ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2919 good I KOG0831 Lipid transport and metabolism Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2919 1030159 1031394 412
(412 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR245c [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT) 396 e-110
Hs17157995 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (... 188 1e-47
CE18794 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT) 186 5e-47
CE27391 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT) 185 1e-46
Hs14211871 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (... 184 2e-46
CE25428 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT) 174 3e-43
CE14392 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT) 160 4e-39
7304165 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT) 148 2e-35
Hs18595884 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (... 139 6e-33
SPCC1235.15 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase ... 132 7e-31
7304166 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT) 128 2e-29
Hs18595888 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (... 121 2e-27
7304164 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT) 120 5e-27
SPCC548.01 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (... 112 1e-24
Hs13376662 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (... 109 9e-24
Hs22058366 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (... 105 2e-22
At3g51520 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (D... 99 1e-20
>YOR245c [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 418
Score = 396 bits (1018), Expect = e-110
Identities = 188/372 (50%), Positives = 259/372 (69%), Gaps = 3/372 (0%)
Query: 40 CAIDTPIERRLQTLSVAWYVECIPLMIIIMLFVWVNPLMWSFVIPYTIYYFIDRTASNGN 99
C + TP ERRLQTL+VAW+ L I LF P +W IPY IY+F DR+ + G
Sbjct: 49 CPLATPFERRLQTLAVAWHTSSFVLFSIFTLFAISTPALWVLAIPYMIYFFFDRSPATGE 108
Query: 100 AVKRHSKWFRSLKVWFYFRDYFPISMHKSTELEPTFTSIDSTELENDASEPGYLDSSQPV 159
V R+S FRSL +W ++ DYFPIS+ K+ L+PTFT + + N+ + L ++
Sbjct: 109 VVNRYSLRFRSLPIWKWYCDYFPISLIKTVNLKPTFT-LSKNKRVNEKNYKIRLWPTKYS 167
Query: 160 LPDKWWNPFREKDETVRPTGPRYIFGYHPHXXXXXXXXXXXXTEACNWSKVFPGIPVCLL 219
+ K + +++ TGP Y+FGYHPH TE CN+SK+FPGIP+ L+
Sbjct: 168 INLKSNSTIDYRNQEC--TGPTYLFGYHPHGIGALGAFGAFATEGCNYSKIFPGIPISLM 225
Query: 220 TLVNQFQIPVYRDYLLALGITSVARKNAMKVLEKNYSIAIVIGGASESLLTNLGSSDIIL 279
TLV QF IP+YRDYLLALGI+SV+RKNA++ L KN SI IV+GGA ESLL++ + +IL
Sbjct: 226 TLVTQFHIPLYRDYLLALGISSVSRKNALRTLSKNQSICIVVGGARESLLSSTNGTQLIL 285
Query: 280 SKRKGFVKLALQTGNVSLVPVYGFGETDTYKILKLKNDSIIGRIQIWLKENYSFTVPLFF 339
+KRKGF+KLA+QTGN++LVPV+ FGE D Y +L K DS++G++Q+W KEN+ FT+P+F+
Sbjct: 286 NKRKGFIKLAIQTGNINLVPVFAFGEVDCYNVLSTKKDSVLGKMQLWFKENFGFTIPIFY 345
Query: 340 ARGVFNYDFGLLPFRHPVNVVVGNPIHIKEKIDHPTIEEIDHYHSLYIEELKRLYDDNKA 399
ARG+FNYDFGLLPFR P+NVVVG PI++++KI +P + ++H+H LYI ELKRLY +N+
Sbjct: 346 ARGLFNYDFGLLPFRAPINVVVGRPIYVEKKITNPPDDVVNHFHDLYIAELKRLYYENRE 405
Query: 400 KFNYSEKTLNIV 411
K+ + L IV
Sbjct: 406 KYGVPDAELKIV 417
>Hs17157995 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 334
Score = 188 bits (478), Expect = 1e-47
Identities = 119/378 (31%), Positives = 195/378 (51%), Gaps = 60/378 (15%)
Query: 36 KPEFCAIDTPIERRLQTLSVAWYVECI---PLMIIIMLFVWVNPLMWSFVIPYTIYYFID 92
K EF ++ + RRLQT++V +V P+ I I + + ++ ++ + IPY ++ + D
Sbjct: 2 KVEFAPLNIQLARRLQTVAVLQWVLSFLTGPMSIGITVMLIIHNYLFLY-IPYLMWLYFD 60
Query: 93 -RTASNGNAVKRHSKWFRSLKVWFYFRDYFPISMHKSTELEPTFTSIDSTELENDASEPG 151
T G R S W ++ +W +F+DYFPI + K+ +L+P+
Sbjct: 61 WHTPERGG---RRSSWIKNWTLWKHFKDYFPIHLIKTQDLDPSHN--------------- 102
Query: 152 YLDSSQPVLPDKWWNPFREKDETVRPTGPRYIFGYHPHXXXXXXXXXXXXTEACNWSKVF 211
YIFG+HPH ++ +F
Sbjct: 103 ------------------------------YIFGFHPHGIMAVGAFGNFSVNYSDFKDLF 132
Query: 212 PGIPVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLEK----NYSIAIVIGGASES 267
PG L L F PV+R+Y++++G+ SV++K+ ++ K N S+ IV+GGA ES
Sbjct: 133 PGFTSYLHVLPLWFWCPVFREYVMSVGLVSVSKKSVSYMVSKEGGGNISV-IVLGGAKES 191
Query: 268 LLTNLGSSDIILSKRKGFVKLALQTGNVSLVPVYGFGETDTYKILKLKNDSIIGRIQIWL 327
L + G + + +RKGFVK+AL G SLVPV FGE + +K S I +Q L
Sbjct: 192 LDAHPGKFTLFIRQRKGFVKIALTHG-ASLVPVVSFGENELFKQTDNPEGSWIRTVQNKL 250
Query: 328 KENYSFTVPLFFARGVFNYDFGLLPFRHPVNVVVGNPIHIKEKIDHPTIEEIDHYHSLYI 387
++ F +PLF ARGVF Y+FGL+ +R ++ VVG PI +++ + +PT E+I+ H Y+
Sbjct: 251 QKIMGFALPLFHARGVFQYNFGLMTYRKAIHTVVGRPIPVRQTL-NPTQEQIEELHQTYM 309
Query: 388 EELKRLYDDNKAKFNYSE 405
EEL++L++++K K+ E
Sbjct: 310 EELRKLFEEHKGKYGIPE 327
>CE18794 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 345
Score = 186 bits (472), Expect = 5e-47
Identities = 114/358 (31%), Positives = 174/358 (47%), Gaps = 54/358 (15%)
Query: 55 VAWYVECIPLMIIIML--FVWVNPLMWSFVIPYTIYYFIDRTASNGNAVKRHSKWFRSLK 112
V W+ P + + FV W + Y ++Y DR + + WFR+L
Sbjct: 32 VVWFGLIYPFCCLCQVAPFVLFFTGQWIILGLYAVWYLYDRESPRRGGYR--DNWFRNLS 89
Query: 113 VWFYFRDYFPISMHKSTELEPTFTSIDSTELENDASEPGYLDSSQPVLPDKWWNPFREKD 172
+ +F +YFP+ +HK+ EL+P
Sbjct: 90 LHKWFAEYFPVKLHKTAELDPN-------------------------------------- 111
Query: 173 ETVRPTGPRYIFGYHPHXXXXXXXXXXXXTEACNWSKVFPGIPVCLLTLVNQFQIPVYRD 232
Y+FGYHPH +ACN +VF GI + TL F R+
Sbjct: 112 -------QNYLFGYHPHGILGVGAWSCFGFDACNVKQVFKGIRFNICTLPGNFTAMFRRE 164
Query: 233 YLLALGITSVARKNAMKVL---EKNYSIAIVIGGASESLLTNLGSSDIILSKRKGFVKLA 289
LL++G+ ++++ VL EK ++ IV+GGA+E+L + G + L+ RKGFV+ A
Sbjct: 165 ILLSIGMIESSKESIEHVLNSEEKGRAVVIVVGGAAEALEAHPGKHTLTLANRKGFVREA 224
Query: 290 LQTGNVSLVPVYGFGETDTYKILKLKNDSIIGRIQIWLKENYSFTVPLFFARGVFNYDFG 349
++TG LVPVY FGE D YK + S + +IQ W K+ ++PL + RG F G
Sbjct: 225 VKTG-AHLVPVYAFGENDIYKQIDNPEGSKLRKIQEWGKKKMGISLPLIYGRGYFQMALG 283
Query: 350 LLPFRHPVNVVVGNPIHIKEKIDHPTIEEIDHYHSLYIEELKRLYDDNKAKFNYSEKT 407
LLP VNVVVG PI +++++D P+ E ID H +Y+E+L L++++KAKF S+ T
Sbjct: 284 LLPMSRAVNVVVGAPIQVEKELD-PSKEVIDEIHGVYMEKLAELFEEHKAKFGVSKDT 340
>CE27391 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 349
Score = 185 bits (469), Expect = 1e-46
Identities = 113/380 (29%), Positives = 180/380 (46%), Gaps = 55/380 (14%)
Query: 38 EFCAIDTPIERRLQTLSVAWYVECI---PLMIIIMLFVWVNPLMWSFVIPYTIYYFIDRT 94
E+ ++ P+ RRLQTL + P++++ + F + ++W + Y ++ D
Sbjct: 18 EWAPLNIPLARRLQTLGALHFFFITLFTPVLVLTVPFYMLYTVLWPLIFLYGLWMIYDWN 77
Query: 95 ASNGNAVKRHSKWFRSLKVWFYFRDYFPISMHKSTELEPTFTSIDSTELENDASEPGYLD 154
+ A S WF+ ++ ++ +YFP+ +H ++++
Sbjct: 78 SPKKGAYM--SNWFQRQRIHSWYANYFPVKLHTTSDM----------------------- 112
Query: 155 SSQPVLPDKWWNPFREKDETVRPTGPRYIFGYHPHXXXXXXXXXXXXTEACNWSKVFPGI 214
P Y+ GYHPH T P I
Sbjct: 113 ----------------------PEEHNYLIGYHPHGIISMAAFINFATNGTGILDTLPRI 150
Query: 215 PVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLE---KNYSIAIVIGGASESLLTN 271
L TLV QF P R++ L G+ +R++ VLE K ++ +V+GGA E+L +
Sbjct: 151 RFHLCTLVGQFWTPWRREWGLLHGMIDCSRESIKHVLEHEKKGKAVVLVVGGAEEALDAH 210
Query: 272 LGSSDIILSKRKGFVKLALQTGNVSLVPVYGFGETDTYKILKLKNDSIIGRIQIWLKENY 331
G + L KRKGFVK+ALQTG LVP Y FGE D + + S I + Q +K
Sbjct: 211 PGCHILTLKKRKGFVKIALQTG-AQLVPCYSFGENDIFNQAENPKGSTIRQFQTIMKRVL 269
Query: 332 SFTVPLFFARGVFNYDFGLLPFRHPVNVVVGNPIHIKEKIDHPTIEEIDHYHSLYIEELK 391
F+ P F+ RGVFNY FGLLPFR P+N V+G PI + + + +PT E+ID H Y++ L
Sbjct: 270 GFSPPAFYGRGVFNYTFGLLPFRKPINTVLGAPISVTKTV-NPTQEQIDTLHQTYMDRLH 328
Query: 392 RLYDDNKAKFNYSEKTLNIV 411
L++++K K++ S T ++
Sbjct: 329 ELFEEHKTKYDVSPTTQLVI 348
>Hs14211871 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 297
Score = 184 bits (467), Expect = 2e-46
Identities = 121/332 (36%), Positives = 164/332 (48%), Gaps = 55/332 (16%)
Query: 79 WSFVIPYTIYYFID-RTASNGNAVKRHSKWFRSLKVWFYFRDYFPISMHKSTELEPTFTS 137
W + Y + D T G R S+W R+ VW YFRDYFPI + K+ L T
Sbjct: 9 WLIAVLYFTWLVFDWNTPKKGG---RRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTT--- 62
Query: 138 IDSTELENDASEPGYLDSSQPVLPDKWWNPFREKDETVRPTGPRYIFGYHPHXXXXXXXX 197
YIFGYHPH
Sbjct: 63 ------------------------------------------RNYIFGYHPHGIMGLGAF 80
Query: 198 XXXXTEACNWSKVFPGIPVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLEKNYS- 256
TEA SK FPGI L TL F++PV R+YL++ GI V+R +L KN S
Sbjct: 81 CNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVSRDTIDYLLSKNGSG 140
Query: 257 --IAIVIGGASESLLTNLGSSDIILSKRKGFVKLALQTGNVSLVPVYGFGETDTYKILKL 314
I IV+GGA+ESL + G + + L RKGFVKLAL+ G LVP+Y FGE + YK +
Sbjct: 141 NAIIIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHG-ADLVPIYSFGENEVYKQVIF 199
Query: 315 KNDSIIGRIQIWLKENYSFTVPLFFARGVFNYD-FGLLPFRHPVNVVVGNPIHIKEKIDH 373
+ S +Q ++ F +F RG+F+ D +GL+P+ P+ VVG PI I K++H
Sbjct: 200 EEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITI-PKLEH 258
Query: 374 PTIEEIDHYHSLYIEELKRLYDDNKAKFNYSE 405
PT ++ID YH++Y+E L +L+D +K KF E
Sbjct: 259 PTQQDIDLYHTMYMEALVKLFDKHKTKFGLPE 290
>CE25428 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 340
Score = 174 bits (440), Expect = 3e-43
Identities = 117/387 (30%), Positives = 180/387 (46%), Gaps = 62/387 (16%)
Query: 37 PEFCAID-----TPIERRLQTLSVAWYVEC---IPLMIIIMLFVWVNPLMWSFVIPYTIY 88
P+F I+ + I+R+ L V ++ + L + I+ F + W + Y +
Sbjct: 2 PQFLGIEWVDLFSSIQRKKTYLGVVYHFMLTYPLALFVTILPFFLLFTFQWHILALYACW 61
Query: 89 YFIDRTASNGNAVKRHSKWFRSLKVWFYFRDYFPISMHKSTELEPTFTSIDSTELENDAS 148
YF D + S W R +V +F YFPI++HK+ EL
Sbjct: 62 YFYDMDSPRRGGYS--SDWVRKWRVNDWFAQYFPINLHKTAELS---------------- 103
Query: 149 EPGYLDSSQPVLPDKWWNPFREKDETVRPTGPRYIFGYHPHXXXXXXXXXXXXTEACNWS 208
T Y+ G HPH T
Sbjct: 104 -----------------------------TDKNYLVGIHPHGIISMAAWSNFATNGTGIY 134
Query: 209 KVFPGIPVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLEK----NYSIAIVIGGA 264
+ FPGI L TL QF++ + R+ LL G+ +R++ VL+K ++ +VIGGA
Sbjct: 135 EKFPGIRWNLCTLALQFRMAIRRELLLLTGLIDCSRESIEYVLDKCGQKGRAVVLVIGGA 194
Query: 265 SESLLTNLGSSDIILSKRKGFVKLALQTGNVSLVPVYGFGETDTYKILKLKNDSIIGRIQ 324
E+L + G + L+ RKGFV+ AL TG LVPVY FGE D ++ ++ S + Q
Sbjct: 195 EEALDAHPGYHTLTLASRKGFVREALITG-AYLVPVYSFGENDVFEQMENPVGSRLRNFQ 253
Query: 325 IWLKENYSFTVPLFFARGVFNYDFGLLPFRHPVNVVVGNPIHIKEKIDHPTIEEIDHYHS 384
W K + + P+F RG F FG LPFR P++ VVG PI + EK+++PT E+ID H+
Sbjct: 254 EWCKSIFGISYPIFHGRGFFQLTFGYLPFRKPIDTVVGAPIPV-EKVENPTKEQIDELHT 312
Query: 385 LYIEELKRLYDDNKAKFNYSEKTLNIV 411
+Y ++L L+D++K K+ EK + +V
Sbjct: 313 IYCQKLTELFDEHKEKYGV-EKDVPLV 338
>CE14392 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 359
Score = 160 bits (404), Expect = 4e-39
Identities = 116/389 (29%), Positives = 176/389 (44%), Gaps = 65/389 (16%)
Query: 26 SSVVGVSKDGKPEFCA--------IDTPIERRLQTLSVAWYVECIPLMIIIMLFVWVNPL 77
SS+ G +K E C+ + P +RRL+TL+V ++ ++ I+ L+V + L
Sbjct: 6 SSISGKAKLPDKEICSSVSRILAPLLVPWKRRLETLAVMGFIFMWVILPIMDLWVPFHVL 65
Query: 78 M---WSFVIP-YTIYYFIDRTASNGNAVKRHSKWFRSLKVWFYFRDYFPISMHKSTELEP 133
W F++P Y ++++ D R W R W YF YFP+ + K+ +L
Sbjct: 66 FNTRWWFLVPLYAVWFYYD--FDTPKKASRRWNWARRHVAWKYFASYFPLRLIKTADL-- 121
Query: 134 TFTSIDSTELENDASEPGYLDSSQPVLPDKWWNPFREKDETVRPTGPRYIFGYHPHXXXX 193
P YI G HPH
Sbjct: 122 -------------------------------------------PADRNYIIGSHPHGMFS 138
Query: 194 XXXXXXXXTEACNWSKVFPGIPVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLE- 252
T A + FPGI ++TL QF P R++ + LG V++++ L
Sbjct: 139 VGGFTAMSTNATGFEDKFPGIKSHIMTLNGQFYFPFRREFGIMLGGIEVSKESLEYTLTK 198
Query: 253 --KNYSIAIVIGGASESLLTNLGSSDIILSKRKGFVKLALQTGNVSLVPVYGFGETDTYK 310
K + AIVIGGASE+L + + + L R+GF K AL+ G LVP+Y FGE D Y+
Sbjct: 199 CGKGRACAIVIGGASEALEAHPNKNTLTLINRRGFCKYALKFG-ADLVPMYNFGENDLYE 257
Query: 311 ILKLKNDSIIGRIQIWLKENYSFTVPLFFARGVFN-YDFGLLPFRHPVNVVVGNPIHIKE 369
+ S + +Q +K+ + PL R +FN Y GLLPFR PV V+G PI + +
Sbjct: 258 QYENPKGSRLREVQEKIKDMFGLCPPLLRGRSLFNQYLIGLLPFRKPVTTVMGRPIRVTQ 317
Query: 370 KIDHPTIEEIDHYHSLYIEELKRLYDDNK 398
D PT+E+ID H+ Y + L L+++ K
Sbjct: 318 -TDEPTVEQIDELHAKYCDALYNLFEEYK 345
>7304165 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 352
Score = 148 bits (373), Expect = 2e-35
Identities = 105/398 (26%), Positives = 181/398 (45%), Gaps = 71/398 (17%)
Query: 36 KPEFCAIDTPIERRLQTLSVAWYVECIPLMIIIMLFVWVNPLMW------SFVIPYTIYY 89
K E+ + P+ERRLQ L A++ + +++ + + L++ S ++ Y Y
Sbjct: 2 KIEWAPLRVPLERRLQILVTAFFTSMLLILLSVSFLLVAGSLIYGGLLVRSLMVTYLAYV 61
Query: 90 FIDRTASNGNAVKRHSKWF--RSLKVWFYFRDYFPISMHKSTELEPTFTSIDSTELENDA 147
F+ + +V + W R+ + ++RDYFP+ + K+ EL
Sbjct: 62 FVHHKKTQ--SVVDGNGWMITRTNLLHRHYRDYFPVELVKTAEL---------------- 103
Query: 148 SEPGYLDSSQPVLPDKWWNPFREKDETVRPTGPRYIFGYHPHXXXXXXXXXXXXTEACNW 207
P YI PH E W
Sbjct: 104 -----------------------------PATKNYILASFPHGILGTGIGINMGLEISKW 134
Query: 208 SKVFPGIPVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLEKNY------------ 255
++FP + L TL F +P R+ L G+ SV+++ +++L K+
Sbjct: 135 LELFPQVRPKLGTLDQHFHVPFMREVLRCWGLVSVSKEALIRMLSKSNDPKHKDNRDGFT 194
Query: 256 --SIAIVIGGASESLLTNLGSSDIILSKRKGFVKLALQTGNVSLVPVYGFGETDTYKILK 313
++AI++GGA E++ ++ G + L RKGFV++A++TG+ S+VP + FGE D + +
Sbjct: 195 SNAVAILVGGAQEAMDSHPGQYILTLKNRKGFVRMAIRTGS-SIVPSFSFGEVDIFDQVA 253
Query: 314 LKNDSIIGRIQIWLKENYSFTVPLFFARGVFNYDFGLLPFRHPVNVVVGNPIHIKEKIDH 373
+S++ R Q ++K+ + + RG FNY FG LPFR + VVG PI + K +H
Sbjct: 254 NPPNSLLRRFQDFVKKLTGVSPLIPVGRGFFNYTFGFLPFRRRIVQVVGAPIDV-VKNEH 312
Query: 374 PTIEEIDHYHSLYIEELKRLYDDNKAKFNYSEKTLNIV 411
P E +D H IE L++L+D K K+ + K+ +V
Sbjct: 313 PDSEYVDKVHGQVIESLEKLFDQYKDKYLENSKSATLV 350
>Hs18595884 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 229
Score = 139 bits (351), Expect = 6e-33
Identities = 81/223 (36%), Positives = 122/223 (54%), Gaps = 4/223 (1%)
Query: 185 GYHPHXXXXXXXXXXXXTEACNWSKVFPGIPVCLLTLVNQFQIPVYRDYLLALGITSVAR 244
G HPH TEA +SK FPGI L TL F+IP R+YL+A G+ SV++
Sbjct: 2 GVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQ 61
Query: 245 KNAMKVLEKNYS--IAIVIGGASESLLTNLGSSDIILSKRKGFVKLALQTGNVSLVPVYG 302
+L + IV+GG E+L + ++ +IL KRKGFV+ ALQ G LVP +
Sbjct: 62 PAINYLLSHGTGNLVGIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHG-AHLVPTFT 120
Query: 303 FGETDTYKILKLKNDSIIGRIQIWLKENYSFTVPLFFARGVFNYDFGLLPFRHPVNVVVG 362
FGET+ Y + DS + + Q + + F +F+ + GLLP+ P+ VVG
Sbjct: 121 FGETEVYDQVLFHKDSRMYKFQSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVG 180
Query: 363 NPIHIKEKIDHPTIEEIDHYHSLYIEELKRLYDDNKAKFNYSE 405
P+ + + I+ P+ E +D YH+LY++ L +L+D +K + SE
Sbjct: 181 EPLPLPQ-IEKPSQEMVDKYHALYMDALHKLFDQHKTHYGCSE 222
>SPCC1235.15 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 228
Score = 132 bits (333), Expect = 7e-31
Identities = 89/271 (32%), Positives = 128/271 (46%), Gaps = 56/271 (20%)
Query: 26 SSVVGVSKDGKPEFCAIDTPIERRLQTLSVAWYVECIPLMIIIMLFVWVNPLMWSFVIPY 85
+S +SKD + + LQ L+V + + L +W W F+I Y
Sbjct: 12 ASTPPISKDSRRN-------VSHWLQALAVFLHSVSLTLTASWYTVLWAFLPFWPFLIVY 64
Query: 86 TIYYFIDRTASNGNAVKRHSKWFRSLKVWFYFRDYFPISMHKSTELEPTFTSIDSTELEN 145
I+ D G R +W R+ + +F YFPI +HK+TEL+
Sbjct: 65 LIWLIYDDGFVTGK--DRQKRWLRNAPPYRWFCHYFPIRLHKTTELDS------------ 110
Query: 146 DASEPGYLDSSQPVLPDKWWNPFREKDETVRPTGPRYIFGYHPHXXXXXXXXXXXXTEAC 205
EK+ YIFGYHPH +E
Sbjct: 111 ------------------------EKN---------YIFGYHPHGIISLGAFGGFASEGA 137
Query: 206 NWSKVFPGIPVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLEK--NYSIAIVIGG 263
++SK+FPGI V +LTL + F +PVYRDYL+AL I SV++K+ + +L + S+ IVIGG
Sbjct: 138 DFSKLFPGINVSVLTLNSNFYVPVYRDYLMALNINSVSKKSCVSILSRKPGDSVLIVIGG 197
Query: 264 ASESLLTNLGSSDIILSKRKGFVKLALQTGN 294
A ESLL+ G ++++L KR GFVKLA TG+
Sbjct: 198 AQESLLSRPGQNNLVLKKRFGFVKLAFLTGS 228
>7304166 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 352
Score = 128 bits (321), Expect = 2e-29
Identities = 99/392 (25%), Positives = 173/392 (43%), Gaps = 79/392 (20%)
Query: 36 KPEFCAIDTPIERRLQTLSVAWYVECIPLM-----IIIMLFVWVNPLMW-SFVIPYTIYY 89
K E+ P+ERR QT ++A+ + ++ + ++ L+W + ++ Y +Y
Sbjct: 2 KIEWAPKGVPMERRRQTFAMAFLILSFMILSFGSYFFVAAVLFYGSLLWRTIMVIYLVYV 61
Query: 90 FID--RTAS----NGNAVKRHSKWFRSLKVWFYFRDYFPISMHKSTELEPTFTSIDSTEL 143
+ + RT S NG + R++ FR ++RDYFP+ + K+ EL P
Sbjct: 62 YANHKRTHSIMDGNGWKINRNNWLFR------HYRDYFPVQLVKTAELPPN--------- 106
Query: 144 ENDASEPGYLDSSQPVLPDKWWNPFREKDETVRPTGPRYIFGYHPHXXXXXXXXXXXXTE 203
YI PH +
Sbjct: 107 ------------------------------------KNYILASFPHGILGTGISINMGLD 130
Query: 204 ACNWSKVFPGIPVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLEKNY-------- 255
W ++FP + + TL F P+ R L + G+ SV+++ + +L K+
Sbjct: 131 ISKWLQLFPQVRPKVATLDQNFLTPIVRGLLRSWGLVSVSKEALVYLLTKSNDPKHKDNR 190
Query: 256 ------SIAIVIGGASESLLTNLGSSDIILSKRKGFVKLALQTGNVSLVPVYGFGETDTY 309
++AI++GGA E+L ++ G + L RKGFVK+A++TG+ S+VP + FGE D
Sbjct: 191 DGFTSNAVAILVGGAQEALDSHPGKYILTLKNRKGFVKMAIRTGS-SIVPTFSFGEVDIL 249
Query: 310 KILKLKNDSIIGRIQIWLKENYSFTVPLFFARGVFNYDFGLLPFRHPVNVVVGNPIHIKE 369
+ +S + R Q ++K + + RG+FNY FG LP R + VVG PI + +
Sbjct: 250 DQVANPPNSRVRRFQDFVKRITGISPLIPVGRGIFNYSFGFLPNRRRIVQVVGAPIDVVQ 309
Query: 370 KIDHPTIEEIDHYHSLYIEELKRLYDDNKAKF 401
D P +D H I++L++++ K ++
Sbjct: 310 S-DQPDAAYVDKIHKQVIDDLEKMFAKYKDQY 340
>Hs18595888 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 187
Score = 121 bits (304), Expect = 2e-27
Identities = 67/182 (36%), Positives = 103/182 (55%), Gaps = 5/182 (2%)
Query: 227 IPVYRDYLLALGITSVARKNAMKVLEKNYS---IAIVIGGASESLLTNLGSSDIILSKRK 283
+P R+Y+++ G SV+R + +L + + +VIGG +E + GSS ++L R
Sbjct: 1 MPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMVIVVIGGLAECRYSLPGSSTLVLKNRS 60
Query: 284 GFVKLALQTGNVSLVPVYGFGETDTYKILKLKNDSIIGRIQIWLKENYSFTVPLFFARGV 343
GFV++ALQ G V L+P Y FGETD Y + R Q W + F+ RG
Sbjct: 61 GFVRMALQHG-VPLIPAYAFGETDLYDQHIFTPGGFVNRFQKWFQSMVHIYPCAFYGRGF 119
Query: 344 FNYDFGLLPFRHPVNVVVGNPIHIKEKIDHPTIEEIDHYHSLYIEELKRLYDDNKAKFNY 403
+GLLP+ PV +VG P+ + KI++P+ E + YH+LYI+ L++L+D +K KF
Sbjct: 120 TKNSWGLLPYSRPVTTIVGEPLPM-PKIENPSQEIVAKYHTLYIDALRKLFDQHKTKFGI 178
Query: 404 SE 405
SE
Sbjct: 179 SE 180
>7304164 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 226
Score = 120 bits (300), Expect = 5e-27
Identities = 70/220 (31%), Positives = 123/220 (55%), Gaps = 16/220 (7%)
Query: 206 NWSKVFPGIPVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLEKNY---------- 255
NW ++P + + TL + F+ P RD L G+ SV++++ +L K+
Sbjct: 7 NWLSLYPHVRPKIATLDHHFKTPFLRDILRWWGMVSVSKESLSYLLSKSNDPMHKDNRDG 66
Query: 256 ----SIAIVIGGASESLLTNLGSSDIILSKRKGFVKLALQTGNVSLVPVYGFGETDTYKI 311
++A+++GGA E++ ++ G + L RKGFVK+A++TG+ S+VP FGE D +
Sbjct: 67 FTSNAVAVLVGGAKEAMDSHPGQYILTLKDRKGFVKMAVRTGS-SIVPSLSFGEVDIFDQ 125
Query: 312 LKLKNDSIIGRIQIWLKENYSFTVPLFFARGVFNYDFGLLPFRHPVNVVVGNPIHIKEKI 371
+ DS + R Q +K+ + L RG+FNY++G+LP R + VVG+PI + E+
Sbjct: 126 VANPPDSSLRRFQNVVKKFTGISPLLPKGRGIFNYNYGILPHRRRIVQVVGSPIDV-ERC 184
Query: 372 DHPTIEEIDHYHSLYIEELKRLYDDNKAKFNYSEKTLNIV 411
+ P E +D H I+ L R++D+ K K+ + K + ++
Sbjct: 185 ETPDPEYVDKIHGQVIDALARMFDEYKEKYTPNSKHIKLI 224
>SPCC548.01 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 155
Score = 112 bits (280), Expect = 1e-24
Identities = 64/145 (44%), Positives = 91/145 (62%), Gaps = 6/145 (4%)
Query: 261 IGGASESLLTNLGSSDIILSKRKGFVKLALQTGNVSLVPVYGFGET----DTYKILKLKN 316
IGGA ESLL+ G ++++L KR GFVKLA TG+ SLVP + FGE+ D ++ +
Sbjct: 1 IGGAQESLLSRPGQNNLVLKKRFGFVKLAFLTGS-SLVPCFAFGESGKIEDIFEQVDNNP 59
Query: 317 DSIIGRIQIWLKENYSFTVPLFFARGVFNYDFGLLPFRHPVNVVVGNPIHIKEKIDHPTI 376
+ I + Q +K+ FTVP F+ RG+ N FGL+P+R P+N+VVG PI + +K HPT
Sbjct: 60 RTRIYKFQEIVKKIAGFTVPFFYGRGLLNKTFGLMPWRKPINIVVGEPIDVPKK-SHPTN 118
Query: 377 EEIDHYHSLYIEELKRLYDDNKAKF 401
+EI H YI L+ L++ K F
Sbjct: 119 QEIYEVHEEYIRRLEGLWNKYKDVF 143
>Hs13376662 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 284
Score = 109 bits (272), Expect = 9e-24
Identities = 75/266 (28%), Positives = 116/266 (43%), Gaps = 61/266 (22%)
Query: 38 EFCAIDTPIERRLQTLSVAWYV-------ECIPLMIIIMLFVWVNPLMWSFVIPYTIYYF 90
EF + P ERRLQTL+V +V E + I +LF W + Y +++
Sbjct: 3 EFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIALLFT----RFWLLTVLYAAWWY 58
Query: 91 IDRTASNGNAVKRHSKWFRSLKVWFYFRDYFPISMHKSTELEPTFTSIDSTELENDASEP 150
+DR RH + R +W Y +DYFPIS+ K+ EL+P+
Sbjct: 59 LDRDKPRQGG--RHIQAIRCWTIWKYMKDYFPISLVKTAELDPS---------------- 100
Query: 151 GYLDSSQPVLPDKWWNPFREKDETVRPTGPRYIFGYHPHXXXXXXXXXXXXTEACNWSKV 210
YI G+HPH TE+ +S +
Sbjct: 101 -----------------------------RNYIAGFHPHGVLAVGAFANLCTESTGFSSI 131
Query: 211 FPGIPVCLLTLVNQFQIPVYRDYLLALGITSVARKNAMKVLEKNYS---IAIVIGGASES 267
FPGI L+ F+ P +RDY+++ G+ + +++A +L + + I++GGA E+
Sbjct: 132 FPGIRPHLMMPTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNLLGIIVGGAQEA 191
Query: 268 LLTNLGSSDIILSKRKGFVKLALQTG 293
L GS ++L RKGFV+LAL G
Sbjct: 192 LDARPGSFTLLLRNRKGFVRLALTHG 217
>Hs22058366 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 183
Score = 105 bits (261), Expect = 2e-22
Identities = 60/171 (35%), Positives = 93/171 (54%), Gaps = 6/171 (3%)
Query: 239 ITSVARKNAMKVLEKNYSIAIVIGGASESLLTNLGSSDIILSKRKGFVKLALQTGNVSLV 298
++S A K + ++ IV+GGA+E+LL G+S + L +RKGFVK+ALQTG LV
Sbjct: 8 VSSSALKYLLTQKGSGNAVVIVVGGAAEALLCRPGASTLFLKQRKGFVKMALQTG-AYLV 66
Query: 299 PVYGFGETDTYKILKLKNDSIIGRIQIWLKENYSFTVPL----FFARGVFNYDFGLLPFR 354
P Y FGE + + + + Q ++ + + L F RG +G LPF
Sbjct: 67 PSYSFGENEVFNQETFPEGTWLRLFQKTFQDTFKKILGLNFCTFHGRGFTRGSWGFLPFN 126
Query: 355 HPVNVVVGNPIHIKEKIDHPTIEEIDHYHSLYIEELKRLYDDNKAKFNYSE 405
P+ VVG P+ I +I P + +D YH+LYI L++L+D +K ++ E
Sbjct: 127 RPITTVVGEPLPI-PRIKRPNQKTVDKYHALYISALRKLFDQHKVEYGLPE 176
>At3g51520 [I] KOG0831 Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Length = 327
Score = 99.0 bits (245), Expect = 1e-20
Identities = 73/235 (31%), Positives = 113/235 (48%), Gaps = 30/235 (12%)
Query: 182 YIFGYHPHXXXXXXXXXXXXTEACNWSKVFPGIPVCLLTLVNQFQIPVYRDYLLALGITS 241
Y+FGY PH C+ + P + +L F P R LG+T+
Sbjct: 103 YVFGYEPHSVLPIGVVAL-----CDLTGFMPIPNIKVLASSAIFYTPFLRHIWTWLGLTA 157
Query: 242 VARKNAMKVLEKNYSIAIVIGGASES-------------LLTNLGSSDIILSKRKGFVKL 288
+RKN +L+ YS +V GG E+ + L ++ LS+R+GFV++
Sbjct: 158 ASRKNFTSLLDSGYSCVLVPGGVQETFHMQHDAESDDFLIELYLTLQNVFLSRRRGFVRI 217
Query: 289 ALQTGNVSLVPVYGFGETDTYKILKLKNDSIIGRIQIWLKENYSFTVPLFFARGVFNYDF 348
A++ G+ LVPV+ FG+ YK K D + + L FT F+ GVF
Sbjct: 218 AMEQGS-PLVPVFCFGQARVYKWWKPDCD-----LYLKLSRAIRFTPICFW--GVFG--- 266
Query: 349 GLLPFRHPVNVVVGNPIHIKEKIDHPTIEEIDHYHSLYIEELKRLYDDNKAKFNY 403
LP R P++VVVG PI + + + PT EEI +H Y+E L+ L++ +K++ Y
Sbjct: 267 SPLPCRQPMHVVVGKPIEVTKTL-KPTDEEIAKFHGQYVEALRDLFERHKSRVGY 320
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.139 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,456,462
Number of Sequences: 60738
Number of extensions: 1111407
Number of successful extensions: 2687
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2610
Number of HSP's gapped (non-prelim): 28
length of query: 412
length of database: 30,389,216
effective HSP length: 109
effective length of query: 303
effective length of database: 23,768,774
effective search space: 7201938522
effective search space used: 7201938522
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)