ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2852 normal TZ KOG1922 Cytoskeleton Rho GTPase effector BNI1 and related formins
r_klactVI2852 normal TZ KOG1922 Signal transduction mechanisms Rho GTPase effector BNI1 and related formins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2852 1003827 1007675 1283
(1283 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL159w [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 399 e-110
YNL271c [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 282 2e-75
SPAC1F5.04c [TZ] KOG1922 Rho GTPase effector BNI1 and related fo... 173 1e-42
SPAC20G4.02c [TZ] KOG1922 Rho GTPase effector BNI1 and related f... 149 4e-35
SPCC895.05 [TZ] KOG1922 Rho GTPase effector BNI1 and related for... 126 3e-28
Hs21071077 [TZ] KOG1922 Rho GTPase effector BNI1 and related for... 104 8e-22
Hs22060175 [TZ] KOG1922 Rho GTPase effector BNI1 and related for... 94 2e-18
7298710 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 83 3e-15
Hs5803003 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 82 5e-15
Hs6382071 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 82 7e-15
Hs20535708 [TZ] KOG1923 Rac1 GTPase effector FRL 79 4e-14
Hs20550654 [TZ] KOG1923 Rac1 GTPase effector FRL 77 2e-13
Hs5174401 [TZ] KOG1923 Rac1 GTPase effector FRL 73 3e-12
Hs13569895 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 73 3e-12
Hs4885183 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous 71 1e-11
CE23783 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 71 1e-11
7294416 [TZ] KOG1923 Rac1 GTPase effector FRL 70 3e-11
7290137 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 69 6e-11
At5g07770 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 66 4e-10
CE27278 [TZ] KOG1923 Rac1 GTPase effector FRL 62 4e-09
Hs20533991 [TZ] KOG1922 Rho GTPase effector BNI1 and related for... 58 8e-08
At5g07780 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 56 4e-07
7295293 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 55 5e-07
At5g07760 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins 54 1e-06
Hs13399326 [TZ] KOG1925 Rac1 GTPase effector FHOS 54 2e-06
>YIL159w [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1375
Score = 399 bits (1024), Expect = e-110
Identities = 223/519 (42%), Positives = 309/519 (58%), Gaps = 29/519 (5%)
Query: 788 NNVTFVSKPKPEVKPLKQIHWDKIEDISDTLWNEPTTRSDLKEDLNEKGVFNEIVNLFEQ 847
N T KP P K LKQIHWDK+EDI DTLW + R + ++L G+F++I ++F+
Sbjct: 863 NPTTTDLKPPPTEKRLKQIHWDKVEDIKDTLWEDTFQRQETIKELQTDGIFSQIEDIFKM 922
Query: 848 K-----AVRMKKKSNVTASKKN-------EKVSLLSRDLAQQFGINLHMFSSYSVEDLLI 895
K A + +S++ S N +K+S LSRDLAQQFGINLHMFS S + ++
Sbjct: 923 KSPTKIANKRNAESSIALSSNNGKSSNELKKISFLSRDLAQQFGINLHMFSQLSDMEFVM 982
Query: 896 KVLRCDDDIIKNHSVLEFFNKDDFETIPQSIIRSFEPYASDWKTGKAPKEDVSKLERADR 955
KVL CD+DI++N ++L+FF K++ IP+S++ +EPY S K GKA VS L+RADR
Sbjct: 983 KVLNCDNDIVQNVNILKFFCKEELVNIPKSMLNKYEPY-SQGKDGKA----VSDLQRADR 1037
Query: 956 IYLEMFYNMRYYWKIRSSSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIV 1015
I+LE+ N+R+YW RS SLL TYE+DYYD++++LQKIDD S + S + K +I+
Sbjct: 1038 IFLELCINLRFYWNARSKSLLTLSTYERDYYDLIFKLQKIDDAISHLNRSPKFKSLMFII 1097
Query: 1016 VEIGNFMNNKKTQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNR 1075
EIGN MN + +GIKL SL KL+ V+++ D+N+SFLH IE++IR KYPDIY F DL
Sbjct: 1098 TEIGNHMNKRIVKGIKLKSLTKLAFVRSSIDQNVSFLHFIEKVIRIKYPDIYGFVDDLKN 1157
Query: 1076 LSDLGXXXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVR 1135
+ DLG + F+ GKLS E P D+ KK+ K+ A
Sbjct: 1158 IEDLGKISLEHVESECHEFHKKIEDLVTQFQVGKLSKEENLDPRDQIIKKVKFKINRAKT 1217
Query: 1136 KAELLHNQCKLTMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREAM 1195
K+ELL QCKLT+ D N MKY GEDP + E+KN FF+ F EFL +F K ++EN E+E M
Sbjct: 1218 KSELLIGQCKLTLIDLNKLMKYYGEDPKDKESKNEFFQPFIEFLAMFKKCAKENIEKEEM 1277
Query: 1196 NRVHEQRQQLLQKASTETQVEKSADDEAA-----DTIDILIKKLRSV--DPQQTIPGSSV 1248
RV+EQR+ LL ++ + +D+ D +D+LI KLR V DP+ S
Sbjct: 1278 ERVYEQRKSLLDMRTSSNKKSNGSDENDGEKVNRDAVDLLISKLREVKKDPEPLRRRKST 1337
Query: 1249 P----GTSSHPEKRSTPRTNRDQNLLSRAMTLKSGIQNL 1283
+ H T R + D LL R + + IQN+
Sbjct: 1338 KLNEIAINVHEGDVKT-RKDEDHVLLERTHAMLNDIQNI 1375
Score = 177 bits (449), Expect = 1e-43
Identities = 184/686 (26%), Positives = 316/686 (45%), Gaps = 91/686 (13%)
Query: 3 VDKNEKSISILFPLRSGSINAPTANAKTR-FSSNDSNDDLVIQGLNLVGTGLKPRSQTLR 61
+D + + +P RS S++A ++ R + ND LV GL LVG L+ +
Sbjct: 1 MDSSPNKKTYRYPRRSLSLHARDRVSEARKLEELNLNDGLVAAGLQLVGVALEKQGTGSH 60
Query: 62 -YMKSHNFSTPNVDSTRHVSKT---DKMCLADTQLPSEQE-IDAKFEELL-NGHAFLGTA 115
YMK NFS +V S+ VS+ +M +P + ++ F+ELL +G F G A
Sbjct: 61 IYMKQKNFSANDVSSSPMVSEEVNGSEMDFNPKCMPQDASLVERMFDELLKDGTFFWGAA 120
Query: 116 KQNLKSLSYTRKWELIQK--------EKKLHGDITMQDDSKLNTLHM---ILSNLNKRFS 164
+NL+++S RKW LI K +KK+ T N L L L + S
Sbjct: 121 YKNLQNISLRRKWLLICKIRSSNHWGKKKVTSSTTYSTHLATNELAENAHFLDGLVRNLS 180
Query: 165 -----VTQTLYQLERLLRHADFISLFVNANG--VSILNGFIDLLDKKSQYVYLCCYKALL 217
+++ LY+LE+ LR F+ LF+ +++ + L+ K+ Q+VYL C+K L+
Sbjct: 181 TGGMKLSKALYKLEKFLRKQSFLQLFLKDEIYLTTLIEKTLPLISKELQFVYLRCFKILM 240
Query: 218 NDTSARSVIFQNNDWITYVFCLLGTLTTDLRVRLLSTQIVILLTYXXXXX--XXXXXXXX 275
N+ AR + I + LL ++L+ +LLS ++++LLTY
Sbjct: 241 NNPLARIRALHSEPLIRWFTELLTDQNSNLKCQLLSMELLLLLTYVEGSTGCELIWDQLS 300
Query: 276 XCYESWIQAVEMTLRNPEDYAFNNSLILPKPKELLVDYSISTLLLVQSIQQLLPSNDLKL 335
+ W++ + L +D A ++SL L +L +DYS + LLL+ SI Q +N L
Sbjct: 301 ILFTDWLEWFDKIL--ADDIAIHSSLYL-NWNQLKIDYSTTFLLLINSILQGF-NNKTAL 356
Query: 336 ACFKRWKRAGIHRVFRLMK-----DLDSSALNQDIDLYIELELKVQDKQFK--------- 381
K+ IH ++ D +S + + I + E + D K
Sbjct: 357 EILNFLKKNNIHNTITFLELAYKDDPNSVVIMEQIKQFKSKESAIFDSMIKTTNDTNSLH 416
Query: 382 -NEFLSEISYGPQI--KSLIEYTKDTPLETPICNIIETILELV-NERTTEGSIKLFYVFN 437
+ ++ I P L+ KD+P+E PI II+++ +++ +++ SIKL + N
Sbjct: 417 PTKDIARIESEPLCLENCLLLKAKDSPVEAPINEIIQSLWKILDSQKPYSESIKLLKLIN 476
Query: 438 SILTYLCEH---TLDGSFDET-----NTEQVFMTSLDHIMDNLQSHQIAKRAMMELDEKK 489
S+L YL + + + SFDET N + VF S++ ++D+LQS +IA+RA+ E+D+
Sbjct: 477 SLLFYLIDSFQVSTNPSFDETLESAENVDYVFQDSVNKLLDSLQSDEIARRAVTEIDDLN 536
Query: 490 KEFDGIXXXXXXXXXXXXVSKGDXXXXXXXXXXXXXSREIRIEELQDRLEVVENQLKKEK 549
+ + V D ++ +E+++ ++ QLK K
Sbjct: 537 AKISHL------NEKLNLVENHDKDHLIAKLDESESLISLKTKEIEN----LKLQLKATK 586
Query: 550 KQLDLTIAHRDVAEYTPKRSVS-----------------LFETL----KEHKPLIGTQRS 588
K+LD H+ + + P + S +F+ L ++ + + +RS
Sbjct: 587 KRLDQITTHQRLYDQPPSLASSNLSIAGSIIKNNSHGNIIFQNLAKKQQQQQKISLPKRS 646
Query: 589 TSLSKSKRIASLS---TVANEKPQSK 611
TSL KSKR+ SLS T AN + +S+
Sbjct: 647 TSLLKSKRVTSLSSYLTDANNENESQ 672
>YNL271c [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1953
Score = 282 bits (722), Expect = 2e-75
Identities = 158/483 (32%), Positives = 278/483 (56%), Gaps = 36/483 (7%)
Query: 792 FVSKPKPEVKPLKQIHWDKIEDISDTLWNEPTTRSDLKEDLNEKGVFNEIVNLF---EQK 848
F P+P K LKQ+HW+K++ +++W +DL EKGV ++ F E K
Sbjct: 1348 FEKYPRPH-KKLKQLHWEKLDCTDNSIWGTGKAEK-FADDLYEKGVLADLEKAFAAREIK 1405
Query: 849 AVRMKKKSNVTASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNH 908
++ K+K ++ +K++ LSRD++QQFGINLHM+SS SV DL+ K+L CD D ++
Sbjct: 1406 SLASKRKEDL------QKITFLSRDISQQFGINLHMYSSLSVADLVKKILNCDRDFLQTP 1459
Query: 909 SVLEFFNKDDFETIPQSIIRSFEPYASDW------KTGKAPKEDVSKLERADRIYLEMFY 962
SV+EF +K + + ++ R++ PY++DW + K P++D + L+RAD+IYL++
Sbjct: 1460 SVVEFLSKSEIIEVSVNLARNYAPYSTDWEGVRNLEDAKPPEKDPNDLQRADQIYLQLMV 1519
Query: 963 NMRYYWKIRSSSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFM 1022
N+ YW R +L + +YE++Y ++L +L+K+D S ++ S+ L+ F +++ +GNFM
Sbjct: 1520 NLESYWGSRMRALTVVTSYEREYNELLAKLRKVDKAVSALQESDNLRNVFNVILAVGNFM 1579
Query: 1023 N--NKKTQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLG 1080
N +K+ QG KLS+L +L+ +K ++ +++FL+ +E+I+R YP DF +L + D+
Sbjct: 1580 NDTSKQAQGFKLSTLQRLTFIK-DTTNSMTFLNYVEKIVRLNYPSFNDFLSELEPVLDVV 1638
Query: 1081 XXXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELL 1140
+ ++ S E G LS + K HP DK K LP A +K +LL
Sbjct: 1639 KVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLIKTLPVLPEARKKGDLL 1698
Query: 1141 HNQCKLTMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREAMNRVHE 1200
++ KLT+ +F S M GED + AK +FF+ F++F+ + K +N E R++
Sbjct: 1699 EDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKKAQAQNLAAEEEERLYI 1758
Query: 1201 QRQQLL---QKASTETQVEK----------SADDEAAD---TIDILIKKLRSVDPQQTIP 1244
+ ++++ QK + E + +K + +DEA D +D L+++L++ P ++ P
Sbjct: 1759 KHKKIVEEQQKRAQEKEKQKENSNSPSSEGNEEDEAEDRRAVMDKLLEQLKNAGPAKSDP 1818
Query: 1245 GSS 1247
S+
Sbjct: 1819 SSA 1821
>SPAC1F5.04c [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1841
Score = 173 bits (439), Expect = 1e-42
Identities = 115/450 (25%), Positives = 217/450 (47%), Gaps = 32/450 (7%)
Query: 803 LKQIHWDKIED-ISDTLWNEPTTRSD-LKEDLNEKGVFNEIVNLFEQKAVRMKKKSNVTA 860
LKQ+HW+K+ + T W P+ ++ + E L+ GV +E+ F K + K
Sbjct: 990 LKQMHWEKLNSGLEFTFWTGPSDEANKILETLHTSGVLDELDESFAMKEAKTLVK----- 1044
Query: 861 SKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSVLEFFNKDDFE 920
K + +S +L + FGI+ H S + +++ +L CDD + + +EF + D
Sbjct: 1045 -KTCARTDYMSSELQKLFGIHFHKLSHKNPNEIIRMILHCDDSM---NECVEFLSSDKVL 1100
Query: 921 TIPQSIIRSFEPYASDWKTGKA---PKEDVSKLERADRIYLEMFYNMRYYWKIRSSSLLI 977
P+ + EPY DW G ++D S+L R D +Y+ + ++ YW R ++L +
Sbjct: 1101 NQPK-LKADLEPYRIDWANGGDLVNSEKDASELSRWDYLYVRLIVDLGGYWNQRMNALKV 1159
Query: 978 ALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMNN--KKTQGIKLSSL 1035
E +Y +++ Q + I +++S K Y+++ +GN+MN+ ++ +G + SL
Sbjct: 1160 KNIIETNYENLVRQTKLIGRAALELRDSKVFKGLLYLILYLGNYMNDYVRQAKGFAIGSL 1219
Query: 1036 NKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXXXXXXXXXXXX 1095
+L ++K N++ S LH+++ IR+ +P +F+ +L+ +++
Sbjct: 1220 QRLPLIK-NANNTKSLLHILDITIRKHFPQFDNFSPELSTVTEAAKLNIEAIEQECSELI 1278
Query: 1096 XXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLHNQCKLTMNDFNSTM 1155
++ + G LS HPDDK I L +K + L + N+ M
Sbjct: 1279 RGCQNLQIDCDSGALSDPTVFHPDDKILSVILPWLMEGTKKMDFLKEHLRTMNTTLNNAM 1338
Query: 1156 KYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQEN---KEREA-----MNRVHEQRQQLLQ 1207
+Y GE P + +KN FF+ F+ ++K +N +E EA +N V+ ++ +L+
Sbjct: 1339 RYFGEQPNDPNSKNLFFKRVDSFIIDYSKARSDNLKSEEEEASQHRRLNLVNNHKEHVLE 1398
Query: 1208 KASTETQVEKSADDEAADTIDILIKKLRSV 1237
+A +E D+EA +D + KLR+V
Sbjct: 1399 RAMSE---NNKMDNEA---MDGFLDKLRNV 1422
>SPAC20G4.02c [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1372
Score = 149 bits (375), Expect = 4e-35
Identities = 114/444 (25%), Positives = 204/444 (45%), Gaps = 20/444 (4%)
Query: 801 KPLKQIHWDKIE-DISDTLWNEPTTRSDLKE-DLNEKGVFNEIVNLFEQKAVRMKKKSNV 858
K LKQ+HW ++E TLWN L L +G+F ++ + + + V + K
Sbjct: 876 KRLKQLHWKRLEVPFEKTLWNIVVADPYLLTLKLTAEGIFKQLEDCYPLREVTVSNK--- 932
Query: 859 TASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSVLEFFNKDD 918
K E + DL Q I LH F+S + ++ K CD DI++ +++FFN
Sbjct: 933 ---KVKEYTGFMPVDLQQMVSIRLHRFNSLTPIEIAKKFFHCDHDIME---LVDFFNDRK 986
Query: 919 FETIPQSIIRSFEPYASDWKTGKAP-KEDVSKLERADRIYLEMFYNMRYYWKIRSSSLLI 977
F + + + +PY S E + +L R D+IY + ++ Y++ R ++L I
Sbjct: 987 FFR-QEGLKKQLKPYMSSRNEEVMEVSEKLLELSRFDQIYTLIVVDIDTYYEKRMAALKI 1045
Query: 978 ALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMNN--KKTQGIKLSSL 1035
++ D Q++K+ + +K+S K F +V+ IGNFMN+ ++ +G +L SL
Sbjct: 1046 KSFLANNFRDFRRQIRKLHCASLELKSSLHFKYFLNLVLHIGNFMNDAPRRAKGYRLESL 1105
Query: 1036 NKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXXXXXXXXXXXX 1095
+ SM+K N L+ LH IE+I+R +P + F DL + ++
Sbjct: 1106 LRASMIK-NDKTGLTLLHTIEKIVRTHFPQLEAFLVDLKAIPEISRFNLEQLEQDCNDIC 1164
Query: 1096 XXXMRMKESF-ERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLHNQCKLTMNDFNST 1154
+++ F G S+ + HPDD + + +PS + L++ +T
Sbjct: 1165 ERMKNVEKDFSNEGIFSNHKALHPDDHICEVMVPWIPSGKSMVDELNSDITELKTTLKTT 1224
Query: 1155 MKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREAMNRVHEQRQQLLQKASTETQ 1214
+ GE+P + FF N +E + + K S N++ E + R Q L+ +
Sbjct: 1225 LLMYGENPDEPTSSARFFNNLNEIILEYKKASTVNQKMEKEEELAFLRLQALKASVKSNN 1284
Query: 1215 VEKSA---DDEAADTIDILIKKLR 1235
E S ++E + T++ LI +L+
Sbjct: 1285 AENSGSSKNEEVSATMENLISQLQ 1308
>SPCC895.05 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1461
Score = 126 bits (316), Expect = 3e-28
Identities = 97/425 (22%), Positives = 190/425 (43%), Gaps = 16/425 (3%)
Query: 801 KPLKQIHWDKIEDISDTLWNEPTTRSDLKEDLNEKG-VFNEIVNLFEQKAVRMKKKSNVT 859
+PLK++HW +++ + T+ L D+ K + N +++ ++K ++ V
Sbjct: 853 RPLKRVHWQRVDPLPGP---NVFTKFCLNFDITAKVFIDNGLLDFLDEKFDNTPREDFVA 909
Query: 860 ASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSVLEFFNKDDF 919
+++ SLL + Q I L S+ VEDL+ K L + D + S+L F
Sbjct: 910 VEISDQRSSLLPDTVEQNMAIILRSVSNMPVEDLVQKFL-VEPDFLPA-SILYFDRASLA 967
Query: 920 ETIPQSIIRSFEPYASDW--KTGKAPKEDVSKLERADRIYLEMFYNMRYYWKIRSSSLLI 977
T + F PY++D+ K K P DV+ L ++ ++ N+R+Y++ R +L
Sbjct: 968 ST--NAYTDPFIPYSTDYTKKNPKEPTADVNSLSYFEKFFVLFVVNLRHYFQERMKALKF 1025
Query: 978 ALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMNNK--KTQGIKLSSL 1035
T D + +++++ D + I +FF +++ IGN+ N + L +
Sbjct: 1026 RSTLFGDLEILEVRMKEVIDTSDSIMEDKNFAEFFQVLLIIGNYFNEPYDRASAFSLYMI 1085
Query: 1036 NKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXXXXXXXXXXXX 1095
+L ++ +S L+ +H + IIR ++P++ ++ +
Sbjct: 1086 YRLETLRDSSSA-LTLMHYFDEIIRTRFPELLQAESTFKKIQSVSGYNIDAMVAGVDGAY 1144
Query: 1096 XXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLHNQCKLTMNDFNSTM 1155
+ S + G LS ++HHPDDK +S LP A + + + +T+
Sbjct: 1145 DEFCDFQTSLKDGALSKCDQHHPDDKAYDILSEWLPEAKERIRNIKKLKTDMLTKLENTV 1204
Query: 1156 KYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKER---EAMNRVHEQRQQLLQKASTE 1212
KY E + + +N+FF+N + F +++ EN+ER E + E R +L++
Sbjct: 1205 KYLCEYDSIDKVRNSFFKNLNSFYEMYSIAKAENEERFEKEKRRIMSEDRDKLIRGRQKT 1264
Query: 1213 TQVEK 1217
+ V K
Sbjct: 1265 SIVAK 1269
>Hs21071077 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1078
Score = 104 bits (260), Expect = 8e-22
Identities = 102/463 (22%), Positives = 202/463 (43%), Gaps = 42/463 (9%)
Query: 794 SKPKPEVKPLKQIHWDKIED--ISDTLWNEPTTRSDLKEDLNEKGVFNEIVNLFEQK--- 848
S P+P LK +W K+ + + T+W E +++ VF +I++L + +
Sbjct: 602 SIPQP-TNALKSFNWSKLPENKLEGTVWTE----------IDDTKVF-KILDLEDLERTF 649
Query: 849 -AVRMKKKSNVTASKKNEKVSLLSRDLAQQFGIN-LHMFSSYSVED--LLIKVLRCDDDI 904
A + ++ V ++ K ++ + L+ + + L + ++ +L+ L+ +D
Sbjct: 650 SAYQRQQDFFVNSNSKQKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDE 709
Query: 905 IKNHSVLEFFNKDDFETIPQSIIRS---FEPYASDWKTGKAPKEDVSKLERADRIYLEMF 961
IK D+ E +P+ ++ F P SD + K ++ ++ +ADR EM
Sbjct: 710 IKR----AILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLEEHKHELDRMAKADRFLFEMS 765
Query: 962 YNMRYYWKIRSSSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNF 1021
Y +++S L + + ++ +++ I G+ + S LKQ +V+ GN+
Sbjct: 766 RINHYQQRLQS--LYFKKKFAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGNY 823
Query: 1022 MNNKK---TQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSD 1078
MN + G K+SSLNK++ K++ DKN++ LH + I+ KYP + + +L +
Sbjct: 824 MNKGQRGNAYGFKISSLNKIADTKSSIDKNITLLHYLITIVENKYPSVLNLNEELRDIPQ 883
Query: 1079 LGXXXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAE 1138
++ E K ++ P DKF +S + A
Sbjct: 884 AAKVNMTELDKEISTLRSGLKAVETELEYQK---SQPPQPGDKFVSVVSQFITVASFSFS 940
Query: 1139 LLHNQCKLTMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQEN----KEREA 1194
+ + + F +K+ GE+ + + FF F +FL ++ QEN K++E
Sbjct: 941 DVEDLLAEAKDLFTKAVKHFGEEAGKIQ-PDEFFGIFDQFLQAVSEAKQENENMRKKKEE 999
Query: 1195 MNRVHEQRQQLLQKASTETQVEKSADD-EAADTIDILIKKLRS 1236
R QL ++ E ++ K+ ++ E + D L+ LRS
Sbjct: 1000 EERRARMEAQLKEQRERERKMRKAKENSEESGEFDDLVSALRS 1042
>Hs22060175 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 796
Score = 93.6 bits (231), Expect = 2e-18
Identities = 97/437 (22%), Positives = 189/437 (43%), Gaps = 34/437 (7%)
Query: 796 PKPEVKPLKQIHWDKI--EDISDTLWNEPTTRSDLKE-DLNEKGVFNEIVNLFEQKAVRM 852
P+P PLK +W K+ E + T+WNE + DL + F ++ + +++ +
Sbjct: 318 PQPS-HPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLED---FEKMFSAYQRHQELI 373
Query: 853 KKKSNVTASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSVLE 912
S E + L SR + + I+ + + LL K+ +++I ++L+
Sbjct: 374 TNPSQQKELGSTEDIYLASRKVKELSVIDGRRAQNCII--LLSKLKLSNEEI--RQAILK 429
Query: 913 FFNKDDFETIPQSIIRSFEPYASDWKTGKAPKEDVSKLERADRIYLEMFYNMRYYWKIRS 972
++D + F P SD + K ++ ++ RADR EM Y +++
Sbjct: 430 MDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQ- 488
Query: 973 SSLLIALTYEKDYYDILYQ----LQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMNNKK-- 1026
AL ++K + + L + ++ I + + S RL+Q +++ IGNFMN +
Sbjct: 489 -----ALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRG 543
Query: 1027 -TQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXX 1085
G +++SLNK++ K++ D+N+S LH + I+ + +PDI + +L L +
Sbjct: 544 GAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLA 603
Query: 1086 XXXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLHNQCK 1145
++ E + P DKF +S + + L +Q
Sbjct: 604 ELEKEVGNLRRGLRAVEVELE---YQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLN 660
Query: 1146 LTMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREAMNRVHEQRQQL 1205
+ F + + GE + + + FF F FL F S+ ++ EAM R E+ +
Sbjct: 661 EARDKFAKALMHFGEHDSKMQ-PDEFFGIFDTFLQAF---SEARQDLEAMRRRKEEEE-- 714
Query: 1206 LQKASTETQVEKSADDE 1222
++A E +++ + E
Sbjct: 715 -RRARMEAMLKEQRERE 730
>7298710 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous
Length = 1091
Score = 82.8 bits (203), Expect = 3e-15
Identities = 114/503 (22%), Positives = 205/503 (40%), Gaps = 62/503 (12%)
Query: 795 KPKPEVK-PLKQIHWDKI--EDISDTLWNEPTTRSDLKEDLNEKGVFNEIVNLFEQKAVR 851
K K +VK P+K+ +W I +SD + L +D E+ F K V+
Sbjct: 602 KKKWDVKNPMKRANWKAIVPAKMSDKAFWVKCQEDKLAQD----DFLAELAVKFSSKPVK 657
Query: 852 MKKKSNV----TASKKNEKVSLLSRDLAQQFGINLH-MFSSYSVEDLLIKVLRCDDDIIK 906
++K V T +KKN + +L AQ I L S E + I +LRCD DI+
Sbjct: 658 KEQKDAVDKPTTLTKKNVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILS 717
Query: 907 NHSVLEFFNKDDFETIPQSIIRSFEP--YASDWKTGKAPKEDVSKLERADRIYLEMFYNM 964
++ I Q +I+ P + + KA E + +E+ E+
Sbjct: 718 SN-------------ILQQLIQYLPPPEHLKRLQEIKAKGEPLPPIEQFAATIGEIK--- 761
Query: 965 RYYWKIRSSSLLIALTYEKDYYDILYQLQK-IDDGTSM---IKNSNRLKQFFYIVVEIGN 1020
R S L L ++ Y D++ ++ I GT+ I+NS + + +++ +GN
Sbjct: 762 ------RLSPRLHNLNFKLTYADMVQDIKPDIVAGTAACEEIRNSKKFSKILELILLLGN 815
Query: 1021 FMN----NKKTQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRL 1076
+MN N+ G ++S L KLS K ++D + LH + ++ +K+PD +F DL+ +
Sbjct: 816 YMNSGSKNEAAFGFEISYLTKLSNTK-DADNKQTLLHYLADLVEKKFPDALNFYDDLSHV 874
Query: 1077 SDLGXXXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRK 1136
+ ++ + K+ + DDKF ++ K R+
Sbjct: 875 NKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQCD----DDKF-SEVMGKFAEECRQ 929
Query: 1137 AELLHNQCKLTMND-FNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQEN----KE 1191
+ + +L M + +Y DP+ + FF + F F +N +E
Sbjct: 930 QVDVLGKMQLQMEKLYKDLSEYYAFDPSKYTMEE-FFADIKTFKDAFQAAHNDNVRVREE 988
Query: 1192 REAMNRVHEQRQQLLQKASTETQVEKS-ADDEAADTIDILIKKLRSVDPQQTIPGSSVPG 1250
E R+ E R+Q ++ Q +K+ D +A T + ++ L + + S G
Sbjct: 989 LEKKRRLQEAREQSAREQQERQQRKKAVVDMDAPQTQEGVMDSL-----LEALQTGSAFG 1043
Query: 1251 TSSHPEKRSTPRTNRDQNLLSRA 1273
+ +R P + LSR+
Sbjct: 1044 QRNRQARRQRPAGAERRAQLSRS 1066
>Hs5803003 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous
Length = 1101
Score = 82.0 bits (201), Expect = 5e-15
Identities = 108/491 (21%), Positives = 204/491 (40%), Gaps = 51/491 (10%)
Query: 797 KPEVKPLKQIHWDKIE--DISDT-LWNEPTTRSDLKEDLNEKGVFNEIVNLFEQK-AVRM 852
KPEV +K+I+W KIE ++S+ W DL K N + QK A +
Sbjct: 633 KPEVS-MKRINWSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNFATQIKVQKNAEAL 691
Query: 853 KKKSNVTASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSVLE 912
++K KK +++ +L AQ I L + ED+ +L ++D++
Sbjct: 692 EEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRM-PYEDIRNVILEVNEDMLS------ 744
Query: 913 FFNKDDFETIPQSIIRSF--EPYASDWKTGKAPKEDVSKLERADRIYLEMFYNMRYYWKI 970
E + Q++++ + ++ K +D+ + E+ + + +
Sbjct: 745 -------EALIQNLVKHLPEQKILNELAELKNEYDDLCEPEQFGVVMSSV-----KMLQP 792
Query: 971 RSSSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMN----NKK 1026
R SS+L LT+E+ +I + + +K S + +V+ +GN+MN N +
Sbjct: 793 RLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQ 852
Query: 1027 TQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXXX 1086
+ G K++ L K+ K ++D+ + LH I I EKY DI F +L +
Sbjct: 853 SLGFKINFLCKIRDTK-SADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQI 911
Query: 1087 XXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLHNQCKL 1146
+ ++ + K E H DKF +K+++ +A + E L
Sbjct: 912 LKSNLASMEQQIVHLERDIK--KFPQAENQH--DKFVEKMTSFTKTAREQYEKLSTMHNN 967
Query: 1147 TMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREAMNRVHEQRQQLL 1206
M + + +Y D + + + FF + + F TLF + +EN +R M + +
Sbjct: 968 MMKLYENLGEYFIFD-SKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAK 1026
Query: 1207 QKASTE---------TQVEKSADDEAADTIDILIKKLRS----VDPQQTIPGSSVPGTSS 1253
+KA E ++ + + + +D L++ L+S D ++ IP + P
Sbjct: 1027 EKAEQEKLERQKKKKQLIDINKEGDETGVMDNLLEALQSGAAFRDRRKRIPRN--PDNRR 1084
Query: 1254 HPEKRSTPRTN 1264
P +RS R N
Sbjct: 1085 VPLERSRSRHN 1095
>Hs6382071 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous
Length = 1096
Score = 81.6 bits (200), Expect = 7e-15
Identities = 108/491 (21%), Positives = 206/491 (40%), Gaps = 53/491 (10%)
Query: 797 KPEVKPLKQIHWDKIE--DISDT-LWNEPTTRSDLKEDLNEKGVFNEIVNLFEQK-AVRM 852
KPEV +K+I+W KIE ++S+ W DL K N + QK A +
Sbjct: 633 KPEVS-MKRINWSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNFATQIKVQKNAEAL 691
Query: 853 KKKSNVTASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSVLE 912
++K KK +++ +L AQ I L + ED+ +L ++D++
Sbjct: 692 EEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRM-PYEDIRNVILEVNEDMLS------ 744
Query: 913 FFNKDDFETIPQSIIRSF--EPYASDWKTGKAPKEDVSKLERADRIYLEMFYNMRYYWKI 970
E + Q++++ + ++ K +D+ + E+ + + +
Sbjct: 745 -------EALIQNLVKHLPEQKILNELAELKNEYDDLCEPEQFGVVMSSV-----KMLQP 792
Query: 971 RSSSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMN----NKK 1026
R SS+L LT+E+ +I + + +K S + +V+ +GN+MN N +
Sbjct: 793 RLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQ 852
Query: 1027 TQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXXX 1086
+ G K++ L K+ K ++D+ + LH I I EKY DI F +L +
Sbjct: 853 SLGFKINFLCKIRDTK-SADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQI 911
Query: 1087 XXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLHNQCKL 1146
+ ++ + K E H DKF +K+++ +A + E L
Sbjct: 912 LKSNLASMEQQIVHLERDIK--KFPQAENQH--DKFVEKMTSFTKTAREQYEKLSTMHNN 967
Query: 1147 TMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREAMNRVHEQRQQLL 1206
M + + +Y D + + + FF + + F TLF + +EN +R M + +
Sbjct: 968 MMKLYENLGEYFIFD-SKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAK 1026
Query: 1207 QKASTE---------TQVEKSADDEAADTIDILIKKLRS----VDPQQTIPGSSVPGTSS 1253
+KA E ++ + + + +D L++ L+S D ++ IP + V +
Sbjct: 1027 EKAEQEKLERQKKKKQLIDINKEGDETGVMDNLLEALQSGAAFRDRRKRIPRNPV---VN 1083
Query: 1254 HP-EKRSTPRT 1263
HP R+ PR+
Sbjct: 1084 HPCATRANPRS 1094
>Hs20535708 [TZ] KOG1923 Rac1 GTPase effector FRL
Length = 853
Score = 79.3 bits (194), Expect = 4e-14
Identities = 101/439 (23%), Positives = 184/439 (41%), Gaps = 53/439 (12%)
Query: 810 KIEDISDTLWNEPTTRSDLKEDLNEKGVFNEIVNLFEQKA----VRMKKKSNVTASKKNE 865
K I+ T++NE L EDLN +E +F+ KA + + K +
Sbjct: 396 KPNQINGTVFNEIDDERIL-EDLN----VDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSN 450
Query: 866 KVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSVLEFFNKDDFETIPQS 925
KV+LL + A+ I L K + D+I K V D +T+P
Sbjct: 451 KVTLLEANRAKNLAITLR------------KAGKTADEICKAIHVF------DLKTLPVD 492
Query: 926 IIRS---FEPYASDWKTGKAPKEDVSKLERA---DRIYLEMFYNMRYYWKIRSSSLLIAL 979
+ F P ++ K + + + LE DR ++ R K+ + +
Sbjct: 493 FVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLMQKMTIMAFIG-- 550
Query: 980 TYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMNNKK---TQGIKLSSLN 1036
+ + + QL I + IK+S +LK+ I++ +GN+MN+ K G KL SL+
Sbjct: 551 NFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLD 610
Query: 1037 KLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXXXXXXXXXXXXX 1096
L K ++D+ + LH I +++EKY + F +L+ +
Sbjct: 611 LLLDTK-STDRKQTLLHYISNVVKEKYHQVSLFYNELHYVE----------KAAAVSLEN 659
Query: 1097 XXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLHNQCKLTMNDFNSTMK 1156
+ +KE +RG + T++ + + + + K + L + K+ + F+ +K
Sbjct: 660 VLLDVKE-LQRG-MDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVK 717
Query: 1157 YCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREAMNRVHEQRQQLLQKASTETQVE 1216
Y GE+P + + FF F F+ + + +EN+ R+ + ++ L Q+A E Q
Sbjct: 718 YFGENP-KTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEK-LLEQEALMEQQDP 775
Query: 1217 KSADDEAADTIDILIKKLR 1235
KS ++ LI +LR
Sbjct: 776 KSPSHKSKRQQQELIAELR 794
>Hs20550654 [TZ] KOG1923 Rac1 GTPase effector FRL
Length = 347
Score = 77.0 bits (188), Expect = 2e-13
Identities = 59/222 (26%), Positives = 103/222 (45%), Gaps = 19/222 (8%)
Query: 991 QLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMNNKK---TQGIKLSSLNKLSMVKTNSDK 1047
QL I ++ +K+S +LKQ I++ +GN+MN+ K G KL SL+ L K ++D+
Sbjct: 65 QLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTK-STDR 123
Query: 1048 NLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXXXXXXXXXXXXXXXMRMKESFER 1107
++ LH I ++EKYPD+ +F +L+ + + +KE
Sbjct: 124 KMTLLHFIALTVKEKYPDLANFWHELHFVE----------KAAAVSLENVLLDVKELGRG 173
Query: 1108 GKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLHNQCKLTMNDFNSTMKYCGEDPTNSEA 1167
+L E D+ + L + K + L K +N+ ++Y GE P +
Sbjct: 174 MELIRRECSIHDNSVLRNF---LSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESP-KTTP 229
Query: 1168 KNTFFRNFSEFLTLFNKISQENKEREAMNRVHEQRQQLLQKA 1209
+ FF F F+ + + QEN+ R+ V ++ QL Q+A
Sbjct: 230 PSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREK-QLAQEA 270
>Hs5174401 [TZ] KOG1923 Rac1 GTPase effector FRL
Length = 463
Score = 73.2 bits (178), Expect = 3e-12
Identities = 69/256 (26%), Positives = 117/256 (44%), Gaps = 31/256 (12%)
Query: 947 VSKLERADRIYLEMFYNMRY---YWKI-RSSSLLIALTYEKDYYD----ILYQLQKIDDG 998
+++ ER R E+ R+ + +I R + LT+ ++ D ++ QL I
Sbjct: 124 ITRFEREQRPMEELSEEDRFMLCFSRIPRLPERMTTLTFLGNFPDTAQLLMPQLNAIIAA 183
Query: 999 TSMIKNSNRLKQFFYIVVEIGNFMNNKK---TQGIKLSSLNKLSMVKTNSDKNLSFLHVI 1055
+ IK+S++L+Q IV+ GN+MN+ K G +L SL+ L +K ++D+ + LH +
Sbjct: 184 SMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMK-STDRKQTLLHYL 242
Query: 1056 ERIIREKYPDIYDFTRDLNRLSDLGXXXXXXXXXXXXXXXXXXMRMKESFERG-KLSHTE 1114
++I EKYP + F DL+ L G S +RG +L+ E
Sbjct: 243 VKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLADV-----------RSLQRGLELTQRE 291
Query: 1115 KHHPDD--KFRKKISAKLPSAVRKAELLHNQCKLTMNDFNSTMKYCGEDPTNSEAKNTFF 1172
DD ++ + A P+ + L K F S ++Y GE+P + + FF
Sbjct: 292 FVRQDDCMVLKEFLRANSPT----MDKLLADSKTAQEAFESVVEYFGENP-KTTSPGLFF 346
Query: 1173 RNFSEFLTLFNKISQE 1188
FS F+ + K QE
Sbjct: 347 SLFSRFIKAYKKAEQE 362
>Hs13569895 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous
Length = 691
Score = 73.2 bits (178), Expect = 3e-12
Identities = 76/300 (25%), Positives = 129/300 (42%), Gaps = 39/300 (13%)
Query: 792 FVSKPKPEVKP---LKQIHWDKI---EDISDTLWNEPTTRSDLKEDLNEKGVFNEIVNLF 845
F KPK E KP +++++W KI E + W + DL K + N F
Sbjct: 369 FGLKPKKEFKPEISMRRLNWLKIRPHEMTENCFWIKVNENKYENVDLLCK-----LENTF 423
Query: 846 --EQKAVRMKK--KSNVTASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCD 901
+QK R ++ + + KK +++ L +AQ I L F E++ + +L D
Sbjct: 424 CCQQKERREEEDIEEKKSIKKKIKELKFLDSKIAQNLSIFLSSFR-VPYEEIRMMILEVD 482
Query: 902 DDIIKNHSVLEFFNKDDFETIP-QSIIRSFEPYASDWKTGKAPKEDVSKLERADRIYLEM 960
+ + + +P Q + S + S++ P++ V + R+
Sbjct: 483 ETRLAESMIQNLIKH-----LPDQEQLNSLSQFKSEYSNLCEPEQFVVVMSNVKRL---- 533
Query: 961 FYNMRYYWKIRSSSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGN 1020
+ R S++L L +E+ +I + + IK S + +V+ +GN
Sbjct: 534 --------RPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKSFSKLLELVLLMGN 585
Query: 1021 FMN----NKKTQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRL 1076
+MN N +T G LSSL KL K+ +D+ + LH + I EKYPDI +F DL L
Sbjct: 586 YMNAGSRNAQTFGFNLSSLCKLKDTKS-ADQKTTLLHFLVEICEEKYPDILNFVDDLEPL 644
>Hs4885183 [TZ] KOG1924 RhoA GTPase effector DIA/Diaphanous
Length = 1248
Score = 71.2 bits (173), Expect = 1e-11
Identities = 97/468 (20%), Positives = 198/468 (41%), Gaps = 64/468 (13%)
Query: 797 KPEVKPLKQIHWDKI--EDIS-DTLWNEPTTRSDLKEDLNEKG-VFNEIVNLFEQKAVRM 852
KPEV+ L++ +W K+ ED+S D W + +KED E +F ++ F +
Sbjct: 753 KPEVQ-LRRPNWSKLVAEDLSQDCFWTK------VKEDRFENNELFAKLTLTFSAQTKTK 805
Query: 853 K-----KKSNVTASKKNEKVSLLSRDLAQQFGINLHMFSS--YSVEDLLIKVLRCDDDII 905
K ++ KK +++ +L AQ I L F +++++++V
Sbjct: 806 KDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSFRMPYQEIKNVILEV-------- 857
Query: 906 KNHSVLEFFNKDDFETIPQSIIRSFEPYASDWKTGKAPKEDVSKLERADRIYLEMFYNMR 965
N +VL E++ Q++I+ P K K++ L +++ + M R
Sbjct: 858 -NEAVLT-------ESMIQNLIKQM-PEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPR 908
Query: 966 YYWKIRSSSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMN-- 1023
+ R +++L L + + +I ++ + ++ S I + +GN+MN
Sbjct: 909 L--RPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLLVGNYMNAG 966
Query: 1024 --NKKTQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGX 1081
N G +S L KL K+ +D+ ++ LH + + YPD+ F +L +
Sbjct: 967 SRNAGAFGFNISFLCKLRDTKS-TDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKASR 1025
Query: 1082 XXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLH 1141
++ + + EK DKF +K++ S V+ A+ +
Sbjct: 1026 VSAENLQKNLDQMKKQISDVERDVQNFPAATDEK----DKFVEKMT----SFVKDAQEQY 1077
Query: 1142 NQCKLTMNDFNSTMKYCGE----DPTNSEAKNTFFRNFSEFLTLFNKISQENKER----E 1193
N+ ++ ++ + K GE DP + FF + F +F + +EN++R E
Sbjct: 1078 NKLRMMHSNMETLYKELGEYFLFDPKKLSVEE-FFMDLHNFRNMFLQAVKENQKRRKTEE 1136
Query: 1194 AMNRV-----HEQRQQLLQKASTETQVEKSADDEAADTIDILIKKLRS 1236
M R ++++L ++ E ++ +A+ + +D L++ L+S
Sbjct: 1137 KMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQS 1184
>CE23783 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1034
Score = 71.2 bits (173), Expect = 1e-11
Identities = 73/305 (23%), Positives = 126/305 (40%), Gaps = 25/305 (8%)
Query: 950 LERADRIYLEMFYNMRYYWKIRSSSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLK 1009
L ADR E+ R+ ++R L I ++ ++ +Q + TS + + R +
Sbjct: 718 LALADRYMYEISSIPRFEQRLRC--LNIIRSFHDRVEALVPFIQVVLKATSSCQQNKRFR 775
Query: 1010 QFFYIVVEIGNFMN----NKKTQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPD 1065
Q I++ IGN++N N G +++S+NKL+ VK + + LH + I +KYPD
Sbjct: 776 QILTIILAIGNYLNFGKRNGNAYGFEMASINKLADVKNALRNDRNLLHFLVNFIEKKYPD 835
Query: 1066 IYDFTRDLNRLSDLGXXXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEK-----HHP-- 1118
+ F +D +++ + +++ E L T K H P
Sbjct: 836 LTKFKKDFATVTEAARFSQSETAAEIRNLEEALLIVRK--ELNLLESTTKVELPEHIPPE 893
Query: 1119 DDKFRKKISAKLPSAVRKAELLHNQCKLTMNDFNSTMKYCGEDPTNS-EAKNTFFRNFSE 1177
+D+F A + A + L + N F+ KY P+ FF ++
Sbjct: 894 NDRFALVAKAFIEKATAEYHNLDKMFREMKNKFSDCAKYFCYSPSGGVPVPEEFFSVINK 953
Query: 1178 FLTLFNKISQ----ENKEREAMNRVHEQRQQLLQKASTETQVEKSADDEAADTIDILIKK 1233
FL FN+ Q E +E E + R R L +K++T + D + LI
Sbjct: 954 FLNTFNEYHQQLWAEVEEEEKIKRQTIARSFLAKKSTTRRKENHKERD-----FEQLISA 1008
Query: 1234 LRSVD 1238
L+S D
Sbjct: 1009 LQSGD 1013
>7294416 [TZ] KOG1923 Rac1 GTPase effector FRL
Length = 1043
Score = 69.7 bits (169), Expect = 3e-11
Identities = 94/404 (23%), Positives = 169/404 (41%), Gaps = 57/404 (14%)
Query: 901 DDDIIKNHSV-LEFFNKDDFETIPQSIIRSFEPYASDWKTGKAPKEDVSKLERADRIYLE 959
DD I HS+ L+ + ++ E + + + E +K ++D L D+ L+
Sbjct: 662 DDVIAAIHSLDLKKLSLENVELLQKMVPTDAE--VKSYKEYIIERKDQQLLTEEDKFMLQ 719
Query: 960 MFYNMRYYWKIRSSSLLIALTYEKDYYDILY----QLQKIDDGTSMIKNSNRLKQFFYIV 1015
+ R SS L + Y ++ D ++ Q+Q I ++ +K S + K IV
Sbjct: 720 LSRVERI------SSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIV 773
Query: 1016 VEIGNFMNNKK---TQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRD 1072
+ GN++N+ K G KL SL+ L K ++DK S LH I IR K+P++ +F +
Sbjct: 774 LAFGNYLNSNKRGPAYGFKLQSLDTLIDTK-STDKRSSLLHYIVATIRAKFPELLNFESE 832
Query: 1073 L---NRLSDLGXXXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEK---HHPDDKFRKKI 1126
L ++ + + + E +G +H + ++ +DK +K
Sbjct: 833 LYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQTHILRDFLNNSEDKLKK-- 890
Query: 1127 SAKLPSAVRKAELLHNQCKLTMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKIS 1186
K++L H Q F ++Y G+ N++A FF F F +
Sbjct: 891 --------IKSDLRHAQ-----EAFKECVEYFGDSSRNADAA-AFFALIVRFTRAFKQHD 936
Query: 1187 QENKER------EAMNRVHEQRQQLL--QKASTETQVEKSADDEAADTIDILIKKLRSVD 1238
QEN++R A+ ++ Q+L K + + Q E ++ + + KKL D
Sbjct: 937 QENEQRLRLEKAAALAASKKENDQVLMRNKVNQKKQQEAVINELKSKAHSVREKKLLQQD 996
Query: 1239 PQQTIPGS---SVPGTSSHPEKRS-----TPRTNRDQNLLSRAM 1274
+ G+ + G S P +R+ + R D N LSR +
Sbjct: 997 --EVYNGALEDILLGLKSEPYRRADAVRRSQRRRIDNNRLSRTL 1038
>7290137 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1429
Score = 68.6 bits (166), Expect = 6e-11
Identities = 92/453 (20%), Positives = 186/453 (40%), Gaps = 60/453 (13%)
Query: 796 PKPEVKPLKQIHWDKIED--ISDTLWNEPTTRSDLKEDLNEKGVFNEIVNLFEQKAVRMK 853
P+P PLK +W K+ D + T+W+E L+E ++N + K
Sbjct: 900 PQP-TNPLKSFNWSKLPDAKLQGTVWSE----------LDESKLYNNMELESIDKLFSAY 948
Query: 854 KKSNVTASKKN-EKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSVLE 912
+K+ V+A+ + E + + + Q+ + + + LL K+ D +I K ++L
Sbjct: 949 QKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSKLKMSDMEISK--AILS 1006
Query: 913 FFNKDDFETIPQSIIRSFEPYASDWKTGKAPKEDVSKLERADRIYLEMFYNMRYYWKIRS 972
+ + + + F P A + ED+ L RADR E+ Y +++S
Sbjct: 1007 MDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRFLYEISKIPHYEQRLKS 1066
Query: 973 SSLLIALTYEKDYY----DILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIG--------- 1019
L Y+K + D++ ++ + + + + S RL++ +V+ +G
Sbjct: 1067 ------LHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGMIHCPFAKH 1120
Query: 1020 -----------NFMNNK---KTQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPD 1065
N+MN G +L+SLN+L+ K+++ K + LH + ++I K+ D
Sbjct: 1121 SITQTTSIPPGNYMNRGARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKD 1180
Query: 1066 IYDFTRDLNRLSDLGXXXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKK 1125
+ D+ + + + E + S + D+F
Sbjct: 1181 LLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQ--GDRFLPV 1238
Query: 1126 I-SAKLPSAVRKAELLHNQCKLTMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNK 1184
+ ++VR AE L ++ + F+ ++ GED + + + FF F FL F +
Sbjct: 1239 MREFHAQASVRFAE-LEDKFQDMKTRFDRAVRLFGEDGSVLQ-PDEFFGIFDSFLAAFAE 1296
Query: 1185 ISQENKEREAMNRVHEQRQQLLQKASTETQVEK 1217
+N E+ R E+ + ++A E +++K
Sbjct: 1297 ARHDN---ESFRRRQEEEE---KRAKQEAELKK 1323
>At5g07770 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 721
Score = 65.9 bits (159), Expect = 4e-10
Identities = 100/470 (21%), Positives = 181/470 (38%), Gaps = 59/470 (12%)
Query: 796 PKPEVKPLKQIHWDKI-EDISDTLWNEPTTRSDLKEDLNEKGVFNEIVNLFEQKAVRMKK 854
P + LK +HW KI + +LW+E + + E V EI LF A K
Sbjct: 185 PVTKRSSLKPLHWVKITRALQGSLWDELQIQYGESQTAIELDV-PEIETLFSVGAKPRPK 243
Query: 855 KSNVTASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSVLEFF 914
K EKV L+ A +NL + + D++ V+ D+ ++
Sbjct: 244 P-------KPEKVPLIDLKRANNTIVNLKILKM-PLPDMMAAVMAMDESVL--------- 286
Query: 915 NKDDFETIPQSIIRSFEPYASDWKTGKAPKEDVSKLERADRIYLEMFYNMRYYWKIRSSS 974
+ D E + Q P + + K D + L ++++ LE+ R+ K+R S
Sbjct: 287 DVDQIENLIQLC-----PTKEEMELLKNYTGDKATLGKSEQCLLELMKVPRFEAKLRVLS 341
Query: 975 LLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMNNKKTQG----I 1030
I + + + L ++ +++S LK+ I++ +GN +N +G
Sbjct: 342 FKIPFGTKITKFRKM--LNVVNSACEEVRSSQMLKEIMKIILFLGNTLNQGTARGSAVGF 399
Query: 1031 KLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXXXXXXX 1090
+L SL LS + +++K ++ +H + +++ K D+ DF +DL L
Sbjct: 400 RLDSLLILSETRADNNK-MTLMHYLCKVLASKAADLLDFHKDLQSLESTLEINLKSLAEE 458
Query: 1091 XXXXXXXXMRMKESFERGKLSHTEKHHP-DDKFRKKISAKLPSA---VRKAELLHNQCKL 1146
++K+ +L+ +E P FRK + + SA V L++ K
Sbjct: 459 IHAITKGLEKLKQ-----ELTASETDGPVSQVFRKLLKDFISSAETQVATVSTLYSSAKK 513
Query: 1147 TMNDFNSTMK-YCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREAMNRVHEQRQQL 1205
+ + K CG+ A F+ LF K QEN ++E + + + +
Sbjct: 514 VAHCYVVANKNTCGDRLPAVSA------TLLSFIRLFKKAHQENVKQEDLEKKKAATEDV 567
Query: 1206 LQKASTETQVEKSADDEAADTIDILIKKLRSVDPQQTIPGSSVPGTSSHP 1255
+ S DD A + P + P S+P S P
Sbjct: 568 FGGPDHNIDSDTSLDDSEAKS------------PSRIRPPPSIPRPPSRP 605
>CE27278 [TZ] KOG1923 Rac1 GTPase effector FRL
Length = 1088
Score = 62.4 bits (150), Expect = 4e-09
Identities = 54/222 (24%), Positives = 97/222 (43%), Gaps = 19/222 (8%)
Query: 1007 RLKQFFYIVVEI----GNFMNNKK---TQGIKLSSLNKLSMVKTNSDKNLSFLHVIERII 1059
R Q F+ V+E+ GN+MN+ K G KLSSL+ L+++K +D++L+ LH+I I
Sbjct: 795 REAQLFHGVLEVILAFGNYMNSGKRGGAYGFKLSSLDSLAILKAPADRSLTLLHMIVAEI 854
Query: 1060 REKYPDIYDFTRDLNRLSDLGXXXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEKHHPD 1119
+ P + F+ L + MKE K++ E+
Sbjct: 855 EKNLPHLKTFSEQLKFVD----------KATSVQWDSVQTDMKELAAGFKMAEKEQELKG 904
Query: 1120 DKFRKKISAKLPSAVRKAELLHNQCKLTMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFL 1179
+ +S S +K L +L + F ++ GE+ S + FF+ + F+
Sbjct: 905 TDCPEALSTFTASRKQKMADLEQAFQLAASSFKDCCEFYGEN-EKSTSPTVFFQKLAHFV 963
Query: 1180 TLFNKISQENKEREAM-NRVHEQRQQLLQKASTETQVEKSAD 1220
+ K EN+ + A+ R E+ ++ + AST++ D
Sbjct: 964 QNYQKCRGENEAKAALEKRRQEEAERRARVASTKSSASSEQD 1005
>Hs20533991 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1119
Score = 58.2 bits (139), Expect = 8e-08
Identities = 76/395 (19%), Positives = 151/395 (37%), Gaps = 47/395 (11%)
Query: 851 RMKKKSNVTASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSV 910
R + N + + E++++L + GI L F S+
Sbjct: 127 RRGRTLNSSFREAREEITILDAKRSMNIGIFLKQFKK------------------SPRSI 168
Query: 911 LEFFNKDDFETIPQSIIRSFE---PYASDWKTGKAPKEDVSKLERADRIYLEMFYNMRYY 967
+E ++ E +R F P + + K KA DVSKL AD + Y
Sbjct: 169 VEDIHQGKSEHYGSETLREFLKFLPESEEVKKLKAFSGDVSKLSLADSFLYGLIQVPNY- 227
Query: 968 WKIRSSSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMNNK-- 1025
+R ++++ + + + + + + L ++V++ GN MN
Sbjct: 228 -SLRIEAMVLKKEFLPSCSSLYTDITVLRTAIKELMSCEELHSILHLVLQAGNIMNAGGY 286
Query: 1026 --KTQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXX 1083
G KLSSL KL+ K N ++ LH + + ++K + +F+ L+ +
Sbjct: 287 AGNAVGFKLSSLLKLADTKANKP-GMNLLHFVAQEAQKKDTILLNFSEKLHHVQKTARLS 345
Query: 1084 XXXXXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLHNQ 1143
+KE+ +R D + +++ L A+ K L
Sbjct: 346 LENTEAELHLLFVRTKSLKENIQR-----------DGELCQQMEDFLQFAIEKLRELECW 394
Query: 1144 CKLTMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREA-----MNRV 1198
+ ++ + + + ED + F + F +F T FNK ++N +REA + R+
Sbjct: 395 KQELQDEAYTLIDFFCEDKKTMKLDECF-QIFRDFCTKFNKAVKDNHDREAQELRQLQRL 453
Query: 1199 HEQRQQLLQKASTETQVEKSADDEAADTIDILIKK 1233
EQ Q+ Q++ ++ + + +++L KK
Sbjct: 454 KEQEQK--QRSWATGELGAFGRSSSENDVELLTKK 486
>At5g07780 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 464
Score = 55.8 bits (133), Expect = 4e-07
Identities = 85/431 (19%), Positives = 164/431 (37%), Gaps = 42/431 (9%)
Query: 794 SKPKPEVKPLKQIHW-DKIEDISDTLWNEPTTRSDLKEDLNEKGVFNEIVNLFEQKAVRM 852
S+P LK +HW K + +LW+E R + + D+ ++ + I +
Sbjct: 69 SRPPKTKCSLKPLHWVKKTRALPGSLWDELQRRQECR-DIEDEQILCAIELSVSEIETIF 127
Query: 853 KKKSNVTASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDIIKNHSVLE 912
+ + EKV L+ A I L M + + D++ + D+ +
Sbjct: 128 SLGAKPKPKPEPEKVPLIDLRRATNTEIRL-MLLNIRLPDMIAAAMAMDESRL------- 179
Query: 913 FFNKDDFETIPQSIIRSFEPYASDWKTGKAPKEDVSKLERADRIYLEMFYNMRYYWKIRS 972
DDF+ I +++I F P D K D E+ + E+ R K+R
Sbjct: 180 ----DDFDQI-ENLINLF-PTKEDMKFLLTYTGDKGNCEQLFQYLQEVVKVPRVESKLRV 233
Query: 973 SSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMNNK----KTQ 1028
S I + + L ++ I+ S +LK ++ +GN +N +
Sbjct: 234 FSFKIQ--FGTQITKLTKGLNAVNSACEEIRTSQKLKDIMENILCLGNILNQGTGRGRAV 291
Query: 1029 GIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXXXXX 1088
G +L SL LS + ++ K ++ +H + +++ K D+ DF +DL L
Sbjct: 292 GFRLDSLLILSETRADNSK-MTLMHYLCKVLASKASDLLDFHKDLESLESASKIQLKSLA 350
Query: 1089 XXXXXXXXXXMRMKESFERGKLSHTEKHHP-DDKFRKKISAKLPSAVRKAELLHNQCKLT 1147
++K+ +L+ +E P FRK + + +A + +
Sbjct: 351 EEIQAITKGLEKLKQ-----ELTASETDGPVSQVFRKLLKEFISNAETQVATVMALYYPA 405
Query: 1148 MNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREAMNRVHEQRQQLLQ 1207
+ + Y G + T F+ LF K +EN ++ + + +
Sbjct: 406 RGNAEALAHYFGYHYPFEQVTATLL----SFIRLFKKAHEENVKQAELEK---------K 452
Query: 1208 KASTETQVEKS 1218
KA+ E ++EK+
Sbjct: 453 KAAKEAEMEKT 463
>7295293 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 1034
Score = 55.5 bits (132), Expect = 5e-07
Identities = 89/445 (20%), Positives = 173/445 (38%), Gaps = 50/445 (11%)
Query: 796 PKPEVKPLKQIHWDKIEDIS----DTLWNEPTTRSDLKEDLNEKGVFNEIVNLF------ 845
P P+ K +K I+W KI +W+ S+ ++ + +NE+ LF
Sbjct: 329 PAPKAK-MKTINWGKIPHNKVLGKQNIWS--IVASNHQDSPMQDIDWNEMEGLFCLQTAS 385
Query: 846 EQKAVRMKKKSNVTASKKNEKVSLLSRDLAQQFGINLHMFSSYSVEDLLIKVLRCDDDII 905
Q + ++ + + A+ N +L + + I L ++ +K R +D
Sbjct: 386 AQGSPKLGRDGSQAAAGSNGCDTLDRKSKKESTEITLLDGKRSLNVNIFLKQFRTSND-- 443
Query: 906 KNHSVLEFFNKDDFETIPQSIIRSF---EPYASDWKTGKAPKEDVSKLERADRIYLEMFY 962
+++ + E I +R P + K D ++L A++ L++
Sbjct: 444 ---DIIQLIRQGAHEEIGAERLRGLLKIMPEVDELDMLKGFNGDKARLGNAEKFLLQLLE 500
Query: 963 NMRYYWKIRSSSLLIALTYEKDYYD--ILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGN 1020
Y +I S L Y + I L DD + N+ L++ Y+VV GN
Sbjct: 501 VPNYKLRIESMLLKEEFAANVAYLEPCINSMLYAGDD----LLNNKTLQEVLYMVVVAGN 556
Query: 1021 FMNN----KKTQGIKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRL 1076
F+N+ G+KLSSL KL+ ++ N ++ +H + ++ P++ FT L+ L
Sbjct: 557 FLNSGGYAGNAAGVKLSSLQKLTDIRANK-PGMNLIHFVALQAEKRNPELLQFTGQLSNL 615
Query: 1077 SDLGXXXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEKHHPDDKFRKKIS--AKLPSAV 1134
R+ E+ K D + S + L + +
Sbjct: 616 ESASKTTSEQINNEINTLDGRIRRIARQIEQPATDVDIKEQMADFLQAAESELSVLQAGM 675
Query: 1135 RKAELLHNQCKLTMNDFNSTMKYCGEDPTNSEAKNTFFRNFSEFLTLFNKISQENKEREA 1194
++ E + +L M++F +C D + F+ F F F + +EN+ R+
Sbjct: 676 KQVESM----RLKMSEF-----FC--DDAATFRLEECFKIFHNFCDKFKQAVKENERRQ- 723
Query: 1195 MNRVHEQRQQLLQKASTETQVEKSA 1219
+++Q L++ E Q+ + A
Sbjct: 724 ----QQEQQATLRRKQREEQLARRA 744
>At5g07760 [TZ] KOG1922 Rho GTPase effector BNI1 and related formins
Length = 832
Score = 54.3 bits (129), Expect = 1e-06
Identities = 58/278 (20%), Positives = 117/278 (41%), Gaps = 27/278 (9%)
Query: 892 DLLIKVLRCDDDIIKNHSVLEFFNKDDFETIPQSIIRSFEPYASDWKTGKAPKEDVSKLE 951
D++ VL D+ ++ D + I +++IR F P + K K D + L
Sbjct: 524 DMMAAVLGMDESVL------------DVDQI-ENLIR-FCPTKEEMKLLKNYTGDKATLG 569
Query: 952 RADRIYLEMFYNMRYYWKIRSSSLLIALTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQF 1011
+ ++ +LE+ K+R S I + ++ L ++ I+ S +LK+
Sbjct: 570 KCEQYFLELMKVPGVESKLRVFSFKIH--FGTQIKELNKGLNTVNSACEEIRTSQKLKEI 627
Query: 1012 FYIVVEIGNFMNNKKTQG----IKLSSLNKLSMVKTNSDKNLSFLHVIERIIREKYPDIY 1067
I++ +GN +N +G KL SL LS K +++ N++ +H + +++ K D+
Sbjct: 628 MKIILCLGNILNQGTARGSAVGFKLDSLLNLSE-KCSANTNMTLMHYLCKVLASKASDLL 686
Query: 1068 DFTRDLNRLSDLGXXXXXXXXXXXXXXXXXXMRMKESFERGKLSHTEKHHP-DDKFRKKI 1126
DF +DL L ++ + +L+ +E P + FRK +
Sbjct: 687 DFHKDLENLESASKIHLKSLAEEMVAITKGLQKLNQ-----ELTASESDGPISEVFRKLL 741
Query: 1127 SAKLPSAVRKAELLHNQCKLTMNDFNSTMKYCGEDPTN 1164
+ A + + + + ++ + Y GEDP +
Sbjct: 742 KDFISVAETQVATVSSLYSSVGGNTDALVHYFGEDPND 779
>Hs13399326 [TZ] KOG1925 Rac1 GTPase effector FHOS
Length = 418
Score = 53.5 bits (127), Expect = 2e-06
Identities = 49/237 (20%), Positives = 93/237 (38%), Gaps = 8/237 (3%)
Query: 979 LTYEKDYYDILYQLQKIDDGTSMIKNSNRLKQFFYIVVEIGNFMNNKKTQGIKLSSLNKL 1038
+ YE ++ L + +G ++N+ L ++ IGNF+N + +LS L K+
Sbjct: 50 MDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTNAKAFELSYLEKV 109
Query: 1039 SMVKTNSDKNLSFLHVIERIIREKYPDIYDFTRDLNRLSDLGXXXXXXXXXXXXXXXXXX 1098
VK K S LH + ++ E +PD D ++ ++
Sbjct: 110 PEVKDTVHKQ-SLLHHVCTMVVENFPDSSDLYSEIGAIT---RSAKVDFDQLQDNLCQME 165
Query: 1099 MRMKESFERGKLSHTEKHHPDDKFRKKISAKLPSAVRKAELLHNQCKLTMNDFNSTMKYC 1158
R K S++ L KH ++++S L + +L + +N F+S + +
Sbjct: 166 RRCKASWDH--LKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRIINRFHSFLLFM 223
Query: 1159 GEDP--TNSEAKNTFFRNFSEFLTLFNKISQENKEREAMNRVHEQRQQLLQKASTET 1213
G P N F R SEF + + +++ H +R + K T++
Sbjct: 224 GHPPYAIREVNINKFCRIISEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITDS 280
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.132 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,208,801
Number of Sequences: 60738
Number of extensions: 2739496
Number of successful extensions: 10122
Number of sequences better than 1.0e-05: 25
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 10035
Number of HSP's gapped (non-prelim): 47
length of query: 1283
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1165
effective length of database: 23,222,132
effective search space: 27053783780
effective search space used: 27053783780
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)