ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2881 check: MH L KOG0220 Replication, recombination and repair Mismatch repair ATPase MSH4 (MutS family)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2881 1018880 1016217 -888
(888 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFL003c [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 684 0.0
Hs20535615 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 309 1e-83
Hs4505251 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 308 3e-83
CE24714 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 229 1e-59
CE21000 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 170 1e-41
YCR092c [L] KOG0218 Mismatch repair MSH3 169 2e-41
At4g17380 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 153 1e-36
Hs4557761 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 149 2e-35
YDR097c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 142 3e-33
SPAC8F11.03 [L] KOG0218 Mismatch repair MSH3 135 3e-31
Hs4505249 [L] KOG0218 Mismatch repair MSH3 134 5e-31
At4g02070 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 132 3e-30
YOL090w [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 125 3e-28
SPBC24C6.12c [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 120 1e-26
Hs21361940 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 115 3e-25
Hs4505253 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 115 4e-25
7298155 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 113 1e-24
SPCC285.16c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 108 4e-23
ECU03g0540 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 108 5e-23
Hs4504191 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 105 3e-22
ECU10g0710 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 100 1e-20
At4g25540 [L] KOG0218 Mismatch repair MSH3 98 6e-20
CE28985 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 97 1e-19
YDL154w [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 85 4e-16
At3g20475 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 83 2e-15
CE26678 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 82 3e-15
At3g24320 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 64 8e-10
At3g18525 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 60 1e-08
CE04858 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 59 3e-08
>YFL003c [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 878
Score = 684 bits (1766), Expect = 0.0
Identities = 376/872 (43%), Positives = 558/872 (63%), Gaps = 39/872 (4%)
Query: 39 SQNNSRVSRHSTSKKRKVDRQPT-------------IFELSNHQQERDCSLP---IRKSM 82
+ +++ +S+ ST K + + PT I E + E+D + + SM
Sbjct: 21 ANSSNSISKPSTKKSIRNQKSPTNISSWALKKKTLQIAETTWENNEKDSTHSHYLMTGSM 80
Query: 83 QTRQSKSESRYTSRNKKITTTTSGLVVGP--DRTIFSIFESGKNADTRVGICVVNYSTAE 140
+R + S SRY+ T+ ++GP D + I+E ++ TR+G+C++N +T +
Sbjct: 81 ASRTATSLSRYS---------TNASLLGPSIDCVLCCIYEVPRDISTRIGLCIINCNTGQ 131
Query: 141 MHVSEFIDTQVFIKTLNKIYVCQPTEILIPSHSLSGKVSKLSTIVKCNISDNVKICEAAT 200
M++S+F+D+Q++I+ ++K+ + QPTEILIPS SL+ VSKL+T++K N+++ VKI E +
Sbjct: 132 MYLSDFMDSQIYIRVVHKLQIYQPTEILIPSSSLAPTVSKLATMIKFNVAETVKIEEGSR 191
Query: 201 KVYNPQEGLEVLEKFALLGTNKSPVPFAEQLIGKEFCLMAVSAASNYMTQI-AEADLALK 259
K +N Q+GL + K+ + T K E++I K F L A SAA +YM +I +++ L
Sbjct: 192 KCFNSQDGLAAITKYLMDDTKKDLK--IEEIIDKTFALCAASAAISYMEEIISKSSRNLN 249
Query: 260 -FSNFRVRIDNGDNTMLIDMKTVQSLELIENTLESNGMTLLKVIDKTVTKMGHRALRNDI 318
F R++ + +NTMLID KTV+ LEL+EN L+ NG++L K +D T TKMG R+LRN I
Sbjct: 250 AFRKLRIQFEGTENTMLIDSKTVRGLELVENKLDKNGISLWKFLDTTSTKMGQRSLRNSI 309
Query: 319 LQPLTDINSLKLRVSAVQELQNNPDFLNSFRMELKVLHDLDALFSKLLSFNHTVILPDQK 378
LQPLTD S+++R+ A++EL+ N D L R+E+K L DLD LFS+LL NH+ I PDQ+
Sbjct: 310 LQPLTDRGSIEMRLEALEELKANDDLLQKLRLEMKSLPDLDKLFSRLLCINHSAIKPDQR 369
Query: 379 LNYVILLKESIESATTLKRXXXXXXXXXXXXXXIMAXXXXXXXXXXXXLINRYLNEDTRW 438
+NYV+LLKE+++S +LK LIN +NED W
Sbjct: 370 INYVLLLKETLQSVKSLKDALNDQLIQSRLISETKKIFNNDAIMEIEKLINSCINEDCVW 429
Query: 439 ASTPIDLQNQKAYAIKRGSNGLLDVLRQLYKSLTDDIMREVDSLRDKFGLNFSHGHDVNR 498
AS+ I L NQ++YA+K SNGLLDV RQ+YK + ++ REV+ L K +N H +D R
Sbjct: 430 ASSAIQLLNQRSYAVKSDSNGLLDVSRQIYKEVKEEFFREVEDLTAKNKINLDHNYDSAR 489
Query: 499 QFYLKLKKKDI-NQLSDLDSCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALSEQT 557
FYL++K+++ + ++ L FI+R KK E TTLN++K N RL E+ E++ LSE+T
Sbjct: 490 GFYLRIKRQEFTDDVATLPDVFISRTIKKNYIECTTLNIIKKNARLKEVMEEILLLSEET 549
Query: 558 VSELLSNISSHIATLFMISEAISVLDLLCSLATTGLENNWILASFGNHLSLSGARHPILE 617
V ELL I++HI+ LFMI+EA+++LDL+CS ENN+ + F N+L + +RHP+LE
Sbjct: 550 VDELLDKIATHISELFMIAEAVAILDLVCSFTYNLKENNYTIPIFTNNLLIRDSRHPLLE 609
Query: 618 NTLTNFVANDVEAIPNLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPL 677
L NFV N + + + SS QI+TGCNMSGKS+YLKQVA++ I+AQ+G +P SFP+
Sbjct: 610 KVLKNFVPNTISSTKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPALYGSFPV 669
Query: 678 YQKLHARVCNDDIEAYSSTFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALA 737
+++LHARVCND +E SS F EMK+MAYF+DDI +TL+ILDELGRGSSIADGF ++LA
Sbjct: 670 FKRLHARVCNDSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIADGFCVSLA 729
Query: 738 ISEYLLSKNATVFLSTHFRDIPKILAPKPRVLHLEMKTEIDQESHLKMKYKASTESEEIE 797
++E+LL ATVFLSTHF+DIPKI++ KP V HL M + ++ +KM Y+ + +S IE
Sbjct: 730 VTEHLLRTEATVFLSTHFQDIPKIMSKKPAVSHLHMDAVLLNDNSVKMNYQLTQKSVAIE 789
Query: 798 GYGMMICKRIFSERIMLEAYKISELLRASKRKGLKIIAKEDSCDNACQTT--QIKQVYYL 855
G+ + K+IF+ I+ EAY I LL+ +K + EDS Q T Q+K+++ L
Sbjct: 790 NSGIRVVKKIFNPDIIAEAYNIHSLLKIAKAR----TENEDSNGVVDQKTINQMKRIHNL 845
Query: 856 VQKLKAFCNHEK-TIDIEELRSLQDDFISTFE 886
V LK +EK + + +L+ + DFI FE
Sbjct: 846 VAILKECAGNEKEPLTLGKLKEINSDFIENFE 877
>Hs20535615 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 936
Score = 309 bits (791), Expect = 1e-83
Identities = 215/711 (30%), Positives = 354/711 (49%), Gaps = 20/711 (2%)
Query: 102 TTTSGLVVGPDRTIFSIFESGKNADTRVGICVVNYSTAEMHVSEFIDTQVFIKTLNKIYV 161
+++S + I ++ E A +G+ ++ ++ +S+F D + K + K+ +
Sbjct: 144 SSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKNPQIILSQFADNTTYAKVITKLKI 203
Query: 162 CQPTEILIPSHSLS-GKVSKLSTIVKCNISDNVKICEAATKVYNPQEGLEVLEKFALLGT 220
P EI++ + + + G +KL T++ N NV K +N +GLE +E+ +
Sbjct: 204 LSPLEIIMSNTACAVGNSTKLFTLITENFK-NVNFTTIQRKYFNETKGLEYIEQLCI--A 260
Query: 221 NKSPVPFAEQLIGKEFCLMAVSAASNYMTQIAEADLALKFSNFRVRIDNGDNTMLIDMKT 280
S V Q K +CL AV+A Y+ I + A K + ++ + T +ID +
Sbjct: 261 EFSTVLMEVQ--SKYYCLAAVAALLKYVEFIQNSVYAPK--SLKICFQGSEQTAMIDSSS 316
Query: 281 VQSLELIENTLE-SNGMTLLKVIDKTVTKMGHRALRNDILQPLTDINSLKLRVSAVQELQ 339
Q+LEL+ N + N TL V++ T T G R LR++IL+PL DI ++ +R+ VQEL
Sbjct: 317 AQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELL 376
Query: 340 NNPDFLNSFRMELKVLHDLDALFSKLLSF--NHTVILPDQKLNYVILLKESIESATTLKR 397
+ + + + D + L S L+ TV + K+ +I LK ++E LK
Sbjct: 377 QDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLK- 435
Query: 398 XXXXXXXXXXXXXXIMAXXXXXXXXXXXXLINRYLNEDTRWASTPIDLQNQKAYAIKRGS 457
I +N+D R+ ++++ QK YA++
Sbjct: 436 -IAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNI 494
Query: 458 NGLLDVLRQLYKSLTDDIMREVDSLRDKFGLNFSHGHDVNRQFYLKLKKKDINQLSD-LD 516
N LD+ R+ Y + DDI + L +K+ L R F++++ I SD L
Sbjct: 495 NEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLP 554
Query: 517 SCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALSEQTVSELLSNISSHIATLFMIS 576
S FI K +Y FT+ +L+KMN R E E+ ++ V +LLS I HI L+ +S
Sbjct: 555 SEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLS 614
Query: 577 EAISVLDLLCSLATTGLENNWILASFGNHLSLSGARHPILENTLTNFVANDVEAIPNLSS 636
+ +S+LD+L S A ++++ F + L++ HPILE + + S+
Sbjct: 615 DTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPIANNTYVTEGSN 674
Query: 637 FQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARVC-NDDIEAYSS 695
F I+TG NMSGKS YLKQ+A+ I+AQIG VP +SF + +++ R+ +DDIE SS
Sbjct: 675 FLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSS 734
Query: 696 TFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSKNATVFLSTHF 755
TF EMK++AY + + DK+L+++DELGRG++ +G I A+ EYLLS A +THF
Sbjct: 735 TFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLSLKAFTLFATHF 794
Query: 756 RDIPKILAPKPRV--LHLE---MKTEIDQESHLKMKYKASTESEEIEGYGM 801
++ I A P V +H E +K + + YK S E + YG+
Sbjct: 795 LELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGL 845
>Hs4505251 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 936
Score = 308 bits (788), Expect = 3e-83
Identities = 215/711 (30%), Positives = 354/711 (49%), Gaps = 20/711 (2%)
Query: 102 TTTSGLVVGPDRTIFSIFESGKNADTRVGICVVNYSTAEMHVSEFIDTQVFIKTLNKIYV 161
+++S + I ++ E A +G+ ++ ++ +S+F D + K + K+ +
Sbjct: 144 SSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKNPQIILSQFADNTTYAKVITKLKI 203
Query: 162 CQPTEILIPSHSLS-GKVSKLSTIVKCNISDNVKICEAATKVYNPQEGLEVLEKFALLGT 220
P EI++ + + + G +KL T++ N NV K +N +GLE +E+ +
Sbjct: 204 LSPLEIIMSNTACAVGNSTKLFTLITENFK-NVNFTTIQRKYFNETKGLEYIEQLCI--A 260
Query: 221 NKSPVPFAEQLIGKEFCLMAVSAASNYMTQIAEADLALKFSNFRVRIDNGDNTMLIDMKT 280
S V Q K +CL AV+A Y+ I + A K + ++ + T +ID +
Sbjct: 261 EFSTVLMEVQ--SKYYCLAAVAALLKYVEFIQNSVYAPK--SLKICFQGSEQTAMIDSSS 316
Query: 281 VQSLELIENTLE-SNGMTLLKVIDKTVTKMGHRALRNDILQPLTDINSLKLRVSAVQELQ 339
Q+LEL+ N + N TL V++ T T G R LR++IL+PL DI ++ +R+ VQEL
Sbjct: 317 AQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELL 376
Query: 340 NNPDFLNSFRMELKVLHDLDALFSKLLSF--NHTVILPDQKLNYVILLKESIESATTLKR 397
+ + + + D + L S L+ TV + K+ +I LK ++E LK
Sbjct: 377 QDEELFFGLQSVISRFLDTEQLLSVLVQIPEQDTVNAAESKITNLIYLKHTLELVDPLK- 435
Query: 398 XXXXXXXXXXXXXXIMAXXXXXXXXXXXXLINRYLNEDTRWASTPIDLQNQKAYAIKRGS 457
I +N+D R+ ++++ QK YA++
Sbjct: 436 -IAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNI 494
Query: 458 NGLLDVLRQLYKSLTDDIMREVDSLRDKFGLNFSHGHDVNRQFYLKLKKKDINQLSD-LD 516
N LD+ R+ Y + DDI + L +K+ L R F++++ I SD L
Sbjct: 495 NEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSLSSVRGFFIQMTTDCIALPSDQLP 554
Query: 517 SCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALSEQTVSELLSNISSHIATLFMIS 576
S FI K +Y FT+ +L+KMN R E E+ ++ V +LLS I HI L+ +S
Sbjct: 555 SEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLS 614
Query: 577 EAISVLDLLCSLATTGLENNWILASFGNHLSLSGARHPILENTLTNFVANDVEAIPNLSS 636
+ +S+LD+L S A ++++ F + L++ HPILE + + S+
Sbjct: 615 DTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPIANNTYVTEGSN 674
Query: 637 FQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARVC-NDDIEAYSS 695
F I+TG NMSGKS YLKQ+A+ I+AQIG VP +SF + +++ R+ +DDIE SS
Sbjct: 675 FLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSS 734
Query: 696 TFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSKNATVFLSTHF 755
TF EMK++AY + + DK+L+++DELGRG++ +G I A+ EYLLS A +THF
Sbjct: 735 TFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLSLKAFTLFATHF 794
Query: 756 RDIPKILAPKPRV--LHLE---MKTEIDQESHLKMKYKASTESEEIEGYGM 801
++ I A P V +H E +K + + YK S E + YG+
Sbjct: 795 LELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGL 845
>CE24714 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 842
Score = 229 bits (585), Expect = 1e-59
Identities = 194/781 (24%), Positives = 353/781 (44%), Gaps = 51/781 (6%)
Query: 79 RKSMQTRQSKSESRYTSRNKKIT-----------TTTSGLVVGPDRTIFSIFESGKNADT 127
R+ Q +S+SE +++ ++ TTT V D + + E + +
Sbjct: 10 RQRQQVAESRSEEKFSRSLVRLNAQSLLDSSGNNTTTKN--VNSD-VVIVVMEGRGSCEG 66
Query: 128 RVGICVVNYSTAEMHVSEFIDTQVFIKTLNKIYVCQPTEILIPSHSLSGKVSKLSTIVKC 187
+GI + + E+H+ EF+D++ + I V + +I+I + + +KL
Sbjct: 67 HIGIALHDTCFPEIHLCEFVDSREYTTLKTMINVHEAFDIVIQNGNEERGSTKLLGEALM 126
Query: 188 NISDNVKICEAATKVYNPQEGLEVLEKFALLGTNKSPVPFAEQLIGKEFCLMAVSAASNY 247
+ ++K +N + G L+ +L+ S V +E + + L A++ Y
Sbjct: 127 TAFPEASLQSISSKYFNSERGERQLQ--SLMNAEVSTV--SEGCLRRTLALGALAVLLKY 182
Query: 248 MTQIAEADLALKFSNFRVRIDNGDNTMLIDMKTVQSLELIENTLESNGM--------TLL 299
+ + +K + R++ ++T +ID + +SLE+++ S TL+
Sbjct: 183 IHETRCVFFRVK--SLRIKEMGVNDTCMIDFVSWESLEIVDADDASKARKFQMKQKRTLM 240
Query: 300 KVIDKTVTKMGHRALRNDILQPLTDINSLKLRVSAVQELQNNPDFLNSFRMELKVLHDLD 359
V++ TVT G+R LR+ +LQP TD+ ++ R A++EL P + R L H+LD
Sbjct: 241 SVLNHTVTTNGYRLLRSSVLQPSTDVYLIQSRQEAIEELIGKPQLKDKLRRTLSRAHELD 300
Query: 360 ALFSKLL--SFNHTVILPDQKLNYVILLKES---IESATTLKRXXXXXXXXXXXXXXIMA 414
+ + + S + TV + K+N +I L + I+ TL +
Sbjct: 301 RVIAMCIQTSTSWTVRESEAKINQIIKLMHTLKVIQGIRTLLHSAKMKSNILIEKTEFLK 360
Query: 415 XXXXXXXXXXXXLINRYLNEDTRWASTPIDLQNQKAYAIKRGSNGLLDVLRQLYKSLTDD 474
L+ + + + LQN K YAI+ LD+ RQ Y ++
Sbjct: 361 DPRFDQIMNI--LVEKVDDSLLDGKKNSLHLQNTKCYAIRHFVAVQLDLARQTY----EE 414
Query: 475 IMREVDSLRDKFGLNFSHGHDV-------NRQFYLKLKKKDINQLSDLDSCFINRVTKKT 527
I+R V+ + + HG+ +R F+ + ++ + F++ +T
Sbjct: 415 IIRNVEETGAREIAEYFHGNSSVRLSFSQSRGFHYTFVTRQAESVT-IPRYFLDVFRNRT 473
Query: 528 AYEFTTLNLMKMNTRLSELTCEMIALSEQTVSELLSNISSHIATLFMISEAISVLDLLCS 587
F + ++ N RL ++ EM S+ V +++ + I L+ +A+S +D LC
Sbjct: 474 TVTFNSRKVIAYNDRLEQVVAEMFLASDVIVCDMIEEMQPMIPVLYYAMDALSSIDFLCG 533
Query: 588 LATTGLENNWILASFGNHLSLSGARHPILE-NTLTNFVANDVEAIPNLSSFQIVTGCNMS 646
LAT + +FG S+S RHPIL+ + + ND + F I+TG NM+
Sbjct: 534 LATYSDLRDTCKPTFGPSFSISQGRHPILDWDDSEKTITNDT-CLTRDRRFGIITGPNMA 592
Query: 647 GKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARV-CNDDIEAYSSTFSAEMKDMA 705
GKS YLKQ A L I+AQIGC +P AS P++ ++ +R+ ND++ S F++EM D A
Sbjct: 593 GKSTYLKQTAQLAIMAQIGCFIPANYASLPIFNRIFSRMGHNDELIRNKSAFASEMSDAA 652
Query: 706 YFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSKNATVFLSTHFRDIPKILAPK 765
+ +L++LDEL R +S +G +I AI E +L + FL+THF DI +
Sbjct: 653 AIVQYADKNSLVVLDELARSTSTEEGIAITYAICEKVLKLQSYTFLATHFLDIAALANYS 712
Query: 766 PRVLHLEMKTEIDQESHLKMKYKASTESEEIEGYGMMICKRIFSERIMLEAYKISELLRA 825
+ + + D+ S K K + G+ ++ I + ++ A ++ LRA
Sbjct: 713 NAIDNYHFLPQTDENSTKKHKLLRGQYRGPLYGFELVELSTI-PDEVIEHAQSLATELRA 771
Query: 826 S 826
+
Sbjct: 772 N 772
>CE21000 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 849
Score = 170 bits (430), Expect = 1e-41
Identities = 192/759 (25%), Positives = 329/759 (43%), Gaps = 96/759 (12%)
Query: 109 VGPDRTIFSIFESGKNADTRVGICVVNYSTAEMHVSEFIDTQVFIKTLNKIYVCQPTE-I 167
V I +I+ + D RV +C + + +SE+IDT F +T I+ PTE I
Sbjct: 123 VSDQAPILAIYIHPGDDDNRVTLCAWDAGNVRIVISEYIDTPSFSQTEQCIFGLCPTEYI 182
Query: 168 LIPSHSLSGKVSKLSTIVKCNISDNVKICEAATKVYNPQE------GLEVLEKFALLGTN 221
L+ S++ K K++++ +V+N Q+ +V+E L
Sbjct: 183 LVNEGSVAPKAKKIASMF------------TRMEVHNKQQLKPKSQWSDVIESVHL--DY 228
Query: 222 KSPVPFAEQLIGKEFCLMAVSAASNYMTQIAEADLALKFSNFRVRIDNGDNTMLIDMKTV 281
K + I + ++ +AA Y ++ K+S F MLID V
Sbjct: 229 KDEAEKQNENIKECLQILHSNAADEY-------SISEKYSIFNY---GTHGNMLIDSCAV 278
Query: 282 QSLELIE---NTLE-SNGMTLLKVIDKTVTKMGHRALRNDILQPLTDINSLKLRVSAVQE 337
++LEL + N LE SN +TL V++K T G + LR+ + +PL I+ + R+ V+
Sbjct: 279 EALELFQLNYNYLEKSNNLTLYNVLNKCKTLPGEKLLRDWLSRPLCQIDHINERLDIVEA 338
Query: 338 LQNNPDFLNSFRMELKV-LHDLDALFSKLLS---------FNHTVILPDQKLNYVILLKE 387
L N R + + D L +L+ F L + +I L E
Sbjct: 339 LFENQTIRQKLRDSILARMPDCSQLARRLMRKCTLQDLNRFYQAATLLETVEMQLIQLSE 398
Query: 388 SIESATTLKRXXXXXXXXXXXXXXIMAXXXXXXXXXXXXLINRYLNEDTRW---ASTPID 444
+ + A ++ R I L + R+ D
Sbjct: 399 AEQFAPSINRLLKSE-------------------------ITEILKKVERFQVLCDEFFD 433
Query: 445 LQNQKAYAIKRGSNGLLDVLRQLYKSLTDDIMREVDSLRDKFGLNFSHGH---DVNRQ-- 499
+K R + ++++ + L + + R + LR K+ F + D N Q
Sbjct: 434 FDYEKENKEIRVRVDFVPEIQEISEKL-EQMERVAEKLRKKYSAKFECDNLKLDKNSQYG 492
Query: 500 FYLKLKKKDINQLSDLDSCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALSEQTVS 559
FY ++ K+ + D I TK + +F+ L +N E + E+ +S
Sbjct: 493 FYFRVTLKEEKSIRKKD-VHILETTKGSGVKFSVGELSDINDEFLEFHLKYTRAEEEVIS 551
Query: 560 ELLSNISSHIATLFMISEAISVLDLLCSLATTGLENNWI------LASFGNHLSLSGARH 613
L I + +++ I+ LD+ SL+T ++ I L L L RH
Sbjct: 552 MLCKKAEEFIPLIPAMAQLIATLDVFVSLSTFAATSSGIYTRPNLLPLGSKRLELKQCRH 611
Query: 614 PILE-NTLTNFVANDVEAIPNLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTS 672
P++E N+ F+ NDV + + I+TG NM GKS YL+ A+ +LAQIG VPC+S
Sbjct: 612 PVIEGNSEKPFIPNDV--VLDKCRLIILTGANMGGKSTYLRSAALSILLAQIGSFVPCSS 669
Query: 673 ASFPLYQKLHARVCNDDIEAYS-STFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADG 731
A+ + + RV D ++ STF AEM D + + T + +++DELGRG+S DG
Sbjct: 670 ATISVVDGIFTRVGASDKQSQGISTFMAEMLDCSAILQRATKNSFVVIDELGRGTSTFDG 729
Query: 732 FSIALAISEYLLSK-NATVFLSTHFRDIPKILAPKPRVLHLEMKTEIDQESHLKMKYKAS 790
F IA AI++ +L++ +THF ++ K LA +P + L+M +I + + + M YK
Sbjct: 730 FGIASAIAQDILNRIQCLSIFATHFHEMGK-LAEQPGAVALQMGVQI-ENNEIHMLYKV- 786
Query: 791 TESEEIEGYGMMICKRIFSERIMLEAYKISELLRASKRK 829
E +G+ + K + + ++ K ++LL ++K
Sbjct: 787 FEGVAQCSFGLQVAKMVGIDENVIN--KAAQLLEGLEKK 823
>YCR092c [L] KOG0218 Mismatch repair MSH3
Length = 1047
Score = 169 bits (428), Expect = 2e-41
Identities = 186/752 (24%), Positives = 320/752 (41%), Gaps = 78/752 (10%)
Query: 108 VVGPDRTIFSI---FESGKNADTRVGICVVNYSTAEMHVSEFIDTQVFIKTLN-KIYVCQ 163
++G +I+++ GK A + + VN + E+ EF + + + L +I Q
Sbjct: 300 ILGDTNSIWALSRDVHQGKVA--KYSLISVNLNNGEVVYDEFEEPNLADEKLQIRIKYLQ 357
Query: 164 PTEILIPSHSLSGKVSKLSTIVKCNISDNVKICEAATKVYNPQEGLE--VLEKFALLGTN 221
P E+L+ + L V+K + C + ++ + LE V++ ++
Sbjct: 358 PIEVLVNTDDLPLHVAKFFKDISCPL------------IHKQEYDLEDHVVQAIKVMNEK 405
Query: 222 KSPVPFAEQLIGKEFCLMAVSAASNYMTQIAEADLALKFSNFRVRIDNGDNTMLIDMKTV 281
P +L+ K + M M + +S F +I ML+D ++
Sbjct: 406 IQLSPSLIRLVSKLYSHMVEYNNEQVML------IPSIYSPFASKIH-----MLLDPNSL 454
Query: 282 QSLELIENTLESNGMTLLKVIDKTVTKMGHRALRNDILQPLTDINSLKLRVSAVQELQ-- 339
QSL++ T + +L ++D T T G R LR IL+PL D++ ++ R+ A++ +
Sbjct: 455 QSLDIF--THDGGKGSLFWLLDHTRTSFGLRMLREWILKPLVDVHQIEERLDAIECITSE 512
Query: 340 -NNPDFLNSFRMELKVLHDLDALFSKLLSFNHTVILPDQKLNYVILLKESIESATTLKRX 398
NN F S L DL L + N + + LK+ K
Sbjct: 513 INNSIFFESLNQMLNHTPDL------LRTLNRIMYGTTSRKEVYFYLKQITSFVDHFKMH 566
Query: 399 XXXXXXXXXXXXXIMAXXXXXXXXXXXXLINRYLNEDTRWASTP-----IDLQNQKAYAI 453
+ L+ R +E ST + + N A
Sbjct: 567 QSYLSEHFKSSDGRIGKQSP--------LLFRLFSELNELLSTTQLPHFLTMINVSAVME 618
Query: 454 KRGSNGLLDVLRQLYKSLTDDIM---REVDSLRDKFGLNFSHGHDVNRQFYLKLKKK--- 507
K ++D ++ I+ RE +S+R + + ++ YL + +
Sbjct: 619 KNSDKQVMDFFNLNNYDCSEGIIKIQRESESVRSQLKEELAEIRKYLKRPYLNFRDEVDY 678
Query: 508 ----DINQLSDLDSCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALSEQTVSELLS 563
+Q+ DL +I K FTT K+ +L +I SE E L+
Sbjct: 679 LIEVKNSQIKDLPDDWIKVNNTKMVSRFTTPRTQKLTQKLEYYKDLLIRESELQYKEFLN 738
Query: 564 NISSHIATLFMISEAISVLDLLCSLATTGLENNWILASFGNH---LSLSGARHPILENTL 620
I++ L I+ ++ D + SLA T N++ +F N + AR+PI+E+
Sbjct: 739 KITAEYTELRKITLNLAQYDCILSLAATSCNVNYVRPTFVNGQQAIIAKNARNPIIESLD 798
Query: 621 TNFVANDVEAIPNLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQK 680
++V ND+ P I+TG NM GKS Y++QVA+LTI+AQIG VP +++
Sbjct: 799 VHYVPNDIMMSPENGKINIITGPNMGGKSSYIRQVALLTIMAQIGSFVPAEEIRLSIFEN 858
Query: 681 LHARV-CNDDIEAYSSTFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAIS 739
+ R+ +DDI STF EM D+ + + + ++L++LDE+GRG+ DG +I+ A+
Sbjct: 859 VLTRIGAHDDIINGDSTFKVEMLDILHILKNCNKRSLLLLDEVGRGTGTHDGIAISYALI 918
Query: 740 EYL--LSKNATVFLSTHFRDIPKILAPKPRVLHL----EMKTEIDQESHLKMKYKASTES 793
+Y LS + +THF + +I +P R H+ E KT D S + + YK +
Sbjct: 919 KYFSELSDCPLILFTTHFPMLGEIKSPLIRNYHMDYVEEQKTGEDWMSVIFL-YKLK-KG 976
Query: 794 EEIEGYGMMICKRI-FSERIMLEAYKISELLR 824
YGM + K + I+ A+ ISE LR
Sbjct: 977 LTYNSYGMNVAKLARLDKDIINRAFSISEELR 1008
>At4g17380 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 574
Score = 153 bits (386), Expect = 1e-36
Identities = 108/382 (28%), Positives = 192/382 (49%), Gaps = 33/382 (8%)
Query: 428 INRYLNEDTRWASTPIDLQNQKAYAIKRGSNGLLDVLRQLYKSLTDDIMREVDSLRDKFG 487
I +++D A P + Q+ +A+K G +G LD+ R+ + T I R++F
Sbjct: 190 IGEVIDDDVLHARVPFVARTQQCFALKAGIDGFLDIARRTFCDTT--IHNLASKYREEFN 247
Query: 488 L-NFSHGHDVNRQFYLKLKKKDINQLSDLDSCFINRVTKKTAYEFTTLNLMKMNTRLSEL 546
L N + + F+ ++ +K++ K +FT LN+ R
Sbjct: 248 LPNLKLPFNNRQGFFFRIPQKEVQG--------------KLPNKFTQLNV-----RNKSA 288
Query: 547 TCEMIALSEQTVSELLSNISSHIATLFMISEAISVLDLLCSLATTGLENNWI-------L 599
E +E + L+ I I+ L +++E + +LD++ + + + L
Sbjct: 289 AGECFIRTETCLEALMDAIREDISALTLLAEVLCLLDMIVNSFAHTISTKPVDRYSRPEL 348
Query: 600 ASFGNHLSLSGARHPILENTLTNFVANDVEAIPNLSSFQIVTGCNMSGKSIYLKQVAMLT 659
G L++ RHPILE+ +FV+N + + ++ +V G NMSGKS YL+QV ++
Sbjct: 349 TDSGP-LAIDAGRHPILESIHNDFVSNSI-FMSEATNMLVVMGPNMSGKSTYLQQVCLVV 406
Query: 660 ILAQIGCPVPCTSASFPLYQKLHARVCN-DDIEAYSSTFSAEMKDMAYFIDDITDKTLMI 718
ILAQIGC VP A+ + ++ R+ D++E+ SSTF EM++ A+ + ++T+++L++
Sbjct: 407 ILAQIGCYVPARFATIRVVDRIFTRMGTMDNLESNSSTFMTEMRETAFIMQNVTNRSLIV 466
Query: 719 LDELGRGSSIADGFSIALAISEYLLSKNATVFLSTHFRDIPKILAPKPRVLHLEMKTEID 778
+DELGR +S +DG ++A + EYLLS A +TH + ++ P V L +I
Sbjct: 467 MDELGRATSSSDGLAMAWSCCEYLLSLKAYTVFATHMDSLAELATIYPNVKVLHFYVDI- 525
Query: 779 QESHLKMKYKASTESEEIEGYG 800
+++ L K + S E E G
Sbjct: 526 RDNRLDFKVLSVFLSYEFETLG 547
>Hs4557761 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 934
Score = 149 bits (376), Expect = 2e-35
Identities = 165/732 (22%), Positives = 308/732 (41%), Gaps = 52/732 (7%)
Query: 121 SGKNADTRVGICVVNYSTAEMHVSEFIDTQVFIKTLNKIYVCQPTEILIPSHSLSGKVSK 180
S + +VG+ V+ ++ + EF D F + P E ++P +G + K
Sbjct: 153 SAVDGQRQVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAGDMGK 212
Query: 181 LSTIVKCN---ISDNVKICEAATKVYNPQEGLEVLEKFALLGTNKSPVPFAEQLIGKEFC 237
L I++ I++ K + +Y L +K + N + +P E +
Sbjct: 213 LRQIIQRGGILITERKKADFSTKDIYQDLNRLLKGKKGEQM--NSAVLPEMENQVA---- 266
Query: 238 LMAVSAASNYMTQIAEADLALKFSNFRVRIDNGDNTMLIDMKTVQSLELIENTLE--SNG 295
+ ++SA ++ +++ F F + + M +D+ V++L L + ++E +
Sbjct: 267 VSSLSAVIKFLELLSDDS---NFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGS 323
Query: 296 MTLLKVIDKTVTKMGHRALRNDILQPLTDINSLKLRVSAVQELQNNPDFLNSFRMEL-KV 354
+L +++K T G R + I QPL D N ++ R++ V+ + + + + +L +
Sbjct: 324 QSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRR 383
Query: 355 LHDLDALFSKLLSFNHTVILPDQKLNYVILLKESIESATTLKRXXXXXXXXXXXXXXIMA 414
DL+ L K L D Y + L ++
Sbjct: 384 FPDLNRLAKKFQ--RQAANLQDCYRLY--------QGINQLPNVIQALEKHEGKHQKLLL 433
Query: 415 XXXXXXXXXXXXLINRYLNEDTRWASTPIDLQNQKAYAIKRGSNGLLDVLRQLYKSLTDD 474
+++ ++ + +D + +K + L LR++ L
Sbjct: 434 AVFVTPLTDLRSDFSKF--QEMIETTLDMDQVENHEFLVKPSFDPNLSELREIMNDLEKK 491
Query: 475 IMREVDSLRDKFGLNFSHGH--DVNRQF--YLKLKKKDINQLSDLDSCFINRVTKKTAYE 530
+ + S GL+ D + QF Y ++ K+ L + + F +K +
Sbjct: 492 MQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRN-NKNFSTVDIQKNGVK 550
Query: 531 FTTLNLMKMNTRLSELTCEMIALSEQTVSELLSNISSHIATLFMISEAISVLDLLCSLA- 589
FT L +N ++ E + V E+++ S ++ + +++ ++ LD + S A
Sbjct: 551 FTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAH 610
Query: 590 -TTGLENNW----ILASFGNHLSLSGARHPILE-NTLTNFVANDVEAIPNLSSFQIVTGC 643
+ G + IL + L +RH +E F+ NDV + F I+TG
Sbjct: 611 VSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGP 670
Query: 644 NMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARVCNDDIEAYS-STFSAEMK 702
NM GKS Y++Q ++ ++AQIGC VPC SA + + ARV D + STF AEM
Sbjct: 671 NMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEML 730
Query: 703 DMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSK-NATVFLSTHFRDIPKI 761
+ A + T +L+I+DELGRG+S DGF +A AISEY+ +K A +THF ++ +
Sbjct: 731 ETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTAL 790
Query: 762 LAPKPRVLHLEMKTEIDQESHLKMKYKASTESEEIEGYGMMICKRIFSERIMLEAYKISE 821
P V +L + T + E L M Y+ +C + F + A
Sbjct: 791 ANQIPTVNNLHV-TALTTEETLTMLYQVKKG----------VCDQSFGIHVAELANFPKH 839
Query: 822 LLRASKRKGLKI 833
++ +K+K L++
Sbjct: 840 VIECAKQKALEL 851
>YDR097c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1242
Score = 142 bits (357), Expect = 3e-33
Identities = 150/703 (21%), Positives = 292/703 (41%), Gaps = 54/703 (7%)
Query: 130 GICVVNYSTAEMHVSEFIDTQVFIKTLNKIYVCQPTEILIPSHSLSGKVSKLSTIVKCNI 189
G ++ +T E+ + EF D K + +P E+++ ++LS +K IVK N
Sbjct: 468 GAAFIDTATGELQMLEFEDDSECTKLDTLMSQVRPMEVVMERNNLSTLANK---IVKFNS 524
Query: 190 SDNVKICE--AATKVYNPQEGLEVLEKFALLGTNKSPVPFAEQLI--GKEFCLMAVSAAS 245
+ N E A + Y+ + + T + + GK+ A
Sbjct: 525 APNAIFNEVKAGEEFYDCDKTYAEIISSEYFSTEEDWPEVLKSYYDTGKKVGFSAFGGLL 584
Query: 246 NYMTQIAEADLALKFSNFR-VRIDNGDNTMLIDMKTVQSLELIENTLE-SNGMTLLKVID 303
Y+ + + N + ++M++D T+Q+LE+ N+ + S+ TL K+ +
Sbjct: 585 YYLKWLKLDKNLISMKNIKEYDFVKSQHSMVLDGITLQNLEIFSNSFDGSDKGTLFKLFN 644
Query: 304 KTVTKMGHRALRNDILQPLTDINSLKLRVSAVQELQNNPDFLNSFRMELKVLHDLDALFS 363
+ +T MG R ++ ++ PL N ++ R+ +V L + + L DL+ + +
Sbjct: 645 RAITPMGKRMMKKWLMHPLLRKNDIESRLDSVDSLLQDITLREQLEITFSKLPDLERMLA 704
Query: 364 KLLSFNHTVILPDQKLNYVILLKESIESATTLKRXXXXXXXXXXXXXXIMAXXXXXXXXX 423
++ S T+ + D + + + IE +LK ++
Sbjct: 705 RIHS--RTIKVKDFE-KVITAFETIIELQDSLKNNDLKGD---------VSKYISSFPEG 752
Query: 424 XXXLINRYLNEDTRWASTPIDLQNQKAYAIKRGSNGLLDVLRQLYKSLTDDIMREVDSLR 483
+ + N R + N+ +RG + D + L D++M + + R
Sbjct: 753 LVEAVKSWTNAFERQKAI-----NENIIVPQRGFDIEFDKSMDRIQELEDELMEILMTYR 807
Query: 484 DKFGLNFSHGHDVNRQFYLKLKKKDINQLSDLDSCFINRVTKKTAYEFTTLNLMKMNTRL 543
+F + D ++ Y + I+ ++ S ++ KT + + + + +
Sbjct: 808 KQFKCSNIQYKDSGKEIYTI--EIPISATKNVPSNWVQMAANKTYKRYYSDEVRALARSM 865
Query: 544 SELTCEMIALSEQTVSELLSNISSHIATLFMIS-EAISVLDLLCSLATTG---------- 592
+E L E + L +H T++M + +AIS +D L ++ T
Sbjct: 866 AEAKEIHKTLEEDLKNRLCQKFDAHYNTIWMPTIQAISNIDCLLAITRTSEYLGAPSCRP 925
Query: 593 -------LENNWILASFGNHLSLSGARHPILE---NTLTNFVANDVEAIPNLSSFQIVTG 642
+ N L F L RHP T +F+ ND+E ++TG
Sbjct: 926 TIVDEVDSKTNTQLNGF---LKFKSLRHPCFNLGATTAKDFIPNDIELGKEQPRLGLLTG 982
Query: 643 CNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARV-CNDDIEAYSSTFSAEM 701
N +GKS L+ + I+AQ+GC VPC SA ++ R+ ND+I STF E+
Sbjct: 983 ANAAGKSTILRMACIAVIMAQMGCYVPCESAVLTPIDRIMTRLGANDNIMQGKSTFFVEL 1042
Query: 702 KDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSKNATV-FLSTHFRDIPK 760
+ +D T+++L+++DELGRG S +DGF+IA ++ ++ + ++ F +TH+ +
Sbjct: 1043 AETKKILDMATNRSLLVVDELGRGGSSSDGFAIAESVLHHVATHIQSLGFFATHYGTLAS 1102
Query: 761 ILAPKPRVLHLEMKTEIDQESHLKMKYKASTESEEIEGYGMMI 803
P+V L+M +D+ + E + +GM +
Sbjct: 1103 SFKHHPQVRPLKMSILVDEATRNVTFLYKMLEGQSEGSFGMHV 1145
>SPAC8F11.03 [L] KOG0218 Mismatch repair MSH3
Length = 1004
Score = 135 bits (340), Expect = 3e-31
Identities = 156/669 (23%), Positives = 290/669 (43%), Gaps = 67/669 (10%)
Query: 123 KNADTRVGICVVNYSTAEMHVSEFIDTQVFIKTLNKIYVCQPTEILIPSHSLSGKVSKLS 182
K+ +VG+ + S+ F D + + ++ QP E++ S K+S S
Sbjct: 248 KSGRVQVGLIAIQLSSGTTVYDHFQDDFLRSELQTRLSHFQPCELIY-----SNKLSSES 302
Query: 183 TIVKCNISDNVKICEAATKVYNPQE-----GLEVLEKFALLGTNKSPVPFAEQLIGK--- 234
+ + K C +V + + LE L+ F S E + K
Sbjct: 303 VALLNHYVSTEKTCGRVVRVQHAVQQDVKLALENLQDFFSSKCIMSGSKIIELHMEKVKS 362
Query: 235 --EFCLMAVSAASNYMTQIAEADLALKFSNFRVRIDNGDNTMLIDMKTVQSLELIENTLE 292
++ + A +Y+ + + DL + SNF D+ ++M++ + ++ LEL N +
Sbjct: 363 LHSLSIICLDMAISYLMEFSLEDLFVA-SNFYQPFDS-ISSMVLSKQALEGLELFVNQTD 420
Query: 293 SNGM-TLLKVIDKTVTKMGHRALRNDILQPLTDINSLKLRVSAVQELQ-NNPDFLNSFRM 350
+ +L V+D+T T+ G R L+ + +PL D ++ R+ AV+EL N+ + + R
Sbjct: 421 HTPVGSLFWVLDRTYTRFGQRMLQRWLQKPLVDKENIIERLDAVEELAFNSNSQVQAIRK 480
Query: 351 ELKVLHDLDALFSKLLSFNHTVILPDQKLNYVILLKESIESATTLKRXXXXXXXXXXXXX 410
L L DL+ S++ T P + + +LK ++A+ +
Sbjct: 481 MLYRLPDLEKGLSRIYYQRCT---PSEMFH---VLKGFYKAASAFSKNSYSCFKSALLRR 534
Query: 411 XIMAXXXXXXXXXXXXLINRYLN-------------------EDTRWASTPIDLQNQKAY 451
I +I+ +L ++ + P D+ + A
Sbjct: 535 LIQQLPSISS------IIDHFLGMFDQKEAENNNKVDMFKDIDNFDLSEEPNDVDYELAQ 588
Query: 452 AIKRGSNGLLDVLRQLYKSLTDDIMREVDSLRDKFGLNFSHGHDVNRQFYLKLKKKDINQ 511
I+ +L V ++ D ++E+ + L FS +V +F +++ K
Sbjct: 589 EIRELKMSILMVRTEM-----DFHLQELRDYLEYPNLEFSIWGNV--KFCIEVSKG---- 637
Query: 512 LSDLDSCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALSEQTVSELLSNISSHIAT 571
+ +I + ++ + F T + + LS + SE+ LS IS H
Sbjct: 638 CKKIPPDWIKLSSTRSLFRFHTPKIQSLLIELSSHEENLTISSEKIYRSFLSRISEHYNE 697
Query: 572 LFMISEAISVLDLLCSLATTGLENNWILASFGN-HLSLSGARHPILENTLT-NFVANDVE 629
L ++ + LD L S A ++ + F + L + +RHP++E +FV N +
Sbjct: 698 LRNVTTVLGTLDCLISFARISSQSGYTRPEFSDKELLIHESRHPMIELLSDKSFVPNHIH 757
Query: 630 AIPNLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARV-CND 688
+ ++TG NM GKS ++KQ+A+ I+AQ GC VP SA P++ + R+ +D
Sbjct: 758 LSSDGVRCLLITGPNMGGKSSFVKQLALSAIMAQSGCFVPAKSALLPIFDSILIRMGSSD 817
Query: 689 DIEAYSSTFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYL--LSKN 746
++ STF EM + + T+K+++I+DELGRG+S DG +I+ A+ YL K+
Sbjct: 818 NLSVNMSTFMVEMLETKEVLSKATEKSMVIIDELGRGTSTIDGEAISYAVLHYLNQYIKS 877
Query: 747 ATVFLSTHF 755
+F+ THF
Sbjct: 878 YLLFV-THF 885
>Hs4505249 [L] KOG0218 Mismatch repair MSH3
Length = 1128
Score = 134 bits (338), Expect = 5e-31
Identities = 175/770 (22%), Positives = 315/770 (40%), Gaps = 84/770 (10%)
Query: 123 KNADTRVGICVVNYSTAEMHVSEFIDTQVFIKTLNKIYVCQPTEILIPSHSLSGKVSKLS 182
K + +GI V +T E+ F D+ + ++ QP E+L+PS + +
Sbjct: 373 KKGNIFIGIVGVQPATGEVVFDSFQDSASRSELETRMSSLQPVELLLPSALSEQTEALIH 432
Query: 183 TIVKCNISDNVKICEAATKVYNPQEGL--EVLEKFALLGTNKSPVPFAEQLIGKEF-CLM 239
++ D+ E +Y V E +A + ++ E +
Sbjct: 433 RATSVSVQDDRIRVERMDNIYFEYSHAFQAVTEFYAKDTVDIKGSQIISGIVNLEKPVIC 492
Query: 240 AVSAASNYMTQIAEADLALKFSNFRVRIDNGDNTMLIDMKTVQSLELIENTLESNGM-TL 298
+++A Y+ + + K NF+ ++ + M I+ T+++LE+++N + +L
Sbjct: 493 SLAAIIKYLKEFNLEKMLSKPENFK-QLSSKMEFMTINGTTLRNLEILQNQTDMKTKGSL 551
Query: 299 LKVIDKTVTKMGHRALRNDILQPLTDINSLKLRVSAVQELQNNPDFLNSFRMELKVLHDL 358
L V+D T T G R L+ + QPL + + R+ AV E VLH
Sbjct: 552 LWVLDHTKTSFGRRKLKKWVTQPLLKLREINARLDAVSE----------------VLHSE 595
Query: 359 DALFSKLLSFNHTVILPDQKLNYVILLKESIESATTLKRXXXXXXXXXXXXXXIMAXXXX 418
++F ++ NH LPD + + + + I A
Sbjct: 596 SSVFGQIE--NHLRKLPDIERGLCSIYHKKCSTQEFFLIVKTLYHLKSEFQAIIPAVNSH 653
Query: 419 XXXXXXXXLINRYLNEDTRWASTPIDLQNQKAYAIKRGSNGLLDVLR-QLYKSLTDDIMR 477
+I + E + + N++A + + D+ L K D+I
Sbjct: 654 IQSDLLRTVILE-IPELLSPVEHYLKILNEQAAKVGDKTELFKDLSDFPLIKKRKDEIQG 712
Query: 478 EVDSLR------DKFGLNFSHGHDV--NRQFYLKLKKKDINQLSDLDSCFINRVTKKTAY 529
+D +R K N S + ++F +++K + S + + ++ + K
Sbjct: 713 VIDEIRMHLQEIRKILKNPSAQYVTVSGQEFMIEIKNSAV---SCIPTDWVKVGSTKAVS 769
Query: 530 EFTTLNLMKMNTRLSELTCEMIALSEQTVSELLSNISSHIATLFMISEAISVLDLLCSLA 589
F + +++ L++L +++ + L S H +L ++ +D + SLA
Sbjct: 770 RFHSPFIVENYRHLNQLREQLVLDCSAEWLDFLEKFSEHYHSLCKAVHHLATVDCIFSLA 829
Query: 590 TTGLENNWILASFGNH--LSLSGARHPILENTL---TNFVANDVEAIPNLSSFQIVTGCN 644
+ ++ + + + RHP+++ L +V N+ + + I+TG N
Sbjct: 830 KVAKQGDYCRPTVQEERKIVIKNGRHPVIDVLLGEQDQYVPNNTDLSEDSERVMIITGPN 889
Query: 645 MSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARV-CNDDIEAYSSTFSAEMKD 703
M GKS Y+KQVA++TI+AQIG VP A+ + + R+ D+I STF E+ D
Sbjct: 890 MGGKSSYIKQVALITIMAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGRSTFMEELTD 949
Query: 704 MAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLS--KNATVFLSTHFRDIPKI 761
A I T ++L+ILDELGRG+S DG +IA A EY + K+ T+F+ TH+
Sbjct: 950 TAEIIRKATSQSLVILDELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFV-THY------ 1002
Query: 762 LAPKPRVLHLEMKTEIDQESHLKMKYKASTESEEIE------------------------ 797
P V LE K Q + M + S + +++
Sbjct: 1003 ----PPVCELE-KNYSHQVGNYHMGFLVSEDESKLDPGAAEQVPDFVTFLYQITRGIAAR 1057
Query: 798 GYGMMICK--RIFSERIMLEAYKISEL--LRASKRKGLKIIAKEDSCDNA 843
YG+ + K + E + A+K EL L +KRK LK AK + NA
Sbjct: 1058 SYGLNVAKLADVPGEILKKAAHKSKELEGLINTKRKRLKYFAKLWTMHNA 1107
>At4g02070 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1324
Score = 132 bits (331), Expect = 3e-30
Identities = 170/742 (22%), Positives = 302/742 (39%), Gaps = 74/742 (9%)
Query: 102 TTTSG--LVVGPDRT-IFSIFESGKN-----ADTRVGICVVNYSTAEMHVSEFIDTQVFI 153
T T G L+ PD + + ++ E G++ A+ G+C+V+ +T ++ + +F D Q
Sbjct: 491 TLTDGEMLLTNPDASYLMALTEGGESLTNPTAEHNFGVCLVDVATQKIILGQFKDDQDCS 550
Query: 154 KTLNKIYVCQPTEILIPSHSLSGKVSKLSTIVKC-------NISDNVKICEAATKVY--- 203
+ +P EI+ P+ LS + TIV+ N+ + ++ +Y
Sbjct: 551 ALSCLLSEMRPVEIIKPAKVLSYATER--TIVRQTRNPLVNNLVPLSEFWDSEKTIYEVG 608
Query: 204 ------NPQEGLEVLEKFALLGTNKSPVPFAEQLIGKE-----FCLMAVSAASNYMTQIA 252
N Q + +LG S +P + E L A+ A Y+ Q
Sbjct: 609 IIYKRINCQPSSAYSSEGKILGDGSSFLPKMLSELATEDKNGSLALSALGGAIYYLRQAF 668
Query: 253 EADLALKFSNFR------VRIDNGDNTMLIDMKTVQSLELIENTLESN-GMTLLKVIDKT 305
+ L+F+ F N M++D +++LE+ EN+ TL +++
Sbjct: 669 LDESLLRFAKFESLPYCDFSNVNEKQHMVLDAAALENLEIFENSRNGGYSGTLYAQLNQC 728
Query: 306 VTKMGHRALRNDILQPLTDINSLKLRVSAVQELQN-NPDFLNSFRMELKVLHDLDALFSK 364
+T G R L+ + +PL + +K R AV L+ N + FR L L D++ L ++
Sbjct: 729 ITASGKRLLKTWLARPLYNTELIKERQDAVAILRGENLPYSLEFRKSLSRLPDMERLIAR 788
Query: 365 LLS-FNHTVILPDQKLNYVILLKESIESATTLKRXXXXXXXXXXXXXXIMAXXXXXXXXX 423
+ S + D+ + Y K+ ++ + R I+
Sbjct: 789 MFSSIEASGRNGDKVVLYEDTAKKQVQEFISTLRGCETMAEACSSLRAILKHDTSRRLLH 848
Query: 424 XXX----LIN-----RYLNEDTRWASTPIDLQNQKAYAIKRGSNGLLDVLRQLYKSLTDD 474
L N +Y + W ++ N G++ D + +
Sbjct: 849 LLTPGQSLPNISSSIKYFKDAFDW----VEAHNSGRVIPHEGADEEYDCACKTVEEFESS 904
Query: 475 IMREVDSLRDKFGLNFSHGHDVNRQFYLKLKKKDINQL--SDLDSCFINRVTKKTAYEFT 532
+ + + R G + V + YL + ++ D + C +KK +
Sbjct: 905 LKKHLKEQRKLLGDASINYVTVGKDEYLLEVPESLSGSVPHDYELCS----SKKGVSRYW 960
Query: 533 TLNLMKMNTRLSELTCEMIALSEQTVSELLSNISSHIATLFMISEAISVLDLLCSLATT- 591
T + K+ LS+ E + + L+ H + A + LD+L SLA
Sbjct: 961 TPTIKKLLKELSQAKSEKESALKSISQRLIGRFCEHQEKWRQLVSATAELDVLISLAFAS 1020
Query: 592 ----GLENNWILASFGN----HLSLSGARHPILENTLT---NFVANDVE-AIPNLSSFQI 639
G+ +++ + HLS +G HP+L +FV N+V+ +SF +
Sbjct: 1021 DSYEGVRCRPVISGSTSDGVPHLSATGLGHPVLRGDSLGRGSFVPNNVKIGGAEKASFIL 1080
Query: 640 VTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARV-CNDDIEAYSSTFS 698
+TG NM GKS L+QV + ILAQIG VP + K+ R+ D I A STF
Sbjct: 1081 LTGPNMGGKSTLLRQVCLAVILAQIGADVPAETFEVSPVDKICVRMGAKDHIMAGQSTFL 1140
Query: 699 AEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSK-NATVFLSTHFRD 757
E+ + A + T +L++LDELGRG++ +DG +IA ++ E+ + K F STH+
Sbjct: 1141 TELSETAVMLTSATRNSLVVLDELGRGTATSDGQAIAESVLEHFIEKVQCRGFFSTHYHR 1200
Query: 758 IPKILAPKPRVLHLEMKTEIDQ 779
+ P+V M +I +
Sbjct: 1201 LSVDYQTNPKVSLCHMACQIGE 1222
>YOL090w [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 964
Score = 125 bits (314), Expect = 3e-28
Identities = 140/583 (24%), Positives = 238/583 (40%), Gaps = 62/583 (10%)
Query: 240 AVSAASNYMTQIAEADLALKFSNFRVRIDNGDNTMLIDMKTVQSLELI---------ENT 290
A +A Y+ ++E D K+ ++ M +D +++L L N
Sbjct: 264 ACNALIGYLQLLSEQDQVGKYELVEHKLKE---FMKLDASAIKALNLFPQGPQNPFGSNN 320
Query: 291 LESNGMT----------LLKVIDKTVTKMGHRALRNDILQPLTDINSLKLRVSAVQELQN 340
L +G T L ++++ T G R L + QPLT+I+ + R V L +
Sbjct: 321 LAVSGFTSAGNSGKVTSLFQLLNHCKTNAGVRLLNEWLKQPLTNIDEINKRHDLVDYLID 380
Query: 341 NPDFLNSFRME-LKVLHDLDALFSKLLSFNHTVILPDQKLNYVIL--LKESIESATTLKR 397
+ E L ++ D+ L KL N L D Y + E ++ T+
Sbjct: 381 QIELRQMLTSEYLPMIPDIRRLTKKL---NKRGNLEDVLKIYQFSKRIPEIVQVFTSFLE 437
Query: 398 XXXXXXXXXXXXXXIMAXXXXXXXXXXXXLINRYLNEDTRWASTPIDL---QNQKAYAIK 454
+ L++ T +DL + + IK
Sbjct: 438 DDSPTEPVNELVRSVWLAPLSHHVEP--------LSKFEEMVETTVDLDAYEENNEFMIK 489
Query: 455 RGSNGLLDVLRQLYKSLTDDIMR-EVDSLRD-------KFGLNFSHGHDVNRQFYLKLKK 506
N L +R +L D+I +DS D K L H H + ++L +
Sbjct: 490 VEFNEELGKIRSKLDTLRDEIHSIHLDSAEDLGFDPDKKLKLENHHLHG----WCMRLTR 545
Query: 507 KDINQLSDLDSCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALSEQTVSELLSNIS 566
D +L +I T K F+T L + + L E V E+++
Sbjct: 546 NDAKELRKHKK-YIELSTVKAGIFFSTKQLKSIANETNILQKEYDKQQSALVREIINITL 604
Query: 567 SHIATLFMISEAISVLDLLCSLATTG-------LENNWILASFGNHLSLSGARHPILE-N 618
++ +S ++ LD++ S A T + L +RHP+LE
Sbjct: 605 TYTPVFEKLSLVLAHLDVIASFAHTSSYAPIPYIRPKLHPMDSERRTHLISSRHPVLEMQ 664
Query: 619 TLTNFVANDVEAIPNLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLY 678
+F++NDV F I+TG NM GKS Y++QV +++++AQIGC VPC A +
Sbjct: 665 DDISFISNDVTLESGKGDFLIITGPNMGGKSTYIRQVGVISLMAQIGCFVPCEEAEIAIV 724
Query: 679 QKLHARVCNDDIEAYS-STFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALA 737
+ RV D + STF E+ + A + + + +L+I+DELGRG+S DGF +A A
Sbjct: 725 DAILCRVGAGDSQLKGVSTFMVEILETASILKNASKNSLIIVDELGRGTSTYDGFGLAWA 784
Query: 738 ISEYLLSK-NATVFLSTHFRDIPKILAPKPRVLHLEMKTEIDQ 779
I+E++ SK +THF ++ ++ P V ++ + I++
Sbjct: 785 IAEHIASKIGCFALFATHFHELTELSEKLPNVKNMHVVAHIEK 827
>SPBC24C6.12c [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 434
Score = 120 bits (300), Expect = 1e-26
Identities = 75/193 (38%), Positives = 108/193 (55%), Gaps = 9/193 (4%)
Query: 593 LENNWILASFGNHLSLSGARHPILE-NTLTNFVANDVEAIPNLSSFQIVTGCNMSGKSIY 651
LENN L L ARHP LE F+ NDV S I+TG NM GKS Y
Sbjct: 128 LENNHCA-----RLYLKQARHPCLEAQDDVKFIPNDVNLEHGSSELLIITGPNMGGKSTY 182
Query: 652 LKQVAMLTILAQIGCPVPCTSASFPLYQKLHARVCNDDIEAYS-STFSAEMKDMAYFIDD 710
++QV ++T++AQIGCPVPC A + + ARV D + STF AEM + A +
Sbjct: 183 IRQVGVITVMAQIGCPVPCEVADLDIIDAILARVGASDSQLKGISTFMAEMLETATILRA 242
Query: 711 ITDKTLMILDELGRGSSIADGFSIALAISEYLLSK-NATVFLSTHFRDIPKILAPKPRVL 769
T ++L+I+DELGRG+S DGF +A AI+E+++++ +TH+ ++ K+ V
Sbjct: 243 ATPRSLIIIDELGRGTSTTDGFGLAWAITEHIVTQIGCFCLFATHYHEMTKLSEEITTVK 302
Query: 770 HLEMKTEI-DQES 781
+L + + D ES
Sbjct: 303 NLHVTAYVGDSES 315
>Hs21361940 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 851
Score = 115 bits (288), Expect = 3e-25
Identities = 83/346 (23%), Positives = 171/346 (48%), Gaps = 16/346 (4%)
Query: 511 QLSDLDSCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALSEQTVSELLSNISSHIA 570
+++ LD F++ + + + +++ L +L CE+ + +L + + A
Sbjct: 479 EINGLDFMFLS----EEKLHYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAA 534
Query: 571 TLFMISEAISVLDLLCSLATTGLENNWILASFGNHL---SLSGARHPILENTLTNFVAND 627
L + + S LD+L +LA+ + + + + + RHP++E FV N
Sbjct: 535 VLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELCARTFVPNS 594
Query: 628 VEAIPNLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARVCN 687
E + +++TG N SGKSIYLKQV ++T +A +G VP A + R+ +
Sbjct: 595 TECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHS 654
Query: 688 -DDIEAYSSTFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSKN 746
+ I STF ++ +A +++ T ++L+++DE G+G++ DG ++ A+ + L++
Sbjct: 655 CESISLGLSTFMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARG 714
Query: 747 ---ATVFLSTHFRDIP--KILAPKPRVLHLEMKTEIDQESHLKMKYKASTESEEIEGYGM 801
TVF++T+F + ++L P V +L M+T + + L Y+ +
Sbjct: 715 PTCPTVFVATNFLSLVQLQLLPQGPLVQYLTMET-CEDGNDLVFFYQVCEGVAKASHASH 773
Query: 802 MICKRIFSERIMLEAYKISELLRASKR-KGLKIIAKEDSCDNACQT 846
+ ++++ ++S+L+R+ K K +K + K++ +N CQT
Sbjct: 774 TAAQAGLPDKLVARGKEVSDLIRSGKPIKPVKDLLKKNQMEN-CQT 818
>Hs4505253 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 834
Score = 115 bits (287), Expect = 4e-25
Identities = 82/346 (23%), Positives = 171/346 (48%), Gaps = 16/346 (4%)
Query: 511 QLSDLDSCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALSEQTVSELLSNISSHIA 570
+++ LD F++ + + + +++ L +L CE+ + +L + + A
Sbjct: 462 EINGLDFMFLS----EEKLHYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAA 517
Query: 571 TLFMISEAISVLDLLCSLATTGLENNWILASFGNHL---SLSGARHPILENTLTNFVAND 627
L + + S LD+L +LA+ + + + + + RHP++E FV N
Sbjct: 518 VLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELCARTFVPNS 577
Query: 628 VEAIPNLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARVCN 687
E + +++TG N SGKSIYLKQV ++T +A +G VP A + R+ +
Sbjct: 578 TECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHS 637
Query: 688 -DDIEAYSSTFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSKN 746
+ I STF ++ +A +++ T ++L+++DE G+G++ DG ++ A+ + L++
Sbjct: 638 CESISLGLSTFMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARG 697
Query: 747 AT---VFLSTHFRDIP--KILAPKPRVLHLEMKTEIDQESHLKMKYKASTESEEIEGYGM 801
T +F++T+F + ++L P V +L M+T + + L Y+ +
Sbjct: 698 PTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMET-CEDGNDLVFFYQVCEGVAKASHASH 756
Query: 802 MICKRIFSERIMLEAYKISELLRASKR-KGLKIIAKEDSCDNACQT 846
+ ++++ ++S+L+R+ K K +K + K++ +N CQT
Sbjct: 757 TAAQAGLPDKLVARGKEVSDLIRSGKPIKPVKDLLKKNQMEN-CQT 801
>7298155 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 854
Score = 113 bits (283), Expect = 1e-24
Identities = 101/343 (29%), Positives = 160/343 (46%), Gaps = 31/343 (9%)
Query: 558 VSELLSNISSHIATLFMISEAISVLDLLCSLAT------TGLENNWILASFGNHLSLSGA 611
V E++ + A L +++ ++ LD L S A T +L L L
Sbjct: 513 VEEIIHVAVGYAAPLTLLNNELAQLDCLVSFAIAARSAPTPYVRPKMLEEGARELVLEDV 572
Query: 612 RHPILE-NTLTNFVANDVEAIPNLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPC 670
RHP LE NF+AN V+ + I+TG NM GKS Y++ V ++A IG VPC
Sbjct: 573 RHPCLELQEHVNFIANSVDFKKEECNMFIITGPNMGGKSTYIRSVGTAVLMAHIGAFVPC 632
Query: 671 TSASFPLYQKLHARV-CNDDIEAYSSTFSAEMKDMAYFIDDITDKTLMILDELGRGSSIA 729
+ A+ + + RV +D+I STF EM + + I TDK+L+I+DELGRG+S
Sbjct: 633 SLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVIIDELGRGTSTY 692
Query: 730 DGFSIALAISEYLL--SKNATVFLSTHFRDIPKILAPKPRVLHLEMKTEIDQESHLKMKY 787
+G IA +I+E+L +K T+F +THF +I K+ V + M D + +
Sbjct: 693 EGCGIAWSIAEHLAKETKCFTLF-ATHFHEITKLAETLSTVKNCHMAAVADADDFTLLYQ 751
Query: 788 KASTESEEIEGYGMMICKRI-FSERIM---LEAYKISELLRASKRKGLKIIAKEDSCDNA 843
S E + +G+ + + F E ++ E Y E K+K KED
Sbjct: 752 VRSGVME--KSFGIQVARLANFPEHVVQNAQEVYNEFEDEHVDKQK------KEDK---- 799
Query: 844 CQTTQIKQVYYLVQKLKAFCNHEKTIDIEELRSLQDDFISTFE 886
++++ +Q+L N+ I++E+L L F E
Sbjct: 800 ---ALLEKIQVAIQQLSTAGNN-VDINVEDLTQLVTQFTKDIE 838
>SPCC285.16c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1254
Score = 108 bits (270), Expect = 4e-23
Identities = 77/235 (32%), Positives = 122/235 (51%), Gaps = 7/235 (2%)
Query: 598 ILASFGNHLSLSGARHPILE-NTLTNFVANDVEAIPNLSSFQIVTGCNMSGKSIYLKQVA 656
I+ HL RHP + + + FV NDV + ++TG NM+GKS L+QV
Sbjct: 979 IIEQKDGHLYFEELRHPCINASAASTFVPNDVVLGGESPNMIVLTGPNMAGKSTLLRQVC 1038
Query: 657 MLTILAQIGCPVPCTSASFPLYQKLHARV-CNDDIEAYSSTFSAEMKDMAYFIDDITDKT 715
+ I+AQ+GC VP AS ++ R+ NDDI + STF E+ + +D+ K+
Sbjct: 1039 IAVIMAQLGCWVPAKRASITPMTSIYTRLGANDDIMSARSTFMVELSETKKILDECGPKS 1098
Query: 716 LMILDELGRGSSIADGFSIALAISEYLLSKNATV-FLSTHFRDIPKILAPKPRVLHLEMK 774
L+ILDELGRG+S DG +IA A+ +L+S + F STH++ + +V ++M
Sbjct: 1099 LVILDELGRGTSTYDGHAIAYAVLHHLVSNIGCLGFFSTHYQSLCVDFMHHRQVRLMQMA 1158
Query: 775 TEIDQE-SHLKMKYKASTESEEIEGYGMMICKRIFSERIMLEA--YKISELLRAS 826
+D++ + YK + + YGM + +++A K SEL +AS
Sbjct: 1159 AAVDEKIRRVTFLYKLE-DGICPKSYGMNVASMAGLPEKVIDAAEEKASELEQAS 1212
Score = 54.7 bits (130), Expect = 6e-07
Identities = 53/256 (20%), Positives = 103/256 (39%), Gaps = 25/256 (9%)
Query: 124 NADTRVGICVVNYSTAEMHVSEFIDTQVFIKTLNKIYVCQPTEILIPSHSLSGKVSKLST 183
N + GIC ++ ST H+ EF D K + +P E+++ +S K +
Sbjct: 514 NEEPSFGICFIDTSTGGFHMCEFTDDIHRTKLDTLLTQVRPKELILEKSKISQKSIRA-- 571
Query: 184 IVKCNISDNVKICEAATKVYN---------PQEGLE---VLEKFALLGTNKSPVPFAEQL 231
+K C +++ ++N E +E + + G +P L
Sbjct: 572 ---------IKYCVSSSSIWNFIKPYTEFWDNERVEREIIAGDYFKNGLEGAPKILKSYL 622
Query: 232 IGKEFCLMAVSAASNYMTQIAEADLALKFSNF-RVRIDNGDNTMLIDMKTVQSLELIENT 290
K + A A Y+ Q+ NF ++L++ +T+++LE+ N+
Sbjct: 623 SEKPLAISAFGALFWYLRQLKLDKDMCSMGNFDEYDASQQSTSLLMNGQTLKNLEIFSNS 682
Query: 291 LESNGM-TLLKVIDKTVTKMGHRALRNDILQPLTDINSLKLRVSAVQELQNNPDFLNSFR 349
+ TL ++ + VT G R + PL ++ R+ V+ + +NP ++
Sbjct: 683 FDGGSEGTLFHLLCRCVTPFGKRLFHTWLCHPLRSGTAINARLDVVELIADNPVIRDTIW 742
Query: 350 MELKVLHDLDALFSKL 365
L L DL+ L S++
Sbjct: 743 GFLHKLPDLERLISRV 758
>ECU03g0540 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 730
Score = 108 bits (269), Expect = 5e-23
Identities = 117/465 (25%), Positives = 192/465 (41%), Gaps = 53/465 (11%)
Query: 307 TKMGHRALRNDILQPLTDINSLKLRVSAVQELQNNPDFLNSFRMELKVLHDLDALFSKLL 366
T G R L +LQPL + + ++ R+ V L+ + L +L F LL
Sbjct: 252 TNQGWRLLHRMLLQPLRNKDEIERRLDIVDSLRT---------LNLGILKR----FPDLL 298
Query: 367 SFNHTVILPDQKLNYVILLKESIESATTLKRXXXXXXXXXXXXXXIMAXXXXXXXXXXXX 426
+ V L ++ L +++++ L +
Sbjct: 299 RLSKRVSSGRVSLREILRLAQTVDTIPELMSSFSSSLALSKDVGETLKKIFLAFVP---- 354
Query: 427 LINRYLNEDTRWASTPIDLQ--NQKAYAIKRGSNGLLDVLRQLYKSLTDDIMREVDSLRD 484
+ NE TR IDL+ + Y ++ + L L + + + +E + +
Sbjct: 355 ----FRNEITR----VIDLEAAEENVYRVRPDVSERLQKLNRALAEVDGKMQKEYERV-- 404
Query: 485 KFGLNFSHGHDVNRQFYLKLKKKDINQLSDL--DSCFINRVTKKTAYEFTTLNLMKMNTR 542
G+ D N + K K + + DL F+ K FTT L +N R
Sbjct: 405 -CGIYPRAKVDRNSGAF-KTAKAEYQRSQDLFKKEGFVELSFVKGGVSFTTRVLSLLNER 462
Query: 543 LSELTCEMIALSEQT---VSELLSNISSHIATLFMISEAISVLDLLCSLATTGLENNWIL 599
L E+ ++ V L N + ++ +L ++ + V AT + I+
Sbjct: 463 RESLKKEIDDEEKEIMDGVKTALKNYTPYLESLNHLTALVDVFSAFSIKATLKGYSRPIV 522
Query: 600 ASFGNHLSLSGARHPILENTLTNFVANDVEAIPNLSSFQ-----IVTGCNMSGKSIYLKQ 654
G L + HP+LE D + IPN + +VTG NM GKS +LK
Sbjct: 523 G--GTMLEIENGFHPVLE---------DQDYIPNSIKMEDRRMCVVTGPNMGGKSTFLKT 571
Query: 655 VAMLTILAQIGCPVPCTSASFPLYQKLHARVCNDDIE-AYSSTFSAEMKDMAYFIDDITD 713
++ +LA +GC VP AS P+ ++ RV D SSTF EM D+A +
Sbjct: 572 CGVIALLAHMGCYVPAEYASIPILDGIYTRVGAGDCSFTGSSTFMMEMADIARICRLSSP 631
Query: 714 KTLMILDELGRGSSIADGFSIALAISEYLLSKNATVFLSTHFRDI 758
++L+I+DELGRG+S DG SIA A+ E+L+ K + +THF ++
Sbjct: 632 ESLIIIDELGRGTSAVDGLSIAQAVKEHLILKKSLCLCATHFPEL 676
>Hs4504191 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1360
Score = 105 bits (262), Expect = 3e-22
Identities = 158/718 (22%), Positives = 280/718 (38%), Gaps = 90/718 (12%)
Query: 120 ESGKNADTRV-GICVVNYSTAEMHVSEFIDTQVFIKTLNKIYVCQPTEILIPSHSLSGKV 178
E + TR G+C V+ S + + +F D + + + P ++L +LS +
Sbjct: 546 EEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKET 605
Query: 179 SK-LSTIVKCNISDNV--------------KICEAATKVYNPQEGLEVLEKFALLG-TNK 222
L + + C++ + + + E +G+ V+ L G T++
Sbjct: 606 KTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSE 665
Query: 223 SPVPFAEQLIGKEFCLMAVSAASNYMTQIAEADLALKFSNFRVRIDNGDNT--------- 273
S E L A+ Y+ + L +NF I +T
Sbjct: 666 SDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTTRSGAI 725
Query: 274 -------MLIDMKTVQSLELIEN-TLESNGMTLLKVIDKTVTKMGHRALRNDILQPLTDI 325
M++D T+ +LE+ N T S TLL+ +D T G R L+ + PL +
Sbjct: 726 FTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCAPLCNH 785
Query: 326 NSLKLRVSAVQELQNNPDFLNSFRMELKVLHDLDALFSKLLSFNHTVILPDQKLNY---- 381
++ R+ A+++L PD ++ LK L DL+ L SK+ H V P + N+
Sbjct: 786 YAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKI----HNVGSPLKSQNHPDSR 841
Query: 382 VILLKESIESATTLKRXXXXXXXXXXXXXXIMAXXXXXXXXXXXXLINRYL--------- 432
I+ +E TT + +M ++ L
Sbjct: 842 AIMYEE-----TTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTK 896
Query: 433 NEDTRWASTPIDLQ-------NQKAYAI-----KRGSNGLLDVLRQLYKSLTDDIMREVD 480
N + R+ ++L ++KA K G + D + ++ ++
Sbjct: 897 NPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLE 956
Query: 481 SLRDKFGLNFSHGHDVNRQFYLKLKKKDINQLSDLDSCFINRVTKKTAYEFTTLNLMKMN 540
R++ G + R Y +L+ + +L + + TKK + T + K
Sbjct: 957 KQRNRIGCRTIVYWGIGRNRY-QLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKL 1015
Query: 541 TRLSELTCEMIALSEQTVSELLSNISSHIATLFMISEAISVLDLLCSLATTGLENNWILA 600
L + + L N + E I+VLD+L LA + +
Sbjct: 1016 ANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMC 1075
Query: 601 --------SFGNHLSLSGARHPILENTL--TNFVANDV------EAIPNLSSFQI-VTGC 643
L L G+RHP + T +F+ ND+ E N ++ + VTG
Sbjct: 1076 RPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGP 1135
Query: 644 NMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARV-CNDDIEAYSSTFSAEMK 702
NM GKS ++Q +L ++AQ+GC VP ++ R+ +D I + STF E+
Sbjct: 1136 NMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELS 1195
Query: 703 DMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLS--KNATVFLSTHFRDI 758
+ A + T +L+++DELGRG++ DG +IA A+ + L K T+F STH+ +
Sbjct: 1196 ETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLF-STHYHSL 1252
>ECU10g0710 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 922
Score = 100 bits (249), Expect = 1e-20
Identities = 74/265 (27%), Positives = 115/265 (42%), Gaps = 12/265 (4%)
Query: 495 DVNRQFYLKLKKKDINQLSDLDSCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALS 554
DV + + K+I SD + + K + + +L K+ R E +
Sbjct: 600 DVGKDVFQMEVPKEIGVPSD----YFIMSSVKGVNRYYSRDLRKLVERYMECEERIFQSK 655
Query: 555 EQTVSELLSNISSHIATLFMISEAISVLDLLCSLATTGLENNWILASFGNHLSLSGARHP 614
+ + + H+ + ++ +D S AT N F L SG P
Sbjct: 656 GSLLRRAIDVLLPHVIFFRQVFCELAQIDCYLSFATFSQRNRTSTPVFSTKLCFSGMSSP 715
Query: 615 ILENTLTNFVANDVEAIPNLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSAS 674
I FV ND + + ++TG NM GKS L+ + IL+Q+G V C
Sbjct: 716 IYPA----FVENDYDGCRRIL---VLTGANMGGKSTLLRTICFNVILSQVGMDVCCKRME 768
Query: 675 FPLYQKLHARV-CNDDIEAYSSTFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFS 733
PL+ ++ R+ DD+ STF E+ + + + T +L+I+DELGRG+S DG
Sbjct: 769 TPLFDRIFTRIGARDDLAKGESTFMIELGETSNILRHSTRDSLVIMDELGRGTSTKDGGC 828
Query: 734 IALAISEYLLSKNATVFLSTHFRDI 758
IA A+ EYL K V STH+ I
Sbjct: 829 IARAVLEYLKKKECHVLFSTHYHGI 853
>At4g25540 [L] KOG0218 Mismatch repair MSH3
Length = 1076
Score = 97.8 bits (242), Expect = 6e-20
Identities = 71/227 (31%), Positives = 112/227 (49%), Gaps = 26/227 (11%)
Query: 543 LSELTCEMIALSEQTVSELLSNISSHIATLFMISEAISVLDLLCSLATTGLENNWILASF 602
L+ T + ++ + L + S + +A++ LD L SL+T N++ F
Sbjct: 725 LALATEHLAIVNRASWDSFLKSFSRYYTDFKAAVQALAALDCLHSLSTLSRNKNYVRPEF 784
Query: 603 GN-----HLSLSGARHPILENTLT-NFVANDVEAIPNLSSFQIVTGCNMSGKSIYLKQVA 656
+ +++ RHP+LE L NFV ND QI+TG NM GKS Y++QVA
Sbjct: 785 VDDCEPVEINIQSGRHPVLETILQDNFVPNDTILHAEGEYCQIITGPNMGGKSCYIRQVA 844
Query: 657 MLTILAQIGCPVPCTSASFPLYQKLHARV-CNDDIEAYSSTFSAEMKDMAYFIDDITDKT 715
+++I+AQ+G VP + A + + R+ +D I+ STF E
Sbjct: 845 LISIMAQVGSFVPASFAKLHVLDGVFTRMGASDSIQHGRSTFLEE--------------- 889
Query: 716 LMILDELGRGSSIADGFSIALAISEYLLS-KNATVFLSTHFRDIPKI 761
L+ELGRG+S DG +IA A ++LL+ K V TH+ +I +I
Sbjct: 890 ---LNELGRGTSTHDGVAIAYATLQHLLAEKRCLVLFVTHYPEIAEI 933
>CE28985 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1186
Score = 96.7 bits (239), Expect = 1e-19
Identities = 103/405 (25%), Positives = 173/405 (42%), Gaps = 24/405 (5%)
Query: 453 IKRGSNGLLDVLRQLYKSLTDDIMREVDSLRDKFGLNFSHGHDVNRQFYLKLKKKDINQL 512
+K N L D + K + I + VDS + K+ L V+ F LK ++K +
Sbjct: 779 VKEALNELNDYKDSVAKKYSCSI-KFVDSGKVKYLLEMPENTKVSSSFELKSRRKGFIRY 837
Query: 513 SDLDSCFINRVTKKTAYEFTTLNLMKMNTRLSELTCEMIALSEQTVSELLSNISSH-IAT 571
S DS + A + K+ + E E + +SS + T
Sbjct: 838 STPDSEQL-----VAALDAVEKEKSKLGDDATRRVFEQFGHKNPIWLETVKLVSSFDVLT 892
Query: 572 LFMISEAISVLDLLCSLATTGLENNWILASFGNHLSLS-GARHPILENTLTNFVANDVEA 630
+ S ++ + +++ G H L+ +R+ + + T +F+AN
Sbjct: 893 SLALFAKSSPFEMCMPEFDFNATDPYLIVDKGVHPCLALQSRNEVTQTT--SFIANSTTM 950
Query: 631 IPNLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARV-CNDD 689
+ ++ ++TG NM GKS ++Q A+L ILA IG VP S ++ R+ ND
Sbjct: 951 GASEAAVMLLTGPNMGGKSTLMRQTAVLAILAHIGSMVPAFSMRLTPIDRIFTRIGANDR 1010
Query: 690 IEAYSSTFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSKNA-T 748
I STF E+K+ + + T +L+++DELGRG+S DG +IA A+ + + A
Sbjct: 1011 IMCGESTFFIELKETDIMLKNATKHSLLLVDELGRGTSTFDGTAIASAVLQKISDDLACR 1070
Query: 749 VFLSTHFRDIPKILAPKPRVLHLEMKTEIDQESHLKMKYKASTESEEIE------GYGMM 802
F STH+ I P V MK +D+E++ + T E+E YG
Sbjct: 1071 TFFSTHYHSICDSFTNHPNVRLAHMKCVVDKENNEDPTMEDVTFLYELESGICPKSYGFY 1130
Query: 803 ICKRI-FSERIMLEAYK-----ISELLRASKRKGLKIIAKEDSCD 841
K +++ AY S L+ K + L A++D+ D
Sbjct: 1131 AAKLAGIDHQVVRNAYLESNKFASNLIIDPKIRHLVECARDDNFD 1175
Score = 51.6 bits (122), Expect = 5e-06
Identities = 35/110 (31%), Positives = 59/110 (52%), Gaps = 8/110 (7%)
Query: 266 RIDNGDNTMLIDMKTVQSLELIENTLESNGMTLLKVIDKTVTKMGHRALRNDILQPLTDI 325
+ID +++D +++L ++ N +S+ +L VI+K T G R LR+ +LQP D
Sbjct: 563 KIDWNGKNLILDGTALENLNIVPNGRDSHLTSLYYVINKCSTPFGRRLLRSWLLQPTCDP 622
Query: 326 NSLKLRVSAVQELQNNPD---FLNSFRMELKVLHDLDALFSKLLSFNHTV 372
L+ R A++ L +PD F+ + LK + DLD L K+ HT+
Sbjct: 623 KKLEQRQKAIKWLV-SPDASSFMTTATATLKKIPDLDRLLQKI----HTI 667
>YDL154w [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 901
Score = 85.1 bits (209), Expect = 4e-16
Identities = 117/543 (21%), Positives = 212/543 (38%), Gaps = 85/543 (15%)
Query: 274 MLIDMKTVQSLELI--------ENTLESNGMTLLKVIDKTVTKMGHRALRNDILQPLTDI 325
M++D T+ +L + + + + ++ ++ ++ + R L++ ++ PLT+
Sbjct: 247 MVLDENTISALHIFPTAHKLGHDKMMRNGFFSVFELFNQVSSDYARRILKSWLINPLTNK 306
Query: 326 NSLKLRVSAVQEL--QNNPDFLNSFRMELKVLHDLDALFSKLLSFNHTVILPDQKLNYVI 383
++ R S ++ L + N + +K D ++L S T+ + +++
Sbjct: 307 KRIETRYSIIRTLLDKQNAIIFSDLSQSIKRCPDAFGFINQLRSGKSTLGTWSKVASFLE 366
Query: 384 LLKESIESATTLKRXXXXXXXXXXXXXXIMAXXXXXXXXXXXXLINRYLNEDTRWASTPI 443
+ ++LK + L E R T I
Sbjct: 367 KGIAIFQLVSSLKLGSDEANILHDIKNKVDISA---------------LKECLRKVETVI 411
Query: 444 DL---QNQKAYAIKRGSNGLLDVLRQLYKSLTDDIMREVDSLRDKFGLNFSHGHDVNRQF 500
D ++ K I G + LD R +Y L + I+ +V F LN D
Sbjct: 412 DFDTSRDTKTLTINTGVDNRLDECRNIYNHL-EGILLDVARETQIFLLNTMPQEDCKTT- 469
Query: 501 YLKLKKKDINQ-----------LSDLDSCFINRVTKKTAYEF--TTLNLMKMNTRLSELT 547
K +K +N +S L ++ + E ++ N+ N R+ EL
Sbjct: 470 --KSLEKLVNAVYIPQLGYLVTISVLMEPLLDGIPNLQWEEIFRSSENIYFKNGRVLEL- 526
Query: 548 CEMIALSEQTVSELLSNISS-HIATLFMISEAI--------------SVLDLLCSLATTG 592
++T ++ IS I LF + E I S L++L S A
Sbjct: 527 -------DETYGDIYGAISDFEIEILFSLQEQILRRKTQLTAYNILLSELEILLSFAQVS 579
Query: 593 LENNWI---LASFGNHLSLSGARHPILENTLTNFVANDVEAIPNLSS-----------FQ 638
E N+ L L + RH + E L N++ N L S
Sbjct: 580 AERNYAEPQLVEDECILEIINGRHALYETFLDNYIPNSTMIDGGLFSELSWCEQNKGRII 639
Query: 639 IVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQKLHARV-CNDDIEAYSSTF 697
+VTG N SGKS+YL Q ++ LAQIGC VP A + K+ R+ + + S+F
Sbjct: 640 VVTGANASGKSVYLTQNGLIVYLAQIGCFVPAERARIGIADKILTRIRTQETVYKTQSSF 699
Query: 698 SAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSI--ALAISEYLLSKNATVFLSTHF 755
+ + MA + T+K+L+++DE G+G+ I DG S+ ++ ++ K + THF
Sbjct: 700 LLDSQQMAKSLSLATEKSLILIDEYGKGTDILDGPSLFGSIMLNMSKSEKCPRIIACTHF 759
Query: 756 RDI 758
++
Sbjct: 760 HEL 762
>At3g20475 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 321
Score = 82.8 bits (203), Expect = 2e-15
Identities = 62/214 (28%), Positives = 103/214 (47%), Gaps = 27/214 (12%)
Query: 594 ENNWI--LASFGNHLSLSGARHPILENTLTNFVANDVEAIPNLSSFQIVTGCNMSGKSIY 651
+NN++ + + + L + RH + E + F+ ND E N I+TG N SGKSIY
Sbjct: 33 QNNYVRPVLTVESLLDIRNGRHVLQEMAVDTFIPNDTEINDN-GRIHIITGPNYSGKSIY 91
Query: 652 LKQVAMLTILAQIGCPVPCTSASFPLYQKLHARVCNDDIEAYSSTFSAEMKDMAYFIDDI 711
+KQVA++ L+ IG VP +A+ L ++ + + + A STF ++ + +
Sbjct: 92 VKQVALIVFLSHIGSFVPADAATVGLTDRIFCAMGSKFMTAEQSTFMIDLHQVGMMLRQA 151
Query: 712 TDKTLMILDELGRGSSIADGFSIALAISEYLLSKNATVFLSTHFRDIPKILAPKPRVLHL 771
T ++L +LDE G+G+ DG + T+ +HF A PRV+
Sbjct: 152 TSRSLCLLDEFGKGTLTEDGIGLL----------GGTI---SHF----ATCAEPPRVVVC 194
Query: 772 EMKTEIDQESHLKMKYKASTESEEIEGYGMMICK 805
TE+ ES L + SE+I+ Y M + +
Sbjct: 195 THLTELLNESCLPV-------SEKIKFYTMSVLR 221
>CE26678 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 1369
Score = 82.4 bits (202), Expect = 3e-15
Identities = 58/258 (22%), Positives = 119/258 (45%), Gaps = 9/258 (3%)
Query: 538 KMNTRLSELTCEMIALSEQTVSELLSNISSHIATLFMISEAISVLDLLCSLATTGLENNW 597
+++ ++ +I + L + + ++ + S +D+L S +N W
Sbjct: 532 RLDDEFGDILMRLIDSQTAIILTLKTRVMKKKRSIIKLLSIASRIDVLISFGLIAAQNGW 591
Query: 598 ILASFGNHLSLSGAR--HPILENTLT-NFVANDVEAIPNLSSFQIVTGCNMSGKSIYLKQ 654
+ + + HPI + +FV N V + + I+TG N GKS+Y+K
Sbjct: 592 NCPALVDEPVIEAVELYHPISVLVVKKSFVPNQVSSGRDGIKASIITGPNACGKSVYMKS 651
Query: 655 VAMLTILAQIGCPVPCTSASFPLYQKLHARVCN-DDIEAYSSTFSAEMKDMAYFIDDITD 713
+ ++ L+ IG VP A + ++ R+ D + STF+ +++ +A + T
Sbjct: 652 IGIMVFLSHIGSFVPARHAKIGIVDRIVTRMFTVDSVLDGMSTFAKDVEQVALALRKATG 711
Query: 714 KTLMILDELGRGSSIADGFSIALAISEYLLSKNAT----VFLSTHFRDIPKILAPKPRVL 769
+L+I+DE G+G+ G S+ ++ Y +++ A +FLS+HF +P + + +
Sbjct: 712 NSLVIIDEFGKGTMTEVGLSLLASVMTYWMNRGADRCPHIFLSSHFHALPNYIPLETNIA 771
Query: 770 HLEMKTEIDQESHLKMKY 787
T + +E+ K+KY
Sbjct: 772 TFLTFTVL-REAGGKIKY 788
>At3g24320 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1022
Score = 64.3 bits (155), Expect = 8e-10
Identities = 50/188 (26%), Positives = 80/188 (41%), Gaps = 25/188 (13%)
Query: 573 FMISEAISVLDLLCSLATTGLENNWILASFGNHLSLSGARHPILENTLTNFVANDVEAIP 632
F + E LD + TGL W S G + NT+
Sbjct: 625 FSLDEGAKPLDGASRMKLTGLSPYWFDVSSGT----------AVHNTV------------ 662
Query: 633 NLSSFQIVTGCNMSGKSIYLKQVAMLTILAQIGCPVPCTSASFPLYQK--LHARVCNDDI 690
++ S ++TG N GKS L+ + +L G VP SA P + LH + + +
Sbjct: 663 DMQSLFLLTGPNGGGKSSLLRSICAAALLGISGLMVPAESACIPHFDSIMLHMKSYDSPV 722
Query: 691 EAYSSTFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSKNATVF 750
+ SS F EM ++ + T ++L+++DE+ RG+ A G IA ++ E L +
Sbjct: 723 DGKSS-FQVEMSEIRSIVSQATSRSLVLIDEICRGTETAKGTCIAGSVVESLDTSGCLGI 781
Query: 751 LSTHFRDI 758
+STH I
Sbjct: 782 VSTHLHGI 789
>At3g18525 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 422
Score = 60.1 bits (144), Expect = 1e-08
Identities = 57/253 (22%), Positives = 113/253 (44%), Gaps = 11/253 (4%)
Query: 115 IFSIFESGKNADTRVGICVVNYSTAEMHVSEFIDTQVFIKTLNKIYVCQPTEILIPSHSL 174
+ SIF S + +G+ V+ + + ++EF+D F + + E + P+ S
Sbjct: 144 VVSIFPSFHDGRCVIGMAYVDLTRRVLGLAEFLDDSRFTNLESSLIALGAKECIFPAES- 202
Query: 175 SGKVSKLSTIVKCNISDNVKICEAATKVYNPQEGLEVLEKFALLGTNKSPVPFAEQLIGK 234
GK ++ ++ V I E + ++ L++ L+ N PV + + G
Sbjct: 203 -GKSNECKSLYDSLERCAVMITERKKHEFKGRDLDSDLKR--LVKGNIEPV--RDLVSGF 257
Query: 235 EFCLMAVSAASNYMTQIAEADLALKFSNFRVRIDNGDNTMLIDMKTVQSLELIENTLESN 294
+ A+ A ++ ++ D + NF +R + M +D +++L ++E+ ++N
Sbjct: 258 DLATPALGALLSFSELLSNED---NYGNFTIRRYDIGGFMRLDSAAMRALNVMESKTDAN 314
Query: 295 -GMTLLKVIDKTVTK-MGHRALRNDILQPLTDINSLKLRVSAVQELQNNPDFLNSFRMEL 352
+L ++++T T MG R L + QPL D+N +K R+ VQ R L
Sbjct: 315 KNFSLFGLMNRTCTAGMGKRLLHMWLKQPLVDLNEIKTRLDIVQCFVEEAGLRQDLRQHL 374
Query: 353 KVLHDLDALFSKL 365
K + D++ L L
Sbjct: 375 KRISDVERLLRSL 387
>CE04858 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 107
Score = 59.3 bits (142), Expect = 3e-08
Identities = 33/100 (33%), Positives = 52/100 (52%)
Query: 687 NDDIEAYSSTFSAEMKDMAYFIDDITDKTLMILDELGRGSSIADGFSIALAISEYLLSKN 746
ND++ S F++EM D A + +L++LDEL R +S +G +I AI E +L +
Sbjct: 4 NDELIRNKSAFASEMSDAAAIVQYADKNSLVVLDELARSTSTEEGIAITYAICEKVLKLH 63
Query: 747 ATVFLSTHFRDIPKILAPKPRVLHLEMKTEIDQESHLKMK 786
+ FL+THF DI + + + +ID S K K
Sbjct: 64 SYTFLATHFLDIAALANYSNAIDNYHFLPQIDDNSTKKHK 103
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.132 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,921,069
Number of Sequences: 60738
Number of extensions: 1751812
Number of successful extensions: 5282
Number of sequences better than 1.0e-05: 29
Number of HSP's better than 0.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 5185
Number of HSP's gapped (non-prelim): 45
length of query: 888
length of database: 30,389,216
effective HSP length: 115
effective length of query: 773
effective length of database: 23,404,346
effective search space: 18091559458
effective search space used: 18091559458
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)