ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3087 good R KOG2505 General function prediction only Ankyrin repeat protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3087 1087802 1089664 621
(621 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR049w [R] KOG2505 Ankyrin repeat protein 509 e-144
SPCC1827.04 [R] KOG2505 Ankyrin repeat protein 231 2e-60
At1g01930 [R] KOG2505 Ankyrin repeat protein 104 3e-22
CE26941 [R] KOG2505 Ankyrin repeat protein 101 4e-21
Hs8922413 [R] KOG2505 Ankyrin repeat protein 77 6e-14
>YDR049w [R] KOG2505 Ankyrin repeat protein
Length = 632
Score = 509 bits (1310), Expect = e-144
Identities = 272/609 (44%), Positives = 375/609 (60%), Gaps = 19/609 (3%)
Query: 1 MSDRIQKNDLYVYDLSDEILSSLQLISFDSDMNEVKVVHSDXXXXXXXXXX--------X 52
M+ ++KNDLY++DLS+++L+SL+L+SFDS + EV+V +
Sbjct: 9 MTGSLKKNDLYIFDLSEQLLNSLKLMSFDSTLREVEVEKTSDNDRNKESGDLQIARKKVT 68
Query: 53 XTVPSCASCGINAFPNDNSDPRYHFKTDLHKFNIKRRVYGLSPVDEQEFRQLIKSKETAT 112
V C+ C ++ + ++ + H++TD H N+KR + GL + +EF LI +
Sbjct: 69 SNVMRCSVCQMSF--DSRNEQKAHYQTDYHLMNVKRNLRGLDILSVEEFDALISKEHGIK 126
Query: 113 AXXXXXXXXXXXXXXXXXXXXXXXST--RGGEQLTAILEHELQDLMINDNQTGPVSHLNT 170
+ + + I+E++LQ L +++ +SH+NT
Sbjct: 127 SEDENSGGEQTSSDHEESEEASDRDPDLQTNNYMETIIENDLQKLGFQKDESDAISHINT 186
Query: 171 QSPLIFMHSAELSGPRIFGAYKVLFNAEELKCPLKSIHHWKNQDKTEHFSVLFMIGGGHF 230
QSP I+ S L + YK LFN L P +++ W +Q+ S LFM+GGGHF
Sbjct: 187 QSPYIYFKSKYLQKNEVLAIYKSLFNKRSLSNPNEALTFWNSQENPMAISALFMVGGGHF 246
Query: 231 AGAVVSHQKIPTNGNNKNKYILSLQEQSVQFLEQKTFHRYTTRRKQGGSQSANDNAKGKA 290
AGA+VSHQ++ GN +K +L EQ+V FLE KTFHRYTTRRKQGGSQSA DNAKGKA
Sbjct: 247 AGAIVSHQRLNVKGN-AHKKDETLIEQAVNFLEHKTFHRYTTRRKQGGSQSAMDNAKGKA 305
Query: 291 NSAGSTLRRYNEAALKADIQALLKDWEPYIAKCDNIFIRANSVTDRKIFLDNTCISKTDV 350
NSAGS LRRYNE+ALK DIQ +LKDWEPY++KCDNIFIRA +V+D+KIF DNT ++K D
Sbjct: 306 NSAGSALRRYNESALKTDIQGVLKDWEPYLSKCDNIFIRARNVSDKKIFTDNTVLNKGDE 365
Query: 351 KLKSFPFTTMRPSSNELRRAWVQLTYLSITDKPQPKVKK--LQTDHSKNKPRKLTNSPTP 408
++KSFPFTT RP+ EL++AW +L+YL I KP+P K +Q NK + P
Sbjct: 366 RIKSFPFTTNRPTVLELKKAWCELSYLKILPKPEPLAVKETVQKLEVSNKKDEFKEKQEP 425
Query: 409 VPLKTEDEQHTEKLISFIQKSKAPLLISYIKKNNLDVNITLQPSSEYHHTPTMLHYASSH 468
+ +E TE++IS ++K +APLLIS++KKN LD N L+P S+Y TPTMLHYAS
Sbjct: 426 L----LEEIQTEEIISLLKKGRAPLLISFLKKNKLDGNFRLKPESKYSLTPTMLHYASQQ 481
Query: 469 GLKHMVLVLLSTLKADPTITNNVGKTAWDLASDTMVKETFQLARYNLGESFTDWEQSHVS 528
G+K M L+LLS +K DPTI N +G+TAWDL + V+ FQ+ARYNLGESFT+W+++H+
Sbjct: 482 GMKQMALILLSNIKCDPTIKNRLGRTAWDLNRNDDVRHAFQIARYNLGESFTNWDETHIG 541
Query: 529 GALSAEQIDERHXXXXXXXXXXXXXXXXXXXQAAKERIKEEKDAKRGPGMKLGAASSNVQ 588
LS EQ+DE + +AAKE+ + KDA+RGPG KL S Q
Sbjct: 542 QPLSREQVDEINEKKKAIENEKAEKLIKLELEAAKEKQRFAKDAERGPGKKLTNIPSIQQ 601
Query: 589 INLNSLTDD 597
NLNSLTD+
Sbjct: 602 QNLNSLTDE 610
>SPCC1827.04 [R] KOG2505 Ankyrin repeat protein
Length = 600
Score = 231 bits (590), Expect = 2e-60
Identities = 178/605 (29%), Positives = 271/605 (44%), Gaps = 53/605 (8%)
Query: 12 VYDLSDEILSSLQLISFDSDMNEVKVVHSDXXXXXXXXXXXXTVPSCASCGINAFPNDNS 71
++ L ++IL+ L+L + + E + + SC +C I+ +
Sbjct: 9 IFSLPEDILAKLELRE-EYSVEEKTDSANLSNQGDIVDSTQKNISSCVNCQIDNL-HTLD 66
Query: 72 DPRYHFKTDLHKFNIKRRVYGLSPVDEQEFRQLIKSKETATAXXXXXXXXXXXXXXXXXX 131
+ + H K+D H+FN KR++ L PV + EF +I+ + +
Sbjct: 67 ERKSHIKSDWHRFNTKRKITKLPPVSQDEFESIIEDLPESLSGSESETNSESEEDNFQIE 126
Query: 132 XXXXXSTRGGEQLTAILEHELQDLMINDNQTGPVSHLNTQSPLIFMHSAELSG--PRIFG 189
S G+ + N+NQ T SPL + + S P G
Sbjct: 127 KAFKQSLNIGK---------VDSADENNNQ-------RTNSPLTWFQLSNASAEVPTYIG 170
Query: 190 AYKVLFNAEELKCPLKSIHHWKNQDKTEHFSVLFMIGGGHFAGAVVSHQKIPTNGNNKNK 249
YK +F+ + + + +FM+GGGHFA + S++ P + +
Sbjct: 171 VYKHMFSGNNHITKDLLVQQQNHNRQKPLQLAMFMVGGGHFAAMIASNEFNPRDPHVP-- 228
Query: 250 YILSLQEQSVQFLEQKTFHRYTTRRKQGGSQSANDNAKGKANSAGSTLRRYNEAALKADI 309
+ L QKT HRYTTRRKQGGSQ A DN KG +SAGS LRRYNE AL DI
Sbjct: 229 ----------KVLAQKTIHRYTTRRKQGGSQGAADNTKGNIHSAGSGLRRYNEQALIKDI 278
Query: 310 QALLKDWEPYIAKCDNIFIRANSVTDRKIFLD--NTCISKTDVKLKSFPFTTMRPSSNEL 367
Q + KDW + CD IF+RA ++R IF IS D KL+ FPFTT R + +EL
Sbjct: 279 QQVFKDWGKLLETCDLIFVRAIGSSNRSIFFSQPGALISPKDPKLRVFPFTTKRATHSEL 338
Query: 368 RRAWVQLT------YLSITDKPQPKVKKLQTDHSKN-KPRKLTNSPTPVPLKTEDEQHTE 420
R + +L SI+ K Q + +K Q + K + +L K + ++TE
Sbjct: 339 LRCYKELVTPKISHVDSISIKAQEEERKRQAEIEKEIRQSRLQEEERK---KKKLAKYTE 395
Query: 421 KLISFIQKSKAPLLISYIKKNNLDVNITLQPSSEYHHTPTMLHYASSHGLKHMVLVLLST 480
+IS ++ S + Y++ N+L +N P + + HT T LHYA + +V LL
Sbjct: 396 VIISNLKASNIEAFLEYLRSNDLSINFQFYPKNVHLHTSTPLHYAVTQKNAKLVAKLLRN 455
Query: 481 LKADPTITNNVGKTAWDLAS-DTMVKETFQLARYNLGESFTDWEQSHVSGALSAEQIDER 539
ADP + N GKT +++++ + VK+ F +AR+ LGESF DWE + V S EQI ++
Sbjct: 456 -GADPAMLNGNGKTPFEISTGNKEVKDEFLIARHELGESFFDWEAAKVGAPQSREQIQKQ 514
Query: 540 HXXXXX-------XXXXXXXXXXXXXXQAAKERIKEEKDAKRGPGMKLGAASSNVQINLN 592
Q +E+ K + D G G LG + L
Sbjct: 515 RQKAKTKLENQRRDKERQEELRRKEAMQKIEEQSKRDYDKLHGEGHSLGINNVRKVDELQ 574
Query: 593 SLTDD 597
SL+ +
Sbjct: 575 SLSPE 579
>At1g01930 [R] KOG2505 Ankyrin repeat protein
Length = 576
Score = 104 bits (260), Expect = 3e-22
Identities = 118/487 (24%), Positives = 202/487 (41%), Gaps = 76/487 (15%)
Query: 57 SCASCGINAFPNDNSDPRYHFKTDLHKFNIKRRVYGLSPVDEQEFRQLIKSKETATAXXX 116
+C +C I D RYHFK+D+H+ NIK V G + + E++ +L + E+
Sbjct: 73 TCNTCKIEFL--SLQDQRYHFKSDIHRLNIKLSVAGKAILKEEDVDEL--TSESVQDYDV 128
Query: 117 XXXXXXXXXXXXXXXXXXXXSTRGGEQLTAILEHELQD-------LMINDNQTGPVSHLN 169
+ +G ++ + D L+++D ++ VS N
Sbjct: 129 SSISGSEDEAETRPPSFHFDAQKGIDKKKLFFRLQSGDKVSIWKCLIMDDAES--VSFEN 186
Query: 170 TQSPLIFMHSAELSGPRIFGAYKVLFNAEELKCPLKSIHHWKNQDKTEHFSVLFMIGGGH 229
+ S + G + E+ L+++ D+ V+ + GGH
Sbjct: 187 DRGV-----SVDCCGSLV---------ENEVTERLRNLIRENKDDR--QMRVVLLASGGH 230
Query: 230 FAGAVVSHQKIPTNGNNKNKYILSLQEQSVQFLEQKTFHRYTTRRKQGGSQSANDNAKGK 289
FAG V + + + + KTFHR K G QS D +
Sbjct: 231 FAGTVFNGKSV---------------------VAHKTFHR----AKAGKKQSTKDASGRS 265
Query: 290 ANSAGSTLRRYNEAALKADIQALLKDWEPYIAKCDNIFIRANSVTDRKIFL-DNTCISKT 348
+SAG++LRRYNE ALK DIQ LL W+PY +F+ A S + + +F S
Sbjct: 266 IHSAGASLRRYNELALKKDIQELLASWKPYFDGAACVFVHAPSSSRQLLFNGGKPYFSSQ 325
Query: 349 DVKLKSFPFTTMRPSSNELRRAWVQLTYLSITDKPQPKVKKLQTDHSKNKPRKLTNSPTP 408
+ +++ PFT RP+ E +R + QLT ++ + + N+P ++T + T
Sbjct: 326 NCAVRNVPFTIRRPTFKESQRIYNQLT----------QIAHVTEEIFVNRP-EVTKANTV 374
Query: 409 VPLKTEDEQHTEKLISFIQKSKAPLLISYIKKNNLDVNITLQPSSEYHHTPTMLHYASSH 468
V ED T + + S + +++ + N ++ +I T T LH A+
Sbjct: 375 VQTHNEDSGKTSRKEEPDETSSSNIILE--EPNRIEEDI----EDGVTGTSTALHEAAKS 428
Query: 469 GLKHMVLVLLSTLKADPTITNNVGKTAWDLASDTMVKETF-QLARYNLGESFTDWEQSHV 527
G V+ L DP + G+T + LA++ V+ TF + NL + +W + V
Sbjct: 429 GDCERVMEFLEE-GMDPCAKDERGRTPYMLANEKEVRNTFRRFMALNLEK--WNWHDAKV 485
Query: 528 SGALSAE 534
L+ E
Sbjct: 486 PSPLTKE 492
>CE26941 [R] KOG2505 Ankyrin repeat protein
Length = 618
Score = 101 bits (251), Expect = 4e-21
Identities = 83/354 (23%), Positives = 150/354 (41%), Gaps = 71/354 (20%)
Query: 222 LFMIGGGHFAGAVVSHQKIPTNGNNKNKYILSLQEQSVQFLEQKTFHRYTTRRKQGGSQS 281
+F+ GGHFA A+ + K+ QK+FHRY R KQGG QS
Sbjct: 176 IFLWNGGHFAAAMFENDKMTV---------------------QKSFHRYVARAKQGGVQS 214
Query: 282 ANDNA-KGKANSAGSTLRRYNEAALKADIQALLKDWEPYIAKCDNIFIRANSVTDRKIFL 340
+D+ KG A SAG+ LRRYNE +K +IQ+++ W+ + K +FIR + F
Sbjct: 215 QHDSGGKGAAKSAGAQLRRYNEQKMKEEIQSIMSSWKSRLQKTPLLFIRCAAYHRNIFFE 274
Query: 341 DNTCISKTDVKLKSFPFTTMRPSSNELRRAWVQLTYLS--------------ITDKPQPK 386
+ I D ++++ PF T RP+ +E+ W +L +S + +K +
Sbjct: 275 ADAGIETRDDRIRTIPFETKRPNIDEISDCWQRLQQVSEHGAESDFRAEMLEVREKRKKL 334
Query: 387 VKKL-----------------------------QTDHSKNKPRKLTNSPTPVPLKTEDEQ 417
+K+ +T H K + K T V D++
Sbjct: 335 ARKVAGKKRKDGGMQMICEWSDDDENEDISKEKKTHHIKVRTIKKPEE-TVVQWPRLDDE 393
Query: 418 HTEKLISFIQKSKAPLLISYIKKNNLDV----NITLQPSSEYHHTPTMLHYASSHGLKHM 473
+K +++++ L ++ N DV N L+ + + T LH ++++ +
Sbjct: 394 WRQKTYNYVRQDSVEALKEHLASLNEDVTSEANDYLRNAKIPPNRSTFLHVSAANDARKC 453
Query: 474 VLVLLSTLKADPTITNNVGKTAWDLASDTMVKETFQLARYNLGESFTDWEQSHV 527
+ L + D + + G + ++++ VK F R E+ +W ++H+
Sbjct: 454 LKYFLEEVNCDSSTKDGAGLPPYSSSANSDVKSIFIDYRVK-NETAGNWARTHI 506
>Hs8922413 [R] KOG2505 Ankyrin repeat protein
Length = 342
Score = 77.4 bits (189), Expect = 6e-14
Identities = 73/282 (25%), Positives = 117/282 (40%), Gaps = 66/282 (23%)
Query: 58 CASCGINAFPNDNSDPRYHFKTDLHKFNIKRRVYGLSPVDEQEFRQLIKSKETATAXXXX 117
C++C F N + + R H+K D H+FN+K+R+ + +F K+++T
Sbjct: 74 CSTCD-QTFQN-HQEQREHYKLDWHRFNLKQRLKDKPLLSALDFE-----KQSSTGDLS- 125
Query: 118 XXXXXXXXXXXXXXXXXXXSTRGGEQLTAILEHELQDLMINDNQTGPVSHLNTQSPLIFM 177
S G E + E +LQ L D + L+ + P +
Sbjct: 126 -------------------SISGSEDSDSASEEDLQTL---DRERATFEKLS-RPPGFYP 162
Query: 178 HSAELSGPR--IFGAYKVLFNA-----EELKCPLKSIHHWKNQDKTEHFSVLFMIGGGHF 230
H + AY+ + EE + L+++ Q + V+ M GHF
Sbjct: 163 HRVLFQNAQGQFLYAYRCVLGPHQDPPEEAELLLQNL-----QSRGPRDCVVLMAAAGHF 217
Query: 231 AGAVVSHQKIPTNGNNKNKYILSLQEQSVQFLEQKTFHRYTTRRKQGGSQSANDNAKGKA 290
AGA+ +++ T+ KTFHRYT R K+G +Q D G +
Sbjct: 218 AGAIFQGREVVTH---------------------KTFHRYTVRAKRGTAQGLRDARGGPS 256
Query: 291 NSAGSTLRRYNEAALKADIQALL--KDWEPYIAKCDNIFIRA 330
+SAG+ LRRYNEA L D++ LL W + + I +RA
Sbjct: 257 HSAGANLRRYNEATLYKDVRDLLAGPSWAKALEEAGTILLRA 298
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.130 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,097,471
Number of Sequences: 60738
Number of extensions: 1329870
Number of successful extensions: 2978
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2954
Number of HSP's gapped (non-prelim): 8
length of query: 621
length of database: 30,389,216
effective HSP length: 112
effective length of query: 509
effective length of database: 23,586,560
effective search space: 12005559040
effective search space used: 12005559040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)