ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3186 check: MH T KOG0032 Signal transduction mechanisms Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3186 1122745 1124382 546
(546 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 545 e-155
SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 348 9e-96
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 325 1e-88
SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinas... 289 9e-78
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 196 1e-49
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 192 8e-49
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 186 8e-47
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 181 3e-45
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 178 2e-44
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 172 2e-42
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 169 8e-42
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 167 3e-41
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 166 6e-41
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 165 1e-40
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 162 1e-39
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 162 1e-39
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 162 1e-39
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 162 1e-39
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 162 1e-39
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 162 1e-39
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 162 1e-39
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 162 1e-39
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 162 1e-39
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 162 1e-39
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 159 8e-39
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 159 1e-38
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 158 2e-38
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 157 4e-38
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 157 5e-38
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 155 1e-37
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 155 2e-37
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 153 6e-37
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 153 6e-37
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 152 2e-36
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 151 3e-36
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 150 5e-36
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 149 1e-35
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 149 1e-35
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 148 2e-35
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 147 3e-35
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 147 3e-35
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 147 3e-35
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 147 3e-35
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 147 4e-35
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 147 4e-35
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 147 5e-35
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 147 5e-35
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 146 7e-35
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 146 9e-35
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 146 9e-35
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 144 4e-34
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 144 4e-34
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 143 6e-34
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 142 1e-33
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 142 2e-33
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 142 2e-33
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 142 2e-33
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 141 2e-33
At1g01140 [T] KOG0583 Serine/threonine protein kinase 141 2e-33
HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2 141 3e-33
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 140 4e-33
Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2 140 4e-33
Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2 140 4e-33
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 140 4e-33
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 140 6e-33
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 140 6e-33
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 140 6e-33
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 140 6e-33
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 139 8e-33
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 139 8e-33
At2g26980 [T] KOG0583 Serine/threonine protein kinase 139 8e-33
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 139 1e-32
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 139 1e-32
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 139 1e-32
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 139 1e-32
7295638 [T] KOG0603 Ribosomal protein S6 kinase 139 1e-32
At5g10930 [T] KOG0583 Serine/threonine protein kinase 139 1e-32
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 138 2e-32
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 137 3e-32
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 137 3e-32
At1g30270 [T] KOG0583 Serine/threonine protein kinase 137 4e-32
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 137 5e-32
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 137 5e-32
7302464 [R] KOG0586 Serine/threonine protein kinase 137 5e-32
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 136 7e-32
At5g39440 [T] KOG0583 Serine/threonine protein kinase 136 7e-32
YDR477w [T] KOG0583 Serine/threonine protein kinase 136 9e-32
At2g30360 [T] KOG0583 Serine/threonine protein kinase 136 9e-32
At5g25110 [T] KOG0583 Serine/threonine protein kinase 135 1e-31
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 135 1e-31
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 134 3e-31
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 134 4e-31
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 134 4e-31
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 133 6e-31
At5g01820 [T] KOG0583 Serine/threonine protein kinase 133 6e-31
At4g30960 [T] KOG0583 Serine/threonine protein kinase 133 6e-31
At2g38490 [T] KOG0583 Serine/threonine protein kinase 133 6e-31
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 1e-30
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 1e-30
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 132 1e-30
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 132 1e-30
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 1e-30
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 2e-30
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 2e-30
At3g01090 [T] KOG0583 Serine/threonine protein kinase 132 2e-30
7299438 [R] KOG0586 Serine/threonine protein kinase 131 2e-30
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 131 3e-30
CE28218 [D] KOG0588 Serine/threonine protein kinase 130 4e-30
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 130 4e-30
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 130 5e-30
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 130 5e-30
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 130 7e-30
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 129 9e-30
CE27768 [R] KOG0586 Serine/threonine protein kinase 129 1e-29
CE23838 [R] KOG0586 Serine/threonine protein kinase 129 1e-29
At3g29160 [T] KOG0583 Serine/threonine protein kinase 129 1e-29
At2g25090 [T] KOG0583 Serine/threonine protein kinase 129 1e-29
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 128 3e-29
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 3e-29
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 127 4e-29
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 127 6e-29
At3g23000 [T] KOG0583 Serine/threonine protein kinase 127 6e-29
7299437 [R] KOG0586 Serine/threonine protein kinase 127 6e-29
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 126 7e-29
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 126 7e-29
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 125 1e-28
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 1e-28
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 1e-28
At4g18700 [T] KOG0583 Serine/threonine protein kinase 125 1e-28
CE17284 [T] KOG0583 Serine/threonine protein kinase 125 2e-28
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 2e-28
7290249 [R] KOG0586 Serine/threonine protein kinase 125 2e-28
At5g01810 [T] KOG0583 Serine/threonine protein kinase 125 2e-28
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 2e-28
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 2e-28
7294217 [D] KOG0588 Serine/threonine protein kinase 124 3e-28
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 124 5e-28
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 5e-28
At4g24400 [T] KOG0583 Serine/threonine protein kinase 123 6e-28
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 123 8e-28
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 123 8e-28
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 122 1e-27
At5g45820 [T] KOG0583 Serine/threonine protein kinase 122 1e-27
At4g14580 [T] KOG0583 Serine/threonine protein kinase 122 1e-27
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 1e-27
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 122 2e-27
CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2 122 2e-27
YKL101w [D] KOG0588 Serine/threonine protein kinase 121 2e-27
At2g45490 [D] KOG0580 Serine/threonine protein kinase 121 2e-27
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 121 3e-27
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 5e-27
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 5e-27
At5g45810 [T] KOG0583 Serine/threonine protein kinase 120 7e-27
7290150 [T] KOG0583 Serine/threonine protein kinase 119 9e-27
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 119 1e-26
CE28643 [T] KOG0583 Serine/threonine protein kinase 119 1e-26
CE07458 [T] KOG0583 Serine/threonine protein kinase 119 1e-26
YLR096w [T] KOG0583 Serine/threonine protein kinase 118 2e-26
At5g35410 [T] KOG0583 Serine/threonine protein kinase 118 3e-26
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 117 3e-26
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 117 4e-26
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 117 4e-26
7300106 [T] KOG0690 Serine/threonine protein kinase 117 4e-26
CE24761 [D] KOG0580 Serine/threonine protein kinase 117 6e-26
YPL209c [D] KOG0580 Serine/threonine protein kinase 116 1e-25
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 116 1e-25
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 116 1e-25
Hs21361101 [T] KOG0607 MAP kinase-interacting kinase and related... 115 1e-25
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 115 2e-25
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 114 3e-25
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 3e-25
At1g29230 [T] KOG0583 Serine/threonine protein kinase 114 3e-25
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 114 4e-25
YDR507c [D] KOG0588 Serine/threonine protein kinase 114 5e-25
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 114 5e-25
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 114 5e-25
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 114 5e-25
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 113 6e-25
CE21025 [D] KOG0580 Serine/threonine protein kinase 113 6e-25
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 113 8e-25
CE00847 [T] KOG0583 Serine/threonine protein kinase 113 8e-25
7303211 [T] KOG4717 Serine/threonine protein kinase 113 8e-25
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 112 1e-24
7302570 [R] KOG0586 Serine/threonine protein kinase 112 1e-24
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 112 1e-24
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 112 1e-24
At2g34180 [T] KOG0583 Serine/threonine protein kinase 112 1e-24
YCL024w [T] KOG0583 Serine/threonine protein kinase 112 2e-24
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 112 2e-24
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 111 2e-24
7299536 [D] KOG0580 Serine/threonine protein kinase 111 2e-24
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 111 3e-24
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 3e-24
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 3e-24
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 3e-24
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 110 4e-24
At4g32830 [D] KOG0580 Serine/threonine protein kinase 110 4e-24
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 110 5e-24
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 110 5e-24
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 110 5e-24
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 110 5e-24
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 110 5e-24
At5g58380 [T] KOG0583 Serine/threonine protein kinase 110 5e-24
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 110 7e-24
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 110 7e-24
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 110 7e-24
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 110 7e-24
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 110 7e-24
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 110 7e-24
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 109 9e-24
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 109 9e-24
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 109 9e-24
At1g48260 [T] KOG0583 Serine/threonine protein kinase 109 9e-24
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 109 1e-23
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 109 1e-23
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 108 2e-23
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 108 2e-23
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 108 2e-23
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 108 3e-23
CE27131_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 108 3e-23
At5g07070 [T] KOG0583 Serine/threonine protein kinase 107 4e-23
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 4e-23
CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit 107 5e-23
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 107 5e-23
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 107 5e-23
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 107 5e-23
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 107 6e-23
YDR122w [T] KOG0583 Serine/threonine protein kinase 107 6e-23
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 107 6e-23
At5g57630 [T] KOG0583 Serine/threonine protein kinase 107 6e-23
At2g25880 [D] KOG0580 Serine/threonine protein kinase 107 6e-23
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 106 1e-22
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 106 1e-22
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 106 1e-22
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 106 1e-22
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 105 1e-22
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 105 1e-22
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 105 1e-22
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 105 1e-22
At3g17510 [T] KOG0583 Serine/threonine protein kinase 105 2e-22
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 105 2e-22
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 105 2e-22
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 105 2e-22
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 104 3e-22
YPL141c [T] KOG0583 Serine/threonine protein kinase 104 4e-22
At4g40010 [T] KOG0583 Serine/threonine protein kinase 104 4e-22
At1g78290 [T] KOG0583 Serine/threonine protein kinase 104 4e-22
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 104 4e-22
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 103 5e-22
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 7e-22
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 103 7e-22
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 103 7e-22
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 103 7e-22
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 103 7e-22
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 103 7e-22
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 103 7e-22
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 103 7e-22
YOR233w [T] KOG0583 Serine/threonine protein kinase 103 9e-22
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 103 9e-22
CE28479 [T] KOG0583 Serine/threonine protein kinase 103 9e-22
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 103 9e-22
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 102 1e-21
7297776 [D] KOG0580 Serine/threonine protein kinase 102 1e-21
Hs5902140_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 102 1e-21
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 102 2e-21
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 102 2e-21
CE29298 [T] KOG0690 Serine/threonine protein kinase 102 2e-21
CE18646 [T] KOG0690 Serine/threonine protein kinase 102 2e-21
7297080 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
CE18454 [T] KOG4717 Serine/threonine protein kinase 101 3e-21
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 101 3e-21
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 101 3e-21
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 101 3e-21
CE15612 [T] KOG0690 Serine/threonine protein kinase 101 3e-21
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 101 3e-21
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 100 4e-21
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 4e-21
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 100 6e-21
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 100 6e-21
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 6e-21
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 100 7e-21
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 100 7e-21
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 100 7e-21
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 7e-21
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 100 1e-20
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 100 1e-20
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 100 1e-20
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 99 1e-20
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 99 1e-20
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 99 1e-20
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 99 1e-20
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 99 2e-20
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 99 2e-20
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 99 2e-20
7291710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 99 2e-20
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 99 2e-20
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 99 2e-20
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 99 2e-20
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 99 2e-20
At5g09890 [R] KOG0605 NDR and related serine/threonine kinases 99 2e-20
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 98 3e-20
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 98 3e-20
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 98 3e-20
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 98 4e-20
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 98 4e-20
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 98 4e-20
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 4e-20
At2g23030 [T] KOG0583 Serine/threonine protein kinase 98 4e-20
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 97 5e-20
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 97 5e-20
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 97 5e-20
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 97 5e-20
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 97 6e-20
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 97 6e-20
CE15235 [R] KOG0589 Serine/threonine protein kinase 97 6e-20
At1g10940 [T] KOG0583 Serine/threonine protein kinase 97 6e-20
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 97 6e-20
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 97 6e-20
YPL150w [T] KOG0583 Serine/threonine protein kinase 97 8e-20
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 97 8e-20
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 97 8e-20
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 97 8e-20
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 97 8e-20
At4g33950 [T] KOG0583 Serine/threonine protein kinase 97 8e-20
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 97 8e-20
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 96 1e-19
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 96 2e-19
CE16081 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 96 2e-19
At3g50500 [T] KOG0583 Serine/threonine protein kinase 95 2e-19
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 95 3e-19
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 95 3e-19
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 95 3e-19
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 95 3e-19
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 94 4e-19
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 94 4e-19
At5g08590 [T] KOG0583 Serine/threonine protein kinase 94 4e-19
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 94 5e-19
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 94 5e-19
At1g60940 [T] KOG0583 Serine/threonine protein kinase 94 5e-19
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 94 5e-19
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 94 7e-19
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 94 7e-19
Hs16950619 [Z] KOG0613 Projectin/twitchin and related proteins 94 7e-19
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 94 7e-19
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 94 7e-19
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 94 7e-19
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 94 7e-19
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 94 7e-19
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 93 9e-19
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 93 9e-19
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 93 9e-19
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 93 1e-18
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 93 1e-18
CE29092 [T] KOG0694 Serine/threonine protein kinase 93 1e-18
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 92 2e-18
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 92 2e-18
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 92 2e-18
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 92 3e-18
At5g63650 [T] KOG0583 Serine/threonine protein kinase 92 3e-18
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 92 3e-18
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 91 3e-18
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 91 3e-18
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 91 4e-18
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 91 4e-18
CE05274 [T] KOG0690 Serine/threonine protein kinase 91 4e-18
At5g66880 [T] KOG0583 Serine/threonine protein kinase 91 4e-18
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 91 4e-18
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 91 4e-18
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 91 6e-18
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 91 6e-18
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 91 6e-18
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 91 6e-18
7301734 [T] KOG0694 Serine/threonine protein kinase 91 6e-18
Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins 90 8e-18
Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins 90 8e-18
Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins 90 8e-18
Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins 90 8e-18
7299793 [T] KOG0583 Serine/threonine protein kinase 90 8e-18
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 90 8e-18
Hs4505811 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 90 1e-17
SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases 89 1e-17
7294770 [T] KOG0603 Ribosomal protein S6 kinase 89 1e-17
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 89 2e-17
Hs22068996 [T] KOG1345 Serine/threonine kinase 89 2e-17
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 89 2e-17
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 89 2e-17
Hs8923539 [R] KOG0597 Serine-threonine protein kinase FUSED 89 2e-17
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 89 2e-17
7300413 [T] KOG0583 Serine/threonine protein kinase 89 2e-17
Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 88 3e-17
7303860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 88 3e-17
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 88 4e-17
7291709 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 88 4e-17
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 87 5e-17
CE01554 [T] KOG0986 G protein-coupled receptor kinase 87 5e-17
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 87 6e-17
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 87 6e-17
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 87 6e-17
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 87 6e-17
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 87 8e-17
CE28571 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 87 8e-17
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 86 1e-16
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 86 1e-16
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 86 2e-16
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 86 2e-16
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 85 3e-16
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 85 3e-16
CE27899 [D] KOG0590 Checkpoint kinase and related serine/threoni... 85 3e-16
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 85 3e-16
CE02586 [T] KOG0696 Serine/threonine protein kinase 85 3e-16
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 84 4e-16
SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine ki... 84 7e-16
At5g55090 [T] KOG0198 MEKK and related serine/threonine protein ... 84 7e-16
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 84 7e-16
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 83 9e-16
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 83 9e-16
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 83 9e-16
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 83 9e-16
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 83 9e-16
YHR102w [T] KOG0201 Serine/threonine protein kinase 83 1e-15
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 83 1e-15
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 83 1e-15
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 82 2e-15
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 82 2e-15
7301980 [D] KOG0608 Warts/lats-like serine threonine kinases 82 2e-15
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 82 2e-15
CE17354 [T] KOG0694 Serine/threonine protein kinase 82 2e-15
CE17353 [T] KOG0694 Serine/threonine protein kinase 82 2e-15
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 82 2e-15
YAR018c [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 82 3e-15
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 82 3e-15
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 82 3e-15
7302860 [T] KOG0696 Serine/threonine protein kinase 82 3e-15
CE23001 [R] KOG0589 Serine/threonine protein kinase 81 4e-15
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 81 4e-15
At3g25250 [R] KOG0610 Putative serine/threonine protein kinase 81 5e-15
7300559 [T] KOG4279 Serine/threonine protein kinase 81 5e-15
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 80 6e-15
Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases 80 8e-15
ECU02g0510 [D] KOG0596 Dual specificity; serine/threonine and ty... 80 8e-15
At4g13000 [R] KOG0610 Putative serine/threonine protein kinase 80 8e-15
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 80 8e-15
YMR291w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 79 2e-14
HsM5454184 [T] KOG4721 Serine/threonine protein kinase contains ... 79 2e-14
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 79 2e-14
Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains l... 79 2e-14
Hs21735552 [T] KOG4721 Serine/threonine protein kinase contains ... 79 2e-14
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 79 2e-14
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 79 2e-14
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 79 2e-14
At2g30040 [T] KOG0198 MEKK and related serine/threonine protein ... 79 2e-14
Hs5174547 [T] KOG4279 Serine/threonine protein kinase 78 3e-14
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 78 3e-14
At1g07150 [T] KOG0198 MEKK and related serine/threonine protein ... 78 3e-14
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 77 5e-14
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 77 5e-14
At3g53570 [T] KOG0671 LAMMER dual specificity kinases 77 5e-14
7301213 [R] KOG0589 Serine/threonine protein kinase 77 5e-14
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 77 7e-14
Hs22042851 [T] KOG0986 G protein-coupled receptor kinase 77 7e-14
7300551 [T] KOG1027 Serine/threonine protein kinase and endoribo... 77 7e-14
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 76 1e-13
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 76 1e-13
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 76 1e-13
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 76 1e-13
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 76 1e-13
At3g20860 [R] KOG0589 Serine/threonine protein kinase 76 1e-13
7301719 [T] KOG0671 LAMMER dual specificity kinases 76 1e-13
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 75 2e-13
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 75 3e-13
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 75 3e-13
At5g28290 [R] KOG0589 Serine/threonine protein kinase 75 3e-13
7302861 [T] KOG0696 Serine/threonine protein kinase 75 3e-13
7300224 [T] KOG0201 Serine/threonine protein kinase 75 3e-13
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 74 6e-13
At3g53930 [OUT] KOG0595 Serine/threonine-protein kinase involved... 74 6e-13
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 74 7e-13
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 74 7e-13
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 73 1e-12
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 73 1e-12
7303915 [T] KOG0694 Serine/threonine protein kinase 73 1e-12
7303914 [T] KOG0694 Serine/threonine protein kinase 73 1e-12
CE18699 [T] KOG0694 Serine/threonine protein kinase 73 1e-12
At4g24740 [T] KOG0671 LAMMER dual specificity kinases 73 1e-12
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 72 2e-12
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 72 2e-12
Hs22057563 [D] KOG0615 Serine/threonine protein kinase Chk2 and ... 72 2e-12
Hs10190706 [T] KOG0671 LAMMER dual specificity kinases 72 2e-12
Hs4502883_2 [T] KOG0671 LAMMER dual specificity kinases 72 2e-12
At4g31170 [T] KOG0192 Tyrosine kinase specific for activated (GT... 71 4e-12
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 71 5e-12
YHR082c [T] KOG0583 Serine/threonine protein kinase 70 6e-12
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 70 8e-12
At3g04810 [R] KOG0589 Serine/threonine protein kinase 70 8e-12
Hs4502885_2 [T] KOG0671 LAMMER dual specificity kinases 70 1e-11
>YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 545 bits (1404), Expect = e-155
Identities = 284/467 (60%), Positives = 342/467 (72%), Gaps = 29/467 (6%)
Query: 94 DESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIA 153
D+S+D E PE F EQ EL Y LI KIGEGAFSKV+R IP+ N ++ +
Sbjct: 137 DDSTDDDNMEDEIPEKSFLEQKELIGYKLINKIGEGAFSKVFRAIPA----KNSSNEFLT 192
Query: 154 QQYKEVAIKVIIKQQLPNTN----KKGDEKNG-KTSTAEQVLKEIAIHKIVSSG-ENIVS 207
+ YK VAIKVI K L + N KK K+ KTS+ +QVLKE+A+HK VS+G IV+
Sbjct: 193 KNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVA 252
Query: 208 FIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHR 267
FIDFQE++ YYYIIQELL GGEIFGEIV+ TYFSEDLSRHVI+QLA AVK+MH LG+VHR
Sbjct: 253 FIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHR 312
Query: 268 DIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI 327
DIKPENLLFEPI+F + KPKLR SDDP TK DEG+F P +VKLADFGLSKQI
Sbjct: 313 DIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQI 372
Query: 328 YQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKI 387
+ NTKTPCGTVGYTAPEVVKDE YSM+VDMWG+GCVLYT+LCGFPPF+DEKID LTEKI
Sbjct: 373 FSKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKI 432
Query: 388 SRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNA 447
SRGEYTFL+PWWD+IS GAKN V KLLE++P+KRY +Q L DPWLN++DCLP S+
Sbjct: 433 SRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWLNTFDCLPKEGESSQ 492
Query: 448 PSTG-EKRRHSHKHSRKAYKKNASLLYSPAAVAMRDAFDVSNAVQRIEDDKRMTPGPKXX 506
G +RRH HK + +++++SLL+SPAAVAMRDAFD+ NAV+R E+D+ T G
Sbjct: 493 KKAGTSERRHPHKKQFQLFQRDSSLLFSPAAVAMRDAFDIGNAVKRTEEDRMGTRG---- 548
Query: 507 XXXXXLGVLAEDAEAEIQY----------REPFTLKLDSSSIIKRRR 543
LG LAED E E Y + F L LD+S+I++RR+
Sbjct: 549 ----GLGSLAEDEELEDSYSGAQGDEQLEQNMFQLTLDTSTILQRRK 591
>SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 580
Score = 348 bits (894), Expect = 9e-96
Identities = 185/414 (44%), Positives = 266/414 (63%), Gaps = 24/414 (5%)
Query: 90 ENTYDESSDATTTP---QEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSN 146
E YD++ +A +E FP L+ YTL+QK+G+GAFS VY+ I + +
Sbjct: 91 EKEYDKAIEALVAKAIVEEHSGQQFPVYKGLEQYTLLQKMGDGAFSNVYKAIHNRTG--- 147
Query: 147 GASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIV 206
++VAIKV+ + Q PNT+ + D + + + +LKE+ I + V NI+
Sbjct: 148 ----------EKVAIKVVQRAQ-PNTDPR-DPRKRQGVESHNILKEVQIMRRVKH-PNII 194
Query: 207 SFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQ-LGIV 265
++F ++ +YYY++ EL GGE+F +IV+ TYFSEDLSRHVI Q+A+A++Y+H+ G+V
Sbjct: 195 QLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVITQVAHAIRYLHEDCGVV 254
Query: 266 HRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSK 325
HRDIKPENLLF+ IDF+P+ K R+ DDP K+DEG F P ++LADFGLSK
Sbjct: 255 HRDIKPENLLFDSIDFVPSRVRKYRAGDDPD-KVDEGEFIPGVGAGTIGRIRLADFGLSK 313
Query: 326 QIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTE 385
++ ++T+TPCGT+GYTAPE+V+DERYS VDMW +GCVLYT+LCGFPPF+DE I +LT+
Sbjct: 314 VVWDSHTQTPCGTMGYTAPEIVRDERYSKGVDMWALGCVLYTILCGFPPFYDESISLLTK 373
Query: 386 KISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHS 445
K+SRGEY+FL PWWD IS AK+ + LL VDP RY Q L PW+ S P+ +
Sbjct: 374 KVSRGEYSFLSPWWDDISKSAKDLISHLLTVDPESRYDIHQFLAHPWI-SGSREPTFPAT 432
Query: 446 NAPSTGEKRRHSHKHSRKAYKKNA--SLLYSPAAVAMRDAFDVSNAVQRIEDDK 497
+AP+T ++ + A S +P ++R+ F++S A R+E +K
Sbjct: 433 DAPNTAQRENPFTYDFLEPEDVAAAGSAARTPGVNSLREVFNISYAAHRMEQEK 486
>YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 512
Score = 325 bits (833), Expect = 1e-88
Identities = 190/462 (41%), Positives = 254/462 (54%), Gaps = 57/462 (12%)
Query: 94 DESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIA 153
DE+S+ +T +PEQ EL +Y L+ KIGEGAFS+V++ + +
Sbjct: 96 DETSNKSTDYSSSNHQ-YPEQLELHNYKLLNKIGEGAFSRVFKAV-----------GINT 143
Query: 154 QQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGE-NIVSFIDFQ 212
VAIK IIK+ + + + S+ ++VL E+AIHK+VS + FI FQ
Sbjct: 144 DDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKVLNEVAIHKLVSKNNPHCTKFIAFQ 203
Query: 213 ESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPE 272
ES YYY++ EL+ GGEIF IV+ T FSEDL+RHVI Q+A A+K+MH +GIVHRD+KPE
Sbjct: 204 ESANYYYLVTELVTGGEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPE 263
Query: 273 NLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT 332
NLLFEPI F D K DE F +VKL DFGL+K++
Sbjct: 264 NLLFEPIPFY--------GLDGDMQKEDE--FTLGVGGGGIGLVKLMDFGLAKKLRNNTA 313
Query: 333 KTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEY 392
KTPCGT+ Y A EV +RYSM+VDMW +GCVL+T+LCG+PPF+++ L +KISRG+Y
Sbjct: 314 KTPCGTIEYVASEVFTSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDY 373
Query: 393 TFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGE 452
FL PWWD IS GAKN V LLEVDP KRY + L DPWLNSYDCL
Sbjct: 374 EFLAPWWDNISSGAKNAVTHLLEVDPNKRYDIDDFLNDPWLNSYDCL------------- 420
Query: 453 KRRHSHKHSRKAYKKNASLLYSPAAVAMRDAFD----VSNAVQRIEDDKRMTPGPKXXXX 508
K + S Y+ + D+FD + + +K+
Sbjct: 421 -------------KDSNSNSYASVQSILNDSFDERAETLHCALSCQSEKQDDTEFSRSES 467
Query: 509 XXXLGVLAEDAEAEIQY----REPFTLKLDSSSIIKRRRNNV 546
+ + ED + +E FTL L +SSI +RR+N +
Sbjct: 468 SEYIFMTEEDRNLRGSWIGEPKECFTLDLATSSIYRRRKNKI 509
>SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 504
Score = 289 bits (739), Expect = 9e-78
Identities = 149/325 (45%), Positives = 207/325 (62%), Gaps = 29/325 (8%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
L+ Y LI+ +G+GAFS+VY+ A S+ +++ VA+KVI K ++ ++G
Sbjct: 62 LEKYQLIENLGDGAFSQVYK-----------AYSIDRKEH--VAVKVIRKYEMNKKQRQG 108
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
V KE+ I + V +N+V+ DF E+E +Y+++ EL GGE+F +IV
Sbjct: 109 ------------VFKEVNIMRRVKH-KNVVNLFDFVETEDFYHLVMELAEGGELFHQIVN 155
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQL-GIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDP 295
+TYFSE+L+RH+I Q+A AVK++H + GIVHRDIKPENLLF+PI+++P+ S +
Sbjct: 156 FTYFSENLARHIIIQVAEAVKHLHDVCGIVHRDIKPENLLFQPIEYLPSQNYTPPSLEP- 214
Query: 296 STKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQ 355
KLDEG+F + +ADFG SK ++ + T TPCGTVGY APE+V DE YS
Sbjct: 215 -NKLDEGMFLEGIGAGGIGRILIADFGFSKVVWNSKTATPCGTVGYAAPEIVNDELYSKN 273
Query: 356 VDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLE 415
VDMW +GCVL+T+LCGFPPFFDE I L K+ GE+ FL PWWD ISD AK+ + LL
Sbjct: 274 VDMWAMGCVLHTMLCGFPPFFDENIKDLASKVVNGEFEFLSPWWDDISDSAKDLITHLLT 333
Query: 416 VDPAKRYTSEQLLQDPWLNSYDCLP 440
VDP +RY Q Q PW+ +P
Sbjct: 334 VDPRERYDIHQFFQHPWIKGESKMP 358
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 196 bits (497), Expect = 1e-49
Identities = 131/399 (32%), Positives = 207/399 (51%), Gaps = 73/399 (18%)
Query: 95 ESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQ 154
E+ +++++ +++ ED+ K + + +G GAFS+V V+A+
Sbjct: 4 ENGESSSSWKKQAEDI------KKIFEFKETLGTGAFSEV----------------VLAE 41
Query: 155 QY---KEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDF 211
+ K A+K I K+ L GK S+ E EIA+ + + ENIV+ D
Sbjct: 42 EKATGKLFAVKCIPKKAL----------KGKESSIEN---EIAVLRKIKH-ENIVALEDI 87
Query: 212 QESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKP 271
ES + Y++ +L++GGE+F IV+ +++E + +IRQ+ +AV Y+H++GIVHRD+KP
Sbjct: 88 YESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKP 147
Query: 272 ENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN 331
ENLL+ S D +K + ++DFGLSK + +
Sbjct: 148 ENLLYY--------------SQDEESK-----------------IMISDFGLSKMEGKGD 176
Query: 332 T-KTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRG 390
T CGT GY APEV+ + YS VD W +G + Y +LCG+PPF+DE L E+I +
Sbjct: 177 VMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKA 236
Query: 391 EYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPST 450
EY F P+WD ISD AK+ +R L+E DP KRYT EQ + PW+ L H + S
Sbjct: 237 EYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESV-SA 295
Query: 451 GEKRRHSHKHSRKAYKKNASLLYSPAAVAMRDAFDVSNA 489
++ + R+A+ A + + + + + D SNA
Sbjct: 296 QIRKNFAKSKWRQAFNATAVVRHM-RKLHLGSSLDSSNA 333
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 192 bits (489), Expect = 8e-49
Identities = 126/352 (35%), Positives = 177/352 (49%), Gaps = 62/352 (17%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y +G GAFS+V + K VAIK I K+ L K+G +
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQ-------------KLVAIKCIAKEALEG--KEGSME 64
Query: 180 NGKTSTAEQVLKEIAI-HKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
N EIA+ HKI NIV+ D ES + Y+I +L++GGE+F IV+
Sbjct: 65 N-----------EIAVLHKI--KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKG 111
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
+++E + +I Q+ +AVKY+H LGIVHRD+KPENLL+ +D
Sbjct: 112 FYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLD------------------ 153
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVD 357
+ ++DFGLSK + T CGT GY APEV+ + YS VD
Sbjct: 154 -------------EDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVD 200
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
W +G + Y +LCG+PPF+DE L E+I + EY F P+WD ISD AK+ +R L+E D
Sbjct: 201 CWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKD 260
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAYKKNA 469
P KR+T EQ LQ PW+ L H + S K+ + ++A+ A
Sbjct: 261 PEKRFTCEQALQHPWIAGDTALDKNIHQSV-SEQIKKNFAKSKWKQAFNATA 311
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 186 bits (472), Expect = 8e-47
Identities = 115/325 (35%), Positives = 165/325 (50%), Gaps = 65/325 (20%)
Query: 118 KDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGD 177
K + ++ +G GAFS+V+ ++KQ+L T K
Sbjct: 21 KTFIFMEVLGSGAFSEVF----------------------------LVKQRL--TGKLFA 50
Query: 178 EKNGKTSTA---EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEI 234
K K S A + EIA+ K + ENIV+ D ES +YY++ +L++GGE+F I
Sbjct: 51 LKCIKKSPAFRDSSLENEIAVLKKIKH-ENIVTLEDIYESTTHYYLVMQLVSGGELFDRI 109
Query: 235 VKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDD 294
++ ++E + VI+Q+ +AVKY+H+ GIVHRD+KPENLL+ P K
Sbjct: 110 LERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLY----LTPEENSK------ 159
Query: 295 PSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSM 354
+ + DFGLSK T CGT GY APEV+ + YS
Sbjct: 160 ---------------------IMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSK 198
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
VD W +G + Y +LCG+PPF++E L EKI G Y F P+WD IS+ AK+ + LL
Sbjct: 199 AVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLL 258
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCL 439
E DP +RYT E+ L PW++ L
Sbjct: 259 EKDPNERYTCEKALSHPWIDGNTAL 283
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 181 bits (459), Expect = 3e-45
Identities = 116/360 (32%), Positives = 177/360 (48%), Gaps = 58/360 (16%)
Query: 112 PEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPN 171
P T + Y +G GAFSKV+ + S Q Y A+K I K+ L
Sbjct: 14 PNATIREKYDFRDVLGTGAFSKVFLA---------ESKSDAGQMY---AVKCIDKKAL-- 59
Query: 172 TNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIF 231
GK + E +K + K+ + NIV D + +++ Y++ EL+ GGE+F
Sbjct: 60 --------KGKEESLENEIK--VLRKLRHN--NIVQLFDTYDEKQFVYLVMELVTGGELF 107
Query: 232 GEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRS 291
IV ++E + ++IRQ+ AV +MH G+VHRD+KPENLL+
Sbjct: 108 DRIVAKGSYTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYY-------------- 153
Query: 292 SDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDER 351
+ D +K + ++DFGLSK T CGT GY APEV++ +
Sbjct: 154 NQDEDSK-----------------IMISDFGLSKTEDSGVMATACGTPGYVAPEVLQQKP 196
Query: 352 YSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVR 411
Y VD+W +G + Y +LCG+PPF+DE L +I +GEY F P+WDQISD AK+ +
Sbjct: 197 YGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKDFIT 256
Query: 412 KLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAYKKNASL 471
L+ DP R+T + L PW++ H + K+ + ++ +KAY A++
Sbjct: 257 HLMCCDPEARFTCQDALSHPWISGNTAYTHDIHGTV-AVHLKKSLAKRNWKKAYNAAAAI 315
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 178 bits (452), Expect = 2e-44
Identities = 105/267 (39%), Positives = 148/267 (55%), Gaps = 42/267 (15%)
Query: 178 EKNGKTSTAEQVLKEIAIHKIVS---------SGENIVSFIDFQESEKYYYIIQELLAGG 228
+K + A +VLK+ KIV S NI+ + E+ ++ EL+ GG
Sbjct: 65 QKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGG 124
Query: 229 EIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPK 288
E+F IV+ Y+SE + ++Q+ AV Y+H+ GIVHRD+KPENLL+ P P
Sbjct: 125 ELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLY------ATPAP- 177
Query: 289 LRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-YQTNTKTPCGTVGYTAPEVV 347
D P +K+ADFGLSK + +Q KT CGT GY APE++
Sbjct: 178 ----DAP--------------------LKIADFGLSKIVEHQVLMKTVCGTPGYCAPEIL 213
Query: 348 KDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKID-VLTEKISRGEYTFLRPWWDQISDGA 406
+ Y +VDMW VG + Y +LCGF PF+DE+ D + +I EY F+ PWWD++S A
Sbjct: 214 RGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNA 273
Query: 407 KNCVRKLLEVDPAKRYTSEQLLQDPWL 433
K+ VRKL+ +DP KR T+ Q LQ PW+
Sbjct: 274 KDLVRKLIVLDPKKRLTTFQALQHPWV 300
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 172 bits (435), Expect = 2e-42
Identities = 114/354 (32%), Positives = 176/354 (49%), Gaps = 59/354 (16%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L +G GAFS+V + S S G + A+K+I K+ L KG E+
Sbjct: 31 YNLHGLLGTGAFSEVRL---AESKDSPG---------EHFAVKIIDKKAL-----KGKEE 73
Query: 180 NGKTSTAEQVLKEIAIHKIVS--------SGENIVSFIDFQESEKYYYIIQELLAGGEIF 231
+ + +VL+ + + + NIV ++ E + Y++ EL+ GGE+F
Sbjct: 74 SLENEI--RVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELF 131
Query: 232 GEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRS 291
IV+ ++E + H+IRQ+ AV YMH+ G+VHRD+KPENLL+ S
Sbjct: 132 DRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYY-------------S 178
Query: 292 SDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDER 351
DD S + ++DFGLSK T CGT GY APEV+ +
Sbjct: 179 PDDDSK------------------IMISDFGLSKMEDSGIMATACGTPGYVAPEVLAQKP 220
Query: 352 YSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVR 411
Y VD+W +G + Y +LCG+PPF+DE L +I +G++ F P+WD+IS+ AK+ ++
Sbjct: 221 YGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIK 280
Query: 412 KLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAY 465
L+ V KRYT +Q L W++ + H S K+ + ++AY
Sbjct: 281 NLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTV-SEQLKKNFAKSRWKQAY 333
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 169 bits (429), Expect = 8e-42
Identities = 125/385 (32%), Positives = 182/385 (46%), Gaps = 74/385 (19%)
Query: 94 DESSDATTTPQEEPEDVFPEQTE--------------LKDYTLIQKIGEGAFSKVYRGIP 139
D+ + P+ PE+ PE+ K Y + IG+G F+ V
Sbjct: 244 DQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVV----- 298
Query: 140 STSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIV 199
C + + Q Y A+K+I K +L KG E + V EI I + +
Sbjct: 299 --KECRHRETR---QAY---AMKIIDKSRL-----KGKE--------DMVDSEILIIQSL 337
Query: 200 SSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYM 259
S NIV + E++ Y+I E + GG++F I++ F E + +I L A+ +M
Sbjct: 338 SH-PNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHM 396
Query: 260 HQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLA 319
H IVHRD+KPENLL ++ ++D ST L KLA
Sbjct: 397 HDKSIVHRDLKPENLL-------------VQRNEDKSTTL-----------------KLA 426
Query: 320 DFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFF--D 377
DFGL+K + + T CGT Y APE++ ++ Y ++VDMW G +LY +LCGFPPF +
Sbjct: 427 DFGLAKHVVRP-IFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPE 485
Query: 378 EKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYD 437
D L I G + FL P+WD ISD AK+ V +LL VDP KRYT+ Q+LQ PW+ +
Sbjct: 486 RDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAG 545
Query: 438 CLPSADHSNAPSTGEKRRHSHKHSR 462
+ S + +H R
Sbjct: 546 KTNTVKRQKQVSPSSEGHFRSQHKR 570
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 167 bits (424), Expect = 3e-41
Identities = 108/329 (32%), Positives = 167/329 (49%), Gaps = 59/329 (17%)
Query: 118 KDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGD 177
++Y L +++G+GAFS V R + V+A Q E A K+I NT K
Sbjct: 11 EEYQLFEELGKGAFSVVRRCV-----------KVLAGQ--EYAAKII------NTKKLSA 51
Query: 178 EKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKY 237
+ K ++ + + NIV D E ++Y+I +L+ GGE+F +IV
Sbjct: 52 RDHQKLEREARICRLL-------KHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAR 104
Query: 238 TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPST 297
Y+SE + H I+Q+ AV + HQ+G+VHRD+KPENLL KL+ +
Sbjct: 105 EYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLAS---------KLKGA----- 150
Query: 298 KLDEGVFRPXXXXXXXXVVKLADFGLSKQIY--QTNTKTPCGTVGYTAPEVVKDERYSMQ 355
VKLADFGL+ ++ Q GT GY +PEV++ + Y
Sbjct: 151 -----------------AVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKP 193
Query: 356 VDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLE 415
VD+W G +LY +L G+PPF+DE L ++I G Y F P WD ++ AK+ + K+L
Sbjct: 194 VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLT 253
Query: 416 VDPAKRYTSEQLLQDPWLNSYDCLPSADH 444
++P+KR T+ + L+ PW++ + S H
Sbjct: 254 INPSKRITAAEALKHPWISHRSTVASCMH 282
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 166 bits (421), Expect = 6e-41
Identities = 109/352 (30%), Positives = 180/352 (50%), Gaps = 67/352 (19%)
Query: 94 DESSDATTTPQEEPEDVFPEQTEL--------KDYTLIQKIGEGAFSKVYRGIPSTSNCS 145
D+ S+ ++P++ ED + + K Y + +G G F V + N
Sbjct: 3 DKVSEKESSPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQA----KNTE 58
Query: 146 NGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENI 205
G ++VA+K++IK+ L G E + E+ I + + NI
Sbjct: 59 TG---------EDVAVKILIKKAL----------KGNKVQLEALYDELDILQRLHH-PNI 98
Query: 206 VSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIV 265
V+F D+ ES+ +YII +L GGE+F I+K F+E+ + ++ ++ +AVKYMH IV
Sbjct: 99 VAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIV 158
Query: 266 HRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSK 325
HRD+KPENLL+ ID +S + P + +ADFG++K
Sbjct: 159 HRDLKPENLLY--ID---------KSDESP--------------------LVVADFGIAK 187
Query: 326 QIYQTN--TKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVL 383
++ P G++GY APEV+ + + D+W +G + YT+LCG+ F E++
Sbjct: 188 RLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDF 247
Query: 384 TEKISRGEY--TFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
++ + GEY F RP+WD +S+ AK + K L +DP+KR T+ +LL+DPW+
Sbjct: 248 LDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWI 299
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 165 bits (418), Expect = 1e-40
Identities = 105/328 (32%), Positives = 157/328 (47%), Gaps = 59/328 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y L + IG+GAFS V R + + E A K+I NT K
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTG-------------HEYAAKII------NTKKLSAR 53
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
+ K ++ + + NIV D E ++Y++ +L+ GGE+F +IV
Sbjct: 54 DHQKLEREARICRLL-------KHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE 106
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
Y+SE + H I+Q+ AV + HQ+G+VHRD+KPENLL
Sbjct: 107 YYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLL---------------------- 144
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIY--QTNTKTPCGTVGYTAPEVVKDERYSMQV 356
VKLADFGL+ ++ Q GT GY +PEV++ E Y V
Sbjct: 145 ---------ASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPV 195
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D+W G +LY +L G+PPF+DE L ++I G Y F P WD ++ AKN + ++L +
Sbjct: 196 DIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTI 255
Query: 417 DPAKRYTSEQLLQDPWLNSYDCLPSADH 444
+PAKR T+ + L+ PW+ + S H
Sbjct: 256 NPAKRITAHEALKHPWVCQRSTVASMMH 283
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 162 bits (410), Expect = 1e-39
Identities = 102/327 (31%), Positives = 160/327 (48%), Gaps = 58/327 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + T+ E A K+I NT K
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGL-------------EFAAKII------NTKKLSAR 51
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E ++Y++ +L+ GGE+F +IV
Sbjct: 52 DFQKLEREARICRKL-------QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE 104
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ ++ Y H GIVHRD+KPENLL
Sbjct: 105 FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLL---------------------- 142
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVKDERYSMQVD 357
VKLADFGL+ ++ + GT GY +PEV+K + YS VD
Sbjct: 143 ---------ASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVD 193
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AK+ + +L V+
Sbjct: 194 IWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVN 253
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADH 444
P KR T++Q L+ PW+ + + + SA H
Sbjct: 254 PKKRITADQALKVPWICNRERVASAIH 280
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 162 bits (410), Expect = 1e-39
Identities = 102/327 (31%), Positives = 160/327 (48%), Gaps = 58/327 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + T+ E A K+I NT K
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGL-------------EFAAKII------NTKKLSAR 51
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E ++Y++ +L+ GGE+F +IV
Sbjct: 52 DFQKLEREARICRKL-------QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE 104
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ ++ Y H GIVHRD+KPENLL
Sbjct: 105 FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLL---------------------- 142
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVKDERYSMQVD 357
VKLADFGL+ ++ + GT GY +PEV+K + YS VD
Sbjct: 143 ---------ASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVD 193
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AK+ + +L V+
Sbjct: 194 IWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVN 253
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADH 444
P KR T++Q L+ PW+ + + + SA H
Sbjct: 254 PKKRITADQALKVPWICNRERVASAIH 280
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 162 bits (410), Expect = 1e-39
Identities = 102/327 (31%), Positives = 160/327 (48%), Gaps = 58/327 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + T+ E A K+I NT K
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGL-------------EFAAKII------NTKKLSAR 51
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E ++Y++ +L+ GGE+F +IV
Sbjct: 52 DFQKLEREARICRKL-------QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE 104
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ ++ Y H GIVHRD+KPENLL
Sbjct: 105 FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLL---------------------- 142
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVKDERYSMQVD 357
VKLADFGL+ ++ + GT GY +PEV+K + YS VD
Sbjct: 143 ---------ASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVD 193
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AK+ + +L V+
Sbjct: 194 IWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVN 253
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADH 444
P KR T++Q L+ PW+ + + + SA H
Sbjct: 254 PKKRITADQALKVPWICNRERVASAIH 280
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 162 bits (410), Expect = 1e-39
Identities = 102/327 (31%), Positives = 160/327 (48%), Gaps = 58/327 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + T+ E A K+I NT K
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGL-------------EFAAKII------NTKKLSAR 51
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E ++Y++ +L+ GGE+F +IV
Sbjct: 52 DFQKLEREARICRKL-------QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE 104
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ ++ Y H GIVHRD+KPENLL
Sbjct: 105 FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLL---------------------- 142
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVKDERYSMQVD 357
VKLADFGL+ ++ + GT GY +PEV+K + YS VD
Sbjct: 143 ---------ASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVD 193
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AK+ + +L V+
Sbjct: 194 IWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVN 253
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADH 444
P KR T++Q L+ PW+ + + + SA H
Sbjct: 254 PKKRITADQALKVPWICNRERVASAIH 280
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 162 bits (410), Expect = 1e-39
Identities = 102/327 (31%), Positives = 160/327 (48%), Gaps = 58/327 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + T+ E A K+I NT K
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGL-------------EFAAKII------NTKKLSAR 51
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E ++Y++ +L+ GGE+F +IV
Sbjct: 52 DFQKLEREARICRKL-------QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE 104
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ ++ Y H GIVHRD+KPENLL
Sbjct: 105 FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLL---------------------- 142
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVKDERYSMQVD 357
VKLADFGL+ ++ + GT GY +PEV+K + YS VD
Sbjct: 143 ---------ASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVD 193
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AK+ + +L V+
Sbjct: 194 IWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVN 253
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADH 444
P KR T++Q L+ PW+ + + + SA H
Sbjct: 254 PKKRITADQALKVPWICNRERVASAIH 280
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 162 bits (410), Expect = 1e-39
Identities = 102/327 (31%), Positives = 160/327 (48%), Gaps = 58/327 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + T+ E A K+I NT K
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGL-------------EFAAKII------NTKKLSAR 51
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E ++Y++ +L+ GGE+F +IV
Sbjct: 52 DFQKLEREARICRKL-------QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE 104
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ ++ Y H GIVHRD+KPENLL
Sbjct: 105 FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLL---------------------- 142
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVKDERYSMQVD 357
VKLADFGL+ ++ + GT GY +PEV+K + YS VD
Sbjct: 143 ---------ASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVD 193
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AK+ + +L V+
Sbjct: 194 IWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVN 253
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADH 444
P KR T++Q L+ PW+ + + + SA H
Sbjct: 254 PKKRITADQALKVPWICNRERVASAIH 280
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 162 bits (410), Expect = 1e-39
Identities = 102/327 (31%), Positives = 160/327 (48%), Gaps = 58/327 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + T+ E A K+I NT K
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGL-------------EFAAKII------NTKKLSAR 51
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E ++Y++ +L+ GGE+F +IV
Sbjct: 52 DFQKLEREARICRKL-------QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE 104
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ ++ Y H GIVHRD+KPENLL
Sbjct: 105 FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLL---------------------- 142
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVKDERYSMQVD 357
VKLADFGL+ ++ + GT GY +PEV+K + YS VD
Sbjct: 143 ---------ASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVD 193
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AK+ + +L V+
Sbjct: 194 IWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVN 253
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADH 444
P KR T++Q L+ PW+ + + + SA H
Sbjct: 254 PKKRITADQALKVPWICNRERVASAIH 280
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 162 bits (410), Expect = 1e-39
Identities = 102/327 (31%), Positives = 160/327 (48%), Gaps = 58/327 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + T+ E A K+I NT K
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGL-------------EFAAKII------NTKKLSAR 51
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E ++Y++ +L+ GGE+F +IV
Sbjct: 52 DFQKLEREARICRKL-------QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE 104
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ ++ Y H GIVHRD+KPENLL
Sbjct: 105 FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLL---------------------- 142
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVKDERYSMQVD 357
VKLADFGL+ ++ + GT GY +PEV+K + YS VD
Sbjct: 143 ---------ASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVD 193
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AK+ + +L V+
Sbjct: 194 IWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVN 253
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADH 444
P KR T++Q L+ PW+ + + + SA H
Sbjct: 254 PKKRITADQALKVPWICNRERVASAIH 280
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 162 bits (410), Expect = 1e-39
Identities = 102/327 (31%), Positives = 160/327 (48%), Gaps = 58/327 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + T+ E A K+I NT K
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGL-------------EFAAKII------NTKKLSAR 51
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E ++Y++ +L+ GGE+F +IV
Sbjct: 52 DFQKLEREARICRKL-------QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE 104
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ ++ Y H GIVHRD+KPENLL
Sbjct: 105 FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLL---------------------- 142
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVKDERYSMQVD 357
VKLADFGL+ ++ + GT GY +PEV+K + YS VD
Sbjct: 143 ---------ASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVD 193
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AK+ + +L V+
Sbjct: 194 IWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVN 253
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADH 444
P KR T++Q L+ PW+ + + + SA H
Sbjct: 254 PKKRITADQALKVPWICNRERVASAIH 280
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 162 bits (410), Expect = 1e-39
Identities = 102/327 (31%), Positives = 160/327 (48%), Gaps = 58/327 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + T+ E A K+I NT K
Sbjct: 11 NYDVKEELGKGAFSVVRRCVHKTTGL-------------EFAAKII------NTKKLSAR 51
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E ++Y++ +L+ GGE+F +IV
Sbjct: 52 DFQKLEREARICRKL-------QHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE 104
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ ++ Y H GIVHRD+KPENLL
Sbjct: 105 FYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLL---------------------- 142
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVKDERYSMQVD 357
VKLADFGL+ ++ + GT GY +PEV+K + YS VD
Sbjct: 143 ---------ASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVD 193
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AK+ + +L V+
Sbjct: 194 IWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVN 253
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADH 444
P KR T++Q L+ PW+ + + + SA H
Sbjct: 254 PKKRITADQALKVPWICNRERVASAIH 280
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 159 bits (403), Expect = 8e-39
Identities = 101/328 (30%), Positives = 158/328 (47%), Gaps = 59/328 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +++G+GAFS V R + ++ E A K+I NT K
Sbjct: 13 NYDIKEELGKGAFSIVKRCVQKSTGF-------------EFAAKII------NTKKLTAR 53
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K ++ +++ NIV D + E Y+Y++ +L+ GGE+F +IV
Sbjct: 54 DFQKLEREARICRKL-------HHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVARE 106
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
++SE + H I+Q+ +V + HQ G+VHRD+KPENLL
Sbjct: 107 FYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLL---------------------- 144
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP--CGTVGYTAPEVVKDERYSMQV 356
VKLADFGL+ ++ + GT GY +PEV+K E Y V
Sbjct: 145 ---------ASKAKGAAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSV 195
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D+W G +LY +L G+PPF+DE L +I G Y + P WD ++ AKN + ++L V
Sbjct: 196 DIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTV 255
Query: 417 DPAKRYTSEQLLQDPWLNSYDCLPSADH 444
+P KR T+ + L+ PW+ + + S H
Sbjct: 256 NPNKRITAAEALKHPWICQRERVASVVH 283
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 159 bits (402), Expect = 1e-38
Identities = 116/391 (29%), Positives = 179/391 (45%), Gaps = 71/391 (18%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y L +++G+GAFS V R + + Q Y A K+I NT K
Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTG----------QGY---AAKII------NTKKLSAR 53
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
+ K ++ + + NIV D E ++Y++ +L+ GGE+F +IV
Sbjct: 54 DHQKLEREARICRLL-------KHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE 106
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
Y+SE + H I+Q+ +V + H GIVHRD+KPENLL
Sbjct: 107 YYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLL---------------------- 144
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIY--QTNTKTPCGTVGYTAPEVVKDERYSMQV 356
VKLADFGL+ ++ Q GT GY +PEV++ + Y V
Sbjct: 145 ---------ASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPV 195
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
DMW G +LY +L G+PPF+DE L ++I G Y F P WD ++ AK+ + K+L +
Sbjct: 196 DMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTI 255
Query: 417 DPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKA----------YK 466
+PAKR T+ + L+ PW+ + S H K+ ++ + + A +
Sbjct: 256 NPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFS 315
Query: 467 KNASLLYSPAAVAMRDAFDVSNAVQRIEDDK 497
SLL P V +++ + SN ED K
Sbjct: 316 AAKSLLKKPDGV--KESTESSNTTIEDEDVK 344
>YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 513
Score = 158 bits (399), Expect = 2e-38
Identities = 95/280 (33%), Positives = 149/280 (52%), Gaps = 24/280 (8%)
Query: 157 KEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEK 216
++VA+K+ QQ N ++K KN + +L + IV+ ++ V I + +K
Sbjct: 224 QQVAVKIFHAQQ--NDDQK---KNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQK 278
Query: 217 YYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLF 276
Y ++ E + GE+F IV+ T +D S+ + +QL +KY+H+ I+HRDIKPEN+L
Sbjct: 279 Y--LVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILL 336
Query: 277 EPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTP 335
+ ++PS + P VK+ADFGL+K + T T
Sbjct: 337 N-----------ITRRENPS----QVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTL 381
Query: 336 CGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDE-KIDVLTEKISRGEYTF 394
CGT Y APEV+ + Y+ +VD+W G +LY LCGFPPF D+ L E+I + +Y F
Sbjct: 382 CGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAF 441
Query: 395 LRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLN 434
P+WD+I D + + LL ++P +RY ++ L PW N
Sbjct: 442 YSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFN 481
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 447
Score = 157 bits (397), Expect = 4e-38
Identities = 99/321 (30%), Positives = 166/321 (50%), Gaps = 59/321 (18%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y + +G G+F V + ++N ++VAIK+++K+ L N +
Sbjct: 46 NYIFGRTLGAGSFGVVRQARKLSTN-------------EDVAIKILLKKALQGNNVQ--- 89
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
+ + +E++I + +S NIVSF D+ ES+ +YI+ +L GGE+F I+
Sbjct: 90 -------LQMLYEELSILQKLSH-PNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRG 141
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
F+E + +I Q+ AV+YMH +VHRD+KPEN+L+ +D +S + P
Sbjct: 142 KFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLY--VD---------KSENSP--- 187
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQI--YQTNTKTPCGTVGYTAPEVVKDERYSMQV 356
+ +ADFG++KQ+ + G++GY APEV+ + +
Sbjct: 188 -----------------LVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPC 230
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEY--TFLRPWWDQISDGAKNCVRKLL 414
D+W +G + YT+LCG+ PF E ++ E+ + Y TF P+WD IS K + K L
Sbjct: 231 DIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKAL 290
Query: 415 EVDPAKRYTSEQLLQDPWLNS 435
++PA R T+ +LL DPW+ S
Sbjct: 291 RLNPADRPTATELLDDPWITS 311
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 157 bits (396), Expect = 5e-38
Identities = 109/347 (31%), Positives = 164/347 (46%), Gaps = 56/347 (16%)
Query: 88 QEENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNG 147
QE+ +T Q EP P + + Y+L +++G G F Y C+
Sbjct: 66 QEKQKLINHQKQSTLQQPEPILGRPFEDIKEKYSLGRELGRGQFGITYI-------CTEI 118
Query: 148 ASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVS 207
+S K A K I+K++L T + E V +EI I +S NIV
Sbjct: 119 SSG------KNFACKSILKRKLIRTKDR-----------EDVRREIQIMHYLSGQPNIVE 161
Query: 208 FIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHR 267
E + +++ EL GGE+F +I K ++SE + +IR + V+ H +G++HR
Sbjct: 162 IKGAYEDRQSVHLVMELCEGGELFDKITKRGHYSEKAAAEIIRSVVKVVQICHFMGVIHR 221
Query: 268 DIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI 327
D+KPEN L L S D+ S+ L K DFG+S I
Sbjct: 222 DLKPENFL-------------LSSKDEASSML-----------------KATDFGVSVFI 251
Query: 328 YQTNT-KTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEK 386
+ + G+ Y APEV+K Y +D+W G +LY +LCG PPF+ E + E+
Sbjct: 252 EEGKVYEDIVGSAYYVAPEVLK-RNYGKAIDIWSAGVILYILLCGNPPFWAETDKGIFEE 310
Query: 387 ISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
I RGE F W IS+ AK+ VR +L+ DP KR+T+ Q+L+ PW+
Sbjct: 311 ILRGEIDFESEPWPSISESAKDLVRNMLKYDPKKRFTAAQVLEHPWI 357
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 155 bits (392), Expect = 1e-37
Identities = 116/379 (30%), Positives = 182/379 (47%), Gaps = 64/379 (16%)
Query: 82 GKDGTSQEENTYDESSDATTTPQEE-PEDVFPEQTELKD-YTLIQKIGEGAFSKVYRGIP 139
G TS S D P EE E+ F + + Y + + IG+G F+ V
Sbjct: 6 GGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVV----- 60
Query: 140 STSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIV 199
C +++ +E A+K+I K + +G E + E++I + V
Sbjct: 61 --KECVERSTA------REYALKIIKKSKC-----RGKE--------HMIQNEVSILRRV 99
Query: 200 SSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYM 259
NIV I+ + Y++ EL+ GG++F I ++E + ++ LA+A+KY+
Sbjct: 100 KH-PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYL 158
Query: 260 HQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLA 319
H L IVHRDIKPENLL + D S L KL
Sbjct: 159 HSLNIVHRDIKPENLL-------------VYEHQDGSKSL-----------------KLG 188
Query: 320 DFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPF--FD 377
DFGL+ I T CGT Y APE++ + Y ++VD+W G + Y +LCGFPPF
Sbjct: 189 DFGLAT-IVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSG 247
Query: 378 EKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYD 437
+ +VL ++I G+ F P+WD +SD AK + +L VD +R+++ Q+L+ PW+N D
Sbjct: 248 DDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVND-D 306
Query: 438 CLPSADHSNAPSTGEKRRH 456
LP +H + + G+ ++H
Sbjct: 307 GLPENEHQLSVA-GKIKKH 324
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 155 bits (391), Expect = 2e-37
Identities = 98/332 (29%), Positives = 162/332 (48%), Gaps = 66/332 (19%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + IG G++S+ R + +N E A+KVI D+
Sbjct: 418 YVVKETIGVGSYSECKRCVHKATNM-------------EYAVKVI------------DKS 452
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
S ++L H NI++ D + K+ Y++ EL+ GGE+ +I++ +
Sbjct: 453 KRDPSEEIEILLRYGQHP------NIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKF 506
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
FSE + V+ + V+Y+H G+VHRD+KP N+L+ +D NP+
Sbjct: 507 FSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILY--VDESGNPE------------- 551
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN--TKTPCGTVGYTAPEVVKDERYSMQVD 357
+++ DFG +KQ+ N TPC T + APEV+K + Y D
Sbjct: 552 ---------------CLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCD 596
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISR---GEYTFLRPWWDQISDGAKNCVRKLL 414
+W +G +LYT+L G+ PF + D E ++R G++T W+ +S+ AK+ V K+L
Sbjct: 597 IWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKML 656
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCLPSADHSN 446
VDP +R T++Q+LQ PW+ D LP + S+
Sbjct: 657 HVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSH 688
Score = 89.0 bits (219), Expect = 2e-17
Identities = 84/317 (26%), Positives = 139/317 (43%), Gaps = 69/317 (21%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
E+ + + L++ +G+G+F KV+ T S A+KV+ K L
Sbjct: 55 EKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHL----------YAMKVLKKATLKVR 104
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
++ +T +L ++ H V + FQ K Y I+ + L GG++F
Sbjct: 105 DRV------RTKMERDILADVN-HPFV-----VKLHYAFQTEGKLYLIL-DFLRGGDLFT 151
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+ K F+E+ + + +LA + ++H LGI++RD+KPEN+L +
Sbjct: 152 RLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLD--------------- 196
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI--YQTNTKTPCGTVGYTAPEVVKDE 350
+EG +KL DFGLSK+ ++ + CGTV Y APEVV +
Sbjct: 197 -------EEG------------HIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQ 237
Query: 351 RYSMQVDMWGVGCVLYTVLCGFPPFFD---EKIDVLTEKISRGEYTFLRPWWDQISDGAK 407
+S D W G +++ +L G PF ++ L K G FL S A+
Sbjct: 238 GHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFL-------STEAQ 290
Query: 408 NCVRKLLEVDPAKRYTS 424
+ +R L + +PA R S
Sbjct: 291 SLLRALFKRNPANRLGS 307
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 153 bits (387), Expect = 6e-37
Identities = 96/326 (29%), Positives = 158/326 (48%), Gaps = 66/326 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + IG G++S R I +N E A+K+I K + T
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNM-------------EFAVKIIDKSKRDPT------- 461
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
+EI I NI++ D + KY Y++ EL+ GGE+ +I++ +
Sbjct: 462 -----------EEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKF 510
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
FSE + V+ + V+Y+H G+VHRD+KP N+L+ +D NP+
Sbjct: 511 FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY--VDESGNPES------------ 556
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN--TKTPCGTVGYTAPEVVKDERYSMQVD 357
+++ DFG +KQ+ N TPC T + APEV+K + Y D
Sbjct: 557 ----------------IRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACD 600
Query: 358 MWGVGCVLYTVLCGFPPFF---DEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+W +G +LYT+L G+ PF D+ + + +I G+++ +W+ +SD AK+ V K+L
Sbjct: 601 IWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKML 660
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCLP 440
VDP +R T+ +L+ PW+ +D LP
Sbjct: 661 HVDPHQRLTAALVLRHPWIVHWDQLP 686
Score = 92.0 bits (227), Expect = 2e-18
Identities = 83/314 (26%), Positives = 142/314 (44%), Gaps = 69/314 (21%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
E+ + + L++ +G+G+F KV+ + S Q Y A+KV+ K L
Sbjct: 61 EKADPSQFELLKVLGQGSFGKVFL-------VKKISGSDARQLY---AMKVLKKATLKVR 110
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
++ +T +L E+ + IV ++E Y+I + L GG++F
Sbjct: 111 DRV------RTKMERDILVEV-------NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFT 157
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+ K F+E+ + + +LA A+ ++H LGI++RD+KPEN+L +
Sbjct: 158 RLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLD--------------- 202
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI--YQTNTKTPCGTVGYTAPEVVKDE 350
+EG +KL DFGLSK+ ++ + CGTV Y APEVV
Sbjct: 203 -------EEG------------HIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRR 243
Query: 351 RYSMQVDMWGVGCVLYTVLCGFPPF-FDEKIDVLTE--KISRGEYTFLRPWWDQISDGAK 407
++ D W G +++ +L G PF ++ + +T K G FL P A+
Sbjct: 244 GHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSP-------EAQ 296
Query: 408 NCVRKLLEVDPAKR 421
+ +R L + +PA R
Sbjct: 297 SLLRMLFKRNPANR 310
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 153 bits (387), Expect = 6e-37
Identities = 107/351 (30%), Positives = 173/351 (48%), Gaps = 58/351 (16%)
Query: 115 TELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQL----- 169
T L+ Y + + IG+G F+ V I ++ KE A+K+I K +
Sbjct: 193 TLLEKYKIGKVIGDGNFAVVKECIDRSTG-------------KEFALKIIDKAKCCGKQC 239
Query: 170 --PNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAG 227
NT+ + G ST + E++I + V NI+ ++ E+ +++ EL+ G
Sbjct: 240 APSNTDTSCEAIVG--STEHLIENEVSILRRVKH-PNIIMLVEEMETATELFLVMELVKG 296
Query: 228 GEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKP 287
G++F I T ++E ++ LANA++Y+H L IVHRDIKPENLL + P+
Sbjct: 297 GDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLL---VCEYPDGTK 353
Query: 288 KLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVV 347
L KL DFGL+ + + T CGT Y APE++
Sbjct: 354 SL---------------------------KLGDFGLAT-VVEGPLYTVCGTPTYVAPEII 385
Query: 348 KDERYSMQVDMWGVGCVLYTVLCGFPPFFDEK--IDVLTEKISRGEYTFLRPWWDQISDG 405
+ Y ++VD+W G + Y +LCGFPPF E + L ++I G+ F P+WD I+D
Sbjct: 386 AETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDS 445
Query: 406 AKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRH 456
AK + ++L+V+ R T+ Q+L PW++ D ++ A TG+ ++H
Sbjct: 446 AKELISQMLQVNVEARCTAGQILSHPWVS--DDASQENNMQAEVTGKLKQH 494
>Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 382
Score = 152 bits (383), Expect = 2e-36
Identities = 88/276 (31%), Positives = 135/276 (48%), Gaps = 41/276 (14%)
Query: 191 KEIAIHKIVSSGENIVSFIDFQES----EKYYYIIQELLAGGEIFGEIVKY--TYFSEDL 244
+E+ H S G +IV +D E+ ++ II E + GGE+F I + F+E
Sbjct: 83 QEVDHHWQASGGPHIVCILDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQAFTERE 142
Query: 245 SRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVF 304
+ ++R + A++++H I HRD+KPENLL+ S + D
Sbjct: 143 AAEIMRDIGTAIQFLHSHNIAHRDVKPENLLYT------------------SKEKD---- 180
Query: 305 RPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCV 364
V+KL DFG +K+ Q +TPC T Y APEV+ E+Y DMW +G +
Sbjct: 181 ---------AVLKLTDFGFAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVI 231
Query: 365 LYTVLCGFPPFFDEKIDVLT----EKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAK 420
+Y +LCGFPPF+ ++ +I G+Y F P W ++S+ AK +R LL+ DP +
Sbjct: 232 MYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQLIRLLLKTDPTE 291
Query: 421 RYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRH 456
R T Q + PW+N +P A E + H
Sbjct: 292 RLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKDH 327
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 151 bits (381), Expect = 3e-36
Identities = 108/366 (29%), Positives = 166/366 (44%), Gaps = 63/366 (17%)
Query: 104 QEEPEDVFPEQTELKD----YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEV 159
++E +D+ P++ K Y + +G G S V R I + KE
Sbjct: 3 KDEEDDLLPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETG-------------KEF 49
Query: 160 AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYY 219
A K+I L T + G+ E +EI+I + V I+ D ES+ + +
Sbjct: 50 AAKII---DLGATTESGE--TNPYHMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVF 104
Query: 220 IIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPI 279
++ EL GE+F + SE +R ++RQ+ V+Y+H IVHRD+KPEN+L
Sbjct: 105 LVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENIL---- 160
Query: 280 DFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGT 338
LDE VK+ DFG +KQ+ + T CGT
Sbjct: 161 -------------------LDEN-----------HNVKITDFGFAKQLQEGEKLTNLCGT 190
Query: 339 VGYTAPEVVK------DERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEY 392
GY APE +K YS +VD+W G +++T+L G PPF+ K V+ I G+Y
Sbjct: 191 PGYLAPETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKY 250
Query: 393 TFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGE 452
+F P W IS+ K+ +RK L VDP++R T +++L+ P+ N + H P
Sbjct: 251 SFTSPEWADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFFNQMVLMGDRRHPAPPIAPA 310
Query: 453 KRRHSH 458
+ H
Sbjct: 311 QTNSRH 316
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 521
Score = 150 bits (379), Expect = 5e-36
Identities = 104/315 (33%), Positives = 154/315 (48%), Gaps = 57/315 (18%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
YTL +++G G F Y C+ ++ K A K I K++L KGD+
Sbjct: 73 YTLSKELGRGQFGVTYL-------CTEKSTG------KRFACKSISKKKLVT---KGDK- 115
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
E + +EI I + +S NIV F E EK ++ EL AGGE+F I+ +
Sbjct: 116 -------EDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRILAKGH 168
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
+SE + V RQ+ N V H +G++HRD+KPEN L L S D+ +
Sbjct: 169 YSERAAASVCRQIVNVVNICHFMGVMHRDLKPENFL-------------LSSKDEKA--- 212
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVDM 358
++K DFGLS I + K G+ Y APEV+K RY ++D+
Sbjct: 213 ---------------LIKATDFGLSVFIEEGRVYKDIVGSAYYVAPEVLK-RRYGKEIDI 256
Query: 359 WGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDP 418
W G +LY +L G PPF+ E + + I GE F W IS+ AK+ VR++L DP
Sbjct: 257 WSAGIILYILLSGVPPFWAETEKGIFDAILEGEIDFESQPWPSISNSAKDLVRRMLTQDP 316
Query: 419 AKRYTSEQLLQDPWL 433
+R ++ ++L+ PWL
Sbjct: 317 KRRISAAEVLKHPWL 331
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 149 bits (376), Expect = 1e-35
Identities = 96/327 (29%), Positives = 154/327 (46%), Gaps = 66/327 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + IG G++S R I +T+N E A+K+I D+
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNM-------------EFAVKII------------DKS 460
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
S ++L H NI++ D + +Y Y++ +L+ GGE+ I+K
Sbjct: 461 KRDPSEEIEILMRYGQHP------NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKC 514
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
FSE + ++ ++ V Y+H G+VHRD+KP N+L+ D S
Sbjct: 515 FSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYM----------------DESASA 558
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN--TKTPCGTVGYTAPEVVKDERYSMQVD 357
D +++ DFG +KQ+ N TPC T + APEV+ + Y D
Sbjct: 559 DS--------------IRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACD 604
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTE---KISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+W +G + YT+L G+ PF + D E +I G+++ WD ISDGAK+ + +L
Sbjct: 605 IWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHML 664
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCLPS 441
+DP +RYT+EQ+L+ W+ D LP+
Sbjct: 665 HMDPHQRYTAEQILKHSWITHRDQLPN 691
Score = 98.2 bits (243), Expect = 3e-20
Identities = 86/320 (26%), Positives = 142/320 (43%), Gaps = 73/320 (22%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
E+ + + L++ +G+G+F KV+ T + Q Y A+KV+ K L
Sbjct: 66 EKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAG-------QLY---AMKVLKKASLKVR 115
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
++ +T +L E+ + IV ++E Y+I + L GG++F
Sbjct: 116 DRV------RTKMERDILVEV-------NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFT 162
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+ K F+E+ + + +LA A+ ++HQLGIV+RD+KPEN+L + I I
Sbjct: 163 RLSKEVLFTEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHI---------- 212
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK--TPCGTVGYTAPEVVKDE 350
KL DFGLSK+ K + CGTV Y APEVV
Sbjct: 213 ------------------------KLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRR 248
Query: 351 RYSMQVDMWGVGCVLYTVLCGFPPFFDEKID-----VLTEKISRGEYTFLRPWWDQISDG 405
+S D W G +++ +L G PF + + +L K+ ++ +S
Sbjct: 249 GHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQF---------LSAE 299
Query: 406 AKNCVRKLLEVDPAKRYTSE 425
A++ +R L + +PA R SE
Sbjct: 300 AQSLLRMLFKRNPANRLGSE 319
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 149 bits (376), Expect = 1e-35
Identities = 112/387 (28%), Positives = 184/387 (46%), Gaps = 66/387 (17%)
Query: 106 EPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVII 165
+ + V+P+ +Y + + +G GA C + + K+VAIK+I
Sbjct: 207 DDQSVYPKALR-DEYIMSKTLGSGA-------------CGEVKLAFERKTCKKVAIKIIS 252
Query: 166 KQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELL 225
K++ + + + T ++LK++ I+ I +F D ++ YYI+ EL+
Sbjct: 253 KRKFAIGSAREADPALNVETEIEILKKLNHPCIIK----IKNFFDAED----YYIVLELM 304
Query: 226 AGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNP 285
GGE+F ++V E + Q+ AV+Y+H+ GI+HRD+KPEN+L
Sbjct: 305 EGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVL---------- 354
Query: 286 KPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAP 344
L S ++ ++K+ DFG SK + +T+ +T CGT Y AP
Sbjct: 355 ---LSSQEEDC------------------LIKITDFGHSKILGETSLMRTLCGTPTYLAP 393
Query: 345 EV---VKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDV-LTEKISRGEYTFLRPWWD 400
EV V Y+ VD W +G +L+ L G+PPF + + V L ++I+ G+Y F+ W
Sbjct: 394 EVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWA 453
Query: 401 QISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNS-------YDCLPSADHSNA-PSTGE 452
++S+ A + V+KLL VDP R+T+E+ L+ PWL D L + S A P
Sbjct: 454 EVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLA 513
Query: 453 KRRHSHKHSRKAYKKNASLLYSPAAVA 479
+ S K R+ + A PA A
Sbjct: 514 QPSTSRKRPREGEAEGAETTKRPAVCA 540
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 148 bits (373), Expect = 2e-35
Identities = 82/248 (33%), Positives = 127/248 (51%), Gaps = 35/248 (14%)
Query: 191 KEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIR 250
+EI I NI++ D + K+ Y++ EL+ GGE+ I++ YFSE + V+
Sbjct: 455 EEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLC 514
Query: 251 QLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXX 310
+ + Y+H G+VHRD+KP N+L+ S P +
Sbjct: 515 TITKTMDYLHSQGVVHRDLKPSNILYRD------------ESGSPES------------- 549
Query: 311 XXXXVVKLADFGLSKQIYQTN--TKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTV 368
+++ DFG +KQ+ N TPC T + APEV+K + Y D+W +G +LYT+
Sbjct: 550 -----IRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTM 604
Query: 369 LCGFPPFF---DEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSE 425
L GF PF D+ + + +I G+Y WD ISD AK+ V K+L VDP +R T+
Sbjct: 605 LAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAM 664
Query: 426 QLLQDPWL 433
Q+L+ PW+
Sbjct: 665 QVLKHPWV 672
Score = 85.9 bits (211), Expect = 1e-16
Identities = 70/265 (26%), Positives = 118/265 (44%), Gaps = 59/265 (22%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
E+ + + L++ +G+G++ KV+ S Q Y A+KV+ K L
Sbjct: 52 EKADPSQFELLKVLGQGSYGKVFL-------VRKVKGSDAGQLY---AMKVLKKATL--- 98
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
K D K +L E+ + IV ++E Y+I + L GG++F
Sbjct: 99 -KVRDRVRSKME--RDILAEV-------NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFT 148
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+ K F+E+ + + +LA A+ ++H LGI++RD+KPEN+L +
Sbjct: 149 RLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLD--------------- 193
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI--YQTNTKTPCGTVGYTAPEVVKDE 350
+EG +K+ DFGLSK+ + + CGT+ Y APEVV
Sbjct: 194 -------EEG------------HIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRR 234
Query: 351 RYSMQVDMWGVGCVLYTVLCGFPPF 375
++ D W G +++ +L G PF
Sbjct: 235 GHTQSADWWSFGVLMFEMLTGSLPF 259
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 147 bits (372), Expect = 3e-35
Identities = 99/324 (30%), Positives = 166/324 (50%), Gaps = 66/324 (20%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
EQ + +Y L++ IG+G F+KV A ++ KEVA+K+I K QL
Sbjct: 13 EQPHIGNYRLLKTIGKGNFAKVKL-----------ARHILTG--KEVAVKIIDKTQL--- 56
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
+S+ +++ +E+ I K+++ NIV + E+EK Y++ E +GGE+F
Sbjct: 57 ---------NSSSLQKLFREVRIMKVLNH-PNIVKLFEVIETEKTLYLVMEYASGGEVFD 106
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+V + E +R RQ+ +AV+Y HQ IVHRD+K ENLL +
Sbjct: 107 YLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLD--------------- 151
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-YQTNTKTPCGTVGYTAPEVVKDER 351
+K+ADFG S + + T CG+ Y APE+ + ++
Sbjct: 152 -------------------ADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKK 192
Query: 352 Y-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCV 410
Y +VD+W +G +LYT++ G PF + + L E++ RG+Y P++ +S +N +
Sbjct: 193 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI--PFY--MSTDCENLL 248
Query: 411 RKLLEVDPAKRYTSEQLLQDPWLN 434
+K L ++P+KR T EQ+++D W+N
Sbjct: 249 KKFLILNPSKRGTLEQIMKDRWMN 272
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 147 bits (372), Expect = 3e-35
Identities = 99/324 (30%), Positives = 166/324 (50%), Gaps = 66/324 (20%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
EQ + +Y L++ IG+G F+KV A ++ KEVA+K+I K QL
Sbjct: 13 EQPHIGNYRLLKTIGKGNFAKVKL-----------ARHILTG--KEVAVKIIDKTQL--- 56
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
+S+ +++ +E+ I K+++ NIV + E+EK Y++ E +GGE+F
Sbjct: 57 ---------NSSSLQKLFREVRIMKVLNH-PNIVKLFEVIETEKTLYLVMEYASGGEVFD 106
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+V + E +R RQ+ +AV+Y HQ IVHRD+K ENLL +
Sbjct: 107 YLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLD--------------- 151
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-YQTNTKTPCGTVGYTAPEVVKDER 351
+K+ADFG S + + T CG+ Y APE+ + ++
Sbjct: 152 -------------------ADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKK 192
Query: 352 Y-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCV 410
Y +VD+W +G +LYT++ G PF + + L E++ RG+Y P++ +S +N +
Sbjct: 193 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI--PFY--MSTDCENLL 248
Query: 411 RKLLEVDPAKRYTSEQLLQDPWLN 434
+K L ++P+KR T EQ+++D W+N
Sbjct: 249 KKFLILNPSKRGTLEQIMKDRWMN 272
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 147 bits (372), Expect = 3e-35
Identities = 99/324 (30%), Positives = 166/324 (50%), Gaps = 66/324 (20%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
EQ + +Y L++ IG+G F+KV A ++ KEVA+K+I K QL
Sbjct: 46 EQPHIGNYRLLKTIGKGNFAKVKL-----------ARHILTG--KEVAVKIIDKTQL--- 89
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
+S+ +++ +E+ I K+++ NIV + E+EK Y++ E +GGE+F
Sbjct: 90 ---------NSSSLQKLFREVRIMKVLNH-PNIVKLFEVIETEKTLYLVMEYASGGEVFD 139
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+V + E +R RQ+ +AV+Y HQ IVHRD+K ENLL +
Sbjct: 140 YLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLD--------------- 184
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-YQTNTKTPCGTVGYTAPEVVKDER 351
+K+ADFG S + + T CG+ Y APE+ + ++
Sbjct: 185 -------------------ADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKK 225
Query: 352 Y-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCV 410
Y +VD+W +G +LYT++ G PF + + L E++ RG+Y P++ +S +N +
Sbjct: 226 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI--PFY--MSTDCENLL 281
Query: 411 RKLLEVDPAKRYTSEQLLQDPWLN 434
+K L ++P+KR T EQ+++D W+N
Sbjct: 282 KKFLILNPSKRGTLEQIMKDRWMN 305
>At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 541
Score = 147 bits (372), Expect = 3e-35
Identities = 101/315 (32%), Positives = 150/315 (47%), Gaps = 57/315 (18%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
YTL +++G G F Y C+ ++ K+ A K I K++L K D +
Sbjct: 91 YTLGKELGRGQFGVTYL-------CTENSTG------KKYACKSISKKKLVTKADKDDMR 137
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
+EI I + +S NIV F E EK ++ EL AGGE+F I+ +
Sbjct: 138 -----------REIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRIIAKGH 186
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
++E + V RQ+ N VK H +G++HRD+KPEN L L S D+ +
Sbjct: 187 YTERAAASVCRQIVNVVKICHFMGVLHRDLKPENFL-------------LSSKDEKA--- 230
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVDM 358
++K DFGLS I + + G+ Y APEV++ RY +VD+
Sbjct: 231 ---------------LIKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVLR-RRYGKEVDI 274
Query: 359 WGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDP 418
W G +LY +L G PPF+ E + + I G F W IS AK+ VR++L DP
Sbjct: 275 WSAGIILYILLSGVPPFWAETEKGIFDAILEGHIDFESQPWPSISSSAKDLVRRMLTADP 334
Query: 419 AKRYTSEQLLQDPWL 433
+R ++ +LQ PWL
Sbjct: 335 KRRISAADVLQHPWL 349
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 147 bits (371), Expect = 4e-35
Identities = 111/354 (31%), Positives = 165/354 (46%), Gaps = 34/354 (9%)
Query: 186 AEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLS 245
A Q +E I ++V NIV D ++Y++ E+L G E+ I K F+E +
Sbjct: 418 ASQAQREARILEMVQGHPNIVQLHDVHSDPLHFYLVMEILTGNELLERIRKLERFTESEA 477
Query: 246 RHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFR 305
++RQL +AVKY+H IVHRD+KPEN+LFE ID +LR D +L
Sbjct: 478 ADIMRQLVSAVKYLHDKRIVHRDLKPENILFESID----SSARLRLVDFGFARL-----L 528
Query: 306 PXXXXXXXXVVKLAD--FGLSKQIYQTNTKTPCGTVGYTAPEVV----KDERYSMQVDMW 359
P V++ +GL + +++TPC T+ Y APEV+ Y+ Q D+W
Sbjct: 529 PNSMEQQLKSVQVLRKMYGLIAHNHSLHSETPCFTLQYAAPEVLDVGDSQPEYNEQCDLW 588
Query: 360 GVGCVLYTVLCGFPPFF----DEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLE 415
+G VL+T+L G PF E + ++I R E++F W +S AKN + LL
Sbjct: 589 SLGVVLFTMLSGQVPFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADAKNLITGLLT 648
Query: 416 VDPAKRYTSEQLLQDPWLNSYDCL------PSADHSNAPSTGEKRRHSHKHSRKAYKKNA 469
VDP KR + ++L WL S + PS S+A T + + H A +
Sbjct: 649 VDPKKRLSMQELTAHMWLKSSASMDTPLQTPSILPSSADETFNETLRAFLH---ANRDGF 705
Query: 470 SLLYSPAAVAMRDAFDVSNAVQRIEDDKRMTPGPKXXXXXXXLGVLAEDAEAEI 523
LL AA M+ ++R DK + G L E+ EAE+
Sbjct: 706 HLLDVAAAPLMK-----RRGIKRQSGDKDAS-GNSKNSRVTQFECLPEEQEAEM 753
Score = 84.3 bits (207), Expect = 4e-16
Identities = 74/315 (23%), Positives = 139/315 (43%), Gaps = 61/315 (19%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEV-AIKVIIKQQLPN 171
E+ ++++ L++ +G+GA+ KV+ V + + + A+KV+ K ++
Sbjct: 10 EKVSMENFALLRVLGKGAYGKVFL-----------VRKVGGKDHNTIYAMKVLRKTRVLT 58
Query: 172 TNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIF 231
K T E + E + + + +V+ +++ +I+ E + GGE+F
Sbjct: 59 KQK----------TLEHTMAERQVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELF 108
Query: 232 GEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRS 291
+ +F + +R VI +L A+ +HQ +++RD+K EN+L +
Sbjct: 109 THLCSRGHFDLEAARFVIAELVVAIDSLHQRKVIYRDLKLENILLD-------------- 154
Query: 292 SDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQ---TNTKTPCGTVGYTAPEVVK 348
+EG VKL DFGLSK + CGT+ Y +PEV+
Sbjct: 155 --------EEG------------HVKLTDFGLSKLFLPGELDRANSYCGTIEYMSPEVIN 194
Query: 349 --DERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGA 406
+ YS VD W +G + + +L G PF + ++ I++ T P+ + A
Sbjct: 195 RPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNSSKDIAKRIMTKKVPFPKTMDVDA 254
Query: 407 KNCVRKLLEVDPAKR 421
++ + +LLE KR
Sbjct: 255 RDFIGQLLEKKLEKR 269
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 147 bits (371), Expect = 4e-35
Identities = 110/372 (29%), Positives = 174/372 (46%), Gaps = 57/372 (15%)
Query: 75 HHVQIVQGKDGTSQEENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKV 134
+ ++I++ D S TY +P E PE+ K Y + +K+G GA+ V
Sbjct: 115 NRMRILKNDDVISLSHPTYKAFVFKDLSPNESIG--LPEEIN-KTYYVNRKLGSGAYGLV 171
Query: 135 YRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIA 194
R + T C ++ A+K++ K L G + S ++VL E
Sbjct: 172 -RLVYDTRTC------------QQFAMKIVKKNML-----SGARPSTNFSDPDRVLNEAK 213
Query: 195 IHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLAN 254
I K +S +V D + Y++ E + GG++ I+ SED+S+ Q+ +
Sbjct: 214 IMKNLSH-PCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCH 272
Query: 255 AVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXX 314
AVKY+H GI HRD+KP+N+L E ++D T L
Sbjct: 273 AVKYLHDRGITHRDLKPDNVLLE--------------TNDEETLL--------------- 303
Query: 315 VVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKD---ERYSMQVDMWGVGCVLYTVLC 370
K++DFGLSK + + + +T CGT Y APEV+ E Y+ +VD+W +G VL+T L
Sbjct: 304 --KVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLS 361
Query: 371 GFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQD 430
G PF DE ++I +G + + P W +S AK + ++L VDP +R + + +LQ
Sbjct: 362 GTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDPERRPSIDDVLQS 421
Query: 431 PWLNSYDCLPSA 442
WL L A
Sbjct: 422 SWLRDAPMLQKA 433
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 147 bits (370), Expect = 5e-35
Identities = 108/368 (29%), Positives = 169/368 (45%), Gaps = 57/368 (15%)
Query: 118 KDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGD 177
K YTL +++G G F Y C ++ A K I+K++L +K D
Sbjct: 100 KLYTLGKELGRGQFGITY-------TCKENSTG------NTYACKSILKRKL---TRKQD 143
Query: 178 EKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKY 237
+ V +EI I + +S ENIV E + +++ EL G E+F I+
Sbjct: 144 --------IDDVKREIQIMQYLSGQENIVEIKGAYEDRQSIHLVMELCGGSELFDRIIAQ 195
Query: 238 TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPST 297
++SE + VIR + N V+ H +G++HRD+KPEN L L S+D+ +
Sbjct: 196 GHYSEKAAAGVIRSVLNVVQICHFMGVIHRDLKPENFL-------------LASTDENA- 241
Query: 298 KLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQV 356
++K DFGLS I + + G+ Y APEV++ Y ++
Sbjct: 242 -----------------MLKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVLR-RSYGKEI 283
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D+W G +LY +LCG PPF+ E + +I +GE F W IS+ AK+ VRKLL
Sbjct: 284 DIWSAGIILYILLCGVPPFWSETEKGIFNEIIKGEIDFDSQPWPSISESAKDLVRKLLTK 343
Query: 417 DPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAYKKNASLLYSPA 476
DP +R ++ Q L+ PW+ + S S ++ R +K + A K A L
Sbjct: 344 DPKQRISAAQALEHPWIRGGEAPDKPIDSAVLSRMKQFRAMNKLKKLALKVIAESLSEEE 403
Query: 477 AVAMRDAF 484
++ F
Sbjct: 404 IKGLKTMF 411
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 147 bits (370), Expect = 5e-35
Identities = 112/393 (28%), Positives = 174/393 (43%), Gaps = 65/393 (16%)
Query: 101 TTPQEEPEDVFPEQTEL--------KDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVI 152
+TP P V T L K Y+L +++G G F Y C +
Sbjct: 53 STPSSNPVSVRDPDTILGKPFEDIRKFYSLGKELGRGQFGITYM-------CKEIGTG-- 103
Query: 153 AQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQ 212
A K I+K++L + K D K +EI I + +S NIV
Sbjct: 104 ----NTYACKSILKRKLISKQDKEDVK-----------REIQIMQYLSGQPNIVEIKGAY 148
Query: 213 ESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPE 272
E + +++ EL AGGE+F I+ ++SE + +IR + N V+ H +G+VHRD+KPE
Sbjct: 149 EDRQSIHLVMELCAGGELFDRIIAQGHYSERAAAGIIRSIVNVVQICHFMGVVHRDLKPE 208
Query: 273 NLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT 332
N L SS + + L K DFGLS I +
Sbjct: 209 NFLL--------------SSKEENAML-----------------KATDFGLSVFIEEGKV 237
Query: 333 -KTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGE 391
+ G+ Y APEV++ Y ++D+W G +LY +L G PPF+ E + +++ +GE
Sbjct: 238 YRDIVGSAYYVAPEVLR-RSYGKEIDIWSAGVILYILLSGVPPFWAENEKGIFDEVIKGE 296
Query: 392 YTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTG 451
F+ W IS+ AK+ VRK+L DP +R T+ Q+L+ PW+ + S S
Sbjct: 297 IDFVSEPWPSISESAKDLVRKMLTKDPKRRITAAQVLEHPWIKGGEAPDKPIDSAVLSRM 356
Query: 452 EKRRHSHKHSRKAYKKNASLLYSPAAVAMRDAF 484
++ R +K + A K A L ++ F
Sbjct: 357 KQFRAMNKLKKLALKVIAESLSEEEIKGLKTMF 389
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 146 bits (369), Expect = 7e-35
Identities = 101/267 (37%), Positives = 134/267 (49%), Gaps = 42/267 (15%)
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVS-SGENIVSFIDFQESEKYYYIIQELLAGGEIF 231
NKK EK + V EIAI K VS NI+ +DF E+ Y+I EL GGE+F
Sbjct: 63 NKKMMEKK-----QDFVKNEIAILKRVSYEHPNILHLVDFFETVNNLYLITELATGGELF 117
Query: 232 GEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRS 291
I F E + ++R +AVKY+H GIVHRD+KPENLL+
Sbjct: 118 DRICAKGSFYEADAAALMRTTTSAVKYLHDNGIVHRDLKPENLLYR-------------- 163
Query: 292 SDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT----KTPCGTVGYTAPEVV 347
S DP++ L +ADFGLS Y+ + T CGT Y APEV
Sbjct: 164 SKDPNSDL-----------------LIADFGLS-HFYEDSQYYMLMTACGTPEYMAPEVF 205
Query: 348 KDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAK 407
+ Y VDMW +G + Y +L G+ PF + E I EYTF P W IS+ AK
Sbjct: 206 RRTGYGKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAK 265
Query: 408 NCVRKLLEVDPAKRYTSEQLLQDPWLN 434
+ ++K LE DP+KR T+ L+ P+L+
Sbjct: 266 DFIKKCLENDPSKRLTAADALKHPFLS 292
>CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 425
Score = 146 bits (368), Expect = 9e-35
Identities = 84/315 (26%), Positives = 151/315 (47%), Gaps = 44/315 (13%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESE----KYYYIIQELLAGGEIFGEIVK--YTYF 240
++ +E+ +H + S ++VS D ++ ++ E + GGE+F I + F
Sbjct: 107 QKARREVELHVMASGHGHVVSVHDVYKNSYNGVDCLLVVMENMKGGELFNRIQERGQKAF 166
Query: 241 SEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLD 300
+E + ++ ++ +AV ++H++ I HRD+KPENLL+
Sbjct: 167 TEREAAGIVNEICSAVAHLHRMSIAHRDLKPENLLY------------------------ 202
Query: 301 EGVFRPXXXXXXXXVVKLADFGLSKQIYQT---NTKTPCGTVGYTAPEVVKDERYSMQVD 357
+KL DFG +K+ ++ KT C T Y APEV+ E+Y D
Sbjct: 203 -------VTTASNAALKLTDFGFAKKTDESEPQGLKTACFTPYYCAPEVLGTEKYDKSCD 255
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLT----EKISRGEYTFLRPWWDQISDGAKNCVRKL 413
+W +G ++Y +LCG+PPF+ + ++ KI G+YTF P WD +S+ AK+ +RKL
Sbjct: 256 LWSIGVIMYILLCGYPPFYSQHGQPMSPGMKAKIKSGQYTFPSPEWDCVSEAAKDLIRKL 315
Query: 414 LEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAYKKNASLLY 473
L +P +R T EQ ++ W++ Y +P + + ++R + AS+
Sbjct: 316 LRTEPTERITIEQTMEHKWISHYRRVPDTPLFTSSNLNDQREQWTDMQDEMEATLASMRV 375
Query: 474 SPAAVAMRDAFDVSN 488
P + ++ D +N
Sbjct: 376 GPENIQIKSLGDSNN 390
>CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 443
Score = 146 bits (368), Expect = 9e-35
Identities = 84/315 (26%), Positives = 151/315 (47%), Gaps = 44/315 (13%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESE----KYYYIIQELLAGGEIFGEIVK--YTYF 240
++ +E+ +H + S ++VS D ++ ++ E + GGE+F I + F
Sbjct: 125 QKARREVELHVMASGHGHVVSVHDVYKNSYNGVDCLLVVMENMKGGELFNRIQERGQKAF 184
Query: 241 SEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLD 300
+E + ++ ++ +AV ++H++ I HRD+KPENLL+
Sbjct: 185 TEREAAGIVNEICSAVAHLHRMSIAHRDLKPENLLY------------------------ 220
Query: 301 EGVFRPXXXXXXXXVVKLADFGLSKQIYQT---NTKTPCGTVGYTAPEVVKDERYSMQVD 357
+KL DFG +K+ ++ KT C T Y APEV+ E+Y D
Sbjct: 221 -------VTTASNAALKLTDFGFAKKTDESEPQGLKTACFTPYYCAPEVLGTEKYDKSCD 273
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLT----EKISRGEYTFLRPWWDQISDGAKNCVRKL 413
+W +G ++Y +LCG+PPF+ + ++ KI G+YTF P WD +S+ AK+ +RKL
Sbjct: 274 LWSIGVIMYILLCGYPPFYSQHGQPMSPGMKAKIKSGQYTFPSPEWDCVSEAAKDLIRKL 333
Query: 414 LEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAYKKNASLLY 473
L +P +R T EQ ++ W++ Y +P + + ++R + AS+
Sbjct: 334 LRTEPTERITIEQTMEHKWISHYRRVPDTPLFTSSNLNDQREQWTDMQDEMEATLASMRV 393
Query: 474 SPAAVAMRDAFDVSN 488
P + ++ D +N
Sbjct: 394 GPENIQIKSLGDSNN 408
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 144 bits (362), Expect = 4e-34
Identities = 105/332 (31%), Positives = 164/332 (48%), Gaps = 76/332 (22%)
Query: 118 KDYTLIQKI-GEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
KD+++I ++ G+GAF+ V + I T+ K A+K+I K+++
Sbjct: 195 KDFSIIDEVVGQGAFATVKKAIERTTG-------------KTFAVKIISKRKVIGN---- 237
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
+G T E VL+++ + IV F E + YY++ E ++GG++ +
Sbjct: 238 --MDGVTRELE-VLQKL-------NHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAA 287
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
+ ED R + RQ+ A+KY+H +GI HRD+KP+N+L E DDP
Sbjct: 288 HGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIE--------------QDDP- 332
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSK-QIYQTNTKTPCGTVGYTAPEVVK------- 348
+VK+ DFGL+K Q + KT CGT+ Y APEV++
Sbjct: 333 -----------------VLVKITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVS 375
Query: 349 ----DER--YSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWD-Q 401
+ER YS VDMW +GC++Y +L G PF D L ++I RG Y P D +
Sbjct: 376 PDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSY-HEGPLKDFR 434
Query: 402 ISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
IS+ A++ + LL+VDP R T+ + L PW+
Sbjct: 435 ISEEARDFIDSLLQVDPNNRSTAAKALNHPWI 466
>Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 144 bits (362), Expect = 4e-34
Identities = 91/272 (33%), Positives = 138/272 (50%), Gaps = 42/272 (15%)
Query: 171 NTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEI 230
+T KK +++G+ + EI I K+V NI+ +D + K Y+I EL G E+
Sbjct: 50 HTCKKFQKRDGR-KVRKAAKNEIGILKMVKH-PNILQLVDVFVTRKEYFIFLELATGREV 107
Query: 231 FGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLR 290
F I+ Y+SE + +V+RQ+ AV Y+H L IVHR++K ENL++ + K+
Sbjct: 108 FDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVY----YNRLKNSKIV 163
Query: 291 SSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDE 350
SD KL+ G+ K PCGT Y APEVV +
Sbjct: 164 ISDFHLAKLENGLI----------------------------KEPCGTPEYLAPEVVGRQ 195
Query: 351 RYSMQVDMWGVGCVLYTVLCGFPPFFDEKID--------VLTEKISRGEYTFLRPWWDQI 402
RY VD W +G ++Y +L G PPF++E + L KI G+Y F P+WD I
Sbjct: 196 RYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDI 255
Query: 403 SDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLN 434
S AK+ V +L+EV+ +R T+E+ + W++
Sbjct: 256 SQAAKDLVTRLMEVEQDQRITAEEAISHEWIS 287
>7290629 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 359
Score = 143 bits (361), Expect = 6e-34
Identities = 82/266 (30%), Positives = 134/266 (49%), Gaps = 42/266 (15%)
Query: 186 AEQVLKEIAIHKIVSSGENIVSFIDFQES----EKYYYIIQELLAGGEIFGEIVKYT--Y 239
+E+ +E+ +H VS IV+ ID E+ K ++ E + GGE+F I
Sbjct: 54 SERARREVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGA 113
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
F+E + ++ ++ AV Y+H I HRD+KPENLL+ ++ P+ L
Sbjct: 114 FTEREAAQIMHEICAAVDYLHSRDIAHRDLKPENLLY--------------TTTQPNATL 159
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVDM 358
KL DFG +K+ + + T +TPC T Y APEV+ E+Y D+
Sbjct: 160 -----------------KLTDFGFAKETFTSYTLQTPCYTPYYVAPEVLGPEKYDKSCDI 202
Query: 359 WGVGCVLYTVLCGFPPFFDEK----IDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
W +G V+Y ++CGFPPF+ + +I G+Y F P W +S AK+ ++ +L
Sbjct: 203 WSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGML 262
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCLP 440
VDP+KR + ++ + W+ Y+ +P
Sbjct: 263 NVDPSKRLRIQDVISNKWIAQYNAVP 288
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 142 bits (359), Expect = 1e-33
Identities = 101/324 (31%), Positives = 164/324 (50%), Gaps = 66/324 (20%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
EQ + +Y L + IG+G F+KV A V+ +EVA+K+I K QL T
Sbjct: 53 EQPHIGNYRLQKTIGKGNFAKVKL-----------ARHVLTG--REVAVKIIDKTQLNPT 99
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
+ +++ +E+ I KI++ NIV + E+EK Y++ E +GGE+F
Sbjct: 100 S------------LQKLFREVRIMKILNH-PNIVKLFEVIETEKTLYLVMEYASGGEVFD 146
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+V + E +R RQ+ +AV+Y HQ IVHRD+K ENLL +
Sbjct: 147 YLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLD--------------- 191
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDER 351
+K+ADFG S + N T CG+ Y APE+ + ++
Sbjct: 192 -------------------GDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKK 232
Query: 352 YS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCV 410
Y +VD+W +G +LYT++ G PF + + L E++ RG+Y P++ +S +N +
Sbjct: 233 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI--PFY--MSTDCENLL 288
Query: 411 RKLLEVDPAKRYTSEQLLQDPWLN 434
+KLL ++P KR + EQ+++D W+N
Sbjct: 289 KKLLVLNPIKRGSLEQIMKDRWMN 312
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 142 bits (357), Expect = 2e-33
Identities = 100/337 (29%), Positives = 156/337 (45%), Gaps = 64/337 (18%)
Query: 107 PEDVFPEQTELKD----YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIK 162
PED P+ K+ Y IG G S V R + A + EV +
Sbjct: 7 PEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCV------HRATGHEFAVKIMEVTAE 60
Query: 163 VIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQ 222
+ +QL +E T +L+++A H +I++ ID ES + +++
Sbjct: 61 RLSPEQL-------EEVREATRRETHILRQVAGHP------HIITLIDSYESSSFMFLVF 107
Query: 223 ELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFI 282
+L+ GE+F + + SE +R ++R L AV ++H IVHRD+KPEN+L
Sbjct: 108 DLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENIL------- 160
Query: 283 PNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQ-TNTKTPCGTVGY 341
LD+ + ++L+DFG S + + CGT GY
Sbjct: 161 ----------------LDDNM-----------QIRLSDFGFSCHLEPGEKLRELCGTPGY 193
Query: 342 TAPEVVK---DER---YSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFL 395
APE++K DE Y +VD+W G +L+T+L G PPF+ + ++ I G+Y F
Sbjct: 194 LAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFS 253
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
P WD S K+ + +LL+VDP R T+EQ LQ P+
Sbjct: 254 SPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPF 290
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 142 bits (357), Expect = 2e-33
Identities = 98/328 (29%), Positives = 156/328 (46%), Gaps = 67/328 (20%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
DY +++KIG GA S V++ C A+ ++ A+K++ K T
Sbjct: 453 DYEILEKIGNGAHSVVHK-------CQMKATR------RKYAVKIVKKAVFDAT------ 493
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV-KY 237
+E+ I S + +V D E E Y+I+EL GGE+ ++V K
Sbjct: 494 ------------EEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKK 541
Query: 238 TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPST 297
+ SE ++ L NAV+Y+H + HRD+ N+LF D DPS+
Sbjct: 542 SLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKD------------GDPSS 589
Query: 298 KLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN--TKTPCGTVGYTAPEVVKDERYSMQ 355
+++ DFG +KQ N TPC T + APEV++ + Y
Sbjct: 590 ------------------LRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRS 631
Query: 356 VDMWGVGCVLYTVLCGFPPFF---DEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRK 412
D+W +G +L+T+L G PF ++ D + +++ G+ + P WD ISD AK+ VRK
Sbjct: 632 CDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRK 691
Query: 413 LLEVDPAKRYTSEQLLQDPWLNSYDCLP 440
+L+VDP +R T++Q LQ W+ + LP
Sbjct: 692 MLDVDPNRRVTAKQALQHKWIGQKEALP 719
Score = 95.5 bits (236), Expect = 2e-19
Identities = 71/265 (26%), Positives = 120/265 (44%), Gaps = 59/265 (22%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
E+ + + + L++ +G+G+F KV+ + +G A+KV+ K L
Sbjct: 97 EKADPRQFELLKVLGQGSFGKVFL-VRKVRGRDSG---------HVYAMKVLKKATLKVR 146
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
+++ +T +L I S IV ++E Y+I + L GG++F
Sbjct: 147 DRQ------RTKLERNILAHI-------SHPFIVKLHYAFQTEGKLYLILDFLRGGDLFT 193
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+ K F+ED + + +L A++++H LGIV+RD+KPEN+L +
Sbjct: 194 RLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLD--------------- 238
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP--CGTVGYTAPEVVKDE 350
+K+ DFGLSK+ + KT CGTV Y APEV+
Sbjct: 239 -------------------ADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRR 279
Query: 351 RYSMQVDMWGVGCVLYTVLCGFPPF 375
+SM D W +G +++ +L G PF
Sbjct: 280 GHSMAADFWSLGVLMFEMLTGHLPF 304
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 142 bits (357), Expect = 2e-33
Identities = 98/328 (29%), Positives = 156/328 (46%), Gaps = 67/328 (20%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
DY +++KIG GA S V++ C A+ ++ A+K++ K T
Sbjct: 396 DYEILEKIGNGAHSVVHK-------CQMKATR------RKYAVKIVKKAVFDAT------ 436
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV-KY 237
+E+ I S + +V D E E Y+I+EL GGE+ ++V K
Sbjct: 437 ------------EEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKK 484
Query: 238 TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPST 297
+ SE ++ L NAV+Y+H + HRD+ N+LF D DPS+
Sbjct: 485 SLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKD------------GDPSS 532
Query: 298 KLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN--TKTPCGTVGYTAPEVVKDERYSMQ 355
+++ DFG +KQ N TPC T + APEV++ + Y
Sbjct: 533 ------------------LRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRS 574
Query: 356 VDMWGVGCVLYTVLCGFPPFF---DEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRK 412
D+W +G +L+T+L G PF ++ D + +++ G+ + P WD ISD AK+ VRK
Sbjct: 575 CDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRK 634
Query: 413 LLEVDPAKRYTSEQLLQDPWLNSYDCLP 440
+L+VDP +R T++Q LQ W+ + LP
Sbjct: 635 MLDVDPNRRVTAKQALQHKWIGQKEALP 662
Score = 98.2 bits (243), Expect = 3e-20
Identities = 76/293 (25%), Positives = 130/293 (43%), Gaps = 64/293 (21%)
Query: 90 ENTYDESSDATTTPQEEPEDVFP-----EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNC 144
EN ++ + T + E D+ E+ + + + L++ +G+G+F KV+ +
Sbjct: 12 ENEIEQGEEKTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFL-VRKVRGR 70
Query: 145 SNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGEN 204
+G A+KV+ K L +++ +T +L I S
Sbjct: 71 DSG---------HVYAMKVLKKATLKVRDRQ------RTKLERNILAHI-------SHPF 108
Query: 205 IVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGI 264
IV ++E Y+I + L GG++F + K F+ED + + +L A++++H LGI
Sbjct: 109 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGI 168
Query: 265 VHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLS 324
V+RD+KPEN+L + +K+ DFGLS
Sbjct: 169 VYRDLKPENILLD----------------------------------ADGHIKVTDFGLS 194
Query: 325 KQIYQTNTKTP--CGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPF 375
K+ + KT CGTV Y APEV+ +SM D W +G +++ +L G PF
Sbjct: 195 KEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPF 247
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 141 bits (356), Expect = 2e-33
Identities = 83/257 (32%), Positives = 125/257 (48%), Gaps = 41/257 (15%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSR 246
E LKE+ I + VS NI+ D E+ +++++ +L+ GE+F + + SE +R
Sbjct: 69 EATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETR 128
Query: 247 HVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRP 306
++R L + +H+L IVHRD+KPEN+L LD+ +
Sbjct: 129 KIMRALLEVICTLHKLNIVHRDLKPENIL-----------------------LDDNMN-- 163
Query: 307 XXXXXXXXVVKLADFGLSKQIYQ-TNTKTPCGTVGYTAPEVVKDER------YSMQVDMW 359
+KL DFG S Q+ + CGT Y APE+++ Y +VDMW
Sbjct: 164 ---------IKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMW 214
Query: 360 GVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPA 419
G ++YT+L G PPF+ K ++ I G Y F P WD SD K+ V + L V P
Sbjct: 215 STGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQ 274
Query: 420 KRYTSEQLLQDPWLNSY 436
RYT+E+ L P+ Y
Sbjct: 275 NRYTAEEALAHPFFQQY 291
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 141 bits (356), Expect = 2e-33
Identities = 99/342 (28%), Positives = 163/342 (46%), Gaps = 68/342 (19%)
Query: 114 QTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTN 173
+T + +Y + + +GEG+F+KV ++V Q AIK++ +
Sbjct: 13 RTRVGNYEMGRTLGEGSFAKV----------KYAKNTVTGDQ---AAIKILDR------- 52
Query: 174 KKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGE 233
EK + EQ+ +EI+ K++ N+V I+ S+ YI+ EL+ GGE+F +
Sbjct: 53 ----EKVFRHKMVEQLKREISTMKLIKH-PNVVEIIEVMASKTKIYIVLELVNGGELFDK 107
Query: 234 IVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSD 293
I + ED +R +QL NAV Y H G+ HRD+KPENL+ +
Sbjct: 108 IAQQGRLKEDEARRYFQQLINAVDYCHSRGVYHRDLKPENLILD---------------- 151
Query: 294 DPSTKLDEGVFRPXXXXXXXXVVKLADFGLS---KQIYQTNT-KTPCGTVGYTAPEVVKD 349
V+K++DFGLS +Q+ + T CGT Y APEV+ D
Sbjct: 152 ------------------ANGVLKVSDFGLSAFSRQVREDGLLHTACGTPNYVAPEVLSD 193
Query: 350 ERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKN 408
+ Y D+W G +L+ ++ G+ PF + + L ++I + E++ PW+ Q GAK
Sbjct: 194 KGYDGAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRICKAEFS-CPPWFSQ---GAKR 249
Query: 409 CVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPST 450
++++LE +P R + +LL+D W PS D + T
Sbjct: 250 VIKRILEPNPITRISIAELLEDEWFKKGYKPPSFDQDDEDIT 291
>HsM4506035 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 471
Score = 141 bits (355), Expect = 3e-33
Identities = 104/340 (30%), Positives = 163/340 (47%), Gaps = 79/340 (23%)
Query: 192 EIAIHKIVSSGENIVSFID-FQESEKYYY---------IIQELLAGGEIFGEIVKYTYFS 241
E+ +H + ++ NIV I+ F S ++ + I+ E++ GGE+F I ++ +F+
Sbjct: 62 EVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFT 121
Query: 242 EDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDE 301
E + V +Q+A A+++ H L I HRD+KPENLLF K S D P
Sbjct: 122 EKQASQVTKQIALALRHCHLLNIAHRDLKPENLLF-----------KDNSLDAP------ 164
Query: 302 GVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDER---------- 351
VKL DFG +K I Q + TP T Y AP+V++ +R
Sbjct: 165 --------------VKLCDFGFAK-IDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGII 209
Query: 352 --------YSMQVDMWGVGCVLYTVLCGFPPFFDEKID-----VLTEKISRGEYTFLRPW 398
Y+ D+W +G ++Y +LCG+PPF+ + + KI G + F
Sbjct: 210 PTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRRKIMTGSFEFPEEE 269
Query: 399 WDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDC----LPSAD--HSNAPSTGE 452
W QIS+ AK+ VRKLL+V P +R T E +L PWLNS + LPSA A G
Sbjct: 270 WSQISEMAKDVVRKLLKVKPERRLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGI 329
Query: 453 KRRHSHKHSRKAYKKNASLLYSPAAVAMRDAFDVSNAVQR 492
++ H+ ++ A++ V+++ V+N + R
Sbjct: 330 QQAHA--------EQLANMRIQDLKVSLKPLHSVNNPILR 361
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 140 bits (354), Expect = 4e-33
Identities = 98/325 (30%), Positives = 164/325 (50%), Gaps = 66/325 (20%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
EQ + +Y L++ IG+G F+KV A ++ +EVAIK+I K QL T
Sbjct: 49 EQPHIGNYRLLKTIGKGNFAKVKL-----------ARHILTG--REVAIKIIDKTQLNPT 95
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
+ +++ +E+ I KI++ NIV + E++K Y+I E +GG++F
Sbjct: 96 S------------LQKLFREVRIMKILNH-PNIVKLFEVIETQKTLYLIMEYASGGKVFD 142
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+V + E +R RQ+ +AV+Y HQ IVHRD+K ENLL +
Sbjct: 143 YLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLD--------------- 187
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-YQTNTKTPCGTVGYTAPEVVKDER 351
+K+ADFG S + T CG+ Y APE+ + ++
Sbjct: 188 -------------------ADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKK 228
Query: 352 Y-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCV 410
Y +VD+W +G +LYT++ G PF + + L E++ RG+Y P++ +S +N +
Sbjct: 229 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI--PFY--MSTDCENLL 284
Query: 411 RKLLEVDPAKRYTSEQLLQDPWLNS 435
++ L ++P KR T EQ+++D W+N+
Sbjct: 285 KRFLVLNPIKRGTLEQIMKDRWINA 309
>Hs21237768 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 473
Score = 140 bits (354), Expect = 4e-33
Identities = 104/340 (30%), Positives = 163/340 (47%), Gaps = 79/340 (23%)
Query: 192 EIAIHKIVSSGENIVSFID-FQESEKYYY---------IIQELLAGGEIFGEIVKYTYFS 241
E+ +H + ++ NIV I+ F S ++ + I+ E++ GGE+F I ++ +F+
Sbjct: 62 EVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFT 121
Query: 242 EDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDE 301
E + V +Q+A A+++ H L I HRD+KPENLLF K S D P
Sbjct: 122 EKQASQVTKQIALALRHCHLLNIAHRDLKPENLLF-----------KDNSLDAP------ 164
Query: 302 GVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDER---------- 351
VKL DFG +K I Q + TP T Y AP+V++ +R
Sbjct: 165 --------------VKLCDFGFAK-IDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGII 209
Query: 352 --------YSMQVDMWGVGCVLYTVLCGFPPFFDEKID-----VLTEKISRGEYTFLRPW 398
Y+ D+W +G ++Y +LCG+PPF+ + + KI G + F
Sbjct: 210 PTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRRKIMTGSFEFPEEE 269
Query: 399 WDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDC----LPSAD--HSNAPSTGE 452
W QIS+ AK+ VRKLL+V P +R T E +L PWLNS + LPSA A G
Sbjct: 270 WSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGI 329
Query: 453 KRRHSHKHSRKAYKKNASLLYSPAAVAMRDAFDVSNAVQR 492
++ H+ ++ A++ V+++ V+N + R
Sbjct: 330 QQAHA--------EQLANMRIQDLKVSLKPLHSVNNPILR 361
>Hs21237765 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 471
Score = 140 bits (354), Expect = 4e-33
Identities = 104/340 (30%), Positives = 163/340 (47%), Gaps = 79/340 (23%)
Query: 192 EIAIHKIVSSGENIVSFID-FQESEKYYY---------IIQELLAGGEIFGEIVKYTYFS 241
E+ +H + ++ NIV I+ F S ++ + I+ E++ GGE+F I ++ +F+
Sbjct: 62 EVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFT 121
Query: 242 EDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDE 301
E + V +Q+A A+++ H L I HRD+KPENLLF K S D P
Sbjct: 122 EKQASQVTKQIALALRHCHLLNIAHRDLKPENLLF-----------KDNSLDAP------ 164
Query: 302 GVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDER---------- 351
VKL DFG +K I Q + TP T Y AP+V++ +R
Sbjct: 165 --------------VKLCDFGFAK-IDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGII 209
Query: 352 --------YSMQVDMWGVGCVLYTVLCGFPPFFDEKID-----VLTEKISRGEYTFLRPW 398
Y+ D+W +G ++Y +LCG+PPF+ + + KI G + F
Sbjct: 210 PTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRRKIMTGSFEFPEEE 269
Query: 399 WDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDC----LPSAD--HSNAPSTGE 452
W QIS+ AK+ VRKLL+V P +R T E +L PWLNS + LPSA A G
Sbjct: 270 WSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAGI 329
Query: 453 KRRHSHKHSRKAYKKNASLLYSPAAVAMRDAFDVSNAVQR 492
++ H+ ++ A++ V+++ V+N + R
Sbjct: 330 QQAHA--------EQLANMRIQDLKVSLKPLHSVNNPILR 361
>At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 583
Score = 140 bits (354), Expect = 4e-33
Identities = 94/328 (28%), Positives = 156/328 (46%), Gaps = 59/328 (17%)
Query: 108 EDVFPEQTE-LKD-YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVII 165
+ V +TE LKD Y++ +K+G+G F + + + KE A K I
Sbjct: 120 DSVLGRKTENLKDIYSVGRKLGQGQFGTTFLCVDKKTG-------------KEFACKTIA 166
Query: 166 KQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELL 225
K++L E V +EI I +S N++ + E +++ E+
Sbjct: 167 KRKLTTPED-----------VEDVRREIQIMHHLSGHPNVIQIVGAYEDAVAVHVVMEIC 215
Query: 226 AGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNP 285
AGGE+F I++ +++E + + R + ++ H LG++HRD+KPEN LF
Sbjct: 216 AGGELFDRIIQRGHYTEKKAAELARIIVGVIEACHSLGVMHRDLKPENFLFV-------- 267
Query: 286 KPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPC-GTVGYTAP 344
S D+ + +K DFGLS T T G+ Y AP
Sbjct: 268 -----SGDEEAA------------------LKTIDFGLSVFFKPGETFTDVVGSPYYVAP 304
Query: 345 EVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISD 404
EV++ + YS + D+W G ++Y +L G PPF+DE + E++ +G+ F+ W +S+
Sbjct: 305 EVLR-KHYSHECDVWSAGVIIYILLSGVPPFWDETEQGIFEQVLKGDLDFISEPWPSVSE 363
Query: 405 GAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
AK+ VR++L DP KR T+ ++L PW
Sbjct: 364 SAKDLVRRMLIRDPKKRMTTHEVLCHPW 391
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 140 bits (352), Expect = 6e-33
Identities = 108/385 (28%), Positives = 175/385 (45%), Gaps = 80/385 (20%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
L Y + IG G+FS+V R T+ K AIKV+ +
Sbjct: 60 LARYDIKALIGTGSFSRVVRVEQKTTK-------------KPFAIKVMETR--------- 97
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
E+ G+ E + E+++ + VS IV ++ E+E Y++ EL GGE+F ++
Sbjct: 98 -EREGR----EACVSELSVLRRVSH-RYIVQLMEIFETEDQVYMVMELATGGELFDRLIA 151
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
F+E + +++ +A+ ++Y+H L I HR++KPENLL+ + P + K
Sbjct: 152 QGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLY----YHPGEESK-------- 199
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLS---KQIYQTNTKTPCGTVGYTAPEVVKDERYS 353
+ + DFGL+ K+ KT CGT Y APEV+ + Y+
Sbjct: 200 -------------------ILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT 240
Query: 354 MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKL 413
VDMW +G + Y +L GF PF DE L KI +G+Y + W IS AK+ + KL
Sbjct: 241 SAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKL 300
Query: 414 LEVDPAKRYTSEQLLQDPWLNSYDCLPS----------------ADHSNAPSTGE--KRR 455
L ++ R ++ Q L PW+ + S + HS +P + + K
Sbjct: 301 LILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQRASPHSQSPGSAQSSKSH 360
Query: 456 HSHKHSRKAYKKNASLLYSPAAVAM 480
+SHK K+N ++ SP + +
Sbjct: 361 YSHKSRHMWSKRNLRIVESPLSALL 385
>CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 476
Score = 140 bits (352), Expect = 6e-33
Identities = 100/337 (29%), Positives = 157/337 (45%), Gaps = 61/337 (18%)
Query: 109 DVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQ 168
D PE+ K + +G+G F KV G + SV+A IKQ
Sbjct: 159 DHHPEELTKKYHVTSHSLGKGGFGKVLLGYKKSDR------SVVA-----------IKQL 201
Query: 169 LPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGG 228
+ + KT + E+ + K +S NIV+ D+ KY Y++ E + GG
Sbjct: 202 NTQFSTRCSRAIAKT---RDIRNEVEVMKKLSH-PNIVAIYDWITVAKYSYMVIEYVGGG 257
Query: 229 EIFGEIVKYTY----FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPN 284
E F ++V Y E L ++ QL +A+ Y+H +GI HRDIKPEN+L
Sbjct: 258 EFFSKVVDSKYNRMGLGESLGKYFAFQLIDAILYLHSVGICHRDIKPENILC-------- 309
Query: 285 PKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAP 344
S K + ++KL DFG++K KT CGT Y AP
Sbjct: 310 -----------SDKAER------------CILKLTDFGMAKNSVN-RMKTRCGTPSYNAP 345
Query: 345 EVVKDE--RYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDV-LTEKISRGEYTFLRPWWDQ 401
E+V +E Y+ +VD+W +GCVL+ G+PPF +E D+ + E++ G F W +
Sbjct: 346 EIVANEGVEYTPKVDIWSLGCVLFITFSGYPPFSEEYTDMTMDEQVLTGRLIF-HAQWRR 404
Query: 402 ISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDC 438
I+ +N ++ +L V+P+ R ++ +L+ W+ DC
Sbjct: 405 ITVETQNMIKWMLTVEPSNRPSAVELMSTQWMKCADC 441
>At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 140 bits (352), Expect = 6e-33
Identities = 107/382 (28%), Positives = 175/382 (45%), Gaps = 59/382 (15%)
Query: 106 EPEDVF--PEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKV 163
+PE + P + K Y+L +++G G G+ T C + I A K
Sbjct: 53 DPETILGKPFEDIRKFYSLGRELGRG-------GLGITYMCKEIGTGNI------YACKS 99
Query: 164 IIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQE 223
I+K++L + + D K EI I + +S N+V E +++ E
Sbjct: 100 ILKRKLISELGREDVKT-----------EIQIMQHLSGQPNVVEIKGSYEDRHSVHLVME 148
Query: 224 LLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIP 283
L AGGE+F I+ ++SE + I+ + + V+ H G++HRD+KPEN LF
Sbjct: 149 LCAGGELFDRIIAQGHYSERAAAGTIKSIVDVVQICHLNGVIHRDLKPENFLF------- 201
Query: 284 NPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYT 342
SS + + L K+ DFGLS I + K G+ Y
Sbjct: 202 -------SSKEENAML-----------------KVTDFGLSAFIEEGKIYKDVVGSPYYV 237
Query: 343 APEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQI 402
APEV++ + Y ++D+W G +LY +LCG PPF+ + + + +I + + F+R W I
Sbjct: 238 APEVLR-QSYGKEIDIWSAGVILYILLCGVPPFWADNEEGVFVEILKCKIDFVREPWPSI 296
Query: 403 SDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSR 462
SD AK+ V K+L DP +R T+ Q+L+ PW+ + S S ++ R +K +
Sbjct: 297 SDSAKDLVEKMLTEDPKRRITAAQVLEHPWIKGGEAPEKPIDSTVLSRMKQFRAMNKLKK 356
Query: 463 KAYKKNASLLYSPAAVAMRDAF 484
A K +A L ++ F
Sbjct: 357 LALKVSAVSLSEEEIKGLKTLF 378
>At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 545
Score = 140 bits (352), Expect = 6e-33
Identities = 114/419 (27%), Positives = 182/419 (43%), Gaps = 65/419 (15%)
Query: 83 KDGTSQEENTYDESSDATTTPQEEPEDVFP--EQTELKD-YTLIQKIGEGAFSKVYRGIP 139
K ++ N + + P +DV P QT++ D Y L +++G G F Y
Sbjct: 23 KPNRDRKLNPFAGDFTRSPAPIRVLKDVIPMSNQTQISDKYILGRELGRGEFGITYL--- 79
Query: 140 STSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIV 199
C++ + ++ +A K I K++L E V +E+AI +
Sbjct: 80 ----CTD------RETHEALACKSISKRKLRTA-----------VDIEDVRREVAIMSTL 118
Query: 200 SSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYM 259
N+V E + +++ EL GGE+F IV +++E + V R +A V
Sbjct: 119 PEHPNVVKLKASYEDNENVHLVMELCEGGELFDRIVARGHYTERAAAAVARTIAEVVMMC 178
Query: 260 HQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLA 319
H G++HRD+KPEN LF + + P +K
Sbjct: 179 HSNGVMHRDLKPENFLFAN-----------KKENSP--------------------LKAI 207
Query: 320 DFGLSKQIYQTNTKTPC-GTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDE 378
DFGLS + T G+ Y APEV+K + Y VD+W G ++Y +LCG PPF+ E
Sbjct: 208 DFGLSVFFKPGDKFTEIVGSPYYMAPEVLKRD-YGPGVDVWSAGVIIYILLCGVPPFWAE 266
Query: 379 KIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDC 438
+ I RG F R W QIS+ AK+ V+++L+ DP KR T++Q+L PW+ +
Sbjct: 267 TEQGVALAILRGVLDFKRDPWPQISESAKSLVKQMLDPDPTKRLTAQQVLAHPWIQNAKK 326
Query: 439 LPSADHSNAPSTGEKRRHSHKHSRKAYKKNASLLYSPAAVAMRDAFDVSNAVQRIEDDK 497
P N P R + S K L +++++ + N ++DDK
Sbjct: 327 AP-----NVPLGDIVRSRLKQFSMMNRFKKKVLRVIAEHLSIQEVEVIKNMFSLMDDDK 380
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 490
Score = 139 bits (351), Expect = 8e-33
Identities = 87/250 (34%), Positives = 130/250 (51%), Gaps = 37/250 (14%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSR 246
+ VL+EI I +S N+V E K +++ EL GGE+F IVK ++SE +
Sbjct: 65 DDVLREIQIMHHLSEYPNVVRIESAYEDTKNVHLVMELCEGGELFDRIVKRGHYSEREAA 124
Query: 247 HVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRP 306
+I+ + V+ H LG+VHRD+KPEN LF SSD+ ++
Sbjct: 125 KLIKTIVGVVEACHSLGVVHRDLKPENFLFS-------------SSDEDAS--------- 162
Query: 307 XXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVG---YTAPEVVKDERYSMQVDMWGVGC 363
+K DFGLS ++ T + VG Y APEV+ + Y + D+W G
Sbjct: 163 ---------LKSTDFGLS--VFCTPGEAFSELVGSAYYVAPEVLH-KHYGPECDVWSAGV 210
Query: 364 VLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYT 423
+LY +LCGFPPF+ E + KI +G+ F W IS+ AK+ ++K+LE +P KR T
Sbjct: 211 ILYILLCGFPPFWAESEIGIFRKILQGKLEFEINPWPSISESAKDLIKKMLESNPKKRLT 270
Query: 424 SEQLLQDPWL 433
+ Q+L PW+
Sbjct: 271 AHQVLCHPWI 280
>At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 503
Score = 139 bits (351), Expect = 8e-33
Identities = 102/350 (29%), Positives = 160/350 (45%), Gaps = 60/350 (17%)
Query: 94 DESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIA 153
D + + P DV E E + Y L +++G G F Y I +S
Sbjct: 29 DAAGGKKSAPIRVLSDVPKENIEDR-YLLDRELGRGEFGVTYLCIERSSR---------- 77
Query: 154 QQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQE 213
+A K I K++L E V +E+AI K + +IV+ + E
Sbjct: 78 ---DLLACKSISKRKLRTA-----------VDIEDVKREVAIMKHLPKSSSIVTLKEACE 123
Query: 214 SEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPEN 273
+ +++ EL GGE+F IV +++E + V + + V+ H+ G++HRD+KPEN
Sbjct: 124 DDNAVHLVMELCEGGELFDRIVARGHYTERAAAGVTKTIVEVVQLCHKHGVIHRDLKPEN 183
Query: 274 LLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK 333
LF + + P +K DFGLS ++ K
Sbjct: 184 FLFAN-----------KKENSP--------------------LKAIDFGLSI-FFKPGEK 211
Query: 334 TP--CGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGE 391
G+ Y APEV+K Y ++D+W G +LY +LCG PPF+ E + + I RG
Sbjct: 212 FSEIVGSPYYMAPEVLK-RNYGPEIDIWSAGVILYILLCGVPPFWAESEQGVAQAILRGV 270
Query: 392 YTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPS 441
F R W IS+ AKN VR++LE DP +R T++Q+L+ PW+ + P+
Sbjct: 271 IDFKREPWPNISETAKNLVRQMLEPDPKRRLTAKQVLEHPWIQNAKKAPN 320
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 139 bits (351), Expect = 8e-33
Identities = 104/318 (32%), Positives = 147/318 (45%), Gaps = 68/318 (21%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + IGEG F+KV N G + VA+K++ K EK
Sbjct: 14 YEVGRTIGEGTFAKV----KFARNSETG---------EPVALKILDK-----------EK 49
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
K AEQ+ +EIA K++ N+V + S+ +II E + GGE+F +IV
Sbjct: 50 VLKHKMAEQIRREIATMKLIKH-PNVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGR 108
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
ED +R +QL +AV Y H G+ HRD+KPENLL +D N
Sbjct: 109 MKEDEARRYFQQLIHAVDYCHSRGVYHRDLKPENLL---LDSYGN--------------- 150
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN----TKTPCGTVGYTAPEVVKDERY-SM 354
+K++DFGLS Q T CGT Y APEV+ D Y
Sbjct: 151 ----------------LKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRGYDGA 194
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
DMW G VLY +L G+ PF D + L +KIS GE+ PW +S GA + ++L
Sbjct: 195 TADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISSGEFN-CPPW---LSLGAMKLITRIL 250
Query: 415 EVDPAKRYTSEQLLQDPW 432
+ +P R T +++ +D W
Sbjct: 251 DPNPMTRVTPQEVFEDEW 268
>Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 400
Score = 139 bits (350), Expect = 1e-32
Identities = 82/277 (29%), Positives = 134/277 (47%), Gaps = 43/277 (15%)
Query: 191 KEIAIHKIVSSGENIVSFIDFQES----EKYYYIIQELLAGGEIFGEIVKY--TYFSEDL 244
+E+ +H S +IV +D E+ K I+ E L GGE+F I F+E
Sbjct: 103 REVELHWRASQCPDIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTERE 162
Query: 245 SRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVF 304
+ +++ + A++Y+H + I HRD+KPENLL+ +S P+
Sbjct: 163 ASEIMKSIGEAIQYLHSINIAHRDVKPENLLY--------------TSKRPNA------- 201
Query: 305 RPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVDMWGVGC 363
++KL DFG +K+ N+ TPC T Y APEV+ E+Y DMW +G
Sbjct: 202 ----------ILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGV 251
Query: 364 VLYTVLCGFPPFFDEK----IDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPA 419
++Y +LCG+PPF+ + +I G+Y F P W ++S+ K +R LL+ +P
Sbjct: 252 IMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPT 311
Query: 420 KRYTSEQLLQDPWLNSYDCLPSAD-HSNAPSTGEKRR 455
+R T + + PW+ +P H++ +K R
Sbjct: 312 QRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKER 348
>Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 370
Score = 139 bits (350), Expect = 1e-32
Identities = 82/277 (29%), Positives = 134/277 (47%), Gaps = 43/277 (15%)
Query: 191 KEIAIHKIVSSGENIVSFIDFQES----EKYYYIIQELLAGGEIFGEIVKY--TYFSEDL 244
+E+ +H S +IV +D E+ K I+ E L GGE+F I F+E
Sbjct: 103 REVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTERE 162
Query: 245 SRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVF 304
+ +++ + A++Y+H + I HRD+KPENLL+ +S P+
Sbjct: 163 ASEIMKSIGEAIQYLHSINIAHRDVKPENLLY--------------TSKRPNA------- 201
Query: 305 RPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVDMWGVGC 363
++KL DFG +K+ N+ TPC T Y APEV+ E+Y DMW +G
Sbjct: 202 ----------ILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGV 251
Query: 364 VLYTVLCGFPPFFDEK----IDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPA 419
++Y +LCG+PPF+ + +I G+Y F P W ++S+ K +R LL+ +P
Sbjct: 252 IMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPT 311
Query: 420 KRYTSEQLLQDPWLNSYDCLPSAD-HSNAPSTGEKRR 455
+R T + + PW+ +P H++ +K R
Sbjct: 312 QRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKER 348
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 469
Score = 139 bits (350), Expect = 1e-32
Identities = 101/335 (30%), Positives = 156/335 (46%), Gaps = 61/335 (18%)
Query: 112 PEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPN 171
PE+ K + +G+G F KV G + SV+A IKQ
Sbjct: 161 PEELTNKYHVTSHLLGKGGFGKVLLGYKKSDR------SVVA-----------IKQLNTQ 203
Query: 172 TNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIF 231
+ + KT + E+ + K +S NIV+ D KY Y++ E + GGE F
Sbjct: 204 FSTRCSRAIAKT---RDIQNEVEVMKKLSH-PNIVAIYDCITVAKYSYMVIEYVGGGEFF 259
Query: 232 GEIVKYTY----FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKP 287
++V Y E L ++ QL +AV Y+H +GI HRDIKPEN+L
Sbjct: 260 SKLVDSKYNQMGLGESLGKYFAFQLIDAVLYLHSVGICHRDIKPENILC----------- 308
Query: 288 KLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVV 347
S K + ++KL DFG++K KT CGT Y APE+V
Sbjct: 309 --------SNKAER------------CILKLTDFGMAKNSVN-RMKTHCGTPSYCAPEIV 347
Query: 348 KDE--RYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDV-LTEKISRGEYTFLRPWWDQISD 404
++ Y+ +VD+W +GCVL+ G+PPF +E D+ + E++ G F W +I+D
Sbjct: 348 ANQGVEYTPKVDIWSLGCVLFITFSGYPPFSEEYTDLKMDEQVLTGR-LFFHEQWHRITD 406
Query: 405 GAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCL 439
+N ++ +L V+P R ++ +L+ W+ DCL
Sbjct: 407 ETQNMIQWMLTVEPLIRPSAVELMSTQWMKCADCL 441
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 139 bits (350), Expect = 1e-32
Identities = 102/358 (28%), Positives = 162/358 (44%), Gaps = 75/358 (20%)
Query: 95 ESSDATTTPQEEPEDVFPEQTELKD------------------YTLIQKIGEGAFSKVYR 136
++S+ T+ PQ +P+ P Y L +++G G F Y+
Sbjct: 42 QTSNPTSNPQPKPKPAPPPPPSTSSGSQIGPILNRPMIDLSALYDLHKELGRGQFGITYK 101
Query: 137 GIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIH 196
++ SNG +E A K I K++L + E V +E+ I
Sbjct: 102 ----CTDKSNG---------REYACKSISKRKLI-----------RRKDIEDVRREVMIL 137
Query: 197 KIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAV 256
+ ++ NIV F E + +++ EL +GGE+F I+K +SE + ++ RQ+ N V
Sbjct: 138 QHLTGQPNIVEFRGAYEDKDNLHLVMELCSGGELFDRIIKKGSYSEKEAANIFRQIVNVV 197
Query: 257 KYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVV 316
H +G+VHRD+KPEN L L S+++ S +
Sbjct: 198 HVCHFMGVVHRDLKPENFL-------------LVSNEEDSP------------------I 226
Query: 317 KLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPF 375
K DFGLS I + + G+ Y APEV+ Y ++D+W G +LY +L G PPF
Sbjct: 227 KATDFGLSVFIEEGKVYRDIVGSAYYVAPEVLH-RNYGKEIDVWSAGVMLYILLSGVPPF 285
Query: 376 FDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
+ E + E I G+ W IS+ AK+ +RK+L DP KR T+ + L+ PW+
Sbjct: 286 WGETEKTIFEAILEGKLDLETSPWPTISESAKDLIRKMLIRDPKKRITAAEALEHPWM 343
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 139 bits (350), Expect = 1e-32
Identities = 94/320 (29%), Positives = 148/320 (45%), Gaps = 57/320 (17%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y L+Q++G G FS C + AS K A+KVI K + +
Sbjct: 567 EYNLLQELGRGTFSVCRL-------CEHRASK------KHYAVKVIEKAAVAAAS----- 608
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
TST+ +E+ I + NIV+ E Y++ ELL GGE+ I+
Sbjct: 609 ----TSTSADCWEEVEIMLRYGNHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVG 664
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
E + V+R +A+AV Y+H+ G+VHRD+KP N+++ + P
Sbjct: 665 QMCESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIYASMRQTPE-------------- 710
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN--TKTPCGTVGYTAPEVVKDERYSMQV 356
+KL D G +KQ+ N TPC T + APEV+K + Y +
Sbjct: 711 ----------------TLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDLAC 754
Query: 357 DMWGVGCVLYTVLCGFPPFF---DEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKL 413
D+W +G +LY +L G PF ++ DV+ ++I G+ F W IS AK +R++
Sbjct: 755 DIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDFTSSRWALISVPAKELLRQM 814
Query: 414 LEVDPAKRYTSEQLLQDPWL 433
L + P R T+ ++L+ WL
Sbjct: 815 LHIVPENRPTAARILEHDWL 834
Score = 92.8 bits (229), Expect = 1e-18
Identities = 89/333 (26%), Positives = 149/333 (44%), Gaps = 75/333 (22%)
Query: 101 TTPQEEPEDVFPEQTELKD---------YTLIQKIGEGAFSKVY--RGIPSTSNCSNGAS 149
T P E E+ F + +K+ + L++ +GEG+F KV+ R I + A
Sbjct: 171 TEPLYETENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAM 230
Query: 150 SVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFI 209
V+ K+ +KV K ++ +TN++ ++L ++ IV
Sbjct: 231 KVL----KKATLKV--KDRVRSTNER------------KILADVGHAFIVRL------HY 266
Query: 210 DFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDI 269
FQ K Y I+ + L GG++F + K F+E+ + + +LA A+ ++H LGI++RD+
Sbjct: 267 AFQTPGKLYLIL-DFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDL 325
Query: 270 KPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQ-IY 328
KPEN+L LDE + L DFGLSKQ +
Sbjct: 326 KPENIL-----------------------LDE-----------HGHIALTDFGLSKQPLD 351
Query: 329 QTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKIS 388
+ T + CGTV Y APE+V + + D W G ++Y +L G PF + +I
Sbjct: 352 GSKTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQIL 411
Query: 389 RGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKR 421
R + + +S A++ +R L + +P R
Sbjct: 412 RSKLGMP----ENLSPEAQSLLRALFKRNPQNR 440
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 139 bits (349), Expect = 1e-32
Identities = 116/381 (30%), Positives = 174/381 (45%), Gaps = 75/381 (19%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + +G+G F+KVY G +I + VAIKVI K Q+
Sbjct: 12 YEMGRLLGKGTFAKVYYG-----------KEIIGGEC--VAIKVINKDQVMK-------- 50
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
+ EQ+ +EI+I K+V NIV + ++ + + E + GGE+F +I K
Sbjct: 51 --RPGMMEQIKREISIMKLVRH-PNIVELKEVMATKTKIFFVMEFVKGGELFCKISKGK- 106
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
ED +R +QL +AV Y H G+ HRD+KPENLL L
Sbjct: 107 LHEDAARRYFQQLISAVDYCHSRGVSHRDLKPENLL-----------------------L 143
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLS---KQIYQTN-TKTPCGTVGYTAPEVVKDERY-SM 354
DE +K++DFGLS +QI Q T CGT Y APEV+K + Y
Sbjct: 144 DEN-----------GDLKISDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLKKKGYDGA 192
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+ D+W G VLY +L G PF DE + + KI R ++ F PW+ S A+ + KLL
Sbjct: 193 KADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRADFEF-PPWF---SPEARRLISKLL 248
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAYKKNASLLYS 474
VDP +R + +++ PWL P A + P + +++ + +N + S
Sbjct: 249 VVDPDRRISIPAIMRTPWLRKNFTPPLAFKIDEPICSQSSKNNEEEEEDGDCENQTEPIS 308
Query: 475 PA-------AVAMRDAFDVSN 488
P +M FD+S+
Sbjct: 309 PKFFNAFEFISSMSSGFDLSS 329
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 138 bits (347), Expect = 2e-32
Identities = 105/376 (27%), Positives = 168/376 (43%), Gaps = 60/376 (15%)
Query: 112 PEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPN 171
P + YTL +++G G F T C+ A+ + + A K I K++L N
Sbjct: 60 PMEDVKSSYTLGKELGRGQFGV-------THLCTQKATGL------QFACKTIAKRKLVN 106
Query: 172 TNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIF 231
E V +E+ I ++ NIV E + +++ EL AGGE+F
Sbjct: 107 KED-----------IEDVRREVQIMHHLTGQPNIVELKGAYEDKHSVHLVMELCAGGELF 155
Query: 232 GEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRS 291
I+ ++SE + ++R + + H +G++HRD+KPEN L L S
Sbjct: 156 DRIIAKGHYSERAAASLLRTIVQIIHTCHSMGVIHRDLKPENFL-------------LLS 202
Query: 292 SDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT--KTPCGTVGYTAPEVVKD 349
D+ S +K DFGLS Y+ K G+ Y APEV++
Sbjct: 203 KDENSP------------------LKATDFGLSV-FYKPGEVFKDIVGSAYYIAPEVLR- 242
Query: 350 ERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNC 409
+Y + D+W +G +LY +LCG PPF+ E + + I G+ F W IS AK+
Sbjct: 243 RKYGPEADIWSIGVMLYILLCGVPPFWAESENGIFNAILSGQVDFSSDPWPVISPQAKDL 302
Query: 410 VRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRK-AYKKN 468
VRK+L DP +R T+ Q+L PW+ P NA + K+ + + +K A +
Sbjct: 303 VRKMLNSDPKQRLTAAQVLNHPWIKEDGEAPDVPLDNAVMSRLKQFKAMNNFKKVALRVI 362
Query: 469 ASLLYSPAAVAMRDAF 484
A L + +++ F
Sbjct: 363 AGCLSEEEIMGLKEMF 378
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 137 bits (346), Expect = 3e-32
Identities = 85/263 (32%), Positives = 138/263 (52%), Gaps = 29/263 (11%)
Query: 174 KKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGE 233
KK +++ +S + + +E+ I K V E+I+ E+ K Y++ EL GE+
Sbjct: 145 KKVNKEKAGSSAVKLLEREVNILKSVKH-EHIIHLEQVFETPKKMYLVMELCEDGELKEI 203
Query: 234 IVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSD 293
+ + +FSE+ +R +I+ LA+A+ Y+H IVHRD+K EN++ + N + L
Sbjct: 204 LDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLN--- 260
Query: 294 DPSTKLDEGVFRPXXXXXXXXVVKLADFGLS---KQIYQTNTKTPCGTVGYTAPEVVKDE 350
+K+ DFGL+ + + + CGT Y APEV+
Sbjct: 261 ----------------------IKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAH 298
Query: 351 RYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCV 410
YS Q D+W +G V+Y +L G PPF + L E I +GE F W+ ISD AK+ +
Sbjct: 299 DYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVL 358
Query: 411 RKLLEVDPAKRYTSEQLLQDPWL 433
++L++VDPA R T+++LL + WL
Sbjct: 359 KQLMKVDPAHRITAKELLDNQWL 381
>At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 137 bits (346), Expect = 3e-32
Identities = 106/386 (27%), Positives = 176/386 (45%), Gaps = 60/386 (15%)
Query: 108 EDVFPEQTE--LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVII 165
E V +TE + Y+L +K+G+G F + + T+ KE A K I
Sbjct: 136 ESVLQRKTENFKEFYSLGRKLGQGQFGTTFLCVEKTTG-------------KEFACKSIA 182
Query: 166 KQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELL 225
K++L DE E V +EI I ++ N++S E +++ E
Sbjct: 183 KRKLLT-----DED------VEDVRREIQIMHHLAGHPNVISIKGAYEDVVAVHLVMECC 231
Query: 226 AGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNP 285
AGGE+F I++ +++E + + R + V+ H LG++HRD+KPEN LF
Sbjct: 232 AGGELFDRIIQRGHYTERKAAELTRTIVGVVEACHSLGVMHRDLKPENFLF--------- 282
Query: 286 KPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPC-GTVGYTAP 344
+ +D ++K DFGLS + T G+ Y AP
Sbjct: 283 ---VSKHED-------------------SLLKTIDFGLSMFFKPDDVFTDVVGSPYYVAP 320
Query: 345 EVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISD 404
EV++ +RY + D+W G ++Y +L G PPF+ E + E++ G+ F W IS+
Sbjct: 321 EVLR-KRYGPEADVWSAGVIVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISE 379
Query: 405 GAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHS-HKHSRK 463
AK+ VRK+L DP KR T+ Q+L PW+ P +A + K+ + +K +
Sbjct: 380 SAKDLVRKMLVRDPKKRLTAHQVLCHPWVQVDGVAPDKPLDSAVLSRMKQFSAMNKFKKM 439
Query: 464 AYKKNASLLYSPAAVAMRDAFDVSNA 489
A + A L +++ F++ +A
Sbjct: 440 ALRVIAESLSEEEIAGLKEMFNMIDA 465
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 137 bits (345), Expect = 4e-32
Identities = 96/322 (29%), Positives = 150/322 (45%), Gaps = 66/322 (20%)
Query: 114 QTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTN 173
+T + Y L + +GEG F+KV N NG + VAIKVI K
Sbjct: 25 RTRVGKYELGRTLGEGTFAKV----KFARNVENGDN---------VAIKVIDK------- 64
Query: 174 KKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGE 233
EK K Q+ +EI+ K++ N++ + S+ Y + E + GGE+F +
Sbjct: 65 ----EKVLKNKMIAQIKREISTMKLIKH-PNVIRMFEVMASKTKIYFVLEFVTGGELFDK 119
Query: 234 IVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSD 293
I ED +R +QL NAV Y H G+ HRD+KPENLL +
Sbjct: 120 ISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD---------------- 163
Query: 294 DPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN--TKTPCGTVGYTAPEVVKDER 351
+K++DFGLS Q + T CGT Y APEV+ ++
Sbjct: 164 ------------------ANGALKVSDFGLSALPQQEDGLLHTTCGTPNYVAPEVINNKG 205
Query: 352 Y-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCV 410
Y + D+W G +L+ ++ G+ PF D + L +KI + E+T PW+ S AK +
Sbjct: 206 YDGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFT-CPPWF---SASAKKLI 261
Query: 411 RKLLEVDPAKRYTSEQLLQDPW 432
+++L+ +PA R T +++++ W
Sbjct: 262 KRILDPNPATRITFAEVIENEW 283
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 137 bits (344), Expect = 5e-32
Identities = 97/324 (29%), Positives = 160/324 (48%), Gaps = 66/324 (20%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
EQ + +Y L++ IG+G +KV A ++ +EVAIK+I K QL
Sbjct: 52 EQPHVGNYRLLRTIGKGNSAKVKL-----------ARHILTG--REVAIKIIDKTQL--- 95
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
S+ +++ +E+ I K ++ NIV + E+EK Y++ E + GE+F
Sbjct: 96 ---------NPSSLQKLFREVRIMKGLNH-PNIVKLFEVIETEKTLYLVMEYASAGEVFD 145
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+V + E +R RQ+ +AV Y HQ IVHRD+K ENLL +
Sbjct: 146 YLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD--------------- 190
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-YQTNTKTPCGTVGYTAPEVVKDER 351
+K+ADFG S + + T CG+ Y APE+ + ++
Sbjct: 191 -------------------AEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKK 231
Query: 352 YS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCV 410
Y +VD+W +G +LYT++ G PF + L E++ RG+Y P++ +S ++ +
Sbjct: 232 YDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRV--PFY--MSTDCESIL 287
Query: 411 RKLLEVDPAKRYTSEQLLQDPWLN 434
R+ L ++PAKR T EQ+++D W+N
Sbjct: 288 RRFLVLNPAKRCTLEQIMKDKWIN 311
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 137 bits (344), Expect = 5e-32
Identities = 105/376 (27%), Positives = 167/376 (43%), Gaps = 60/376 (15%)
Query: 112 PEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPN 171
P + Y+L +++G G F T C+ A+ + A K I K++L N
Sbjct: 65 PMEDVKASYSLGKELGRGQFGV-------THLCTQKATG------HQFACKTIAKRKLVN 111
Query: 172 TNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIF 231
E V +E+ I ++ NIV E + +++ EL AGGE+F
Sbjct: 112 KED-----------IEDVRREVQIMHHLTGQPNIVELKGAYEDKHSVHLVMELCAGGELF 160
Query: 232 GEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRS 291
I+ ++SE + ++R + V H +G++HRD+KPEN L L +
Sbjct: 161 DRIIAKGHYSERAAASLLRTIVQIVHTCHSMGVIHRDLKPENFL-------------LLN 207
Query: 292 SDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT--KTPCGTVGYTAPEVVKD 349
D+ S +K DFGLS Y+ K G+ Y APEV+K
Sbjct: 208 KDENSP------------------LKATDFGLSV-FYKPGEVFKDIVGSAYYIAPEVLK- 247
Query: 350 ERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNC 409
+Y + D+W +G +LY +LCG PPF+ E + + I RG F W IS AK+
Sbjct: 248 RKYGPEADIWSIGVMLYILLCGVPPFWAESENGIFNAILRGHVDFSSDPWPSISPQAKDL 307
Query: 410 VRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRK-AYKKN 468
V+K+L DP +R T+ Q+L PW+ P NA + K+ + + +K A +
Sbjct: 308 VKKMLNSDPKQRLTAAQVLNHPWIKEDGEAPDVPLDNAVMSRLKQFKAMNNFKKVALRVI 367
Query: 469 ASLLYSPAAVAMRDAF 484
A L + +++ F
Sbjct: 368 AGCLSEEEIMGLKEMF 383
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 137 bits (344), Expect = 5e-32
Identities = 99/319 (31%), Positives = 160/319 (50%), Gaps = 70/319 (21%)
Query: 120 YTLIQKIGEGAFSKVY--RGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGD 177
Y LI+ IG+G F+KV + +P+ KEVAIK+I K QL
Sbjct: 151 YKLIKTIGKGNFAKVKLAKHLPTG---------------KEVAIKIIDKTQL-------- 187
Query: 178 EKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKY 237
+ +++ +E+ I K++ NIV E+EK Y+I E +GGE+F +V +
Sbjct: 188 ----NPGSLQKLFREVRIMKMLDH-PNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLH 242
Query: 238 TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPST 297
E +R RQ+ +AV+Y HQ I+HRD+K ENLL + +
Sbjct: 243 GRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLD-------------------S 283
Query: 298 KLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQ-TNTKTPCGTVGYTAPEVVKDERY-SMQ 355
+L+ +K+ADFG S + + T CG+ Y APE+ + ++Y +
Sbjct: 284 ELN---------------IKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPE 328
Query: 356 VDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLE 415
VD+W +G +LYT++ G PF + L E++ RG+Y P++ +S +N +RK L
Sbjct: 329 VDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRI--PFY--MSTDCENLLRKFLV 384
Query: 416 VDPAKRYTSEQLLQDPWLN 434
++PAKR + E ++ D W+N
Sbjct: 385 LNPAKRASLETIMGDKWMN 403
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 136 bits (343), Expect = 7e-32
Identities = 87/272 (31%), Positives = 134/272 (48%), Gaps = 36/272 (13%)
Query: 204 NIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLG 263
NI+ ++ E+++ Y++ EL GGE+F I+ F+E + V++ + + V+Y+H LG
Sbjct: 154 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 213
Query: 264 IVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGL 323
I HRD+KPENLL+ + P K + + DFGL
Sbjct: 214 ITHRDLKPENLLY----YHPGTDSK---------------------------IIITDFGL 242
Query: 324 S---KQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKI 380
+ K+ KT CGT Y APEV+ + Y+ VDMW +G + Y +L G PF D+
Sbjct: 243 ASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNR 302
Query: 381 DVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLP 440
L +I RG+Y++ W +S+ AK+ + +LL VDP R T+ Q L+ PW+ S
Sbjct: 303 TRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASS 362
Query: 441 SAD--HSNAPSTGEKRRHSHKHSRKAYKKNAS 470
S H + KR S S K+ + S
Sbjct: 363 SMKNLHRSISQNLLKRASSRCQSTKSAQSTRS 394
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 136 bits (343), Expect = 7e-32
Identities = 93/321 (28%), Positives = 155/321 (47%), Gaps = 64/321 (19%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
L +Y + + +G G+F+KV + +A +K VAIK++ + ++ N +
Sbjct: 16 LPNYRIGKTLGHGSFAKVKLALH------------VATGHK-VAIKILNRSKIKNMGIE- 61
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
+V +EI I + + +I+ + E+ Y++ E + GE+F IV+
Sbjct: 62 ----------IKVQREIKILRFLMH-PHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVE 110
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
ED +RH+ +Q+ + V+Y H+ IVHRD+KPEN+L +
Sbjct: 111 KGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLD------------------- 151
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPEVVKDERYSMQ 355
+K+ DFGLS ++ + KT CG+ Y APEV+ + Y
Sbjct: 152 ---------------SQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPD 196
Query: 356 VDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLE 415
VD+W G +LY +LCG PF DE I + EKI RG YT + +S A++ + ++L
Sbjct: 197 VDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLP----NHLSHFARDLIPRMLM 252
Query: 416 VDPAKRYTSEQLLQDPWLNSY 436
VDP R + ++ Q PW N++
Sbjct: 253 VDPTMRISITEIRQHPWFNNH 273
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 136 bits (342), Expect = 9e-32
Identities = 99/328 (30%), Positives = 163/328 (49%), Gaps = 66/328 (20%)
Query: 107 PEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIK 166
P+ + + +Y +++ +GEG+F KV +T+ ++VA+K+I K
Sbjct: 42 PKSSLADGAHIGNYQIVKTLGEGSFGKVKLAYHTTTG-------------QKVALKIINK 88
Query: 167 QQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLA 226
+ L ++ +G ++ +EI+ +++ +I+ D +S+ ++ E A
Sbjct: 89 KVLAKSDMQG-----------RIEREISYLRLLRH-PHIIKLYDVIKSKDEIIMVIEY-A 135
Query: 227 GGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPK 286
G E+F IV+ SE +R +Q+ +AV+Y H+ IVHRD+KPENLL
Sbjct: 136 GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLL----------- 184
Query: 287 PKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPE 345
LDE + VK+ADFGLS + N KT CG+ Y APE
Sbjct: 185 ------------LDEHLN-----------VKIADFGLSNIMTDGNFLKTSCGSPNYAAPE 221
Query: 346 VVKDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISD 404
V+ + Y+ +VD+W G +LY +LC PF DE I VL + IS G YT + +S
Sbjct: 222 VISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPK----FLSP 277
Query: 405 GAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
GA ++++L V+P R + +++QD W
Sbjct: 278 GAAGLIKRMLIVNPLNRISIHEIMQDDW 305
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 136 bits (342), Expect = 9e-32
Identities = 99/318 (31%), Positives = 153/318 (47%), Gaps = 67/318 (21%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + +G GAF+KV+ + S VA+K++ K++L
Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQS-------------VAVKILNKKKLLTN------- 60
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
+ A + +EI+I + +S NIV + ++ + E + GGE+F +I K+
Sbjct: 61 ---PALANNIKREISIMRRLSH-PNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGR 116
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
SEDLSR +QL +AV Y H G+ HRD+KPENLL +
Sbjct: 117 LSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLL-----------------------I 153
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK----TPCGTVGYTAPEVVKDERYS-M 354
DE +K++DFGLS Q T CGT Y APE++ + Y
Sbjct: 154 DEN-----------GNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEGA 202
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+VD+W G VL+ ++ G+ PF D + + +KI +GEY F P W +S K V +LL
Sbjct: 203 KVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRF--PRW--MSPDLKRFVSRLL 258
Query: 415 EVDPAKRYTSEQLLQDPW 432
+++P R T +++L+DPW
Sbjct: 259 DINPETRITIDEILKDPW 276
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 135 bits (341), Expect = 1e-31
Identities = 105/329 (31%), Positives = 158/329 (47%), Gaps = 73/329 (22%)
Query: 113 EQTELK----DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQ 168
EQ +L+ Y + + +G+G F KVY G T+ + VAIK+I K Q
Sbjct: 4 EQQQLRVLFAKYEMGRLLGKGTFGKVYYGKEITTG-------------ESVAIKIINKDQ 50
Query: 169 LPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGG 228
+ + EQ+ +EI+I ++V NIV + ++ + I E + GG
Sbjct: 51 VK-----------REGMMEQIKREISIMRLVRH-PNIVELKEVMATKTKIFFIMEYVKGG 98
Query: 229 EIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPK 288
E+F +IVK ED +R +QL +AV + H G+ HRD+KPENLL
Sbjct: 99 ELFSKIVKGK-LKEDSARKYFQQLISAVDFCHSRGVSHRDLKPENLL------------- 144
Query: 289 LRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLS---KQIYQTN-TKTPCGTVGYTAP 344
+DE +K++DFGLS +QI Q T CGT Y AP
Sbjct: 145 ----------VDEN-----------GDLKVSDFGLSALPEQILQDGLLHTQCGTPAYVAP 183
Query: 345 EVVKDERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQIS 403
EV++ + Y + D+W G +LY +L GF PF DE + + KI + E+ + PW+ S
Sbjct: 184 EVLRKKGYDGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEY-PPWF---S 239
Query: 404 DGAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
+K + KLL VDP KR + +++ PW
Sbjct: 240 PESKRLISKLLVVDPNKRISIPAIMRTPW 268
>At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 560
Score = 135 bits (341), Expect = 1e-31
Identities = 102/375 (27%), Positives = 166/375 (44%), Gaps = 58/375 (15%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
YTL +++G G F Y C++ + + A K I+K++L
Sbjct: 63 YTLGRELGRGEFGVTYL-------CTDKETDDV------FACKSILKKKLRTA------- 102
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
E V +E+ I + + N+V+ + E E +++ EL GGE+F IV +
Sbjct: 103 ----VDIEDVRREVEIMRHMPEHPNVVTLKETYEDEHAVHLVMELCEGGELFDRIVARGH 158
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
++E + V + + V+ H+ G++HRD+KPEN LF N K
Sbjct: 159 YTERAAAAVTKTIMEVVQVCHKHGVMHRDLKPENFLFG------NKKE------------ 200
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPC-GTVGYTAPEVVKDERYSMQVDM 358
+K DFGLS G+ Y APEV+K Y +VD+
Sbjct: 201 -------------TAPLKAIDFGLSVFFKPGERFNEIVGSPYYMAPEVLK-RNYGPEVDI 246
Query: 359 WGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDP 418
W G +LY +LCG PPF+ E + + I R F R W ++S+ AK+ +RK+L+ D
Sbjct: 247 WSAGVILYILLCGVPPFWAETEQGVAQAIIRSVLDFRRDPWPKVSENAKDLIRKMLDPDQ 306
Query: 419 AKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKR-RHSHKHSRKAYKKNASLLYSPAA 477
+R T++Q+L PWL + P+ K+ +K ++A + A L A
Sbjct: 307 KRRLTAQQVLDHPWLQNAKTAPNVSLGETVRARLKQFTVMNKLKKRALRVIAEHLSDEEA 366
Query: 478 VAMRDAFDVSNAVQR 492
+R+ F + + QR
Sbjct: 367 SGIREGFQIMDTSQR 381
>At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 134 bits (338), Expect = 3e-31
Identities = 100/348 (28%), Positives = 157/348 (44%), Gaps = 67/348 (19%)
Query: 106 EPEDVFPEQT-ELKDY-TLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKV 163
+ E V +T LK+Y L K+G G F + + + +E A K
Sbjct: 116 QAESVLKTKTGHLKEYYNLGSKLGHGQFGTTFVCVEKGTG-------------EEYACKS 162
Query: 164 IIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQE 223
I K++L N E V +EI I K + N++S E +++ E
Sbjct: 163 IPKRKLENEED-----------VEDVRREIEIMKHLLGQPNVISIKGAYEDSVAVHMVME 211
Query: 224 LLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIP 283
L GGE+F IV+ ++SE + H+ + + V+ H LG++HRD+KPEN LF
Sbjct: 212 LCRGGELFDRIVERGHYSERKAAHLAKVILGVVQTCHSLGVMHRDLKPENFLFV------ 265
Query: 284 NPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPC-GTVGYT 342
+DD + L K DFGLS + T G+ Y
Sbjct: 266 --------NDDEDSPL-----------------KAIDFGLSMFLKPGENFTDVVGSPYYI 300
Query: 343 APEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQI 402
APEV+ ++ Y + D+W G ++Y +L G PF+ E + + ++ GE W Q+
Sbjct: 301 APEVL-NKNYGPEADIWSAGVMIYVLLSGSAPFWGETEEEIFNEVLEGELDLTSDPWPQV 359
Query: 403 SDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPST 450
S+ AK+ +RK+LE +P +R T++Q+L PW+ D NAP T
Sbjct: 360 SESAKDLIRKMLERNPIQRLTAQQVLCHPWIR--------DEGNAPDT 399
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 134 bits (337), Expect = 4e-31
Identities = 96/335 (28%), Positives = 152/335 (44%), Gaps = 74/335 (22%)
Query: 116 ELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKK 175
+LKD + +GEG+FS + + SN + + +K+I K+ NT K
Sbjct: 426 DLKD----KPLGEGSFSICRKCVHKKSN-------------QALQVKIISKRMEANTQK- 467
Query: 176 GDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV 235
EI K+ NIV + + + +++ ELL GGE+F +
Sbjct: 468 ----------------EITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFDALR 511
Query: 236 KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDP 295
K +FSE + +++R+L +A+ +MH LG+VHRD+KPENLLF D
Sbjct: 512 KKKHFSETEASYIMRKLVSALSHMHDLGVVHRDLKPENLLF----------------TDE 555
Query: 296 STKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN--TKTPCGTVGYTAPEVVKDERYS 353
+ L+ +K+ DFG ++ N KTPC T+ PE++ Y
Sbjct: 556 NDNLE---------------IKIIDFGFARLKPPDNQPLKTPCFTLHSCRPELLNQNGYD 600
Query: 354 MQVDMWGVGCVLYTVLCGFPPFFDEKIDV-------LTEKISRGEYTFLRPWWDQISDGA 406
D+W +G +LYT+L G PF + + +KI +G+++F W +S A
Sbjct: 601 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA 660
Query: 407 KNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPS 441
K+ ++ LL VDP KR L + WL L S
Sbjct: 661 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSS 695
Score = 94.7 bits (234), Expect = 3e-19
Identities = 82/314 (26%), Positives = 141/314 (44%), Gaps = 59/314 (18%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
E+ ++++ L++ +G GA+ KV+ + S G K A+KV+ K +
Sbjct: 42 EKVGIENFELLKVLGTGAYGKVFL-VRKISGHDTG---------KLYAMKVLKKATIVQK 91
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
K + T T QVL+ I + + FQ K + I+ + + GGE+F
Sbjct: 92 AKTTEH----TRTERQVLEHIRQSPFL-----VTLHYAFQTETKLHLIL-DYINGGELFT 141
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+ + F+E + + ++ A++++H+LGI++RDIK EN+L +
Sbjct: 142 HLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLD--------------- 186
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP---CGTVGYTAPEVVK- 348
V L DFGLSK+ T+ CGT+ Y AP++V+
Sbjct: 187 -------------------SNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRG 227
Query: 349 -DERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAK 407
D + VD W +G ++Y +L G PF + +ISR P+ ++S AK
Sbjct: 228 GDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAK 287
Query: 408 NCVRKLLEVDPAKR 421
+ +++LL DP KR
Sbjct: 288 DLIQRLLMKDPKKR 301
>At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 582
Score = 134 bits (337), Expect = 4e-31
Identities = 80/260 (30%), Positives = 130/260 (49%), Gaps = 37/260 (14%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSR 246
E V +E+ I + + NIVSF + E + Y++ E+ GGE+F IV +++E +
Sbjct: 109 EDVRREVEIMRCLPKHPNIVSFKEAFEDKDAVYLVMEICEGGELFDRIVSRGHYTERAAA 168
Query: 247 HVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRP 306
V + + VK H+ G++HRD+KPEN LF S+ + +L
Sbjct: 169 SVAKTILEVVKVCHEHGVIHRDLKPENFLF--------------SNGTETAQL------- 207
Query: 307 XXXXXXXXVVKLADFGLS---KQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGC 363
K DFGLS K + N G+ Y APEV++ Y ++D+W G
Sbjct: 208 ----------KAIDFGLSIFFKPAQRFNEIV--GSPYYMAPEVLR-RNYGPEIDVWSAGV 254
Query: 364 VLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYT 423
+LY +LCG PPF+ E + + I RG F R W ++S AK V+ +L+ +P R T
Sbjct: 255 ILYILLCGVPPFWAETEEGIAHAIVRGNIDFERDPWPKVSHEAKELVKNMLDANPYSRLT 314
Query: 424 SEQLLQDPWLNSYDCLPSAD 443
+++L+ PW+ + + P+ +
Sbjct: 315 VQEVLEHPWIRNAERAPNVN 334
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 133 bits (335), Expect = 6e-31
Identities = 105/339 (30%), Positives = 159/339 (45%), Gaps = 69/339 (20%)
Query: 103 PQEEPEDVFPEQTELKDYTL-IQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAI 161
P+E D F + +Y + +K+GEG+F+KV G+ + ++VAI
Sbjct: 45 PRERLRD-FQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTG-------------EKVAI 90
Query: 162 KVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYII 221
KVI K++ K D K E ++++ H NI +D E+E YY++
Sbjct: 91 KVIDKKRA-----KKDTYVTKNLRREGQIQQMIRHP------NITQLLDILETENSYYLV 139
Query: 222 QELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDF 281
EL GG + +I + E +R IRQL +AV+++H+ G+VHRD+K ENLL
Sbjct: 140 MELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLL------ 193
Query: 282 IPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI----YQTNTKTPCG 337
LDE +KL DFGLS Y T CG
Sbjct: 194 -----------------LDE-----------DNNIKLIDFGLSNCAGILGYSDPFSTQCG 225
Query: 338 TVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDE--KIDVLTEKISRGEYTFL 395
+ Y APE++ ++Y ++D+W +G +Y +L G PF E + L +K+ E +
Sbjct: 226 SPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKE---M 282
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLN 434
P Q+S GA + +R LLE DP KR +Q L + WLN
Sbjct: 283 NPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWLN 321
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 133 bits (335), Expect = 6e-31
Identities = 104/332 (31%), Positives = 154/332 (46%), Gaps = 72/332 (21%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + +G GAF+KVY G + + S VAIKV+ KQ+L G+
Sbjct: 22 YEVGKLVGCGAFAKVYHGRSTATGQS-------------VAIKVVSKQRLQKGGLNGN-- 66
Query: 180 NGKTSTAEQVLKEIAI-HKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
+ +EIAI H++ +IV + ++ + + E GGE+F ++ K
Sbjct: 67 ---------IQREIAIMHRL--RHPSIVRLFEVLATKSKIFFVMEFAKGGELFAKVSKGR 115
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
F EDLSR +QL +AV Y H GI HRD+KPENLL + K
Sbjct: 116 -FCEDLSRRYFQQLISAVGYCHSRGIFHRDLKPENLLLD-------------------EK 155
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN----TKTPCGTVGYTAPEVVKDERY-S 353
LD +K++DFGLS Q T CGT Y APEV+ + Y
Sbjct: 156 LD---------------LKISDFGLSALTDQIRPDGLLHTLCGTPAYVAPEVLAKKGYDG 200
Query: 354 MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKL 413
++D+W G +L+ + G+ PF D + V+ KI +GE+ P W S + + +L
Sbjct: 201 AKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRI--PKW--TSPDLRRLLTRL 256
Query: 414 LEVDPAKRYTSEQLLQDPWL-NSYDCLPSADH 444
L+ +P R T E+++ DPW YD S H
Sbjct: 257 LDTNPQTRITIEEIIHDPWFKQGYDDRMSKFH 288
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 133 bits (335), Expect = 6e-31
Identities = 100/318 (31%), Positives = 150/318 (46%), Gaps = 69/318 (21%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + +G G F+KVY N G K VA+KV+ G EK
Sbjct: 24 YELGRLLGHGTFAKVYHA----RNIQTG---------KSVAMKVV-----------GKEK 59
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
K +Q+ +EI++ ++V NIV + S+ Y EL+ GGE+F ++ K
Sbjct: 60 VVKVGMVDQIKREISVMRMVKH-PNIVELHEVMASKSKIYFAMELVRGGELFAKVAKGR- 117
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
ED++R +QL +AV + H G+ HRD+KPENLL +
Sbjct: 118 LREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLLD---------------------- 155
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLS---KQIYQTN-TKTPCGTVGYTAPEVVKDERY-SM 354
+EG +K+ DFGLS + + Q T CGT Y APEV+ + Y
Sbjct: 156 EEG------------NLKVTDFGLSAFTEHLKQDGLLHTTCGTPAYVAPEVILKKGYDGA 203
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+ D+W G +L+ +L G+ PF D+ + + KI RG+ F P W +S A+ V KLL
Sbjct: 204 KADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGD--FKCPGW--LSSDARRLVTKLL 259
Query: 415 EVDPAKRYTSEQLLQDPW 432
+ +P R T E+++ PW
Sbjct: 260 DPNPNTRITIEKVMDSPW 277
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 133 bits (335), Expect = 6e-31
Identities = 110/351 (31%), Positives = 163/351 (46%), Gaps = 75/351 (21%)
Query: 89 EENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGA 148
E++ ES T + +F + Y L + +G GAF+KVY+ + NG
Sbjct: 3 EDSNSSESIIVNVTGDDNKSALFGK------YDLGKLLGSGAFAKVYQA----EDLQNGG 52
Query: 149 SSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSF 208
SV AIKV+ K++L K+G T+ V +EI++ + + +IV
Sbjct: 53 ESV--------AIKVVQKKRL---------KDGLTA---HVKREISVMRRLRH-PHIVLL 91
Query: 209 IDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRD 268
+ ++ Y + EL GGE+F + F+E LSR RQL +AV+Y H G+ HRD
Sbjct: 92 SEVLATKTKIYFVMELAKGGELFSRVTS-NRFTESLSRKYFRQLISAVRYCHARGVFHRD 150
Query: 269 IKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIY 328
+KPENLL LDE +K++DFGLS
Sbjct: 151 LKPENLL-----------------------LDEN-----------RDLKVSDFGLSAMKE 176
Query: 329 QTN----TKTPCGTVGYTAPEVVKDERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVL 383
Q + T CGT Y APE++ + Y + D+W G VL+ + G+ PF D I L
Sbjct: 177 QIHPDGMLHTLCGTPAYVAPELLLKKGYDGSKADIWSCGVVLFLLNAGYLPFRDPNIMGL 236
Query: 384 TEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLN 434
KI + +Y P W S + +R+LLE +P R T E++L+DPW N
Sbjct: 237 YRKIHKAQYKL--PDW--TSSDLRKLLRRLLEPNPELRITVEEILKDPWFN 283
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 132 bits (333), Expect = 1e-30
Identities = 90/305 (29%), Positives = 144/305 (46%), Gaps = 34/305 (11%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSR 246
E V +E+ I K + NIVS D E + +I+ EL GGE+F IV +++E +
Sbjct: 100 EDVRREVEIMKHMPRHPNIVSLKDAFEDDDAVHIVMELCEGGELFDRIVARGHYTERAAA 159
Query: 247 HVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRP 306
V++ + V+ H+ G++HRD+KPEN LF N K
Sbjct: 160 AVMKTILEVVQICHKHGVMHRDLKPENFLFA------NKKE------------------- 194
Query: 307 XXXXXXXXVVKLADFGLSKQIYQ-TNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVL 365
+K DFGLS G+ Y APEV++ Y +VD+W G +L
Sbjct: 195 ------TSALKAIDFGLSVFFKPGEGFNEIVGSPYYMAPEVLR-RNYGPEVDIWSAGVIL 247
Query: 366 YTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSE 425
Y +LCG PPF+ E + + I R F R W ++S+ AK+ VRK+LE DP KR ++
Sbjct: 248 YILLCGVPPFWAETEQGVAQAIIRSVIDFKRDPWPRVSETAKDLVRKMLEPDPKKRLSAA 307
Query: 426 QLLQDPWLNSYDCLPSADHSNAPSTGEKR-RHSHKHSRKAYKKNASLLYSPAAVAMRDAF 484
Q+L+ W+ + P+ K+ +K ++A + A L +++AF
Sbjct: 308 QVLEHSWIQNAKKAPNVSLGETVKARLKQFSVMNKLKKRALRVIAEHLSVEEVAGIKEAF 367
Query: 485 DVSNA 489
++ ++
Sbjct: 368 EMMDS 372
>At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 530
Score = 132 bits (333), Expect = 1e-30
Identities = 96/327 (29%), Positives = 152/327 (46%), Gaps = 60/327 (18%)
Query: 112 PEQTELKD-YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLP 170
P E+K Y L +++G G F Y C+ + I A K I+K++L
Sbjct: 45 PTGHEIKQKYKLGRELGRGEFGVTYL-------CTEIETGEI------FACKSILKKKL- 90
Query: 171 NTNKKGDEKNGKTST-AEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGE 229
KTS E V +E+ I + + NIV+ + E +K +++ EL GGE
Sbjct: 91 -----------KTSIDIEDVKREVEIMRQMPEHPNIVTLKETYEDDKAVHLVMELCEGGE 139
Query: 230 IFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKL 289
+F IV +++E + VI+ + V+ H+ G++HRD+KPEN LF N K
Sbjct: 140 LFDRIVARGHYTERAAASVIKTIIEVVQMCHKHGVMHRDLKPENFLFA------NKKE-- 191
Query: 290 RSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPC-GTVGYTAPEVVK 348
+K DFGLS G+ Y APEV++
Sbjct: 192 -----------------------TASLKAIDFGLSVFFKPGERFNEIVGSPYYMAPEVLR 228
Query: 349 DERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKN 408
Y ++D+W G +LY +LCG PPF+ E + + I + F R W ++SD AK+
Sbjct: 229 -RSYGQEIDIWSAGVILYILLCGVPPFWAETEHGVAKAILKSVIDFKRDPWPKVSDNAKD 287
Query: 409 CVRKLLEVDPAKRYTSEQLLQDPWLNS 435
++K+L DP +R T++Q+L PW+ +
Sbjct: 288 LIKKMLHPDPRRRLTAQQVLDHPWIQN 314
>HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 424
Score = 132 bits (332), Expect = 1e-30
Identities = 105/355 (29%), Positives = 159/355 (44%), Gaps = 95/355 (26%)
Query: 108 EDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQ 167
ED++ +EL +GEGA++KV GA S+ Q KE A+K+I KQ
Sbjct: 45 EDMYKLTSEL--------LGEGAYAKV-----------QGAVSL--QNGKEYAVKIIEKQ 83
Query: 168 QLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAG 227
+ +V +E+ +NI+ I+F E + +Y++ E L G
Sbjct: 84 A--------------GHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQG 129
Query: 228 GEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKP 287
G I I K +F+E + V+R +A A+ ++H GI HRD+KPEN+L E + +
Sbjct: 130 GSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCESPEKV----- 184
Query: 288 KLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT---------KTPCGT 338
VK+ DF L + N+ TPCG+
Sbjct: 185 --------------------------SPVKICDFDLGSGMKLNNSCTPITTPELTTPCGS 218
Query: 339 VGYTAPEVVK---DER--YSMQVDMWGVGCVLYTVLCGFPPFFD--------EKIDV--- 382
Y APEVV+ D+ Y + D+W +G VLY +L G+PPF ++ +V
Sbjct: 219 AEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRV 278
Query: 383 ----LTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
L E I G+Y F W IS AK+ + KLL D +R ++ Q+LQ PW+
Sbjct: 279 CQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWV 333
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 132 bits (332), Expect = 1e-30
Identities = 97/331 (29%), Positives = 161/331 (48%), Gaps = 66/331 (19%)
Query: 104 QEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKV 163
+EE E+ + Y L + +G+G V G+ +C G ++VAIK+
Sbjct: 35 EEEAEERGRHAQYVGPYRLEKTLGKGQTGLVKLGV----HCITG---------QKVAIKI 81
Query: 164 IIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQE 223
+ +++L S +V +EIAI K++ +++ D E++KY Y++ E
Sbjct: 82 VNREKLSE------------SVLMKVEREIAILKLIEH-PHVLKLHDVYENKKYLYLVLE 128
Query: 224 LLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIP 283
++GGE+F +VK + +R RQ+ +A+ + H I HRD+KPENLL
Sbjct: 129 HVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLL-------- 180
Query: 284 NPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGL-SKQIYQTNTKTPCGTVGYT 342
LDE +++ADFG+ S Q+ + +T CG+ Y
Sbjct: 181 ---------------LDE-----------KNNIRIADFGMASLQVGDSLLETSCGSPHYA 214
Query: 343 APEVVKDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQ 401
PEV+K E+Y + DMW G +L+ +L G PF D+ + L EK+ RG F P +
Sbjct: 215 CPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRG--VFHMPHF-- 270
Query: 402 ISDGAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
I ++ +R ++EV+P KR + EQ+ + PW
Sbjct: 271 IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 301
>At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 556
Score = 132 bits (332), Expect = 1e-30
Identities = 105/369 (28%), Positives = 165/369 (44%), Gaps = 62/369 (16%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
YTL +K+G+G F Y C+ AS V + A K I K++L +
Sbjct: 97 YTLSRKLGQGQFGTTYL-------CTEIASGV------DYACKSISKRKLISKED----- 138
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
E V +EI I ++ +IV+ E Y +I+ EL AGGE+F I++ +
Sbjct: 139 ------VEDVRREIQIMHHLAGHGSIVTIKGAYEDSLYVHIVMELCAGGELFDRIIQRGH 192
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
+SE + + + + V+ H LG++HRD+KPEN L + DD S
Sbjct: 193 YSERKAAELTKIIVGVVEACHSLGVMHRDLKPENFLL------------VNKDDDFS--- 237
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPC-GTVGYTAPEVVKDERYSMQVDM 358
+K DFGLS T G+ Y APEV+ +RY + D+
Sbjct: 238 ----------------LKAIDFGLSVFFKPGQIFTDVVGSPYYVAPEVLL-KRYGPEADV 280
Query: 359 WGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDP 418
W G +LY +L G PPF+ E + + + +G F W ISD AK+ +R++L P
Sbjct: 281 WTAGVILYILLSGVPPFWAETQQGIFDAVLKGYIDFESDPWPVISDSAKDLIRRMLSSKP 340
Query: 419 AKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRH---SHKHSRKAYKKNASLLYSP 475
A+R T+ ++L+ PW+ P D + P+ + + +K + A K A L
Sbjct: 341 AERLTAHEVLRHPWICENGVAP--DRALDPAVLSRLKQFSAMNKLKKMALKVIAESLSEE 398
Query: 476 AAVAMRDAF 484
+R+ F
Sbjct: 399 EIAGLREMF 407
>At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 529
Score = 132 bits (331), Expect = 2e-30
Identities = 92/300 (30%), Positives = 136/300 (44%), Gaps = 34/300 (11%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSR 246
E V +E+ I +S NIV E +I EL GGE+F I+ +SE +
Sbjct: 121 EDVRREVQIMHHLSGHRNIVDLKGAYEDRHSVNLIMELCEGGELFDRIISKGLYSERAAA 180
Query: 247 HVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRP 306
+ RQ+ V H +G++HRD+KPEN LF S D+ S
Sbjct: 181 DLCRQMVMVVHSCHSMGVMHRDLKPENFLF-------------LSKDENSP--------- 218
Query: 307 XXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVL 365
+K DFGLS + K G+ Y APEV+K Y + D+W G +L
Sbjct: 219 ---------LKATDFGLSVFFKPGDKFKDLVGSAYYVAPEVLK-RNYGPEADIWSAGVIL 268
Query: 366 YTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSE 425
Y +L G PPF+ E + + I +G+ F W +SDGAK+ VRK+L+ DP R T+
Sbjct: 269 YILLSGVPPFWGENETGIFDAILQGQLDFSADPWPALSDGAKDLVRKMLKYDPKDRLTAA 328
Query: 426 QLLQDPWLNSYDCLPSADHSNAPSTGEKR-RHSHKHSRKAYKKNASLLYSPAAVAMRDAF 484
++L PW+ NA + K+ R +K + A K A L + +++ F
Sbjct: 329 EVLNHPWIREDGEASDKPLDNAVLSRMKQFRAMNKLKKMALKVIAENLSEEEIIGLKEMF 388
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 132 bits (331), Expect = 2e-30
Identities = 86/282 (30%), Positives = 136/282 (47%), Gaps = 45/282 (15%)
Query: 157 KEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEK 216
+EVA+KVI K ++ + + E V +E+ I + +S +N+V F D E
Sbjct: 171 QEVAVKVIPKSKMTSA-----------ISIEDVRREVKILRALSGHQNLVQFYDAFEDNA 219
Query: 217 YYYIIQELLAGGEIFGEIV-KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLL 275
YI+ EL GGE+ I+ + +SED ++ V+ Q+ N V + H G+VHRD+KPEN L
Sbjct: 220 NVYIVMELCGGGELLDRILARGGKYSEDDAKAVLIQILNVVAFCHLQGVVHRDLKPENFL 279
Query: 276 FEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP 335
+ T +E ++K+ DFGLS +
Sbjct: 280 Y--------------------TSKEEN-----------SMLKVIDFGLSDFVRPDERLND 308
Query: 336 C-GTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTF 394
G+ Y APEV+ Y+ + D+W +G + Y +LCG PF+ + + + + +F
Sbjct: 309 IVGSAYYVAPEVLH-RSYTTEADVWSIGVIAYILLCGSRPFWARTESGIFRAVLKADPSF 367
Query: 395 LRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSY 436
P W +S AK+ V++LL DP KR T+ Q L PW+ Y
Sbjct: 368 DEPPWPSLSFEAKDFVKRLLYKDPRKRMTASQALMHPWIAGY 409
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 132 bits (331), Expect = 2e-30
Identities = 88/281 (31%), Positives = 143/281 (50%), Gaps = 52/281 (18%)
Query: 158 EVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKY 217
+VAIK++ ++++ N + E+V +EI I ++ +I+ + E+
Sbjct: 44 KVAIKILNRRKIKNMEME-----------EKVRREIKILRLFMH-PHIIRLYEVIETPTD 91
Query: 218 YYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFE 277
Y++ E + GE+F IV+ ED +R+ +Q+ + V+Y H+ +VHRD+KPENLL +
Sbjct: 92 IYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLD 151
Query: 278 PIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPC 336
+K + VK+ADFGLS + + KT C
Sbjct: 152 -------------------SKCN---------------VKIADFGLSNIMRDGHFLKTSC 177
Query: 337 GTVGYTAPEVVKDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFL 395
G+ Y APEV+ + Y+ +VD+W G +LY +LCG PF DE I L +KI G YT
Sbjct: 178 GSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLP 237
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSY 436
+S GA++ + ++L VDP KR T ++ Q PW ++
Sbjct: 238 ----SHLSPGARDLIPRMLVVDPMKRVTIPEIRQHPWFQAH 274
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 131 bits (330), Expect = 2e-30
Identities = 98/317 (30%), Positives = 153/317 (47%), Gaps = 66/317 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y +I+ +G+G F+KV I + +EVAIKVI K QL
Sbjct: 98 YKIIKTLGKGNFAKVKLAIHVPTG-------------REVAIKVIDKTQL---------- 134
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
TS +++ +E+ I K+++ NIV ESE+ Y++ E + GE+F +VK
Sbjct: 135 --NTSARQKLYREVKIMKLLNH-PNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGR 191
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
E +R + RQL +A++Y H +VHRD+K ENLL L
Sbjct: 192 MRERDARVIFRQLVSAIQYCHSKFVVHRDLKAENLL-----------------------L 228
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQI-YQTNTKTPCGTVGYTAPEVVKDERYS-MQVD 357
D+ + +K+ADFG +T CG+ Y APE+ +Y+ +VD
Sbjct: 229 DQHM-----------NIKIADFGFGNTFDPNAQLETFCGSPPYAAPELFMGRKYAGPEVD 277
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
W +G VLYT++ G PF + L E++ RG+Y P++ IS +N +RK L ++
Sbjct: 278 AWSLGVVLYTLVSGSLPFDGGTLKELRERVLRGKYRV--PYY--ISMDCENLMRKFLVLN 333
Query: 418 PAKRYTSEQLLQDPWLN 434
PAKR + ++ D W+N
Sbjct: 334 PAKRTSLSAVMSDKWIN 350
>At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 646
Score = 131 bits (329), Expect = 3e-30
Identities = 109/425 (25%), Positives = 183/425 (42%), Gaps = 72/425 (16%)
Query: 81 QGKDGTSQEENTYDESSDATTTPQE------------EPEDVFPEQTE--LKDYTLIQKI 126
+ K T++ E T + + PQ+ E V +TE + Y+L +K+
Sbjct: 133 ESKPETTKPETTSETKPETKAEPQKPKHMRRVSSAGLRTESVLQRKTENFKEFYSLGRKL 192
Query: 127 GEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTA 186
G+G F + + + E A K I K++L DE
Sbjct: 193 GQGQFGTTFLCLEKGTG-------------NEYACKSISKRKLLT-----DED------V 228
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSR 246
E V +EI I ++ N++S E +++ EL +GGE+F I++ +++E +
Sbjct: 229 EDVRREIQIMHHLAGHPNVISIKGAYEDVVAVHLVMELCSGGELFDRIIQRGHYTERKAA 288
Query: 247 HVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRP 306
+ R + ++ H LG++HRD+KPEN LF R D
Sbjct: 289 ELARTIVGVLEACHSLGVMHRDLKPENFLFVS-----------REEDS------------ 325
Query: 307 XXXXXXXXVVKLADFGLSKQIYQTNTKTPC-GTVGYTAPEVVKDERYSMQVDMWGVGCVL 365
++K DFGLS T G+ Y APEV++ +RY + D+W G ++
Sbjct: 326 --------LLKTIDFGLSMFFKPDEVFTDVVGSPYYVAPEVLR-KRYGPESDVWSAGVIV 376
Query: 366 YTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSE 425
Y +L G PPF+ E + E++ G+ F W IS+ AK+ VRK+L DP +R T+
Sbjct: 377 YILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAKDLVRKMLVRDPKRRLTAH 436
Query: 426 QLLQDPWLNSYDCLPSADHSNAPSTGEKRRHS-HKHSRKAYKKNASLLYSPAAVAMRDAF 484
Q+L PW+ P +A + K+ + +K + A + A L ++ F
Sbjct: 437 QVLCHPWVQIDGVAPDKPLDSAVLSRMKQFSAMNKFKKMALRVIAESLSEEEIAGLKQMF 496
Query: 485 DVSNA 489
+ +A
Sbjct: 497 KMIDA 501
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 130 bits (328), Expect = 4e-30
Identities = 93/317 (29%), Positives = 156/317 (48%), Gaps = 66/317 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + +G+G V G ++C G ++VAIK++ K++L
Sbjct: 47 YKLEKTLGKGQTGLVKTG----THCITG---------RKVAIKIVNKEKLSE-------- 85
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
S ++V +EIAI K++ +++ D E++KY Y++ E ++GGE+F +V+
Sbjct: 86 ----SVLQKVEREIAIMKLIEH-PHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGR 140
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
+R RQ+ +A+ + H I HRD+KPENLL L
Sbjct: 141 LMSKEARKFFRQIISALDFCHAHNICHRDLKPENLL-----------------------L 177
Query: 300 DEGVFRPXXXXXXXXVVKLADFGL-SKQIYQTNTKTPCGTVGYTAPEVVKDERYS-MQVD 357
DE +K+ADFG+ S Q+ + +T CG+ Y PEV++ E+Y + D
Sbjct: 178 DE-----------RNNIKVADFGMASLQVEGSMLETSCGSPHYACPEVIRGEKYDGRKAD 226
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G PF D+ + L EK+ RG F P + + ++ +R ++EVD
Sbjct: 227 VWSCGVILYALLVGALPFDDDNLRNLLEKVKRG--VFHIPHF--VPADVQSLLRAMIEVD 282
Query: 418 PAKRYTSEQLLQDPWLN 434
P KRY+ + + PW++
Sbjct: 283 PGKRYSLADVFKHPWVS 299
>At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 544
Score = 130 bits (328), Expect = 4e-30
Identities = 96/319 (30%), Positives = 150/319 (46%), Gaps = 65/319 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
YTL +K+G+G F Y C++ A+ V + A K I K++L +
Sbjct: 85 YTLSRKLGQGQFGTTYL-------CTDIATGV------DYACKSISKRKLISKED----- 126
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
E V +EI I ++ +NIV+ E Y +I+ EL AGGE+F I+ +
Sbjct: 127 ------VEDVRREIQIMHHLAGHKNIVTIKGAYEDPLYVHIVMELCAGGELFDRIIHRGH 180
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
+SE + + + + V+ H LG++HRD+KPEN L + DD S
Sbjct: 181 YSERKAAELTKIIVGVVEACHSLGVMHRDLKPENFLL------------VNKDDDFS--- 225
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLS-----KQIYQTNTKTPCGTVGYTAPEVVKDERYSM 354
+K DFGLS QI+ K G+ Y APEV+ + Y
Sbjct: 226 ----------------LKAIDFGLSVFFKPGQIF----KDVVGSPYYVAPEVLL-KHYGP 264
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+ D+W G +LY +L G PPF+ E + + + +G F W ISD AK+ +RK+L
Sbjct: 265 EADVWTAGVILYILLSGVPPFWAETQQGIFDAVLKGYIDFDTDPWPVISDSAKDLIRKML 324
Query: 415 EVDPAKRYTSEQLLQDPWL 433
P++R T+ ++L+ PW+
Sbjct: 325 CSSPSERLTAHEVLRHPWI 343
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 130 bits (327), Expect = 5e-30
Identities = 100/348 (28%), Positives = 164/348 (46%), Gaps = 89/348 (25%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
EQ + +Y L++ IG+G F+KV A ++ +EVAIK+I K QL T
Sbjct: 49 EQPHIGNYRLLKTIGKGNFAKVKL-----------ARHILTG--REVAIKIIDKTQLNPT 95
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
+ +++ +E+ I KI++ NIV + E+EK Y+I E +GGE+F
Sbjct: 96 S------------LQKLFREVRIMKILNH-PNIVKLFEVIETEKTLYLIMEYASGGEVFD 142
Query: 233 EIVKYTYFSEDLSRHVIRQ-----------------------LANAVKYMHQLGIVHRDI 269
+V + E +R RQ + +AV+Y HQ IVHRD+
Sbjct: 143 YLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDL 202
Query: 270 KPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-Y 328
K ENLL + +K+ADFG S +
Sbjct: 203 KAENLLLD----------------------------------ADMNIKIADFGFSNEFTV 228
Query: 329 QTNTKTPCGTVGYTAPEVVKDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKI 387
T CG+ Y APE+ + ++Y +VD+W +G +LYT++ G PF + + L E++
Sbjct: 229 GGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERV 288
Query: 388 SRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNS 435
RG+Y P++ +S +N +++ L ++P KR T EQ+++D W+N+
Sbjct: 289 LRGKYRI--PFY--MSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINA 332
>At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 501
Score = 130 bits (327), Expect = 5e-30
Identities = 95/339 (28%), Positives = 154/339 (45%), Gaps = 69/339 (20%)
Query: 103 PQEEPEDVFPEQT-ELKDYTLI-QKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVA 160
P+ V P +T L+D+ L+ +K+G+G F Y +S+ + S+ +
Sbjct: 6 PRRPSNSVLPYETPRLRDHYLLGKKLGQGQFGTTYLCTEKSSSANYACKSIPKR------ 59
Query: 161 IKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYI 220
K++ ++ E V +EI I +S N+V E + +I
Sbjct: 60 -KLVCREDY-----------------EDVWREIQIMHHLSEHPNVVRIKGTYEDSVFVHI 101
Query: 221 IQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPID 280
+ E+ GGE+F IV FSE + +I+ + V+ H LG++HRD+KPEN LF+
Sbjct: 102 VMEVCEGGELFDRIVSKGCFSEREAAKLIKTILGVVEACHSLGVMHRDLKPENFLFDS-- 159
Query: 281 FIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLS------KQIYQTNTKT 334
SDD +K DFGLS + +Y
Sbjct: 160 ----------PSDDAK-------------------LKATDFGLSVFYKPGQYLYDV---- 186
Query: 335 PCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTF 394
G+ Y APEV+K + Y ++D+W G +LY +L G PPF+ E + +I +G+ F
Sbjct: 187 -VGSPYYVAPEVLK-KCYGPEIDVWSAGVILYILLSGVPPFWAETESGIFRQILQGKIDF 244
Query: 395 LRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
W IS+GAK+ + K+L+ P KR ++ + L PW+
Sbjct: 245 KSDPWPTISEGAKDLIYKMLDRSPKKRISAHEALCHPWI 283
>At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 495
Score = 130 bits (326), Expect = 7e-30
Identities = 97/346 (28%), Positives = 157/346 (45%), Gaps = 69/346 (19%)
Query: 103 PQEEPEDVFPEQT-ELKDYTLI-QKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVA 160
P+ V P QT L+D+ L+ +K+G+G F Y +++ + S+ +
Sbjct: 7 PRRPSNTVLPYQTPRLRDHYLLGKKLGQGQFGTTYLCTEKSTSANYACKSIPKR------ 60
Query: 161 IKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYI 220
K++ ++ E V +EI I +S N+V E + +I
Sbjct: 61 -KLVCREDY-----------------EDVWREIQIMHHLSEHPNVVRIKGTYEDSVFVHI 102
Query: 221 IQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPID 280
+ E+ GGE+F IV +FSE + +I+ + V+ H LG++HRD+KPEN LF+
Sbjct: 103 VMEVCEGGELFDRIVSKGHFSEREAVKLIKTILGVVEACHSLGVMHRDLKPENFLFD--- 159
Query: 281 FIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLS------KQIYQTNTKT 334
+PK DD +K DFGLS + +Y
Sbjct: 160 ---SPK------DDAK-------------------LKATDFGLSVFYKPGQYLYDV---- 187
Query: 335 PCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTF 394
G+ Y APEV+K + Y ++D+W G +LY +L G PPF+ E + +I +G+ F
Sbjct: 188 -VGSPYYVAPEVLK-KCYGPEIDVWSAGVILYILLSGVPPFWAETESGIFRQILQGKLDF 245
Query: 395 LRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLP 440
W IS+ AK+ + K+LE P KR ++ + L PW+ P
Sbjct: 246 KSDPWPTISEAAKDLIYKMLERSPKKRISAHEALCHPWIVDEQAAP 291
>At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 567
Score = 129 bits (325), Expect = 9e-30
Identities = 103/350 (29%), Positives = 154/350 (43%), Gaps = 63/350 (18%)
Query: 83 KDGTSQEENTYDESSDATTTPQEEPEDVFP--EQTELKD-YTLIQKIGEGAFSKVYRGIP 139
K ++ N YD+ T P V P Q+++ D Y L +++G G F Y
Sbjct: 22 KPPRGRQRNPYDDPDGLRT---HAPLRVIPMSHQSQISDKYILGRELGRGEFGITYL--- 75
Query: 140 STSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIV 199
C++ + + +A K I K++L E V +E+ I +
Sbjct: 76 ----CTD------RETREALACKSISKRKLRTA-----------VDVEDVRREVTIMSTL 114
Query: 200 SSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYM 259
N+V E + +++ EL GGE+F IV +++E + V R +A V+
Sbjct: 115 PEHPNVVKLKATYEDNENVHLVMELCEGGELFDRIVARGHYTERAAATVARTIAEVVRMC 174
Query: 260 HQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLA 319
H G++HRD+KPEN LF N K +K
Sbjct: 175 HVNGVMHRDLKPENFLFA------NKKEN-------------------------SALKAI 203
Query: 320 DFGLSKQIYQTNTKTPC-GTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDE 378
DFGLS T G+ Y APEV+K Y +VD+W G +LY +LCG PPF+ E
Sbjct: 204 DFGLSVLFKPGERFTEIVGSPYYMAPEVLK-RNYGPEVDVWSAGVILYILLCGVPPFWAE 262
Query: 379 KIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLL 428
+ I RG F R W QIS+ AK+ V+++LE D KR T++Q+L
Sbjct: 263 TEQGVALAILRGVLDFKRDPWSQISESAKSLVKQMLEPDSTKRLTAQQVL 312
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 129 bits (324), Expect = 1e-29
Identities = 94/317 (29%), Positives = 155/317 (48%), Gaps = 66/317 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L++ IG+G F+KV A VI EVAIK+I K L
Sbjct: 122 YKLLKTIGKGNFAKVKL-----------AKHVITGH--EVAIKIIDKTAL---------- 158
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
S+ +++ +E+ I K + NIV E+E+ Y++ E +GGE+F +V +
Sbjct: 159 --NPSSLQKLFREVKIMKQLDH-PNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGR 215
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
E +R RQ+ +AV+Y+H I+HRD+K ENLL L
Sbjct: 216 MKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLL-----------------------L 252
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYS-MQVD 357
D+ + +K+ADFG S N T CG+ Y APE+ ++Y +VD
Sbjct: 253 DQDMN-----------IKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVD 301
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W +G +LYT++ G PF + + L E++ RG+Y P++ +S +N ++K L ++
Sbjct: 302 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI--PFY--MSTDCENLLKKFLVIN 357
Query: 418 PAKRYTSEQLLQDPWLN 434
P +R + + +++D W+N
Sbjct: 358 PQRRSSLDNIMKDRWMN 374
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 129 bits (324), Expect = 1e-29
Identities = 94/317 (29%), Positives = 155/317 (48%), Gaps = 66/317 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L++ IG+G F+KV A VI EVAIK+I K L
Sbjct: 170 YKLLKTIGKGNFAKVKL-----------AKHVITGH--EVAIKIIDKTAL---------- 206
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
S+ +++ +E+ I K + NIV E+E+ Y++ E +GGE+F +V +
Sbjct: 207 --NPSSLQKLFREVKIMKQLDH-PNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGR 263
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
E +R RQ+ +AV+Y+H I+HRD+K ENLL L
Sbjct: 264 MKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLL-----------------------L 300
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYS-MQVD 357
D+ + +K+ADFG S N T CG+ Y APE+ ++Y +VD
Sbjct: 301 DQDMN-----------IKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVD 349
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W +G +LYT++ G PF + + L E++ RG+Y P++ +S +N ++K L ++
Sbjct: 350 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRI--PFY--MSTDCENLLKKFLVIN 405
Query: 418 PAKRYTSEQLLQDPWLN 434
P +R + + +++D W+N
Sbjct: 406 PQRRSSLDNIMKDRWMN 422
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 129 bits (323), Expect = 1e-29
Identities = 99/341 (29%), Positives = 161/341 (47%), Gaps = 67/341 (19%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
L +Y L + +G G+F KV A V+ +VAIK++ ++++ N +
Sbjct: 17 LPNYKLGKTLGIGSFGKV-----------KIAEHVVTGH--KVAIKILNRRKIKNMEME- 62
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
E+V +EI I ++ +I+ + E+ Y++ E + GE+F IV+
Sbjct: 63 ----------EKVRREIKILRLFMH-PHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVE 111
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
ED +R+ +Q+ + V+Y H+ +VHRD+KPENLL +
Sbjct: 112 KGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLD------------------- 152
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPEVVKDERYS-M 354
+K+ADFGLS + + KT CG+ Y APEV+ + Y+
Sbjct: 153 ---------------SRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAGP 197
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+VD+W G +LY +LCG PF DE I L +KI G YT +S A++ + ++L
Sbjct: 198 EVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLP----SHLSSEARDLIPRML 253
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRR 455
VDP KR T ++ Q W ++ LP + P T E+ +
Sbjct: 254 IVDPVKRITIPEIRQHRWFQTH--LPRYLAVSPPDTVEQAK 292
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 129 bits (323), Expect = 1e-29
Identities = 114/399 (28%), Positives = 169/399 (41%), Gaps = 82/399 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + +G G F+KVY G + S G +VAIKVI K D
Sbjct: 15 YNIGRLLGTGNFAKVYHG----TEISTG---------DDVAIKVI----------KKDHV 51
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
+ EQ+ +EIA+ +++ N+V + ++K + + E + GGE+F I +
Sbjct: 52 FKRRGMMEQIEREIAVMRLLRH-PNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGK 110
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
EDL+R +QL +AV + H G+ HRDIKPENLL +
Sbjct: 111 LPEDLARKYFQQLISAVDFCHSRGVFHRDIKPENLLLD---------------------- 148
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-----------TKTPCGTVGYTAPEVVK 348
EG +K+ DFGLS + T CGT Y APEV++
Sbjct: 149 GEG------------DLKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYVAPEVLR 196
Query: 349 DERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAK 407
++ Y D+W G VLY +L GF PF DE + L KI + E F PW+ S +K
Sbjct: 197 NKGYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKIFKAECEF-PPWF---SLESK 252
Query: 408 NCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAYKK 467
+ +LL DP +R + ++ PW + PS S + K +K +
Sbjct: 253 ELLSRLLVPDPEQRISMSEIKMIPWFRK-NFTPSVAFSIDETIPSPPEPPTKKKKKDLNE 311
Query: 468 NASLLYSPAA-------VAMRDAFDVSNAVQRIEDDKRM 499
SP + +M FD+SN + KRM
Sbjct: 312 KEDDGASPRSFNAFQFITSMSSGFDLSNLFEIKRKPKRM 350
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 128 bits (321), Expect = 3e-29
Identities = 98/321 (30%), Positives = 151/321 (46%), Gaps = 69/321 (21%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
LK Y L + IG G F+KV A ++ + VAIK++
Sbjct: 8 LKYYELHETIGTGGFAKVKL-----------ACHILTGEM--VAIKIM------------ 42
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
+KN S ++ EI K + ++I E+ +++ E GGE+F I+
Sbjct: 43 -DKNTLGSDLPRIKTEIEALKNLRH-QHICQLYHVLETANKIFMVLEYCPGGELFDYIIS 100
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
SE+ +R V RQ+ +AV Y+H G HRD+KPENLLF D
Sbjct: 101 QDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLF-----------------DEY 143
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLS---KQIYQTNTKTPCGTVGYTAPEVVKDERY- 352
KL KL DFGL K + +T CG++ Y APE+++ + Y
Sbjct: 144 HKL-----------------KLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYL 186
Query: 353 SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRK 412
+ D+W +G +LY ++CGF PF D+ + L +KI RG+Y P W +S + +++
Sbjct: 187 GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDV--PKW--LSPSSILLLQQ 242
Query: 413 LLEVDPAKRYTSEQLLQDPWL 433
+L+VDP KR + + LL PW+
Sbjct: 243 MLQVDPKKRISMKNLLNHPWI 263
>At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 484
Score = 127 bits (320), Expect = 3e-29
Identities = 94/319 (29%), Positives = 147/319 (45%), Gaps = 65/319 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y+L K+G+G F Y S G +E A K I K++L +
Sbjct: 24 YSLGHKLGQGQFGTTYM----CKEISTG---------REYACKSITKRKLISKED----- 65
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
E V +EI I ++ +NIV+ E Y +I+ EL +GGE+F I++ +
Sbjct: 66 ------VEDVRREIQIMHHLAGYKNIVTIKGAYEDPLYVHIVMELCSGGELFDRIIQRGH 119
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
+SE + +I+ + V+ H LG++HRD+KPEN L + DD S
Sbjct: 120 YSERKAAELIKIIVGVVEACHSLGVMHRDLKPENFLL------------VNKDDDFS--- 164
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLS-----KQIYQTNTKTPCGTVGYTAPEVVKDERYSM 354
+K DFGLS QI++ +P Y APEV+ + Y
Sbjct: 165 ----------------LKAIDFGLSVFFKPGQIFEDVVGSPY----YVAPEVLL-KHYGP 203
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+ D+W G +LY ++ G PPF+ E + + + +G F W ISD AKN +R +L
Sbjct: 204 EADVWTAGVILYILVSGVPPFWAETQQGIFDAVLKGHIDFDSDPWPLISDSAKNLIRGML 263
Query: 415 EVDPAKRYTSEQLLQDPWL 433
P++R T+ Q+L+ PW+
Sbjct: 264 CSRPSERLTAHQVLRHPWI 282
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 127 bits (319), Expect = 4e-29
Identities = 97/347 (27%), Positives = 163/347 (46%), Gaps = 66/347 (19%)
Query: 114 QTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTN 173
++E Y +I+ +G G F+ V + S K AIK+I K+++ T+
Sbjct: 161 KSENSHYEIIRTLGSGTFAVVKLAVEVNSG-------------KWYAIKIINKRKILLTS 207
Query: 174 KKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGE 233
+ K +T E +EI I K + +V + E++ +I+ E + GG++
Sbjct: 208 SE------KRAT-EMFQREIDILKSLHH-PGVVQCHEIFENDDELFIVMEYVEGGDLMDF 259
Query: 234 IVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSD 293
++ E + +++QL + ++H+ G+ HRDIKPEN+L DF
Sbjct: 260 LIANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITN-DFH----------- 307
Query: 294 DPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT--KTPCGTVGYTAPEVVK--- 348
+K++DFGL+K I+ T T +T CGT+GY APEV+K
Sbjct: 308 ----------------------LKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKN 345
Query: 349 ---DERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDG 405
D Y +VD+W +GCVLY +L PF E IS+G Y ++IS+
Sbjct: 346 VNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEE 405
Query: 406 AKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGE 452
+ + ++LE++P KR + + LQ PW + + + +H PS+ E
Sbjct: 406 GIDLINRMLEINPEKRISESEALQHPW---FYTVSTHEHRTPPSSSE 449
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 127 bits (318), Expect = 6e-29
Identities = 86/291 (29%), Positives = 135/291 (45%), Gaps = 59/291 (20%)
Query: 154 QQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQE 213
Q +E A+K++ ++ NT + E+A ++ S N+V+ +
Sbjct: 432 QSGQEFAVKILSRRLEANTQR-----------------EVAALRLCQSHPNVVNLHEVHH 474
Query: 214 SEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQ-LGIVHRDIKPE 272
+ + Y++ ELL GGE+ I K +FSE + ++R L +AV +MH+ G+VHRD+KPE
Sbjct: 475 DQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPE 534
Query: 273 NLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN- 331
N+L+ + D P VK+ DFG ++ Q+
Sbjct: 535 NILY--------------ADDTPGAP-----------------VKIIDFGFARLRPQSPG 563
Query: 332 --TKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPF-------FDEKIDV 382
+TPC T+ Y APE++ + Y D+W +G +LY +L G PF +
Sbjct: 564 VPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAE 623
Query: 383 LTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
+ KI G ++ W +S+ AK VR LL VDPAKR E L WL
Sbjct: 624 IMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWL 674
Score = 89.7 bits (221), Expect = 1e-17
Identities = 77/313 (24%), Positives = 144/313 (45%), Gaps = 58/313 (18%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
E+ ++++ L++ +G GA+ KV+ + + + K A+KV+ K L
Sbjct: 26 EKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAG----------KLYAMKVLRKAALVQR 75
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
K T E E ++ ++V +V+ +++ ++I + ++GGE+F
Sbjct: 76 AK----------TQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFT 125
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+ + YF E R ++ A++++H+LGI++RD+K EN+L +
Sbjct: 126 HLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLD--------------- 170
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIY---QTNTKTPCGTVGYTAPEVVKD 349
EG + L DFGLSK+ + T + CGT+ Y APE+++
Sbjct: 171 -------SEGH------------IVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRS 211
Query: 350 ER-YSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKN 408
+ + VD W +G +L+ +L G PF E ++SR P+ +I A++
Sbjct: 212 KTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQD 271
Query: 409 CVRKLLEVDPAKR 421
+++LL DP KR
Sbjct: 272 LLQRLLCKDPKKR 284
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 127 bits (318), Expect = 6e-29
Identities = 98/343 (28%), Positives = 164/343 (47%), Gaps = 76/343 (22%)
Query: 94 DESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIA 153
++SS ATT P + L Y L +++G G+F+KV+ A S+ +
Sbjct: 9 NQSSPATT----------PAKILLGKYELGRRLGSGSFAKVHL-----------ARSIES 47
Query: 154 QQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQE 213
+ VA+K+I K++ T + G E ++++EI + + NI+ +
Sbjct: 48 DEL--VAVKIIEKKK---TIESGMEP--------RIIREIDAMRRLRHHPNILKIHEVMA 94
Query: 214 SEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPEN 273
++ Y++ EL +GGE+F ++++ E +R +QLA+A+++ HQ G+ HRD+KP+N
Sbjct: 95 TKSKIYLVMELASGGELFSKVLRRGRLPESTARRYFQQLASALRFSHQDGVAHRDVKPQN 154
Query: 274 LLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLS---KQIYQT 330
LL LDE +K++DFGLS + +
Sbjct: 155 LL-----------------------LDE-----------QGNLKVSDFGLSALPEHLQNG 180
Query: 331 NTKTPCGTVGYTAPEVVKDERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISR 389
T CGT YTAPEV+ Y + D W G +L+ +L G PF D I + KI R
Sbjct: 181 LLHTACGTPAYTAPEVISRRGYDGAKADAWSCGVILFVLLVGDVPFDDSNIAAMYRKIHR 240
Query: 390 GEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
+Y F P W IS AK+ + ++L+ +P R + E +++ W
Sbjct: 241 RDYRF--PSW--ISKQAKSIIYQMLDPNPVTRMSIETVMKTNW 279
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 127 bits (318), Expect = 6e-29
Identities = 95/317 (29%), Positives = 154/317 (47%), Gaps = 66/317 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y +I+ +G+G F+KV I + +EVAIK+I K L
Sbjct: 63 YKIIKTLGKGNFAKVKLAIHLPTG-------------REVAIKLIDKTAL---------- 99
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
T +++ +E+ I K ++ NIV + ESE+ Y++ E ++GGE+F +VK
Sbjct: 100 --NTIARQKLYREVNIMKKLNH-PNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGR 156
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
E +R + RQL +A++Y H IVHRD+K ENLL D KL
Sbjct: 157 MRERDARVLFRQLVSAIEYCHSKSIVHRDLKAENLLL-----------------DQQMKL 199
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIY-QTNTKTPCGTVGYTAPEVVKDERYS-MQVD 357
K+ADFG S + +T CG+ Y APE+ + ++YS +VD
Sbjct: 200 -----------------KIADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKYSGPEVD 242
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
W +G VLYT++ G PF + L +++ RG+Y P++ +S ++ +RK L ++
Sbjct: 243 SWSLGVVLYTLVSGSLPFDGTNLKELRDRVLRGKYRV--PYY--VSIECESLIRKFLVLN 298
Query: 418 PAKRYTSEQLLQDPWLN 434
P +R + ++ D W+N
Sbjct: 299 PTQRTSLSAVMADRWIN 315
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 126 bits (317), Expect = 7e-29
Identities = 94/361 (26%), Positives = 155/361 (42%), Gaps = 73/361 (20%)
Query: 91 NTYDESSDATTTPQEEPEDVFPE----------QTELKDYTLIQKIGEGAFSKVYRGIPS 140
NT + P+ PE+ Q L+D+ + + +G+G F VY
Sbjct: 94 NTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREK 153
Query: 141 TSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVS 200
S +A+KV+ K QL K Q+ +E+ I +
Sbjct: 154 QSKFI-------------LALKVLFKAQLE-----------KAGVEHQLRREVEIQSHLR 189
Query: 201 SGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMH 260
NI+ + Y+I E G ++ E+ K + F E + I +LANA+ Y H
Sbjct: 190 H-PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCH 248
Query: 261 QLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLAD 320
++HRDIKPENLL L S+ + +K+AD
Sbjct: 249 SKRVIHRDIKPENLL-------------LGSAGE---------------------LKIAD 274
Query: 321 FGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKI 380
FG S + T CGT+ Y PE+++ + +VD+W +G + Y L G PPF
Sbjct: 275 FGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTY 334
Query: 381 DVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLP 440
++ISR E+TF D +++GA++ + +LL+ +P++R ++L+ PW+ + P
Sbjct: 335 QETYKRISRVEFTFP----DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 390
Query: 441 S 441
S
Sbjct: 391 S 391
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 126 bits (317), Expect = 7e-29
Identities = 98/308 (31%), Positives = 140/308 (44%), Gaps = 46/308 (14%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV--KYTYFSEDL 244
E V +E+ I + ++ EN+V F + E + YI+ EL GGE+ I+ K + +SE
Sbjct: 151 EDVKREVKILQALTGHENVVRFYNAFEDKNSVYIVMELCEGGELLDRILARKDSRYSERD 210
Query: 245 SRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVF 304
+ V+RQ+ H G+VHRD+KPEN LF K D P
Sbjct: 211 AAVVVRQMLKVAAECHLRGLVHRDMKPENFLF-----------KSTEEDSP--------- 250
Query: 305 RPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVDMWGVGC 363
+K DFGLS I G+ Y APEV+K R + D+W +G
Sbjct: 251 -----------LKATDFGLSDFIKPGKKFHDIVGSAYYVAPEVLK-RRSGPESDVWSIGV 298
Query: 364 VLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYT 423
+ Y +LCG PF+D+ D + +++ + + F R W IS+ AK+ V+KLL DP R T
Sbjct: 299 ISYILLCGRRPFWDKTEDGIFKEVLKNKPDFRRKPWPTISNSAKDFVKKLLVKDPRARLT 358
Query: 424 SEQLLQDPWLNSYDCLPSADHSNAP---STGEKRRHSHKHSRK---AYKKNASLLYSPAA 477
+ Q L PW+ D S P S R K SR A + A+ L
Sbjct: 359 AAQALSHPWVRE-----GGDASEIPIDISVLNNMRQFVKFSRLKQFALRALATTLDEEEL 413
Query: 478 VAMRDAFD 485
+RD FD
Sbjct: 414 ADLRDQFD 421
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 125 bits (315), Expect = 1e-28
Identities = 100/320 (31%), Positives = 154/320 (47%), Gaps = 72/320 (22%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYK---EVAIKVIIKQQLPNTNKKG 176
Y + + +GEG+F KV +A YK +VA+K I +Q L
Sbjct: 34 YIIRETLGEGSFGKVK----------------LATHYKTQQKVALKFISRQLLK------ 71
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
K+ +V +EI+ K++ +I+ D + ++ E AGGE+F IV+
Sbjct: 72 -----KSDMHMRVEREISYLKLLRH-PHIIKLYDVITTPTDIVMVIEY-AGGELFDYIVE 124
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
+ED R +Q+ A++Y H+ IVHRD+KPENLL
Sbjct: 125 KKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLL--------------------- 163
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPEVVKDERYS-M 354
LD+ + VK+ADFGLS + N KT CG+ Y APEV+ + Y+
Sbjct: 164 --LDDNLN-----------VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAGP 210
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+VD+W G VLY +L G PF DE I L +K++ Y D +S GA++ +R+++
Sbjct: 211 EVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMP----DFLSPGAQSLIRRMI 266
Query: 415 EVDPAKRYTSEQLLQDPWLN 434
DP +R T +++ +DPW N
Sbjct: 267 VADPMQRITIQEIRRDPWFN 286
>At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 125 bits (315), Expect = 1e-28
Identities = 86/250 (34%), Positives = 121/250 (48%), Gaps = 35/250 (14%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV--KYTYFSEDL 244
E V +E+ I +S EN+V F + E + Y YI+ EL GGE+ I+ K +SE
Sbjct: 105 EDVKREVQILIALSGHENVVQFHNAFEDDDYVYIVMELCEGGELLDRILSKKGNRYSEKD 164
Query: 245 SRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVF 304
+ V+RQ+ H G+VHRD+KPEN LF+ S +LD +
Sbjct: 165 AAVVVRQMLKVAGECHLHGLVHRDMKPENFLFK------------------SAQLDSPL- 205
Query: 305 RPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVDMWGVGC 363
K DFGLS I G+ Y APEV+K R + D+W +G
Sbjct: 206 ------------KATDFGLSDFIKPGKRFHDIVGSAYYVAPEVLK-RRSGPESDVWSIGV 252
Query: 364 VLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYT 423
+ Y +LCG PF+D D + +++ R + F R W ISD AK+ V+KLL DP R T
Sbjct: 253 ITYILLCGRRPFWDRTEDGIFKEVLRNKPDFSRKPWATISDSAKDFVKKLLVKDPRARLT 312
Query: 424 SEQLLQDPWL 433
+ Q L W+
Sbjct: 313 AAQALSHAWV 322
>At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 536
Score = 125 bits (315), Expect = 1e-28
Identities = 96/315 (30%), Positives = 147/315 (46%), Gaps = 58/315 (18%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
YT+ + +G G F Y +T N +NG VA+K I K ++ +
Sbjct: 71 YTIGKLLGHGQFGFTY---VATDN-NNG---------NRVAVKRIDKAKMTQPIE----- 112
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
E V +E+ I + + EN+V F + E + Y YI+ EL GGE+ I+ Y
Sbjct: 113 ------VEDVKREVKILQALGGHENVVGFHNAFEDKTYIYIVMELCDGGELLDRILANRY 166
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
+D + V+RQ+ H G+VHRD+KPEN LF +S+++ S+
Sbjct: 167 TEKDAAV-VVRQMLKVAAECHLRGLVHRDMKPENFLF-------------KSTEEGSS-- 210
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQ-TNTKTPCGTVGYTAPEVVKDERYSMQVDM 358
+K DFGLS I + G+ Y APEV+K R + D+
Sbjct: 211 ----------------LKATDFGLSDFIKPGVKFQDIVGSAYYVAPEVLK-RRSGPESDV 253
Query: 359 WGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDP 418
W +G + Y +LCG PF+D+ D + ++ R + F W IS+GAK+ V+KLL +P
Sbjct: 254 WSIGVITYILLCGRRPFWDKTQDGIFNEVMRKKPDFREVPWPTISNGAKDFVKKLLVKEP 313
Query: 419 AKRYTSEQLLQDPWL 433
R T+ Q L W+
Sbjct: 314 RARLTAAQALSHSWV 328
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 125 bits (315), Expect = 1e-28
Identities = 103/338 (30%), Positives = 156/338 (45%), Gaps = 72/338 (21%)
Query: 100 TTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEV 159
T+ P+E P+ L Y + + +G G F+KVY +N + V
Sbjct: 9 TSLPKERSS---PQALILGRYEMGKLLGHGTFAKVYLARNVKTN-------------ESV 52
Query: 160 AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYY 219
AIKVI K EK K + +EI+I + V NIV + ++ Y
Sbjct: 53 AIKVIDK-----------EKVLKGGLIAHIKREISILRRVRH-PNIVQLFEVMATKAKIY 100
Query: 220 IIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPI 279
+ E + GGE+F ++ K E+++R +QL +AV + H G+ HRD+KPENLL
Sbjct: 101 FVMEYVRGGELFNKVAKGR-LKEEVARKYFQQLISAVTFCHARGVYHRDLKPENLL---- 155
Query: 280 DFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSK---QIYQTNT-KTP 335
LDE +K++DFGLS QI Q T
Sbjct: 156 -------------------LDEN-----------GNLKVSDFGLSAVSDQIRQDGLFHTF 185
Query: 336 CGTVGYTAPEVVKDERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTF 394
CGT Y APEV+ + Y + +VD+W G +L+ ++ G+ PF D + + +KI RGE F
Sbjct: 186 CGTPAYVAPEVLARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGE--F 243
Query: 395 LRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
P W S + KLLE +P KR+T +++++ W
Sbjct: 244 RCPRW--FSTELTRLLSKLLETNPEKRFTFPEIMENSW 279
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 125 bits (314), Expect = 2e-28
Identities = 94/321 (29%), Positives = 151/321 (46%), Gaps = 71/321 (22%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + ++G G F KV +N ++VAIK+I K+QL + +
Sbjct: 11 YAVHDELGSGGFGKVRLATHLLTN-------------QKVAIKIIDKKQLGHDLPR---- 53
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
T L+ + S +NI + E+E ++I+ E +GGE+F IV+
Sbjct: 54 ---VQTEMDALRNL-------SHQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKER 103
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
E +RH RQL +A+ ++H G HRD+KPENLL L
Sbjct: 104 LEESEARHFFRQLVSAIAFVHSQGYAHRDLKPENLL-----------------------L 140
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQ-----IYQTNTKTPCGTVGYTAPEVVKDERYS- 353
E + +KL DFGL + I + N T CG+ Y APE+++ +Y
Sbjct: 141 TEDLH-----------LKLIDFGLCAKTEKGRIDKHNLDTCCGSPAYAAPELIQGLQYKG 189
Query: 354 MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKL 413
+ D+W +G +LYT+L G PF D+ + ++ +KI G F P + +S +K +R +
Sbjct: 190 NEADVWSMGILLYTLLVGALPFEDDNMQIMYKKIQSG--CFYEP--EFLSPLSKQLLRAM 245
Query: 414 LEVDPAKRYTSEQLLQDPWLN 434
L+V P +R + ++LL+ WLN
Sbjct: 246 LQVVPERRISVKKLLEHDWLN 266
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 601
Score = 125 bits (314), Expect = 2e-28
Identities = 89/278 (32%), Positives = 129/278 (46%), Gaps = 53/278 (19%)
Query: 174 KKGDEKN----------GKTSTA---EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYI 220
KKGD K K +TA E V +E+ I + +S N+ F D E YI
Sbjct: 168 KKGDNKGQQVAVKVIPKAKMTTAIAIEDVRREVKILRALSGHNNLPHFYDAYEDHDNVYI 227
Query: 221 IQELLAGGEIFGEIV----KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLF 276
+ EL GGE+ I+ KYT E+ ++ V+ Q+ N V + H G+VHRD+KPEN LF
Sbjct: 228 VMELCEGGELLDRILSRGGKYT---EEDAKTVMIQILNVVAFCHLQGVVHRDLKPENFLF 284
Query: 277 EPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPC 336
S +D S +K DFGLS +
Sbjct: 285 T-------------SKEDTSQ------------------LKAIDFGLSDYVRPDERLNDI 313
Query: 337 -GTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFL 395
G+ Y APEV+ YS + D+W VG ++Y +LCG PF+ + + + + +F
Sbjct: 314 VGSAYYVAPEVLH-RSYSTEADIWSVGVIVYILLCGSRPFWARTESGIFRAVLKADPSFD 372
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
P W +S A++ V++LL DP KR T+ Q L PW+
Sbjct: 373 DPPWPLLSSEARDFVKRLLNKDPRKRLTAAQALSHPWI 410
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 125 bits (314), Expect = 2e-28
Identities = 85/278 (30%), Positives = 137/278 (48%), Gaps = 53/278 (19%)
Query: 158 EVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKY 217
EVAIK+I K QL TN ++V +E+ I K + +I+ E++
Sbjct: 166 EVAIKIIDKSQLDQTN------------LQKVYREVEIMKRLKH-PHIIKLYQVMETKNM 212
Query: 218 YYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFE 277
YI+ E + GEIF I KY SE +R Q+ +AV+Y H+ GIVHRD+K ENLL
Sbjct: 213 IYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKAENLL-- 270
Query: 278 PIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPC 336
+D N +K+ADFG S T C
Sbjct: 271 -LDLNMN-------------------------------IKIADFGFSNHFKPGELLATWC 298
Query: 337 GTVGYTAPEVVKDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFL 395
G+ Y APEV + ++Y+ ++D+W +G VLY ++CG PF + L +++ G +
Sbjct: 299 GSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRI- 357
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
P++ +S ++ +R++L ++P +RYT +Q+ + W+
Sbjct: 358 -PFF--MSSECEHLIRRMLVLEPTRRYTIDQIKRHRWM 392
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 125 bits (313), Expect = 2e-28
Identities = 107/415 (25%), Positives = 181/415 (42%), Gaps = 72/415 (17%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + +G+G F+KVY + G S VAIKVI K+++
Sbjct: 12 YEVGKFLGQGTFAKVYHA----RHLKTGDS---------VAIKVIDKERIL--------- 49
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
K EQ+ +EI+ +++ NIV + ++ Y + E + GGE+F + V
Sbjct: 50 --KVGMTEQIKREISAMRLLRH-PNIVELHEVMATKSKIYFVMEHVKGGELFNK-VSTGK 105
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
ED++R +QL AV + H G+ HRD+KPENLL L
Sbjct: 106 LREDVARKYFQQLVRAVDFCHSRGVCHRDLKPENLL-----------------------L 142
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLS----KQIYQTNTKTPCGTVGYTAPEVVKDERYS-M 354
DE +K++DFGLS + T CGT Y APEV+ Y
Sbjct: 143 DE-----------HGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDGF 191
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+ D+W G +L+ +L G+ PF D + L +KI + E F P W ++ GAK ++++L
Sbjct: 192 KADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKF--PNW--LAPGAKRLLKRIL 247
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAYKKNASLLYS 474
+ +P R ++E++++ W S T S + KK L +
Sbjct: 248 DPNPNTRVSTEKIMKSSWFRK-GLQEEVKESVEEETEVDAEAEGNASAEKEKKRCINLNA 306
Query: 475 PAAVAMRDAFDVSNAVQRIE--DDKRMTPGPKXXXXXXXLGVLAEDAEAEIQYRE 527
+++ FD+S ++ E ++ R T + L + +D + +++ +E
Sbjct: 307 FEIISLSTGFDLSGLFEKGEEKEEMRFTSNREASEITEKLVEIGKDLKMKVRKKE 361
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 125 bits (313), Expect = 2e-28
Identities = 80/289 (27%), Positives = 138/289 (47%), Gaps = 45/289 (15%)
Query: 172 TNKKGDEKNGKT--STAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGE 229
+ K G E KT E V +E+ I + +S +V+ E ++++ EL +GG
Sbjct: 126 SRKNGTEFACKTLKKGEETVHREVEIMQHLSGHPRVVTLHAVYEESDCFHLVMELCSGGR 185
Query: 230 IFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKL 289
+ ++VK +SE + ++ + L + Y H++G+VHRDIKPEN+L
Sbjct: 186 LIDQMVKVGRYSEQRAANIFKDLMLVINYCHEMGVVHRDIKPENILL------------- 232
Query: 290 RSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP-CGTVGYTAPEVVK 348
++LADFGL+ +I + T + G+ Y APEV+
Sbjct: 233 ---------------------TAAGKIQLADFGLAMRIAKGQTLSGLAGSPAYVAPEVLS 271
Query: 349 DERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKN 408
E YS +VD+W G +LY +L G PF + +D + E I + F W+ +S A++
Sbjct: 272 -ENYSEKVDVWSAGVLLYALLSGVLPFKGDSLDAIFEAIKNVKLDFNTGVWESVSKPARD 330
Query: 409 CVRKLLEVDPAKRYTSEQLLQDPWLNSYD-------CLPSADHSNAPST 450
+ ++L + + R T++++L+ PW+ Y C+ S S A S+
Sbjct: 331 LLARMLTREESARITADEVLRHPWILFYTDRTLKTMCIKSKHKSQAGSS 379
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 125 bits (313), Expect = 2e-28
Identities = 79/245 (32%), Positives = 124/245 (50%), Gaps = 37/245 (15%)
Query: 192 EIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQ 251
EIAI ++ N+V+ E + +++ EL AGGE+F ++ KY +SE +R + +
Sbjct: 92 EIAIMAKLAGHPNVVNLKAVYEEKDSVHLVMELCAGGELFHKLEKYGRYSEVRARVLFKH 151
Query: 252 LANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXX 311
L VK+ H GIVHRD+KPEN+L + SS P
Sbjct: 152 LMQVVKFCHDSGIVHRDLKPENILMATM-----------SSSSP---------------- 184
Query: 312 XXXVVKLADFGLSKQIYQTNTKTPCGTVG---YTAPEVVKDERYSMQVDMWGVGCVLYTV 368
+KLADFGL+ I + GTVG Y APEV+ Y+ D+W G +LY +
Sbjct: 185 ----IKLADFGLATYIKPGEKLS--GTVGSPFYIAPEVLAGG-YNQAADVWSAGVILYIL 237
Query: 369 LCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLL 428
L G PPF+ + + + + + F WD I+ AK+ +R +L VDP++R +++++L
Sbjct: 238 LSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDNITSYAKDLIRGMLCVDPSQRLSADEVL 297
Query: 429 QDPWL 433
W+
Sbjct: 298 AHSWM 302
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 124 bits (312), Expect = 3e-28
Identities = 94/318 (29%), Positives = 155/318 (48%), Gaps = 66/318 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + +G+G V G+ +C G K+VAIK+I +++L
Sbjct: 18 YRLEKTLGKGQTGLVKLGV----HCVIG---------KKVAIKIINREKLSE-------- 56
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
S +V +EIAI K++ +++ D E++KY Y+I E ++GGE+F +VK
Sbjct: 57 ----SVLMKVEREIAIMKLIDH-PHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGR 111
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
+ +R RQ+ +A+ + H I HRD+KPENLL L
Sbjct: 112 LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLL-----------------------L 148
Query: 300 DEGVFRPXXXXXXXXVVKLADFGL-SKQIYQTNTKTPCGTVGYTAPEVVKDERYS-MQVD 357
DE +K+ADFG+ S Q + +T CG+ Y PEV++ E+Y + D
Sbjct: 149 DE-----------KNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKAD 197
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +LY +L G PF D+ + L EK+ RG F P + + ++ +R ++EV+
Sbjct: 198 VWSCGVILYALLVGALPFDDDNLRQLLEKVKRG--VFHIPHF--VPPDCQSLLRGMIEVN 253
Query: 418 PAKRYTSEQLLQDPWLNS 435
P +R T ++ + PW+ +
Sbjct: 254 PDRRLTLAEINRHPWVTA 271
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 124 bits (310), Expect = 5e-28
Identities = 87/329 (26%), Positives = 148/329 (44%), Gaps = 63/329 (19%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
E L+D+ + + +G+G F VY S +A+KV+ K QL
Sbjct: 125 EAVALEDFEIGRPLGKGKFGNVYLAREKQSKFI-------------LALKVLFKAQLE-- 169
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
K Q+ +E+ I + NI+ + Y+I E G ++
Sbjct: 170 ---------KAGVEHQLRREVEIQSHLRH-PNILRLYGYFHDATRVYLILEYAPLGTVYR 219
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
E+ K + F E + ++ ++ANA+ Y H ++HRDIKPENLL L S+
Sbjct: 220 ELQKLSKFDEQRTANLYNRIANALSYCHSKRVIHRDIKPENLL-------------LGSA 266
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERY 352
+ +K+ADFG S + T CGT+ Y PE+++ +
Sbjct: 267 GE---------------------LKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMH 305
Query: 353 SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRK 412
+VD+W +G + Y L G PPF ++ISR E+TF D +++GA++ + +
Sbjct: 306 DEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFP----DFVTEGARDLISR 361
Query: 413 LLEVDPAKRYTSEQLLQDPWLNSYDCLPS 441
LL+ +P++R ++L+ PW+ + PS
Sbjct: 362 LLKHNPSQRPMLREVLEHPWITANSSKPS 390
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 124 bits (310), Expect = 5e-28
Identities = 95/346 (27%), Positives = 149/346 (42%), Gaps = 56/346 (16%)
Query: 90 ENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGAS 149
E+ D D+ + + F + E K Y L +++G G F N
Sbjct: 114 EDVVDHGGDSGGGERLDKNFGFGKNFEGK-YELGKEVGRGHFGHTCWAKAKKGKMKN--- 169
Query: 150 SVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFI 209
+ VA+K+I K ++ +T + E V +E+ + K +S ++V F
Sbjct: 170 -------QTVAVKIISKAKMTST-----------LSIEDVRREVKLLKALSGHRHMVKFY 211
Query: 210 DFQESEKYYYIIQELLAGGEIFGEIV-KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRD 268
D E +++ EL GGE+ I+ + + E ++ ++ Q+ +A + H G+VHRD
Sbjct: 212 DVYEDADNVFVVMELCEGGELLDRILARGGRYPEVDAKRILVQILSATAFFHLQGVVHRD 271
Query: 269 IKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI- 327
+KPEN LF R+ D ++K+ DFGLS I
Sbjct: 272 LKPENFLFTS-----------RNED--------------------AILKVIDFGLSDFIR 300
Query: 328 YQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKI 387
Y G+ Y APEV+ YS + DMW +G + Y +LCG PF+ + +
Sbjct: 301 YDQRLNDVVGSAYYVAPEVLH-RSYSTEADMWSIGVISYILLCGSRPFYGRTESAIFRCV 359
Query: 388 SRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
R F W IS AK+ V++LL D KR T+ Q L PWL
Sbjct: 360 LRANPNFEDMPWPSISPTAKDFVKRLLNKDHRKRMTAAQALAHPWL 405
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 123 bits (309), Expect = 6e-28
Identities = 96/331 (29%), Positives = 148/331 (44%), Gaps = 67/331 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + IGEG F+KV N G S VA+K++ + +
Sbjct: 9 YELGRTIGEGTFAKV----KFAQNTETGES---------VAMKIVDRSTII--------- 46
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
K +Q+ +EI+I K+V +V + S YII E + GGE+F +IV+
Sbjct: 47 --KRKMVDQIKREISIMKLVRH-PCVVRLYEVLASRTKIYIILEYITGGELFDKIVRNGR 103
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
SE +R QL + V Y H G+ HRD+KPENLL +
Sbjct: 104 LSESEARKYFHQLIDGVDYCHSKGVYHRDLKPENLLLD---------------------- 141
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQ--TNTKTPCGTVGYTAPEVVKDERYSMQV- 356
+K++DFGLS Q T KT CGT Y APEV+ + Y+ V
Sbjct: 142 ------------SQGNLKISDFGLSALPEQGVTILKTTCGTPNYVAPEVLSHKGYNGAVA 189
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D+W G +LY ++ G+ PF + + L KI + E++ + GAK+ + ++L+
Sbjct: 190 DIWSCGVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSCP----SYFALGAKSLINRILDP 245
Query: 417 DPAKRYTSEQLLQDPW-LNSYDCLPSADHSN 446
+P R T ++ +D W L Y + D+ +
Sbjct: 246 NPETRITIAEIRKDEWFLKDYTPVQLIDYEH 276
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 123 bits (308), Expect = 8e-28
Identities = 85/279 (30%), Positives = 131/279 (46%), Gaps = 45/279 (16%)
Query: 157 KEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEK 216
+EVA+KVI K ++ E V +E+ + + ++ +N+V F D E ++
Sbjct: 150 QEVAVKVIPKSKMTTA-----------IAIEDVSREVKMLRALTGHKNLVQFYDAFEDDE 198
Query: 217 YYYIIQELLAGGEIFGEIVKYT-YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLL 275
YI+ EL GGE+ +I++ +SED ++ V+ Q+ + V Y H G+VHRD+KPEN L
Sbjct: 199 NVYIVMELCKGGELLDKILQRGGKYSEDDAKKVMVQILSVVAYCHLQGVVHRDLKPENFL 258
Query: 276 FEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP 335
F S+ D ++ L K DFGLS +
Sbjct: 259 F--------------STKDETSPL-----------------KAIDFGLSDYVKPDERLND 287
Query: 336 C-GTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTF 394
G+ Y APEV+ Y + DMW +G + Y +LCG PF+ + + + E F
Sbjct: 288 IVGSAYYVAPEVLH-RTYGTEADMWSIGVIAYILLCGSRPFWARTESGIFRAVLKAEPNF 346
Query: 395 LRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
W +S A + V++LL D KR T+ Q L PWL
Sbjct: 347 EEAPWPSLSPEAVDFVKRLLNKDYRKRLTAAQALCHPWL 385
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 123 bits (308), Expect = 8e-28
Identities = 81/300 (27%), Positives = 141/300 (47%), Gaps = 34/300 (11%)
Query: 174 KKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGE 233
K+ + + + + E + +E++I K + N+++ + E++ +I EL+AGGE+F
Sbjct: 46 KRRTKSSRRGVSREDIEREVSILKEIQH-PNVITLHEVYENKTDVILILELVAGGELFDF 104
Query: 234 IVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSD 293
+ + +E+ + ++Q+ N V Y+H L I H D+KPEN++
Sbjct: 105 LAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML----------------- 147
Query: 294 DPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-YQTNTKTPCGTVGYTAPEVVKDERY 352
LD V +P +K+ DFGL+ +I + K GT + APE+V E
Sbjct: 148 -----LDRNVPKPR--------IKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPL 194
Query: 353 SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRK 412
++ DMW +G + Y +L G PF + +S Y F ++ S AK+ +R+
Sbjct: 195 GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRR 254
Query: 413 LLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAYKKNASLL 472
LL DP KR T + LQ PW+ D + S S + +RK +K++ L+
Sbjct: 255 LLVKDPKKRMTIQDSLQHPWIKPKDTQQAL--SRKASAVNMEKFKKFAARKKWKQSVRLI 312
>Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 360
Score = 122 bits (307), Expect = 1e-27
Identities = 98/342 (28%), Positives = 157/342 (45%), Gaps = 63/342 (18%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + IG+G FS V R C N + ++ A+K++ + ++ E
Sbjct: 12 YELCEVIGKGPFSVVRR-------CINRETG------QQFAVKIVDVAKFTSSPGLSTED 58
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT- 238
+ ++ +LK +IV ++ S+ Y++ E + G ++ EIVK
Sbjct: 59 LKREASICHMLKH----------PHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRAD 108
Query: 239 ---YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDP 295
+SE ++ H +RQ+ A++Y H I+HRD+KP +L L S ++
Sbjct: 109 AGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVL-------------LASKENS 155
Query: 296 STKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP--CGTVGYTAPEVVKDERYS 353
+ VKL FG++ Q+ ++ GT + APEVVK E Y
Sbjct: 156 AP------------------VKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYG 197
Query: 354 MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKL 413
VD+WG G +L+ +L G PF+ K + L E I +G+Y W IS+ AK+ VR++
Sbjct: 198 KPVDVWGCGVILFILLSGCLPFYGTK-ERLFEGIIKGKYKMNPRQWSHISESAKDLVRRM 256
Query: 414 LEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRR 455
L +DPA+R T + L PWL D H P T E+ R
Sbjct: 257 LMLDPAERITVYEALNHPWLKERDRYAYKIH--LPETVEQLR 296
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 122 bits (306), Expect = 1e-27
Identities = 94/321 (29%), Positives = 151/321 (46%), Gaps = 69/321 (21%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
++ Y L + +G+G F+KVY N G S VAIKVI KQ++
Sbjct: 9 MRKYELGRLLGQGTFAKVYHA----RNIKTGES---------VAIKVIDKQKV------- 48
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
K +Q+ +EI++ ++V ++V + S+ Y E + GGE+F ++ K
Sbjct: 49 ----AKVGLIDQIKREISVMRLVRH-PHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSK 103
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
E+++R +QL A+ Y H G+ HRD+KPENLL
Sbjct: 104 GK-LKENIARKYFQQLIGAIDYCHSRGVYHRDLKPENLL--------------------- 141
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLS--KQIYQTN--TKTPCGTVGYTAPEVVKDERY 352
LDE +K++DFGLS ++ Q + T CGT Y APEV+ + Y
Sbjct: 142 --LDEN-----------GDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGY 188
Query: 353 -SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVR 411
+ D+W G VLY +L GF PF ++ + + KI++GE F P W K +
Sbjct: 189 DGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGE--FKCPNW--FPPEVKKLLS 244
Query: 412 KLLEVDPAKRYTSEQLLQDPW 432
++L+ +P R E+++++ W
Sbjct: 245 RILDPNPNSRIKIEKIMENSW 265
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 122 bits (306), Expect = 1e-27
Identities = 107/433 (24%), Positives = 194/433 (44%), Gaps = 81/433 (18%)
Query: 105 EEPEDVFPEQTE----LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVA 160
E P PE+ L Y L +++G G+F+KV+ + S G + VA
Sbjct: 2 ESPYPKSPEKITGTVLLGKYELGRRLGSGSFAKVH----VARSISTG---------ELVA 48
Query: 161 IKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYI 220
IK+I KQ+ ++ + ++++EI + + + N++ + ++ Y+
Sbjct: 49 IKIIDKQKTIDSGME-----------PRIIREIEAMRRLHNHPNVLKIHEVMATKSKIYL 97
Query: 221 IQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPID 280
+ E AGGE+F +++++ +E +R +QLA+A+ + H+ GI HRD+KP+NLL +
Sbjct: 98 VVEYAAGGELFTKLIRFGRLNESAARRYFQQLASALSFCHRDGIAHRDVKPQNLLLD--- 154
Query: 281 FIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSK-QIYQTNT---KTPC 336
+K++DFGLS +++N T C
Sbjct: 155 -------------------------------KQGNLKVSDFGLSALPEHRSNNGLLHTAC 183
Query: 337 GTVGYTAPEVVKDERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFL 395
GT YTAPEV+ Y + D W G L+ +L G+ PF D I + KI + +Y F
Sbjct: 184 GTPAYTAPEVIAQRGYDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIHKRDYRF- 242
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRR 455
P W IS A++ + KLL+ +P R + E ++ W L ++ + S E R
Sbjct: 243 -PSW--ISKPARSIIYKLLDPNPETRMSIEAVMGTVWFQK--SLEISEFQS--SVFELDR 295
Query: 456 HSHKHSRKAYKKNASLLYSPAAVAMRDAFDVSNAVQRIE-DDKRMTPGPKXXXXXXXLGV 514
K + K+++ + + +++ D+S +R + +KR T G+
Sbjct: 296 FLEKEA-----KSSNAITAFDLISLSSGLDLSGLFERRKRKEKRFTARVSAERVVEKAGM 350
Query: 515 LAEDAEAEIQYRE 527
+ E ++ +E
Sbjct: 351 IGEKLGFRVEKKE 363
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 122 bits (306), Expect = 1e-27
Identities = 82/281 (29%), Positives = 134/281 (47%), Gaps = 45/281 (16%)
Query: 159 VAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYY 218
VA+K+I K ++ E V +E+ I + +S +N+V F D E
Sbjct: 179 VAVKIIPKSKMTTA-----------IAIEDVRREVKILQALSGHKNLVQFYDAFEDNANV 227
Query: 219 YIIQELLAGGEIFGEIV-KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFE 277
YI EL GGE+ I+ + +SE+ ++ VI Q+ N V + H G+VHRD+KPEN L+
Sbjct: 228 YIAMELCEGGELLDRILARGGKYSENDAKPVIIQILNVVAFCHFQGVVHRDLKPENFLY- 286
Query: 278 PIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPC- 336
+S + +++L K DFGLS +
Sbjct: 287 -------------TSKEENSQL-----------------KAIDFGLSDFVRPDERLNDIV 316
Query: 337 GTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLR 396
G+ Y APEV+ Y+ + D+W +G + Y +LCG PF+ + + + + +F
Sbjct: 317 GSAYYVAPEVLH-RSYTTEADVWSIGVIAYILLCGSRPFWARTESGIFRAVLKADPSFDE 375
Query: 397 PWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYD 437
P W +S AK+ V++LL DP +R ++ Q L PW+ +Y+
Sbjct: 376 PPWPFLSSDAKDFVKRLLFKDPRRRMSASQALMHPWIRAYN 416
>Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 414
Score = 122 bits (305), Expect = 2e-27
Identities = 101/353 (28%), Positives = 156/353 (43%), Gaps = 79/353 (22%)
Query: 108 EDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQ 167
EDV+ Q ++ +GEGA ++V C N +S +E A+K+I KQ
Sbjct: 80 EDVYQLQEDV--------LGEGAHARV-------QTCINLITS------QEYAVKIIEKQ 118
Query: 168 QLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAG 227
+V +E+ + N++ I+F E E +Y++ E + G
Sbjct: 119 P--------------GHIRSRVFREVEMLYQCQGHRNVLELIEFFEEEDRFYLVFEKMRG 164
Query: 228 GEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKP 287
G I I K +F+E + V++ +A+A+ ++H GI HRD+KPEN+L E PN
Sbjct: 165 GSILSHIHKRRHFNELEASVVVQDVASALDFLHNKGIAHRDLKPENILCEH----PNQVS 220
Query: 288 KLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVV 347
++ D D G +KL G I TPCG+ Y APE+V
Sbjct: 221 PVKICD-----FDLG-----------SGIKLN--GDCSPISTPELLTPCGSAEYMAPELV 262
Query: 348 KD-----ERYSMQVDMWGVGCVLYTVLCGFPPFFDEK---------------IDVLTEKI 387
+ Y + D+W +G +LY +L G+PPF ++L E I
Sbjct: 263 EAFSEEASIYDKRCDLWSLGVILYILLSGYPPFVGRCGSDCGWDRGEACPACQNMLFESI 322
Query: 388 SRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLP 440
G+Y F W IS AK+ + KLL D +R ++ Q+LQ PW+ C P
Sbjct: 323 QEGKYEFPDKDWAHISCAAKDLISKLLVRDAKQRLSAAQVLQHPWVQG--CAP 373
>CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 521
Score = 122 bits (305), Expect = 2e-27
Identities = 76/266 (28%), Positives = 124/266 (46%), Gaps = 42/266 (15%)
Query: 186 AEQVLKEIAIHKIVSSGENIVSFIDFQESE----KYYYIIQELLAGGEIFGEIVKYTY-- 239
+++ +E+ +H + ++ EN+VS +D E+ K ++ E L GG++ +
Sbjct: 178 SQKARREVELHWLTNAHENVVSILDIYENTFDNVKCLLMVVEFLEGGDLLSQFESQGSIP 237
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
++E +IRQ+ NAV Y+H + I HRDIK EN+L
Sbjct: 238 YTEKKVGEIIRQIGNAVMYLHDMNIAHRDIKLENILCS---------------------- 275
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVDM 358
V KL D+G +K+ + ++PC T Y PEV+ ERY DM
Sbjct: 276 ---------GTGDNCVYKLGDYGFAKRPERNVLMESPCCTPFYAPPEVLGRERYDKSCDM 326
Query: 359 WGVGCVLYTVLCGFPPFFDEKIDVLT----EKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
W +G +Y +LCG+PPF+ K L+ +I+ Y F WD +S K+ +R LL
Sbjct: 327 WSLGVAMYILLCGYPPFYSMKGVALSPGMRSRIANAYYAFPHEEWDCVSKDTKDDIRCLL 386
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCLP 440
+P+ R T +L+ P + +P
Sbjct: 387 RTNPSDRLTIHELMATPLVTGEPIVP 412
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 121 bits (304), Expect = 2e-27
Identities = 86/322 (26%), Positives = 144/322 (44%), Gaps = 53/322 (16%)
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
+ N + + +EI I K++S N+++ + E++ Y++ E + GGE+F +V
Sbjct: 149 EHSNHSQTNPYGIEREIVIMKLISH-TNVMALFEVWENKSELYLVLEYVDGGELFDYLVS 207
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
E + H +Q+ V Y H I HRD+KPENLL + K R
Sbjct: 208 KGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLD--------KKNRR------ 253
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSK-QIYQTNTKTPCGTVGYTAPEVVKDERY-SM 354
+K+ADFG++ ++ KT CG+ Y +PE+V Y
Sbjct: 254 -------------------IKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGG 294
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
D+W G VL+ +L G PF D+ I L K+ G+Y +S A++ + K+L
Sbjct: 295 PSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMP----SNLSSEARDLISKIL 350
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSRKAYKKNASL--- 471
+DP KR T++++L+ P + YD LP + R K + K N+ L
Sbjct: 351 VIDPEKRITTQEILKHPLIKKYDDLP---------VNKVLRKMRKDNMARGKSNSDLHLL 401
Query: 472 -LYSPAAVAMRDAFDVSNAVQR 492
SP+ V + ++ ++ R
Sbjct: 402 NNVSPSIVTLHSKGEIDESILR 423
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 121 bits (304), Expect = 2e-27
Identities = 93/324 (28%), Positives = 152/324 (46%), Gaps = 68/324 (20%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKE---VAIKVIIKQQL 169
+Q L D+ + + +G+G F +VY +A++ K VA+KVI K+Q+
Sbjct: 15 KQWSLADFEIGRPLGKGKFGRVY----------------LAREAKSKYIVALKVIFKEQI 58
Query: 170 PNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGE 229
K Q+ +E+ I + + F F ++E+ + I+ E GGE
Sbjct: 59 E-----------KYKIHHQLRREMEIQTSLRHPNILRLFGWFHDNERIFLIL-EYAHGGE 106
Query: 230 IFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKL 289
++G + + + +E + I L+ A+ Y H ++HRDIKPENLL +
Sbjct: 107 LYGVLKQNGHLTEQQAATYIASLSQALAYCHGKCVIHRDIKPENLLLD------------ 154
Query: 290 RSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKD 349
EG +K+ADFG S Q KT CGT+ Y APE+V++
Sbjct: 155 ----------HEGR------------LKIADFGWSVQS-SNKRKTMCGTLDYLAPEMVEN 191
Query: 350 ERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNC 409
+ VD W +G + Y L G PPF E ++I + + +F P +S+ AKN
Sbjct: 192 RDHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSF--PLTPNVSEEAKNL 249
Query: 410 VRKLLEVDPAKRYTSEQLLQDPWL 433
+ +LL DP+KR + E+++Q PW+
Sbjct: 250 ISQLLVKDPSKRLSIEKIMQHPWI 273
>CE03584 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 761
Score = 121 bits (303), Expect = 3e-27
Identities = 92/332 (27%), Positives = 150/332 (44%), Gaps = 66/332 (19%)
Query: 124 QKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKT 183
+ +G GA+ V + C + S V E A+K++ KQ G+T
Sbjct: 205 EHLGSGAYGSV-------TTCKSIKSGV------EYAVKIVDKQ-------------GET 238
Query: 184 STAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSED 243
+ +++L+E+ I K NIV +D+ E E +Y++ E + GG + I++ YF+E+
Sbjct: 239 HSRKRILREVNIFKTCKDHPNIVQLLDWFEDETNFYLVMEKMRGGPLLQHILQRKYFTEE 298
Query: 244 LSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGV 303
+R V + ++ A+K+MH GI HRD+KPEN+L PN ++ D LD
Sbjct: 299 EARRVTKDISLALKFMHDRGIAHRDVKPENVLCTD----PNHVSPVKLCD-----LDLAS 349
Query: 304 FRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVV-----KDERYSMQVDM 358
RP LS+ + + +P G+ + APEVV +Y + D
Sbjct: 350 QRPPQHER---------HPLSQVASEPDLASPVGSAEFMAPEVVDAYVGDSLKYDKKCDT 400
Query: 359 WGVGCVLYTVLCGFPPF----------------FDEKIDVLTEKISRGEYTFLRPWWDQI 402
W +G +LY +L G+ PF ++ L +I G Y F W I
Sbjct: 401 WSLGVILYIMLAGYAPFQGMCDDEDCGWSEGKPCEDCQQDLFHRIQDGYYEFPEEEWGMI 460
Query: 403 SDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLN 434
S+ AK+ V LL+ DP R + + +P+ N
Sbjct: 461 SEEAKDLVSNLLKRDPVDRLVTVSFV-NPFAN 491
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 120 bits (301), Expect = 5e-27
Identities = 88/324 (27%), Positives = 156/324 (47%), Gaps = 54/324 (16%)
Query: 114 QTELKD-YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
Q +++D Y + +++G G F+ V + C + KE A K I K++L ++
Sbjct: 6 QEDVEDHYEMGEELGSGQFAIVRK-------CRQKGTG------KEYAAKFIKKRRL-SS 51
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG 232
+++G + E++ +E+ I + + NI++ D E++ +I EL++GGE+F
Sbjct: 52 SRRGVSR-------EEIEREVNILREIRH-PNIITLHDIFENKTDVVLILELVSGGELFD 103
Query: 233 EIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSS 292
+ + +ED + ++Q+ + V Y+H I H D+KPEN++ + +PNP+
Sbjct: 104 FLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKN-VPNPR------ 156
Query: 293 DDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDER 351
+KL DFG++ +I N K GT + APE+V E
Sbjct: 157 -----------------------IKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEP 193
Query: 352 YSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVR 411
++ DMW +G + Y +L G PF E IS Y F ++ S+ AK+ +R
Sbjct: 194 LGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIR 253
Query: 412 KLLEVDPAKRYTSEQLLQDPWLNS 435
+LL DP +R T Q L+ W+ +
Sbjct: 254 RLLVKDPKRRMTIAQSLEHSWIKA 277
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 577
Score = 120 bits (301), Expect = 5e-27
Identities = 84/279 (30%), Positives = 130/279 (46%), Gaps = 45/279 (16%)
Query: 157 KEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEK 216
++VA+KVI K ++ E V +E+ I + ++ +N+V F D E ++
Sbjct: 151 QDVAVKVIPKSKMTTA-----------IAIEDVRREVKILRALTGHKNLVQFYDAFEDDE 199
Query: 217 YYYIIQELLAGGEIFGEIVKYT-YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLL 275
YI+ EL GGE+ +I++ +SE ++ V+ Q+ + V Y H G+VHRD+KPEN L
Sbjct: 200 NVYIVMELCQGGELLDKILQRGGKYSEVDAKKVMIQILSVVAYCHLQGVVHRDLKPENFL 259
Query: 276 FEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP 335
F ++ D S+ L K DFGLS +
Sbjct: 260 F--------------TTKDESSPL-----------------KAIDFGLSDYVRPDERLND 288
Query: 336 C-GTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTF 394
G+ Y APEV+ Y + DMW +G + Y +LCG PF+ + + + E F
Sbjct: 289 IVGSAYYVAPEVLH-RTYGTEADMWSIGVIAYILLCGSRPFWARSESGIFRAVLKAEPNF 347
Query: 395 LRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
W +S A + V++LL D KR T+ Q L PWL
Sbjct: 348 EEAPWPSLSPDAVDFVKRLLNKDYRKRLTAAQALCHPWL 386
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 120 bits (300), Expect = 7e-27
Identities = 97/321 (30%), Positives = 147/321 (45%), Gaps = 69/321 (21%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
L Y + + +G G F+KVY N +G S VAIKVI K
Sbjct: 25 LGKYEMGRLLGHGTFAKVYLA----RNAQSGES---------VAIKVIDK---------- 61
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
EK K+ + +EI+I + V NIV + ++ Y + E + GGE+F ++ K
Sbjct: 62 -EKVLKSGLIAHIKREISILRRVRH-PNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAK 119
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
E+++R +QL +AV + H G+ HRD+KPENLL
Sbjct: 120 GR-LKEEMARKYFQQLISAVSFCHFRGVYHRDLKPENLL--------------------- 157
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGL---SKQIYQTNT-KTPCGTVGYTAPEVVKDERY 352
LDE +K++DFGL S QI Q T CGT Y APEV+ + Y
Sbjct: 158 --LDEN-----------GNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGY 204
Query: 353 -SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVR 411
+VD+W G +L+ ++ GF PF D + + +KI RG+ F P W + +
Sbjct: 205 DGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYRGD--FRCPRWFPVE--INRLLI 260
Query: 412 KLLEVDPAKRYTSEQLLQDPW 432
++LE P +R+T +++ W
Sbjct: 261 RMLETKPERRFTMPDIMETSW 281
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 119 bits (299), Expect = 9e-27
Identities = 91/319 (28%), Positives = 148/319 (45%), Gaps = 73/319 (22%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG--- 176
Y L +G G F KV G + +VA+K++ +Q++ + + G
Sbjct: 28 YLLGATLGTGTFGKVKIGEHQITRV-------------KVAVKILNRQKIKSLDVVGKIR 74
Query: 177 -DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV 235
+ +N K ++K +++++S+ +I ++I E ++GGE+F IV
Sbjct: 75 REIQNLKLFRHPHIIK---LYQVISTPSDI-------------FMIMEYVSGGELFDYIV 118
Query: 236 KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDP 295
K+ E +R +Q+ + V Y H+ IVHRD+KPENLL
Sbjct: 119 KHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLL-------------------- 158
Query: 296 STKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPEVVKDERYS- 353
LD + VK+ADFGLS + +T CG+ Y APEV+ + Y+
Sbjct: 159 ---LDHNMH-----------VKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAG 204
Query: 354 MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKL 413
+VD+W G +LY +LCG PF DE + L KI G + P + ++ N V ++
Sbjct: 205 PEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIF----PIPEYLNKQVVNLVCQM 260
Query: 414 LEVDPAKRYTSEQLLQDPW 432
L+VDP KR E++ + W
Sbjct: 261 LQVDPLKRANIEEIKKHEW 279
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 119 bits (298), Expect = 1e-26
Identities = 91/337 (27%), Positives = 156/337 (46%), Gaps = 56/337 (16%)
Query: 102 TPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAI 161
+P EP F +Q Y + +++G G F+ V + C ++ + E A
Sbjct: 8 SPNMEP---FKQQKVEDFYDIGEELGSGQFAIVKK-------CREKSTGL------EYAA 51
Query: 162 KVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYII 221
K I K+Q +++G + E++ +E++I + V N+++ D E+ +I
Sbjct: 52 KFIKKRQ-SRASRRGVSR-------EEIEREVSILRQVLH-HNVITLHDVYENRTDVVLI 102
Query: 222 QELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDF 281
EL++GGE+F + + SE+ + I+Q+ + V Y+H I H D+KPEN++
Sbjct: 103 LELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIML----- 157
Query: 282 IPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQ-TNTKTPCGTVG 340
LD+ + P +KL DFGL+ +I K GT
Sbjct: 158 -----------------LDKNIPIPH--------IKLIDFGLAHEIEDGVEFKNIFGTPE 192
Query: 341 YTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWD 400
+ APE+V E ++ DMW +G + Y +L G PF + I+ Y F ++
Sbjct: 193 FVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFS 252
Query: 401 QISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYD 437
Q S+ AK+ +RKLL + KR T ++ L+ PW+ D
Sbjct: 253 QTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVD 289
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 119 bits (298), Expect = 1e-26
Identities = 97/336 (28%), Positives = 157/336 (45%), Gaps = 70/336 (20%)
Query: 100 TTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEV 159
T+T Q++ Q ++ Y L + +G G F KV GI T+ QYK V
Sbjct: 8 TSTKQQQE---LKAQIKIGHYILKETLGVGTFGKVKVGIHETT------------QYK-V 51
Query: 160 AIKVIIKQQLPNTNKKGD-EKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYY 218
A+K++ +Q++ + + G + + + + I +++++S+ +I
Sbjct: 52 AVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHIIRLYQVISTPSDI------------- 98
Query: 219 YIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEP 278
++I E ++GGE+F IVK+ +R +Q+ + V Y H+ +VHRD+KPENLL
Sbjct: 99 FMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVVHRDLKPENLL--- 155
Query: 279 IDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCG 337
LDE VK+ADFGLS + + +T CG
Sbjct: 156 --------------------LDE-----------QNNVKIADFGLSNIMTDGDFLRTSCG 184
Query: 338 TVGYTAPEVVKDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLR 396
+ Y APEV+ + Y+ +VD+W G +LY +LCG PF DE + L KI G +
Sbjct: 185 SPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVF---- 240
Query: 397 PWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
P D + N + +L VDP KR T + ++ W
Sbjct: 241 PTPDFLERPIVNLLHHMLCVDPMKRATIKDVIAHEW 276
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 119 bits (298), Expect = 1e-26
Identities = 97/336 (28%), Positives = 157/336 (45%), Gaps = 70/336 (20%)
Query: 100 TTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEV 159
T+T Q++ Q ++ Y L + +G G F KV GI T+ QYK V
Sbjct: 8 TSTKQQQE---LKAQIKIGHYILKETLGVGTFGKVKVGIHETT------------QYK-V 51
Query: 160 AIKVIIKQQLPNTNKKGD-EKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYY 218
A+K++ +Q++ + + G + + + + I +++++S+ +I
Sbjct: 52 AVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHIIRLYQVISTPSDI------------- 98
Query: 219 YIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEP 278
++I E ++GGE+F IVK+ +R +Q+ + V Y H+ +VHRD+KPENLL
Sbjct: 99 FMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVVHRDLKPENLL--- 155
Query: 279 IDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCG 337
LDE VK+ADFGLS + + +T CG
Sbjct: 156 --------------------LDE-----------QNNVKIADFGLSNIMTDGDFLRTSCG 184
Query: 338 TVGYTAPEVVKDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLR 396
+ Y APEV+ + Y+ +VD+W G +LY +LCG PF DE + L KI G +
Sbjct: 185 SPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVF---- 240
Query: 397 PWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
P D + N + +L VDP KR T + ++ W
Sbjct: 241 PTPDFLERPIVNLLHHMLCVDPMKRATIKDVIAHEW 276
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 118 bits (296), Expect = 2e-26
Identities = 97/418 (23%), Positives = 185/418 (44%), Gaps = 78/418 (18%)
Query: 54 SVRVIDREAGXXXXXXXXXXXHHVQIVQGKDGTSQEENTYDESSDATTTPQEEPEDVFPE 113
++R++ +++G I QGK+ +Q +N + A Q
Sbjct: 40 TLRMMGKQSGPRNDQQQAPLMPPADIKQGKEQAAQRQNDASRPNGAVELRQFH------- 92
Query: 114 QTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQ------ 167
+ L D+ ++ +G G+ KV V +Q KE+ + I+ +
Sbjct: 93 RRSLGDWEFLETVGAGSMGKV--------------KLVKHRQTKEICVIKIVNRASKAYL 138
Query: 168 ----QLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGE-----NIVSFIDFQESEKYY 218
LP+ + + + +++ ++ + S G+ +I + ++
Sbjct: 139 HKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHF 198
Query: 219 YIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEP 278
Y++ E ++GG++ I+++ E +R R +A+A++Y+H IVHRD+K EN++
Sbjct: 199 YMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIM--- 255
Query: 279 IDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-YQTNTKTPCG 337
+ SS + +K+ DFGLS Y+ T CG
Sbjct: 256 ----------ISSSGE---------------------IKIIDFGLSNIFDYRKQLHTFCG 284
Query: 338 TVGYTAPEVVKDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLR 396
++ + APE++K + Y+ +VD+W G VLY ++CG PF DE +L EKI +G+ +
Sbjct: 285 SLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYP- 343
Query: 397 PWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLN-SYDC-LPSADHSNAPSTGE 452
+S + + +++ VDP +R T + +++ PW+N YD PS + P T E
Sbjct: 344 ---SHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYDFKAPSYVPNRVPLTPE 398
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 118 bits (295), Expect = 3e-26
Identities = 93/316 (29%), Positives = 139/316 (43%), Gaps = 66/316 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + IGEG F+KV N G + VAIK++ K +
Sbjct: 11 YEVGRTIGEGTFAKV----KFARNTDTGDN---------VAIKIMAKSTIL--------- 48
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
K +Q+ +EI+I KIV NIV + S YI+ E + GGE+F IV
Sbjct: 49 --KNRMVDQIKREISIMKIVRH-PNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGR 105
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
E SR +QL +AV + H G+ HRD+KPENLL +
Sbjct: 106 LEESESRKYFQQLVDAVAHCHCKGVYHRDLKPENLLLD---------------------- 143
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLS--KQIYQTNTKTPCGTVGYTAPEVVKDERY-SMQV 356
+K++DFGLS Q +T CGT Y APEV+ + Y
Sbjct: 144 ------------TNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGYDGSAA 191
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D+W G +L+ +L G+ PF + + L KI+ E++ PW+ S K + ++L+
Sbjct: 192 DIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFS-CPPWF---SAEVKFLIHRILDP 247
Query: 417 DPAKRYTSEQLLQDPW 432
+P R + + +DPW
Sbjct: 248 NPKTRIQIQGIKKDPW 263
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 117 bits (294), Expect = 3e-26
Identities = 85/309 (27%), Positives = 143/309 (45%), Gaps = 56/309 (18%)
Query: 157 KEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEK 216
++VA+KVI K +L T + +E+ K+V NIV + +++
Sbjct: 40 EKVAVKVIDKTKLD------------TLATGHLFQEVRCMKLVQH-PNIVRLYEVIDTQT 86
Query: 217 YYYIIQELLAGGEIFGEIVKYTY-FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLL 275
Y+I EL G++F I+K+ +EDL + Q+ +A+ Y H+L +VHRD+KPEN++
Sbjct: 87 KLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKLHVVHRDLKPENVV 146
Query: 276 FEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK-- 333
F +VKL DFG S + +Q K
Sbjct: 147 F---------------------------------FEKQGLVKLTDFGFSNK-FQPGKKLT 172
Query: 334 TPCGTVGYTAPEVVKDERYSMQ-VDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEY 392
T CG++ Y+APE++ + Y VD+W +G +L+ ++CG PPF + I +Y
Sbjct: 173 TSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKY 232
Query: 393 TFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGE 452
T +S K+ + ++L+ DP +R + E++ PWL D P+ + N P
Sbjct: 233 TVP----SHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKY-NIPLVSY 287
Query: 453 KRRHSHKHS 461
K +H+
Sbjct: 288 KNLSEEEHN 296
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 117 bits (293), Expect = 4e-26
Identities = 90/342 (26%), Positives = 152/342 (44%), Gaps = 68/342 (19%)
Query: 114 QTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTN 173
+T KDY +GEG F++ + Q K+ + ++ + + +
Sbjct: 76 KTRGKDYHRGHFLGEGGFARCF-------------------QIKDDSGEIFAAKTVAKAS 116
Query: 174 KKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGE 233
K ++ T +++L EI IHK +S NIV FID E + YI+ E+ G +
Sbjct: 117 IKSEK------TRKKLLSEIQIHKSMSH-PNIVQFIDCFEDDSNVYILLEICPNGSLMEL 169
Query: 234 IVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSD 293
+ + +E R Q+ A+KYMH ++HRD+K N+ F+
Sbjct: 170 LKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFD---------------- 213
Query: 294 DPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK--TPCGTVGYTAPEVV--KD 349
+K+ DFGL+ + + + T CGT Y APEV+ K
Sbjct: 214 ------------------SNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKH 255
Query: 350 ERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNC 409
+S +VD+W +G +LY +L G PPF ++ + E+I +++F R ISD K
Sbjct: 256 SGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFSFPRD--KPISDEGKIL 313
Query: 410 VRKLLEVDPAKRYTSEQLLQDPWLNSY--DCLPSADHSNAPS 449
+R +L +DP +R + +++ W +PS S AP+
Sbjct: 314 IRDILSLDPIERPSLTEIMDYVWFRGTFPPSIPSTVMSEAPN 355
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 117 bits (293), Expect = 4e-26
Identities = 86/318 (27%), Positives = 146/318 (45%), Gaps = 61/318 (19%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y ++++G G+ SKV G S ++VAIK+I P G+
Sbjct: 58 YRFVKQLGTGSSSKVVLGRDVRSG-------------EKVAIKII-----PRRVNGGETG 99
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
+ + ++V +E+ I +++ +I +F S +Y++I E + G +++ I+
Sbjct: 100 DMEMRCDQRVFREVIISSVLNH-PHIARLKNFLYSPTHYFLIFEYVKGRQLYDIIISSGP 158
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
E + RQL +A+ Y+H+ +VHRD+K EN+L + D
Sbjct: 159 LKEKEGQRYFRQLLSAIDYIHRNSVVHRDLKIENILIDENDN------------------ 200
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT--KTPCGTVGYTAPEVVKDERY-SMQV 356
VKL DFGLS Y T T CG++ + APE+++ +RY ++
Sbjct: 201 ----------------VKLIDFGLSN-FYDNKTLLNTFCGSLYFAAPELLQGQRYCGPEI 243
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D+W +G VLY +LCG PF DE + L KI ++ F + IS A +R ++
Sbjct: 244 DVWSLGVVLYAILCGCVPFDDEDVQGLQAKIMDADFKFCK----TISREAMELIRGMIVA 299
Query: 417 DPAKRYTSEQLLQDPWLN 434
P+ R Q++ W+N
Sbjct: 300 QPSSRMGLSQVIGSEWVN 317
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 117 bits (293), Expect = 4e-26
Identities = 101/353 (28%), Positives = 155/353 (43%), Gaps = 76/353 (21%)
Query: 82 GKDGTSQEENTYDESSDATTTPQEEPEDVFPEQ-----------TELKDYTLIQKIGEGA 130
G+ + E T D T ++E + F Q L+++ ++ +G+G
Sbjct: 136 GEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGT 195
Query: 131 FSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVL 190
F KV C A++ K AIK++ K+ + ++ T T +VL
Sbjct: 196 FGKVIL-------CREKATA------KLYAIKILKKEVIIQKDEVAH-----TLTESRVL 237
Query: 191 KEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIR 250
K ++S + FQ +++ +++Q + GGE+F + F+ED +R
Sbjct: 238 KSTNHPFLISLKYS------FQTNDRLCFVMQ-YVNGGELFWHLSHERIFTEDRTRFYGA 290
Query: 251 QLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXX 310
++ +A+ Y+H GI++RD+K ENLL + I
Sbjct: 291 EIISALGYLHSQGIIYRDLKLENLLLDKDGHI---------------------------- 322
Query: 311 XXXXVVKLADFGLSKQ--IYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTV 368
K+ADFGL K+ Y TKT CGT Y APEV+ D Y VD WG G V+Y +
Sbjct: 323 ------KVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEM 376
Query: 369 LCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKR 421
+CG PF++ DVL I E F R I+D AKN + LL DP KR
Sbjct: 377 ICGRLPFYNRDHDVLFTLILVEEVKFPR----NITDEAKNLLAGLLAKDPKKR 425
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 117 bits (292), Expect = 6e-26
Identities = 84/317 (26%), Positives = 134/317 (41%), Gaps = 63/317 (19%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
+ D+ + + +G+G F VY T + VAIKV+ K QL + +
Sbjct: 27 INDFEIGRPLGKGKFGSVYLARTKTGHF-------------HVAIKVLFKSQLISGGVE- 72
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
Q+ +EI I ++ NI+ + K Y++ E GGE++ ++
Sbjct: 73 ----------HQLEREIEIQSHLNH-PNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTV 121
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
FSE + + ++A+A+ Y H+ ++HRDIKPENLL
Sbjct: 122 SKRFSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLI-------------------- 161
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQV 356
+K+ DFG S +T CGT+ Y PE+V +S V
Sbjct: 162 --------------GSQGELKIGDFGWSVHAPSNKRQTMCGTMDYLPPEMVNGADHSDAV 207
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D+W +G + Y L G PPF E I +T+ D + GA++ + +LL V
Sbjct: 208 DLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYP----DSVKKGARDLIGRLLVV 263
Query: 417 DPAKRYTSEQLLQDPWL 433
DP R T EQ+ + W+
Sbjct: 264 DPKARCTLEQVKEHYWI 280
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 116 bits (290), Expect = 1e-25
Identities = 87/318 (27%), Positives = 141/318 (43%), Gaps = 64/318 (20%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
L D+ L +K+G+G F KVY C S+ A+KV+ K+++ N +
Sbjct: 101 LDDFELGKKLGKGKFGKVY--------CVRHRSTGYI-----CALKVMEKEEIIKYNLQ- 146
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
+Q +E+ I ++ N+ + EK Y++ E L GE++ +
Sbjct: 147 ----------KQFRREVEIQTSLNH-PNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRL 195
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
+ F++ L+ I Q+ANA+ YMH+ I+HRDIKPEN+L
Sbjct: 196 HGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILI-------------------- 235
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSK-QIYQTNTKTPCGTVGYTAPEVVKDERYSMQ 355
V+KL DFG S + KT CGT+ Y +PE+V+ Y
Sbjct: 236 --------------GFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHT 281
Query: 356 VDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLE 415
+D W +G + + +L G PPF +E D ++I+ + IS A++ + KLL+
Sbjct: 282 IDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMP----SNISQDAQDLILKLLK 337
Query: 416 VDPAKRYTSEQLLQDPWL 433
DP R + PW+
Sbjct: 338 YDPKDRMRLGDVKMHPWI 355
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 116 bits (290), Expect = 1e-25
Identities = 85/329 (25%), Positives = 150/329 (44%), Gaps = 52/329 (15%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+Y L + IG G+ KV + A ++ + + ++ K T E
Sbjct: 124 NYVLGKTIGAGSMGKV-KVAHHLKTGEQFAIKIVTRLHPDIT-KAKAAASAEATKAAQSE 181
Query: 179 KNGKTSTA-EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKY 237
KN + T E L + H + ++ + +YY++ E + GG++ I+ +
Sbjct: 182 KNKEIRTVREAALSTLLRHPYICEARDVYI------TNSHYYMVFEFVDGGQMLDYIISH 235
Query: 238 TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPST 297
E +R +RQ+ +A+ Y+HQ +VHRD+K EN+L ++ D
Sbjct: 236 GKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILIS------------KTGD---- 279
Query: 298 KLDEGVFRPXXXXXXXXVVKLADFGLSKQIY--QTNTKTPCGTVGYTAPEVVKDERY-SM 354
+K+ DFGLS +Y Q+ +T CG++ + APE++ + Y
Sbjct: 280 ------------------IKIIDFGLSN-LYRRQSRLRTFCGSLYFAAPELLNAQPYIGP 320
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+VD+W G VLY ++CG PF D+ + L KI +G + +S K + ++L
Sbjct: 321 EVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYP----SYLSSDCKGLLSRML 376
Query: 415 EVDPAKRYTSEQLLQDPW-LNSYDCLPSA 442
DP KR T E++L PW + +Y+ P++
Sbjct: 377 VTDPLKRATLEEVLNHPWMIRNYEGPPAS 405
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 116 bits (290), Expect = 1e-25
Identities = 80/277 (28%), Positives = 126/277 (44%), Gaps = 45/277 (16%)
Query: 159 VAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYY 218
VA+K+I K ++ + + E V +E+ + K +S ++V F D E
Sbjct: 171 VAVKIISKSKMTSA-----------LSIEDVRREVKLLKALSGHSHMVKFYDVFEDSDNV 219
Query: 219 YIIQELLAGGEIFGEIV-KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFE 277
+++ EL GGE+ I+ + + E ++ ++ Q+ +A + H G+VHRD+KPEN LF
Sbjct: 220 FVVMELCEGGELLDSILARGGRYPEAEAKRILVQILSATAFFHLQGVVHRDLKPENFLF- 278
Query: 278 PIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-YQTNTKTPC 336
T +E V+K+ DFGLS +
Sbjct: 279 -------------------TSKNEDA-----------VLKVIDFGLSDYARFDQRLNDVV 308
Query: 337 GTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLR 396
G+ Y APEV+ YS + D+W +G + Y +LCG PF+ + + R F
Sbjct: 309 GSAYYVAPEVLH-RSYSTEADIWSIGVISYILLCGSRPFYGRTESAIFRCVLRANPNFDD 367
Query: 397 PWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
W IS AK+ V++LL D KR T+ Q L PWL
Sbjct: 368 LPWPSISPIAKDFVKRLLNKDHRKRMTAAQALAHPWL 404
>Hs21361101 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 465
Score = 115 bits (289), Expect = 1e-25
Identities = 102/365 (27%), Positives = 160/365 (42%), Gaps = 74/365 (20%)
Query: 108 EDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQ 167
ED++ +EL +GEGA++KV GA S+ Q KE A+K+I KQ
Sbjct: 45 EDMYKLTSEL--------LGEGAYAKV-----------QGAVSL--QNGKEYAVKIIEKQ 83
Query: 168 QLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAG 227
+ +V +E+ +NI+ I+F E + +Y++ E L G
Sbjct: 84 A--------------GHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQG 129
Query: 228 GEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMH---QLGIVH---RDIKPENLLFEPIDF 281
G I I K +F+E + V+R +A A+ ++H ++ + H + P L P
Sbjct: 130 GSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSL 189
Query: 282 IPNPKPKLRSSDDPSTKLDEGVFRPX----XXXXXXXVVKLADFGLSKQIYQTNT----- 332
+ P S +T + +P VK+ DF L + N+
Sbjct: 190 GSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPIT 249
Query: 333 ----KTPCGTVGYTAPEVVK---DER--YSMQVDMWGVGCVLYTVLCGFPPFFD------ 377
TPCG+ Y APEVV+ D+ Y + D+W +G VLY +L G+PPF
Sbjct: 250 TPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADC 309
Query: 378 --EKIDV-------LTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLL 428
++ +V L E I G+Y F W IS AK+ + KLL D +R ++ Q+L
Sbjct: 310 GWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVL 369
Query: 429 QDPWL 433
Q PW+
Sbjct: 370 QHPWV 374
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 115 bits (288), Expect = 2e-25
Identities = 95/372 (25%), Positives = 164/372 (43%), Gaps = 79/372 (21%)
Query: 75 HHVQIVQGKDGTSQEENTYDESSDATTTP-QEEPEDVFPEQTE--LKDYTLIQKIGEGAF 131
++V + GK+ + ++ S P P P+ E + + + + +G+G F
Sbjct: 70 NNVSLANGKENKRTSNSKFNSSLRKIEEPIAGVPSSAGPQWREFHIGMFEIGKPLGKGKF 129
Query: 132 SKVYRGIPSTSNCSNGASSVIAQQYKE---VAIKVIIKQQLPNTNKKGDEKNGKTSTAEQ 188
+VY +A++ K VA+K + K +L ++ +Q
Sbjct: 130 GRVY----------------LAKEKKTGFIVALKTLHKSELV-----------QSKIEKQ 162
Query: 189 VLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHV 248
V +EI I + +NI+ EK Y+I E GE++ + + FSE+++
Sbjct: 163 VRREIEIQSNLRH-KNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKY 221
Query: 249 IRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXX 308
I Q+ANA+ Y+H+ ++HRDIKPEN+L ID
Sbjct: 222 IFQMANALSYLHKKHVIHRDIKPENILLG-ID---------------------------- 252
Query: 309 XXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTV 368
+KL+DFG S T CGT+ Y PE+V+ + ++ +VD+W +G + Y
Sbjct: 253 -----GEIKLSDFGWSVHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVDLWSLGVLTYEF 307
Query: 369 LCGFPPFFDEKIDVLT----EKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTS 424
L G PPF D T K+ +F+ P A++ + +LL+ +P KR +
Sbjct: 308 LVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPP-------DARDLISRLLQHNPEKRMSL 360
Query: 425 EQLLQDPWLNSY 436
EQ+++ PW+ Y
Sbjct: 361 EQVMRHPWIVKY 372
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 114 bits (286), Expect = 3e-25
Identities = 85/302 (28%), Positives = 138/302 (45%), Gaps = 58/302 (19%)
Query: 158 EVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKY 217
EVAIK+I K QL N E++ +E+ I K++ +I+ E++
Sbjct: 45 EVAIKIIDKSQLDAVN------------LEKIYREVQIMKMLDH-PHIIKLYQVMETKSM 91
Query: 218 YYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFE 277
Y++ E GEIF + + +E +R Q+ +AV Y H IVHRD+K ENLL
Sbjct: 92 LYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLL-- 149
Query: 278 PIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPC 336
LD + +K+ADFG T C
Sbjct: 150 ---------------------LDNNMN-----------IKIADFGFGNFFKSGELLATWC 177
Query: 337 GTVGYTAPEVVKDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFL 395
G+ Y APEV + ++Y Q+D+W +G VLY ++CG PF + +L +++ G +
Sbjct: 178 GSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRI- 236
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL-----NSYDCLPSADHSNAPST 450
P++ +S+ ++ +R++L +DP+KR T Q+ + W+ L + N PS
Sbjct: 237 -PYF--MSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSI 293
Query: 451 GE 452
GE
Sbjct: 294 GE 295
>At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 575
Score = 114 bits (286), Expect = 3e-25
Identities = 89/291 (30%), Positives = 128/291 (43%), Gaps = 55/291 (18%)
Query: 157 KEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEK 216
K A K I K+ L + +K E V EI I VS NIV E
Sbjct: 46 KSYACKSIPKRTLSSEEEK-----------EAVKTEIQIMDHVSGQPNIVQIKGSYEDNN 94
Query: 217 YYYIIQELLAGGEIFGEI----VKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPE 272
+I+ EL GGE+F +I ++Y+SE + + R + NAVK H L +VHRD+KPE
Sbjct: 95 SIHIVMELCGGGELFDKIDALVKSHSYYSEKDAAGIFRSIVNAVKICHSLDVVHRDLKPE 154
Query: 273 NLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT 332
N LF SS D + L K DFG S I + T
Sbjct: 155 NFLF--------------SSKDENAML-----------------KAIDFGCSVYIKEGKT 183
Query: 333 -KTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPF-------FDEKIDVLT 384
+ G+ Y APEV++ Y ++D+W G +LY +L G PPF + ++
Sbjct: 184 FERVVGSKYYIAPEVLEGS-YGKEIDIWSAGVILYILLSGVPPFQTGIESIIVSTLCIVD 242
Query: 385 EKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNS 435
+I F W IS AK+ + K+L P +R ++ +L+ PW+ S
Sbjct: 243 AEIKECRLDFESQPWPLISFKAKHLIGKMLTKKPKERISAADVLEHPWMKS 293
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 114 bits (286), Expect = 3e-25
Identities = 97/345 (28%), Positives = 152/345 (43%), Gaps = 70/345 (20%)
Query: 94 DESSDATTTPQEEPEDVFPEQTELKD-YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVI 152
D D +PQ P L Y L + +G G F+KVY N +G
Sbjct: 47 DTDKDGNISPQSPRSPRSPRNNILMGKYELGKLLGHGTFAKVYLA----QNIKSG----- 97
Query: 153 AQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQ 212
+VAIKVI K EK K+ + +EI+I + V IV +
Sbjct: 98 ----DKVAIKVIDK-----------EKIMKSGLVAHIKREISILRRVRH-PYIVHLFEVM 141
Query: 213 ESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPE 272
++ Y + E + GGE+F + K E+ +R +QL ++V + H G+ HRD+KPE
Sbjct: 142 ATKSKIYFVMEYVGGGELFNTVAKGR-LPEETARRYFQQLISSVSFCHGRGVYHRDLKPE 200
Query: 273 NLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLS---KQIYQ 329
NLL + +K++DFGLS +Q+ Q
Sbjct: 201 NLLLD----------------------------------NKGNLKVSDFGLSAVAEQLRQ 226
Query: 330 TNT-KTPCGTVGYTAPEVVKDERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKI 387
T CGT Y APEV+ + Y + + D+W G +L+ ++ G PF+D+ I V+ +KI
Sbjct: 227 DGLCHTFCGTPAYIAPEVLTRKGYDAAKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKI 286
Query: 388 SRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
+GE F P W S + +LL+ +P R T +++++ W
Sbjct: 287 YKGE--FRCPRW--FSSDLVRLLTRLLDTNPDTRITIPEIMKNRW 327
>CE09360 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2783
Score = 114 bits (285), Expect = 4e-25
Identities = 91/365 (24%), Positives = 166/365 (44%), Gaps = 65/365 (17%)
Query: 88 QEENTYDESSDATTTPQEEPEDVFPEQTELK-DYTLIQKIGEGAFSKVYRGIPSTSNCSN 146
QE Y+ + + + + D+ +L+ Y + +++G+GA+ VYR +
Sbjct: 162 QESVDYERVAKDSEPSEYKTIDIHRLPNDLQAKYIIHEELGKGAYGTVYRATEKATG--- 218
Query: 147 GASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIV 206
K A K++ Q P K E V+ EI++ + E ++
Sbjct: 219 ----------KTWAAKMV--QVRPGVKK------------ENVIHEISMMNQLHH-EKLL 253
Query: 207 SFIDFQESEKYYYIIQELLAGGEIFGEIVKY-TYFSEDLSRHVIRQLANAVKYMHQLGIV 265
+ + + ++I+E ++GGE+F +I++ + SE+ R + Q+ V +MH+ IV
Sbjct: 254 NLHEAFDMGNEMWLIEEFVSGGELFEKILEDDSLMSEEEVRDYMHQILLGVSHMHKNQIV 313
Query: 266 HRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSK 325
H D+KPEN+L K ++S++ +K+ DFGL++
Sbjct: 314 HLDLKPENILL-----------KAKNSNE---------------------LKIIDFGLAR 341
Query: 326 QIY-QTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLT 384
++ + + K GT + APEVV + + DMW VG + Y +L G PF + +
Sbjct: 342 KLDPKKSVKLLFGTPEFCAPEVVNYQPVGLSTDMWTVGVISYVLLSGLSPFLGDSDEDTL 401
Query: 385 EKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADH 444
+S ++ F P WD +SD AK+ + +L+ D KR + + L+ PW+ P D
Sbjct: 402 ANVSASDWDFDDPSWDDVSDLAKDFICRLMIKDKRKRMSVQDALRHPWITKMQ--PKLDK 459
Query: 445 SNAPS 449
S P+
Sbjct: 460 SGVPA 464
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 114 bits (284), Expect = 5e-25
Identities = 88/289 (30%), Positives = 132/289 (45%), Gaps = 48/289 (16%)
Query: 157 KEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQ---VLKEIAIHKIVSSGENIVSFIDFQE 213
+E A+KVI K N G G T+ + +EI I K+++ N++ D E
Sbjct: 43 QEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIEREIIIMKLLNH-PNVLRLYDVWE 101
Query: 214 SEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPEN 273
+ Y++ E GE+F +V+ E + RQ+ V Y H LGIVHRD+KPEN
Sbjct: 102 TNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPEN 161
Query: 274 LLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK 333
LL + +K+ADFG++ +T K
Sbjct: 162 LLLD----------------------------------HKYNIKIADFGMAA--LETEGK 185
Query: 334 ---TPCGTVGYTAPEVVKDERYS-MQVDMWGVGCVLYTVLCGFPPFFDE--KIDVLTEKI 387
T CG+ Y APE+V Y D+W G +L+ +L G PF +E I L K+
Sbjct: 186 LLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKV 245
Query: 388 SRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSY 436
+GE+ P D+IS A++ +RK+L VDP +R + +L+ P L Y
Sbjct: 246 QKGEFEM--PSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKY 292
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 114 bits (284), Expect = 5e-25
Identities = 82/306 (26%), Positives = 138/306 (44%), Gaps = 64/306 (20%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
L D+ I+ +G G+F +V S A+K++ KQ++
Sbjct: 49 LDDFDRIKTLGTGSFGRVMLVKHKQSG-------------NYYAMKILDKQKVV------ 89
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
K E L E I + + + F+++ Y ++ E ++GGE+F + +
Sbjct: 90 -----KLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVL-EFISGGEMFSHLRR 143
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
FSE SR Q+ A +Y+H L +++RD+KPENLL + ++
Sbjct: 144 IGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYL-------------- 189
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQV 356
K+ DFG +K++ + T T CGT Y APE++ + Y+ V
Sbjct: 190 --------------------KITDFGFAKRV-KGRTWTLCGTPEYLAPEIILSKGYNKAV 228
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D W +G ++Y + G+PPFF ++ + EKI G+ F + +++ D KN LL+V
Sbjct: 229 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKN----LLQV 284
Query: 417 DPAKRY 422
D KRY
Sbjct: 285 DLTKRY 290
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 114 bits (284), Expect = 5e-25
Identities = 82/306 (26%), Positives = 138/306 (44%), Gaps = 64/306 (20%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
L D+ I+ +G G+F +V S A+K++ KQ++
Sbjct: 49 LDDFDRIKTLGTGSFGRVMLVKHKQSG-------------NYYAMKILDKQKVV------ 89
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
K E L E I + + + F+++ Y ++ E ++GGE+F + +
Sbjct: 90 -----KLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVL-EFISGGEMFSHLRR 143
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
FSE SR Q+ A +Y+H L +++RD+KPENLL + ++
Sbjct: 144 IGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYL-------------- 189
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQV 356
K+ DFG +K++ + T T CGT Y APE++ + Y+ V
Sbjct: 190 --------------------KITDFGFAKRV-KGRTWTLCGTPEYLAPEIILSKGYNKAV 228
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D W +G ++Y + G+PPFF ++ + EKI G+ F + +++ D KN LL+V
Sbjct: 229 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKN----LLQV 284
Query: 417 DPAKRY 422
D KRY
Sbjct: 285 DLTKRY 290
>7299507 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 1142
Score = 114 bits (284), Expect = 5e-25
Identities = 97/412 (23%), Positives = 169/412 (40%), Gaps = 73/412 (17%)
Query: 87 SQEENTYDESSDATT-TPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCS 145
S E+ + +ESS+A T E ++ + E++ ++I S ++ + +
Sbjct: 64 SSEDVSGNESSEAPNMTEVERQAELNRHKEEMQKKRRKKRISSSLHSSTFQELYKLTGEI 123
Query: 146 NGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENI 205
G + Y V V I L K D+ G +V +E+ I
Sbjct: 124 LGEGA-----YASVQTCVNIYTDLEYAVKVIDKIPGHARA--RVFREVETFHHCQGHLGI 176
Query: 206 VSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIV 265
+ I+F E ++ +Y++ E + GG + I ++ FSE + +I+++A+ + ++H+ GI
Sbjct: 177 LQLIEFFEDDEKFYLVFEKINGGPLLSRIQEHICFSEHEASQIIKEIASGLDFLHKKGIA 236
Query: 266 HRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSK 325
HRD+KPEN+L D + +K+ DF L
Sbjct: 237 HRDLKPENILCVKTDSL-------------------------------CPIKICDFDLGS 265
Query: 326 QIYQTNT----------KTPCGTVGYTAPEVV-----KDERYSMQVDMWGVGCVLYTVLC 370
I T TP G+ + APEVV + Y + D+W +G + Y +LC
Sbjct: 266 GIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAHYYDKRCDLWSLGVIAYILLC 325
Query: 371 GFPPFFDEK---------------IDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLE 415
G+PPF ++L E I G ++F W +SD AK+ + LL
Sbjct: 326 GYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDEAKDLISNLLV 385
Query: 416 VDPAKRYTSEQLLQDPWLNSYDCLPSAD----HSNAPSTGEKRRHSHKHSRK 463
+ R ++E +L PW+ + P A A T R +H+ +R+
Sbjct: 386 KKASNRLSAEAVLNHPWIRMCEQEPPASKHGRRHKALQTPSNIRRNHQSARE 437
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 113 bits (283), Expect = 6e-25
Identities = 84/318 (26%), Positives = 140/318 (43%), Gaps = 63/318 (19%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
D+ + + +G+G F VY + + + + VA+KV+ K Q+ E
Sbjct: 8 DFEIGRPLGKGKFGNVYL-------------ARLKESHFIVALKVLFKSQI--------E 46
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
K G Q+ +EI I + NI+ ++ + Y+I E GE++ E+ K
Sbjct: 47 KEG---LEHQLRREIEIQAHLQH-PNILRLYNYFHDARRVYLILEYAPRGELYKELQKSE 102
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
E + +I ++A+A+ Y H ++HRDIKPENLL
Sbjct: 103 KLDEQRTATIIEEVADALTYCHDKKVIHRDIKPENLLLG--------------------- 141
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDM 358
FR VK+ADFG S KT CGT+ Y PE+++ Y +VD+
Sbjct: 142 -----FRGE--------VKIADFGWSVHTPLPERKTMCGTLDYLPPEMIEGRTYDEKVDL 188
Query: 359 WGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDP 418
W +G + Y +L G+PPF +I + + F + GA++ + +LL P
Sbjct: 189 WCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPL----SMPLGARDLISRLLRYQP 244
Query: 419 AKRYTSEQLLQDPWLNSY 436
+R Q+L+ PW+ ++
Sbjct: 245 LERLPLAQILKHPWVQAH 262
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 113 bits (283), Expect = 6e-25
Identities = 92/361 (25%), Positives = 161/361 (44%), Gaps = 80/361 (22%)
Query: 87 SQEENTYDESSDATTTPQEEPEDVFPEQTE---------LKDYTLIQKIGEGAFSKVYRG 137
S +ENT D ED P++ + L D+ + + +G+G F V+
Sbjct: 2 SGKENTAPVIDDQKAEVISLTEDSRPQRVDQAREESCWSLDDFDVGRPLGKGKFGNVF-- 59
Query: 138 IPSTSNCSNGASSVIAQQYKE---VAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIA 194
I+++ K +A+KV+ K QL + + Q+ +EI
Sbjct: 60 --------------ISREKKTKRIIALKVLFKTQLL-----------QLGVSHQLKREIE 94
Query: 195 IHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT--YFSEDLSRHVIRQL 252
I + NI++ + +K ++I + + GE+F + +E ++ +RQL
Sbjct: 95 IQYHLRH-PNILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQL 153
Query: 253 ANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXX 312
ANA+ Y H G++HRDIKPENLL + +KL+
Sbjct: 154 ANALHYCHSKGVIHRDIKPENLLLD-------------------SKLN------------ 182
Query: 313 XXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGF 372
+KLADFG S + T CGT+ Y APE+V ++ + VD+W +G +L+ +L G+
Sbjct: 183 ---LKLADFGWSVVADHSKRHTLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLVGY 239
Query: 373 PPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
PF ++ D L +I E P ++DGA + + +++ +P +R ++ PW
Sbjct: 240 APFANQTGDKLIARIK--ECKIYIP--SVVTDGAASLINAIIKKEPQERLPLVDIMAHPW 295
Query: 433 L 433
+
Sbjct: 296 I 296
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 113 bits (282), Expect = 8e-25
Identities = 91/321 (28%), Positives = 143/321 (44%), Gaps = 68/321 (21%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEV-AIKVIIKQQLPNTNKKGDE 178
YT IGEG F++ +R + Y + A KVI K+ L N K
Sbjct: 41 YTRYDCIGEGGFARCFR---------------VKDNYGNIYAAKVIAKRSLQNDKTK--- 82
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
++ EI +H+ +S NIV FID E Y+I EL + + K
Sbjct: 83 --------LKLFGEIKVHQSMSH-PNIVGFIDCFEDSTNIYLILELCEHKSLMELLRKRK 133
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
+E R+++ Q+ A+KYMH+ ++HRD+K N++
Sbjct: 134 QLTEPEVRYLMMQILGALKYMHKKRVIHRDLKLGNIM----------------------- 170
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK--TPCGTVGYTAPEVV--KDERYSM 354
LDE VK+ DFGL+ + + T CGT Y APE++ E +S
Sbjct: 171 LDES-----------NNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGHSF 219
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+VD+W G V+Y +L G PPF D+++ + KI Y+F P IS AK+ + LL
Sbjct: 220 EVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSF--PSNVDISAEAKDLISSLL 277
Query: 415 EVDPAKRYTSEQLLQDPWLNS 435
DP+ R + + ++ + ++
Sbjct: 278 THDPSIRPSIDDIVDHEFFHT 298
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 113 bits (282), Expect = 8e-25
Identities = 85/322 (26%), Positives = 143/322 (44%), Gaps = 71/322 (22%)
Query: 116 ELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKK 175
++ ++ + + IG+GAF V RG Q +VAIK++ + ++
Sbjct: 20 KIGNFVIKETIGKGAFGAVKRGTH-------------IQTGYDVAIKILNRGRMKGLGTV 66
Query: 176 GDEKNGKTSTAEQVLKEIA-IHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEI 234
+N + + I + +++S+ +I +++ EL++GGE+F I
Sbjct: 67 NKTRNEIDNLQKLTHPHITRLFRVISTPSDI-------------FLVMELVSGGELFSYI 113
Query: 235 VKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDD 294
+ SR +Q+ + V Y H IVHRD+KPENLL +
Sbjct: 114 TRKGALPIRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLD----------------- 156
Query: 295 PSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN---TKTPCGTVGYTAPEVVKDER 351
+K+ADFGLS Y T+ T CG+ Y APE++ ++
Sbjct: 157 -----------------ANKNIKIADFGLSN--YMTDGDLLSTACGSPNYAAPELISNKL 197
Query: 352 Y-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCV 410
Y +VD+W G +LY +LCG PF D+ + L KI G YT P+ + A + +
Sbjct: 198 YVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTV--PY--SMEKQAADLI 253
Query: 411 RKLLEVDPAKRYTSEQLLQDPW 432
+L+VDP KR ++++ W
Sbjct: 254 STMLQVDPVKRADVKRIVNHSW 275
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 113 bits (282), Expect = 8e-25
Identities = 79/283 (27%), Positives = 133/283 (46%), Gaps = 53/283 (18%)
Query: 158 EVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKY 217
+VA+KV+ K +L + +K + +E+ K+V N+V + +++
Sbjct: 45 KVAVKVVDKTKLDDVSKA------------HLFQEVRCMKLVQH-PNVVRLYEVIDTQTK 91
Query: 218 YYIIQELLAGGEIFGEIVKY-TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLF 276
Y++ EL GG+++ I+K+ + SE+L+R RQ+ A+ Y HQL +VHRD+KPEN++F
Sbjct: 92 LYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDLKPENVVF 151
Query: 277 EPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLS-KQIYQTNTKTP 335
+VKL DFG S K + +T
Sbjct: 152 ---------------------------------FEKLGLVKLTDFGFSNKFLPGQKLETF 178
Query: 336 CGTVGYTAPEVVKDERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTF 394
CG++ Y+APE++ + Y + VD+W +G +LY ++CG PF I +YT
Sbjct: 179 CGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFEKANDSETLTMIMDCKYTV 238
Query: 395 LRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYD 437
+S ++ + +L DP KR T E++ WL D
Sbjct: 239 P----SHVSTDCRDLIASMLVRDPKKRATVEEIASSAWLKPID 277
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 112 bits (281), Expect = 1e-24
Identities = 88/337 (26%), Positives = 146/337 (43%), Gaps = 71/337 (21%)
Query: 109 DVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKE---VAIKVII 165
D+ + D+ + + +G+G F VY +A++ K VA+KV+
Sbjct: 66 DILTRHFTIDDFEIGRPLGKGKFGNVY----------------LAREKKSHFIVALKVLF 109
Query: 166 KQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELL 225
K Q+ EK G Q+ +EI I + NI+ ++ + Y+I E
Sbjct: 110 KSQI--------EKEG---VEHQLRREIEIQAHLHH-PNILRLYNYFYDRRRIYLILEYA 157
Query: 226 AGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNP 285
GE++ E+ K F E + ++ +LA+A+ Y H ++HRDIKPENLL
Sbjct: 158 PRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLL--------- 208
Query: 286 KPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPE 345
+K+ADFG S KT CGT+ Y PE
Sbjct: 209 -------------------------GLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPE 243
Query: 346 VVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDG 405
+++ ++ +VD+W +G + Y +L G PPF + +I + + F + G
Sbjct: 244 MIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPA----SVPTG 299
Query: 406 AKNCVRKLLEVDPAKRYTSEQLLQDPWL--NSYDCLP 440
A++ + KLL +P++R Q+ PW+ NS LP
Sbjct: 300 AQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLP 336
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 112 bits (281), Expect = 1e-24
Identities = 95/319 (29%), Positives = 150/319 (46%), Gaps = 66/319 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + IG+G F+ V A++++ + +VAIK+I K L +E
Sbjct: 41 YELEKTIGKGNFAVVKL-----------ATNIVTKT--KVAIKIIDKTCL------NEEY 81
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
KT +EIAI K + +I + ES+ Y++ E GEIF +V
Sbjct: 82 LNKT------FREIAILKSLRH-PHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGR 134
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
E + V QL +AV Y H+ G+VHRD+K EN+L L
Sbjct: 135 MKEPEAARVFTQLVSAVHYCHRRGVVHRDLKAENVL-----------------------L 171
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYS-MQVD 357
D+ + +KLADFG S + T KT CG+ Y APEV + Y + D
Sbjct: 172 DKDMN-----------IKLADFGFSNHYEEGATLKTWCGSPPYAAPEVFQGLEYDGPKSD 220
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W +G VLY ++CG PF + I L ++ G++ P++ +S + +R +L V+
Sbjct: 221 IWSLGVVLYALVCGALPFDGKTILELKSRVVLGKFRI--PFF--MSQECEQLIRNMLVVE 276
Query: 418 PAKRYTSEQLLQDPWLNSY 436
P +RYT +Q+++ WL+ +
Sbjct: 277 PDRRYTIKQIIKHRWLSEW 295
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 112 bits (280), Expect = 1e-24
Identities = 84/321 (26%), Positives = 144/321 (44%), Gaps = 65/321 (20%)
Query: 114 QTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTN 173
+ ++ Y L +G G F KV G + +VA+K++ +Q++ + +
Sbjct: 10 RVKIGHYVLGDTLGVGTFGKVKIGEHQLTG-------------HKVAVKILNRQKIRSLD 56
Query: 174 KKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGE 233
G ++ +EI K+ +I+ + ++++ E ++GGE+F
Sbjct: 57 VVG-----------KIKREIQNLKLFRH-PHIIKLYQVISTPTDFFMVMEYVSGGELFDY 104
Query: 234 IVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSD 293
I K+ E +R + +Q+ +AV Y H+ +VHRD+KPEN+L +
Sbjct: 105 ICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD---------------- 148
Query: 294 DPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPEVVKDERY 352
K+ADFGLS + +T CG+ YTAPEV+ Y
Sbjct: 149 ------------------AHMNAKIADFGLSNMMSDGEFLRTSCGSPNYTAPEVISGRLY 190
Query: 353 S-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVR 411
+ +VD+W G +LY +LCG PF DE + L +KI G F P + ++ +
Sbjct: 191 AGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG--VFYIP--EYLNRSVATLLM 246
Query: 412 KLLEVDPAKRYTSEQLLQDPW 432
+L+VDP KR T + + + W
Sbjct: 247 HMLQVDPLKRATIKDIREHEW 267
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 112 bits (280), Expect = 1e-24
Identities = 77/286 (26%), Positives = 133/286 (45%), Gaps = 49/286 (17%)
Query: 146 NGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENI 205
N ASS ++ + + + + L + G K ++V+K + I++ + I
Sbjct: 37 NTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNE-KRI 95
Query: 206 VSFIDFQ---------ESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAV 256
+ IDF + Y Y++ E + GGE+F + + FSE + Q+ AV
Sbjct: 96 LQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAV 155
Query: 257 KYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVV 316
+Y+H L ++HRD+KPENLL + ++
Sbjct: 156 QYLHSLDLIHRDLKPENLLIDQQGYL---------------------------------- 181
Query: 317 KLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFF 376
++ DFG +K++ + T T CGT Y APE++ + Y+ VD W +G ++Y + GFPPF+
Sbjct: 182 QVTDFGFAKRV-KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY 240
Query: 377 DEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRY 422
++ + EKI G F ++S K+ +R LL+VD KR+
Sbjct: 241 ADQPIQIYEKIVSGRVRFP----SKLSSDLKHLLRSLLQVDLTKRF 282
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 112 bits (280), Expect = 1e-24
Identities = 86/319 (26%), Positives = 140/319 (42%), Gaps = 45/319 (14%)
Query: 118 KDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGD 177
K Y + IG+G FS V+ T +G + +Y+ ++ P+ +
Sbjct: 55 KQYEIGAIIGKGNFSSVHL----TRRKEDGTKCALKVRYQST-----LQFSFPSKFFQQV 105
Query: 178 EKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKY 237
EK V E+ + ++ ++I+S ID +E Y+I+ E G+++ I K
Sbjct: 106 EKRAMRGKCFFVDNEVEMLSLIQH-DHIISIIDAFSTENQYFIVFEHAQYGDLYETIRKN 164
Query: 238 TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPST 297
E + + Q+A+A+ Y+H+ +VHRD+KPENLL
Sbjct: 165 GRIEEPDAAIITLQVASALNYLHERNVVHRDVKPENLLL--------------------- 203
Query: 298 KLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVD 357
VKL DFGL+ I + CGT Y APEV+++ YS + D
Sbjct: 204 -------------VDKFSVKLCDFGLACHILGPLYRI-CGTPTYCAPEVLRETGYSTRCD 249
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W +G VLY +L G+ PF L + I + + P W IS AK+ V +L+
Sbjct: 250 IWSLGVVLYVMLVGYAPFRAPDQTRLFKLIMQAKPNLDMPEWKGISLKAKDLVSRLMNKT 309
Query: 418 PAKRYTSEQLLQDPWLNSY 436
+R + Q++ PW+ Y
Sbjct: 310 EERRPLASQIMAHPWIAPY 328
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 112 bits (280), Expect = 1e-24
Identities = 102/362 (28%), Positives = 167/362 (45%), Gaps = 74/362 (20%)
Query: 77 VQIVQGKDGTSQEENTYDESSDATTTPQEEPEDVFPEQTELKD-YTLIQKIGEGAFSKVY 135
+Q + G +NT E T+TP+ P+ + L D Y + + +G G+F+KVY
Sbjct: 17 IQFMAGLLARIVTKNTNKE----TSTPESPRSPRTPQGSILMDKYEIGKLLGHGSFAKVY 72
Query: 136 RGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAI 195
N +G ++VAIKVI K EK K+ A + +EI+I
Sbjct: 73 LA----RNIHSG---------EDVAIKVIDK-----------EKIVKSGLAGHIKREISI 108
Query: 196 HKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANA 255
+ V IV ++ ++ YI+ E + GGE++ + + E +R +QL ++
Sbjct: 109 LRRVRH-PYIVHLLEVMATKTKIYIVMEYVRGGELYNTVARGR-LREGTARRYFQQLISS 166
Query: 256 VKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXV 315
V + H G+ HRD+K ENLL + D+G
Sbjct: 167 VAFCHSRGVYHRDLKLENLLLD----------------------DKGN------------ 192
Query: 316 VKLADFGLS---KQIYQTNT-KTPCGTVGYTAPEVVKDERYS-MQVDMWGVGCVLYTVLC 370
VK++DFGLS +Q+ Q +T CGT Y APEV+ + Y + D+W G +L+ ++
Sbjct: 193 VKVSDFGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKGYEGAKADIWSCGVILFVLMA 252
Query: 371 GFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQD 430
G+ PF D+ I V+ KI +G+ F P W S V ++L+ +P R T ++++
Sbjct: 253 GYLPFDDKNILVMYTKIYKGQ--FKCPKW--FSPELARLVTRMLDTNPDTRITIPEIMKH 308
Query: 431 PW 432
W
Sbjct: 309 RW 310
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 112 bits (279), Expect = 2e-24
Identities = 87/284 (30%), Positives = 131/284 (45%), Gaps = 44/284 (15%)
Query: 160 AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYY 219
A+KVI K N G+ N + + +EI I K++S N++S D E+ Y
Sbjct: 48 AVKVISKSIF---NNNGNHSNDDSVLPYNIEREIVIMKLLSH-PNVLSLYDVWETNNNLY 103
Query: 220 IIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPI 279
+I E GE+F +V + E + + RQ+ + Y H LGIVHRD+KPENLL +
Sbjct: 104 LILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLL---L 160
Query: 280 DFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSK-QIYQTNTKTPCGT 338
D N +K+ADFG++ Q +T CG+
Sbjct: 161 DSFYN-------------------------------IKIADFGMAALQTDADLLETSCGS 189
Query: 339 VGYTAPEVVKDERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDV--LTEKISRGEYTFL 395
Y APE+V Y D+W G +L+ +L G PF +E +V L K+ +G+ F
Sbjct: 190 PHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQ--FE 247
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCL 439
P +IS A++ + K+L VDP +R +L P L Y +
Sbjct: 248 MPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTI 291
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 112 bits (279), Expect = 2e-24
Identities = 90/373 (24%), Positives = 158/373 (42%), Gaps = 77/373 (20%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
DY L +IG G+F+ V+ +S EVA+K I K+ L
Sbjct: 9 DYALGPRIGSGSFAVVWLAKHRSSGL-------------EVAVKEIDKKLL--------- 46
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
+ +LKEI+I + NI+ F + E+ +++ E +GG++ G I ++
Sbjct: 47 ---SPKVRDNLLKEISILSTIDH-PNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRHG 102
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
E +++H +RQLA ++ + + +HRD+KP+NLL + P
Sbjct: 103 KVPEAVAKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLSSKEVTP--------------- 147
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIY-QTNTKTPCGTVGYTAPEVVKDERYSMQVD 357
++K+ DFG ++ + ++ +T CG+ Y APE++++++Y + D
Sbjct: 148 ----------------LLKIGDFGFARSLTPESMAETFCGSPLYMAPEIIRNQKYDAKAD 191
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRG-EYTFLRPWWDQISDGAKNCVRKLLEV 416
+W G +L+ ++ G PPF L I R E F ++I + R LL
Sbjct: 192 LWSAGAILFQLVTGKPPFDGNNHIQLFHNIVRDTELKFPEDTRNEIHPDCVDLCRSLLRR 251
Query: 417 DPAKRYTSEQLLQDPWLNSYDCLPSADHSN-------------APSTGEKRRHS-----H 458
+P +R T + +L +P +HS PST R S H
Sbjct: 252 NPIERLTFREFFNHMFLREPRQIPDVEHSGFSTCTGKSLLPSAQPSTSTNRFKSSAENVH 311
Query: 459 KHSRKAYKKNASL 471
KH + N+ +
Sbjct: 312 KHGSSSSASNSQI 324
>HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 111 bits (278), Expect = 2e-24
Identities = 85/340 (25%), Positives = 154/340 (45%), Gaps = 67/340 (19%)
Query: 99 ATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKE 158
A P +E +V + + Y + +G+G F+K + + KE
Sbjct: 32 AAAPPAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFE--------------ISDADTKE 77
Query: 159 V-AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKY 217
V A K++ K L +++ E++ EI+IH+ ++ +++V F F E +
Sbjct: 78 VFAGKIVPKSLLLKPHQR-----------EKMSMEISIHRSLAH-QHVVGFHGFFEDNDF 125
Query: 218 YYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFE 277
+++ EL + + +E +R+ +RQ+ +Y+H+ ++HRD+K NL
Sbjct: 126 VFVVLELCRRRSLLEPHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLF-- 183
Query: 278 PIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT--KTP 335
L+E + VK+ DFGL+ ++ KT
Sbjct: 184 ---------------------LNEDL-----------EVKIGDFGLATKVEYDGERKKTL 211
Query: 336 CGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFL 395
CGT Y APEV+ + +S +VD+W +GC++YT+L G PPF + +I + EY+
Sbjct: 212 CGTPNYIAPEVLSKKEHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIP 271
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNS 435
+ I+ A + ++K+L+ DP R T +LL D + S
Sbjct: 272 K----HINPVAASLIQKMLQTDPTARPTINELLNDEFFTS 307
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 111 bits (278), Expect = 2e-24
Identities = 90/342 (26%), Positives = 148/342 (42%), Gaps = 72/342 (21%)
Query: 95 ESSDATTTPQEEPEDVFPEQT-ELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIA 153
E + T PQ+ P++T EL ++ + + +G G F VY S
Sbjct: 134 EKTKTETQPQK------PKKTWELNNFDIGRLLGRGKFGNVYLAREKESQFV-------- 179
Query: 154 QQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQE 213
VA+KV+ K+Q+ G+++ QV +EI I + + + F +
Sbjct: 180 -----VALKVLFKRQI-----------GESNVEHQVRREIEIQSHLRHPHILRLYAYFHD 223
Query: 214 SEKYYYIIQELLAGGEIFGEIVKYTY--FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKP 271
+ Y I+ E G +F + F E S I+ L +A+ Y+H+ I+HRDIKP
Sbjct: 224 DVRIYLIL-EYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKP 282
Query: 272 ENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN 331
ENLL V+K+ADFG S +
Sbjct: 283 ENLLL----------------------------------GHKGVLKIADFGWSVHEPNSM 308
Query: 332 TKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGE 391
T CGTV Y PE+V+ + ++ VD+W +G + + +L G PF+ + D +KI + +
Sbjct: 309 RMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETYKKILKVD 368
Query: 392 YTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
Y + IS A + + KLL ++P R +Q++ PW+
Sbjct: 369 YKLP----EHISKAASHLISKLLVLNPQHRLPLDQVMVHPWI 406
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 111 bits (277), Expect = 3e-24
Identities = 92/371 (24%), Positives = 165/371 (43%), Gaps = 84/371 (22%)
Query: 77 VQIVQGKDGTSQEENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYR 136
V +V+ +G S +EN DE S T E+ + ++D+ +++ +G+GAF KVY+
Sbjct: 99 VDLVECVEGESIKEN--DEFSGNDDTDSEKSPEEVSGVVGIEDFEVLKVVGQGAFGKVYQ 156
Query: 137 GIPSTSNCSNGASSVIAQQYKEV-AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAI 195
V + E+ A+KV+ K ++ N + + AE+ +
Sbjct: 157 --------------VRKKDTSEIYAMKVMRKDKIVEKN------HAEYMKAERDILTKID 196
Query: 196 HKIVSSGENIVSFIDFQESEKY-YYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLAN 254
H + + + KY Y++ + + GG +F ++ F EDL+R ++ +
Sbjct: 197 HPFIVQ-------LKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVS 249
Query: 255 AVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXX 314
AV ++H+ GI+HRD+KPEN+L +
Sbjct: 250 AVSHLHEKGIMHRDLKPENILMD----------------------------------VDG 275
Query: 315 VVKLADFGLSKQIYQ-TNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFP 373
V L DFGL+K+ + T + + CGT Y APE+V+ + + D W VG +LY +L G P
Sbjct: 276 HVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKP 335
Query: 374 PFFDEK----IDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTS----- 424
PF K ++ +KI ++ +S+ A ++ LL+ +P +R S
Sbjct: 336 PFLGSKGKIQQKIVKDKIKLPQF---------LSNEAHALLKGLLQKEPERRLGSGPSGA 386
Query: 425 EQLLQDPWLNS 435
E++ + W +
Sbjct: 387 EEIKKHKWFKA 397
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 595
Score = 111 bits (277), Expect = 3e-24
Identities = 83/275 (30%), Positives = 125/275 (45%), Gaps = 47/275 (17%)
Query: 174 KKGDEKN----------GKTSTA---EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYI 220
KKGD K+ K +TA E V +E+ + K +S + ++ + D E YI
Sbjct: 163 KKGDIKDHPIAVKIISKAKMTTAIAIEDVRREVKLLKSLSGHKYLIKYYDACEDANNVYI 222
Query: 221 IQELLAGGEIFGEIV-KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPI 279
+ EL GGE+ I+ + + ED ++ ++ Q+ V + H G+VHRD+KPEN LF
Sbjct: 223 VMELCDGGELLDRILARGGKYPEDDAKAIVVQILTVVSFCHLQGVVHRDLKPENFLF--- 279
Query: 280 DFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIY-QTNTKTPCGT 338
SS + S +KL DFGLS I G+
Sbjct: 280 ----------TSSREDSD------------------LKLIDFGLSDFIRPDERLNDIVGS 311
Query: 339 VGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPW 398
Y APEV+ YS++ D+W +G + Y +LCG PF+ + + R E +
Sbjct: 312 AYYVAPEVL-HRSYSLEADIWSIGVITYILLCGSRPFWARTESGIFRTVLRTEPNYDDVP 370
Query: 399 WDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
W S K+ V++LL D KR ++ Q L PWL
Sbjct: 371 WPSCSSEGKDFVKRLLNKDYRKRMSAVQALTHPWL 405
>At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 284
Score = 111 bits (277), Expect = 3e-24
Identities = 73/238 (30%), Positives = 115/238 (47%), Gaps = 35/238 (14%)
Query: 198 IVSSGENIVSFIDFQESEKYYYIIQELLAGG-EIFGEIVKYTYFSEDLSRHVIRQLANAV 256
++S NIV D +++ I EL+ I+ +V F E + +Q+ A+
Sbjct: 69 LLSYHPNIVQIHDLIDTDSTLSIFMELVHPSVSIYDRLVSSGTFFEPQTASFAKQILQAL 128
Query: 257 KYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVV 316
+ H+ G+VHRDIKPEN+L + LR+ V
Sbjct: 129 SHCHRYGVVHRDIKPENILVD-----------LRND----------------------TV 155
Query: 317 KLADFGLSKQIYQ-TNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPF 375
K+ DFG + + T+ GT Y APEV+ Y +VD+W G VLYT+L G PPF
Sbjct: 156 KICDFGSGIWLGEGETTEGVVGTPYYVAPEVLMGYSYGEKVDLWSAGVVLYTMLAGTPPF 215
Query: 376 FDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
+ E + + E + RG F + +S AK+ +RKL+ D ++R+++EQ L+ PW+
Sbjct: 216 YGETAEEIFEAVLRGNLRFPTKIFRGVSSMAKDFLRKLICKDASRRFSAEQALRHPWI 273
>CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 416
Score = 111 bits (277), Expect = 3e-24
Identities = 75/250 (30%), Positives = 114/250 (45%), Gaps = 33/250 (13%)
Query: 185 TAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDL 244
T + + +E+ + + + N+V E+ I+ EL++GGE+F + E
Sbjct: 115 TRQNIEREVRVLQKIRGNSNVVELHAVYETASDVIIVLELVSGGELFDHVCAKECLDEVE 174
Query: 245 SRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVF 304
+ I+Q+ AV+++H L IVH DIKPEN++ L+ D
Sbjct: 175 AAAFIKQILLAVRHLHSLHIVHLDIKPENVM-------------LKQRGDSQ-------- 213
Query: 305 RPXXXXXXXXVVKLADFGLSKQIYQ-TNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGC 363
+K+ DFGLS++I K GT + APEVV E S DMW VG
Sbjct: 214 -----------IKIIDFGLSREIEPGAVVKDMVGTPEFVAPEVVNYEALSPATDMWAVGV 262
Query: 364 VLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYT 423
V Y +L G PF + D I+R Y F ++ S AK+ + +L D +R T
Sbjct: 263 VTYILLSGGSPFLGDNRDETFSNITRVRYHFSDRYFKNTSKHAKDFIYRLFVRDVDQRAT 322
Query: 424 SEQLLQDPWL 433
E+ LQ PW+
Sbjct: 323 VEECLQHPWI 332
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 110 bits (276), Expect = 4e-24
Identities = 88/345 (25%), Positives = 144/345 (41%), Gaps = 66/345 (19%)
Query: 79 IVQGKDGTSQEENTYDESSDATTTPQEEPEDVFPEQT--ELKDYTLIQKIGEGAFSKVYR 136
+ Q S +E+ D PE + PE L+D+ + +G G F +V+
Sbjct: 6 LAQAAAAESDSRKVAEETPDGAPALCPSPEALSPEPPVYSLQDFDTLATVGTGTFGRVHL 65
Query: 137 GIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIH 196
T A A + + + +KQ+ N+K VLKE+
Sbjct: 66 VKEKT------AKHFFALKVMSIPDVIRLKQEQHVHNEKS------------VLKEV--- 104
Query: 197 KIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAV 256
S ++ E++ Y++ E + GGE+F + FS ++ A+
Sbjct: 105 ----SHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAI 160
Query: 257 KYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVV 316
+Y+H IV+RD+KPEN+L + I
Sbjct: 161 EYLHSKEIVYRDLKPENILLDRDGHI---------------------------------- 186
Query: 317 KLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFF 376
KL DFG +K++ T T CGT Y APEV++ + + VD W +G +++ +L GFPPFF
Sbjct: 187 KLTDFGFAKKLVD-RTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFF 245
Query: 377 DEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKR 421
D+ + +KI G+ F R + K+ ++KLL VD +R
Sbjct: 246 DDNPFGIYQKILAGKIDFPR----HLDFHVKDLIKKLLVVDRTRR 286
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 110 bits (276), Expect = 4e-24
Identities = 89/347 (25%), Positives = 148/347 (42%), Gaps = 69/347 (19%)
Query: 87 SQEENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSN 146
++ ++ E+SDA+ ++ + L D+ + + +G G F VY SN
Sbjct: 5 TETQHQEKEASDASAAAAQK-------RWTLSDFDIGKPLGRGKFGHVYLAREKRSN--- 54
Query: 147 GASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIV 206
VA+KV+ K QL ++ Q+ +E+ I + NI+
Sbjct: 55 ----------HVVALKVLFKSQLQ-----------QSQVEHQLRREVEIQSHLRH-PNIL 92
Query: 207 SFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVH 266
+ +K Y+I E A GE++ ++ K YFSE + + LA A+ Y H ++H
Sbjct: 93 RLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERRAATYVASLARALIYCHGKHVIH 152
Query: 267 RDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQ 326
RDIKPENLL +K+ADFG S
Sbjct: 153 RDIKPENLLI----------------------------------GAQGELKIADFGWSVH 178
Query: 327 IYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEK 386
+ +T CGT+ Y PE+V+ + VD+W +G + Y L G PPF + +
Sbjct: 179 TF-NRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAMEHSDTYRR 237
Query: 387 ISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
I + + F P IS AK+ + ++L + ++R +LL+ PW+
Sbjct: 238 IVQVDLKF--PPKPIISASAKDLISQMLVKESSQRLPLHKLLEHPWI 282
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 110 bits (275), Expect = 5e-24
Identities = 87/334 (26%), Positives = 150/334 (44%), Gaps = 72/334 (21%)
Query: 116 ELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKK 175
+++D+ + +G+G+F+ VYR S EVAIK+I K+ +
Sbjct: 8 KIEDFKVGNLLGKGSFAGVYRAESIHSGL-------------EVAIKMIDKKAMY----- 49
Query: 176 GDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV 235
K ++V E+ IH + +I+ ++ E Y Y++ E+ GE+ +
Sbjct: 50 ------KAGMVQRVQNEVKIHCQLKH-PSILELYNYFEDSNYVYLVLEMCHNGEMNRYLK 102
Query: 236 -KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDD 294
+ FSE+ +RH + Q+ + Y+H GI+HRD+ NLL R+ +
Sbjct: 103 NRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLT------------RNMN- 149
Query: 295 PSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK--TPCGTVGYTAPEVVKDERY 352
+K+ADFGL+ Q+ + K T CGT Y +PE+ +
Sbjct: 150 ---------------------IKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAH 188
Query: 353 SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEY---TFLRPWWDQISDGAKNC 409
++ D+W +GC+ YT+L G PPF + + K+ +Y TFL S AK+
Sbjct: 189 GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFL-------SIEAKDL 241
Query: 410 VRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSAD 443
+ +LL +PA R + +L P+++ S D
Sbjct: 242 IHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKD 275
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 110 bits (275), Expect = 5e-24
Identities = 91/345 (26%), Positives = 158/345 (45%), Gaps = 62/345 (17%)
Query: 94 DESSDATTTPQEE-PEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVI 152
+E TP E+ +D+ ++ +++ TL ++IG F ++ RG + N S +
Sbjct: 38 EEGQPRQLTPFEKLTQDMSQDEKVVREITLGKRIG---FYRI-RGEIGSGNFSQVKLGIH 93
Query: 153 AQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQ 212
+ ++VAIK++ K +L D+K + + E E H NI+ +
Sbjct: 94 SLTKEKVAIKILDKTKL-------DQKTQRLLSREISSMEKLHHP------NIIRLYEVV 140
Query: 213 ESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPE 272
E+ +++ E GGE+FG+I SE S+ + Q+ +AVK+MH+ I+HRD+K E
Sbjct: 141 ETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAE 200
Query: 273 NLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFG---LSKQIYQ 329
N+ + VK+ DFG +SK+
Sbjct: 201 NVFY----------------------------------TSNTCVKVGDFGFSTVSKKGEM 226
Query: 330 TNTKTPCGTVGYTAPEVVKDERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKIS 388
NT CG+ Y APE+ +DE Y + VD+W +G +LY ++ G PF E + L + I
Sbjct: 227 LNTF--CGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSIL 284
Query: 389 RGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
G Y+ +S+ +R +L+ P +RY + ++ D W+
Sbjct: 285 EGTYSVP----PHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM 325
>Hs16507245 [T] KOG0583 Serine/threonine protein kinase
Length = 358
Score = 110 bits (275), Expect = 5e-24
Identities = 94/337 (27%), Positives = 153/337 (44%), Gaps = 71/337 (21%)
Query: 118 KDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYK-EVAIKVIIKQQLPNTNKKG 176
K Y + +G+G+++KV S +++ K VA+K+I
Sbjct: 10 KGYIVGINLGKGSYAKV--------------KSAYSERLKFNVAVKII------------ 43
Query: 177 DEKNGKTSTAEQVL-KEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV 235
D K T E+ L +E+ I V+ G I ++ F+ S+ YII EL G++ I
Sbjct: 44 DRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIK 103
Query: 236 KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDP 295
ED++R + RQL++AVKY H L IVHRD+K ENLL + DF
Sbjct: 104 CQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDK-DF-------------- 148
Query: 296 STKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN------TKTPCGTVGYTAPEVVKD 349
+KL+DFG SK+ + + +KT CG+ Y APEV++
Sbjct: 149 -------------------NIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQS 189
Query: 350 ERYSMQV-DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKN 408
Y +V D+W +G +LY ++CG P+ D I + F P ++ K+
Sbjct: 190 IPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDF--PRSKNLTCECKD 247
Query: 409 CVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHS 445
+ ++L+ D ++R +++L WL P++ S
Sbjct: 248 LIYRMLQPDVSQRLHIDEILSHSWLQPPKPKPTSSAS 284
>CE06635 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7160
Score = 110 bits (275), Expect = 5e-24
Identities = 112/429 (26%), Positives = 178/429 (41%), Gaps = 78/429 (18%)
Query: 78 QIVQGKDGTSQEENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRG 137
+IV+GK S + Y PQ P ++ + L Y + +++G GAF V+R
Sbjct: 6224 KIVRGKGTVSSNYDNYVFDIWKQYYPQ--PVEIKHDHV-LDHYDIHEELGTGAFGVVHR- 6279
Query: 138 IPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHK 197
+ + +N A+ + ++ S E V KEI
Sbjct: 6280 VTERATGNNFAAKFVMTPHE--------------------------SDKETVRKEIQTMS 6313
Query: 198 IVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV-KYTYFSEDLSRHVIRQLANAV 256
++ +V+ D E + +I E ++GGE+F ++ ++ SED + +RQ+ +
Sbjct: 6314 VLRH-PTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAVEYMRQVCKGL 6372
Query: 257 KYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVV 316
+MH+ VH D+KPEN++F RS++ +
Sbjct: 6373 CHMHENNYVHLDLKPENIMFTT----------KRSNE----------------------L 6400
Query: 317 KLADFGLSKQIY-QTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPF 375
KL DFGL+ + + + K GT + APEV + + DMW VG + Y +L G PF
Sbjct: 6401 KLIDFGLTAHLDPKQSVKVTTGTAEFAAPEVAEGKPVGYYTDMWSVGVLSYILLSGLSPF 6460
Query: 376 FDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNS 435
E D + ++ + IS+ K+ +RKLL DP R T Q L+ PWL
Sbjct: 6461 GGENDDETLRNVKSCDWNMDDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALEHPWLTP 6520
Query: 436 YDCLPSADHSNAPSTGEKRRHSHKHSRKAYKK---------NASLL--YSPAAVAMRDAF 484
+ P D S K R S K A+ + N S L + P ++RDAF
Sbjct: 6521 GNA-PGRDSQIPSSRYTKIRDSIKTKYDAWPEPLPPLGRISNYSSLRKHRPQEYSIRDAF 6579
Query: 485 -DVSNAVQR 492
D S A R
Sbjct: 6580 WDRSEAQPR 6588
>CE06634 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 6831
Score = 110 bits (275), Expect = 5e-24
Identities = 112/429 (26%), Positives = 178/429 (41%), Gaps = 78/429 (18%)
Query: 78 QIVQGKDGTSQEENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRG 137
+IV+GK S + Y PQ P ++ + L Y + +++G GAF V+R
Sbjct: 5895 KIVRGKGTVSSNYDNYVFDIWKQYYPQ--PVEIKHDHV-LDHYDIHEELGTGAFGVVHR- 5950
Query: 138 IPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHK 197
+ + +N A+ + ++ S E V KEI
Sbjct: 5951 VTERATGNNFAAKFVMTPHE--------------------------SDKETVRKEIQTMS 5984
Query: 198 IVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV-KYTYFSEDLSRHVIRQLANAV 256
++ +V+ D E + +I E ++GGE+F ++ ++ SED + +RQ+ +
Sbjct: 5985 VLRH-PTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAVEYMRQVCKGL 6043
Query: 257 KYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVV 316
+MH+ VH D+KPEN++F RS++ +
Sbjct: 6044 CHMHENNYVHLDLKPENIMFTT----------KRSNE----------------------L 6071
Query: 317 KLADFGLSKQIY-QTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPF 375
KL DFGL+ + + + K GT + APEV + + DMW VG + Y +L G PF
Sbjct: 6072 KLIDFGLTAHLDPKQSVKVTTGTAEFAAPEVAEGKPVGYYTDMWSVGVLSYILLSGLSPF 6131
Query: 376 FDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNS 435
E D + ++ + IS+ K+ +RKLL DP R T Q L+ PWL
Sbjct: 6132 GGENDDETLRNVKSCDWNMDDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALEHPWLTP 6191
Query: 436 YDCLPSADHSNAPSTGEKRRHSHKHSRKAYKK---------NASLL--YSPAAVAMRDAF 484
+ P D S K R S K A+ + N S L + P ++RDAF
Sbjct: 6192 GNA-PGRDSQIPSSRYTKIRDSIKTKYDAWPEPLPPLGRISNYSSLRKHRPQEYSIRDAF 6250
Query: 485 -DVSNAVQR 492
D S A R
Sbjct: 6251 WDRSEAQPR 6259
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 110 bits (275), Expect = 5e-24
Identities = 90/318 (28%), Positives = 139/318 (43%), Gaps = 69/318 (21%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + +G+G F+KVY G S++ Q VAIK+I K EK
Sbjct: 12 YDVGRLLGQGTFAKVYYG-----------RSILTNQ--SVAIKMIDK-----------EK 47
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
K EQ+ +EI++ +I N+V + ++ Y + E GGE+F ++ K
Sbjct: 48 VMKVGLIEQIKREISVMRIARH-PNVVELYEVMATKTRIYFVMEYCKGGELFNKVAKGK- 105
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
+D++ QL NAV + H + HRDIKPENLL DD
Sbjct: 106 LRDDVAWKYFYQLINAVDFCHSREVYHRDIKPENLLL----------------DDNEN-- 147
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSK----QIYQTNTKTPCGTVGYTAPEVVKDERY-SM 354
+K++DFGLS + T CGT Y APEV+ + Y
Sbjct: 148 ----------------LKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYDGT 191
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+ D+W G VL+ +L G+ PF D + + KI G+ F P W + + + K+L
Sbjct: 192 KADIWSCGVVLFVLLAGYLPFHDSNLMEMYRKI--GKADFKAPSW--FAPEVRRLLCKML 247
Query: 415 EVDPAKRYTSEQLLQDPW 432
+ +P R T ++ + W
Sbjct: 248 DPNPETRITIARIRESSW 265
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 110 bits (274), Expect = 7e-24
Identities = 74/258 (28%), Positives = 128/258 (48%), Gaps = 46/258 (17%)
Query: 186 AEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLS 245
A ++ EI +HK+ + +NI+ F + E+ ++ +++ E GG++F +I ED++
Sbjct: 55 ARRMASEIQLHKLCNGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVA 114
Query: 246 RHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFR 305
+ QL + +MH G+ HRD+KPEN+L +D+ N
Sbjct: 115 QFYFAQLMEGISFMHSKGVAHRDLKPENIL---LDYNGN--------------------- 150
Query: 306 PXXXXXXXXVVKLADFGLSKQI-YQTNTK---TPCGTVGYTAPEVVKDERYSMQVDMWGV 361
+K++DFG + Y+ ++ +P G+ Y APE+ + S +VD+W
Sbjct: 151 ----------LKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEITQQYDGS-KVDVWSC 199
Query: 362 GCVLYTVLCGFPPFFDEKI----DVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
G +L+ +L G P +DE I D L K + E P W+ +S GA + + +L D
Sbjct: 200 GIILFALLLGNTP-WDEAISNTGDYLLYK-KQCERPSYHP-WNLLSPGAYSIITGMLRSD 256
Query: 418 PAKRYTSEQLLQDPWLNS 435
P KRY+ + ++Q PWL S
Sbjct: 257 PFKRYSVKHVVQHPWLTS 274
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 110 bits (274), Expect = 7e-24
Identities = 88/334 (26%), Positives = 152/334 (45%), Gaps = 72/334 (21%)
Query: 116 ELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKK 175
+++D+ + +G+G+F+ VYR A S+ EVAIK+I K+ +
Sbjct: 8 KIEDFKVGNLLGKGSFAGVYR-----------AESI--HTGLEVAIKMIDKKAMY----- 49
Query: 176 GDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV 235
K ++V E+ IH + +I+ ++ E Y Y++ E+ GE+ +
Sbjct: 50 ------KAGMVQRVKNEVKIHCQLKH-PSILELYNYFEDSNYVYLVLEMCHNGEMNRYLK 102
Query: 236 -KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDD 294
+ FSE+ +RH + Q+ + Y+H GI+HRD+ NLL R+ +
Sbjct: 103 NRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLT------------RNMN- 149
Query: 295 PSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK--TPCGTVGYTAPEVVKDERY 352
+K+ADFGL+ Q+ + K T CGT Y +PE+ +
Sbjct: 150 ---------------------IKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAH 188
Query: 353 SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEY---TFLRPWWDQISDGAKNC 409
++ D+W +GC+ YT+L G PPF + + K+ +Y TFL S AK+
Sbjct: 189 GLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFL-------SIEAKDL 241
Query: 410 VRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSAD 443
+ +LL +PA R + +L P+++ S D
Sbjct: 242 IHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKD 275
>Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 110 bits (274), Expect = 7e-24
Identities = 85/340 (25%), Positives = 154/340 (45%), Gaps = 67/340 (19%)
Query: 99 ATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKE 158
A P +E +V + + Y + +G+G F+K + + KE
Sbjct: 32 AAAPPAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFE--------------ISDADTKE 77
Query: 159 V-AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKY 217
V A K++ K L +++ E++ EI+IH+ ++ +++V F F E +
Sbjct: 78 VFAGKIVPKSLLLKPHQR-----------EKMSMEISIHRSLAH-QHVVGFHGFFEDNDF 125
Query: 218 YYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFE 277
+++ EL + + +E +R+ +RQ+ +Y+H+ ++HRD+K NL
Sbjct: 126 VFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLF-- 183
Query: 278 PIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT--KTP 335
L+E + VK+ DFGL+ ++ KT
Sbjct: 184 ---------------------LNEDL-----------EVKIGDFGLATKVEYDGERKKTL 211
Query: 336 CGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFL 395
CGT Y APEV+ + +S +VD+W +GC++YT+L G PPF + +I + EY+
Sbjct: 212 CGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIP 271
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNS 435
+ I+ A + ++K+L+ DP R T +LL D + S
Sbjct: 272 K----HINPVAASLIQKMLQTDPTARPTINELLNDEFFTS 307
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 110 bits (274), Expect = 7e-24
Identities = 97/350 (27%), Positives = 147/350 (41%), Gaps = 87/350 (24%)
Query: 100 TTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEV 159
T+TP P K+Y +++ + +G+F +V+ C + + KEV
Sbjct: 332 TSTPTSRPR---------KEYKVVEHLCKGSFGQVHL-------CELTRNPSVKVAVKEV 375
Query: 160 AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSS--GENIVSFIDFQESEKY 217
A+ K+ K TA Q KE IH+ +S EN++ + E+ K+
Sbjct: 376 AVS---------------GKSRKNLTAVQ--KEYKIHRRLSKIGHENVIQMMKMIETPKF 418
Query: 218 YYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFE 277
Y ++ E GG++F E+ + FS + +QL +K++H+ GIVHRDIK ENLL
Sbjct: 419 YSLVMEYADGGDLFDELKEQEKFSRKDAHSYFKQLIKGLKFIHEQGIVHRDIKLENLLLV 478
Query: 278 PIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLS----KQIYQTNTK 333
+ S DDP T +K+ DFGL+ K +
Sbjct: 479 YSE----------SEDDPGT------------------LKITDFGLATKYRKDGEEIMLS 510
Query: 334 TPCGTVGYTAPEVVKDERY-SMQVDMWGVGCVLYTVLCGFPPF----------FDEKIDV 382
CG+ Y APEV Y VD+W G VL T+L G + + I+
Sbjct: 511 EDCGSKPYAAPEVCTGNDYRGPPVDIWSAGVVLMTMLVGEHSWKVANKEKDAAYSNWINA 570
Query: 383 LTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPW 432
EK + W+ IS +RKLL +P KR T ++ DPW
Sbjct: 571 KDEKAN---------LWNVISGPTTALLRKLLHANPEKRATMAKIEADPW 611
Score = 81.3 bits (199), Expect = 4e-15
Identities = 66/285 (23%), Positives = 121/285 (42%), Gaps = 46/285 (16%)
Query: 187 EQVLKEIAIHKIVSSGE--NIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDL 244
E + +E +I K +S N++ + + + + Y +I GG++F +I ++ D
Sbjct: 61 ESIKRECSIQKRLSKSRHLNMIHLFEIRTNPENYQLILSYADGGDLFEKINQHGGLGSDE 120
Query: 245 SRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVF 304
+ +QL + ++++H+ G+ HRDIKPENLL
Sbjct: 121 AHRYFKQLIDGLRFIHEEGVTHRDIKPENLLL---------------------------- 152
Query: 305 RPXXXXXXXXVVKLADFGLSKQIYQTN-----TKTPCGTVGYTAPEVVKDERY-SMQVDM 358
++K+ADFG + +++ N CG+ Y APEV+ Y VD+
Sbjct: 153 ------TKSGILKIADFGFA-TMHRFNGAEQMLNAYCGSPPYIAPEVLTGIDYRGPAVDI 205
Query: 359 WGVGCVLYTVLCGFPPFFD-EKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
W G VL ++ G P+ + D+ + + W ++S + +RK+L +
Sbjct: 206 WSAGVVLIAMIAGAVPWEQADHFDIFQSRYCSFRRNGRKGAWSRMSQQVISLLRKIL-LQ 264
Query: 418 PAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSR 462
R T + +DPW Y A++ S + R+ S S+
Sbjct: 265 AELRATISMIEEDPWF-IYGEEVDAENKENGSQAQYRQESQTSSK 308
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 110 bits (274), Expect = 7e-24
Identities = 96/340 (28%), Positives = 152/340 (44%), Gaps = 70/340 (20%)
Query: 110 VFPEQTE-LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQ 168
V PE E + + +I+K+G+G + KV GI + +EVAIK I K +
Sbjct: 71 VAPELIESILKFDIIKKLGQGTYGKVQLGINKETG-------------QEVAIKTIKKCK 117
Query: 169 LPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGG 228
+ + ++ +E+ I V NI+ + E+ + ++ E AGG
Sbjct: 118 IE-----------AEADLVRIRREVQIMSSVHH-PNIIHIYEVFENREKMVLVMEFAAGG 165
Query: 229 EIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPK 288
E++ + + +E+ +R + RQ+A AV Y H+ I HRD+K EN+L
Sbjct: 166 ELYDYLSERKVLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENIL------------- 212
Query: 289 LRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIY-QTNTKTPCGTVGYTAPEVV 347
LDE K+ADFGLS Q T CG+ Y +PE+V
Sbjct: 213 ----------LDE-----------KGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIV 251
Query: 348 KDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGA 406
+ Y +VD W +G +LYT++ G PF L ++IS+G+Y + + A
Sbjct: 252 EGTPYQGPEVDCWSLGVLLYTLVYGSMPFDGSNFKRLVKQISQGDY-----YEPRKPSRA 306
Query: 407 KNCVRKLLEVDPAKRYTSEQLLQDPWLNSYD---CLPSAD 443
+R +L V P KR + EQ+ W+N D CL A+
Sbjct: 307 STLIRDMLTVCPRKRASIEQICSHWWVNENDNVSCLDLAE 346
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 110 bits (274), Expect = 7e-24
Identities = 90/327 (27%), Positives = 149/327 (45%), Gaps = 76/327 (23%)
Query: 104 QEEPEDVF---PEQTE-LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEV 159
+EE ED + P T L D+ I+ +G G+F +V + Q+K
Sbjct: 26 KEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRV-----------------MIVQHKPT 68
Query: 160 ----AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESE 215
A+K++ KQ++ + N K ++L+ I +VS + F+++
Sbjct: 69 KDYYAMKILDKQKVVKLKQVEHTLNEK-----RILQAIQFPFLVSLRYH------FKDNS 117
Query: 216 KYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLL 275
Y ++ E + GGE+F + K FSE SR Q+ A +Y+H L +++RD+KPENLL
Sbjct: 118 NLYMVL-EYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLL 176
Query: 276 FEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP 335
+ ++ K+ DFG +K++ + T T
Sbjct: 177 IDSQGYL----------------------------------KVTDFGFAKRV-KGRTWTL 201
Query: 336 CGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFL 395
CGT Y APE++ + Y+ VD W +G ++Y + G+PPFF ++ + EKI G+ F
Sbjct: 202 CGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 261
Query: 396 RPWWDQISDGAKNCVRKLLEVDPAKRY 422
K+ +R LL+VD KRY
Sbjct: 262 ----SHFGSDLKDLLRNLLQVDLTKRY 284
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 109 bits (273), Expect = 9e-24
Identities = 84/305 (27%), Positives = 144/305 (46%), Gaps = 60/305 (19%)
Query: 118 KDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGD 177
+D+ +++ +G+G F +VY+ + A V++ K+V +K K ++ +T
Sbjct: 410 QDFEVLRLLGKGTFGQVYQ-VKKKDTQRIYAMKVLS---KKVIVK---KNEIAHTI---G 459
Query: 178 EKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKY 237
E+N +TA + S IV ++ Y++ + ++GGE+F + K
Sbjct: 460 ERNILVTTASK------------SSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKE 507
Query: 238 TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPST 297
FSED ++ I +L A++++H IV+RD+KPEN+L +
Sbjct: 508 GRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLD-------------------- 547
Query: 298 KLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDER-YSMQV 356
+ L DFGLSK + T T CGT Y APE++ DE Y+ V
Sbjct: 548 --------------ANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTKMV 593
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D W +G +++ + CG+ PFF E + +KI+ G+ F R D +S ++ V+ LL
Sbjct: 594 DFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPR---DVLSQEGRSFVKGLLNR 650
Query: 417 DPAKR 421
+P R
Sbjct: 651 NPKHR 655
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 109 bits (273), Expect = 9e-24
Identities = 94/338 (27%), Positives = 151/338 (43%), Gaps = 73/338 (21%)
Query: 86 TSQEENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCS 145
TSQ +N +E DA+TT + + + D+ ++ +G+G F KV S
Sbjct: 122 TSQIDNIGEEEMDASTTHHK--------RKTMNDFDYLKLLGKGTFGKVILVREKASG-- 171
Query: 146 NGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENI 205
K A+K++ K+ + ++ T T +VLK H ++S +
Sbjct: 172 -----------KYYAMKILKKEVII-----AKDEVAHTLTESRVLKNTR-HPFLTSLK-- 212
Query: 206 VSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIV 265
FQ ++ +++ E + GGE+F + + FSED +R ++ +A+ Y+H IV
Sbjct: 213 ---YSFQTKDRLCFVM-EYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIV 268
Query: 266 HRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSK 325
+RD+K ENL+ + I K+ DFGL K
Sbjct: 269 YRDLKLENLMLDKDGHI----------------------------------KITDFGLCK 294
Query: 326 Q--IYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVL 383
+ KT CGT Y APEV++D Y VD WG+G V+Y ++CG PF+++ + L
Sbjct: 295 EGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKL 354
Query: 384 TEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKR 421
E I + F R +S AK+ + LL DP KR
Sbjct: 355 FELILMEDIKFPR----TLSSDAKSLLSGLLIKDPNKR 388
>CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 391
Score = 109 bits (273), Expect = 9e-24
Identities = 90/346 (26%), Positives = 156/346 (45%), Gaps = 70/346 (20%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y ++ +G+G+FS+V R + ++Y A+KV+ GD
Sbjct: 71 YEVLAVVGKGSFSQVLR-----------VQHRVTRKY--FAVKVV----------NGD-- 105
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
G + +L ++ H V E + F+ S K + I+ ++ +GGE++ +V
Sbjct: 106 CGAVNNELNILSRLS-HPFVIRLEEV-----FKSSSKLF-IVMQMASGGEMYDRVVAKGR 158
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
+SE+ +R+ ++ L + Y+H + + HRD+KPENLL+ + +P+ R
Sbjct: 159 YSEEEARNALKMLLTGLTYLHSIRVTHRDLKPENLLYA------DSRPEAR--------- 203
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN---TKTPCGTVGYTAPEVVKDERYSMQV 356
+ + DFGL+ Q + N T+T CGT Y APE++ Y+ +V
Sbjct: 204 ----------------LLITDFGLAYQATKPNETMTET-CGTPEYIAPELLLRVPYTQKV 246
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
DMW VG + Y ++ G PF D+ L I Y + +W S+ AK V LLE
Sbjct: 247 DMWAVGVIAYILMSGIMPFDDDCRSRLYTHIITANYVYYPQFWSG-SELAKQFVDSLLET 305
Query: 417 DPAKRYTSEQLLQDPWLNSYDCLPSADHSNAPSTGEKRRHSHKHSR 462
+ +R +S ++ WL PS S P+ +S + ++
Sbjct: 306 NSVERLSSSAAMKHEWLTGE--RPSTTQSRPPTRPTSEYNSMQRTK 349
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 109 bits (273), Expect = 9e-24
Identities = 93/327 (28%), Positives = 141/327 (42%), Gaps = 69/327 (21%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + +GEG +KV I + + + AIK+I K + N
Sbjct: 11 YELGRTLGEGNSAKVKFAIDTLTG-------------ESFAIKIIEKSCITRLN------ 51
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
+ Q+ +EI K++ NIV + S+ Y++ E + GG++F IV
Sbjct: 52 -----VSFQIKREIRTLKVLKH-PNIVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGK 105
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
SE R + +QL + V Y H G+ HRD+K EN+L + I
Sbjct: 106 LSETQGRKMFQQLIDGVSYCHNKGVFHRDLKLENVLLDAKGHI----------------- 148
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLS--KQIYQTN--TKTPCGTVGYTAPEVVKDERYSMQ 355
K+ DFGLS Q Y+ + T CG+ Y APEV+ +E Y
Sbjct: 149 -----------------KITDFGLSALSQHYREDGLLHTTCGSPNYVAPEVLANEGYDGA 191
Query: 356 V-DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
D+W G +LY +L G PF D + V+ KI +G+ P W IS GAK ++++L
Sbjct: 192 ASDIWSCGVILYVILTGCLPFDDANLAVICRKIFKGDPPI--PRW--ISLGAKTMIKRML 247
Query: 415 EVDPAKRYTSEQLLQDPWLNSYDCLPS 441
+ +P R T + W +D PS
Sbjct: 248 DPNPVTRVTIAGIKAHDWF-KHDYTPS 273
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 109 bits (272), Expect = 1e-23
Identities = 84/281 (29%), Positives = 130/281 (45%), Gaps = 42/281 (14%)
Query: 183 TSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSE 242
TS +V +E + +++ NI ID + YI+ E + GG++ I+ E
Sbjct: 91 TSQTVRVQREALLGRLLRH-PNICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDE 149
Query: 243 DLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEG 302
DL+R QL NA+ Y+H+ IVHRD+K EN+L
Sbjct: 150 DLARSFAMQLINALVYLHKNFIVHRDLKIENVLL-------------------------- 183
Query: 303 VFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERY-SMQVDMWG 360
VKL DFGLS + + +T CG++ + APE++ + Y +VD+W
Sbjct: 184 -------TQDSRQVKLIDFGLSNFYSKDDLLRTYCGSLYFAAPELLDAKPYIGPEVDVWS 236
Query: 361 VGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAK 420
+G V+Y ++CG PF D + +L KI G+ F IS+ + + +L V+P K
Sbjct: 237 LGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFP----SYISEDCCSLIAAMLNVNPRK 292
Query: 421 RYTSEQLLQDPWL--NSYDCLPSADHSNAPSTGEKRRHSHK 459
R + EQ + PWL NS+ ++ PST R H K
Sbjct: 293 RCSLEQAAKFPWLKKNSFCLYLPIPLTSIPSTPSIRSHVFK 333
>7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 450
Score = 109 bits (272), Expect = 1e-23
Identities = 93/328 (28%), Positives = 144/328 (43%), Gaps = 63/328 (19%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + IG+G FS V R I SN ++ A+K++ + T G
Sbjct: 12 YELCEVIGKGPFSIVRRCIHRESN-------------QQFAVKIVDVAKF--TASPG--- 53
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
STA+ + H + +IV ++ SE Y++ E + G ++ E+V+
Sbjct: 54 ---LSTADLKREATICHML--KHPHIVELLETYSSEGMLYMVFEFMEGSDLCFEVVRRAV 108
Query: 240 ----FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDP 295
+SE ++ H +RQ+ A++Y H+ I+HRD++P L +D N P
Sbjct: 109 AGFVYSEAVACHYMRQILEALRYCHENDILHRDVRPACALLATVD---NSAP-------- 157
Query: 296 STKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVG---YTAPEVVKDER 351
VKL FG + Q+ T T G VG Y APEVV
Sbjct: 158 --------------------VKLGGFGSAIQLPGTRETIETHGRVGCPHYMAPEVVTRRL 197
Query: 352 YSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVR 411
Y D+WG G +L+ +L G PF + L + ++RG +F P W IS AK+ V
Sbjct: 198 YGKGCDVWGAGVMLHVLLSGRLPFLGSGVR-LQQSVARGRLSFEAPEWKSISANAKDLVM 256
Query: 412 KLLEVDPAKRYTSEQLLQDPWLNSYDCL 439
K+L +P R + ++L PW+ D L
Sbjct: 257 KMLAANPHHRLSITEVLDHPWIRDRDKL 284
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 108 bits (271), Expect = 2e-23
Identities = 86/324 (26%), Positives = 139/324 (42%), Gaps = 69/324 (21%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
++D+ L+Q +GEGA+ +V + + + VA+K++
Sbjct: 6 VEDWDLVQTLGEGAYGEVQLAVNRVTE-------------EAVAVKIV------------ 40
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
+ E + KEI I+K+++ EN+V F + Y+ E +GGE+F I
Sbjct: 41 -DMKRAVDCPENIKKEICINKMLNH-ENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEP 98
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
E ++ QL V Y+H +GI HRDIKPENLL + D +
Sbjct: 99 DIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNL-------------- 144
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK----TPCGTVGYTAPEVVKDERY 352
K++DFGL+ N + CGT+ Y APE++K +
Sbjct: 145 --------------------KISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREF 184
Query: 353 SMQ-VDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKIS-RGEYTFLRPWWDQISDGAKNCV 410
+ VD+W G VL +L G P +D+ D E + + T+L P W +I +
Sbjct: 185 HAEPVDVWSCGIVLTAMLAGELP-WDQPSDSCQEYSDWKEKKTYLNP-WKKIDSAPLALL 242
Query: 411 RKLLEVDPAKRYTSEQLLQDPWLN 434
K+L +P+ R T + +D W N
Sbjct: 243 HKILVENPSARITIPDIKKDRWYN 266
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 108 bits (271), Expect = 2e-23
Identities = 85/320 (26%), Positives = 146/320 (45%), Gaps = 66/320 (20%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
++DY + +G+G F+ VY+ + C + +++VAIK+I K+ + T
Sbjct: 11 IEDYEVQHLLGKGGFATVYK-----ARCLH--------THQDVAIKMIDKKLIQGTG--- 54
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
+V +E+ IH + + + FQ++ Y Y++ EL GE+ +
Sbjct: 55 --------LTNRVRQEVEIHSRLKHPSVLQLYTFFQDAN-YVYLVLELAHNGELHRYMNH 105
Query: 237 YTY-FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDP 295
F+E + +++Q+ + Y+H I+HRDI NLL
Sbjct: 106 IARPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLS------------------ 147
Query: 296 STKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK--TPCGTVGYTAPEVVKDERYS 353
VK+ADFGL+ Q+ + + + T CGT Y +PEVV +
Sbjct: 148 ----------------REMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHG 191
Query: 354 MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKL 413
+ D+W VGC+LYT+L G PPF + + K+ EY + P +S A++ + KL
Sbjct: 192 LPADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMSEY--IMP--AHLSYEAQDLINKL 247
Query: 414 LEVDPAKRYTSEQLLQDPWL 433
L+ P +R T E +L P++
Sbjct: 248 LKKLPHERITLEAVLCHPFM 267
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 108 bits (270), Expect = 2e-23
Identities = 74/254 (29%), Positives = 122/254 (47%), Gaps = 44/254 (17%)
Query: 191 KEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIR 250
++I + + IV+ ++ K Y++ + +AGGE+F + K F E+ ++ I
Sbjct: 315 RDILVQTSAADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIA 374
Query: 251 QLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXX 310
+L A++ +H+ GIV+RD+KPEN+L + I
Sbjct: 375 ELLLALQALHKRGIVYRDLKPENILLDVQGHIA--------------------------- 407
Query: 311 XXXXVVKLADFGLSKQIYQ--TNTKTPCGTVGYTAPEVVKDER-YSMQVDMWGVGCVLYT 367
L DFGLSK T T+T CGT Y APEV+ DE Y M VD W +G +LY
Sbjct: 408 -------LCDFGLSKANLSVGTTTRTFCGTTDYLAPEVILDEAGYDMMVDFWSLGVLLYE 460
Query: 368 VLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTS--- 424
+ CG+ PF+ + L + I G+ F R +S A++ ++ LL +P R +
Sbjct: 461 MTCGWSPFYADNTQQLYKNIVFGKVRFPR---GLLSVEARDLIKLLLNRNPKHRLGAHGD 517
Query: 425 -EQLLQDPWLNSYD 437
E++++ P+ + D
Sbjct: 518 VEEVMKHPFFDGID 531
>YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 897
Score = 108 bits (269), Expect = 3e-23
Identities = 92/341 (26%), Positives = 154/341 (44%), Gaps = 62/341 (18%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
+YT ++IG+G+F+ VYRG + + + + VAIK + + +L N
Sbjct: 23 NYTAEKEIGKGSFATVYRG------------HLTSDKSQHVAIKEVSRAKLKNKK----- 65
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
E + EIAI K + +IV ID + + +Y+I E A G++ + +
Sbjct: 66 ------LLENLEIEIAILKKIKH-PHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRK 118
Query: 239 YFSED--LSRHV----------------------IRQLANAVKYMHQLGIVHRDIKPENL 274
E+ L R V ++QLA+A+K++ +VHRDIKP+NL
Sbjct: 119 ELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNL 178
Query: 275 LFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TK 333
L + P S G++ ++K+ADFG ++ + T+ +
Sbjct: 179 L------LSTPLIGYHDSKSFHELGFVGIYN-------LPILKIADFGFARFLPNTSLAE 225
Query: 334 TPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYT 393
T CG+ Y APE++ ++Y+ + D+W VG V++ + CG PPF L +KI R
Sbjct: 226 TLCGSPLYMAPEILNYQKYNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDV 285
Query: 394 FLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLN 434
P + I K + LL DPA+R E+ + +N
Sbjct: 286 ITFPSYCNIEPELKELICSLLTFDPAQRIGFEEFFANKVVN 326
>CE27131_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 360
Score = 108 bits (269), Expect = 3e-23
Identities = 78/258 (30%), Positives = 122/258 (47%), Gaps = 41/258 (15%)
Query: 214 SEKYYYIIQELLAGGEIFGEIVKYT----YFSEDLSRHVIRQLANAVKYMHQLGIVHRDI 269
S Y +II E + G +I EIV+ FSE + H RQL +A+ Y H IVHRD+
Sbjct: 88 SVHYRHIIFENMEGNDICFEIVQRASNGFVFSEYVVSHYTRQLLDALDYCHTRKIVHRDV 147
Query: 270 KPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQ 329
+P NL+ +S D S L KL FG++K + +
Sbjct: 148 RPHNLVL--------------ASKDTSAPL-----------------KLCGFGVAKDLSE 176
Query: 330 TNTKTPCGTVG---YTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEK 386
CG VG + APE+V+ +R S D+W G VL+ +L G PF D+ E+
Sbjct: 177 IGGSMACGRVGVPQFMAPEIVRKDRVSCSSDIWSSGVVLFLLLAGRLPFSGSTSDIY-ER 235
Query: 387 ISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPSADHSN 446
I + + + + IS+ A+N VR++L DP+KR ++++ L W+ + + S H N
Sbjct: 236 IMQTDVD-VDGYMPNISESARNLVRRMLNADPSKRISAKEALNHEWIRDKEHMASRKHMN 294
Query: 447 APSTGEKRRHSHKHSRKA 464
+ RR++ K+
Sbjct: 295 -DVIDQMRRYNESRKLKS 311
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 107 bits (268), Expect = 4e-23
Identities = 86/318 (27%), Positives = 140/318 (43%), Gaps = 69/318 (21%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + +G+G F+KVY G + +N + VAIK+I K +K
Sbjct: 12 YEVGRLLGQGTFAKVYFGRSNHTN-------------ESVAIKMIDK-----------DK 47
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
+ ++Q+ +EI++ +I N+V + ++ Y + E GGE+F ++ K
Sbjct: 48 VMRVGLSQQIKREISVMRIAKH-PNVVELYEVMATKSRIYFVIEYCKGGELFNKVAKGK- 105
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
ED++ QL +AV + H G+ HRDIKPENLL + D +
Sbjct: 106 LKEDVAWKYFYQLISAVDFCHSRGVYHRDIKPENLLLDDNDNL----------------- 148
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSK----QIYQTNTKTPCGTVGYTAPEVVKDERY-SM 354
K++DFGLS + T CGT Y APEV+ + Y
Sbjct: 149 -----------------KVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYEGT 191
Query: 355 QVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
+ D+W G VL+ +L G+ PF D + + KI G+ F P W + K + K+L
Sbjct: 192 KADIWSCGVVLFVLLAGYLPFHDTNLMEMYRKI--GKADFKCPSW--FAPEVKRLLCKML 247
Query: 415 EVDPAKRYTSEQLLQDPW 432
+ + R T ++ + W
Sbjct: 248 DPNHETRITIAKIKESSW 265
>At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 347
Score = 107 bits (268), Expect = 4e-23
Identities = 88/316 (27%), Positives = 142/316 (44%), Gaps = 61/316 (19%)
Query: 118 KDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGD 177
K Y L +++G G F + + ++ K A K I+K +L D
Sbjct: 26 KIYILGEELGRGNFGLTRKCVEKSTG-------------KTFACKTILKTKLK------D 66
Query: 178 EKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKY 237
E+ E V +EI I K +S NIV F + E + +I+ E GGE++ +I+
Sbjct: 67 EE-----CEEDVKREIRIMKQLSGEPNIVEFKNAYEDKDSVHIVMEYCGGGELYDKILAL 121
Query: 238 ----TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSD 293
+SE + +IR + N VK H +G++HRD+KPEN L L S+D
Sbjct: 122 YDVGKSYSEKEAAGIIRSIVNVVKNCHYMGVMHRDLKPENFL-------------LTSND 168
Query: 294 DPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERY 352
D +T VK+ DFG S I + + G+ Y APEV++ Y
Sbjct: 169 DNAT------------------VKVIDFGCSVFIEEGKVYQDLAGSDYYIAPEVLQGN-Y 209
Query: 353 SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRK 412
+ D+W G +LY +LCG PF E + +I E + W A + V++
Sbjct: 210 GKEADIWSAGIILYILLCGKSPFVKEPEGQMFNEIKSLEIDYSEEPWPLRDSRAIHLVKR 269
Query: 413 LLEVDPAKRYTSEQLL 428
+L+ +P +R ++ ++L
Sbjct: 270 MLDRNPKERISAAEVL 285
>CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 370
Score = 107 bits (267), Expect = 5e-23
Identities = 66/213 (30%), Positives = 106/213 (48%), Gaps = 41/213 (19%)
Query: 228 GEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKP 287
GE+F + SE +R +++QL + V+YMH IVHRD+K EN+L
Sbjct: 5 GELFDVLNSTVTVSEKRARRLMKQLFDGVEYMHARDIVHRDLKLENILC----------- 53
Query: 288 KLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQ-TNTKTPCGTVGYTAPEV 346
+DE + ++DFG + +I + + CGT GY APE
Sbjct: 54 -----------IDE------------ERIVISDFGFATRIPRGKKLRDLCGTPGYLAPET 90
Query: 347 VK------DERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWD 400
++ E YS++VD W +G ++YT+L G PF+ K ++ I +G++ F W
Sbjct: 91 IRCQWYDNAEGYSLEVDEWALGVIMYTLLAGCAPFYHRKQLMMLRLIQQGKFEFRNEQWA 150
Query: 401 QISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWL 433
I+ AKN + +LL+VD KR +S++ L W+
Sbjct: 151 NITAEAKNLITQLLQVDATKRISSKECLAHEWM 183
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 107 bits (267), Expect = 5e-23
Identities = 73/250 (29%), Positives = 117/250 (46%), Gaps = 40/250 (16%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSR 246
+++ +E+ IH+ + NIV +F E YI EL A + + +E +R
Sbjct: 81 DKMTQEVQIHRELGH-INIVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEAR 139
Query: 247 HVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRP 306
+ Q+ + V Y+H L I+HRD+K NL +DD
Sbjct: 140 YFTHQIVDGVLYLHDLNIIHRDMKLGNLFL---------------NDD------------ 172
Query: 307 XXXXXXXXVVKLADFGLSKQIY-QTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVL 365
VVK+ DFGL+ + KT CGT Y APEV+ +S +VD+W VGC+L
Sbjct: 173 -------LVVKIGDFGLATTVNGDERKKTLCGTPNYIAPEVLNKAGHSFEVDIWAVGCIL 225
Query: 366 YTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSE 425
Y +L G PPF + ++ +I YT + A + +RK+L+ +P +R T++
Sbjct: 226 YILLFGQPPFESKSLEETYSRIRHNNYTIP----SIATQPAASLIRKMLDPEPTRRPTAK 281
Query: 426 QLLQDPWLNS 435
Q+ +D + S
Sbjct: 282 QVQRDGFFKS 291
>CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 1211
Score = 107 bits (267), Expect = 5e-23
Identities = 81/316 (25%), Positives = 135/316 (42%), Gaps = 62/316 (19%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + +G+G F KVY I + KE A K I K
Sbjct: 45 YQVTKLLGDGKFGKVYCVIEKETG-------------KEFAAKFI--------------K 77
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
K + +V +E++I + + F + +I E++ GGE+F + + +Y
Sbjct: 78 IRKEADRAEVEREVSILTQLRHPRIAQIYDAFYTTTNDVVLIMEIVRGGELFDRVAEESY 137
Query: 240 FSEDLSR-HVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
+L+ +I QL A+ Y+H+ I+H D+KPEN++ +
Sbjct: 138 VLSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIMCVSL------------------- 178
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT-KTPCGTVGYTAPEVVKDERYSMQVD 357
+KL DFGL++ T K GT + APEV+K E+ D
Sbjct: 179 -------------TGNRIKLIDFGLARHYDGTQELKYMAGTPEFAAPEVIKFEKLDYHTD 225
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
MW +G + Y +L G+ PF + + + +G + F +D +++ AK+ V KLL D
Sbjct: 226 MWSIGVITYILLSGYSPFLGDNLGETYCNVEKGVWEFTEE-FDTVTEEAKDFVTKLLVYD 284
Query: 418 PAKRYTSEQLLQDPWL 433
+KR + LQ PW+
Sbjct: 285 QSKRMLPHECLQHPWI 300
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 107 bits (267), Expect = 5e-23
Identities = 87/321 (27%), Positives = 147/321 (45%), Gaps = 71/321 (22%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
++DY +I+ +GEG+F +VY+G + + VA+K I+KQ
Sbjct: 3 VEDYHVIELVGEGSFGRVYKGRRKYTG-------------QTVAMKFIMKQ--------- 40
Query: 177 DEKNGKTSTAEQVLK-EIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIV 235
GKT L+ EI I + + ENI+ +D E+ + + ++ E A GE+F +
Sbjct: 41 ----GKTDKDIHSLRQEIEILRKLKH-ENIIEMLDSFENAREFCVVTEF-AQGELFEILE 94
Query: 236 KYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDP 295
E+ + + +QL A+ Y+H I+HRD+KP+N+L
Sbjct: 95 DDKCLPEEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNILI------------------- 135
Query: 296 STKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT---KTPCGTVGYTAPEVVKDERY 352
VVKL DFG ++ + TNT ++ GT Y APE+VK++ Y
Sbjct: 136 ---------------GAGSVVKLCDFGFARAM-STNTVVLRSIKGTPLYMAPELVKEQPY 179
Query: 353 SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRK 412
VD+W +G +LY + G PPF+ + L I + + D++S ++ ++
Sbjct: 180 DRTVDLWSLGVILYELYVGQPPFYTNSVYALIRHIVKDPVKYP----DEMSTYFESFLKG 235
Query: 413 LLEVDPAKRYTSEQLLQDPWL 433
LL +P R T L + P++
Sbjct: 236 LLNKEPHSRLTWPALREHPFV 256
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 107 bits (266), Expect = 6e-23
Identities = 88/318 (27%), Positives = 143/318 (44%), Gaps = 61/318 (19%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
+KD+ +++G+G++S V S K+ A+KV+ K+ L
Sbjct: 122 IKDFKFGEQLGDGSYSSVVLATARDSG-------------KKYAVKVLSKEYLIR----- 163
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
+K K T E+ +A+ K+ + F FQ+ Y+++ E G+ G I K
Sbjct: 164 -QKKVKYVTVEK----LALQKLNGTKGIFKLFFTFQDEASLYFLL-EYAPHGDFLGLIKK 217
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRS----- 291
Y +E +R+ Q+ +AV +H +GI+HRDIKPEN+L + N K KL
Sbjct: 218 YGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLD-----KNMKVKLTDFGTAK 272
Query: 292 --SDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKD 349
++PS D + F L +K+ GT Y +PE++ D
Sbjct: 273 ILPEEPSNTADGKPY----------------FDL-----YAKSKSFVGTAEYVSPELLND 311
Query: 350 ERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNC 409
+ D+W GC+LY +L G PPF + +K+ + +Y F + QI K+
Sbjct: 312 NYTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAF-TAGFPQI---VKDL 367
Query: 410 VRKLLEVDPAKRYTSEQL 427
V+KLL DP R T +Q+
Sbjct: 368 VKKLLVRDPNDRLTIKQI 385
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 107 bits (266), Expect = 6e-23
Identities = 84/327 (25%), Positives = 153/327 (46%), Gaps = 55/327 (16%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVII--KQQLPNTNK 174
L D+ ++ +G G+ KV +N V A + A K + +Q LP
Sbjct: 117 LGDWEFVETVGAGSMGKVKLAKHRYTN------EVCAVKIVNRATKAFLHKEQMLPPPKN 170
Query: 175 KGDEKNGKTSTAEQVLKEIAIHKIVSSGE-----NIVSFIDFQESEKYYYIIQELLAGGE 229
+ D + +++ ++ + S G+ +I + ++Y++ E ++GG+
Sbjct: 171 EQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQ 230
Query: 230 IFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKL 289
+ I+++ E +R R +A+A+ Y+H IVHRD+K EN++
Sbjct: 231 LLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISD----------- 279
Query: 290 RSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTK--TPCGTVGYTAPEVV 347
SS+ +K+ DFGLS IY + + T CG++ + APE++
Sbjct: 280 -SSE----------------------IKIIDFGLSN-IYDSRKQLHTFCGSLYFAAPELL 315
Query: 348 KDERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGA 406
K Y+ +VD+W G VL+ ++CG PF DE VL EKI +G+ + + +S
Sbjct: 316 KANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQ----HLSIEV 371
Query: 407 KNCVRKLLEVDPAKRYTSEQLLQDPWL 433
+ + K+L VDP +R T +Q+++ W+
Sbjct: 372 ISLLSKMLVVDPKRRATLKQVVEHHWM 398
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 107 bits (266), Expect = 6e-23
Identities = 82/325 (25%), Positives = 147/325 (45%), Gaps = 73/325 (22%)
Query: 114 QTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTN 173
+ ++ Y L +G G F KV G + +VA+K++ +Q++ + +
Sbjct: 12 RVKIGHYILGDTLGVGTFGKVKVGKHELTG-------------HKVAVKILNRQKIRSLD 58
Query: 174 KKG----DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGE 229
G + +N K ++K +++++S+ +I +++ E ++GGE
Sbjct: 59 VVGKIRREIQNLKLFRHPHIIK---LYQVISTPSDI-------------FMVMEYVSGGE 102
Query: 230 IFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKL 289
+F I K E SR + +Q+ + V Y H+ +VHRD+KPEN+L +
Sbjct: 103 LFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD------------ 150
Query: 290 RSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPEVVK 348
K+ADFGLS + +T CG+ Y APEV+
Sbjct: 151 ----------------------AHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVIS 188
Query: 349 DERYS-MQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAK 407
Y+ +VD+W G +LY +LCG PF D+ + L +KI G F P + ++
Sbjct: 189 GRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG--IFYTPQY--LNPSVI 244
Query: 408 NCVRKLLEVDPAKRYTSEQLLQDPW 432
+ ++ +L+VDP KR + + + + W
Sbjct: 245 SLLKHMLQVDPMKRASIKDIREHEW 269
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 107 bits (266), Expect = 6e-23
Identities = 91/316 (28%), Positives = 148/316 (46%), Gaps = 67/316 (21%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y + + IGEG F+KV G +T NG VA+K+I K + +KG E
Sbjct: 12 YEIGRTIGEGNFAKVKLGYDTT----NGTY---------VAVKIIDKALVI---QKGLES 55
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
QV +EI K+++ NIV + ++ I+ E ++GG++ + +
Sbjct: 56 --------QVKREIRTMKLLNH-PNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKM 106
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
D +R + +QL +AV Y H G+ HRD+KP+NLL +
Sbjct: 107 KESD-ARKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLD---------------------- 143
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPEVVKDERYS-MQVD 357
+K++DFGLS + T CG+ Y APE++ ++ YS VD
Sbjct: 144 ------------SKGNLKVSDFGLSAVPKSGDMLSTACGSPCYIAPELIMNKGYSGAAVD 191
Query: 358 MWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVD 417
+W G +L+ +L G+PPF D + VL +KI R +YTF + + K + +L+ +
Sbjct: 192 VWSCGVILFELLAGYPPFDDHTLPVLYKKILRADYTFPPGFTGE----QKRLIFNILDPN 247
Query: 418 PAKRYT-SEQLLQDPW 432
P R T +E +++D W
Sbjct: 248 PLSRITLAEIIIKDSW 263
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 107 bits (266), Expect = 6e-23
Identities = 82/315 (26%), Positives = 133/315 (42%), Gaps = 62/315 (19%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
D+ + + +G G F VY S+ VA+KV+ K QL
Sbjct: 18 DFDIGKPLGRGKFGHVYLAREKRSD-------------HIVALKVLFKAQLQ-------- 56
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
++ Q+ +E+ I + NI+ + +K Y+I E GE++ E+ K
Sbjct: 57 ---QSQVEHQLRREVEIQSHLRH-PNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCK 112
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
YFSE + + LA A+ Y H ++HRDIKPENLL
Sbjct: 113 YFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLI---------------------- 150
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDM 358
+K+ADFG S + +T CGT+ Y PE+V+ + VD+
Sbjct: 151 ------------GAQGELKIADFGWSVHTFNRR-RTMCGTLDYLPPEMVESVEHDASVDI 197
Query: 359 WGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDP 418
W +G + Y L G PPF + ++I + + F P +S AK+ + ++L +
Sbjct: 198 WSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKF--PPKPIVSSSAKDLISQMLVKES 255
Query: 419 AKRYTSEQLLQDPWL 433
+R +LL+ PW+
Sbjct: 256 TQRLALHKLLEHPWI 270
>YOL045w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1101
Score = 106 bits (264), Expect = 1e-22
Identities = 92/366 (25%), Positives = 161/366 (43%), Gaps = 70/366 (19%)
Query: 77 VQIVQGKDGTSQEENTYDESSDATTTPQEEPEDVFPEQTELK---DYTLIQKIGEGAFSK 133
++ + G++ + +S T PE Q +K D+T++Q +GEGA+ K
Sbjct: 795 IEPINGEEIKKETNELDKRNSTLKATYLTTPEANIGSQKRIKKFSDFTILQVMGEGAYGK 854
Query: 134 VYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEI 193
V I + +++ V IK+I K+++ D K G + Q++ +
Sbjct: 855 VNLCIHN-------------REHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATL 901
Query: 194 AIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFG-EIVKYTYFSEDLSRH----V 248
+S ENI+ +DF E + YYYI E GE ++ F +D+ H V
Sbjct: 902 N----KNSQENILKLLDFFEDDDYYYI--ETPVHGETGSIDLFDVIEFKKDMVEHEAKLV 955
Query: 249 IRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXX 308
+Q+ ++K++H GIVHRDIK EN++ + F
Sbjct: 956 FKQVVASIKHLHDQGIVHRDIKDENVIVDSHGF--------------------------- 988
Query: 309 XXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERY-SMQVDMWGVGCVLYT 367
VKL DFG + I GT+ Y APEV+ Y D+W +G +LYT
Sbjct: 989 -------VKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYT 1041
Query: 368 VLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQL 427
++ P+++ ++I GE F + + +S+ + ++++L + KR T +++
Sbjct: 1042 IIYKENPYYN------IDEILEGELRFDKS--EHVSEECISLIKRILTREVDKRPTIDEI 1093
Query: 428 LQDPWL 433
+D WL
Sbjct: 1094 YEDKWL 1099
>CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 856
Score = 106 bits (264), Expect = 1e-22
Identities = 95/336 (28%), Positives = 151/336 (44%), Gaps = 62/336 (18%)
Query: 113 EQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNT 172
EQ + +Y+ +G GAF+ VYRG + + VAIK I K+ + +
Sbjct: 2 EQFDGFEYSKRDLLGHGAFAIVYRG------------RYVDRTDVPVAIKAIAKKNISKS 49
Query: 173 NKKGDEKNGKTSTAEQVLKEIAIHKIVSS--GENIVSFIDFQESEKYYYIIQELLAGGEI 230
KN T KEI I K +SS EN+V + E+ + Y++ E GG++
Sbjct: 50 ------KNLLT-------KEIKILKELSSLKHENLVGLLKCTETPTHVYLVMEFCNGGDL 96
Query: 231 FGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLR 290
+ + T +ED +H + Q+A+A++ +++ GIVHRD+KP+N+L NP
Sbjct: 97 ADYLQQKTTLNEDTIQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQNP----- 151
Query: 291 SSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQ-TNTKTPCGTVGYTAPEVVKD 349
V+KLADFG ++ + T CG+ Y APEV+
Sbjct: 152 -------------------HFTDIVIKLADFGFARFLNDGVMAATLCGSPMYMAPEVIMS 192
Query: 350 ERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRP----WWDQISDG 405
+Y + D+W +G +L+ L G PF + L K + LRP W S
Sbjct: 193 MQYDAKADLWSIGTILFQCLTGKAPFVAQTPPQL--KAYYEKTRELRPNIPEW---CSPN 247
Query: 406 AKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDCLPS 441
++ + +LL+ + R + E P+L S LPS
Sbjct: 248 LRDLLLRLLKRNAKDRISFEDFFNHPFLTS-PLLPS 282
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 106 bits (264), Expect = 1e-22
Identities = 83/315 (26%), Positives = 145/315 (45%), Gaps = 65/315 (20%)
Query: 126 IGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTST 185
+G G F VY GI + NG + VA+K+I K + P K
Sbjct: 776 LGSGQFGTVYGGI----HRRNG---------QHVAVKLIDKLKFP------PNKEDLLRA 816
Query: 186 AEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY---FSE 242
Q+L+++ +V F+ E+ +++ E L G + E++ + SE
Sbjct: 817 EVQILEKV-------DHPGVVHFMQMLETTDRIFVVMEKLKGDML--EMILSSEKGRLSE 867
Query: 243 DLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEG 302
++ ++ Q+ A++Y+H L IVH D+KPEN+L +SD P
Sbjct: 868 RTTQFLVAQILEALRYLHHLNIVHCDLKPENILLN------------SNSDFPQ------ 909
Query: 303 VFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPEVVKDERYSMQVDMWGV 361
VKL DFG ++ I + + ++ GT Y APEV++++ ++ +DMW V
Sbjct: 910 -------------VKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGFNRSLDMWSV 956
Query: 362 GCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKR 421
G ++Y L G PF ++ + + ++I E+ + W +IS+ A + LL+V +KR
Sbjct: 957 GVIVYVSLSGTFPFNED--EDINDQIQNAEFMYPPTPWKEISENAIEFINGLLQVKMSKR 1014
Query: 422 YTSEQLLQDPWLNSY 436
YT + W+ +Y
Sbjct: 1015 YTVTKAQSQIWMQNY 1029
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 106 bits (264), Expect = 1e-22
Identities = 90/335 (26%), Positives = 147/335 (43%), Gaps = 72/335 (21%)
Query: 90 ENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGAS 149
E+ D+ ++ P E + D+ + IG+G+F +VY+
Sbjct: 70 ESPDDDENNVDLGPSER------KTATANDFDYLTTIGKGSFGRVYQ------------- 110
Query: 150 SVIAQQYKEV-AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSF 208
V ++ K++ A+K++ K+ + KK + K+ VL H + S
Sbjct: 111 -VRHKETKKIYAMKILSKEHI---RKKNEVKH--VMAERNVLINNFKHPFLVS-----LH 159
Query: 209 IDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRD 268
FQ EK Y+++ L GGE+F + + +FSE SR ++A A+ Y+H+ I++RD
Sbjct: 160 FSFQNKEKLYFVLDHL-NGGELFSHLQREKHFSESRSRFYAAEIACALGYLHEKNIIYRD 218
Query: 269 IKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIY 328
+KPENLL + D+G + L DFGL K+
Sbjct: 219 LKPENLLLD----------------------DKGY------------LVLTDFGLCKEDM 244
Query: 329 QTN--TKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEK 386
Q + T T CGT Y APE++ + Y VD W +G VLY ++ G PPF+ + + + +K
Sbjct: 245 QGSKTTSTFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDK 304
Query: 387 ISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKR 421
I IS + LL+ D +KR
Sbjct: 305 IINQPLRLKH----NISVPCSELITGLLQKDRSKR 335
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 105 bits (263), Expect = 1e-22
Identities = 86/323 (26%), Positives = 136/323 (41%), Gaps = 71/323 (21%)
Query: 119 DYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDE 178
DY IG+G+FSKV R S +KE AIKV+ K+ + NK
Sbjct: 53 DYVFGDIIGDGSFSKVRRATDKKS-------------WKEYAIKVLDKKYIVKENKV-KY 98
Query: 179 KNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYT 238
N + + ++ I ++ F FQ+ K YY++ EL GE+ I KY
Sbjct: 99 VNIERDSMMRLNGFPGISRL---------FHTFQDDLKLYYVL-ELAPNGELLQYIKKYR 148
Query: 239 YFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTK 298
+ E+ R ++ ++++YMH GI+HRD+KPEN+LF+
Sbjct: 149 FLDENCVRFYAAEILSSIEYMHSCGIIHRDLKPENILFD--------------------- 187
Query: 299 LDEGVFRPXXXXXXXXVVKLADFGLSKQI---------YQTNTKTPCGTVGYTAPEVVKD 349
VK+ DFG +K + Y T + GT Y APE++
Sbjct: 188 -------------GNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPELLSR 234
Query: 350 ERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNC 409
+ S D+W CV+Y ++ G PPF + + +KI EY + +
Sbjct: 235 QVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPK----LLPPDIVPL 290
Query: 410 VRKLLEVDPAKRYTSEQLLQDPW 432
L + P+ R T++Q+ Q P+
Sbjct: 291 FSHLFRIQPSDRSTTQQIKQFPF 313
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 105 bits (263), Expect = 1e-22
Identities = 99/320 (30%), Positives = 149/320 (45%), Gaps = 72/320 (22%)
Query: 120 YTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEK 179
Y L + +G+G + KV R S + VAIK I K ++ DE+
Sbjct: 55 YELQETLGKGTYGKVKRATERFSG-------------RVVAIKSIRKDKIK------DEQ 95
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
+ + +EI I ++ +I+S + E++ II E + GE++ I +
Sbjct: 96 D-----MVHIRREIEIMSSLNH-PHIISIYEVFENKDKIVIIMEYASKGELYDYISERRR 149
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
SE +RH RQ+ +AV Y H+ G+VHRD+K EN+L DD
Sbjct: 150 LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILL----------------DDNCN-- 191
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNT--KTPCGTVGYTAPEVVKDERY-SMQV 356
+K+ADFGLS +YQ + +T CG+ Y +PE+V Y +V
Sbjct: 192 ----------------IKIADFGLSN-LYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEV 234
Query: 357 DMWGVGCVLYTVLCGFPPF--FDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLL 414
D W +G +LYT++ G PF FD K L +IS GEY P Q SD A+ +R +L
Sbjct: 235 DSWALGVLLYTLVYGTMPFDGFDHK--NLIRQISSGEYR--EP--TQPSD-ARGLIRWML 287
Query: 415 EVDPAKRYTSEQLLQDPWLN 434
V+P +R T E + W+N
Sbjct: 288 MVNPDRRATIEDIANHWWVN 307
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 105 bits (263), Expect = 1e-22
Identities = 84/340 (24%), Positives = 149/340 (43%), Gaps = 72/340 (21%)
Query: 87 SQEENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSN 146
S++E+ + + A ++ E L + I+ +G G+F +V
Sbjct: 11 SEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRV------------ 58
Query: 147 GASSVIAQQYKEV----AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSG 202
+ ++KE A+K++ KQ++ K E L E I + V+
Sbjct: 59 -----MLVKHKETGNHYAMKILDKQKVV-----------KLKQIEHTLNEKRILQAVNFP 102
Query: 203 ENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQL 262
+ F+++ Y ++ E + GGE+F + + FSE +R Q+ +Y+H L
Sbjct: 103 FLVKLEFSFKDNSNLY-MVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 161
Query: 263 GIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFG 322
+++RD+KPENLL + +I ++ DFG
Sbjct: 162 DLIYRDLKPENLLIDQQGYI----------------------------------QVTDFG 187
Query: 323 LSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDV 382
+K++ + T T CGT Y APE++ + Y+ VD W +G ++Y + G+PPFF ++
Sbjct: 188 FAKRV-KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQ 246
Query: 383 LTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRY 422
+ EKI G+ F S K+ +R LL+VD KR+
Sbjct: 247 IYEKIVSGKVRFP----SHFSSDLKDLLRNLLQVDLTKRF 282
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 105 bits (263), Expect = 1e-22
Identities = 92/368 (25%), Positives = 154/368 (41%), Gaps = 86/368 (23%)
Query: 76 HVQIVQGKDGTSQEENTYDESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVY 135
H Q S + E+ D T Q P++V +G G F VY
Sbjct: 522 HAPHRQASLSISVSNSQIQENVDIATVYQIFPDEV---------------LGSGQFGVVY 566
Query: 136 RGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAI 195
G + ++VA+KVI K + P T Q+ E+AI
Sbjct: 567 GGKHRKTG-------------RDVAVKVIDKLRFP------------TKQESQLRNEVAI 601
Query: 196 HKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSED------LSRHVI 249
+ + + F+ EK + ++++L G++++ SE L++ +I
Sbjct: 602 LQSLRHPGIVNLECMFETPEKVFVVMEKL------HGDMLEMILSSEKGRLPERLTKFLI 655
Query: 250 RQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXX 309
Q+ A++++H IVH D+KPEN+L D P
Sbjct: 656 TQILVALRHLHFKNIVHCDLKPENVLLASADPFPQ------------------------- 690
Query: 310 XXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTV 368
VKL DFG ++ I + + ++ GT Y APEV+ ++ Y+ +DMW VG ++Y
Sbjct: 691 ------VKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVS 744
Query: 369 LCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLL 428
L G PF ++ + + ++I + + W IS GA + + LL+V KRY+ ++ L
Sbjct: 745 LSGTFPFNED--EDINDQIQNAAFMYPASPWSHISAGAIDLINNLLQVKMRKRYSVDKSL 802
Query: 429 QDPWLNSY 436
PWL Y
Sbjct: 803 SHPWLQEY 810
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 105 bits (262), Expect = 2e-22
Identities = 93/356 (26%), Positives = 150/356 (42%), Gaps = 70/356 (19%)
Query: 104 QEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKV 163
++E E + L Y L + +GEG F KV + S S A+K+
Sbjct: 4 RQEEEKKAEKGMRLGKYELGRTLGEGNFGKVKFAKDTVSGHS-------------FAVKI 50
Query: 164 IIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQE 223
I K ++ + N + Q+ +EI K++ +IV + S+ ++ E
Sbjct: 51 IDKSRIADLN-----------FSLQIKREIRTLKMLKH-PHIVRLHEVLASKTKINMVME 98
Query: 224 LLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIP 283
L+ GGE+F IV +E R + +QL + + Y H G+ HRD+K EN+L + I
Sbjct: 99 LVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHI- 157
Query: 284 NPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSK--QIYQTN--TKTPCGTV 339
K+ DFGLS Q ++ + T CG+
Sbjct: 158 ---------------------------------KITDFGLSALPQHFRDDGLLHTTCGSP 184
Query: 340 GYTAPEVVKDERYSMQV-DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPW 398
Y APEV+ + Y D+W G +LY +L G PF D + VL +KI +G+ P
Sbjct: 185 NYVAPEVLANRGYDGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPI--PR 242
Query: 399 WDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPW--LNSYDCLPSADHSNAPSTGE 452
W +S GA+ ++++L+ +P R T + W L +P D T +
Sbjct: 243 W--LSPGARTMIKRMLDPNPVTRITVVGIKASEWFKLEYIPSIPDDDDEEEVDTDD 296
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 105 bits (262), Expect = 2e-22
Identities = 89/370 (24%), Positives = 162/370 (43%), Gaps = 84/370 (22%)
Query: 77 VQIVQGKDGTSQEENTYDESSDATTTPQEEPEDVFPEQ--TELKDYTLIQKIGEGAFSKV 134
+ +V+ +G S +EN +D + + D+ + D+ +++ +G+GAF KV
Sbjct: 89 IDLVECLEGESLKENDDFSGNDDSDNEKALEGDLVKVSGVVGIDDFEVMKVVGKGAFGKV 148
Query: 135 YRGIPSTSNCSNGASSVIAQQYKEV-AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEI 193
Y+ V ++ E+ A+KV+ K + N + + AE+ +
Sbjct: 149 YQ--------------VRKKETSEIYAMKVMRKDHIMEKN------HAEYMKAERDILTK 188
Query: 194 AIHKIVSSGENIVSFIDFQESEKY-YYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQL 252
H + + + KY Y++ + + GG +F ++ F EDL+R ++
Sbjct: 189 IDHPFIVQ-------LKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEI 241
Query: 253 ANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXX 312
+AV ++H+ GI+HRD+KPEN+L +
Sbjct: 242 VSAVSHLHEKGIMHRDLKPENILMD----------------------------------T 267
Query: 313 XXVVKLADFGLSKQIYQ-TNTKTPCGTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCG 371
V L DFGL+K+ + T + + CGT Y APE+V+ + + D W VG +LY +L G
Sbjct: 268 DGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTG 327
Query: 372 FPPFFDEK----IDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAKRYTS--- 424
PPF K ++ +KI ++ +S+ A ++ LL+ +P +R S
Sbjct: 328 KPPFLGSKGKIQQKIVKDKIKLPQF---------LSNEAHAILKGLLQKEPERRLGSGLS 378
Query: 425 --EQLLQDPW 432
E++ Q W
Sbjct: 379 GAEEIKQHKW 388
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 105 bits (261), Expect = 2e-22
Identities = 80/306 (26%), Positives = 137/306 (44%), Gaps = 64/306 (20%)
Query: 117 LKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKG 176
L+D+ + +G G+F +V +QY A+K++ KQ++
Sbjct: 41 LEDFERKKTLGTGSFGRVML-----------VKHKATEQY--YAMKILDKQKVV------ 81
Query: 177 DEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVK 236
K E L E I + V+ + F+++ Y ++ E + GGE+F + +
Sbjct: 82 -----KLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLY-MVMEYVPGGEMFSHLRR 135
Query: 237 YTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPS 296
FSE +R Q+ +Y+H L +++RD+KPENLL + +I
Sbjct: 136 IGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYI-------------- 181
Query: 297 TKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTPCGTVGYTAPEVVKDERYSMQV 356
++ DFG +K++ + T T CGT Y APE++ + Y+ V
Sbjct: 182 --------------------QVTDFGFAKRV-KGRTWTLCGTPEYLAPEIILSKGYNKAV 220
Query: 357 DMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEV 416
D W +G ++Y + G+PPFF ++ + EKI G+ F S K+ +R LL+V
Sbjct: 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFP----SHFSSDLKDLLRNLLQV 276
Query: 417 DPAKRY 422
D KR+
Sbjct: 277 DLTKRF 282
>Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 105 bits (261), Expect = 2e-22
Identities = 77/282 (27%), Positives = 130/282 (45%), Gaps = 35/282 (12%)
Query: 180 NGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTY 239
N K +QV E+ I + + +V +D E+ Y ++ E+ G + +V++
Sbjct: 33 NKKLMKRDQVTHELGILQSLQH-PLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGS 91
Query: 240 FSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKL 299
+E R + ++ AV+Y+H I H D+KPEN+L +
Sbjct: 92 LTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENIL-----------------------V 128
Query: 300 DEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-TKTPCGTVGYTAPEVVKDERYSMQVDM 358
DE + +P +KLADFG + Q+ T G + APE++ S+ D
Sbjct: 129 DESLAKPT--------IKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDT 180
Query: 359 WGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDP 418
W VG + Y +L G PF D+ ++ I R +++F ++ +S AK V LL+ DP
Sbjct: 181 WSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDP 240
Query: 419 AKRYTSEQLLQDPWLNSYDCLPSA--DHSNAPSTGEKRRHSH 458
AKR ++ LQ+ WL + + + D S S E+R+H +
Sbjct: 241 AKRPSAALALQEQWLQAGNGRSTGVLDTSRLTSFIERRKHQN 282
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 104 bits (260), Expect = 3e-22
Identities = 81/312 (25%), Positives = 143/312 (44%), Gaps = 61/312 (19%)
Query: 112 PEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPN 171
PE+ + + L++ +G+G + KV++ + + + G K A+KV+ K +
Sbjct: 83 PEKIRPECFELLRVLGKGGYGKVFQ-VRKVTGANTG---------KIFAMKVLKKAMIVR 132
Query: 172 TNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIF 231
K + + E+V + I + FQ K Y I+ E L+GGE+F
Sbjct: 133 NAKDTAHTKAERNILEEVKHPFIVDLIYA----------FQTGGKLYLIL-EYLSGGELF 181
Query: 232 GEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRS 291
++ + F ED + + +++ A+ ++HQ GI++RD+KPEN++
Sbjct: 182 MQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLN-------------- 227
Query: 292 SDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQ--TNTKTPCGTVGYTAPEVVKD 349
VKL DFGL K+ T T T CGT+ Y APE++
Sbjct: 228 --------------------HQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMR 267
Query: 350 ERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNC 409
++ VD W +G ++Y +L G PPF E +KI + + L P+ ++ A++
Sbjct: 268 SGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLN-LPPY---LTQEARDL 323
Query: 410 VRKLLEVDPAKR 421
++KLL+ + A R
Sbjct: 324 LKKLLKRNAASR 335
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 104 bits (259), Expect = 4e-22
Identities = 97/351 (27%), Positives = 151/351 (42%), Gaps = 58/351 (16%)
Query: 94 DESSDATTTPQEEPEDVFPEQTELKDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIA 153
++ SD PQ E T Y L +GEG F KV G P N SN ++S
Sbjct: 16 NDLSDTFQYPQRTDEQRRKHVT-FGPYILGSTLGEGEFGKVKLGWPK--NFSNSSNSTFD 72
Query: 154 QQYKEVAIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQE 213
K+VAIK+I + + N +K ++ +EI K +S NIV + +
Sbjct: 73 FP-KQVAIKLIKRDSISNDYRK----------EVKIYREINALKHLSH-PNIVKLEEVLQ 120
Query: 214 SEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPEN 273
+ +Y I+ E GGE + I K E + + QL + V Y+H G+VHRD+K EN
Sbjct: 121 NSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVHRDLKLEN 180
Query: 274 LLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTN-- 331
LL + + + + DFG + N
Sbjct: 181 LLLDKNENL----------------------------------VITDFGFVNEFCSRNEL 206
Query: 332 TKTPCGTVGYTAPE-VVKDERY-SMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISR 389
KT CG+ Y APE V+ E Y + + D+W G +LY +L G+ P+ D+ + I R
Sbjct: 207 MKTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGR 266
Query: 390 GEYTFLR----PWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSY 436
Y ++ + D I ++ +R++L DP KR +Q+ + WL +
Sbjct: 267 -LYNYINSTPLKFPDYILPIPRDLLRRMLVSDPKKRINLKQIKKHEWLKPH 316
>At4g40010 [T] KOG0583 Serine/threonine protein kinase
Length = 350
Score = 104 bits (259), Expect = 4e-22
Identities = 77/252 (30%), Positives = 116/252 (45%), Gaps = 41/252 (16%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSR 246
E V +EI H+ + NI+ F + + + I+ E AGGE+F I FSED R
Sbjct: 43 EHVQREIINHRDLKH-PNIIRFKEVFVTPTHLAIVMEYAAGGELFERICNAGRFSEDEGR 101
Query: 247 HVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRP 306
+ +QL + V Y H + I HRD+K EN L + PS+ L
Sbjct: 102 YYFKQLISGVSYCHAMQICHRDLKLENTLLD---------------GSPSSHL------- 139
Query: 307 XXXXXXXXVVKLADFGLSKQ-IYQTNTKTPCGTVGYTAPEVVKDERYSMQV-DMWGVGCV 364
K+ DFG SK + + K+ GT Y APEV+ + Y+ ++ D+W G
Sbjct: 140 ----------KICDFGYSKSSVLHSQPKSTVGTPAYVAPEVLSRKEYNGKIADVWSCGVT 189
Query: 365 LYTVLCGFPPFFDEK----IDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAK 420
LY +L G PF D + I ++I YT P + +IS K+ + ++ DP K
Sbjct: 190 LYVMLVGAYPFEDPEDPRNIRNTIQRILSVHYTI--PDYVRISSECKHLLSRIFVADPDK 247
Query: 421 RYTSEQLLQDPW 432
R T ++ + PW
Sbjct: 248 RITVPEIEKHPW 259
>At1g78290 [T] KOG0583 Serine/threonine protein kinase
Length = 343
Score = 104 bits (259), Expect = 4e-22
Identities = 76/252 (30%), Positives = 115/252 (45%), Gaps = 41/252 (16%)
Query: 187 EQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKYTYFSEDLSR 246
E V +EI H+ + NI+ F + + + ++ E AGGE+FG I FSED +R
Sbjct: 43 EHVQREIMNHRSLIH-PNIIRFKEVLLTATHLALVMEYAAGGELFGRICSAGRFSEDEAR 101
Query: 247 HVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPSTKLDEGVFRP 306
+QL + V Y H L I HRD+K EN L L S+ P
Sbjct: 102 FFFQQLISGVNYCHSLQICHRDLKLENTL-------------LDGSEAPR---------- 138
Query: 307 XXXXXXXXVVKLADFGLSKQ-IYQTNTKTPCGTVGYTAPEVVKDERYSMQV-DMWGVGCV 364
VK+ DFG SK + + KT GT Y APEV+ + Y ++ D+W G
Sbjct: 139 ---------VKICDFGYSKSGVLHSQPKTTVGTPAYIAPEVLSTKEYDGKIADVWSCGVT 189
Query: 365 LYTVLCGFPPFFD----EKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLEVDPAK 420
LY +L G PF D + +I + +Y P + ++SD ++ + ++ +P K
Sbjct: 190 LYVMLVGAYPFEDPSDPKDFRKTIGRILKAQYAI--PDYVRVSDECRHLLSRIFVANPEK 247
Query: 421 RYTSEQLLQDPW 432
R T E++ W
Sbjct: 248 RITIEEIKNHSW 259
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 104 bits (259), Expect = 4e-22
Identities = 97/361 (26%), Positives = 158/361 (42%), Gaps = 79/361 (21%)
Query: 103 PQEEPEDVFPEQTEL---KDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEV 159
P+++ D+ ++ K Y ++ G+G F+K Y +I + +V
Sbjct: 5 PEDKSTDIPDRLVDINQRKTYKRMRFFGKGGFAKCYE--------------IIDVETDDV 50
Query: 160 -AIKVIIKQQLPNTNKKGDEKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYY 218
A K++ K+ + N+K E+ +EI IH+ ++ NIV F ++ E +
Sbjct: 51 FAGKIVSKKLMIKHNQK-----------EKTAQEITIHRSLNH-PNIVKFHNYFEDSQNI 98
Query: 219 YIIQELLAGGEIFGEIVKYTYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEP 278
YI+ EL + + +E R+ I Q+ VKY+H I+HRD+K NL
Sbjct: 99 YIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLND 158
Query: 279 IDFIPNPKPKLRSSDDPSTKLDEGVFRPXXXXXXXXVVKLADFGLSKQI-YQ-TNTKTPC 336
+ VK+ DFGL+ +I Y+ KT C
Sbjct: 159 L----------------------------------LHVKIGDFGLATRIEYEGERKKTLC 184
Query: 337 GTVGYTAPEVVKDERYSMQVDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEY---T 393
GT Y APE++ + +S +VD+W +GCV+YT+L G PPF + + KI + EY +
Sbjct: 185 GTPNYIAPEILTKKGHSFEVDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVPS 244
Query: 394 FLRPWWDQISDGAKNCVRKLLEVDPAKRYTSEQLLQDPWLNSYDC---LPSADHSNAPST 450
+LR A + V +L+ +P R QLL +L LPS+ + AP
Sbjct: 245 YLR-------KPAADMVIAMLQPNPESRPAIGQLLNFEFLKGSKVPMFLPSSCLTMAPRI 297
Query: 451 G 451
G
Sbjct: 298 G 298
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 103 bits (258), Expect = 5e-22
Identities = 76/300 (25%), Positives = 138/300 (45%), Gaps = 61/300 (20%)
Query: 118 KDYTLIQKIGEGAFSKVYRGIPSTSNCSNGASSVIAQQYKEVAIKVIIKQQLPNTNKKGD 177
+D+ L++ +G+G + KV++ + T+ NG + A+KV+ K + K
Sbjct: 81 EDFQLLKVLGKGGYGKVFQ-VRKTTGSDNG---------QIFAMKVLQKATIVRNQKDTA 130
Query: 178 EKNGKTSTAEQVLKEIAIHKIVSSGENIVSFIDFQESEKYYYIIQELLAGGEIFGEIVKY 237
+ + E V + + FQ K Y I+ E L+GGE+F + +
Sbjct: 131 HTKAERNILEAVKSPFICDLLYA----------FQTGGKLYLIL-EYLSGGELFMHLERE 179
Query: 238 TYFSEDLSRHVIRQLANAVKYMHQLGIVHRDIKPENLLFEPIDFIPNPKPKLRSSDDPST 297
F E++++ + ++ +++++HQ GI++RD+KPEN+L +
Sbjct: 180 GMFMENVAKFYLSEIVVSLEHLHQQGIIYRDLKPENILLDAYGH---------------- 223
Query: 298 KLDEGVFRPXXXXXXXXVVKLADFGLSKQIYQTNTKTP--CGTVGYTAPEVVKDERYSMQ 355
VKL DFGL K+ + + KT CGT+ Y APE++ +
Sbjct: 224 ------------------VKLTDFGLCKEEIEGDQKTHTFCGTIEYMAPEILMRCGHGKA 265
Query: 356 VDMWGVGCVLYTVLCGFPPFFDEKIDVLTEKISRGEYTFLRPWWDQISDGAKNCVRKLLE 415
VD W +G +++ +L G PPF E +KI +G T +S+ A++ ++KLL+
Sbjct: 266 VDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPA----YLSNEARDLIKKLLK 321
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,754,599
Number of Sequences: 60738
Number of extensions: 1367487
Number of successful extensions: 8326
Number of sequences better than 1.0e-05: 754
Number of HSP's better than 0.0 without gapping: 381
Number of HSP's successfully gapped in prelim test: 373
Number of HSP's that attempted gapping in prelim test: 6183
Number of HSP's gapped (non-prelim): 1490
length of query: 546
length of database: 30,389,216
effective HSP length: 111
effective length of query: 435
effective length of database: 23,647,298
effective search space: 10286574630
effective search space used: 10286574630
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)