ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3024 good LD KOG4139 Cell cycle control, cell division, chromosome partitioning Protein kinase essential for the initiation of DNA replication
r_klactVI3024 good LD KOG4139 Replication, recombination and repair Protein kinase essential for the initiation of DNA replication
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3024 1065656 1067530 625
(625 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR052c [LD] KOG4139 Protein kinase essential for the initiation... 266 5e-71
SPCC550.13 [LD] KOG4139 Protein kinase essential for the initiat... 80 7e-15
SPBC1778.04 [LD] KOG4139 Protein kinase essential for the initia... 59 2e-08
>YDR052c [LD] KOG4139 Protein kinase essential for the initiation of DNA
replication
Length = 704
Score = 266 bits (681), Expect = 5e-71
Identities = 145/315 (46%), Positives = 198/315 (62%), Gaps = 29/315 (9%)
Query: 131 RLSNKELIDWQNNWKKIMKRDTFIYFDCPEVAN---------DNRKDVLRRAFSTLGAKV 181
R++ KEL++WQ NWKKIMKRD+ IYFD + D R+D+L+R F TLGA++
Sbjct: 103 RVTPKELLEWQTNWKKIMKRDSRIYFDITDDVEMNTYNKSKMDKRRDLLKRGFLTLGAQI 162
Query: 182 KQFFDHEVTIVITSRKITNYSQLPDTDILQRAHKRGYMKIWTLEKAARFLTNMDVDLKEM 241
QFFD VTIVIT R + N L DTDIL RA K+ YMK+W+ EKAARFL N+DVDL +
Sbjct: 163 TQFFDTTVTIVITRRSVENIYLLKDTDILSRA-KKNYMKVWSYEKAARFLKNLDVDLDHL 221
Query: 242 ERDSISGKSIPAXXXXXXXXXXKLFGSNERDPKTKRDDLHYFKHPHVYLYDLAQINAPLI 301
+ + S+ A KL+G +RDP+TKRDD+HYFK+PHVYLYDL Q AP+I
Sbjct: 222 SKTKSA--SLAAPTLSNLLHNEKLYGPTDRDPRTKRDDIHYFKYPHVYLYDLWQTWAPII 279
Query: 302 TLEWKAQDINNKKKHIYPTIKPGSFGRCPFQGDETADELQPRRIIKRYKRDKANESYAMK 361
TLEWK Q++ N + YP +K GSFGRCPF GD DE +R++KRY RDKAN+ YA++
Sbjct: 280 TLEWKPQELTNLDELPYPILKIGSFGRCPFIGDRNYDESSYKRVVKRYSRDKANKKYALQ 339
Query: 362 LRLLYQTSAEPATLSSSETSDYEGDDAILSFPDPSSKEPIILPYQNVYNNSGAQYNKLVN 421
LR L+Q A+ L++S +D +K I +P+ N+S + K +
Sbjct: 340 LRALFQYHAD-TLLNTSSVND-------------QTKNLIFIPH--TCNDSTKSFKKWMQ 383
Query: 422 SMSR-FKQPKLPRGD 435
++ F++ +L + D
Sbjct: 384 EKAKNFEKTELKKTD 398
Score = 64.7 bits (156), Expect = 4e-10
Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 7/89 (7%)
Query: 532 KLHNH---NIAASGVNQTNPTSTVSKQQLPALTPQRLHQPIGRQT---AGYCENCKVKYD 585
K+HN S TST A T Q QP+ ++T +GYCENC+VKY+
Sbjct: 611 KVHNDIKITTTESPTASKKSTSTNVTLHFNAQTAQTA-QPVKKETVKNSGYCENCRVKYE 669
Query: 586 SLEAHVSTERHIAFASKDEHFQGVDSMIQ 614
SLE H+ +E+H++FA D +F+ +DS+I+
Sbjct: 670 SLEQHIVSEKHLSFAENDLNFEAIDSLIE 698
>SPCC550.13 [LD] KOG4139 Protein kinase essential for the initiation of DNA
replication
Length = 545
Score = 80.5 bits (197), Expect = 7e-15
Identities = 58/197 (29%), Positives = 94/197 (47%), Gaps = 13/197 (6%)
Query: 137 LIDWQNNWKKIMKRDTFIYFDC-PEVANDNRKDVLRRAFSTLGAKVKQFFDHEVTIVITS 195
L +W+ +KK F C P VA+ +K + + LG V+ FF VT V T
Sbjct: 138 LQEWKRQYKKAFPHFRFYLDGCDPSVAHRVKKQIQQ-----LGGHVETFFSGNVTHVATV 192
Query: 196 RKITNYS-QLPDTDILQRAHKRGYMKIWTLEKAARFLTNMDVDLKEMERDSISGKSIPAX 254
R I + S + D++ +A + MKIW++EK + L E ++ + + +
Sbjct: 193 RAIQDVSVKYAKQDVITKARQLN-MKIWSMEKLCNRVLKT---LMENDQCTTNAPTKQGN 248
Query: 255 XXXXXXXXXKLFGSNERDPKTKRDDLHYFKHPHVYLYDLAQINAPLITLEWKAQDINNKK 314
K+ G+NERD R D +F+ P++Y++D+A I P++ EW Q +
Sbjct: 249 DLSYLLYVEKVQGTNERDLSVPRQDFVHFRGPYLYVHDIANIYKPILLREW--QKPLPDR 306
Query: 315 KHIYPTIKPGSFGRCPF 331
+PT + S GRCPF
Sbjct: 307 DVPWPTFRATSIGRCPF 323
Score = 50.8 bits (120), Expect = 6e-06
Identities = 18/44 (40%), Positives = 31/44 (69%)
Query: 575 GYCENCKVKYDSLEAHVSTERHIAFASKDEHFQGVDSMIQCVQQ 618
GYCENC+ K+D+ E+H+ + RH FA +++F+ +D + VQ+
Sbjct: 497 GYCENCREKFDNFESHIRSSRHRRFAENNDNFKDLDELFALVQR 540
>SPBC1778.04 [LD] KOG4139 Protein kinase essential for the initiation of DNA
replication
Length = 474
Score = 59.3 bits (142), Expect = 2e-08
Identities = 53/193 (27%), Positives = 91/193 (46%), Gaps = 17/193 (8%)
Query: 140 WQNNWKKIMKRDTFIYFDCPEVANDNRKDVLRRAFSTLGAKVKQFFDHEVTIVITSRKIT 199
WQ +++ F YFD V + ++ V ++ + LGAKV F EVT IT+R T
Sbjct: 120 WQRDYRLAFPNFIF-YFD--NVDEEIKRRVTQK-INNLGAKVATLFTFEVTHFITTRT-T 174
Query: 200 NYSQLPDTDILQRAHKRGYMKIWTLEKAA-RFLTNMDVDLKEMERDSISGKSIPAXXXXX 258
+ D+L + K MKIW L+K R L + + DS+ S A
Sbjct: 175 DPEMCQPNDVLYLS-KTANMKIWLLDKLLNRILFTL------LNSDSLVNTS--ASCLQS 225
Query: 259 XXXXXKLFGSNERDPKTKRDDLHYFKHPHVYLYDLAQINAPLITLEWKAQDINNKKKHIY 318
K++G++++D ++ YF+ + + DL+Q P+ EW + + + ++
Sbjct: 226 LLDGEKVYGTSDKDFYVPSKNVEYFREYFLCIRDLSQYYKPIAVREW--EKTLDSGEILW 283
Query: 319 PTIKPGSFGRCPF 331
P++ + GRCPF
Sbjct: 284 PSLAITAQGRCPF 296
Score = 53.5 bits (127), Expect = 9e-07
Identities = 29/79 (36%), Positives = 46/79 (57%), Gaps = 3/79 (3%)
Query: 543 VNQTNPTSTVSKQQLP-ALTPQRL-HQPIGRQT-AGYCENCKVKYDSLEAHVSTERHIAF 599
+N+ N + S +Q P A L H+ + +T +GYCENC +Y LE H+ + H F
Sbjct: 391 INKQNTLANQSPRQPPNAFDADPLAHKKVKIETKSGYCENCCERYKDLERHLGGKHHRRF 450
Query: 600 ASKDEHFQGVDSMIQCVQQ 618
A KDE+FQG+D + +++
Sbjct: 451 AEKDENFQGLDDLFLLIRR 469
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.131 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,500,089
Number of Sequences: 60738
Number of extensions: 1393929
Number of successful extensions: 2623
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2611
Number of HSP's gapped (non-prelim): 7
length of query: 625
length of database: 30,389,216
effective HSP length: 112
effective length of query: 513
effective length of database: 23,586,560
effective search space: 12099905280
effective search space used: 12099905280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)