ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2787 good AR KOG2190 General function prediction only PolyC-binding proteins alphaCP-1 and related KH domain proteins
r_klactVI2787 good AR KOG2190 RNA processing and modification PolyC-binding proteins alphaCP-1 and related KH domain proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2787 985551 984301 -417
(417 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR233w [AR] KOG2190 PolyC-binding proteins alphaCP-1 and relate... 332 6e-91
SPCC757.09c [AR] KOG2190 PolyC-binding proteins alphaCP-1 and re... 124 2e-28
Hs10092617 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 121 2e-27
Hs5453854 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rela... 115 9e-26
7296507 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and relate... 108 2e-23
Hs14141168 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 106 7e-23
Hs14670369 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 105 1e-22
Hs14141166 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 105 1e-22
At3g04610 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rela... 86 8e-17
Hs14670371 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 83 9e-16
CE27461 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and relate... 78 3e-14
YBL032w [AR] KOG2190 PolyC-binding proteins alphaCP-1 and relate... 73 9e-13
At1g14170 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rela... 70 8e-12
At5g15270 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rela... 65 2e-10
CE09674 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnRNP ... 62 2e-09
At4g26000 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rela... 62 2e-09
Hs20539507 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains... 61 4e-09
Hs14740532 [A] KOG1676 K-homology type RNA binding proteins 60 5e-09
Hs5729901 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains ... 60 8e-09
At5g04430 [AR] KOG2191 RNA-binding protein NOVA1/PASILLA and rel... 59 1e-08
HsM5729882 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains... 58 3e-08
Hs21361352 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains... 57 4e-08
Hs4504865 [A] KOG1676 K-homology type RNA binding proteins 55 1e-07
Hs14165437 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnR... 55 1e-07
Hs14165435 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnR... 55 1e-07
Hs5729884 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains ... 55 2e-07
At5g64390 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rela... 54 6e-07
Hs17402900 [A] KOG1676 K-homology type RNA binding proteins 53 7e-07
Hs6031187 [AR] KOG2191 RNA-binding protein NOVA1/PASILLA and rel... 53 1e-06
Hs4505425 [AR] KOG2191 RNA-binding protein NOVA1/PASILLA and rel... 53 1e-06
Hs18560043 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnR... 51 4e-06
Hs5902724 [AR] KOG2191 RNA-binding protein NOVA1/PASILLA and rel... 50 6e-06
>YBR233w [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 413
Score = 332 bits (851), Expect = 6e-91
Identities = 196/418 (46%), Positives = 268/418 (63%), Gaps = 51/418 (12%)
Query: 14 SPNSLKRKPDHET----LEAGIKRVALEDNEAEPQNSELNGDGTHLTEKDSGQVPNYINL 69
SPN+LKRK +T LEA IKRVAL+D ++ N + D VP+ ++L
Sbjct: 20 SPNTLKRKKGEDTSEEQLEAEIKRVALKDADSHSDNDHDSPDN----------VPSDVHL 69
Query: 70 RMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRGKCEEVARAFGK 129
RMLCL+K AS +VG KG ++RIKSET+ RIN+S+NI GV ER+++VRG C++VA+A+G
Sbjct: 70 RMLCLVKHASLIVGHKGATISRIKSETSARINISNNIRGVPERIVYVRGTCDDVAKAYGM 129
Query: 130 IVRAINNESDDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIEDLSAARLMASPQQL 189
IVRA+ E ++ N + + +NLLIPHH MGCIIG++GSRL EIEDLSAA+L ASP QL
Sbjct: 130 IVRALLEEHGNEDNGEDIEISINLLIPHHLMGCIIGKRGSRLREIEDLSAAKLFASPNQL 189
Query: 190 PMSNDRILSLTGVADAIHIATYYIGQTIL--ENESKLKN-KKSVFYHPGPMHSVLVNNYQ 246
+SNDRIL++ GV DAIHIAT+YI QT+L + ES KN K+S++Y P +SVL+++ Q
Sbjct: 190 LLSNDRILTINGVPDAIHIATFYISQTLLNFQMESPQKNVKRSIYYQPTQFNSVLIDHSQ 249
Query: 247 MYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRRTKP-PVSKYPIG---PQQSL 302
I+ HQ +HQYHP DK + K P+S + PQ +
Sbjct: 250 PNTIF-----------------HQRNHQYHPSDKLLSYKPNKNLPISSTLLSMATPQYTT 292
Query: 303 QPYTDMVDSCKHVKI--ISQLQQSPISP----HLVL---PQEVFIDNKFVGNVIGKGGKN 353
+ + I ++ L ISP HL++ QE+FID KFVGNVIGK GK+
Sbjct: 293 ASVANATAFQPNFVIPNVTVLDGPVISPAPGNHLLMNFVQQEIFIDEKFVGNVIGKDGKH 352
Query: 354 IQQIKQSTGCMIKINDPVEGLDERKLVLIGTPLATQTAIMMINNRIDMDK----RKRQ 407
I +K+STGC I I DPVEG ER+L + GT +A+Q AIM+I+N+I++D+ RKR+
Sbjct: 353 INSVKESTGCSIIIQDPVEGSSERRLTIRGTFMASQAAIMLISNKIEIDRSNAERKRR 410
>SPCC757.09c [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 398
Score = 124 bits (312), Expect = 2e-28
Identities = 88/352 (25%), Positives = 164/352 (46%), Gaps = 45/352 (12%)
Query: 59 DSGQVPNYINLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRG 118
D+ + LR L ++A ++G G+ V ++S TN + V+ + V +RV+ + G
Sbjct: 86 DATYATQQLTLRALLSTREAGIIIGKAGKNVAELRSTTNVKAGVTKAVPNVHDRVLTISG 145
Query: 119 KCEEVARAFGKIVRAINNES---DDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIE 175
E V RA+ I+ S D ++ + P + LLI H MG IIGR G R+ I+
Sbjct: 146 PLENVVRAYRFIIDIFAKNSTNPDGTPSDANTPRKLRLLIAHSLMGSIIGRNGLRIKLIQ 205
Query: 176 DLSAARLMASPQQLPMSNDRILSLTGVADAIHIATYYIGQTILENESKLKNKKSVFYHPG 235
D + R++AS LP S +R + + G D +H A + IG+ ++++ + +VFY+P
Sbjct: 206 DKCSCRMIASKDMLPQSTERTVEIHGTVDNLHAAIWEIGKCLIDDWE--RGAGTVFYNP- 262
Query: 236 PMHSVLVNNYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRRTKPPVSKYP 295
+ + S + +PQ ++P AP + P + + + P
Sbjct: 263 -------VSRLTQPLPSLASTASPQQVSPPAAPSTTSGEAIPENFVSYGAQVFPATQ--- 312
Query: 296 IGPQQSLQPYTDMVDSCKHVKIISQLQQSPISPHLVLPQEVFIDNKFVGNVIGKGGKNIQ 355
P+ LQQ ++ ++ +P ++ VG +IG+GG I
Sbjct: 313 -------MPF---------------LQQPKVTQNISIPADM------VGCIIGRGGSKIS 344
Query: 356 QIKQSTGCMIKI-NDPVEGLDERKLVLIGTPLATQTAIMMINNRIDMDKRKR 406
+I++++G I I +P + ER + GT + A+ ++ +++M+K +R
Sbjct: 345 EIRRTSGSKISIAKEPHDETGERMFTITGTHEENEKALFLLYQQLEMEKDRR 396
>Hs10092617 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 339
Score = 121 bits (303), Expect = 2e-27
Identities = 96/341 (28%), Positives = 164/341 (47%), Gaps = 33/341 (9%)
Query: 67 INLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRGKCEEVARA 126
+ +R+L K+ ++G KGE V +++ E+ RIN+S+ ER++ + G + + +A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG--NCPERIVTITGPTDAIFKA 71
Query: 127 FGKIVRA-----INNESDDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIEDLSAAR 181
F I IN+ S+ + + P+ + L++P G +IG+ GS++ EI + + A+
Sbjct: 72 FAMIAYKFEEDIINSMSNSPATSKP-PVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQ 130
Query: 182 LMASPQQLPMSNDRILSLTGVADAIHIATYYIGQTILENESKLKNKKSVFYHPGPMHS-V 240
+ + LP S +R ++++G DAI I +LE+ K ++ Y P P + V
Sbjct: 131 VQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPK---GATIPYRPKPASTPV 187
Query: 241 LVNNYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRRTKPPVSKY-PIGPQ 299
+ Q Y I A +P +T + HQ Q P PP+ + P P
Sbjct: 188 IFAGGQAYTIQGQYAIPHPDQLTKL---HQLAMQQTPF----------PPLGQTNPAFPG 234
Query: 300 QSLQPYTDMVDSCKHVKIISQLQQSP-ISPHLVLPQEVFIDNKFVGNVIGKGGKNIQQIK 358
+ L P ++ + S L SP S H E+ I N +G +IG+ G I +I+
Sbjct: 235 EKL-PLHSSEEAQNLMGQSSGLDASPPASTH-----ELTIPNDLIGCIIGRQGTKINEIR 288
Query: 359 QSTGCMIKINDPVEGLDERKLVLIGTPLATQTAIMMINNRI 399
Q +G IKI + EG ER++ + GTP A +IN R+
Sbjct: 289 QMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARL 329
>Hs5453854 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 356
Score = 115 bits (289), Expect = 9e-26
Identities = 92/348 (26%), Positives = 163/348 (46%), Gaps = 21/348 (6%)
Query: 67 INLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRGKCEEVARA 126
+ +R+L K+ ++G KGE V RI+ E+ RIN+S+ ER+I + G + +A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEG--NCPERIITLTGPTNAIFKA 71
Query: 127 FGKIV----RAINNESDDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIEDLSAARL 182
F I+ IN+ + + P+ + L++P G +IG+ G ++ EI + + A++
Sbjct: 72 FAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQV 131
Query: 183 MASPQQLPMSNDRILSLTGVADAIHIATYYIGQTILENESKLKNKK--SVFYHPGPMHS- 239
+ LP S +R +++ GV ++ I +LE S+ + ++ Y P P S
Sbjct: 132 QVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSP 191
Query: 240 VLVNNYQMYMIYSGGAPTNPQDIT--PMVAPH-QEHHQYHPMDKKTMNRRTKPPVSKYPI 296
V+ Q + G P D+ P+ A Q H P+D +N+ + +
Sbjct: 192 VICAGGQDRCSDAVGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVAR---QQSHF 248
Query: 297 GPQQSLQPYTDMVDSCKHVK-IISQLQQSPISPHLVLPQEVFIDNKFVGNVIGKGGKNIQ 355
+ + S VK + L S + H E+ I N +G +IG+ G NI
Sbjct: 249 AMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTH-----ELTIPNNLIGCIIGRQGANIN 303
Query: 356 QIKQSTGCMIKINDPVEGLDERKLVLIGTPLATQTAIMMINNRIDMDK 403
+I+Q +G IKI +PVEG R++ + G+ + A +IN R+ +K
Sbjct: 304 EIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEK 351
>7296507 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 386
Score = 108 bits (269), Expect = 2e-23
Identities = 93/372 (25%), Positives = 167/372 (44%), Gaps = 21/372 (5%)
Query: 42 EPQNSELNGDGTHLTEKDSGQVPNYINLRMLCLMKQASKVVGGKGERVNRIKSETNTRIN 101
E N+ + G + +D + +R++ K+ ++G KGE VNR + E+ +IN
Sbjct: 2 EDNNTSSSAGGASIKHEDPSVT---LTIRLIMQGKEVGSIIGKKGEIVNRFREESGAKIN 58
Query: 102 VSDNINGVMERVIFVRGKCEEVARAFGKIVRAIN---NESDDDSNERSLPLVVNLLIPHH 158
+SD ER++ V G + AF I + ++ +D + + L++P
Sbjct: 59 ISDG--SCPERIVTVSGTTNAIFSAFTLITKKFEEWCSQFNDVGKVGKTQIPIRLIVPAS 116
Query: 159 FMGCIIGRQGSRLHEIEDLSAARLMASPQQLPMSNDRILSLTGVADAIHIATYYIGQTIL 218
G +IG+ GS++ EI + + + + LP S +R ++L+G A+ I Y I +L
Sbjct: 117 QCGSLIGKSGSKIKEIRQTTGCSIQVASEMLPNSTERAVTLSGSAEQITQCIYQICLVML 176
Query: 219 ENESKLKNKKSVFYHPGPMHS--VLVNNYQMYMIYSGGA-PTNPQDITPMVA-PHQEHHQ 274
E+ + ++ Y P P + V++ N Q + I A PT P+ +
Sbjct: 177 ESPPR---GATIPYRPKPQVTGPVILANGQAFTIQGNYAVPTQEVAKNPLASLAALGLAG 233
Query: 275 YHPMDKKTMNRRTKPPVSKYPIGPQQSLQPYTDMVDSCKHVKIISQLQ-QSPISPHLVLP 333
+P +N + +S Q Q + SQL+ +P +
Sbjct: 234 MNPASTGGINHTGE--LSASAARCQTDFQSNLGSAPAALAALAGSQLRTANPANRAQQQQ 291
Query: 334 QEVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVE---GLDERKLVLIGTPLATQT 390
E+ + N +G +IGKGG I +I+Q +G MI+I++ E G +R + + G P +
Sbjct: 292 HEMTVSNDLIGCIIGKGGTKIAEIRQISGAMIRISNCEEREGGNTDRTITISGNPDSVAL 351
Query: 391 AIMMINNRIDMD 402
A +IN RI M+
Sbjct: 352 AQYLINMRISME 363
>Hs14141168 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 366
Score = 106 bits (264), Expect = 7e-23
Identities = 88/365 (24%), Positives = 171/365 (46%), Gaps = 28/365 (7%)
Query: 59 DSGQVPNYIN----LRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVI 114
D+G + +N +R+L K+ ++G KGE V +++ E+ RIN+S+ ER+I
Sbjct: 2 DTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG--NCPERII 59
Query: 115 FVRGKCEEVARAFGKIVRAINNESDDDSNERSL----PLVVNLLIPHHFMGCIIGRQGSR 170
+ G + +AF I+ + + + P+ + L++P G +IG+ G +
Sbjct: 60 TLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCK 119
Query: 171 LHEIEDLSAARLMASPQQLPMSNDRILSLTGVADAIHIATYYIGQTILENESKLKNK-KS 229
+ EI + + A++ + LP S +R +++ G+ +I I +LE S+ K +
Sbjct: 120 IKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVT 179
Query: 230 VFYHPGPMHSVLVNNYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRR--- 286
+ Y P P S ++ +G + TP + + + + P++ T+ +
Sbjct: 180 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPD-LEGPPLEAYTIQGQYAI 238
Query: 287 TKPPVSK-YPIGPQQSLQP-------YTDMVDSCKHVK-IISQLQQSPISPHLVLPQEVF 337
+P ++K + + QQS P ++ + S VK + L S E+
Sbjct: 239 PQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASA----QTTSHELT 294
Query: 338 IDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVEGLDERKLVLIGTPLATQTAIMMINN 397
I N +G +IG+ G I +I+Q +G IKI +PVEG +R++ + G+ + A +IN
Sbjct: 295 IPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINV 354
Query: 398 RIDMD 402
R+ +
Sbjct: 355 RLSSE 359
>Hs14670369 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 403
Score = 105 bits (263), Expect = 1e-22
Identities = 84/342 (24%), Positives = 148/342 (42%), Gaps = 51/342 (14%)
Query: 67 INLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRGKCEEVARA 126
+ LRML K+ ++G KGE V RI+ +++ RI +S+ ER+ + G V A
Sbjct: 18 LTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG--SCPERITTITGSTAAVFHA 75
Query: 127 FGKIVRAINNE----SDDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIEDLSAARL 182
I ++ + + N P+ + L+IP G +IG+ G+++ EI + + A++
Sbjct: 76 VSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQV 135
Query: 183 MASPQQLPMSNDRILSLTGVADAIHIATYYIGQTILENESKLKNKKSVFYHPG-PMHSVL 241
+ LP S +R ++++GV DAI + I ILE+ K ++ YHP + +VL
Sbjct: 136 QVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPK---GATIPYHPSLSLGTVL 192
Query: 242 VNNYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRRTKPPVSKYPIGPQQS 301
++ Q + + P ++T + + + T V G Q S
Sbjct: 193 LSANQGFSVQGQYGAVTPAEVTKL----------QQLSSHAVPFATPSVVPGLDPGTQTS 242
Query: 302 LQPYTDMVDSCKHVKIISQLQQSPISPHLVLPQEVFIDNKFVGNVIGKGGKNIQQIKQST 361
QE + N +G VIG+ G I +I+Q +
Sbjct: 243 -------------------------------SQEFLVPNDLIGCVIGRQGSKISEIRQMS 271
Query: 362 GCMIKINDPVEGLDERKLVLIGTPLATQTAIMMINNRIDMDK 403
G IKI + EG ER + + G+P++ A +I ++ K
Sbjct: 272 GAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAK 313
>Hs14141166 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 362
Score = 105 bits (262), Expect = 1e-22
Identities = 87/364 (23%), Positives = 170/364 (45%), Gaps = 30/364 (8%)
Query: 59 DSGQVPNYIN----LRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVI 114
D+G + +N +R+L K+ ++G KGE V +++ E+ RIN+S+ ER+I
Sbjct: 2 DTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG--NCPERII 59
Query: 115 FVRGKCEEVARAFGKIVRAINNESDDDSNERSL----PLVVNLLIPHHFMGCIIGRQGSR 170
+ G + +AF I+ + + + P+ + L++P G +IG+ G +
Sbjct: 60 TLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCK 119
Query: 171 LHEIEDLSAARLMASPQQLPMSNDRILSLTGVADAIHIATYYIGQTILENESKLKNKKSV 230
+ EI + + A++ + LP S +R +++ G+ +I I +LE+ K ++
Sbjct: 120 IKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPK---GVTI 176
Query: 231 FYHPGPMHSVLVNNYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRR---T 287
Y P P S ++ +G + TP + + + + P++ T+ +
Sbjct: 177 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPD-LEGPPLEAYTIQGQYAIP 235
Query: 288 KPPVSK-YPIGPQQSLQP-------YTDMVDSCKHVK-IISQLQQSPISPHLVLPQEVFI 338
+P ++K + + QQS P ++ + S VK + L S E+ I
Sbjct: 236 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASA----QTTSHELTI 291
Query: 339 DNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVEGLDERKLVLIGTPLATQTAIMMINNR 398
N +G +IG+ G I +I+Q +G IKI +PVEG +R++ + G+ + A +IN R
Sbjct: 292 PNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVR 351
Query: 399 IDMD 402
+ +
Sbjct: 352 LSSE 355
>At3g04610 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 577
Score = 86.3 bits (212), Expect = 8e-17
Identities = 96/396 (24%), Positives = 156/396 (39%), Gaps = 55/396 (13%)
Query: 36 LEDNEAEP------QNSELNGDGT-HLTEKDSGQVPNYINLRMLCLMKQASKVVGGKGER 88
+ED E P Q SE D T EK P RML ++ ++G KG+
Sbjct: 149 VEDEEGIPEHLESLQKSEPEEDATVGGEEKRWPGWPGETVFRMLVPAQKVGSIIGRKGDV 208
Query: 89 VNRIKSETNTRINVSDNINGVMERVIFVRGKCEE----------VARAFGKIVRAINNES 138
+ +I ET RI + D G ER + V GK E + R +IV ++ E+
Sbjct: 209 IKKIVEETRARIKILDGPPGTTERAVMVSGKEEPESSLPPSMDGLLRVHMRIVDGLDGEA 268
Query: 139 DDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIEDLSA--ARLMASPQQLP---MSN 193
+ LL+P G +IG+QG + I++ SA R++ S + LP + +
Sbjct: 269 SQAPPPSKVS--TRLLVPASQAGSLIGKQGGTVKAIQEASACIVRVLGS-EDLPVFALQD 325
Query: 194 DRILSLTGVADAIHIATYYIGQTI------------LENESKLKNKKSVFYHPGPMHSVL 241
DR++ + G ++H A I + EN+ + K + + + P P S
Sbjct: 326 DRVVEVVGEPTSVHRALELIASHLRKFLVDRSIIPFFENQMQ-KPTRQMDHMPPPHQSWG 384
Query: 242 VNNYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRRTKPPVSKYPIGPQQS 301
+ GG NP P + P H Y+P + +PP+ K P Q
Sbjct: 385 PPQGHAPSVGGGGYGHNP---PPYMQPPPRHDSYYPPPE-----MRQPPMEKQ---PHQG 433
Query: 302 LQPYTDMVDSCKHVKIISQLQQSPISPHLVLPQEVFIDNKFVGNVIGKGGKNIQQIKQST 361
+ Y HV + ++ + +P + VIG G NI ++ +
Sbjct: 434 ISAYGREPPMNVHVSSAPPMVAQQVTQQMQIPL------SYADAVIGTSGSNISYTRRLS 487
Query: 362 GCMIKINDPVEGLDERKLVLIGTPLATQTAIMMINN 397
G + I + E + + GT QTA+ +I N
Sbjct: 488 GATVTIQETRGVPGEMTVEVSGTGSQVQTAVQLIQN 523
>Hs14670371 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 369
Score = 82.8 bits (203), Expect = 9e-16
Identities = 72/314 (22%), Positives = 131/314 (40%), Gaps = 51/314 (16%)
Query: 95 ETNTRINVSDNINGVMERVIFVRGKCEEVARAFGKIVRAINNE----SDDDSNERSLPLV 150
+++ RI +S+ ER+ + G V A I ++ + + N P+
Sbjct: 12 QSSARITISEG--SCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVT 69
Query: 151 VNLLIPHHFMGCIIGRQGSRLHEIEDLSAARLMASPQQLPMSNDRILSLTGVADAIHIAT 210
+ L+IP G +IG+ G+++ EI + + A++ + LP S +R ++++GV DAI +
Sbjct: 70 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCV 129
Query: 211 YYIGQTILENESKLKNKKSVFYHPG-PMHSVLVNNYQMYMIYSGGAPTNPQDITPMVAPH 269
I ILE+ K ++ YHP + +VL++ Q + + P ++T +
Sbjct: 130 RQICAVILESPPK---GATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKL---- 182
Query: 270 QEHHQYHPMDKKTMNRRTKPPVSKYPIGPQQSLQPYTDMVDSCKHVKIISQLQQSPISPH 329
+ + T V G Q S
Sbjct: 183 ------QQLSSHAVPFATPSVVPGLDPGTQTS---------------------------- 208
Query: 330 LVLPQEVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVEGLDERKLVLIGTPLATQ 389
QE + N +G VIG+ G I +I+Q +G IKI + EG ER + + G+P++
Sbjct: 209 ---SQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIA 265
Query: 390 TAIMMINNRIDMDK 403
A +I ++ K
Sbjct: 266 LAQYLITACLETAK 279
>CE27461 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 451
Score = 77.8 bits (190), Expect = 3e-14
Identities = 38/147 (25%), Positives = 84/147 (56%), Gaps = 11/147 (7%)
Query: 67 INLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRGKCEEVARA 126
+ +R+L K+ ++G KG+++ +I+ E+ +IN+SD ER++ + G + +A
Sbjct: 72 LTIRLLMQGKEVGSIIGKKGDQIKKIREESGAKINISDG--SCPERIVTITGTLGVIGKA 129
Query: 127 FGKIVRAINNESDDD-----SNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIEDLSAAR 181
F + N+ ++D ++ P+ + +++P G +IG+ GS++ +I + + A
Sbjct: 130 FNMVC----NKFEEDMLLLPNSVPKPPITMRVIVPATQCGSLIGKGGSKIKDIREATGAS 185
Query: 182 LMASPQQLPMSNDRILSLTGVADAIHI 208
+ + + LP S +R ++L+G ADAI++
Sbjct: 186 IQVASEMLPHSTERAVTLSGTADAINL 212
>YBL032w [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 381
Score = 72.8 bits (177), Expect = 9e-13
Identities = 50/199 (25%), Positives = 94/199 (47%), Gaps = 32/199 (16%)
Query: 67 INLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRGKCEEVARA 126
IN R+L +K+A+K++G KG ++RI++ +I +S+ + G +R++ G VA A
Sbjct: 44 INHRLLLSLKEAAKIIGTKGSTISRIRAANAVKIGISEKVPGCSDRILSCAGNVINVANA 103
Query: 127 FGKIVRAIN--NESDDDSNE-------------RSLPL----------------VVNLLI 155
G IV +N N ++D+ E LP V L++
Sbjct: 104 IGDIVDVLNKRNPENEDAAEGEAEEHYYFHFLNHILPAPSKDEIRDLQQLEDIGYVRLIV 163
Query: 156 PHHFMGCIIGRQGSRLHEIEDLSAARLMASPQQLPMSNDRILSLTGVADAIHIATYYIGQ 215
+ + IIG+ G+ + + + +++AS LP S++RI+ + G +I I +
Sbjct: 164 ANSHISSIIGKAGATIKSLINKHGVKIVASKDFLPASDERIIEIQGFPGSITNVLIEISE 223
Query: 216 TILEN-ESKLKNKKSVFYH 233
IL + + + ++S F H
Sbjct: 224 IILSDVDVRFSTERSYFPH 242
>At1g14170 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 479
Score = 69.7 bits (169), Expect = 8e-12
Identities = 81/390 (20%), Positives = 155/390 (38%), Gaps = 59/390 (15%)
Query: 70 RMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRGKCEEVARAFGK 129
R LC +K+ ++G GE +I+SET + + +++ + G ERV+ + EE+ FG
Sbjct: 47 RYLCPVKKTGSIIGKGGEIAKQIRSETKSNMRINEALPGCEERVVTMYSTNEEL-NHFGD 105
Query: 130 -------------------IVRAINNESDDDSNE--RSLPLVVNLLIPHHFMGCIIGRQG 168
+ A ++ DD N+ + V +L+P +GC+IG+ G
Sbjct: 106 DGELVCPALDALFKVHDMVVADADQDDGTDDDNDLGEKQTVTVRMLVPSDQIGCVIGKGG 165
Query: 169 SRLHEIEDLSAARLMASPQQLP-----MSNDRILSLTGVADAIHIATYYIGQTILENESK 223
+ + + + A++ LP +S+D +L + G + A Y + + +N S+
Sbjct: 166 QVIQNLRNDTNAQIRVIKDHLPACALTLSHDELLLIIGEPLVVREALYQVASLLHDNPSR 225
Query: 224 -----LKNKKSVFYHPGP--MHSVLVNNYQMYMIYSGGAPTNPQDITPMVAPHQE----- 271
L + S + PG M + L ++++ Y + A + + P +
Sbjct: 226 FQHLLLSSSSSSMHQPGAMLMSAALTSSHRNYAVRRDIADAR-EFCVCFICPAENVGGVI 284
Query: 272 ------HHQYHPMDKKTMNRRTKPPVSKYPIGPQQSLQPYTDMVDSCKHVKIISQLQQSP 325
+Q T+ T I S + Y D + + Q
Sbjct: 285 GKGGGFINQIRQETGATIRVNTSETDDDDCIIFISSKEFYEDQSPAVNAAIRLQQRCSEK 344
Query: 326 I---SPHLVLPQEVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKIND-----PVEGLDER 377
+ + L + + + + +G +IGKGG I +++ T I+I + DE
Sbjct: 345 VGKDANDLAISTRLLVSSSQIGCLIGKGGAVISEMRSVTRANIRILQKEDVPKIAREDEE 404
Query: 378 KLVLIGTPLA-----TQTAIMMINNRIDMD 402
+ + G+P A TQ + + N DMD
Sbjct: 405 MVQITGSPDAAMKALTQVILRLRANSFDMD 434
>At5g15270 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 568
Score = 65.1 bits (157), Expect = 2e-10
Identities = 73/329 (22%), Positives = 135/329 (40%), Gaps = 76/329 (23%)
Query: 70 RMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRGKCEEVARAFGK 129
R LC +K+ V+G G+ V +++++T ++I + + I G ERVI + +E AFG
Sbjct: 53 RYLCPVKKIGSVIGRGGDIVKQLRNDTRSKIRIGEAIPGCDERVITIYSPSDE-TNAFGD 111
Query: 130 IVRAINNESD----------------DDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHE 173
+ ++ D +DS E + LL+P +GCI+GR G +
Sbjct: 112 GEKVLSPAQDALFRIHDRVVADDARSEDSPEGEKQVTAKLLVPSDQIGCILGRGGQIVQN 171
Query: 174 IEDLSAARL-MASPQQLP---MSNDRILSLTGVADAIHIATYYIGQTILENESKLKN--K 227
I + A++ + + +P +++D ++ ++G + A I + EN S+ +N
Sbjct: 172 IRSETGAQIRIVKDRNMPLCALNSDELIQISGEVLIVKKALLQIASRLHENPSRSQNLLS 231
Query: 228 KSVFYHPGPMHSVLVNNYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRRT 287
S Y G + M ++GG + P++ + D +R
Sbjct: 232 SSGGYPAGSL-----------MSHAGG--PRLVGLAPLMGSYGR-------DAGDWSRPL 271
Query: 288 KPPVSKYPIGPQQSLQPYTDMVDSCKHVKIISQLQQSPISPHLVLPQEVFIDNKFVGNVI 347
P P P T+ ++++S ++ + +VI
Sbjct: 272 YQPPRNDP--------PATEF-----FIRLVSPVEN-------------------IASVI 299
Query: 348 GKGGKNIQQIKQSTGCMIKINDP-VEGLD 375
GKGG I Q++Q T IK++ EG D
Sbjct: 300 GKGGALINQLRQETRATIKVDSSRTEGND 328
>CE09674 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnRNP contains KH
domain
Length = 397
Score = 62.0 bits (149), Expect = 2e-09
Identities = 46/164 (28%), Positives = 75/164 (45%), Gaps = 11/164 (6%)
Query: 42 EPQNSELNGDGTHLTEKDSGQVP----NYINLRMLCLMKQASKVVGGKGERVNRIKSETN 97
E N + + G H K G +R+L K A ++G GE + R+++E N
Sbjct: 21 EHDNDDGDRTGRHKRPKTDGFTEAIQQGKFEVRLLVSSKSAGAIIGKGGENIKRLRAEFN 80
Query: 98 TRINVSDNINGVMERVIFVRGKCEEVARAFGKIVRAINNESDDDSNERSLPLVVNLLIPH 157
+ V D+ ERV V + V I++ + +D+ +ER P V +L+
Sbjct: 81 AHVQVPDS--NTPERVCTVTADEKTVLN----ILKDVLPRLEDNFSERD-PCEVRMLVHQ 133
Query: 158 HFMGCIIGRQGSRLHEIEDLSAARLMASPQQLPMSNDRILSLTG 201
G +IGR GS++ E+ + +ARL P S DR+L +G
Sbjct: 134 SHAGALIGRNGSKIKELREKCSARLKIFTGCAPGSTDRVLITSG 177
>At4g26000 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 495
Score = 61.6 bits (148), Expect = 2e-09
Identities = 95/433 (21%), Positives = 164/433 (36%), Gaps = 74/433 (17%)
Query: 10 EPVSSPNSLKRKPDHETLEAGIKRVALEDN------EAEPQNSELNGDGTHLTEKDSGQV 63
+ V + S+ + + AG AL D E +S + T DS +
Sbjct: 6 DSVENNGSINLPENENLIPAGFSAAALLDENSGAFPELNQPDSLAAAETTFPDTNDSAEE 65
Query: 64 -----PNYINLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRG 118
P RM+ + + ++G KG+ + ++ ET RI V D +R++ + G
Sbjct: 66 RWPGWPGDCVFRMIVPVTKVGAIIGRKGDFIKKMCEETRARIKVLDGPVNTPDRIVLISG 125
Query: 119 K----------CEEVARAFGKIVRAINNESDDDSNERSLPLVVNLLIPHHFMGCIIGRQG 168
K + V R F ++ +N+ DD N S+ V LL+ +IG+QG
Sbjct: 126 KEEPEAYMSPAMDAVLRVFRRVSGLPDNDDDDVQNAGSVFSSVRLLVASTQAINLIGKQG 185
Query: 169 SRLHEIEDLSAARL-MASPQQLPM---SNDRILSLTGVADAI---------HIATYYIGQ 215
S + I + S A + + S ++ P ++RI+ L G A I H+ + +
Sbjct: 186 SLIKSIVENSGASVRILSEEETPFYAAQDERIVDLQGEALKILKALEAIVGHLRRFLVDH 245
Query: 216 TI--------LENESKLKNKKSVFYHPGPMHSVLVNNYQMYMIYSGGAPTNPQDITPMVA 267
T+ L S+ + ++ + +H++ N M +S A P
Sbjct: 246 TVVPLFEKQYLARVSQTRQEEPLAESKSSLHTISSN--LMEPDFSLLARREP-------- 295
Query: 268 PHQEHHQYHPMDKKTMNRRTKPPVSKYPIGPQQSLQPYTDMVD-SCKHVKIISQLQQSPI 326
+ D + +R VS Y P S + + S V +SQ Q P
Sbjct: 296 ------LFLERDSRVDSRVQPSGVSIYSQDPVLSARHSPGLARVSSAFVTQVSQTMQIPF 349
Query: 327 SPHLVLPQEVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVEGLDERKLVLIGTPL 386
S + ++IG G NI I++ +G I I + D+ + + GT
Sbjct: 350 S--------------YAEDIIGVEGANIAYIRRRSGATITIKESPHP-DQITVEIKGTTS 394
Query: 387 ATQTAIMMINNRI 399
QTA +I I
Sbjct: 395 QVQTAEQLIQEFI 407
>Hs20539507 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains RRM and KH
domains
Length = 579
Score = 60.8 bits (146), Expect = 4e-09
Identities = 79/333 (23%), Positives = 138/333 (40%), Gaps = 64/333 (19%)
Query: 60 SGQVPNYINLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNIN-GVMERVIFVRG 118
S Q P + LR+L + ++G +G + I +T ++I+V N G E+ I +
Sbjct: 189 SKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILS 248
Query: 119 KCEEVARAFGKIVRAINNESDDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIEDLS 178
E + A I+ ++ E+ D +PL +L ++F+G +IG++G L +IE +
Sbjct: 249 TPEGTSAACKSILEIMHKEAQDIKFTEEIPL--KILAHNNFVGRLIGKEGRNLKKIEQDT 306
Query: 179 AARLMASP-QQLPMSN-DRILSLTGVADAIHIATYYIGQTILENESKLKNKKSVFYHPGP 236
++ SP Q+L + N +R +++ G +T + E ++ K Y
Sbjct: 307 DTKITISPLQELTLYNPERTITVKGNV-----------ETCAKAEEEIMKKIRESYE--- 352
Query: 237 MHSVLVNNYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRRTKPPVSKYPI 296
+ + N Q ++I G N + P + PP S
Sbjct: 353 -NDIASMNLQAHLI--PGLNLNALGLFPPTS------------------GMPPPTS---- 387
Query: 297 GPQQSLQPYTDMVDSCKHVKIISQLQQSPISPHLVLPQEVFIDNKFVGNVIGKGGKNIQQ 356
GP ++ P Q +QS +FI VG +IGK G++I+Q
Sbjct: 388 GPPSAMTP------------PYPQFEQSETE-----TVHLFIPALSVGAIIGKQGQHIKQ 430
Query: 357 IKQSTGCMIKINDPVEGLDE--RKLVLIGTPLA 387
+ + G IKI P E D R +++ G P A
Sbjct: 431 LSRFAGASIKI-APAEAPDAKVRMVIITGPPEA 462
>Hs14740532 [A] KOG1676 K-homology type RNA binding proteins
Length = 572
Score = 60.5 bits (145), Expect = 5e-09
Identities = 41/154 (26%), Positives = 76/154 (48%), Gaps = 12/154 (7%)
Query: 76 KQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRG---KCEEVARAFGKIVR 132
K ++G GE+++RI++E+ +I ++ +G+ ER + G E+ R G+IV
Sbjct: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
Query: 133 AINN----ESDDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIEDLSAARL-MASPQ 187
N +D DSN + +LIP +G +IGR G + ++++ + ++ M
Sbjct: 147 RCRNGPGFHNDIDSNS----TIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDG 202
Query: 188 QLPMSNDRILSLTGVADAIHIATYYIGQTILENE 221
LP D+ L +TG A + A + + I E +
Sbjct: 203 PLPTGADKPLRITGDAFKVQQAREMVLEIIREKD 236
Score = 53.5 bits (127), Expect = 6e-07
Identities = 25/70 (35%), Positives = 42/70 (59%)
Query: 331 VLPQEVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVEGLDERKLVLIGTPLATQT 390
V+ +E + +K VG +IG+GG+ I +I+ +GC I+I G+ ER VL GTP + +
Sbjct: 77 VITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQ 136
Query: 391 AIMMINNRID 400
A ++ +D
Sbjct: 137 AKRLLGQIVD 146
>Hs5729901 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains RRM and KH
domains
Length = 579
Score = 59.7 bits (143), Expect = 8e-09
Identities = 79/333 (23%), Positives = 137/333 (40%), Gaps = 64/333 (19%)
Query: 60 SGQVPNYINLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNIN-GVMERVIFVRG 118
S Q P + LR+L + ++G +G + I +T ++I+V N G E+ I +
Sbjct: 189 SKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILS 248
Query: 119 KCEEVARAFGKIVRAINNESDDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIEDLS 178
E + A I+ ++ E+ D +PL +L ++F+G +IG++G L +IE +
Sbjct: 249 TPEGTSAACKSILEIMHKEAQDIKFTEEIPL--KILAHNNFVGRLIGKEGRNLKKIEQDT 306
Query: 179 AARLMASP-QQLPMSN-DRILSLTGVADAIHIATYYIGQTILENESKLKNKKSVFYHPGP 236
++ SP Q+L + N +R +++ G +T + E ++ K Y
Sbjct: 307 DTKITISPLQELTLYNPERTITVKGNV-----------ETCAKAEEEIMKKIRESYE--- 352
Query: 237 MHSVLVNNYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRRTKPPVSKYPI 296
+ + N Q ++I G N + P + PP S
Sbjct: 353 -NDIASMNLQAHLI--PGLNLNALGLFPPTS------------------GMPPPTS---- 387
Query: 297 GPQQSLQPYTDMVDSCKHVKIISQLQQSPISPHLVLPQEVFIDNKFVGNVIGKGGKNIQQ 356
GP ++ P Q +QS FI VG +IGK G++I+Q
Sbjct: 388 GPPSAMTP------------PYPQFEQSETE-----TVHQFIPALSVGAIIGKQGQHIKQ 430
Query: 357 IKQSTGCMIKINDPVEGLDE--RKLVLIGTPLA 387
+ + G IKI P E D R +++ G P A
Sbjct: 431 LSRFAGASIKI-APAEAPDAKVRMVIITGPPEA 462
>At5g04430 [AR] KOG2191 RNA-binding protein NOVA1/PASILLA and related KH
domain proteins
Length = 313
Score = 58.9 bits (141), Expect = 1e-08
Identities = 48/191 (25%), Positives = 89/191 (46%), Gaps = 8/191 (4%)
Query: 56 TEKDSGQVPNYINLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDN---INGVMER 112
+E DS + P +I R L A V+G G + ++++ RI +S N G +R
Sbjct: 26 SEADSAEKPTHI--RFLVSNAAAGSVIGKGGSTITEFQAKSGARIQLSRNQEFFPGTTDR 83
Query: 113 VIFVRGKCEEVARAFGKIVRAINNESD-DDSNERSLPLVVNLLIPHHFMGCIIGRQGSRL 171
+I + G +EV I+ +++E +D NE + L++P+ G IIG+ G+ +
Sbjct: 84 IIMISGSIKEVVNGLELILDKLHSELHAEDGNEVEPRRRIRLVVPNSSCGGIIGKGGATI 143
Query: 172 HEIEDLSAARLMASPQQLPM--SNDRILSLTGVADAIHIATYYIGQTILENESKLKNKKS 229
+ S A + SP +DR+++L+G + A I + E++ +N S
Sbjct: 144 KSFIEESKAGIKISPLDNTFYGLSDRLVTLSGTFEEQMRAIDLILAKLTEDDHYSQNVHS 203
Query: 230 VFYHPGPMHSV 240
+ + +SV
Sbjct: 204 PYSYAAGYNSV 214
>HsM5729882 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains RRM and KH
domains
Length = 577
Score = 57.8 bits (138), Expect = 3e-08
Identities = 70/326 (21%), Positives = 127/326 (38%), Gaps = 61/326 (18%)
Query: 67 INLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNIN-GVMERVIFVRGKCEEVAR 125
I LR+L + ++G +G + I +T ++I+V N G E+ I V E +
Sbjct: 196 IPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSS 255
Query: 126 AFGKIVRAINNESDDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIE-DLSAARLMA 184
A I+ ++ E+ D +PL +L ++F+G +IG++G L ++E D ++
Sbjct: 256 ACKMILEIMHKEAKDTKTADEVPL--KILAHNNFVGRLIGKEGRNLKKVEQDTETKITIS 313
Query: 185 SPQQLPMSN-DRILSLTGVADAIHIATYYIGQTILENESKLKNKKSVFYHPGPMHSVLVN 243
S Q L + N +R +++ G + A I + + E S+ H P + +
Sbjct: 314 SLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIP--GLNLA 371
Query: 244 NYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRRTKPPVSKYPIGPQQSLQ 303
++ S P P +T P S + P+Q +
Sbjct: 372 AVGLFPASSSAVPPPPSSVTGAA-----------------------PYSSFMQAPEQEM- 407
Query: 304 PYTDMVDSCKHVKIISQLQQSPISPHLVLPQEVFIDNKFVGNVIGKGGKNIQQIKQSTGC 363
+VFI + VG +IGK G++I+Q+ +
Sbjct: 408 ------------------------------VQVFIPAQAVGAIIGKKGQHIKQLSRFASA 437
Query: 364 MIKINDPVEGLDERKLVLIGTPLATQ 389
IKI P + ++V+I P Q
Sbjct: 438 SIKIAPPETPDSKVRMVIITGPPEAQ 463
>Hs21361352 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains RRM and KH
domains
Length = 577
Score = 57.4 bits (137), Expect = 4e-08
Identities = 70/326 (21%), Positives = 126/326 (38%), Gaps = 61/326 (18%)
Query: 67 INLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNIN-GVMERVIFVRGKCEEVAR 125
I LR+L + ++G +G + I +T ++I+V N G E+ I V E +
Sbjct: 196 IPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSS 255
Query: 126 AFGKIVRAINNESDDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIE-DLSAARLMA 184
A I+ ++ E+ D +PL L ++F+G +IG++G L ++E D ++
Sbjct: 256 ACKMILEIMHKEAKDTKTADEVPL--KTLAHNNFVGRLIGKEGRNLKKVEQDTETKITIS 313
Query: 185 SPQQLPMSN-DRILSLTGVADAIHIATYYIGQTILENESKLKNKKSVFYHPGPMHSVLVN 243
S Q L + N +R +++ G + A I + + E S+ H P + +
Sbjct: 314 SLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLTP--GLNLA 371
Query: 244 NYQMYMIYSGGAPTNPQDITPMVAPHQEHHQYHPMDKKTMNRRTKPPVSKYPIGPQQSLQ 303
++ S P P +T P S + P+Q +
Sbjct: 372 AVGLFPASSSAVPPPPSSVTGAA-----------------------PYSSFMQAPEQEM- 407
Query: 304 PYTDMVDSCKHVKIISQLQQSPISPHLVLPQEVFIDNKFVGNVIGKGGKNIQQIKQSTGC 363
+VFI + VG +IGK G++I+Q+ +
Sbjct: 408 ------------------------------VQVFIPAQAVGAIIGKKGQHIKQLSRFASA 437
Query: 364 MIKINDPVEGLDERKLVLIGTPLATQ 389
IKI P + ++V+I P Q
Sbjct: 438 SIKIAPPETPDSKVRMVIITGPPEAQ 463
>Hs4504865 [A] KOG1676 K-homology type RNA binding proteins
Length = 711
Score = 55.5 bits (132), Expect = 1e-07
Identities = 29/81 (35%), Positives = 47/81 (57%)
Query: 317 IISQLQQSPISPHLVLPQEVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVEGLDE 376
I SQL P + +E + + VG +IG+GG+ I +I+Q +GC ++I+ GL E
Sbjct: 130 ISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPE 189
Query: 377 RKLVLIGTPLATQTAIMMINN 397
R + L G P + Q A MM+++
Sbjct: 190 RSVSLTGAPESVQKAKMMLDD 210
>Hs14165437 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnRNP contains KH
domain
Length = 464
Score = 55.5 bits (132), Expect = 1e-07
Identities = 24/69 (34%), Positives = 43/69 (61%)
Query: 331 VLPQEVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVEGLDERKLVLIGTPLATQT 390
++ +V I G++IGKGG+ I+QI+ +G IKI++P+EG ++R + + GT Q
Sbjct: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQN 446
Query: 391 AIMMINNRI 399
A ++ N +
Sbjct: 447 AQYLLQNSV 455
>Hs14165435 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnRNP contains KH
domain
Length = 463
Score = 55.5 bits (132), Expect = 1e-07
Identities = 24/69 (34%), Positives = 43/69 (61%)
Query: 331 VLPQEVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVEGLDERKLVLIGTPLATQT 390
++ +V I G++IGKGG+ I+QI+ +G IKI++P+EG ++R + + GT Q
Sbjct: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQN 446
Query: 391 AIMMINNRI 399
A ++ N +
Sbjct: 447 AQYLLQNSV 455
>Hs5729884 [AR] KOG2193 IGF-II mRNA-binding protein IMP contains RRM and KH
domains
Length = 556
Score = 55.1 bits (131), Expect = 2e-07
Identities = 42/177 (23%), Positives = 83/177 (46%), Gaps = 28/177 (15%)
Query: 57 EKDSGQVPNYINLRMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVM---ERV 113
E D ++ I L++L +++G +G + +I+ ET T+I +S + + ER
Sbjct: 265 EADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERT 324
Query: 114 IFVRGKCEEVARAFGKIVRAINNESDDDS-----------------------NERSLPL- 149
I V+G E A A +I++ + ++D + S P
Sbjct: 325 ITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQ 384
Query: 150 -VVNLLIPHHFMGCIIGRQGSRLHEIEDLSAARLMASPQQLPMSNDRILSLTGVADA 205
+VNL IP +G IIG++G+ + ++ + A + +P + P ++R++ +TG +A
Sbjct: 385 EIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
>At5g64390 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 833
Score = 53.5 bits (127), Expect = 6e-07
Identities = 44/178 (24%), Positives = 82/178 (45%), Gaps = 20/178 (11%)
Query: 70 RMLCLMKQASKVVGGKGERVNRIKSETNTRINVSDNINGVMERVIFVRG----KCEE--- 122
++LC + A V+G G+ V + SET INV + ++ ER+I V +C+
Sbjct: 455 KILCSTENAGGVIGTGGKVVRMLHSETGAFINVGNTLDDCEERLIAVTASENPECQSSPA 514
Query: 123 ---VARAFGKIVRAINNESDDDSNERSLPLVVNLLIPHHFMGCIIGRQGSRLHEIEDLSA 179
+ F ++ N+ D+ S + L++P +GC++G+ G + E+ +
Sbjct: 515 QKAIMLIFSRLFELATNKILDNGPRSS--ITARLVVPTSQIGCVLGKGGVIVSEMRKTTG 572
Query: 180 ARL-MASPQQLP---MSNDRILSLTG----VADAIHIATYYIGQTILENESKLKNKKS 229
A + + +Q P ND+++ +TG V +AI T + ++ N K KS
Sbjct: 573 AAIQILKVEQNPKCISENDQVVQITGEFPNVREAIFHITSRLRDSVFSNSMKNSLAKS 630
>Hs17402900 [A] KOG1676 K-homology type RNA binding proteins
Length = 644
Score = 53.1 bits (126), Expect = 7e-07
Identities = 25/70 (35%), Positives = 44/70 (62%)
Query: 331 VLPQEVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVEGLDERKLVLIGTPLATQT 390
V+ +E + + VG +IG+GG+ I +I+Q +GC I+I GL ER +L GTP + Q+
Sbjct: 100 VMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQS 159
Query: 391 AIMMINNRID 400
A +++ ++
Sbjct: 160 AKRLLDQIVE 169
>Hs6031187 [AR] KOG2191 RNA-binding protein NOVA1/PASILLA and related KH
domain proteins
Length = 486
Score = 52.8 bits (125), Expect = 1e-06
Identities = 28/78 (35%), Positives = 44/78 (55%), Gaps = 3/78 (3%)
Query: 335 EVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKIN---DPVEGLDERKLVLIGTPLATQTA 391
E+ + VG ++GKGGK + + ++ TG I+I+ + V G RK+ + GTP ATQ A
Sbjct: 404 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 463
Query: 392 IMMINNRIDMDKRKRQEN 409
+I RI ++ R N
Sbjct: 464 QYLITQRITYEQGVRAAN 481
>Hs4505425 [AR] KOG2191 RNA-binding protein NOVA1/PASILLA and related KH
domain proteins
Length = 510
Score = 52.8 bits (125), Expect = 1e-06
Identities = 28/78 (35%), Positives = 44/78 (55%), Gaps = 3/78 (3%)
Query: 335 EVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKIN---DPVEGLDERKLVLIGTPLATQTA 391
E+ + VG ++GKGGK + + ++ TG I+I+ + V G RK+ + GTP ATQ A
Sbjct: 428 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 487
Query: 392 IMMINNRIDMDKRKRQEN 409
+I RI ++ R N
Sbjct: 488 QYLITQRITYEQGVRAAN 505
>Hs18560043 [AR] KOG2192 PolyC-binding hnRNP-K protein HRB57A/hnRNP contains KH
domain
Length = 161
Score = 50.8 bits (120), Expect = 4e-06
Identities = 23/65 (35%), Positives = 39/65 (59%)
Query: 335 EVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVEGLDERKLVLIGTPLATQTAIMM 394
+V I G++IGKGG+ I+QI G IKI++P+EG +++ ++ GT Q A +
Sbjct: 97 QVTIPKDLTGSIIGKGGQRIKQIGHELGASIKIDEPLEGSEDQITIITGTQDQIQNAQYL 156
Query: 395 INNRI 399
+ N +
Sbjct: 157 LQNNV 161
>Hs5902724 [AR] KOG2191 RNA-binding protein NOVA1/PASILLA and related KH
domain proteins
Length = 492
Score = 50.1 bits (118), Expect = 6e-06
Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 3/78 (3%)
Query: 335 EVFIDNKFVGNVIGKGGKNIQQIKQSTGCMIKINDPVE---GLDERKLVLIGTPLATQTA 391
E+ + VG ++GKGGK + + ++ TG I+I+ E G R++ + G+P ATQ A
Sbjct: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
Query: 392 IMMINNRIDMDKRKRQEN 409
+I+ R+ ++ R N
Sbjct: 470 QYLISQRVTYEQGVRASN 487
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.134 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,825,872
Number of Sequences: 60738
Number of extensions: 1147653
Number of successful extensions: 3579
Number of sequences better than 1.0e-05: 32
Number of HSP's better than 0.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 3393
Number of HSP's gapped (non-prelim): 179
length of query: 417
length of database: 30,389,216
effective HSP length: 109
effective length of query: 308
effective length of database: 23,768,774
effective search space: 7320782392
effective search space used: 7320782392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)