ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI2995 good R KOG2823 General function prediction only Cellular protein (glioma tumor suppressor candidate region gene 2)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI2995 1057103 1055772 -444
(444 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL146c [R] KOG2823 Cellular protein (glioma tumor suppressor ca... 292 8e-79
SPAC22F8.09 [R] KOG2823 Cellular protein (glioma tumor suppresso... 116 8e-26
At2g40430 [R] KOG2823 Cellular protein (glioma tumor suppressor ... 54 6e-07
Hs7657130 [R] KOG2823 Cellular protein (glioma tumor suppressor ... 52 2e-06
>YPL146c [R] KOG2823 Cellular protein (glioma tumor suppressor candidate
region gene 2)
Length = 455
Score = 292 bits (747), Expect = 8e-79
Identities = 148/263 (56%), Positives = 201/263 (76%), Gaps = 5/263 (1%)
Query: 7 RPAQYKQSSRKGKKAWRKNIDISDVERKLEEKQILETTHGKQNLTELSDDALFAVDTEGD 66
+P+QYKQSSRKGKKAWRKNID+SDVE+ +E+K E THG ++T L +DALF VD EGD
Sbjct: 9 KPSQYKQSSRKGKKAWRKNIDLSDVEQYMEKKIDHEITHGTSDITSLQNDALFHVDVEGD 68
Query: 67 QVLKQKLVKRKAIKKTLKSTEILESIKSKSKVPALTNPKTANKKHDKIQGVSKKELDRLL 126
++LK KL+KRK IKK LKS EIL+++K+ SK+ AL + K ++ +KIQGVSK EL +L+
Sbjct: 69 EILKNKLIKRKQIKKVLKSKEILDAVKTNSKIAALNHHKNSSGNPNKIQGVSKHELKKLM 128
Query: 127 ALAGKKIGESKLKARVAKEGLVKSGSLDLWGEDAG---KEVKVPSGLKLKIAPEEVEKLP 183
ALAG+ GESK+K RVAK+GLVK+ + DLWGE++ ++VK+PSG+KL + E+ +++P
Sbjct: 129 ALAGRVHGESKIKNRVAKDGLVKTTAGDLWGEESNSKKQKVKLPSGIKLDV--EKKDQIP 186
Query: 184 NGFLKQSTTSWSVATVKPDSIARVPEIVKERDVIPHAGKSYNPSKEEWEALISTEYEGEL 243
LK+STTSWS A+V+P ++ P VKE IPHAGKSYNP+ + W LI+ EY+ E
Sbjct: 187 EELLKKSTTSWSTASVRPSTLDIEPIAVKEFTEIPHAGKSYNPNNKAWSELINKEYKEEK 246
Query: 244 INEQRRIALEQYKQRIQHLMDTI 266
E RIALE+YK+RI+HLM+T+
Sbjct: 247 AREDERIALEKYKERIRHLMETL 269
Score = 118 bits (296), Expect = 2e-26
Identities = 52/69 (75%), Positives = 66/69 (95%)
Query: 376 HSVMEDNLEVKFSDELSDSLRKLRPEGNLLYDTVRALQSSGRVESRIPIRKGRRYKPRVT 435
+SV+++ LE+KFSDELSDSLRKL+PEGNLLYDTVR LQSSG+VE+R+P+RKGR+YK ++T
Sbjct: 387 YSVIDERLEIKFSDELSDSLRKLKPEGNLLYDTVRKLQSSGKVETRVPVRKGRKYKQKIT 446
Query: 436 EKWTYKDFK 444
EKWT+KDFK
Sbjct: 447 EKWTHKDFK 455
>SPAC22F8.09 [R] KOG2823 Cellular protein (glioma tumor suppressor candidate
region gene 2)
Length = 419
Score = 116 bits (290), Expect = 8e-26
Identities = 99/265 (37%), Positives = 134/265 (50%), Gaps = 42/265 (15%)
Query: 3 GSKDR--PAQYKQSSRKGKKAWRKNIDISDVERKLEEKQILETTHGKQNLTELSDDALFA 60
G K+R P+QYKQSSRK K+AWRKNID+ D+E LE+ + E G N+ +DALF
Sbjct: 2 GIKERNAPSQYKQSSRKNKRAWRKNIDLEDIESGLEQTRDEEIKGG--NVEHKPNDALFV 59
Query: 61 VDTEGDQVLKQKLVKRKAIKKTLKSTEILESIKSKSKVPA-LTNPKTANKKHDKIQGVSK 119
+DT GD + ++ RK I K LK +ILE+ S KV + LTN T + K KI S+
Sbjct: 60 IDTLGDDRIAKR--SRKKI-KPLKVDQILENKSSIEKVHSHLTNNSTESNKKGKI--FSR 114
Query: 120 KELDRLLALAGKKIGESKLKARVAKEGLVKS----GSLDLWGEDAGKEVKVPSGLKLKIA 175
KEL+RL AL K + L A A L + S D+W + V +P
Sbjct: 115 KELNRLQALVYK--NKDGLTATSAASELKNTKQPKESYDVW--ETNPTVTIPVK-----R 165
Query: 176 PEEVEKLPNGFLKQSTTSWSVATVKPDSIARVPEIVKERDVIPHAGKSYNPSKEEWEALI 235
P + KLP + + A+VP + VI G SYNP W L+
Sbjct: 166 PSTLSKLPESLTENN--------------AKVPNV-----VIADPGMSYNPDAAAWMKLL 206
Query: 236 STEYEGELINEQRRIALEQYKQRIQ 260
T+ EL EQ+RI+ + K+RIQ
Sbjct: 207 DTKGSEELKKEQKRISELEEKERIQ 231
Score = 63.5 bits (153), Expect = 6e-10
Identities = 28/68 (41%), Positives = 44/68 (64%)
Query: 376 HSVMEDNLEVKFSDELSDSLRKLRPEGNLLYDTVRALQSSGRVESRIPIRKGRRYKPRVT 435
H + + LE+K DEL+ SLR+L+PEGNL D +LQ V +P+ K +Y+ ++
Sbjct: 345 HRLPNNPLEIKLGDELTSSLRELKPEGNLFADRYLSLQQRAMVPPSLPVLKKSKYRAKIK 404
Query: 436 EKWTYKDF 443
EK+++KDF
Sbjct: 405 EKYSHKDF 412
>At2g40430 [R] KOG2823 Cellular protein (glioma tumor suppressor candidate
region gene 2)
Length = 413
Score = 53.5 bits (127), Expect = 6e-07
Identities = 57/231 (24%), Positives = 92/231 (39%), Gaps = 58/231 (25%)
Query: 13 QSSRKGKKAWRKNIDISDVERKLEEKQILETTHGKQNLTELSDDALFAVDTEGDQVLKQK 72
++SRKGKKAWR NI D+E EK + G NL+ + LF VD D +K+K
Sbjct: 6 KTSRKGKKAWRANISSEDIE-DFFEKTTRDALSG-GNLSAAPSEDLFHVDKSHDLPVKRK 63
Query: 73 LVKRKAIKKTLKSTEILESIKSKSKVPALTNPKTANKKHDKIQGVSKKELDRLLALAGKK 132
+ K + ++ L+ IL+ VP+ +KK I+ + K++ K
Sbjct: 64 IEKHR--ERVLRVDSILKKNPFVQLVPSSKPKLKKSKKTIVIEDKAPKQVQ-------KS 114
Query: 133 IGESKLKARVAKEGLVKSGSLDLWGEDAGKEVKVPSGLKLKIAPEEVEKLPNGFLKQSTT 192
+G+ + A DLWG+D+ E +
Sbjct: 115 VGDDSVMA-------------DLWGDDSKGEHE--------------------------- 134
Query: 193 SWSVATVKPDSIARVPEIVKERDVIPHAGKSYNPSKEEWEALISTEYEGEL 243
P I + P I+ + I H G SYNP+ E + +++ E+
Sbjct: 135 ------SNPRKIFKNPSIISAVE-IEHPGCSYNPTTESHQDMLAEAVAQEM 178
>Hs7657130 [R] KOG2823 Cellular protein (glioma tumor suppressor candidate
region gene 2)
Length = 478
Score = 52.0 bits (123), Expect = 2e-06
Identities = 23/63 (36%), Positives = 41/63 (64%)
Query: 382 NLEVKFSDELSDSLRKLRPEGNLLYDTVRALQSSGRVESRIPIRKGRRYKPRVTEKWTYK 441
+++V+ S EL+DSLR L+PEGN+L D ++ Q +E R + R+YK ++ EK ++
Sbjct: 415 DIDVQLSSELTDSLRTLKPEGNILRDRFKSFQRRNMIEPRERAKFKRKYKVKLVEKRAFR 474
Query: 442 DFK 444
+ +
Sbjct: 475 EIQ 477
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.309 0.129 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,662,281
Number of Sequences: 60738
Number of extensions: 802773
Number of successful extensions: 2644
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2632
Number of HSP's gapped (non-prelim): 8
length of query: 444
length of database: 30,389,216
effective HSP length: 110
effective length of query: 334
effective length of database: 23,708,036
effective search space: 7918484024
effective search space used: 7918484024
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)