ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2925 good B KOG2747 Chromatin structure and dynamics Histone acetyltransferase (MYST family)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2925 1034343 1033027 -439
(439 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR244w [B] KOG2747 Histone acetyltransferase (MYST family) 694 0.0
SPAC637.12c [B] KOG2747 Histone acetyltransferase (MYST family) 472 e-133
CE21225 [B] KOG2747 Histone acetyltransferase (MYST family) 341 1e-93
7290469 [B] KOG2747 Histone acetyltransferase (MYST family) 333 3e-91
At5g09740 [B] KOG2747 Histone acetyltransferase (MYST family) 330 2e-90
At5g64610 [B] KOG2747 Histone acetyltransferase (MYST family) 325 6e-89
Hs5454128 [B] KOG2747 Histone acetyltransferase (MYST family) 320 2e-87
Hs5901962 [B] KOG2747 Histone acetyltransferase (MYST family) 296 3e-80
Hs14149875 [B] KOG2747 Histone acetyltransferase (MYST family) 296 4e-80
7290646 [B] KOG2747 Histone acetyltransferase (MYST family) 288 1e-77
ECU10g0660 [B] KOG2747 Histone acetyltransferase (MYST family) 281 2e-75
Hs5803098 [B] KOG2747 Histone acetyltransferase (MYST family) 263 3e-70
Hs6912512 [B] KOG2747 Histone acetyltransferase (MYST family) 258 9e-69
SPAC17G8.13c [B] KOG2747 Histone acetyltransferase (MYST family) 250 3e-66
CE23850 [B] KOG2747 Histone acetyltransferase (MYST family) 245 1e-64
7291743 [B] KOG2747 Histone acetyltransferase (MYST family) 245 1e-64
YBL052c [B] KOG2747 Histone acetyltransferase (MYST family) 238 1e-62
Hs20549811 [B] KOG2747 Histone acetyltransferase (MYST family) 234 2e-61
7301677 [B] KOG2747 Histone acetyltransferase (MYST family) 209 5e-54
CE06262 [B] KOG2747 Histone acetyltransferase (MYST family) 205 1e-52
7297249 [B] KOG2747 Histone acetyltransferase (MYST family) 181 2e-45
CE27818 [B] KOG2747 Histone acetyltransferase (MYST family) 180 3e-45
ECU09g1310 [B] KOG2747 Histone acetyltransferase (MYST family) 140 5e-33
YMR127c [B] KOG2747 Histone acetyltransferase (MYST family) 134 2e-31
>YOR244w [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 445
Score = 694 bits (1790), Expect = 0.0
Identities = 329/445 (73%), Positives = 376/445 (83%), Gaps = 6/445 (1%)
Query: 1 MSHGEEKEPGIPQKVDSIDEIFVGCKSWVLKDGQDRLAEILSINSRRDPPKFYVHYEDFN 60
MSH ++EPGI +K++S+D+I + C+ WV K+ ++RLAEILSIN+R+ PPKFYVHY ++N
Sbjct: 1 MSHDGKEEPGIAKKINSVDDIIIKCQCWVQKNDEERLAEILSINTRKAPPKFYVHYVNYN 60
Query: 61 KRLDEWITADRLQIDKEVIFPRPXXXXXXXXXXXXXXXXXXSATPQAA------SATPDG 114
KRLDEWIT DR+ +DKEV++P+ S TPQ + + +
Sbjct: 61 KRLDEWITTDRINLDKEVLYPKLKATDEDNKKQKKKKATNTSETPQDSLQDGVDGFSREN 120
Query: 115 GDVMDLDNLNVQGIPNEDISREDEIKKLRTSGSMTQNQNEVARVRNLNKVIMGKYEIEPW 174
DVMDLDNLNVQGI +E+IS EDEIKKLRTSGSMTQN +EVARVRNLN++IMGKYEIEPW
Sbjct: 121 TDVMDLDNLNVQGIKDENISHEDEIKKLRTSGSMTQNPHEVARVRNLNRIIMGKYEIEPW 180
Query: 175 YFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEID 234
YFSPYPIELTDED +YIDDF+LQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEID
Sbjct: 181 YFSPYPIELTDEDFIYIDDFTLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEID 240
Query: 235 GRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAY 294
GRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHH+VGYFSKEKESAD Y
Sbjct: 241 GRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHLVGYFSKEKESADGY 300
Query: 295 NVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKL 354
NVACILTLPQYQRMGYG+LLIEFSYELSKKE KVGSPEKPLSDLGLLSYRAYW+DTLI L
Sbjct: 301 NVACILTLPQYQRMGYGKLLIEFSYELSKKENKVGSPEKPLSDLGLLSYRAYWSDTLITL 360
Query: 355 LVEHGQEITIDEVSSISSMTTTDILHTAKALEILRFYRGQHVLYLNSDVMXXXXXXXXXX 414
LVEH +EITIDE+SS++SMTTTDILHTAK L ILR+Y+GQH+++LN D++
Sbjct: 361 LVEHQKEITIDEISSMTSMTTTDILHTAKTLNILRYYKGQHIIFLNEDILDRYNRLKAKK 420
Query: 415 XXSIDPQKLIWTPPVFTASQLRFAW 439
+IDP +LIW PPVFTASQLRFAW
Sbjct: 421 RRTIDPNRLIWKPPVFTASQLRFAW 445
>SPAC637.12c [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 463
Score = 472 bits (1215), Expect = e-133
Identities = 236/463 (50%), Positives = 305/463 (64%), Gaps = 24/463 (5%)
Query: 1 MSHGEEKEPGIPQKVDSIDEIFVGCKSWVLKDGQDRLAEILSINSRRDPPKFYVHYEDFN 60
MS+ + E I K +I K + KDG+ R AEIL I R +YVHY D+N
Sbjct: 1 MSNDVDDESKIETKSYEAKDIVYKSKVFAFKDGEYRKAEILMIQKRTRGVVYYVHYNDYN 60
Query: 61 KRLDEWITADRLQIDKEVIFPRPXX--------------XXXXXXXXXXXXXXXXSATPQ 106
KRLDEWIT D + + K + +P P +TP
Sbjct: 61 KRLDEWITIDNIDLSKGIEYPPPEKPKKAHGKGKSSKRPKAVDRRRSITAPSKTEPSTPS 120
Query: 107 AASATPD--GGDVMDLDNLNVQGIP-------NEDISREDEIKKLRTSGSMTQNQNEVAR 157
P G+ N + +P E +S+E E+++LR SGSM QN +E+AR
Sbjct: 121 TEKPEPSTPSGESDHGSNAGNESLPLLEEDHKPESLSKEQEVERLRFSGSMVQNPHEIAR 180
Query: 158 VRNLNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHP 217
+RN+NK+ +G +EIEPWYFSPYP E ++ D+VYI F Y+GS++Q++R+R+KCTL+HP
Sbjct: 181 IRNINKICIGDHEIEPWYFSPYPKEFSEVDIVYICSFCFCYYGSERQFQRHREKCTLQHP 240
Query: 218 PGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELG 277
PGNEIYRDDY+SFFEIDGRKQRTWCRN+CLLSKLFLDHK LYYDVDPFLFYCM RRDE G
Sbjct: 241 PGNEIYRDDYISFFEIDGRKQRTWCRNICLLSKLFLDHKMLYYDVDPFLFYCMCRRDEYG 300
Query: 278 HHIVGYFSKEKESADAYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSD 337
H+VGYFSKEKES++ YN+ACILTLPQYQR GYG+LLI+FSYEL+K+E K GSPEKPLSD
Sbjct: 301 CHLVGYFSKEKESSENYNLACILTLPQYQRHGYGKLLIQFSYELTKREHKHGSPEKPLSD 360
Query: 338 LGLLSYRAYWADTLIKLLVEHGQEITIDEVSSISSMTTTDILHTAKALEILRFYRGQHVL 397
LGL+SYRAYWA+ +I L++ E TIDE+++ +SMTT D+LHT +AL +L++Y+GQ ++
Sbjct: 361 LGLISYRAYWAEQIINLVLGMRTETTIDELANKTSMTTNDVLHTLQALNMLKYYKGQFII 420
Query: 398 YLNSDVMXXXXXXXXXXXXSIDPQKLI-WTPPVFTASQLRFAW 439
++ + I+ L W PPVF SQLRF W
Sbjct: 421 CISDGIEQQYERLKNKKRRRINGDLLADWQPPVFHPSQLRFGW 463
>CE21225 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 458
Score = 341 bits (874), Expect = 1e-93
Identities = 184/440 (41%), Positives = 265/440 (59%), Gaps = 20/440 (4%)
Query: 2 SHGEEKEPGIPQKVDSIDEIFVGCKSWVLKDGQD--RLAEILS-INSRRDPPKFYVHYED 58
+HG K+ IP +++ GC+ V+ Q+ R AE++S + KFYVHY D
Sbjct: 13 NHGISKK--IPTDPRQYEKVTEGCRLLVMMASQEEERWAEVISRCRAANGSIKFYVHYID 70
Query: 59 FNKRLDEWITADRLQIDKEVIFPRPXXXXXXXXXXXXXXXXXXSATPQAASATPDGGDVM 118
N+RLDEW+ +DRL + + + P ++
Sbjct: 71 CNRRLDEWVQSDRLNLASCELPKKGGKKGAHLREENRDSNENEGKKSGRKRKIP----LL 126
Query: 119 DLDNLNVQGI-PNEDISR--EDEIKKLRTSGSMT-QNQNEVARVRNLNKVIMGKYEIEPW 174
+D+L + + P + IS LR S SM +++ + R+RN+ + +G+ I+PW
Sbjct: 127 PMDDLKAESVDPLQAISTMTSGSTPSLRGSMSMVGHSEDAMTRIRNVECIELGRSRIQPW 186
Query: 175 YFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEID 234
YF+PYP +LT D +YI +F L+Y SK +R+ +KC + HPPGN+IY D +SFFEID
Sbjct: 187 YFAPYPQQLTSLDCIYICEFCLKYLKSKTCLKRHMEKCAMCHPPGNQIYSHDKLSFFEID 246
Query: 235 GRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAY 294
GRK +++ +NLCLL+KLFLDHKTLYYD DPFLFY +T DE GHHIVGYFSKEKESA+ Y
Sbjct: 247 GRKNKSYAQNLCLLAKLFLDHKTLYYDTDPFLFYVLTEEDEKGHHIVGYFSKEKESAEEY 306
Query: 295 NVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKL 354
NVACIL LP +Q+ GYG LLIEFSYELSK E K GSPEKPLSDLGLLSYR+YW+ ++K
Sbjct: 307 NVACILVLPPFQKKGYGSLLIEFSYELSKIEQKTGSPEKPLSDLGLLSYRSYWSMAIMKE 366
Query: 355 LV-----EHGQEITIDEVSSISSMTTTDILHTAKALEILRFYRGQHVLYLNSD--VMXXX 407
L G++IT+ ++S +S+ D++ T + L++ ++Y+G +++ ++ + +
Sbjct: 367 LFAFKRRHPGEDITVQDISQSTSIKREDVVSTLQQLDLYKYYKGSYIIVISDEKRQVYEK 426
Query: 408 XXXXXXXXXSIDPQKLIWTP 427
I+P L W P
Sbjct: 427 RIEAAKKKTRINPAALQWRP 446
>7290469 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 510
Score = 333 bits (854), Expect = 3e-91
Identities = 169/334 (50%), Positives = 223/334 (66%), Gaps = 14/334 (4%)
Query: 104 TPQAASATPDG--GDVMDLDNLNVQGIPNEDISREDEIKKLRTSGSMTQNQNEVA-RVRN 160
TPQ +ATP GD + N G D S++ + R SGSM +Q++V R++N
Sbjct: 172 TPQTPTATPVHVTGDGLISGAANDDG----DGSQDGKTPTPRQSGSMVTHQDDVVTRMKN 227
Query: 161 LNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGN 220
+ + +G++ I+PWYFSPYP EL +YI +F L+Y S+K ER+ KC LRHPPGN
Sbjct: 228 VEMIELGRHRIKPWYFSPYPQELCQMPCIYICEFCLKYRKSRKCLERHLSKCNLRHPPGN 287
Query: 221 EIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHI 280
EIYR +SFFEIDGRK + + +NLCLL+KLFLDHKTLYYD DPFLFY MT D G HI
Sbjct: 288 EIYRKHTISFFEIDGRKNKVYAQNLCLLAKLFLDHKTLYYDTDPFLFYVMTEFDSRGFHI 347
Query: 281 VGYFSKEKESADAYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGL 340
VGYFSKEKES + YNVACILT+P YQR GYG+LLIEFSYELSK EGK GSPEKPLSDLGL
Sbjct: 348 VGYFSKEKESTEDYNVACILTMPPYQRKGYGKLLIEFSYELSKFEGKTGSPEKPLSDLGL 407
Query: 341 LSYRAYWADTLIKLLVEHGQE-------ITIDEVSSISSMTTTDILHTAKALEILRFYRG 393
LSYR+YWA T++++ + ITI+++ +S+ D++ T + L ++ +Y+G
Sbjct: 408 LSYRSYWAQTILEIFISQNPSTDGEKPTITINDICECTSIKKEDVISTLQNLNLINYYKG 467
Query: 394 QHVLYLNSDVMXXXXXXXXXXXXSIDPQKLIWTP 427
Q+++ +N ++ ID + L WTP
Sbjct: 468 QYIVCINRVIIEQHRRAMDKRKIRIDSKCLHWTP 501
>At5g09740 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 445
Score = 330 bits (847), Expect = 2e-90
Identities = 163/384 (42%), Positives = 231/384 (59%), Gaps = 31/384 (8%)
Query: 44 NSRRDPPKFYVHYEDFNKRLDEWITADRLQIDKEVIFPRPXXXXXXXXXXXXXXXXXXSA 103
N ++ ++YVHY +FN+RLDEW D+L +D
Sbjct: 88 NGGQNDYEYYVHYTEFNRRLDEWTQLDQLDLDS------------------VECAVDEKV 129
Query: 104 TPQAASATPDGGDVMDLDNLNVQGIPNEDISREDEIKKLRTSGSMTQNQNEVARVRNLNK 163
+ S +D +++G D + + E +V+N++
Sbjct: 130 EDKVTSLKMTRHQKRKIDETHIEGHEELD-------------AASLREHEEFTKVKNIST 176
Query: 164 VIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIY 223
+ +GKYEIE WYFSP+P E D ++ +F L + K+Q +R+ +KC L+HPPG+EIY
Sbjct: 177 IELGKYEIETWYFSPFPPEYNDCVKLFFCEFCLNFMKRKEQLQRHMRKCDLKHPPGDEIY 236
Query: 224 RDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGY 283
R +S FE+DG+K + + +NLC L+KLFLDHKTLYYDVD FLFY + D+ G H+VGY
Sbjct: 237 RSGTLSMFEVDGKKNKVYAQNLCYLAKLFLDHKTLYYDVDLFLFYVLCECDDRGCHMVGY 296
Query: 284 FSKEKESADAYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSY 343
FSKEK S +AYN+ACILTLP YQR GYG+ LI FSYELSKKEGKVG+PE+PLSDLGLLSY
Sbjct: 297 FSKEKHSEEAYNLACILTLPSYQRKGYGKFLIAFSYELSKKEGKVGTPERPLSDLGLLSY 356
Query: 344 RAYWADTLIKLLVEHGQEITIDEVSSISSMTTTDILHTAKALEILRFYRGQHVLYLNSDV 403
R YW L+++L +H I+I E+S ++++ DIL T ++LE++++ +GQHV+ + V
Sbjct: 357 RGYWTRVLLEILKKHKGNISIKELSDVTAIKAEDILSTLQSLELIQYRKGQHVICADPKV 416
Query: 404 MXXXXXXXXXXXXSIDPQKLIWTP 427
+ +D KLIWTP
Sbjct: 417 LDRHLKAAGRGGLDVDASKLIWTP 440
>At5g64610 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 445
Score = 325 bits (834), Expect = 6e-89
Identities = 162/384 (42%), Positives = 229/384 (59%), Gaps = 31/384 (8%)
Query: 44 NSRRDPPKFYVHYEDFNKRLDEWITADRLQIDKEVIFPRPXXXXXXXXXXXXXXXXXXSA 103
N + ++YVHY +FN+RLDEWI ++L +D
Sbjct: 88 NGGHNDYEYYVHYTEFNRRLDEWIKLEQLDLDS------------------VECALDEKV 129
Query: 104 TPQAASATPDGGDVMDLDNLNVQGIPNEDISREDEIKKLRTSGSMTQNQNEVARVRNLNK 163
+ S +D +V+G D + + E +V+N+
Sbjct: 130 EDKVTSLKMTRHQKRKIDETHVEGHEELD-------------AASLREHEEFTKVKNIAT 176
Query: 164 VIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIY 223
+ +GKYEIE WYFSP+P E D ++ +F L + K+Q +R+ +KC L+HPPG+EIY
Sbjct: 177 IELGKYEIETWYFSPFPPEYNDCVKLFFCEFCLSFMKRKEQLQRHMRKCDLKHPPGDEIY 236
Query: 224 RDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGY 283
R +S FE+DG+K + + +NLC L+KLFLDHKTLYYDVD FLFY + D+ G H+VGY
Sbjct: 237 RSSTLSMFEVDGKKNKVYAQNLCYLAKLFLDHKTLYYDVDLFLFYILCECDDRGCHMVGY 296
Query: 284 FSKEKESADAYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSY 343
FSKEK S +AYN+ACILTLP YQR GYG+ LI FSYELSKKEGKVG+PE+PLSDLGL+SY
Sbjct: 297 FSKEKHSEEAYNLACILTLPPYQRKGYGKFLIAFSYELSKKEGKVGTPERPLSDLGLVSY 356
Query: 344 RAYWADTLIKLLVEHGQEITIDEVSSISSMTTTDILHTAKALEILRFYRGQHVLYLNSDV 403
R YW L+ +L +H I+I E+S ++++ DIL T ++LE++++ +GQHV+ + V
Sbjct: 357 RGYWTRILLDILKKHKGNISIKELSDMTAIKAEDILSTLQSLELIQYRKGQHVICADPKV 416
Query: 404 MXXXXXXXXXXXXSIDPQKLIWTP 427
+ +D K+IWTP
Sbjct: 417 LDRHLKAAGRGGLDVDVSKMIWTP 440
>Hs5454128 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 513
Score = 320 bits (821), Expect = 2e-87
Identities = 157/294 (53%), Positives = 213/294 (72%), Gaps = 9/294 (3%)
Query: 143 RTSGSMTQNQNE---VARVRNLNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYF 199
R +GS+ +++ V R++N+ + +G++ ++PWYFSPYP ELT V+Y+ +F L+Y
Sbjct: 211 RMTGSLVSDRSHDDIVTRMKNIECIELGRHRLKPWYFSPYPQELTTLPVLYLCEFCLKYG 270
Query: 200 GSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLY 259
S K +R+ KC LRHPPGNEIYR +SFFEIDGRK +++ +NLCLL+K FLDHKTLY
Sbjct: 271 RSLKCLQRHLTKCDLRHPPGNEIYRKGTISFFEIDGRKNKSYSQNLCLLAKCFLDHKTLY 330
Query: 260 YDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQYQRMGYGRLLIEFSY 319
YD DPFLFY MT D G HIVGYFSKEKES + YNVACILTLP YQR GY +LLIEFSY
Sbjct: 331 YDTDPFLFYVMTEYDCKGFHIVGYFSKEKESTEDYNVACILTLPPYQRRGYRKLLIEFSY 390
Query: 320 ELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKLLV----EHGQ--EITIDEVSSISSM 373
ELSK EGK G+PEKPLSDLGLLSYR+YW+ T++++L+ E G+ +ITI+E+S I+S+
Sbjct: 391 ELSKVEGKTGTPEKPLSDLGLLSYRSYWSQTILEILMGLKSESGERPQITINEISEITSI 450
Query: 374 TTTDILHTAKALEILRFYRGQHVLYLNSDVMXXXXXXXXXXXXSIDPQKLIWTP 427
D++ T + L ++ +Y+GQ++L L+ D++ ID + L +TP
Sbjct: 451 KKEDVISTLQYLNLINYYKGQYILTLSEDIVDGHERAMLKRLLRIDSKCLHFTP 504
Score = 63.2 bits (152), Expect = 8e-10
Identities = 34/70 (48%), Positives = 44/70 (62%), Gaps = 6/70 (8%)
Query: 18 IDEIFVGCKSWVLKDGQDR-----LAEILSINSRRDPPKFYVHYEDFNKRLDEWITADRL 72
+ EI GC+ VL+ QD LAEILS+ FYVHY DFNKRLDEW+T +RL
Sbjct: 4 VGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTHERL 63
Query: 73 QIDKEVIFPR 82
+ K++ FP+
Sbjct: 64 DL-KKIQFPK 72
>Hs5901962 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 611
Score = 296 bits (759), Expect = 3e-80
Identities = 141/296 (47%), Positives = 201/296 (67%), Gaps = 10/296 (3%)
Query: 137 DEIKKLRTSGSMTQNQNEVARVRNLNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSL 196
++++KLR G +T+ N + + G+YE++ WY SPYP E +Y+ +F L
Sbjct: 319 EDLEKLRLQGQITEGSNMI------KTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCL 372
Query: 197 QYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHK 256
+Y S+ R+ KC +HPPG+EIYR +S FE+DG+K + +C+NLCLL+KLFLDHK
Sbjct: 373 KYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHK 432
Query: 257 TLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQYQRMGYGRLLIE 316
TLYYDV+PFLFY MT D G H++GYFSKEK S YNV+CILT+PQY R GYG++LI+
Sbjct: 433 TLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLID 492
Query: 317 FSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKLLVE-HGQEITIDEVSSISSMTT 375
FSY LSK E KVGSPE+PLSDLGL+SYR+YW + L++ L G+EI+I E+S +++
Sbjct: 493 FSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNP 552
Query: 376 TDILHTAKALEILRFYRGQHVLYLNSDVMXXXXXXXXXXXXS---IDPQKLIWTPP 428
DI+ T +AL++L++++G+H++ D++ S +DP L WTPP
Sbjct: 553 VDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPP 608
>Hs14149875 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 458
Score = 296 bits (758), Expect = 4e-80
Identities = 155/403 (38%), Positives = 234/403 (57%), Gaps = 39/403 (9%)
Query: 38 AEILS--INSRRDPPKFYVHYEDFNKRLDEWITADRLQIDKEVIFPRPXXXXXXXXXXXX 95
AE++ +N + +FYVHY FN+RLDEW+ +RL + K V
Sbjct: 73 AEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTV----------------- 115
Query: 96 XXXXXXSATPQAASATPDGGDVMDLDNLNVQGIPNEDISREDEIKKLR--------TSGS 147
+ A + +L + I + DEI ++ T+ +
Sbjct: 116 ----------KDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAA 165
Query: 148 MTQNQNEVARVRNLNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYER 207
+ + + +V+ ++K+ +G YEI+ WYFSP+P + + +++ ++ L+Y +K Y
Sbjct: 166 LEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRF 225
Query: 208 YRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLF 267
+ +C R PPG EIYR +S E+DG+ + +C+NLCLL+KLFLDHKTLY+DV+PF+F
Sbjct: 226 HLGQCQWRQPPGKEIYRKSNISVHEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVF 285
Query: 268 YCMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGK 327
Y +T D G HIVGYFSKEKES D NVACILTLP YQR GYG+ LI FSYELSK E
Sbjct: 286 YILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLEST 345
Query: 328 VGSPEKPLSDLGLLSYRAYWADTLIKLLVEHGQEITIDEVSSISSMTTTDILHTAKALEI 387
VGSPEKPLSDLG LSYR+YW+ L++ L + ++I ++S ++S+T DI+ T ++L +
Sbjct: 346 VGSPEKPLSDLGKLSYRSYWSWVLLENLRDFRGTLSIKDLSQMTSITQNDIISTLQSLNM 405
Query: 388 LRFYRGQHVLYLNSDVMXXXXXXXXXXX--XSIDPQKLIWTPP 428
+++++GQHV+ + ++ ++D L W PP
Sbjct: 406 VKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAPP 448
>7290646 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 827
Score = 288 bits (737), Expect = 1e-77
Identities = 152/431 (35%), Positives = 243/431 (56%), Gaps = 29/431 (6%)
Query: 31 KDGQDRLAEILSINSRRD---PPKFYVHYEDFNKRLDEWITADRLQIDKE-----VIFPR 82
+DG ++L + + P ++YVHY N+RLD W+ R+ + + + P
Sbjct: 388 EDGTVHRGQVLQSRTTENAAAPDEYYVHYVGLNRRLDGWVGRHRISDNADDLGGITVLPA 447
Query: 83 PXXXXXXXXXXXXXXXXXXSATPQAASATPDGGDVMDLD---------NLNVQGIPNEDI 133
P +A A+S D + + + +
Sbjct: 448 PPLAPDQPSTSREMLAQQAAAAAAASSERQKRAANKDYYLSYCENSRYDYSDRKMTRYQK 507
Query: 134 SREDEIKKLR--------TSGSMTQNQNEVARVRNLNKVIMGKYEIEPWYFSPYPIELTD 185
R DEI ++ T ++ + + +++ ++K+ G YEI+ WYFSP+P E
Sbjct: 508 RRYDEINHVQKSHAELTATQAALEKEHESITKIKYIDKLQFGNYEIDTWYFSPFPEEYGK 567
Query: 186 EDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNL 245
+Y+ ++ L+Y + Y + +C R PPG EIYR +S +E++G+++ +C+ L
Sbjct: 568 ARTLYVCEYCLKYMRFRSSYAYHLHECDRRRPPGREIYRKGNISIYEVNGKEESLYCQLL 627
Query: 246 CLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQY 305
CL++KLFLDHK LY+D+DPFLFY + D+ G HIVGYFSKEK+S + YNVACIL LP +
Sbjct: 628 CLMAKLFLDHKVLYFDMDPFLFYILCETDKEGSHIVGYFSKEKKSLENYNVACILVLPPH 687
Query: 306 QRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKLLVEH--GQEIT 363
QR G+G+LLI FSYELS+KEG +GSPEKPLSDLG LSYR+YWA TL++L+ ++IT
Sbjct: 688 QRKGFGKLLIAFSYELSRKEGVIGSPEKPLSDLGRLSYRSYWAYTLLELMKTRCAPEQIT 747
Query: 364 IDEVSSISSMTTTDILHTAKALEILRFYRGQHVLYLNSDVMXXXXX--XXXXXXXSIDPQ 421
I E+S +S +T DI++T ++++++++++GQ+V+ + S + +ID
Sbjct: 748 IKELSEMSGITHDDIIYTLQSMKMIKYWKGQNVICVTSKTIQDHLQLPQFKQPKLTIDTD 807
Query: 422 KLIWTPPVFTA 432
L+W+P A
Sbjct: 808 YLVWSPQTAAA 818
>ECU10g0660 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 377
Score = 281 bits (718), Expect = 2e-75
Identities = 152/389 (39%), Positives = 221/389 (56%), Gaps = 39/389 (10%)
Query: 18 IDEIFVGCKSWVLK--DGQDRL--AEILSINSRRDPPKFYVHYEDFNKRLDEWITADRLQ 73
++++ VG K V K DG + + AEIL + + +FYVHY + N+RLDEWI +
Sbjct: 3 LEDVCVGFKVPVRKAVDGGEEVFKAEILGKRAGKSGLEFYVHYVELNRRLDEWIDGSMID 62
Query: 74 IDKEVIFPRPXXXXXXXXXXXXXXXXXXSATPQAASATPDGGDVMDLDNLNVQGIPNEDI 133
+ P + + ++
Sbjct: 63 LGDPAQIEIPKKKKTEKTKSEKS-----------------------------ERVSEKEG 93
Query: 134 SREDEIKKLRTSGSMTQNQNEVARVRNLNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDD 193
+ DE KL Q+E +++N+ K+++ Y ++ WYFSPYP + + D+VYI +
Sbjct: 94 EQRDEEPKLERPP-----QDEEFKMKNVKKIMLRNYLVDAWYFSPYPKAVAESDIVYICE 148
Query: 194 FSLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFL 253
F L YF + + ++C LRHPPG EIYRD +SFFE DG Q+ +CRNL LLSKLFL
Sbjct: 149 FCLYYFSAVDSLVLHARQCKLRHPPGREIYRDGVLSFFECDGHIQKNYCRNLSLLSKLFL 208
Query: 254 DHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQYQRMGYGRL 313
DHK+LYYD+D F+FY + R ++ G+ IVGYFSKEK S YN+ACILTLP QR GYG++
Sbjct: 209 DHKSLYYDIDVFMFYVLCRLEDNGYQIVGYFSKEKMSEQGYNLACILTLPFEQRKGYGKI 268
Query: 314 LIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKLLVEHGQEITIDEVSSISSM 373
LI+FSY LS++E V PEKPLSDLGLLSYRAYW + +++ L +H + +I E+S + +
Sbjct: 269 LIDFSYLLSRRENVVSGPEKPLSDLGLLSYRAYWMEVIVEYLSKH-DKASISEISRETYI 327
Query: 374 TTTDILHTAKALEILRFYRGQHVLYLNSD 402
+ D++ T A ++LR + + D
Sbjct: 328 SEDDVIGTLCAYKMLRMEGNEFIFTYAED 356
>Hs5803098 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 2004
Score = 263 bits (673), Expect = 3e-70
Identities = 132/280 (47%), Positives = 180/280 (64%), Gaps = 3/280 (1%)
Query: 157 RVRNLNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRH 216
+VR + + GKYEI WY SPYP E + +Y+ +F L+Y S+ +++ KKC H
Sbjct: 505 QVRCPSVIEFGKYEIHTWYSSPYPQEYSRLPKLYLCEFCLKYMKSRTILQQHMKKCGWFH 564
Query: 217 PPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDEL 276
PP NEIYR + +S FE+DG +C+NLCLL+KLFLDHKTLYYDV+PFLFY +T+ D
Sbjct: 565 PPANEIYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVK 624
Query: 277 GHHIVGYFSKEKESADAYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLS 336
G H+VGYFSKEK YNV+CI+ LPQYQR GYGR LI+FSY LSK+EG+ GSPEKPLS
Sbjct: 625 GCHLVGYFSKEKHCQQKYNVSCIMILPQYQRKGYGRFLIDFSYLLSKREGQAGSPEKPLS 684
Query: 337 DLGLLSYRAYWADTLIKLLV-EHGQEITIDEVSSISSMTTTDILHTAKALEILRFYRGQH 395
DLG LSY AYW +++ L ++ ++I+I ++S ++ + DI T L +L F Q
Sbjct: 685 DLGRLSYMAYWKSVILECLYHQNDKQISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQF 744
Query: 396 VLYLNSDVMXXXXXXXXXXX--XSIDPQKLIWTPPVFTAS 433
V+ ++ +DP+ L WTP + + S
Sbjct: 745 VIIRREKLIQDHMAKLQLNLRPVDVDPECLRWTPVIVSNS 784
>Hs6912512 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 2073
Score = 258 bits (660), Expect = 9e-69
Identities = 140/350 (40%), Positives = 198/350 (56%), Gaps = 26/350 (7%)
Query: 104 TPQAASATPDGGDVMD------------------LDNLNVQGIPNEDISREDEIKKLRTS 145
TPQ + +P G + D ++ +V I N+D+ E+++ + +
Sbjct: 640 TPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQA 699
Query: 146 GSMTQNQNEVARV-----RNLNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFG 200
++ + E R + + GKYEI+ WY SPYP E +Y+ +F L+Y
Sbjct: 700 QELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMK 759
Query: 201 SKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYY 260
SK R+ KKC HPP NEIYR +S FE+DG + +C+NLCLL+KLFLDHKTLYY
Sbjct: 760 SKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYY 819
Query: 261 DVDPFLFYCMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQYQRMGYGRLLIEFSYE 320
DV+PFLFY +T+ DE G H+VGY SKEK YNV+CI+ +PQ+QR G+GR LI+FSY
Sbjct: 820 DVEPFLFYVLTKNDEKGCHLVGYLSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYL 879
Query: 321 LSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKLLVEHGQ-EITIDEVSSISSMTTTDIL 379
LS++EG+ GSPEKPLSDLG LSY AYW +++ L H + I+I +S + M DI
Sbjct: 880 LSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIA 939
Query: 380 HTAKALEILRFYRGQHVLYLNSDVMXX--XXXXXXXXXXSIDPQKLIWTP 427
T + L ++ G+ V+ ++ +DP L WTP
Sbjct: 940 TTLQHLHMIDKRDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTP 989
>SPAC17G8.13c [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 407
Score = 250 bits (639), Expect = 3e-66
Identities = 125/282 (44%), Positives = 182/282 (64%), Gaps = 3/282 (1%)
Query: 149 TQNQNEVARVRNLNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERY 208
TQ + + ++ + G Y I+PWY SPYP E + +YI + L+Y S +R+
Sbjct: 91 TQLRTPPPQPTSIRYLYFGTYRIKPWYTSPYPEEYSCAKNLYICESCLKYMNSDHVLQRH 150
Query: 209 RKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFY 268
+ KC+ +PPG+EIYRD +S FE+DG++Q +C+NLCLL+K+FL K LYYDV+PFLFY
Sbjct: 151 KMKCSWSYPPGDEIYRDKNISIFEVDGQRQPIYCQNLCLLAKMFLHSKMLYYDVEPFLFY 210
Query: 269 CMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGKV 328
+T D ++GYFSKEK SA YNV+CILTLP YQR GYG LI+FSY L++ EGK+
Sbjct: 211 VLTEFDGQECKVIGYFSKEKRSASDYNVSCILTLPIYQRRGYGVFLIDFSYLLTQVEGKL 270
Query: 329 GSPEKPLSDLGLLSYRAYWADTLIKLLVEHGQEITIDEVSSISSMTTTDILHTAKALEIL 388
GSPEKPLSDLGL++YR+YW + K L+E I+I+ ++ +SM D++ T ++L +
Sbjct: 271 GSPEKPLSDLGLVTYRSYWKMRVAKALLEITTPISINAIAKSTSMVCDDVISTLESLSVF 330
Query: 389 RF--YRGQHVLYLNSDVMXXXXXX-XXXXXXSIDPQKLIWTP 427
++ + ++VL L D + ++P+ L WTP
Sbjct: 331 KYDPLKKKYVLQLKRDELENVYKAWNIKHPQRVNPKLLRWTP 372
>CE23850 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 550
Score = 245 bits (625), Expect = 1e-64
Identities = 148/444 (33%), Positives = 238/444 (53%), Gaps = 85/444 (19%)
Query: 4 GEEKEPGIPQKVDSIDEIFVGCKSWVLKDGQDRLAEILSINSRRDPPK------------ 51
G + EP Q + I++ ++ + +++ + +A I+ I+ R+ P +
Sbjct: 22 GNDSEPPQQQIMPIINKRYM-VEKFIINTVKKVVAVIIHIDFRKPPQEVRTNNYKSIENH 80
Query: 52 --------FYVHYEDFNKRLDEWITADRLQIDKEVIFPRPXXXXXXXXXXXXXXXXXXSA 103
+YVHYE+ ++R DEWIT D++ +++ V+ P
Sbjct: 81 EQGAKELMYYVHYEELDRRNDEWITLDKILVNEVVVEP---------------------- 118
Query: 104 TPQAASATPDGGDVMDLDNLNVQGIP----NEDISRE-----DEIKKLRT--------SG 146
P V DL V G P + ++R +E L+T +
Sbjct: 119 ----VIKVPTKAPVEDLHKEIVVGPPVIKPSGALTRSQRRTLEEYSHLKTDLNDLDATTA 174
Query: 147 SMTQNQNEVARVRNLNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYE 206
+ + E +V+N+ ++ +G +EI WY+SP+P + + D+ Y+ ++ L Y ++++
Sbjct: 175 RLEREHEERTKVKNIPQITIGAHEILAWYYSPFPPDCENLDI-YMCEYCLLYTPHHERFK 233
Query: 207 RYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRT-----------------WCRNLCLLS 249
++ C +R PPGNEIYR D++S +E+DG Q+ +C+ LCLLS
Sbjct: 234 QHIDTCKVRQPPGNEIYRKDHLSVYEVDGSGQKLFQPFFAPFPPKLPIFQLYCQCLCLLS 293
Query: 250 KLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQYQRMG 309
KLF+DHKTLY+DVD F+FY + DE G HIVGYFS+E ESA+ N+ACI+ P +Q+ G
Sbjct: 294 KLFMDHKTLYFDVDDFMFYVLCETDEHGAHIVGYFSREVESAN--NLACIMVFPPFQKKG 351
Query: 310 YGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKLL-VEHGQEITIDEVS 368
YG+LLI+FSYELS++EG +G PEKPLSDLG +SYR+YW L+KL + G +T +S
Sbjct: 352 YGKLLIQFSYELSRREGYIGMPEKPLSDLGKVSYRSYWWWRLMKLFHIHQGHTVTATFLS 411
Query: 369 SISSMTTTDILHTAKALEILRFYR 392
+ S + DI+ T + + R Y+
Sbjct: 412 NESGIAVDDIVSTLITMRMCRQYK 435
>7291743 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 2271
Score = 245 bits (625), Expect = 1e-64
Identities = 114/229 (49%), Positives = 162/229 (69%), Gaps = 5/229 (2%)
Query: 166 MGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIYRD 225
+GK++IE WY SP+P E +++ +F L+Y S+ +R++ KC + PPG EI+R
Sbjct: 717 IGKWDIETWYSSPFPQEYARLLKLFLCEFCLKYTKSRSVLDRHQNKCIWKQPPGTEIFRQ 776
Query: 226 DYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFS 285
+S FE+DG + +C+NLCLL+K FLDHKTLYYDV+PFLFY +T+ D+ G H+VGYFS
Sbjct: 777 GNISVFEVDGNVNKIYCQNLCLLAKFFLDHKTLYYDVEPFLFYILTKNDQSGCHLVGYFS 836
Query: 286 KEKESADAYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRA 345
KEK YNV+CILT+PQYQR GYGR LI+FSY LS++EG++G+PEKPLSDLG LSY +
Sbjct: 837 KEKHCTQKYNVSCILTMPQYQRQGYGRFLIDFSYLLSREEGQLGTPEKPLSDLGRLSYFS 896
Query: 346 YWADTLIKLLVEHGQ--EITIDEVSSISSMTTTDILHTAKALEILRFYR 392
YW +++ L +H +IT +++ + + +DI A A E+L F +
Sbjct: 897 YWKSVVLEYLYKHRNYTKITFKDIAIKTGLAISDI---ALAFELLNFIK 942
>YBL052c [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 831
Score = 238 bits (607), Expect = 1e-62
Identities = 122/291 (41%), Positives = 189/291 (64%), Gaps = 26/291 (8%)
Query: 122 NLNVQGIPNEDISREDEIKKLRTSGSMTQNQNEVARVRNLNKVIMGKYEIEPWYFSPYPI 181
N NV + + +E+E +K R G + + +N+V + +++ YEI+PWY SP+P
Sbjct: 235 NGNVSLCNHNETDQENEDRKKR-KGKVPRIKNKVW-FSQIEYIVLRNYEIKPWYTSPFPE 292
Query: 182 ELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTW 241
+ +V+I +F L+Y S+ + R++ KC PPGNEIYRD +S +EIDGR+ +
Sbjct: 293 HINQNKMVFICEFCLKYMTSRYTFYRHQLKCLTFKPPGNEIYRDGKLSVWEIDGRENVLY 352
Query: 242 CRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGH---------HIVGYFSKEKESAD 292
C+NLCLL+K F++ KTLYYDV+PF+FY +T R++ + H VGYFSKEK +++
Sbjct: 353 CQNLCLLAKCFINSKTLYYDVEPFIFYILTEREDTENHPYQNAAKFHFVGYFSKEKFNSN 412
Query: 293 AYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYW----A 348
YN++CILTLP YQR GYG+ L+EFSY LS+KE K G+PEKPLSDLGLL+YR +W A
Sbjct: 413 DYNLSCILTLPIYQRKGYGQFLMEFSYLLSRKESKFGTPEKPLSDLGLLTYRTFWKIKCA 472
Query: 349 DTLIKLL-----------VEHGQEITIDEVSSISSMTTTDILHTAKALEIL 388
+ L+KL + Q++++++++ ++ M TD++ + L++L
Sbjct: 473 EVLLKLRDSARRRSNNKNEDTFQQVSLNDIAKLTGMIPTDVVFGLEQLQVL 523
>Hs20549811 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 194
Score = 234 bits (597), Expect = 2e-61
Identities = 107/193 (55%), Positives = 141/193 (72%)
Query: 161 LNKVIMGKYEIEPWYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGN 220
+ + G+Y+++ WY SPYP E +Y+ +F L+Y S+ ++ KC +HP G+
Sbjct: 2 IKTIAFGRYDLDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQMILRQHMAKCVWKHPLGD 61
Query: 221 EIYRDDYVSFFEIDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHI 280
EIYR VS FE+DG+K + +C+NLCLL+KLFLDHKTLYYDV+PFLFY MT D G H+
Sbjct: 62 EIYRKGSVSVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHL 121
Query: 281 VGYFSKEKESADAYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGL 340
+GYFSKEK S YNV+CILT+PQY R GYG++LI+FSY LSK E KVGSPE PLSDLGL
Sbjct: 122 IGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPECPLSDLGL 181
Query: 341 LSYRAYWADTLIK 353
+S +YW + L++
Sbjct: 182 ISCCSYWKEVLLR 194
>7301677 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 421
Score = 209 bits (533), Expect = 5e-54
Identities = 100/270 (37%), Positives = 161/270 (59%), Gaps = 3/270 (1%)
Query: 131 EDISREDEIKKLRTSGSMTQNQNEVARVRNLNKVIMGKYEIEPWYFSPYPIELTDEDVVY 190
+D R++ I ++ + +V +RN+ KV G+YEIE SPYP+ +Y
Sbjct: 116 DDRQRQETIDNEKSDVQKEKEDAKVKVIRNIEKVQFGRYEIETTSSSPYPVINDKATTIY 175
Query: 191 IDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSK 250
+ +F L+Y +K Y + C R PPG+ +YR D + +E+DG K++ +C+ LCL+SK
Sbjct: 176 VCEFCLKYMCLRKSYSYHLYDCKKRCPPGSLLYRKDNIYIYEVDGHKEQLYCQCLCLMSK 235
Query: 251 LFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQYQRMGY 310
LFL++K + Y FLFY + +D+ G H GYF++EK + N+ CIL LP Y R GY
Sbjct: 236 LFLENKKILYSSSSFLFYILCLKDKDGEHFAGYFAREKTMLN-INLNCILVLPPYMRKGY 294
Query: 311 GRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKLLVEHGQE--ITIDEVS 368
G+LLI+ SYE+S++E +G P+KPLS + L Y +YW L+ LL H +TI+E+S
Sbjct: 295 GKLLIDLSYEISRREACIGGPKKPLSKVARLCYLSYWGHILLNLLRHHSSPDLVTIEELS 354
Query: 369 SISSMTTTDILHTAKALEILRFYRGQHVLY 398
+ DI+ T + + + ++Y+ H+++
Sbjct: 355 KATGFREEDIISTLEFMGMTKYYKVDHIMF 384
>CE06262 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 1271
Score = 205 bits (521), Expect = 1e-52
Identities = 104/261 (39%), Positives = 155/261 (58%), Gaps = 8/261 (3%)
Query: 131 EDISREDEIKKLRTSGSMTQNQNEVARVRNLNKVIMGKYEIEPWYFSPYPIELTDEDVVY 190
+ +S +E + S ++ E AR+ ++ G + ++ WY SP+P E + ++
Sbjct: 207 KSVSDRNEFSPAQISEIYRSSKGEQARLPE--RIHFGAFIMKTWYGSPFPAEFINVKKLF 264
Query: 191 IDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEIDGRKQRTWCRNLCLLSK 250
I +F Y S + + + KKC LR PPG EIYR +S FE+DGR Q+ +C+ LCL+S+
Sbjct: 265 ICEFCFFYARSDEIMQNHAKKCMLRAPPGLEIYRKGDISVFEVDGRLQKEYCQTLCLVSR 324
Query: 251 LFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQYQRMGY 310
+FL+ KT++YD +PF FY +T D++G H GYFSKEK D N++CI+TLP YQ MG
Sbjct: 325 MFLESKTVFYDTEPFFFYIVTINDDIGCHFAGYFSKEKYEPDVNNLSCIMTLPCYQEMGL 384
Query: 311 GRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKLL------VEHGQEITI 364
GR LI+ SY LS+KE G PE+PLS+LG +Y YW T+ L +E G I+I
Sbjct: 385 GRFLIDISYALSRKEKWFGGPEQPLSELGRKAYGGYWRTTIASCLGRLKDELEFGSGISI 444
Query: 365 DEVSSISSMTTTDILHTAKAL 385
++ + + DIL +L
Sbjct: 445 KMIADDTGVNCHDILEVVCSL 465
>7297249 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 769
Score = 181 bits (459), Expect = 2e-45
Identities = 95/208 (45%), Positives = 134/208 (63%), Gaps = 7/208 (3%)
Query: 116 DVMDLDNL-NVQG-IPNEDISREDEIKKLRTSGSMTQNQNEVARVRNLNKVIMGKYEIEP 173
DV D D N+ G +P+ D+ E + + S + ++ + + + MGKY+++
Sbjct: 482 DVTDEDREPNLAGLVPDYDLQLFREAQA-QASERIEDELKDLPVGKGIKYISMGKYKMKV 540
Query: 174 WYFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEI 233
WY SPYP + +YI +F L+Y S+ +R+ +KC RHPPG+EIYR + +++
Sbjct: 541 WYQSPYPDDAARLPKMYICEFCLRYQKSETGIKRHAEKCVWRHPPGDEIYRKGKLQVWQV 600
Query: 234 DGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKE----KE 289
DG++ + +C++LCLL+K FLDHKTLYYDV+PFLFY MT D G HIVGYFSK +E
Sbjct: 601 DGKRYKQYCQHLCLLAKFFLDHKTLYYDVEPFLFYIMTLADVDGCHIVGYFSKHIPFLQE 660
Query: 290 SADAYNVACILTLPQYQRMGYGRLLIEF 317
YNV+CILTLP YQR GYGRLLI+F
Sbjct: 661 KNSFYNVSCILTLPPYQRKGYGRLLIDF 688
>CE27818 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 617
Score = 180 bits (457), Expect = 3e-45
Identities = 96/255 (37%), Positives = 143/255 (55%), Gaps = 4/255 (1%)
Query: 175 YFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIYRDDYVSFFEID 234
Y S Y L +Y F L K+ + C +HPPG EIYR+D ++FFE+D
Sbjct: 349 YSSAYEEPLHSSAHLYACKFCLHTTNLKEDLIVHWDICNAKHPPGTEIYRNDGLAFFEVD 408
Query: 235 GRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAY 294
G Q+ +C++LCL+SKLF+ KTLY +V+ F FY + G+ IVGYFSKEK +
Sbjct: 409 GAVQKKYCQDLCLISKLFIASKTLYDEVETFKFYVLCEITTEGYVIVGYFSKEKNPSKNN 468
Query: 295 NVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKL 354
N++C+L LP Q+MGYGRLLI+ SYELS+ E ++G PE PLSDLG+L+YR YW +L+
Sbjct: 469 NLSCLLVLPMVQKMGYGRLLIDMSYELSRLEMRIGHPEHPLSDLGILAYRGYWRSSLLCY 528
Query: 355 LVEHG--QEITIDEVSSISSMTTTDILHTAKALEILRFYRGQHVLYLNSDVMXXXXXXXX 412
+ EH + I ++ + + DI++ ++ G + + + +
Sbjct: 529 IREHRNYDRLNIKDMCLATRIAPVDIVNQLMLDNMIVLKGGVYSIKIGKRALKFPLSQCR 588
Query: 413 XXXXSIDPQKLIWTP 427
+DP +L W P
Sbjct: 589 RRF--VDPSQLFWKP 601
>ECU09g1310 [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 288
Score = 140 bits (352), Expect = 5e-33
Identities = 91/292 (31%), Positives = 152/292 (51%), Gaps = 28/292 (9%)
Query: 119 DLDNLNVQGIPNEDISREDEIKKLRTSGSMTQNQNEVARVRNLNKVIMGK----YEIEPW 174
D + +++ G E + ++K + T V R + + + G + W
Sbjct: 4 DSEEMDLLGNDPEFMEYRRAMEKDHKATDATPQMEFVKRNVEVTQAVFGDELLGFRNRVW 63
Query: 175 YFSPYPIELTDEDVVYIDDFSLQYFGSKKQYERYRKKCTLRHPPGNEIY--RDDYVSFFE 232
FS D++VVYI D L + R+RK+C+ + PG +Y +D+ +S E
Sbjct: 64 LFS-------DKNVVYICDRCLHQYWDSTSLGRHRKECS-QGIPGRHVYTDKDEGISVIE 115
Query: 233 IDGRKQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESAD 292
IDG + CR +C + + F+ KTL+ DVD +LFY + +G + G+FSKEKES +
Sbjct: 116 IDGGCESVLCRRICTIGRAFIHRKTLHLDVDGYLFYVLL----IGGRVAGFFSKEKES-E 170
Query: 293 AYNVACILTLPQYQRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLI 352
+N++C+L LP ++ GYG L+I+ SY L G+PEKPLS G Y+ YW + ++
Sbjct: 171 KHNLSCLLVLPPHRSRGYGSLMIDLSYILGP-----GTPEKPLSKEGRAVYKRYWRNMVL 225
Query: 353 KLLVE-HGQEITIDEVSSISSMTTTDILHTAKALEILRFYRGQHVLYLNSDV 403
K L + G+E++I +S+ S ++ D +H LE+L H+ ++ V
Sbjct: 226 KTLRKMGGEEMSICSISAESGLSIDDTIH---GLELLGINPESHIYDVSGKV 274
>YMR127c [B] KOG2747 Histone acetyltransferase (MYST family)
Length = 338
Score = 134 bits (338), Expect = 2e-31
Identities = 73/220 (33%), Positives = 122/220 (55%), Gaps = 7/220 (3%)
Query: 187 DVVYIDDFSLQYFGSKKQYERYRKKCTLRHP-PGNEIYRDDYVSFFEIDGRKQRTWCRNL 245
D +++ ++ +Y + ++ + C ++ PG Y+ + + G K + +C+ L
Sbjct: 98 DTLFVCEYCFKYTDDQTRFVGHVASCPFQYRVPGKIKYKSPEYTIRRVKGSKYQLFCQCL 157
Query: 246 CLLSKLFLDHKTLYYDVDPFLFYCMTRRDELGHHIVGYFSKEKESADAYNVACILTLPQY 305
CL +KL+LD+K++Y+ VD + FY + +G+FSK+ S N+ACIL P Y
Sbjct: 158 CLFTKLYLDNKSMYFKVDHYEFYIVYETGSTKP--MGFFSKDLVSYQQNNLACILIFPPY 215
Query: 306 QRMGYGRLLIEFSYELSKKEGKVGSPEKPLSDLGLLSYRAYWADTLIKLLVE----HGQE 361
QR G G LLIEFSY+LS+ EG + PE PLS GL+ Y YW+ L L+E H +
Sbjct: 216 QRRGLGLLLIEFSYKLSQLEGVISGPEVPLSPFGLIGYLKYWSQILCWHLIEGDLAHYDK 275
Query: 362 ITIDEVSSISSMTTTDILHTAKALEILRFYRGQHVLYLNS 401
+T++++S ++ M D++ T K L + ++ LNS
Sbjct: 276 VTLEDLSIVTGMRVNDVILTLKHLNCIGENNQIYLQSLNS 315
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.139 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,887,040
Number of Sequences: 60738
Number of extensions: 1165898
Number of successful extensions: 2532
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2474
Number of HSP's gapped (non-prelim): 34
length of query: 439
length of database: 30,389,216
effective HSP length: 109
effective length of query: 330
effective length of database: 23,768,774
effective search space: 7843695420
effective search space used: 7843695420
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)