351
Query: 608 GALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPV 667
GA++LAD G+ CIDEFDKM D+VAIHEAMEQQTISIAKAGI LN+RTS+LAAANP+
Sbjct: 352 GAMVLADGGIVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTILNSRTSVLAAANPI 411
Query: 668 GGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDSAINP- 726
GRY+ T N++ + I+SRFD+ F++ D+ +E D +A H+++LH +
Sbjct: 412 FGRYDDMKTPGENIDFQSTILSRFDMIFIVKDEHDETKDRNIARHVINLHTNLQESSETL 471
Query: 727 -----PFSAEQLSRYINYAK-TFKPVMTKEARDYLVKRYTELRK----DDAQGYSKSSYR 776
PF ++ RYINY + P + EA + L ++ +RK + S+S+
Sbjct: 472 AIGEIPF--DKFRRYINYCRHKCAPNLDAEAAEKLSSQFVAIRKRVHQSEQDSNSRSTIP 529
Query: 777 ITVRQLESLIRLSEAIAR 794
ITVRQLE++IR++E++A+
Sbjct: 530 ITVRQLEAIIRITESLAK 547
>At2g07690 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 727
Score = 283 bits (723), Expect = 1e-75
Identities = 151/332 (45%), Positives = 215/332 (64%), Gaps = 8/332 (2%)
Query: 493 DEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDIN 552
DE E K+ +++Y + IAP++FGHE +K+ + G K+ +G+KLRGDIN
Sbjct: 311 DEEEEFKKFADSQDVYKNICTKIAPSIFGHEDVKRAAACLLFGGSRKSLPDGVKLRGDIN 370
Query: 553 ICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALML 612
+ ++GDPST+KSQFLK+V +P AVYTSGK SSAAGLTA+V++D +F +E GA++L
Sbjct: 371 VLLLGDPSTAKSQFLKFVEKTAPIAVYTSGKGSSAAGLTASVIRDSSTREFYLEGGAMVL 430
Query: 613 ADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYN 672
AD GV CIDEFDKM D+VAIHEAMEQQTISIAKAGI LN+RTS+LAAANP GRY+
Sbjct: 431 ADGGVVCIDEFDKMRPEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPPSGRYD 490
Query: 673 RKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDSAINPPFSAEQ 732
T + N+++ I+SRFDL F++ D D E+ASHI+ +H + + +++
Sbjct: 491 DLKTAQDNIDLQTTILSRFDLIFIVKDIRKYSQDKEIASHIIRVHASANKFSDENTDSKE 550
Query: 733 ---LSRYINYAKT-FKPVMTKEARDYLVKRYTELRKDDAQGYSKSS----YRITVRQLES 784
L RYI Y + P ++K+A + L ++Y +R D + ++ ITVRQLE+
Sbjct: 551 DNWLKRYIQYCRARCHPRLSKDAAENLQRKYVTIRMDMKRRAHETGEAAPIPITVRQLEA 610
Query: 785 LIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
++RLSE++A+ E P V +A+ L S
Sbjct: 611 IVRLSESLAKMRLSHEATPDDVDKAFKLFDTS 642
>7290573 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 819
Score = 281 bits (718), Expect = 5e-75
Identities = 194/611 (31%), Positives = 297/611 (47%), Gaps = 132/611 (21%)
Query: 259 RDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVEQVFKYTE------- 311
R + + +G+++ + G VT+ S IRP++ ++ C R V++ KYT+
Sbjct: 111 RSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMER-----KYTDLTSFEAV 165
Query: 312 PTSCPNPTC-ENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVER 370
P+ PT E+ + S + D Q + IQE + P+G +PR++DI+ D V
Sbjct: 166 PSGAAYPTKDEDGNLLETEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLV-- 223
Query: 371 AKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGVRDL 430
DRCK PG + R + G SG
Sbjct: 224 ----DRCK----------------PGDRVQIVGSYRCLPGKRGGYTSG------------ 251
Query: 431 TYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQEIFLTRL 490
T++ LA ++ + K S D +
Sbjct: 252 TFRTVLLANNISLLS--------------KESNLD------------------------I 273
Query: 491 DSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGD 550
++I K++ K+ +I++ L KS+AP++ GH +K+ IL +L GV K G +LRGD
Sbjct: 274 SREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGD 333
Query: 551 INICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGAL 610
IN+ ++GDPS +KSQ L+YV N +PRA+ T+G+ SS GLTAAV D+E G+ +EAGA+
Sbjct: 334 INVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAM 393
Query: 611 MLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGR 670
+LAD GV CIDEFDKM D+ AIHE MEQ ++I+KAGIHA+LNAR S+LAAANPV GR
Sbjct: 394 VLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGR 453
Query: 671 YNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHM------------ 718
Y++ T N+ + ++SRFDL FV+LD + +D ++ H+V +H
Sbjct: 454 YDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEADGEPL 513
Query: 719 ------------------KRDSAINPPF----------------SAEQLSRYINYAKTFK 744
K+D+ + + S E + +YI+ AK K
Sbjct: 514 SMGSSYADSLSFVSSSEEKKDTEVYEKYDALLHGKSRQRHEKILSVEFMRKYIHIAKCMK 573
Query: 745 PVMTKEARDYLVKRYTELRKDDA-QGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVP 803
P + ++A + + Y+ LR +A + + IT R LE+LIRLS A ARA +
Sbjct: 574 PKLGEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETLIRLSTAHARARMSKSVTI 633
Query: 804 SFVAEAYDLLR 814
A +L++
Sbjct: 634 DDAHAAIELVQ 644
>CE19038 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 881
Score = 280 bits (715), Expect = 1e-74
Identities = 185/572 (32%), Positives = 293/572 (50%), Gaps = 97/572 (16%)
Query: 245 LQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDN-V 303
+++ LP IR +R + L+ +G VT S I P+L + C C ++ V
Sbjct: 257 IKVRISQLPVEEDIRMLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLGPFV 316
Query: 304 EQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIIL 363
+Q + PT CP+ C+ + + LNV + + ++Q++ +QE+ N++ +G +PR+ D+IL
Sbjct: 317 QQNDEEVRPTICPS--CQGKGPFELNVENTVYHNYQRITMQESPNKVAAGRLPRSKDVIL 374
Query: 364 RGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLK 423
GD + KP G EI V V G
Sbjct: 375 LGDLCDSCKP-------GDEIEVTGVYTNNFDG--------------------------- 400
Query: 424 SLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQ 483
L YK F + T + + I +D +MA++
Sbjct: 401 -----SLNYKQGFPVFN-----TLIHANHITNKD------------------KMASD--- 429
Query: 484 EIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVE 543
+L ++I ++E+ +D NI ++ SIAP+++GH+ +K+ I L + G K
Sbjct: 430 -----QLTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRGEAKNPGA 484
Query: 544 GIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDF 603
+LRGDIN+ + GDP T+KSQFL+Y + +PR+V T+G+ +SA GLTA V + ++
Sbjct: 485 KHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQRHPVTREW 544
Query: 604 TIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAA 663
T+EAGA++LAD GVC IDEFDKM D+ +IHEAMEQQ+ISI+KAGI +L+AR +++AA
Sbjct: 545 TLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHARCTVIAA 604
Query: 664 ANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH------ 717
+NP+GGRYN T N++++ PI+SRFD+ VI D + D LA +V H
Sbjct: 605 SNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGNHRTHHPD 664
Query: 718 ----MKRDSAINPPFSAEQ----------LSRYINYAK-TFKPVMTKEARDYLVKRYTEL 762
+K + E+ L +YI YA+ P + ++ + + ++
Sbjct: 665 AKKIVKEGDELEEDQMDERTGVRLIPQDLLRKYIIYAREKCHPTLPEQHSEKFSNIFAQM 724
Query: 763 RKDDAQGYSKSSYRITVRQLESLIRLSEAIAR 794
RK + + S ITVR +ES+IRLSEA A+
Sbjct: 725 RK---ESMATGSVAITVRHVESMIRLSEAHAK 753
>YEL032w [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 971
Score = 277 bits (709), Expect = 5e-74
Identities = 170/464 (36%), Positives = 248/464 (52%), Gaps = 68/464 (14%)
Query: 259 RDIRANKIGSLMAISGTVTRTSEIRPELYK----ASFTCELCRAVIDNVEQVFKYTEPTS 314
R + A + L+++ G VT+TS +RP+L + A+ T + PT
Sbjct: 169 RTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTP 228
Query: 315 CPNPTCENQ-SFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKP 373
PT + + + + S F+D Q++ +QE P+G +PR++D+IL D V++ KP
Sbjct: 229 AIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKP 288
Query: 374 GDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYK 433
GDR +G LG G+ S++ + + G K+L + + Y
Sbjct: 289 GDRVNVVGV------FKSLGAGGMNQSNS--------------NTLIGFKTLILGNTVYP 328
Query: 434 ISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSD 493
+ H + G + LT D
Sbjct: 329 L-----HARSTGVAARQ-----------------------------------MLTDFDIR 348
Query: 494 EINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINI 553
IN+L K ++I+D L +S+AP+++GH+ IKK ILL ++ GV K G LRGDINI
Sbjct: 349 NINKLS---KKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINI 405
Query: 554 CIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLA 613
+VGDPST+KSQ L++V N + A+ T+G+ SS GLTAAV D E G+ +EAGA++LA
Sbjct: 406 LMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLA 465
Query: 614 DNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNR 673
D GV CIDEFDKM D+VAIHE MEQQT++IAKAGIH TLNAR S++AAANPV G+Y+
Sbjct: 466 DRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDV 525
Query: 674 KLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH 717
N+ + ++SRFDL FV+ DD NE D ++ H++ H
Sbjct: 526 NRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTH 569
>SPCC1682.02c [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 879
Score = 277 bits (709), Expect = 5e-74
Identities = 192/624 (30%), Positives = 292/624 (46%), Gaps = 142/624 (22%)
Query: 259 RDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVEQVFKYTEPT----- 313
R +RA + ++++ G VTR S +RP++ K+ CE + +Y + T
Sbjct: 118 RTLRAMHLNKMISLEGIVTRCSFVRPKVIKSVHYCEATKR-----HHFKQYADATMNGGL 172
Query: 314 ---SCPNPTC-ENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVE 369
S PT EN + S+ S F D Q + +QE P G +PR++DI+L D V+
Sbjct: 173 SFQSTVYPTQDENGNPLSIEFGFSTFRDHQSISLQEMPERAPPGQLPRSIDILLDDDLVD 232
Query: 370 RAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGVRD 429
K PG + + R + T G S
Sbjct: 233 TVK----------------------PGDRVNIVGQYRSMGSKTSGNTSA----------- 259
Query: 430 LTYKISFLACHVENVGT-----SFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQE 484
T++ LA +V +G + G ++ DAD
Sbjct: 260 -TFRTVLLANNVVLLGNKPGLGNVGGGALDITDAD------------------------- 293
Query: 485 IFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEG 544
I + ++ + +N+++ L S+AP+++G+E +K+ ILL +L G K G
Sbjct: 294 ----------IRNINKLARKKNVFELLSTSLAPSIYGYEYVKQAILLLLLGGTEKNLTNG 343
Query: 545 IKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFT 604
+RGDINI +VGDPST+KSQ L++V N +P A+ T+G+ SS GLTAAV D+E G+
Sbjct: 344 THIRGDINILMVGDPSTAKSQLLRFVLNTAPLAIATTGRGSSGVGLTAAVTTDKETGERR 403
Query: 605 IEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAA 664
+EAGA++LAD GV CIDEFDKM D+VAIHE MEQQT++IAKAGIH +LNAR S++AAA
Sbjct: 404 LEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVIAAA 463
Query: 665 NPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDSAI 724
NP+ G+Y+ + N+ + ++SRFDL F++ DD ++K D L+ H++ +H +
Sbjct: 464 NPIYGQYDIRKDPHQNIALPDSMLSRFDLLFIVTDDIDDKKDRALSEHVLRMHRYLPPGV 523
Query: 725 NPPFSA-EQLSRYINYA---------------------KTFKPVMTKEAR---------- 752
P + L+ +N +TF ++ AR
Sbjct: 524 EPGTPVRDSLNSVLNVGATNAAGVSTENVEQEVETPVWETFSSLLHANARTKKKELLNIN 583
Query: 753 ----------------------DYLVKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSE 790
+Y+ Y LR DD QG + + +T R LE+LIRLS
Sbjct: 584 FVRKYIQYAKSRIHPILNQATAEYITNIYCGLRNDDLQGNQRRTSPLTARTLETLIRLST 643
Query: 791 AIARANCVDEIVPSFVAEAYDLLR 814
A A+A + A +LR
Sbjct: 644 AHAKARLSSVVEVKDAKAAEKILR 667
>SPBC4.04c [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 830
Score = 276 bits (706), Expect = 1e-73
Identities = 150/369 (40%), Positives = 229/369 (61%), Gaps = 23/369 (6%)
Query: 467 INLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIK 526
I + + + TD + L+RL DE E++ + K +I+++++ S+AP+++GH +IK
Sbjct: 444 IEANHISQLDGSGNTDDDFSLSRLTDDEEREIRALAKSPDIHNRIIASMAPSIYGHRSIK 503
Query: 527 KGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASS 586
I + GV K K+RGDIN+ ++GDP T+KSQFLKYV + RAV+ +G+ +S
Sbjct: 504 TAIAAALFGGVPKNINGKHKIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFATGQGAS 563
Query: 587 AAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIA 646
A GLTA+V KD ++T+E GAL+LAD GVC IDEFDKM+ D+ +IHEAMEQQ+ISI+
Sbjct: 564 AVGLTASVRKDPITNEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISIS 623
Query: 647 KAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKID 706
KAGI TL AR +I+AAANP+GGRYN + N+ ++ PI+SRFD+ V+ D N +ID
Sbjct: 624 KAGIVTTLQARCTIIAAANPIGGRYNTTIPFNQNVELTEPILSRFDILQVVKDTVNPEID 683
Query: 707 TELASHIVDLHMKRDSAINP-----------------PFSAEQLSRYINYA--KTFKPVM 747
+LA+ +V H++ A +P P + L +YI++A K F P +
Sbjct: 684 EQLANFVVSSHIRSHPAFDPNMDVLKKVPTETGIDAKPIPQDLLRKYIHFAREKVF-PRL 742
Query: 748 TKEARDYLVKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVA 807
+ + + + Y+++R+ + + SY ITVR LES IRLSEA A+ + + PS +
Sbjct: 743 QQMDEEKISRLYSDMRR---ESLATGSYPITVRHLESAIRLSEAFAKMQLSEFVRPSHID 799
Query: 808 EAYDLLRQS 816
+A ++ S
Sbjct: 800 KAIQVIIDS 808
Score = 82.4 bits (202), Expect = 3e-15
Identities = 47/153 (30%), Positives = 81/153 (52%), Gaps = 5/153 (3%)
Query: 232 STIATNPD--QVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKA 289
+T+ PD ++ + + NLPT +RD+R + + L+ +SG VTR + + P+L
Sbjct: 271 ATLLHYPDYERIHSDIHVRITNLPTCFTLRDLRQSHLNCLVRVSGVVTRRTGLFPQLKYI 330
Query: 290 SFTCELCRAVIDNVEQVFKYTEPTS-CPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSN 348
FTC C A + Q S C N C ++ + +N R+ + ++Q++ +QE+
Sbjct: 331 RFTCTKCGATLGPFFQDSSVEVKISFCHN--CSSRGPFVINSERTVYNNYQRITLQESPG 388
Query: 349 EIPSGSMPRTLDIILRGDCVERAKPGDRCKFIG 381
+PSG +PR ++IL D V+ AKPG+ G
Sbjct: 389 TVPSGRLPRHREVILLADLVDVAKPGEEIDVTG 421
>CE03558 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 759
Score = 274 bits (700), Expect = 6e-73
Identities = 192/602 (31%), Positives = 295/602 (48%), Gaps = 110/602 (18%)
Query: 258 IRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVE---QVFKYTEPTS 314
+R +++ ++ ++ ISG + +++R + K + C C+ I +V + + P +
Sbjct: 137 LRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKHTIPDVSIKPGLEGFALPRT 196
Query: 315 CPNPT------CENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCV 368
C P C + L ++ + +D+Q +++QEN ++P G MPR L +
Sbjct: 197 CAAPQQGQMQRCPIDPYIMLP-DKCECVDYQTLKLQENPEDVPHGEMPRHLQLFTERYLT 255
Query: 369 ERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSL-GV 427
++ PG+R +G + + + G G KSL G+
Sbjct: 256 DKVVPGNRVTIVGVYSIKKLIQKKG---------------------------GDKSLQGI 288
Query: 428 RDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQNYEMAAETDQEIFL 487
R T + L H+E G R N
Sbjct: 289 R--TPYLRVLGIHMETSGPG----RTN--------------------------------F 310
Query: 488 TRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKL 547
T +E K + + ++ Y+ + KSIAP+++G IKK I + G K +GI
Sbjct: 311 TTFTPEEERMFKTLAQRKDAYELIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITR 370
Query: 548 RGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEA 607
RGDIN+ ++GDP T+KSQ LK+V SP VYTSGK SSAAGLTA+V++D + F +E
Sbjct: 371 RGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASVIRDPQSRSFIMEG 430
Query: 608 GALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPV 667
GA++LAD GV CIDEFDKM D+VAIHEAMEQQTISIAKAGI TLN+R S+LAAAN V
Sbjct: 431 GAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSV 490
Query: 668 GGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHM------KRD 721
GR++ N++ I+SRFD+ +++ D + D LA H++++H+ +RD
Sbjct: 491 YGRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKERD 549
Query: 722 SAINPP------------------FSAEQLSRYINYAK-TFKPVMTKEARDYLVKRYTEL 762
A P + E L +++ YA+ P +T +A + LV Y ++
Sbjct: 550 IAGVPKTATTDSDGVMTMFDTDGFLTIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKM 609
Query: 763 RKD----DAQGYSKSSYR----ITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLR 814
R DA K ++ ITVRQLE+++R++E+IA+ V EA L R
Sbjct: 610 RNPVVNADAFKSGKKAHNSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRLFR 669
Query: 815 QS 816
S
Sbjct: 670 VS 671
>At5g46280 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 776
Score = 271 bits (692), Expect = 5e-72
Identities = 151/424 (35%), Positives = 234/424 (54%), Gaps = 40/424 (9%)
Query: 494 EINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINI 553
+++ +K + + ++ +D L +S+AP+++GH IKK ++L ML GV K G LRGDIN+
Sbjct: 272 DLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINM 331
Query: 554 CIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLA 613
+VGDPS +KSQ L+ + N +P A+ T+G+ SS GLTAAV D+E G+ +EAGA++LA
Sbjct: 332 MMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLA 391
Query: 614 DNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNR 673
D G+ CIDEFDKM+ D+VAIHE MEQQT++IAKAGIHA+LNAR S++AAANP+ G Y+R
Sbjct: 392 DKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDR 451
Query: 674 KLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH---------------- 717
LT N+ + ++SRFDL F++LD + ID+ ++ H++ +H
Sbjct: 452 SLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHRYKNDRGEAGPDGSLP 511
Query: 718 ----------------------MKRDSAINPPFSAEQLSRYINYAK-TFKPVMTKEARDY 754
KR + + + L +YI+YAK P +T EA +
Sbjct: 512 YAREDNAESEMFVKYNQTLHGKKKRGQTHDKTLTIKFLKKYIHYAKHRITPKLTDEASER 571
Query: 755 LVKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLR 814
+ + Y +LR + + + IT R LE++IRL+ A A+ E+ + A L+
Sbjct: 572 IAEAYADLRNAGSDTKTGGTLPITARTLETIIRLATAHAKMKLSSEVTKADAEAALKLMN 631
Query: 815 QSXXXXXXXXXXXXXXXNSPEESTEGEGTIPATQHFGETLDTQSQSPSQPLNADSETGGG 874
+ E E E T P+ + + + + + + N DSET
Sbjct: 632 FAIYHQELTEMDDREQEERQREQAEQERT-PSGRRGNQRRNNEDGAENDTANVDSETADP 690
Query: 875 PDVE 878
+V+
Sbjct: 691 MEVD 694
Score = 59.7 bits (143), Expect = 2e-08
Identities = 39/142 (27%), Positives = 69/142 (48%), Gaps = 3/142 (2%)
Query: 259 RDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVID-NVEQVFKYTE-PTSCP 316
R++ ++ IGS++ + G VT+ S +RP++ K+ C + + + + PT
Sbjct: 105 RELLSDFIGSMVCVEGIVTKCSLVRPKVVKSVHFCPSTGEFTNRDYRDITSHAGLPTGSV 164
Query: 317 NPTCENQ-SFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPGD 375
PT +++ + K+ D Q + IQE G +PR++D+I D V+ KPGD
Sbjct: 165 YPTRDDKGNLLVTEYGLCKYKDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGD 224
Query: 376 RCKFIGTEIVVPDVSQLGLPGV 397
R G +P S+ + GV
Sbjct: 225 RVSVFGIYKALPGKSKGSVNGV 246
>7299005 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 887
Score = 268 bits (686), Expect = 2e-71
Identities = 146/349 (41%), Positives = 223/349 (63%), Gaps = 17/349 (4%)
Query: 482 DQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTT 541
D + + L ++I ++++ KD I +++V S+AP+++GH+ IK+ + L + G K
Sbjct: 433 DSKQVVQSLTDEDIATIQKLSKDPRIVERVVASMAPSIYGHDYIKRALALALFGGESKNP 492
Query: 542 VEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGG 601
E K+RGDIN+ I GDP T+KSQFLKY +PRAV+T+G+ +SA GLTA V ++
Sbjct: 493 GEKHKVRGDINLLICGDPGTAKSQFLKYTEKVAPRAVFTTGQGASAVGLTAYVRRNPVSR 552
Query: 602 DFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSIL 661
++T+EAGAL+LAD GVC IDEFDKM+ D+ +IHEAMEQQ+ISI+KAGI +L AR +++
Sbjct: 553 EWTLEAGALVLADQGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVI 612
Query: 662 AAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRD 721
AAANP+GGRY+ +T N+N+S PI+SRFD+ V+ D+ + D +LA +V HMK
Sbjct: 613 AAANPIGGRYDPSMTFSENVNLSEPILSRFDVLCVVKDEFDPMQDQQLAKFVVHSHMKHH 672
Query: 722 SAINPPFSAEQ-------------LSRYINYAK-TFKPVMTKEARDYLVKRYTELRKDDA 767
+ E+ L +YI YAK +P +T D + K Y +LR+
Sbjct: 673 PSEEEQPELEEPQLKTVDEIPQDLLRQYIVYAKENIRPKLTNIDEDKIAKMYAQLRQ--- 729
Query: 768 QGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
+ ++ S ITVR +ES+IR+SEA AR + + ++ + V+ A ++ +S
Sbjct: 730 ESFATGSLPITVRHIESVIRMSEAHARMHLRENVMEADVSMAIRMMLES 778
Score = 79.7 bits (195), Expect = 2e-14
Identities = 41/144 (28%), Positives = 76/144 (52%), Gaps = 3/144 (2%)
Query: 239 DQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRA 298
++V + + LP + +R R + L+ G VT T+ + P+L + C C
Sbjct: 260 ERVTTEIHVRISELPLIEELRTFRKLHLNQLVRTLGVVTATTGVLPQLSVIKYDCVKCGY 319
Query: 299 VIDN-VEQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPR 357
V+ V+ +P SCP C++ +S+N+ ++ + ++QK+ +QE+ IP+G +PR
Sbjct: 320 VLGPFVQSQNTEIKPGSCPE--CQSTGPFSINMEQTLYRNYQKITLQESPGRIPAGRIPR 377
Query: 358 TLDIILRGDCVERAKPGDRCKFIG 381
+ D+IL D ++ KPGD + G
Sbjct: 378 SKDVILLADLCDQCKPGDELEVTG 401
>ECU06g0340 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 696
Score = 263 bits (672), Expect = 1e-69
Identities = 152/361 (42%), Positives = 216/361 (59%), Gaps = 28/361 (7%)
Query: 482 DQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTT 541
D+ + +++ ++E E + + +IY+++ +SIAP+V+GHE +K+ + + G +
Sbjct: 255 DRSLKTSKMFTEEEEESFKKLSKADIYERISRSIAPSVYGHEDVKRALACMLFGGTRRVL 314
Query: 542 VEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGG 601
+ + LRGDIN+ ++GDP +KSQ LK++ SP VYTSGK SSAAGLTA+V++D GG
Sbjct: 315 EDKVTLRGDINVLLLGDPGMAKSQLLKFMELVSPVGVYTSGKGSSAAGLTASVIRDS-GG 373
Query: 602 DFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSIL 661
+F +E GAL+LADNG+CCIDEFDKMD D+VAIHEAMEQQTISIAKAGI LN RTSIL
Sbjct: 374 EFYLEGGALVLADNGICCIDEFDKMDEHDRVAIHEAMEQQTISIAKAGITTMLNTRTSIL 433
Query: 662 AAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRD 721
AAANPV GRY+ T N+ A I+SRFD F IL D + D LA H++ +H +
Sbjct: 434 AAANPVFGRYDDYKTPDENIEFGATILSRFDCIF-ILKDKHGPNDIILAKHVLSVHQNKA 492
Query: 722 SAINP------PFSAEQLS---------------RYINYAK-----TFKPVMTKEARDYL 755
N EQ+S RY+ YA+ T +K+ Y
Sbjct: 493 REDNECQNGLHDDQEEQISGSDRSPDIIPIHTIKRYVQYARSKVFPTLSEAASKQLSRYY 552
Query: 756 VKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQ 815
V E+R+ + +++ ITVRQLE++IR+ E++A+ + V EA L +
Sbjct: 553 VNTRKEVRQLEQSTLKRNAIPITVRQLEAIIRIGESLAKMELSQIVTEKHVEEAIRLFKV 612
Query: 816 S 816
S
Sbjct: 613 S 613
Score = 52.4 bits (124), Expect = 4e-06
Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 8/178 (4%)
Query: 258 IRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVEQVFKYTEPTSCPN 317
IR+I A+K ++ I G V S + + C C + + ++ + + + T CP
Sbjct: 116 IREINASKTNKIVKIQGIVVSASSVITKPRTLFLVCRNCLSSKEVMDMIPRMCDKTECPP 175
Query: 318 PTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPGDRC 377
+ + +S+ +D Q V+IQE +IP G PR ++L V R PG +
Sbjct: 176 DP------YIVIPEKSQVIDVQYVKIQEFFEDIPVGETPRHFSLVLEKKMVNRLIPGSKV 229
Query: 378 KFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEGLNSGISGLKSLGVRDLTYKIS 435
G + + LP VK D R + + K L D+ +IS
Sbjct: 230 VITGI-YCMRMIRDSSLPIVKVVGLED-RSLKTSKMFTEEEEESFKKLSKADIYERIS 285
>Hs20535929 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 904
Score = 262 bits (669), Expect = 2e-69
Identities = 147/360 (40%), Positives = 221/360 (60%), Gaps = 25/360 (6%)
Query: 479 AETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVH 538
A+ D ++ + L +++ + + KD+ I +K+ SIAP+++GHE IK+G+ L + G
Sbjct: 445 AKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEP 504
Query: 539 KTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDE 598
K K+RGDIN+ + GDP T+KSQFLKY+ S RA++T+G+ +SA GLTA V +
Sbjct: 505 KNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHP 564
Query: 599 EGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNART 658
++T+EAGAL+LAD GVC IDEFDKM+ D+ +IHEAMEQQ+ISI+KAGI +L AR
Sbjct: 565 VSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARC 624
Query: 659 SILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHM 718
+++AAANP+GGRY+ LT N++++ PI+SRFD+ V+ D + D LA +V H+
Sbjct: 625 TVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHV 684
Query: 719 K------------RDSAINP---------PFSAEQLSRYINYAK-TFKPVMTKEARDYLV 756
+ SA P P E L +YI YAK P + + +D +
Sbjct: 685 RHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVA 744
Query: 757 KRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
K Y++LRK + + S ITVR +ES+IR++EA AR + D ++ V A ++ +S
Sbjct: 745 KMYSDLRK---ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLES 801
Score = 81.3 bits (199), Expect = 7e-15
Identities = 40/144 (27%), Positives = 76/144 (52%), Gaps = 3/144 (2%)
Query: 239 DQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRA 298
D++ + + +LP V +R +R + L+ SG VT + + P+L + C C
Sbjct: 275 DRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNF 334
Query: 299 VIDNV-EQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPR 357
V+ + + +P SCP C++ + +N+ + + ++Q++RIQE+ ++ +G +PR
Sbjct: 335 VLGPFCQSQNQEVKPGSCPE--CQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPR 392
Query: 358 TLDIILRGDCVERAKPGDRCKFIG 381
+ D IL D V+ KPGD + G
Sbjct: 393 SKDAILLADLVDSCKPGDEIELTG 416
>CE08392 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 812
Score = 261 bits (668), Expect = 3e-69
Identities = 143/369 (38%), Positives = 216/369 (57%), Gaps = 42/369 (11%)
Query: 487 LTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIK 546
+ + ++ +++++ K N ++ L +S+AP++ GHE KK +L +L G+ K G +
Sbjct: 278 IPNFEPQDVKDVRKISKSRNPFELLARSLAPSICGHEETKKALLCLLLGGMEKILNNGSR 337
Query: 547 LRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIE 606
LRGDIN+ ++GDPS +KSQ L+YV +PRA+ T+G+ SS GLTAAV D + G+ +E
Sbjct: 338 LRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVTTDPDSGERRLE 397
Query: 607 AGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANP 666
AGA++LAD GV CIDEFDKM D+ AIHE MEQ ++I+KAGIHA LNAR S+LAAANP
Sbjct: 398 AGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANP 457
Query: 667 VGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKR-----D 721
V GRYN + N+ M ++SRFDL FV+LD+ + D +A H++ LH R D
Sbjct: 458 VYGRYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTYRTQGEAD 517
Query: 722 SAINPP------------------------------------FSAEQLSRYINYAKTFKP 745
+ P + + + +YI+ A++ +P
Sbjct: 518 GTVLPMGGGVETISTINMETKKASSSIYEENTQWAGIQDTKILTMDFMRKYIHLARSVQP 577
Query: 746 VMTKEARDYLVKRYTELRK-DDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPS 804
+T EA +Y+ + Y ++R D + + + +T RQLE+LIRLS AIA+A ++
Sbjct: 578 KLTDEATEYISEVYADIRSFDITKTDQERTMPVTARQLETLIRLSTAIAKARFSKKVERE 637
Query: 805 FVAEAYDLL 813
+AY+LL
Sbjct: 638 DTEKAYNLL 646
Score = 62.4 bits (150), Expect = 3e-09
Identities = 39/133 (29%), Positives = 64/133 (47%), Gaps = 3/133 (2%)
Query: 259 RDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDNVEQVFKYTEPTSCPN- 317
R ++++ +G+L+ G VT+ S +R +L + C V++ F + N
Sbjct: 119 RTLKSSYLGNLVCCEGIVTKCSTVRQKLLTSVHYCPATNKVLEKKFADFTMLDTAVTNNN 178
Query: 318 -PT-CENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVERAKPGD 375
PT EN++ S + D Q IQE P+G +PR +D + D +R KPGD
Sbjct: 179 YPTEDENKNPLETEFGHSVYKDHQTFTIQELPESAPAGQLPRAVDCVADLDLADRVKPGD 238
Query: 376 RCKFIGTEIVVPD 388
R + IG V+P+
Sbjct: 239 RVRIIGVFRVLPN 251
>ECU08g0290 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 687
Score = 256 bits (653), Expect = 2e-67
Identities = 146/357 (40%), Positives = 215/357 (59%), Gaps = 17/357 (4%)
Query: 462 SKFDYINLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFG 521
S+F + + N N E A E + E+ ++ + ++++K M IAP++FG
Sbjct: 236 SRFRTVVIAN--NIEKAEEEEVEVE-PGVEFERLSQMKNMHH----------LIAPSIFG 282
Query: 522 HETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTS 581
H+ +K+ I L ++ G G K+RGDINI +VGDPST+KSQ L+YV N + ++ T+
Sbjct: 283 HDIVKRSIALLLVGGNEVVMRNGSKIRGDINILLVGDPSTAKSQLLRYVLNAAQLSIATT 342
Query: 582 GKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQ 641
GK SS GLTAAVV D++ G+ +EAGA++LAD GV CIDEFDKM D+VAIHE MEQQ
Sbjct: 343 GKGSSGVGLTAAVVLDKDTGEKRLEAGAMVLADRGVVCIDEFDKMSDGDRVAIHEVMEQQ 402
Query: 642 TISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDC 701
T++IAKAGIH TLNAR S+LAAANP+ G+Y + N+ + +++RFDL FV LD
Sbjct: 403 TVTIAKAGIHTTLNARCSVLAAANPIWGQYKESRPPQDNVRLPESLLTRFDLIFVTLDKS 462
Query: 702 NEKIDTELASHIVDLHMKRDSAINPPFSAEQ--LSRYINYAKTFKPVMTKEARDYLVKRY 759
N ID ++ H++ +HM +Q YI Y + KPV+++EA + + Y
Sbjct: 463 NTDIDQLVSGHVLRMHMLTQGYEEEGMGVKQEVFRAYIRYCRQKKPVLSREAAGLIAREY 522
Query: 760 TELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
T LR+ ++ + IT R LE++IRL+ A A+ D + A +L++ S
Sbjct: 523 TSLRQ--SKDRKEQIVSITPRMLETMIRLATANAKLRLSDVVEYDDAECAVNLVKDS 577
Score = 53.5 bits (127), Expect = 2e-06
Identities = 38/132 (28%), Positives = 61/132 (45%), Gaps = 14/132 (10%)
Query: 259 RDIRANKIGSLMAISGTVTRTSEIRPELYKAS---------FTCELCRAVIDNVEQVFKY 309
R + + IG ++ + G VT S RP++ K+ ++ E A + V
Sbjct: 96 RTLSSVYIGKMVCVEGIVTSCSICRPKVMKSVHYNPSKNVFYSKEYRDATMVTKLPVTNS 155
Query: 310 TEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVE 369
PT + T F S++ D+Q V +QE + P G +PR++++IL D V+
Sbjct: 156 VYPTRDVDGTLLTTEF-----GLSEYFDYQTVVLQEMPEKAPPGQLPRSVEVILSFDLVD 210
Query: 370 RAKPGDRCKFIG 381
KPGDR K G
Sbjct: 211 GLKPGDRAKIYG 222
>At1g44900 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 928
Score = 251 bits (641), Expect = 4e-66
Identities = 149/356 (41%), Positives = 210/356 (58%), Gaps = 25/356 (7%)
Query: 483 QEIFLT-RLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTT 541
Q++F +L ++ +++E+ KD I ++++KSIAP+++GHE IK + L M G K
Sbjct: 466 QDLFSAYKLTQEDKTQIEELSKDPRIVERIIKSIAPSIYGHEDIKTALALAMFGGQEKNI 525
Query: 542 VEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGG 601
+LRGDIN+ ++GDP T+KSQFLKYV RAVYT+GK +SA GLTAAV KD
Sbjct: 526 KGKHRLRGDINVLLLGDPGTAKSQFLKYVEKTGQRAVYTTGKGASAVGLTAAVHKDPVTR 585
Query: 602 DFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSIL 661
++T+E GAL+LAD G+C IDEFDKM+ D+V+IHEAMEQQ+ISI+KAGI +L AR S++
Sbjct: 586 EWTLEGGALVLADRGICLIDEFDKMNDQDRVSIHEAMEQQSISISKAGIVTSLQARCSVI 645
Query: 662 AAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKR- 720
AAANPVGGRY+ + N+ ++ PI+SRFD+ V+ D + D LA +V+ H K
Sbjct: 646 AAANPVGGRYDSSKSFAQNVELTDPILSRFDILCVVKDVVDPVTDEMLAEFVVNSHFKSQ 705
Query: 721 -----------------DSAINPPFSAEQ--LSRYINYAKTFK-PVMTKEARDYLVKRYT 760
S P Q L +Y+ Y+K + P + + L Y
Sbjct: 706 PKGGKMEDSDPEDGIQGSSGSTDPEVLPQNLLKKYLTYSKLYVFPKLGELDAKKLETVYA 765
Query: 761 ELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
LR++ G S I R LES+IR+SEA AR + + V A +L S
Sbjct: 766 NLRRESMNGQGVS---IATRHLESMIRMSEAHARMHLRQYVTEEDVNMAIRVLLDS 818
Score = 81.3 bits (199), Expect = 7e-15
Identities = 42/145 (28%), Positives = 80/145 (54%), Gaps = 1/145 (0%)
Query: 237 NPDQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELC 296
N + + + NLP +IR+IR + +++ I G VTR S + P+L + + C C
Sbjct: 291 NYKNIHTKIYVRVTNLPVNDQIRNIRQIHLNTMIRIGGVVTRRSGVFPQLQQVKYDCNKC 350
Query: 297 RAVIDNVEQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMP 356
AV+ Q Y+E C+++ +++NV ++ + ++QK+ IQE+ +P+G +P
Sbjct: 351 GAVLGPFFQN-SYSEVKVGSCSECQSKGPFTVNVEQTIYRNYQKLTIQESPGTVPAGRLP 409
Query: 357 RTLDIILRGDCVERAKPGDRCKFIG 381
R ++IL D ++ A+PG+ + G
Sbjct: 410 RHKEVILLNDLIDCARPGEEIEVTG 434
>YBL023c [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 868
Score = 248 bits (632), Expect = 4e-65
Identities = 146/373 (39%), Positives = 217/373 (58%), Gaps = 49/373 (13%)
Query: 478 AAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGV 537
A E ++ + + +E E +++ +D I DK++ S+AP+++GH IK + + GV
Sbjct: 464 ANEGEEGLDVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGV 523
Query: 538 HKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKD 597
K +RGDIN+ ++GDP T+KSQ LKYV + RAV+ +G+ +SA GLTA+V KD
Sbjct: 524 PKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKD 583
Query: 598 EEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNAR 657
++T+E GAL+LAD GVC IDEFDKM+ D+ +IHEAMEQQ+ISI+KAGI TL AR
Sbjct: 584 PITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQAR 643
Query: 658 TSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH 717
SI+AAANP GGRYN L L N++++ PI+SRFD+ V+ D +E+ D LA+ +VD H
Sbjct: 644 CSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSH 703
Query: 718 MKR-----------------DSAIN---------------------------PPFSAEQL 733
++ +SAI P E L
Sbjct: 704 VRSHPENDEDREGEELKNNGESAIEQGEDEINEQLNARQRRLQRQRKKEEEISPIPQELL 763
Query: 734 SRYINYAKT-FKPVMTKEARDYLVKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAI 792
+YI+YA+T P + + D + + Y +LR+ + S S+ ITVR LES++R++E+
Sbjct: 764 MKYIHYARTKIYPKLHQMDMDKVSRVYADLRR---ESISTGSFPITVRHLESILRIAESF 820
Query: 793 ARANCVDEIVPSF 805
A+ + E V S+
Sbjct: 821 AKMR-LSEFVSSY 832
Score = 75.1 bits (183), Expect = 5e-13
Identities = 37/147 (25%), Positives = 82/147 (55%), Gaps = 11/147 (7%)
Query: 240 QVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAV 299
++ + + + PT++ +R++R + + SL+ ++G VTR + + P+L F C C ++
Sbjct: 288 RIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSI 347
Query: 300 I-----DNVEQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGS 354
+ D+ E++ + C N C+++ + +N ++ + ++Q+V +QE +P G
Sbjct: 348 LGPFFQDSNEEI----RISFCTN--CKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGR 401
Query: 355 MPRTLDIILRGDCVERAKPGDRCKFIG 381
+PR ++IL D V+ +KPG+ + G
Sbjct: 402 LPRHREVILLADLVDVSKPGEEVEVTG 428
>ECU04g0850 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 780
Score = 245 bits (625), Expect = 3e-64
Identities = 139/334 (41%), Positives = 208/334 (61%), Gaps = 12/334 (3%)
Query: 490 LDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRG 549
+ D++ E+K+M + I ++ SIAP+V+GH +K+ I L ML GV + + ++RG
Sbjct: 358 MTDDDVREIKKMGRHPEIKRIVINSIAPSVYGHAEVKRAIALAMLGGVARESTSH-RIRG 416
Query: 550 DINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGA 609
DIN+ ++GDP +KSQFL+YV + S RAV +G+ +S+ GLTA+V KD ++T+E GA
Sbjct: 417 DINVLLLGDPGMAKSQFLRYVESTSHRAVLATGQGASSVGLTASVRKDPVVKEWTLEGGA 476
Query: 610 LMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGG 669
L+LAD G+C IDEFDKM+ D+ +IHEAMEQQ+ISI+KAGI ATL+AR S++AAANP+ G
Sbjct: 477 LVLADKGICLIDEFDKMNEHDRTSIHEAMEQQSISISKAGIVATLHARCSVIAAANPMRG 536
Query: 670 RYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH---MKRDSAINP 726
RYN LT N+N+S PI+SRFD+ V+ D + D + A +++ H ++ +P
Sbjct: 537 RYNGSLTFAQNVNLSDPIISRFDILCVVKDAIDAGEDEKTAKFVIESHEGGEEKPDGFDP 596
Query: 727 P---FSAEQLSRYINYAKT-FKPVMTKEARDYLVKRYTELRKDDAQGYSKSSYRITVRQL 782
E L +YI YA+T P + + Y ELRK+ S +TVR +
Sbjct: 597 KRMMMGHELLRKYILYARTNVVPAFNDVDMEKISSLYLELRKESL----PSGLPVTVRHV 652
Query: 783 ESLIRLSEAIARANCVDEIVPSFVAEAYDLLRQS 816
ES++R+SEA A+ + + EA ++ S
Sbjct: 653 ESIVRISEAFAKMRLSRVVSVEDIDEAISVVLDS 686
Score = 79.3 bits (194), Expect = 3e-14
Identities = 44/133 (33%), Positives = 75/133 (56%), Gaps = 6/133 (4%)
Query: 250 LNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRAVIDN-VEQVFK 308
++LP +R +R +G L+ +SG VTR S + P F+C CR+V V FK
Sbjct: 194 VDLPVCDSVRSLRNRHLGKLVRVSGVVTRRSGVFPLYSIVKFSCLKCRSVFGPFVASSFK 253
Query: 309 YTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCV 368
PT C C+++ +++N + + + D+QK+ IQE +P GS+PR+ +++L D +
Sbjct: 254 ---PTHCFE--CQSKGPFTVNTSETVYKDFQKLTIQEIPGSVPPGSLPRSKEVLLFYDLI 308
Query: 369 ERAKPGDRCKFIG 381
+ AKPG+ + G
Sbjct: 309 DCAKPGEEVEVTG 321
>Hs4758706 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 892
Score = 242 bits (618), Expect = 2e-63
Identities = 135/329 (41%), Positives = 201/329 (61%), Gaps = 25/329 (7%)
Query: 479 AETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQMLSGVH 538
A+ D ++ + L +++ + + KD+ I +K+ SIAP+++GHE IK+G L + G
Sbjct: 434 AKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGPALALFGGEP 493
Query: 539 KTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAVVKDE 598
K K+RGDIN+ + GDP T+KSQFLKY+ S RA++T+G+ +SA +TA V +
Sbjct: 494 KNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVAVTAYVQRHP 553
Query: 599 EGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATLNART 658
++T+EAGAL+LAD GVC IDEFDKM+ D+ +IHEAMEQQ+ISI+KAGI +L AR
Sbjct: 554 VSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARC 613
Query: 659 SILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHM 718
+++AAANP+GGRY+ LT N++++ PI+SRFD+ V+ D + D LA +V H+
Sbjct: 614 TVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHV 673
Query: 719 K------------RDSAINP---------PFSAEQLSRYINYAK-TFKPVMTKEARDYLV 756
+ SA P P E L +YI YAK P + + +D +
Sbjct: 674 RHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVA 733
Query: 757 KRYTELRKDDAQGYSKSSYRITVRQLESL 785
K Y++LRK + + S ITVR +ES+
Sbjct: 734 KMYSDLRK---ESMATGSIPITVRHIESM 759
Score = 73.2 bits (178), Expect = 2e-12
Identities = 37/144 (25%), Positives = 73/144 (50%), Gaps = 3/144 (2%)
Query: 239 DQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRA 298
D++ + + +LP V +R +R + L+ SG VT + + P+L + C C
Sbjct: 264 DRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNF 323
Query: 299 VIDNV-EQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENSNEIPSGSMPR 357
V+ + + +P SCP C++ + +N+ + + ++Q++RIQE+ ++ + +PR
Sbjct: 324 VLGPFCQSQNQEVKPGSCPE--CQSAGPFEVNMEETIYQNYQRIRIQESPGKVAARRLPR 381
Query: 358 TLDIILRGDCVERAKPGDRCKFIG 381
+ D IL D V+ GD + G
Sbjct: 382 SKDAILLADLVDSCNAGDEIELTG 405
>ECU09g1360 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 694
Score = 234 bits (596), Expect = 7e-61
Identities = 127/305 (41%), Positives = 186/305 (60%), Gaps = 11/305 (3%)
Query: 509 DKLVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLK 568
+++V+SIAP +FG E IKK +LL ++ + +G+K+RGDIN+ +VGDP +KSQ LK
Sbjct: 321 EQMVRSIAPEIFGMEDIKKILLLMLIGAPGRVREDGMKIRGDINVLLVGDPGIAKSQLLK 380
Query: 569 YVCNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDI 628
R VYT+GK SS GLTA+V KD G+ +E GAL+LAD G+CCIDE DKM+
Sbjct: 381 TCVKIGRRGVYTTGKGSSGVGLTASVSKDPITGEMVLEGGALVLADGGICCIDELDKMNE 440
Query: 629 ADQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIM 688
D+V+IHE MEQQ++SI+KAGI+ +LNAR +L AANPV G+Y+ + ++ N+ + ++
Sbjct: 441 VDRVSIHEVMEQQSVSISKAGINTSLNARCCVLGAANPVKGKYDTRQSIEHNIGLPCALL 500
Query: 689 SRFDLFFVILDDCNEKIDTELASHIVDLHMKRDSAINPPFSAEQLSRYINYAKTFKPVMT 748
SRFD+ ++ D+ N + D LA+HI +H+ + P +++ I+ AK PV+
Sbjct: 501 SRFDVVAILRDEPNLEKDESLANHITSIHLHEEPESIP---YDKIRLIIDEAKRINPVLP 557
Query: 749 KEARDYLVKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIARANCVDEIVPSFVAE 808
L Y + RK+ S +T R L SLIRLS A R ++ V E
Sbjct: 558 SHLSGKLTDAYVKARKE--------SPYVTPRYLLSLIRLSLAHCRLRLSTDVNEDDVNE 609
Query: 809 AYDLL 813
A L+
Sbjct: 610 ALRLM 614
Score = 66.6 bits (161), Expect = 2e-10
Identities = 42/126 (33%), Positives = 67/126 (52%), Gaps = 7/126 (5%)
Query: 255 VHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTCELCRA-VIDNVE-QVFKYTEP 312
V+ +R +++ IGSL+ +SG VT+ S+++P + A++ CE C A V+ VF E
Sbjct: 144 VYSVRGLKSMHIGSLVRVSGVVTKVSQVKPSIRVATYVCEGCGAETYQEVDGDVFDLLE- 202
Query: 313 TSCPNPTCENQSFWS---LNVNRSKFLDWQKVRIQENSNEIPSGSMPRTLDIILRGDCVE 369
C + C ++ L SKF+ Q V +QE + +IP G +PRTL E
Sbjct: 203 -ECGSEKCRIRNVRGTLVLVTRGSKFIKHQTVYMQELTGDIPRGCIPRTLVAECYSSMAE 261
Query: 370 RAKPGD 375
+ +PGD
Sbjct: 262 KCRPGD 267
>ECU11g0800 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 681
Score = 186 bits (471), Expect = 2e-46
Identities = 136/463 (29%), Positives = 223/463 (47%), Gaps = 64/463 (13%)
Query: 356 PRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRGISRTTEG- 414
PRT RG C R+ R E+ DV ++ + + S D GI + +
Sbjct: 162 PRTC----RGSCNSRSFAPVRNH---PEVEYRDVQEIKIQELYGGSEGDGNGIPKAVDCI 214
Query: 415 LNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYINLRNYQN 474
L +G + G D+ + L +EN IN K F ++ YQ+
Sbjct: 215 LYDEFAGTLAPG--DIVEIVGVLGVELENDNLYKLTVHINNLQIVKNKNF-FVEDVEYQS 271
Query: 475 YEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKKGILLQML 534
+ A E +++ N LV S+ AV+G+E IK G++L +
Sbjct: 272 RDFA------------------EFRKIAGAGNTLASLVCSLYSAVYGNELIKVGLVLSLF 313
Query: 535 SGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNFSPRAVYTSGKASSAAGLTAAV 594
G K+ + +R + ++ IVGDP KS+ L C P++ Y SG ++ AGLT ++
Sbjct: 314 GGTKKSAGQH-SIRSETHVLIVGDPGLGKSRLLLSTCGILPKSSYVSGSFTTTAGLTVSL 372
Query: 595 VKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIADQVAIHEAMEQQTISIAKAGIHATL 654
D G++ +AGAL++ADNG+CC+DEFDK+D D A+ EAME Q +SIAK G+ ++
Sbjct: 373 THDPVSGEYMADAGALVVADNGICCLDEFDKID--DHAALFEAMEDQKVSIAKGGVICSV 430
Query: 655 NARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSRFDLFFVILDDCNEKIDTELASHIV 714
R +++AA NP G ++R T+ N+ ++SRFDL F++LDD +EK ++ I+
Sbjct: 431 PTRATVIAATNPRHGHFDRGKTMAENIRFDPGLLSRFDLIFLLLDDLSEKESYMISGQIL 490
Query: 715 DLH----------------MKRDSAINP------PFSAEQLSRYINYAK-TFKPVMTKEA 751
++RD + + + + +YI+YA+ PV++K A
Sbjct: 491 KKRRTLSPGEGGFDDVVETVRRDMFVEDIRSGGCVYPMDIVRKYISYARANVFPVLSKSA 550
Query: 752 RDYLVKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEAIAR 794
+ + + Y +R S ++ R LESL+RL+EA A+
Sbjct: 551 SEAIKEYYVGMR---------SRGGVSTRDLESLVRLTEARAK 584
>ECU07g0490 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 563
Score = 162 bits (409), Expect = 3e-39
Identities = 107/287 (37%), Positives = 165/287 (57%), Gaps = 17/287 (5%)
Query: 511 LVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYV 570
LV S A + G E +K G+LL ++SG H + R + +I +VGD T KS LK
Sbjct: 224 LVNSFAEEIQGLENVKLGLLLALVSGSHGADQKS-GTRSNSHILLVGDSGTGKSHLLKTC 282
Query: 571 CNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIAD 630
AV T+G ++ AGLT V+ +G ++ +EAGAL+LAD G+CCIDEF+K+ + +
Sbjct: 283 SRLLSPAVLTNGVGTTQAGLTTCAVR--QGREWVLEAGALVLADTGLCCIDEFNKLKVNE 340
Query: 631 QVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSR 690
+ + EAMEQQT+SIAKAGI ++LN R S++AA N +Y+ ++ N+ ++ P++SR
Sbjct: 341 KNGLLEAMEQQTLSIAKAGIVSSLNTRCSVIAAIN-TRHKYSFNKSISENIMVATPLISR 399
Query: 691 FDLFFVILDDCNEKIDTELASHIV------DLHMKRDSAINPPFSAEQLSRYINYAKTFK 744
FDL F + DD + + D + I+ L K+ ++ + L YI A+ +
Sbjct: 400 FDLIFGLFDDRDGRSDLLIVDKILGRRPETGLTDKKQGSV--CWDHNILRNYIGVARKRR 457
Query: 745 PVMTKEARDYLVKRYTELRKDDAQGYSKSSYRITVRQLESLIRLSEA 791
V+ + L+ Y RK A+G ++ + TVR LESL RL+EA
Sbjct: 458 AVIPDDLNAVLLSYYHHRRK--AEGANEFN---TVRMLESLARLTEA 499
>At2g14050 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 610
Score = 144 bits (364), Expect = 5e-34
Identities = 75/156 (48%), Positives = 101/156 (64%), Gaps = 4/156 (2%)
Query: 511 LVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYV 570
+++ I P VFG T+K + L ++ GV G K+RG+ ++ ++GDP T KSQFLK+
Sbjct: 319 ILRGICPQVFGLFTVKLAVALTLIGGVQHVDASGTKVRGESHLLLIGDPGTGKSQFLKFA 378
Query: 571 CNFSPRAVYTSGKASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGVCCIDEFDKMDIAD 630
S RAV T+G S++AGLT VKD GG++ +EAGAL+LAD G+CCIDEFD M D
Sbjct: 379 AKLSNRAVITTGLGSTSAGLTVTAVKD--GGEWMLEAGALVLADGGLCCIDEFDSMREHD 436
Query: 631 QVAIHEAMEQQTISIAKAGIHATLNARTSILAAANP 666
+ IHEAMEQQ+IS+AK I LN L + P
Sbjct: 437 RATIHEAMEQQSISVAK--IQKILNGMQLYLLTSLP 470
Score = 59.7 bits (143), Expect = 2e-08
Identities = 38/148 (25%), Positives = 72/148 (47%), Gaps = 7/148 (4%)
Query: 234 IATNPDQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELYKASFTC 293
I T+ +ER + T I +R G LM + GTV R+ ++ + + C
Sbjct: 103 INTSGSPLERSPADFDFDTETFPSIGRVRVKHRGILMMLKGTVIRSGAVKMYEGEKMYRC 162
Query: 294 ELCR---AVIDNVEQVFKYTEPTSCPNP---TCENQSFWSLNVNRSKFLDWQKVRIQENS 347
C+ + +E + +P CP+ CE +F ++ ++ D+Q+++IQEN+
Sbjct: 163 RKCKHMFPIFPELESINSIVKPPFCPSQRSKACEGTNFDPVDDTVTRH-DYQEIKIQENT 221
Query: 348 NEIPSGSMPRTLDIILRGDCVERAKPGD 375
+ G +PR++ ++L+ D V+ K GD
Sbjct: 222 QVLGVGVIPRSILVVLKDDLVDNVKAGD 249
>SPCC16A11.17 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 546
Score = 112 bits (280), Expect = 3e-24
Identities = 82/333 (24%), Positives = 152/333 (45%), Gaps = 50/333 (15%)
Query: 228 GTAPSTIATNPDQVERVLQISFLNLPTVHRIRDIRANKIGSLMAISGTVTRTSEIRPELY 287
GT P N ++ ++ +I NL +RD+ I L++I G V R + + P++
Sbjct: 262 GTNPPEDVLNDIEL-KIYKIRPFNLEKCINMRDLNPGDIDKLISIKGLVLRCTPVIPDMK 320
Query: 288 KASFTCELCRAVIDNVEQVFKYTEPTSCPNPTCENQSFWSLNVNRSKFLDWQKVRIQENS 347
+A F C +C + + EP CP C + L NRS+F D Q +++QE
Sbjct: 321 QAFFRCSVCGHCVTVEIDRGRIAEPIKCPREVCGATNAMQLIHNRSEFADKQVIKLQETP 380
Query: 348 NEIPSGSMPRTLDIILRGDCVERAKPGDRCKFIGTEIVVPDVSQLGLPGVKASSTPDSRG 407
+ +P G P ++ + + + V+ A+ GDR + G VP
Sbjct: 381 DVVPDGQTPHSVSLCVYDELVDSARAGDRIEVTGIFRCVP-------------------- 420
Query: 408 ISRTTEGLNSGISGLKSLGVRDLTYKISFLACHVENVGTSFNGSRINEEDADKTSKFDYI 467
LN + +KSL +K H++ G+ + ++D
Sbjct: 421 -----VRLNPRMRTVKSL------FKTYVDVVHIKKQDKRRLGTDPSTLESDIAE----- 464
Query: 468 NLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDENIYDKLVKSIAPAVFGHETIKK 527
+ A + D+ + ++ +E+ +++++ K ++IYD L +S+AP+++ + +KK
Sbjct: 465 --------DAALQIDE---VRKISDEEVEKIQQVSKRDDIYDILSRSLAPSIYEMDDVKK 513
Query: 528 GILLQMLSGVHKTTVEGI--KLRGDINICIVGD 558
G+LLQ+ G +K+ +G + RGDINI + GD
Sbjct: 514 GLLLQLFGGTNKSFHKGASPRYRGDINILMCGD 546
>7300061 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 755
Score = 109 bits (273), Expect = 2e-23
Identities = 82/267 (30%), Positives = 132/267 (48%), Gaps = 18/267 (6%)
Query: 455 EEDADKTSKFDYINLRNYQNYEMAAETDQEIFLTRLDSDEINELKEMVKDE-NIYDKLVK 513
+E D T+ D N Q Y A + R S+ E M+ E N + LV+
Sbjct: 379 QELGDDTTTGDTSN--QMQPYLKAVSIRDASSIKREFSERDLEAIVMINAEPNSFKLLVQ 436
Query: 514 SIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYVCNF 573
SIAP V+GHE K LL +L G T IN+ +VGDP K++ L+
Sbjct: 437 SIAPEVYGHELPKAACLLSLLGGKGAETEA-------INVLLVGDPGIGKTKILQSCAQI 489
Query: 574 SPRAVYTSGK--ASSAAGLTAAVVKDEEGGDFTIEAGALMLADNGV-CCIDEFDKMDIAD 630
+ R + SGK A SA L + ++AG+LM+A G C +D+ DK+ +
Sbjct: 490 AERGAHVSGKRGAQSAQQLGVTFAGRNKR---VLQAGSLMMASGGGHCTLDDVDKL-ASK 545
Query: 631 QVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLTLRSNLNMSAPIMSR 690
Q + + ++ + +++ AG A+ A+ S++A ANP G+Y+ L N+N+S ++
Sbjct: 546 QAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQNINISPSLLRE 605
Query: 691 FDLFFVILDDCNEKIDTELASHIVDLH 717
F L +++LD +E+ D L +H+ LH
Sbjct: 606 FHLVYILLDKPSER-DMSLTAHVRALH 631
>Hs22056246 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 112
Score = 73.6 bits (179), Expect = 1e-12
Identities = 31/80 (38%), Positives = 52/80 (64%)
Query: 511 LVKSIAPAVFGHETIKKGILLQMLSGVHKTTVEGIKLRGDINICIVGDPSTSKSQFLKYV 570
++ S+ P VFG +K + + + G+ +T G ++RG+ ++ +VGDP T KSQFLKY
Sbjct: 27 ILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYA 86
Query: 571 CNFSPRAVYTSGKASSAAGL 590
+PR+V T+G S++AG+
Sbjct: 87 AKITPRSVLTTGIGSTSAGI 106
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,309,845
Number of Sequences: 60738
Number of extensions: 2392239
Number of successful extensions: 5612
Number of sequences better than 1.0e-05: 51
Number of HSP's better than 0.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 5368
Number of HSP's gapped (non-prelim): 118
length of query: 1003
length of database: 30,389,216
effective HSP length: 116
effective length of query: 887
effective length of database: 23,343,608
effective search space: 20705780296
effective search space used: 20705780296
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)