ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3338 check: MH C KOG2451 Energy production and conversion Aldehyde dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3338 1171910 1170399 -504
(504 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase 484 e-136
YBR006w [C] KOG2451 Aldehyde dehydrogenase 479 e-135
Hs4507229 [C] KOG2451 Aldehyde dehydrogenase 476 e-134
At1g79440 [C] KOG2451 Aldehyde dehydrogenase 462 e-130
7301355 [C] KOG2451 Aldehyde dehydrogenase 450 e-126
SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase 427 e-119
CE10542 [C] KOG2451 Aldehyde dehydrogenase 421 e-117
Hs4502041 [C] KOG2450 Aldehyde dehydrogenase 329 7e-90
At3g48000 [C] KOG2450 Aldehyde dehydrogenase 323 4e-88
Hs10835045 [C] KOG2450 Aldehyde dehydrogenase 323 5e-88
7301524 [C] KOG2450 Aldehyde dehydrogenase 316 5e-86
At1g23800 [C] KOG2450 Aldehyde dehydrogenase 316 6e-86
Hs19923115 [C] KOG2450 Aldehyde dehydrogenase 315 8e-86
Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 315 1e-85
HsM4502031 [C] KOG2450 Aldehyde dehydrogenase 315 1e-85
Hs21361176 [C] KOG2450 Aldehyde dehydrogenase 315 1e-85
SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase 313 4e-85
7297513 [C] KOG2450 Aldehyde dehydrogenase 313 4e-85
CE23852 [C] KOG2450 Aldehyde dehydrogenase 311 2e-84
YER073w [C] KOG2450 Aldehyde dehydrogenase 306 5e-83
Hs11436533 [C] KOG2450 Aldehyde dehydrogenase 303 3e-82
YOR374w [C] KOG2450 Aldehyde dehydrogenase 303 5e-82
Hs4502033 [C] KOG2450 Aldehyde dehydrogenase 296 6e-80
SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase 294 2e-79
Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 294 2e-79
HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 293 5e-79
CE29393 [C] KOG2450 Aldehyde dehydrogenase 293 5e-79
YPL061w [C] KOG2450 Aldehyde dehydrogenase 281 2e-75
YMR170c [C] KOG2450 Aldehyde dehydrogenase 274 2e-73
At3g48170 [C] KOG2450 Aldehyde dehydrogenase 273 3e-73
CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 271 2e-72
YMR169c [C] KOG2450 Aldehyde dehydrogenase 270 4e-72
Hs12007648 [C] KOG2450 Aldehyde dehydrogenase 264 2e-70
CE07233 [C] KOG2450 Aldehyde dehydrogenase 259 9e-69
Hs4502047 [C] KOG2450 Aldehyde dehydrogenase 258 1e-68
CE24573 [C] KOG2450 Aldehyde dehydrogenase 256 6e-68
SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase 251 2e-66
7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 240 3e-63
At1g74920 [C] KOG2450 Aldehyde dehydrogenase 237 3e-62
CE06980 [C] KOG2450 Aldehyde dehydrogenase 224 3e-58
Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 214 3e-55
At2g24270 [C] KOG2450 Aldehyde dehydrogenase 211 2e-54
CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 199 8e-51
7293810 [C] KOG2453 Aldehyde dehydrogenase 189 8e-48
7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 189 8e-48
Hs4557343 [C] KOG2453 Aldehyde dehydrogenase 187 4e-47
At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 185 1e-46
At1g54100 [C] KOG2453 Aldehyde dehydrogenase 180 5e-45
At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase 177 3e-44
CE01232 [C] KOG2453 Aldehyde dehydrogenase 177 3e-44
YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G 172 1e-42
SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase 166 8e-41
Hs21359829 [C] KOG2456 Aldehyde dehydrogenase 156 6e-38
HsM4502035 [C] KOG2456 Aldehyde dehydrogenase 156 8e-38
CE27441 [C] KOG2456 Aldehyde dehydrogenase 149 7e-36
CE13415 [C] KOG2456 Aldehyde dehydrogenase 144 3e-34
Hs4502045 [C] KOG2456 Aldehyde dehydrogenase 139 8e-33
Hs4557303 [C] KOG2456 Aldehyde dehydrogenase 134 4e-31
Hs18603595 [C] KOG2456 Aldehyde dehydrogenase 134 4e-31
Hs4502043 [C] KOG2456 Aldehyde dehydrogenase 130 5e-30
YMR110c [C] KOG2456 Aldehyde dehydrogenase 127 5e-29
At1g44170 [C] KOG2456 Aldehyde dehydrogenase 120 4e-27
CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 120 5e-27
YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 118 2e-26
SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrog... 116 7e-26
7304212 [C] KOG2456 Aldehyde dehydrogenase 116 9e-26
Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 114 3e-25
Hs20546780 [C] KOG2450 Aldehyde dehydrogenase 108 1e-23
7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 104 4e-22
At4g36250 [C] KOG2456 Aldehyde dehydrogenase 101 3e-21
7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 81 3e-15
7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 80 9e-15
Hs20481620 [C] KOG2456 Aldehyde dehydrogenase 74 5e-13
At4g34240 [C] KOG2456 Aldehyde dehydrogenase 65 3e-10
Hs20479244 [C] KOG2450 Aldehyde dehydrogenase 63 9e-10
>SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase
Length = 498
Score = 484 bits (1245), Expect = e-136
Identities = 244/478 (51%), Positives = 338/478 (70%), Gaps = 10/478 (2%)
Query: 30 KAFINGKWTE--TDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRE 87
+++I GKW + F V NP +T+ VT+ V + KAI++AH+AF ++R ++++E
Sbjct: 25 RSYIGGKWVTAASGKTFDVENPGLNETLAPVTDMSVEETRKAIKVAHEAFLSYRNSDIKE 84
Query: 88 RAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDII 147
R IL Y+L++EN DLA ++TLENGK D+ GE+VY+A F WFA EA RI GD
Sbjct: 85 RYAILRRWYDLIMENADDLATMMTLENGKALGDAKGEVVYAAKFIDWFAGEALRISGD-- 142
Query: 148 PSAVSSD--QKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLS 205
S++SS+ +I TI+QP+GV+GI+TPWNFP+AMI RK+ +A G T VI+PA ETP +
Sbjct: 143 -SSMSSNPQNRIITIKQPVGVVGIITPWNFPAAMITRKVGAALAAGCTVVIRPAAETPFT 201
Query: 206 ALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSK 265
ALAL +AE+AG+PAGV N++ N SE G + + L++K++FTGST +G++L QSS
Sbjct: 202 ALALAKLAERAGVPAGVLNMVTANSPSEHGIELTTNPLIRKVSFTGSTNVGKILAKQSSS 261
Query: 266 GKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEF 325
+KK S+ELGGNAP+IVF+DADL++A D ++ CKFR SGQTC+CANRI+VH +YD F
Sbjct: 262 --TLKKLSLELGGNAPFIVFEDADLEKAADALMACKFRGSGQTCVCANRIYVHSSVYDAF 319
Query: 326 SKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSL 385
+ +++ K FKLG G GVTHGPLI +K+I KV V+DA KG V+ GG AS+L
Sbjct: 320 VDLVTERVSK-FKLGYGLDAGVTHGPLISEKAISKVKQHVEDAVQKGGVVVTGGKVASNL 378
Query: 386 GPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNI 445
GP++++PTV+ N + M I EE FGPV L KF DEV+ AND+ VGLAGY +S++I
Sbjct: 379 GPMYFEPTVIINAKQGMLISEEETFGPVGALFKFDTEDEVVAWANDSPVGLAGYLFSKDI 438
Query: 446 STIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIVA 503
S +F E L VGMVG NTG +S+ PFGGVK SG G+EGSKYGI +Y ++K++ ++
Sbjct: 439 SRVFRVGEALQVGMVGCNTGLVSDVLSPFGGVKESGFGREGSKYGISEYLDIKSLTIS 496
>YBR006w [C] KOG2451 Aldehyde dehydrogenase
Length = 497
Score = 479 bits (1232), Expect = e-135
Identities = 243/490 (49%), Positives = 338/490 (68%), Gaps = 7/490 (1%)
Query: 16 KMSSKIEND-YLIQTKAFINGKWTE-TDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIA 73
K S ND L + +I+GKW + TD+ F V +P++G+ I V VS +AI++A
Sbjct: 5 KYSKPTLNDPNLFRESGYIDGKWVKGTDEVFEVVDPASGEIIARVPEQPVSVVEEAIDVA 64
Query: 74 HDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFK 133
++ F T++ T RERA+ L N+YNLMLEN DLA I+TLENGK ++ GEI Y+A +F+
Sbjct: 65 YETFKTYKNTTPRERAKWLRNMYNLMLENLDDLATIITLENGKALGEAKGEIKYAASYFE 124
Query: 134 WFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNT 193
W+AEEAPR+YG I ++ ++FTIRQP+GV GI+ PWNFPSAMI RK A +A G T
Sbjct: 125 WYAEEAPRLYGATI-QPLNPHNRVFTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCT 183
Query: 194 CVIKPAHETPLSALALGVIAEKAGLPAGVCNILPTN-HTSEIGEYVCEHELVKKITFTGS 252
VIKP +TPLSALA+ +AEKAG P G N++ ++ +T ++G+ +CE VKK+TFTGS
Sbjct: 184 VVIKPDSQTPLSALAMAYLAEKAGFPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGS 243
Query: 253 TKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICA 312
T +G++LM QSS +KK S ELGGNAP+IVF+DADLD+AL+ + CKFR GQTC+CA
Sbjct: 244 TNVGKILMKQSSS--TLKKLSFELGGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCA 301
Query: 313 NRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKG 372
NR++VH + D+F+K L +++ K F +G G THG +I+ +I+KV QDA KG
Sbjct: 302 NRLYVHSSIIDKFAKLLAERVKK-FVIGHGLDPKTTHGCVINSSAIEKVERHKQDAIDKG 360
Query: 373 ADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDT 432
A V++ G R + LGP FY P +L +V + + EE FGP+ P+ F ++EV+ ANDT
Sbjct: 361 AKVVLEGGRLTELGPNFYAPVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDT 420
Query: 433 DVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGID 492
+ GLA Y +S+N++T++ +E L GMV NTG S+ ++PFGGVK SG G+EGS YGI+
Sbjct: 421 EFGLAAYVFSKNVNTLYTVSEALETGMVSCNTGVFSDCSIPFGGVKESGFGREGSLYGIE 480
Query: 493 DYTELKAIIV 502
DYT LK I +
Sbjct: 481 DYTVLKTITI 490
>Hs4507229 [C] KOG2451 Aldehyde dehydrogenase
Length = 535
Score = 476 bits (1225), Expect = e-134
Identities = 232/477 (48%), Positives = 336/477 (69%), Gaps = 6/477 (1%)
Query: 26 LIQTKAFINGKWTETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNV 85
L++T +F+ G+W F V +P++G + V +CGV + A+ A++AF +R+ +
Sbjct: 58 LLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSA 117
Query: 86 RERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGD 145
+ER+ +L YNLM++NK DLA+I+T E+GKP K++ GEI+YSA F +WF+EEA R+YGD
Sbjct: 118 KERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGD 177
Query: 146 IIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLS 205
II + + D++ ++QP+GV ++TPWNFPSAMI RK+ +A G T V+KPA +TP S
Sbjct: 178 IIHTP-AKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFS 236
Query: 206 ALALGVIAEKAGLPAGVCNILPTN--HTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQS 263
ALAL +A +AG+P+GV N++P + + E+GE +C LV KI+FTGST G++L+ +
Sbjct: 237 ALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHA 296
Query: 264 SKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYD 323
+ ++K+ SMELGG AP+IVF A++D+A+ G + KFR +GQTC+C+N+ V ++D
Sbjct: 297 AN--SVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHD 354
Query: 324 EFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRAS 383
F K + + K ++G+GF++G T GPLI++K+++KV V DA +KGA V+ GG R
Sbjct: 355 AFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKR-H 413
Query: 384 SLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQ 443
LG F++PT+L NVT+ M +EE FGP+AP+IKF +E I AN DVGLAGYFYSQ
Sbjct: 414 QLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQ 473
Query: 444 NISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
+ + I+ AE+L VGMVGVN G IS PFGGVK SGLG+EGSKYGID+Y ELK +
Sbjct: 474 DPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYV 530
>At1g79440 [C] KOG2451 Aldehyde dehydrogenase
Length = 528
Score = 462 bits (1189), Expect = e-130
Identities = 229/486 (47%), Positives = 339/486 (69%), Gaps = 8/486 (1%)
Query: 17 MSSKIENDYLIQTKAFINGKWTETDDK--FAVTNPSTGDTIREVTNCGVSDFNKAIEIAH 74
+S K+ + L++T+ I GKW ++ D V NP+TG+ I +V G + N AI ++
Sbjct: 41 VSEKLRSSGLLRTQGLIGGKWLDSYDNKTIKVNNPATGEIIADVACMGTKETNDAIASSY 100
Query: 75 DAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKW 134
+AF ++ + ER+++L Y+L++ +K++L +++TLE GKP K+++GE+ Y A F ++
Sbjct: 101 EAFTSWSRLTAGERSKVLRRWYDLLIAHKEELGQLITLEQGKPLKEAIGEVAYGASFIEY 160
Query: 135 FAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTC 194
+AEEA R+YGDIIP +S D+++ ++QP+GV+G +TPWNFP AMI RK+ P +A+G T
Sbjct: 161 YAEEAKRVYGDIIPPNLS-DRRLLVLKQPVGVVGAITPWNFPLAMITRKVGPALASGCTV 219
Query: 195 VIKPAHETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTK 254
V+KP+ TPL+ALA +A +AG+P G N++ N EIG+ + V+KITFTGST
Sbjct: 220 VVKPSELTPLTALAAAELALQAGVPPGALNVVMGN-APEIGDALLTSPQVRKITFTGSTA 278
Query: 255 IGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANR 314
+G+ LM ++ +KK S+ELGGNAP IVF DADLD A+ G + KFR SGQTC+CANR
Sbjct: 279 VGKKLMAAAAP--TVKKVSLELGGNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANR 336
Query: 315 IFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGAD 374
+ V + +YD+F++ + + K ++GDGF+DG T GPLI+D ++ KV + VQDA +KGA
Sbjct: 337 VLVQDGIYDKFAEAFSEAVQK-LEVGDGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAK 395
Query: 375 VLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDV 434
++IGG R SLG FY+PTV+ +V+++M + EEIFGPVAPLI+FK ++ I+ ANDT
Sbjct: 396 IIIGGKR-HSLGMTFYEPTVIRDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIA 454
Query: 435 GLAGYFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDY 494
GLA Y ++ ++ + E L G+VGVN G IS PFGGVK SGLG+EGSKYG+D+Y
Sbjct: 455 GLAAYIFTNSVQRSWRVFEALEYGLVGVNEGLISTEVAPFGGVKQSGLGREGSKYGMDEY 514
Query: 495 TELKAI 500
E+K +
Sbjct: 515 LEIKYV 520
>7301355 [C] KOG2451 Aldehyde dehydrogenase
Length = 509
Score = 450 bits (1157), Expect = e-126
Identities = 221/480 (46%), Positives = 329/480 (68%), Gaps = 9/480 (1%)
Query: 26 LIQTKAFINGKWTETDDK---FAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGT--F 80
L+Q KA ++G W ++ + F V NP+ G I +V N V+D KAI+ A A+ + +
Sbjct: 26 LVQDKALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEW 85
Query: 81 RQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAP 140
R ++R+ +L + L+ ++ Q++A+I+T E+GKP +S GE+ Y F +WFAEEA
Sbjct: 86 RSLTAKDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFAEEAR 145
Query: 141 RIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAH 200
RIYG+I+PSA S +++I ++QP+GV ++TPWNFP AMI RK +A G T V+KP+
Sbjct: 146 RIYGEIVPSA-SPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSE 204
Query: 201 ETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLM 260
+TPL+ALA+ +A AG+P GV N++ TN + IG+ C+ V+ I+FTGST++G+LL
Sbjct: 205 DTPLTALAVAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLF 264
Query: 261 GQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHED 320
S+ G IK+ +ELGGNAP+IVF AD+++A+DG + KFR GQTC+ ANR FV +
Sbjct: 265 RNSADG--IKRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDS 322
Query: 321 LYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGS 380
+YD+F +L +++ K+GDG V GPLI++ +KV+ V+DA++K A++++GG
Sbjct: 323 VYDKFVGQLKKRVE-ALKIGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQ 381
Query: 381 RASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYF 440
G LFY PT++ +V S ++ EE+FGPV +I+F+D +E +K+ANDT GLAGYF
Sbjct: 382 PLPDKGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYF 441
Query: 441 YSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
YS+N+ +F A++L VGMVGVN G IS PFGGVK SG+G+EGSK+GIDDY ++K I
Sbjct: 442 YSENLQQVFRVAKRLEVGMVGVNEGIISAAEAPFGGVKESGVGREGSKHGIDDYVDIKYI 501
>SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase
Length = 493
Score = 427 bits (1098), Expect = e-119
Identities = 208/473 (43%), Positives = 310/473 (64%), Gaps = 5/473 (1%)
Query: 30 KAFINGKWTETDDK--FAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRE 87
++F+ GKW + + F V NP+TG+ I +V + V + KAI A++AF T++ +
Sbjct: 19 QSFVQGKWISSPNNKTFEVDNPATGEIIGKVADVSVEETKKAISAANEAFKTYKNFTHVQ 78
Query: 88 RAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDII 147
R+Q+L+ L++ENK DL K+LTLENGKP + E+ + + KW+A EA R +GD+
Sbjct: 79 RSQLLERWAELIMENKDDLVKMLTLENGKPLSQAEMEVTTCSGYLKWYAAEAVRTFGDVA 138
Query: 148 PSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSAL 207
PS++ S + +I+QP+GV ++TPWNFP+AMIARK +A G T + PA TP L
Sbjct: 139 PSSLQSQNFLISIKQPVGVSALITPWNFPAAMIARKGGAALAAGCTAIFLPAFRTPYVCL 198
Query: 208 ALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGK 267
L +A++AG P GV N++ ++ S G+ + + +V+K++FTGST +G++LMGQS+
Sbjct: 199 GLVRLAQEAGFPDGVLNVITSSDASAHGKELTTNPIVRKVSFTGSTNVGKILMGQSA--S 256
Query: 268 NIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSK 327
IKK SMELGGNAP+IVF D +D+A++ KF GQ C+C NR++VH+++YDEF
Sbjct: 257 TIKKVSMELGGNAPFIVFPDFPIDQAVESFCTIKFNSCGQVCVCPNRVYVHKNVYDEFVS 316
Query: 328 RLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGP 387
+L +K+ KT K+GDGF GPLI KV+ ++DA +KGA + +GG SS
Sbjct: 317 KLTEKV-KTIKVGDGFDSSSAVGPLISQDGCKKVSKHIEDAVSKGAKITVGGKEISSSKG 375
Query: 388 LFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNIST 447
F++PTVL VT+ M + EE FGP+A + KF D +EVI+ AND+DVGLAGY ++ N+ST
Sbjct: 376 YFFEPTVLSGVTQDMLVASEETFGPLASVFKFDDTEEVIEWANDSDVGLAGYVFTNNLST 435
Query: 448 IFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
+ A++L VG+VG N + EP + FGG+K SG GKE + G+ ++ +K I
Sbjct: 436 MIHVAKELEVGLVGANIEMVDEPFISFGGIKQSGFGKEAGRLGVQEFMVVKEI 488
>CE10542 [C] KOG2451 Aldehyde dehydrogenase
Length = 569
Score = 421 bits (1083), Expect = e-117
Identities = 216/479 (45%), Positives = 314/479 (65%), Gaps = 10/479 (2%)
Query: 30 KAFINGKWT--ETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQT-NVR 86
+A+I GKWT ET + F V NP + + TNC V D KA+ A + F + T + +
Sbjct: 19 QAYIGGKWTASETGNSFDVLNPFNNEVVDRATNCTVKDAEKAVHSALEGFDKWAHTYSAK 78
Query: 87 ERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDI 146
+R IL + ++++ + +LA +LT E GKP ++ GEI YSA +F W+A EA R+YG +
Sbjct: 79 QRGAILHKWFEILVQRETELATLLTKEQGKPLAEARGEIQYSAAYFDWYAGEARRVYGQV 138
Query: 147 IPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSA 206
+PSAV + + T R+P+GV+ ++ PWNFP+AMIARK A ++ G + V+KP+ +TPLSA
Sbjct: 139 VPSAVVNRLHLHT-REPIGVVALIAPWNFPTAMIARKAAAALSVGCSAVVKPSGDTPLSA 197
Query: 207 LALGVIAEKAGLPAGVCNILPTNH--TSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSS 264
LAL AE+AG+PAGV N++ +H T+EI +Y+CE V I+FTGST +G+LL+ QS+
Sbjct: 198 LALAQTAEEAGIPAGVFNVITADHSNTAEISKYLCESTDVSAISFTGSTPVGKLLLAQSA 257
Query: 265 KGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDE 324
+K+ +ELGGNAP IVF DADLD A++G + KFR SGQTC+ ANRI+VHE ++D+
Sbjct: 258 S--TVKRVCLELGGNAPLIVFDDADLDVAVNGTMATKFRCSGQTCVSANRIYVHEKIHDQ 315
Query: 325 FSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASS 384
+ +L + + LGDG T GPL++ K++DK L+ DA KG++++ GG R
Sbjct: 316 YISKLAAAMKEKLVLGDGLNPKTTQGPLVNQKAVDKCELLLSDALGKGSELICGGKRGEH 375
Query: 385 LGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQN 444
Y+PT++ NV + +I + EIFGP+A + KF+D EV++ AN+ VGLAGY + ++
Sbjct: 376 --GTSYEPTLITNVQSNTNIAHTEIFGPIASVQKFRDEQEVLEAANNCRVGLAGYVFGRD 433
Query: 445 ISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIVA 503
S + A KL VGMVGVN G IS FGGVK SG+G+EG GID++T + A
Sbjct: 434 QSRLQRVARKLEVGMVGVNEGLISCAEAAFGGVKESGIGREGGAQGIDEFTNWNCRVAA 492
>Hs4502041 [C] KOG2450 Aldehyde dehydrogenase
Length = 512
Score = 329 bits (843), Expect = 7e-90
Identities = 190/480 (39%), Positives = 274/480 (56%), Gaps = 12/480 (2%)
Query: 29 TKAFINGKWTETDD--KFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF---GTFRQT 83
TK FIN +W E+ KFA NPST + I EV D +KA+E A AF +R+
Sbjct: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91
Query: 84 NVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLG-EIVYSAMFFKWFAEEAPRI 142
+ R ++L + +L+ ++ LA + T++ GKP+ + ++ ++FA A +I
Sbjct: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151
Query: 143 YGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHET 202
G IP+ + FT +P+GV G +TPWNFP M+ KLAP + GNT V+KPA +T
Sbjct: 152 QGKTIPT--DDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209
Query: 203 PLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQ 262
PL+AL LG + ++AG P GV NI+P +G + H + KI FTGST++G+L+
Sbjct: 210 PLTALYLGSLIKEAGFPPGVVNIVP-GFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEA 268
Query: 263 SSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLY 322
+S+ N+K+ ++ELGG P IV DADLD A++ F GQ C A+R+FV E +Y
Sbjct: 269 ASRS-NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327
Query: 323 DEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRA 382
EF +R V+ K +GD F GP I K DK+ L++ K +GA + GGS
Sbjct: 328 SEFVRRSVEYAKKR-PVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAM 386
Query: 383 SSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYS 442
G LF +PTV VT++M I EEIFGPV P++KFK ++EVIKRAN TD GL ++
Sbjct: 387 EDKG-LFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFT 445
Query: 443 QNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
+N+ A L G V +N PFGG K SG G+E +Y + +YTE+K + +
Sbjct: 446 KNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTI 505
>At3g48000 [C] KOG2450 Aldehyde dehydrogenase
Length = 538
Score = 323 bits (828), Expect = 4e-88
Identities = 182/480 (37%), Positives = 282/480 (57%), Gaps = 11/480 (2%)
Query: 29 TKAFINGKWTETDD--KFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF--GTFRQTN 84
T+ ING + ++ F +P TG+ I V D N+A++ A AF G + + +
Sbjct: 58 TQLLINGNFVDSASGKTFPTLDPRTGEVIAHVAEGDAEDINRAVKAARTAFDEGPWPKMS 117
Query: 85 VRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSL-GEIVYSAMFFKWFAEEAPRIY 143
ER+++L +L+ ++ ++LA + T +NGKPY+ SL EI A F+++A A +I+
Sbjct: 118 AYERSRVLLRFADLVEKHSEELASLETWDNGKPYQQSLTAEIPMFARLFRYYAGWADKIH 177
Query: 144 GDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETP 203
G IP+ + ++ T+ +P+GV G + PWNFP M A K+ P +A GNT V+K A +TP
Sbjct: 178 GLTIPA--DGNYQVHTLHEPIGVAGQIIPWNFPLLMFAWKVGPALACGNTIVLKTAEQTP 235
Query: 204 LSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQS 263
L+A G + +AGLP GV NI+ + + G + H V K+ FTGST G++++G +
Sbjct: 236 LTAFYAGKLFLEAGLPPGVLNIV-SGFGATAGAALASHMDVDKLAFTGSTDTGKVILGLA 294
Query: 264 SKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYD 323
+ N+K ++ELGG +P+IVF+DAD+D+A++ F GQ C +R FVHE +YD
Sbjct: 295 ANS-NLKPVTLELGGKSPFIVFEDADIDKAVELAHFALFFNQGQCCCAGSRTFVHEKVYD 353
Query: 324 EFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRAS 383
EF ++ + K +GD F+ G+ GP I K +KV ++ A + GG +
Sbjct: 354 EFVEKSKARALKRV-VGDPFRKGIEQGPQIDLKQFEKVMKYIKSGIESNATLECGGDQIG 412
Query: 384 SLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQ 443
G F QPTV NV + M I +EIFGPV ++KF DVDEVIKRAN+T GLA +++
Sbjct: 413 DKG-YFIQPTVFSNVKDDMLIAQDEIFGPVQSILKFSDVDEVIKRANETKYGLAAGVFTK 471
Query: 444 NISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIVA 503
N+ T + L G V VN ++ + A+PFGG K SG G+E Y +++Y ++KA++ A
Sbjct: 472 NLDTANRVSRALKAGTVWVNCFDVFDAAIPFGGYKMSGNGREKGIYSLNNYLQIKAVVTA 531
>Hs10835045 [C] KOG2450 Aldehyde dehydrogenase
Length = 518
Score = 323 bits (827), Expect = 5e-88
Identities = 182/480 (37%), Positives = 277/480 (56%), Gaps = 12/480 (2%)
Query: 29 TKAFINGKW--TETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFG---TFRQT 83
TK FIN +W +E+ F V NP+TG+ + EV +D +KA++ A AF +R+
Sbjct: 38 TKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRM 97
Query: 84 NVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAM-FFKWFAEEAPRI 142
+ ER ++LD + +L+ ++ LA + +L GKP+ + + + F+++A A +I
Sbjct: 98 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 157
Query: 143 YGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHET 202
+G IP V D FT +P+GV G + PWNFP M A K+AP + GNT VIKPA +T
Sbjct: 158 HGMTIP--VDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQT 215
Query: 203 PLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQ 262
PLSAL +G + ++AG P GV NILP + G + H + KI FTGST++G+L+
Sbjct: 216 PLSALYMGALIKEAGFPPGVINILP-GYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEA 274
Query: 263 SSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLY 322
+ + N+K+ ++ELGG +P I+F DADLD A++ F GQ C +RIFV E +Y
Sbjct: 275 AGRS-NLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333
Query: 323 DEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRA 382
+EF +R V++ + +G F GP I K +K+ L+Q +GA + GG
Sbjct: 334 EEFVRRSVERAKRRI-VGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGL 392
Query: 383 SSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYS 442
G F +PTV NVT+ M I EEIFGPV +++FK +DEVI+RAN++D GL ++
Sbjct: 393 GRKG-FFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFT 451
Query: 443 QNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
+I+ + + G V +N PFGG K SG G+E ++G+ +Y+E+K + V
Sbjct: 452 NDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTV 511
>7301524 [C] KOG2450 Aldehyde dehydrogenase
Length = 659
Score = 316 bits (810), Expect = 5e-86
Identities = 173/477 (36%), Positives = 277/477 (57%), Gaps = 12/477 (2%)
Query: 29 TKAFINGKWTET--DDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF---GTFRQT 83
TK FIN ++ ++ FA NP+T I +V+ +D + A++ A AF +R+
Sbjct: 185 TKLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKL 244
Query: 84 NVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIY 143
+ +R +++ + LM +K LA + T +NGKPY ++L ++ YS + +++A + +
Sbjct: 245 SPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEALFDVTYSILTLQYYAGWTDKFF 304
Query: 144 GDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETP 203
GD IP+ T ++P+GV+G + PWN+P M+A K P +A G T ++KPA +TP
Sbjct: 305 GDTIPAGGFVSM---TRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTP 361
Query: 204 LSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQS 263
L+AL + +A++AG PAGV N++ G + H + K+ FTGS +IG+++M Q+
Sbjct: 362 LTALHMAALAKEAGFPAGVINVV-NGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVM-QA 419
Query: 264 SKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYD 323
+ N+K+ S+ELGG +P +VF DAD+D A++ F GQ+C +R +VHE +YD
Sbjct: 420 AATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYD 479
Query: 324 EFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRAS 383
EF + K K K+G+ F+ V GP I D + KV ++ K +GA + GG R
Sbjct: 480 EFVAKAAAKA-KARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIG 538
Query: 384 SLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQ 443
++G F +PTV +V + M I EEIFGPV + KF ++E+I RAN+ GLA +
Sbjct: 539 NVG-FFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITN 597
Query: 444 NISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
+I+ A ++ G V +N + P+ PFGG K+SG+G+E K G+D+Y E K I
Sbjct: 598 DINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTI 654
>At1g23800 [C] KOG2450 Aldehyde dehydrogenase
Length = 508
Score = 316 bits (809), Expect = 6e-86
Identities = 174/480 (36%), Positives = 282/480 (58%), Gaps = 11/480 (2%)
Query: 29 TKAFINGKWTE--TDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF--GTFRQTN 84
T+ I G++ + + F +P G+ I +V+ D N+A+ A AF G + +
Sbjct: 28 TQLLIGGRFVDAVSGKTFPTLDPRNGEVIAQVSEGDAEDVNRAVAAARKAFDEGPWPKMT 87
Query: 85 VRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLG-EIVYSAMFFKWFAEEAPRIY 143
ER++IL +L+ ++ ++A + T +NGKPY+ S E+ A F+++A A +I+
Sbjct: 88 AYERSKILFRFADLIEKHNDEIAALETWDNGKPYEQSAQIEVPMLARVFRYYAGWADKIH 147
Query: 144 GDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETP 203
G +P + T+ +P+GV G + PWNFP M++ KL P +A GNT V+K A +TP
Sbjct: 148 GMTMPG--DGPHHVQTLHEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTP 205
Query: 204 LSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQS 263
LSAL +G + +AGLP GV NI+ + + G + H V K+ FTGST +G++++ +
Sbjct: 206 LSALLVGKLLHEAGLPDGVVNIV-SGFGATAGAAIASHMDVDKVAFTGSTDVGKIILELA 264
Query: 264 SKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYD 323
SK N+K ++ELGG +P+IV +DAD+D+A++ F GQ C +R FVHE +YD
Sbjct: 265 SKS-NLKAVTLELGGKSPFIVCEDADVDQAVELAHFALFFNQGQCCCAGSRTFVHERVYD 323
Query: 324 EFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRAS 383
EF ++ + K +GD F+ G+ GP + + +K+ ++ GA + GG R
Sbjct: 324 EFVEKAKARALKR-NVGDPFKSGIEQGPQVDSEQFNKILKYIKHGVEAGATLQAGGDRLG 382
Query: 384 SLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQ 443
S G + QPTV +V + M I +EIFGPV ++KFKD+DEVI RAN++ GLA ++Q
Sbjct: 383 SKG-YYIQPTVFSDVKDDMLIATDEIFGPVQTILKFKDLDEVIARANNSRYGLAAGVFTQ 441
Query: 444 NISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIVA 503
N+ T L VG V +N ++ + ++PFGG K SG+G+E Y +++Y ++KA++ +
Sbjct: 442 NLDTAHRLMRALRVGTVWINCFDVLDASIPFGGYKMSGIGREKGIYSLNNYLQVKAVVTS 501
>Hs19923115 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 315 bits (808), Expect = 8e-86
Identities = 184/495 (37%), Positives = 285/495 (57%), Gaps = 18/495 (3%)
Query: 17 MSSKIENDYLIQTKAFINGKWTETDDK--FAVTNPSTGDTIREVTNCGVSDFNKAIEIAH 74
+ S I N + + FIN +W + K F NP+TG+ I V +D ++A++ A
Sbjct: 25 LPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAR 84
Query: 75 DAF---GTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDS----LGEIVY 127
+AF +R+ + ER ++L+ + +L+ ++ LA + TL+NGKP+++S L E++
Sbjct: 85 EAFRLGSPWRRMDASERGRLLNLLADLVERDRVYLASLETLDNGKPFQESYALDLDEVI- 143
Query: 128 SAMFFKWFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPV 187
+++FA A + +G IP + FT +P+GV G + PWNFP M KLAP
Sbjct: 144 --KVYRYFAGWADKWHGKTIP--MDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPA 199
Query: 188 IATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKI 247
+ATGNT V+K A +TPLSAL L + ++AG P GV NI+ T + G + +H V K+
Sbjct: 200 LATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNII-TGYGPTAGAAIAQHMDVDKV 258
Query: 248 TFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQ 307
FTGST++G L+ +++ N+K+ ++ELGG +P IV DAD++ A++ F GQ
Sbjct: 259 AFTGSTEVGHLIQ-KAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQ 317
Query: 308 TCICANRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQD 367
C +R FV E +Y+EF +R V+K K K+G+ F+ GP + + ++V +Q
Sbjct: 318 CCCAGSRTFVEESIYNEFLERTVEKA-KQRKVGNPFELDTQQGPQVDKEQFERVLGYIQL 376
Query: 368 AKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIK 427
+ +GA +L GG R G F +PTV G V + M I EEIFGPV PL KFK ++EV++
Sbjct: 377 GQKEGAKLLCGGERFGERG-FFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVE 435
Query: 428 RANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGS 487
RAN+T GLA +++++ + L G V VNT I PFGG K SG G+E
Sbjct: 436 RANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELG 495
Query: 488 KYGIDDYTELKAIIV 502
+ G+ YTE+K + +
Sbjct: 496 EDGLKAYTEVKTVTI 510
>Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 975
Score = 315 bits (807), Expect = 1e-85
Identities = 185/478 (38%), Positives = 283/478 (58%), Gaps = 15/478 (3%)
Query: 19 SKIENDYLIQT--KAFINGKWTETDD--KFAVTNPSTGDTIREVTNCGVSDFNKAIEIAH 74
SK N+ +++ + FING++T+ DD + NP+ G TI +V+ ++D +KA+ A
Sbjct: 431 SKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAK 490
Query: 75 DAF--GTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLG-EIVYSAMF 131
DAF G + + N RER +++ + +L+ EN+++LA I L++G Y +L I S
Sbjct: 491 DAFENGEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQT 550
Query: 132 FKWFAEEAPRIYGDIIP--SAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIA 189
F++FA +I G IP A + FT ++PLGV I+ PWN+P M+A K A +A
Sbjct: 551 FRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLA 610
Query: 190 TGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITF 249
GNT V+KPA TPL+AL ++ KAG P GV NI+P G+ + EH ++K+ F
Sbjct: 611 AGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIP-GSGGIAGQRLSEHPDIRKLGF 669
Query: 250 TGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTC 309
TGST IG+ +M +S N+KK S+ELGG +P I+F D +LD+A+ +G F G+ C
Sbjct: 670 TGSTPIGKQIM-KSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENC 728
Query: 310 ICANRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAK 369
I A R+FV E ++DEF R+V++I K K+GD HGP H ++K+ +
Sbjct: 729 IAAGRLFVEESIHDEFVTRVVEEI-KKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGV 787
Query: 370 TKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFK--DVDEVIK 427
+GA ++ GG + G F +PTV +V + M + EE FGP+ + KF+ D+D V++
Sbjct: 788 KEGATLVYGGRQVQRPG-FFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQ 846
Query: 428 RANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKE 485
RAN T+ GLA ++++I+ +EKL G V +NT ++ A PFGGVK SG GK+
Sbjct: 847 RANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKD 904
>HsM4502031 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 315 bits (806), Expect = 1e-85
Identities = 182/480 (37%), Positives = 277/480 (56%), Gaps = 12/480 (2%)
Query: 29 TKAFINGKWTET--DDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF---GTFRQT 83
TK FIN +W ++ KF V NP+T + + +V D +KA++ A AF +R
Sbjct: 21 TKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTM 80
Query: 84 NVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDS-LGEIVYSAMFFKWFAEEAPRI 142
+ ER ++L + +L+ ++ LA + ++ GK Y ++ L ++ ++ A A +I
Sbjct: 81 DASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLSDLAGCIKTLRYCAGWADKI 140
Query: 143 YGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHET 202
G IP + + +T +P+GV G + PWNFP M+ K+ P ++ GNT V+KPA +T
Sbjct: 141 QGRTIP--IDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQT 198
Query: 203 PLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQ 262
PL+AL + + ++AG P GV NI+P + G + H + K+ FTGST++G+L+
Sbjct: 199 PLTALHVASLIKEAGFPPGVVNIVP-GYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEA 257
Query: 263 SSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLY 322
+ K N+K+ ++ELGG +P IV DADLD A++ F GQ CI A+RIFV E +Y
Sbjct: 258 AGKS-NLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIY 316
Query: 323 DEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRA 382
DEF +R V++ K + LG+ GVT GP I + DK+ L++ K +GA + GG
Sbjct: 317 DEFVRRSVERAKK-YILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPW 375
Query: 383 SSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYS 442
+ G F QPTV NVT+ M I EEIFGPV ++KFK +D+VIKRAN+T GL+ ++
Sbjct: 376 GNKG-YFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFT 434
Query: 443 QNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
++I + L G V VN + PFGG K SG G+E +YG +YTE+K + V
Sbjct: 435 KDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTV 494
>Hs21361176 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 315 bits (806), Expect = 1e-85
Identities = 182/480 (37%), Positives = 277/480 (56%), Gaps = 12/480 (2%)
Query: 29 TKAFINGKWTET--DDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF---GTFRQT 83
TK FIN +W ++ KF V NP+T + + +V D +KA++ A AF +R
Sbjct: 21 TKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTM 80
Query: 84 NVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDS-LGEIVYSAMFFKWFAEEAPRI 142
+ ER ++L + +L+ ++ LA + ++ GK Y ++ L ++ ++ A A +I
Sbjct: 81 DASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKI 140
Query: 143 YGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHET 202
G IP + + +T +P+GV G + PWNFP M+ K+ P ++ GNT V+KPA +T
Sbjct: 141 QGRTIP--IDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQT 198
Query: 203 PLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQ 262
PL+AL + + ++AG P GV NI+P + G + H + K+ FTGST++G+L+
Sbjct: 199 PLTALHVASLIKEAGFPPGVVNIVP-GYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEA 257
Query: 263 SSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLY 322
+ K N+K+ ++ELGG +P IV DADLD A++ F GQ CI A+RIFV E +Y
Sbjct: 258 AGKS-NLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIY 316
Query: 323 DEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRA 382
DEF +R V++ K + LG+ GVT GP I + DK+ L++ K +GA + GG
Sbjct: 317 DEFVRRSVERAKK-YILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPW 375
Query: 383 SSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYS 442
+ G F QPTV NVT+ M I EEIFGPV ++KFK +D+VIKRAN+T GL+ ++
Sbjct: 376 GNKG-YFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFT 434
Query: 443 QNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
++I + L G V VN + PFGG K SG G+E +YG +YTE+K + V
Sbjct: 435 KDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTV 494
>SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 313 bits (802), Expect = 4e-85
Identities = 179/481 (37%), Positives = 274/481 (56%), Gaps = 11/481 (2%)
Query: 25 YLIQTKAFINGKWTET--DDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGT--- 79
Y+ FIN + ++ + V +PST I EV + D + A+++A AF T
Sbjct: 19 YIQPVGLFINNQHVDSVHGGRVKVYSPSTEKLICEVADADEEDVDIAVKVARAAFQTDAP 78
Query: 80 FRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEA 139
+R+ + +R + L + + + +N + LA I TL+NGK + G++ +A F+++ A
Sbjct: 79 WRKFSSAQRGRCLSRLADCIEQNLEYLASIETLDNGKSITLARGDVQAAADCFRYYGGWA 138
Query: 140 PRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPA 199
+ YG I + + + +T +P+GV G + PWNFP M A K+AP +A GNT ++K A
Sbjct: 139 DKDYGQTIETDIK--RFAYTRHEPIGVCGQIIPWNFPFLMCAWKIAPAVACGNTIILKTA 196
Query: 200 HETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLL 259
TPLSAL L + G P GV N+L + G + H + K+ FTGST +G+++
Sbjct: 197 ELTPLSALCLTKFVPECGFPPGVINVL-SGDGRRCGNAISSHMDIDKVAFTGSTGVGRMV 255
Query: 260 MGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHE 319
M +++ N+KK ++ELGG +P IVF DADLD A F SGQ C +R++V E
Sbjct: 256 M-RAAASSNLKKVTLELGGKSPNIVFNDADLDSAAVWTNYGIFYNSGQVCCAGSRVYVQE 314
Query: 320 DLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGG 379
D+YDEF KR+V K KT K+GD F + G + + +++ S ++ GA + IGG
Sbjct: 315 DVYDEFIKRMVAKA-KTLKVGDPFAEDTFQGAQVSKQQYERIVSYIESGIAHGAKLEIGG 373
Query: 380 SRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGY 439
R +LG F +PT+L NVTE M + EEIFGPV +IKFK ++E I+R N++ GLA
Sbjct: 374 KRHGNLG-YFVEPTILSNVTEDMAVGKEEIFGPVLAVIKFKTIEEAIRRGNNSTYGLAAG 432
Query: 440 FYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKA 499
++ NI+ + L G V VN + +PFGG K SG+G+E YG+ +YT+ KA
Sbjct: 433 VHTNNITNAIKVSNALEAGTVWVNCYNLLHHQIPFGGYKESGIGRELGSYGLTNYTQTKA 492
Query: 500 I 500
+
Sbjct: 493 V 493
>7297513 [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 313 bits (802), Expect = 4e-85
Identities = 177/483 (36%), Positives = 282/483 (57%), Gaps = 12/483 (2%)
Query: 26 LIQTKAFINGKW--TETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF---GTF 80
++ T FIN +W +++ F NP+T + I E+ D + A++ A +AF +
Sbjct: 37 ILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPW 96
Query: 81 RQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMF-FKWFAEEA 139
R+ + ER ++L + +LM ++ LA + TL+NGKPY S + +A+ ++FA A
Sbjct: 97 RRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWA 156
Query: 140 PRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPA 199
+ +G IP + D +T +P+GV G + PWNFP M+A KL P +ATGNT V+KPA
Sbjct: 157 DKNHGKTIP--MDGDFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPA 214
Query: 200 HETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLL 259
+T L+AL + + ++AG P GV N++P T+ G + H V K+ FTGST +G+L+
Sbjct: 215 EQTSLTALYIAQLVKEAGFPEGVVNVVPGFGTA--GAALANHCDVDKVAFTGSTDVGKLI 272
Query: 260 MGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHE 319
+S N+K+ ++ELGG +P I+ D D+D A++ F GQ C +R FV +
Sbjct: 273 Q-LASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVED 331
Query: 320 DLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGG 379
+YDEF +R ++ K +G+ F GP ++++ ++K+ +++ K +GA ++ GG
Sbjct: 332 KIYDEFVERSAERAKKR-TVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGG 390
Query: 380 SRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGY 439
SR L F QPTV +V + M I EEIFGPV LI+FK +DEVI+RAN+++ GLA
Sbjct: 391 SRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAA 450
Query: 440 FYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKA 499
+++++ L G V VNT + PFGG K SG G+E +Y + +YTE+K+
Sbjct: 451 VFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKS 510
Query: 500 IIV 502
+IV
Sbjct: 511 VIV 513
>CE23852 [C] KOG2450 Aldehyde dehydrogenase
Length = 537
Score = 311 bits (796), Expect = 2e-84
Identities = 174/477 (36%), Positives = 275/477 (57%), Gaps = 12/477 (2%)
Query: 32 FINGKWTETDD--KFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF---GTFRQTNVR 86
FIN ++ + F NP+ G + +V D + A+E A AF +R+ +
Sbjct: 60 FINNEFVDAKSGKTFEFVNPANGKLLAKVAEGNRDDVDIAVEAAKKAFKIGSEWRRMDAS 119
Query: 87 ERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLG-EIVYSAMFFKWFAEEAPRIYGD 145
R +L+ + +LM ++ LA + +L+NGKPYK++ ++ S F+++A A + +G
Sbjct: 120 HRGVLLNRLADLMERDRVILASLESLDNGKPYKEAYNIDLPISIKTFRYYAGYADKNHGK 179
Query: 146 IIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLS 205
IP V D +T +P+GV G + PWNFP M A KLAP +A GNT V+K A +TPLS
Sbjct: 180 TIP--VGGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLS 237
Query: 206 ALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSK 265
AL + + ++A P GV NI+P T + GE + H V K+ FTGST++G+ +M +++
Sbjct: 238 ALHVASLIKEAQFPEGVVNIIPGRGT-DAGEAIASHMDVDKVAFTGSTEVGKTIMKAAAE 296
Query: 266 GKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEF 325
N+KK ++ELGG +P IVF DADL+ A+ F GQ C +R FV +YDEF
Sbjct: 297 S-NVKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEF 355
Query: 326 SKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSL 385
+ + ++KT +GD F + T GP I + ++ + ++ K +GA ++ GG +
Sbjct: 356 VAKAKELVEKTV-IGDPFDENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGGVKHGDQ 414
Query: 386 GPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNI 445
G F +PT+ NV + M I EEIFGPV +I+F ++E+I++AN+T GLA + ++
Sbjct: 415 G-YFVKPTIFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTIYGLAAGVVTNDL 473
Query: 446 STIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
+ A + G V VN ++ +PA PFGG K SG+G+E +YG+ YTE+K + +
Sbjct: 474 NKALQVANTIRAGSVWVNCYDVFDPAAPFGGFKQSGIGRELGEYGLAAYTEVKTVTI 530
>YER073w [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 306 bits (784), Expect = 5e-83
Identities = 179/478 (37%), Positives = 279/478 (57%), Gaps = 10/478 (2%)
Query: 29 TKAFINGKWTETDDK--FAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGT-FRQTNV 85
T FING++ + K F V NPS + I V D ++A+ A AF T +
Sbjct: 44 TGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFETKWSIVEP 103
Query: 86 RERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGD 145
RA+ L N+ +L+ ++++ LA I +++NGK + G++ + + + A +IYG+
Sbjct: 104 EVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCARGDVALVSKYLRSCGGWADKIYGN 163
Query: 146 IIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLS 205
+I + + ++I++PLGV G + PWNFP M + K+ P +ATGNT V+KPA TPLS
Sbjct: 164 VIDTG--KNHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLS 221
Query: 206 ALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSK 265
AL + ++AG+PAGV NILP + +GE + H VKKI FTGST G+ +M ++
Sbjct: 222 ALFASQLCQEAGIPAGVVNILPGSGRV-VGERLSAHPDVKKIAFTGSTATGRHIMKVAAD 280
Query: 266 GKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEF 325
+KK ++ELGG +P IVF DADLD+A+ I F SG+ C +RI++ + +Y+E
Sbjct: 281 --TVKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEV 338
Query: 326 SKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSL 385
++L D + + K+GD F + V G DK + K+ V AK++GA ++ GG+R S
Sbjct: 339 LQKLKDYTE-SLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGARHGSK 397
Query: 386 GPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNI 445
G F +PTV +V M I EE+FGP+ + KF VDEVI AND+ GLA ++ +I
Sbjct: 398 G-YFVKPTVFADVKGDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDI 456
Query: 446 STIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIVA 503
+ D ++++ G V +NT VPFGG SG+G+E + + +YT+ K++ +A
Sbjct: 457 NKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSVRIA 514
>Hs11436533 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 303 bits (777), Expect = 3e-82
Identities = 176/477 (36%), Positives = 272/477 (56%), Gaps = 12/477 (2%)
Query: 32 FINGKWTETDDK--FAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF---GTFRQTNVR 86
FIN +W + + F NPSTG+ I +V D +KA++ A AF +R+ +
Sbjct: 40 FINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDAS 99
Query: 87 ERAQILDNIYNLMLENKQDLAKILTLENGKPYKDS-LGEIVYSAMFFKWFAEEAPRIYGD 145
R ++L+ + +L+ ++ LA + TL+NGKPY S L ++ +++A A + +G
Sbjct: 100 HRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGK 159
Query: 146 IIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLS 205
IP + D +T +P+GV G + PWNFP M A KL P +ATGN V+K A +TPL+
Sbjct: 160 TIP--IDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLT 217
Query: 206 ALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSK 265
AL + + ++AG P GV NI+P G + HE V K+ FTGST+IG+++ ++
Sbjct: 218 ALYVANLIKEAGFPPGVVNIVP-GFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ-VAAG 275
Query: 266 GKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEF 325
N+K+ ++ELGG +P I+ DAD+D A++ F GQ C +R FV ED+YDEF
Sbjct: 276 SSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEF 335
Query: 326 SKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSL 385
+R V + K+ +G+ F GP + + K+ + K +GA +L GG A+
Sbjct: 336 VERSVARA-KSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADR 394
Query: 386 GPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNI 445
G F QPTV G+V + M I EEIFGPV ++KFK ++EV+ RAN++ GLA +++++
Sbjct: 395 G-YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDL 453
Query: 446 STIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
++ L G V VN ++ PFGG K SG G+E +YG+ YTE+K + V
Sbjct: 454 DKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTV 510
>YOR374w [C] KOG2450 Aldehyde dehydrogenase
Length = 519
Score = 303 bits (775), Expect = 5e-82
Identities = 181/481 (37%), Positives = 270/481 (55%), Gaps = 11/481 (2%)
Query: 24 DYLIQTKAFINGKW--TETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF--GT 79
+Y T FIN K+ ++ + F V NPST + I + D +A++ A AF G+
Sbjct: 40 EYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGS 99
Query: 80 FRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEA 139
+ + +R + L + L+ ++K +A I TL+NGK S G++ + K A A
Sbjct: 100 WNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSSRGDVDLVINYLKSSAGFA 159
Query: 140 PRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPA 199
+I G +I + + +T RQPLGV G + PWNFP M A K+AP + TGNT V+K A
Sbjct: 160 DKIDGRMIDTGRTHFS--YTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTA 217
Query: 200 HETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLL 259
TPLSAL + +AG+P GV NI+ + +GE + H +KK+ FTGST G+ +
Sbjct: 218 ESTPLSALYVSKYIPQAGIPPGVINIV-SGFGKIVGEAITNHPKIKKVAFTGSTATGRHI 276
Query: 260 MGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHE 319
++ G +KK ++ELGG +P IVF DA+L +A+ II + SG+ C +R++V E
Sbjct: 277 YQSAAAG--LKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEE 334
Query: 320 DLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGG 379
+YD+F + ++ K+GD F + G ++K+ V K +GA ++ GG
Sbjct: 335 SIYDKFIEEF-KAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGG 393
Query: 380 SRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGY 439
R S G F +PTV G+V E M I EEIFGPV + KFK DEVI AND++ GLA
Sbjct: 394 ERLGSKG-YFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAG 452
Query: 440 FYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKA 499
++ NI+T A+++N G V +NT AVPFGG SGLG+E S + +Y ++KA
Sbjct: 453 IHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKA 512
Query: 500 I 500
+
Sbjct: 513 V 513
>Hs4502033 [C] KOG2450 Aldehyde dehydrogenase
Length = 516
Score = 296 bits (757), Expect = 6e-80
Identities = 175/477 (36%), Positives = 268/477 (55%), Gaps = 12/477 (2%)
Query: 32 FINGKWTETDDK--FAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF---GTFRQTNVR 86
FIN +W + + F NPSTG+ I +V D +KA E AF +R+ +
Sbjct: 39 FINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAREGRPGAFQLGSPWRRMDAS 98
Query: 87 ERAQILDNIYNLMLENKQDLAKILTLENGKPYKDS-LGEIVYSAMFFKWFAEEAPRIYGD 145
++L+ + +L+ ++ LA + TL+NGKPY S L ++ +++A A + +G
Sbjct: 99 HSGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGK 158
Query: 146 IIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLS 205
IP + D +T +P+GV G + PWNFP M A KL P +ATGN V+K A +TPL+
Sbjct: 159 TIP--IDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLT 216
Query: 206 ALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSK 265
AL + + ++AG P GV NI+P G + HE V K+ FTGST+IG+++ ++
Sbjct: 217 ALYVANLIKEAGFPPGVVNIVP-GFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ-VAAG 274
Query: 266 GKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEF 325
N+K+ ++ELGG +P I+ DAD+D A++ F GQ C +R FV ED+YDEF
Sbjct: 275 SSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEF 334
Query: 326 SKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSL 385
R V + K+ +G+ F GP + + K+ + K +GA +L GG A+
Sbjct: 335 VVRSVARA-KSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADR 393
Query: 386 GPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNI 445
G F QPTV G+V + M I EEIFGPV ++KFK ++EV+ RAN++ GLA +++++
Sbjct: 394 G-YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDL 452
Query: 446 STIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
++ L G V VN ++ PFGG K SG G+E +YG+ YTE+K + V
Sbjct: 453 DKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTV 509
>SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 294 bits (753), Expect = 2e-79
Identities = 157/470 (33%), Positives = 268/470 (56%), Gaps = 6/470 (1%)
Query: 32 FINGKWTETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQI 91
+ING+W ++ + + +PS + I +V G + + A++ A +AF T+++ E+ ++
Sbjct: 24 YINGEWHKSAETWETVDPSIEEVIAKVYLAGEKEIDYAVKSAKEAFKTWKKVPGSEKGEL 83
Query: 92 LDNIYNLMLENKQDLAKILTLENGKPY-KDSLGEIVYSAMFFKWFAEEAPRIYGDIIPSA 150
L + L ++ LA I +++GKP ++ G++ + ++ A A +IYG +IP+
Sbjct: 84 LMKLAELTEKHADTLAAIEAMDSGKPLVSNARGDVDGTIALLRYCAGWADKIYGQVIPTG 143
Query: 151 VSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALG 210
++ + R P+GV G + PWN+P M K+AP +A GN +IK A TPLS L
Sbjct: 144 --PEKLAYAKRTPIGVCGQIVPWNYPLNMAGWKIAPALAAGNCIIIKSAETTPLSLLYFA 201
Query: 211 VIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNIK 270
+ E+AG P GV NI+ T G Y+ +H + KI FTGSTK+G ++ Q N+K
Sbjct: 202 TLVEEAGFPKGVVNIISGLGTVA-GSYMAKHPGIDKIAFTGSTKVGVIV--QQLAASNLK 258
Query: 271 KFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLV 330
++E GG +P++VF+DADLD+A+ SGQ C +RI+V + +YD+F +
Sbjct: 259 AVTLECGGKSPFLVFEDADLDQAVKWAALGIMYNSGQICTSNSRIYVQDSVYDKFIELFK 318
Query: 331 DKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGPLFY 390
+ + + +G F D GP+++ +++ + ++ K +GA +++G F
Sbjct: 319 KHVIQDYIVGMPFDDNTVVGPVVNKTQYNRIKNYIEQGKKEGAKLVLGDEPLPLKQGYFI 378
Query: 391 QPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNISTIFD 450
PT+ + +E+M I EEIFGPV + KFK DE I++AN+T GLA +++++
Sbjct: 379 SPTIFADCSENMTIVKEEIFGPVVAISKFKTEDEAIEKANNTTYGLAAMCFTKDLERAHR 438
Query: 451 AAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
+++L GMV +N+ E S+ PFGG+K SG+G E GI+ YT++KA+
Sbjct: 439 VSDELEAGMVFINSTENSDIQAPFGGIKMSGIGNELGSNGIEMYTQIKAV 488
>Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 294 bits (752), Expect = 2e-79
Identities = 175/478 (36%), Positives = 282/478 (58%), Gaps = 13/478 (2%)
Query: 32 FINGKWTETDD-KFAVT-NPSTGDTIREVTNCGVSDFNKAIEIAHDAF--GTFRQTNVRE 87
FI G++ + + K + T NP+ G I +V+ V+D +KA+ A DAF G + + + R+
Sbjct: 425 FIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWGKISARD 484
Query: 88 RAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIV-YSAMFFKWFAEEAPRIYGDI 146
R +++ + +LM +++++LA I L+ G Y +L V S F++FA +I G
Sbjct: 485 RGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGST 544
Query: 147 IPSAVSSDQKIFTI--RQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPL 204
IP + + T+ ++P+GV GI+ PWN+P M++ K A +A GNT VIKPA TPL
Sbjct: 545 IPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPL 604
Query: 205 SALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSS 264
+AL + KAG+P GV N+LP S +G+ + +H V+KI FTGST++G+ +M +S
Sbjct: 605 TALKFAELTLKAGIPKGVVNVLP-GSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIM-KSC 662
Query: 265 KGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDE 324
N+KK S+ELGG +P I+F D DL++A+ + F G+ CI A R+FV + ++DE
Sbjct: 663 AISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDE 722
Query: 325 FSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASS 384
F +R+V+++ K K+G+ HGP H + K+ Q +GA ++ GG++
Sbjct: 723 FVRRVVEEVRK-MKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPR 781
Query: 385 LGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFK--DVDEVIKRANDTDVGLAGYFYS 442
G F++PTV +V + M I EE FGPV + +F D+D V+ RAN T+ GLA ++
Sbjct: 782 PG-FFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFT 840
Query: 443 QNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
++I+ ++KL G V VNT ++ A PFGG K SG GK+ + +++Y +K +
Sbjct: 841 RDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTV 898
>HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 293 bits (749), Expect = 5e-79
Identities = 174/478 (36%), Positives = 282/478 (58%), Gaps = 13/478 (2%)
Query: 32 FINGKWTETDD-KFAVT-NPSTGDTIREVTNCGVSDFNKAIEIAHDAF--GTFRQTNVRE 87
FI G++ + + K + T NP+ G I +V+ V+D +KA+ A AF G + + + R+
Sbjct: 425 FIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKGAFENGRWGKISARD 484
Query: 88 RAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIV-YSAMFFKWFAEEAPRIYGDI 146
R +++ + +LM +++++LA I L+ G Y +L V S F++FA +I G
Sbjct: 485 RGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGST 544
Query: 147 IPSAVSSDQKIFTI--RQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPL 204
IP + + T+ ++P+GV GI+ PWN+P M++ K A +A GNT VIKPA TPL
Sbjct: 545 IPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPL 604
Query: 205 SALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSS 264
+AL + KAG+P GV N+LP S +G+ + +H V+KI FTGST++G+ +M +S
Sbjct: 605 TALKFAELTLKAGIPKGVVNVLP-GSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIM-KSC 662
Query: 265 KGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDE 324
N+KK S+ELGG +P+I+F D DL++A+ + F G+ CI A R+FV + ++DE
Sbjct: 663 AISNVKKVSLELGGESPFIIFADCDLNKAVQMGMSSVFFSKGENCIAAGRLFVEDSIHDE 722
Query: 325 FSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASS 384
F +R+V+++ K K+G+ HGP H + K+ Q +GA ++ GG++
Sbjct: 723 FVRRVVEEVRK-MKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPR 781
Query: 385 LGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFK--DVDEVIKRANDTDVGLAGYFYS 442
G F++PTV +V + M I EE FGPV + +F D+D V+ RAN T+ GLA ++
Sbjct: 782 PG-FFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFT 840
Query: 443 QNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
++I+ ++KL G V VNT ++ A PFGG K SG GK+ + +++Y +K +
Sbjct: 841 RDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTV 898
>CE29393 [C] KOG2450 Aldehyde dehydrogenase
Length = 510
Score = 293 bits (749), Expect = 5e-79
Identities = 168/481 (34%), Positives = 271/481 (55%), Gaps = 14/481 (2%)
Query: 29 TKAFINGKWT--ETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF---GTFRQT 83
T FIN ++ ++ F NP+ G + +V +D N A++ A +AF +R+
Sbjct: 30 TGIFINNEFVPAKSGKTFETINPANGKVLAQVAEGDKTDVNIAVKAAQNAFRIGSEWRRM 89
Query: 84 NVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLG-EIVYSAMFFKWFAEEAPRI 142
+ +R +L+ + +LM ++ LA + +L+NGKPY + ++ S + A +
Sbjct: 90 DASQRGVLLNRLADLMERDRVILASLESLDNGKPYAVAYNADLPLSIKTLRLLRRMADKN 149
Query: 143 YGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHET 202
+G IP + D +T +P+GV G + PWNFP M A KL P +A GNT V+K A +T
Sbjct: 150 HGKTIP--IEGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALAMGNTVVMKVAEQT 207
Query: 203 PLSALALGVIAEKAGLPAGVCNILPT-NHTSEIGEYVCEHELVKKITFTGSTKIGQLLMG 261
PLSAL + + ++AG P GV NI+P HT+ G+ + H V K+ FTGST++G+L+M
Sbjct: 208 PLSALHVAALTKEAGFPDGVVNIIPGYGHTA--GQAISSHMDVDKVAFTGSTEVGRLVMK 265
Query: 262 QSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDL 321
+++ N+KK ++ELGG +P I+F DADL+ ++ F GQ C +R FV +
Sbjct: 266 AAAES-NVKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCCCAGSRTFVEGKI 324
Query: 322 YDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSR 381
YD+F R + +K +GD F T GP + K ++ + + K GA ++ GG++
Sbjct: 325 YDDFVARSKELAEKAV-IGDPFDLKTTQGPQVDGKQVETILKYIAAGKKDGAQLVTGGAK 383
Query: 382 ASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFY 441
G F +PT+ NV + M I EEIFGPV +I+F ++E++++AN+T GLA
Sbjct: 384 HGDQGH-FVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKANNTIYGLAAGVM 442
Query: 442 SQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAII 501
+++I A G V VN ++ + A PFGG K SG+G+E +YG++ YTE+K +
Sbjct: 443 TKDIDKALHIANATRAGSVWVNCYDVFDAAAPFGGFKQSGIGRELGEYGLEAYTEVKTVT 502
Query: 502 V 502
+
Sbjct: 503 I 503
>YPL061w [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 281 bits (718), Expect = 2e-75
Identities = 167/477 (35%), Positives = 266/477 (55%), Gaps = 11/477 (2%)
Query: 29 TKAFINGKWTETDD--KFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGT--FRQTN 84
T FIN K+ + D + V +PST +T+ EV++ D AIE A AF + +
Sbjct: 26 TGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDTEWATQD 85
Query: 85 VRERAQILDNIYNLMLENKQDL-AKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIY 143
RER ++L + + LE++ DL + I L+NGK + G++ + + A A ++
Sbjct: 86 PRERGRLLSKLAD-ELESQIDLVSSIEALDNGKTLALARGDVTIAINCLRDAAAYADKVN 144
Query: 144 GDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETP 203
G I + FT +P+GV G + PWNFP M+A K+AP +A GN C++KPA TP
Sbjct: 145 GRTINTG--DGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTP 202
Query: 204 LSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQS 263
L+AL + +K G+PAGV NI+P + +G + ++K+ FTGST++G+ + S
Sbjct: 203 LNALYFASLCKKVGIPAGVVNIVPGPGRT-VGAALTNDPRIRKLAFTGSTEVGKSVAVDS 261
Query: 264 SKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYD 323
S+ N+KK ++ELGG + ++VF DA++ + L ++ F+ +GQ C +RI+V E +YD
Sbjct: 262 SES-NLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYD 320
Query: 324 EFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRAS 383
E ++ K+G+ F G + + + D + + + K +GA +L GG +
Sbjct: 321 ELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVG 380
Query: 384 SLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQ 443
G F +PTV +V E M I EEIFGPV + KFK ++E ++ AN ++ GL ++
Sbjct: 381 DKG-YFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETE 439
Query: 444 NISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
++ST A+ L G V +NT + VPFGGVK SG G+E + YTE+KA+
Sbjct: 440 SLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAV 496
>YMR170c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 274 bits (701), Expect = 2e-73
Identities = 160/484 (33%), Positives = 265/484 (54%), Gaps = 24/484 (4%)
Query: 32 FINGKWTETDDKFAV--TNPSTGDTIREVTNCGVSDFNKAIEIAHDAF-GTFRQTNVRER 88
FIN ++ + D + NP+TG+ I D +KA++ A AF + +T+ +R
Sbjct: 24 FINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQR 83
Query: 89 AQILDNIYNLMLENKQDLAKILTLENGKPY-KDSLGEIVYSAMFFKWFAEEAPRI-YGDI 146
L N+ L+ E + LA + TL+ GKPY ++ G++ ++FA A + G
Sbjct: 84 GIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGAT 143
Query: 147 IPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSA 206
IP ++ ++ +T++ P GV+ + PWN+P AM KL +A GNT +IKPA T LS
Sbjct: 144 IP--LTFNKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSL 201
Query: 207 LALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKG 266
L + +KAG P GV NI+P + S +G+ + H + KI+FTGSTK+G ++ ++S
Sbjct: 202 LYFATLIKKAGFPPGVVNIVP-GYGSLVGQALASHMDIDKISFTGSTKVGGFVL-EASGQ 259
Query: 267 KNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFS 326
N+K ++E GG +P +VF+DADLD+A+D I F SGQ C +R++V +YD+F
Sbjct: 260 SNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFV 319
Query: 327 KRLVDKIDKTFKLG---DGFQDGVTHGPLIHDKSIDKVASLVQDAKTKG-------ADVL 376
++ + K + + D F + GP+I D++ S ++ K + ++
Sbjct: 320 EKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFP 379
Query: 377 IGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGL 436
IGG++ F PT+ +V ++ + +EIFGPV + KF + D+ +K ANDT GL
Sbjct: 380 IGGAKG-----YFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGL 434
Query: 437 AGYFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTE 496
A +++++ A + G V +N+ + VPFGG K SG+G+E + G+D Y +
Sbjct: 435 ASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQ 494
Query: 497 LKAI 500
KA+
Sbjct: 495 TKAV 498
>At3g48170 [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 273 bits (699), Expect = 3e-73
Identities = 170/480 (35%), Positives = 261/480 (53%), Gaps = 16/480 (3%)
Query: 32 FINGKWTET--DDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGT-----FRQTN 84
FI G+WTE V NP+T D I + D A+E A AF + +
Sbjct: 11 FIGGQWTEPVLRKTLPVVNPATEDIIGYIPAATSEDVELAVEAARKAFTRNNGKDWARAT 70
Query: 85 VRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYG 144
RA+ L I ++E K +LA + ++ GKP ++ ++ A F+++A+ A +
Sbjct: 71 GAVRAKYLRAIAAKVIERKSELANLEAIDCGKPLDEAAWDMDDVAGCFEYYADLAEGLDA 130
Query: 145 -DIIPSAVSSDQ-KIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHET 202
P ++ D K + +++P+GV+G++TPWN+P M K+AP +A G T ++KP+
Sbjct: 131 KQKTPLSLPMDTFKGYILKEPIGVVGMITPWNYPLLMAVWKVAPSLAAGCTAILKPSELA 190
Query: 203 PLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQ 262
L+ L L I + GLP GV NIL T +E G + H V KI FTGST G +M
Sbjct: 191 SLTCLELADICREVGLPPGVLNIL-TGLGTEAGAPLASHPHVDKIVFTGSTTTGSSIM-- 247
Query: 263 SSKGKNIKKFSMELGGNAPYIVFKDADLDRALDG-IIGCKFRQSGQTCICANRIFVHEDL 321
+S K +K S+ELGG +P IVF D D+D+A++ + GC F +GQ C +R+ VHE +
Sbjct: 248 TSAAKLVKPVSLELGGKSPIIVFDDVDIDKAVEWTMFGC-FWTNGQICSATSRLLVHERI 306
Query: 322 YDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSR 381
DEF +LV K K K+ D F++G GP++ ++V V +A+ +GA VL GG R
Sbjct: 307 ADEFLDKLV-KWTKNIKISDPFEEGCRLGPVVSKGQYERVLKFVSNARNEGATVLCGGVR 365
Query: 382 ASSLGP-LFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYF 440
L F +P ++ NVT SM+I+ EE+FGP + F DE I+ AND+ GLAG
Sbjct: 366 PEHLKKGYFVEPAIVSNVTTSMEIWREEVFGPALCVKTFSTEDEAIQLANDSQYGLAGAV 425
Query: 441 YSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
S ++ ++ G+V VN + P+GG K SG G+E ++G+++Y +K +
Sbjct: 426 LSNDLERCDRVSKAFQAGIVWVNCSQPCFCQAPWGGTKRSGFGRELGEWGLENYLSVKQV 485
>CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 887
Score = 271 bits (692), Expect = 2e-72
Identities = 169/480 (35%), Positives = 267/480 (55%), Gaps = 34/480 (7%)
Query: 32 FINGKWTETDD--KFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF--GTFRQTNVRE 87
FI+GK+ + D F NP+T I E+ V+D ++A+ A AF G +RQ + RE
Sbjct: 431 FIDGKFVGSSDGRTFKTINPATEKPICELPLATVADVDRAVRAAKKAFERGEWRQMSARE 490
Query: 88 RAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIV-YSAMFFKWFAEEAPRIYGDI 146
R + L + LM E+K++LA + +L+ G Y +L V S +++FA +I G
Sbjct: 491 RGKRLYKLAELMEEHKEELATLESLDAGAVYTLALKTHVGMSIDVWRYFAGWCDKIQGKT 550
Query: 147 IPSAVSSDQK--IFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPL 204
IP + + K T+R+P+GV+G++TPWN+P M++ K+A +A +I+ +
Sbjct: 551 IPISNARPNKNLCLTLREPIGVVGLITPWNYPLMMLSWKMAACLAAAKIKLIEIS----- 605
Query: 205 SALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSS 264
GV NI+ T S +G + H V+KI FTGST+IG +M +
Sbjct: 606 ----------------GVINIV-TGSGSLVGNRLTAHPDVRKIGFTGSTEIGATVMESCA 648
Query: 265 KGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDE 324
K NIKK S+ELGG +P I+F DADL++A+ G F G+ CI A R+F+ + ++D+
Sbjct: 649 KS-NIKKVSLELGGKSPLIIFADADLEKAVKQACGAVFFNKGENCIAAGRVFIAKSIHDD 707
Query: 325 FSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASS 384
F K+LV++ K +++GD HGP H ++K+ V+ A GA V +GG R
Sbjct: 708 FVKKLVEEA-KQYQIGDPLDRSTAHGPQNHLAHLNKLVEYVEKAVAGGAKVEVGGKRLER 766
Query: 385 LGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKF--KDVDEVIKRANDTDVGLAGYFYS 442
G L++ PT+L N+ + EE FGP+ + F D+++V++RANDT+ GLA ++
Sbjct: 767 EG-LYFPPTILSNIDDENFAASEESFGPIMCVSSFDDDDIEDVLRRANDTEFGLAAGVFT 825
Query: 443 QNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
++ S AE L+ G V VNT + ++ A PFGG K SG GK+ + +++Y K I +
Sbjct: 826 RDSSKSLRVAEALHAGTVFVNTYQKTDVAAPFGGFKQSGFGKDMGEEALNEYLVTKTITI 885
>YMR169c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 270 bits (690), Expect = 4e-72
Identities = 157/488 (32%), Positives = 266/488 (54%), Gaps = 28/488 (5%)
Query: 32 FINGKWTETDDKFAV--TNPSTGDTIREVTNCGVSDFNKAIEIAHDAF-GTFRQTNVRER 88
FIN ++ + D + NP+TG+ I D +KA++ A AF + +T+ +R
Sbjct: 24 FINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQR 83
Query: 89 AQILDNIYNLMLENKQDLAKILTLENGKPY----KDSLGEIVYSAMFFKWFAEEAPRIYG 144
L N+ L+ E + LA + TL+ GKP+ K L +I+ ++ ++ G
Sbjct: 84 GIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNM--G 141
Query: 145 DIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPL 204
+ IP ++ ++ +T++ P GV+ + PWN+P AM RK+ +A GNT +IKPA T L
Sbjct: 142 ETIP--LTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSL 199
Query: 205 SALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSS 264
S L + +KAG P GV N++P + S +G+ + H + KI+FTGSTK+G ++ ++S
Sbjct: 200 SLLYFATLIKKAGFPPGVVNVIP-GYGSVVGKALGTHMDIDKISFTGSTKVGGSVL-EAS 257
Query: 265 KGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDE 324
N+K ++E GG +P +VF+DADLD+A++ + F SGQ C +R++V +YD+
Sbjct: 258 GQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDK 317
Query: 325 FSKRLVDKIDKTFKLG---DGFQDGVTHGPLIHDKSIDKVASLVQDAKTKG-------AD 374
F ++ + K + + D F + GP+I D++ S ++ K + ++
Sbjct: 318 FVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSE 377
Query: 375 VLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDV 434
IGG++ F PT+ +V E+ + +EIFGPV + KF + D+ +K ANDT
Sbjct: 378 FPIGGAKG-----YFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCY 432
Query: 435 GLAGYFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDY 494
GLA +++++ A + G V +N E VPFGG K SG+G+E G+D+Y
Sbjct: 433 GLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNY 492
Query: 495 TELKAIIV 502
++K++ V
Sbjct: 493 LQIKSVHV 500
>Hs12007648 [C] KOG2450 Aldehyde dehydrogenase
Length = 487
Score = 264 bits (675), Expect = 2e-70
Identities = 160/484 (33%), Positives = 262/484 (54%), Gaps = 12/484 (2%)
Query: 26 LIQTKAFINGKWTETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNV 85
L+ + FI+GK+ +PSTG+ V N G + A++ A +AF ++ +
Sbjct: 7 LLMLENFIDGKFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSP 66
Query: 86 RERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLG-EIVYSAMFFKWFAEEAPRIYG 144
+ER+++L+ + +L+ ++ ++ A+ + + GK + +I S F++FA +
Sbjct: 67 QERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTS 126
Query: 145 DIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPL 204
+ +T+R P+GV G+++PWN P ++ K+AP +A GNT + KP+ T +
Sbjct: 127 ECTQMDHLGCMH-YTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSV 185
Query: 205 SALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSS 264
+A L + +KAG+P GV NI+ +GE + H V I+FTGS + + S+
Sbjct: 186 TAWMLCKLLDKAGVPPGVVNIV-FGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSA 244
Query: 265 KGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDE 324
+ KK S+ELGG P I+F+DA+LD + + F G+ C+C +RIFV + +Y E
Sbjct: 245 P--HCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSE 302
Query: 325 FSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGS---- 380
F KR V+ K +K+G V+ G LI ++KV S V+ A +GA + G
Sbjct: 303 FLKRFVEATRK-WKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKL 361
Query: 381 --RASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAG 438
A + F PTV+ ++ + EEIFGPV ++ F +EVI+RAN+ GLA
Sbjct: 362 SLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAA 421
Query: 439 YFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELK 498
+S N+ + A+KL G+V N I E +PFGG+K+SG+G+EG+K D +TE+K
Sbjct: 422 TVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIK 481
Query: 499 AIIV 502
I V
Sbjct: 482 TITV 485
>CE07233 [C] KOG2450 Aldehyde dehydrogenase
Length = 687
Score = 259 bits (661), Expect = 9e-69
Identities = 160/491 (32%), Positives = 261/491 (52%), Gaps = 11/491 (2%)
Query: 17 MSSKIENDYLIQTKAFINGKWTE--TDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAH 74
++S E L + F+ G E +D KF V P +G + + ++ A
Sbjct: 194 LNSLTETKLLELSSHFVAGNHVEFPSDRKFEVIEPRSGKPMATWHYATRDQVDLTVKEAK 253
Query: 75 DAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKW 134
A + +++ ER++IL +L+ + D+A + NGKP ++ +++ F +
Sbjct: 254 KAQKQWAKSSWMERSEILKKTGDLLKTHCNDIAYWECISNGKPIAEAKADVLSCVDTFYF 313
Query: 135 FAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTC 194
++ A + G +P + + + +T R P+GV+ + WN+P + K AP +A GN
Sbjct: 314 YSGIASDLLGQHVP--LDASRYAYTRRLPVGVVAAIGAWNYPIQTCSWKTAPALACGNAV 371
Query: 195 VIKPAHETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTK 254
+ KP+ +P++AL L I + AGLP GV N++ + +E + + H+ V K++FTGS
Sbjct: 372 IYKPSPLSPVTALILAEILKSAGLPDGVFNVIQGD--AETAQDLIHHDGVSKVSFTGSIP 429
Query: 255 IGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANR 314
G+ +M ++ +NIK ++ELGG + IVF DAD+D A+ + F GQ C A++
Sbjct: 430 TGKKIM-KACADRNIKPVTLELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASK 488
Query: 315 IFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGAD 374
+ VH+ + EF+K+LVD K K+GD ++ G I + +KV + A +GA
Sbjct: 489 VLVHKSVLKEFTKKLVDHTQK-MKIGDPLKEDTQVGSHISAEHRNKVEGYISTAIAEGAT 547
Query: 375 VLIGGSRASSLG---PLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRAND 431
L GG R + G + P +L +T M ++ EEIFG V +I F DE IK AND
Sbjct: 548 KLCGGDRVAVHGLENGFYLSPCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIAND 607
Query: 432 TDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGI 491
TD+GLA ++++S + +E+LN G V VNT P VPFGGV SG G+E +
Sbjct: 608 TDMGLAAGLVTKDLSRSYRVSEQLNAGNVYVNTYNDVSPLVPFGGVGESGFGRENGTAVL 667
Query: 492 DDYTELKAIIV 502
+ YT LK++ V
Sbjct: 668 EHYTHLKSVFV 678
>Hs4502047 [C] KOG2450 Aldehyde dehydrogenase
Length = 493
Score = 258 bits (659), Expect = 1e-68
Identities = 155/459 (33%), Positives = 247/459 (53%), Gaps = 12/459 (2%)
Query: 49 PSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAK 108
P+TG I T G + N A++ A AF + Q + ER +IL ++ E + ++A
Sbjct: 33 PATGRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAARIIREREDEIAT 92
Query: 109 ILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIG 168
+ + NGK ++ +I S +++A A + G+ I S +T R+PLGV
Sbjct: 93 MECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFG--YTRREPLGVCV 150
Query: 169 ILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPT 228
+ WN+P + + K AP +A GN V KP+ TP+SAL L I +AG+P G+ N++
Sbjct: 151 GIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLFNVVQG 210
Query: 229 NHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDA 288
+ G+++C+H V K++FTGS G +M S+KG IK ++ELGG +P I+F D
Sbjct: 211 GAAT--GQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKG--IKPVTLELGGKSPLIIFSDC 266
Query: 289 DLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVT 348
D++ A+ G + F GQ C R+FV +++ D+F++ +V + + K+GD +
Sbjct: 267 DMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQR-IKIGDPLLEDTR 325
Query: 349 HGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGP-----LFYQPTVLGNVTESMD 403
GPLI+ +++V V+ AK +GA VL GG P + +P VL N + M
Sbjct: 326 MGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMT 385
Query: 404 IFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVN 463
EEIFGPV ++ F EV++RANDT GLA ++++I +L G +N
Sbjct: 386 CVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFIN 445
Query: 464 TGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
+S +PFGG K SG G+E + I+ Y++LK + V
Sbjct: 446 NYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCV 484
>CE24573 [C] KOG2450 Aldehyde dehydrogenase
Length = 574
Score = 256 bits (654), Expect = 6e-68
Identities = 156/478 (32%), Positives = 252/478 (52%), Gaps = 10/478 (2%)
Query: 32 FINGKWT--ETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERA 89
F+NGK T E+ + F V P G + + ++ ++ A DA + +T +R
Sbjct: 90 FLNGKRTTIESTETFDVIEPRIGQVVAKCPKATADIVDQYVKAAADAQSAWGETTALDRG 149
Query: 90 QILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIY-GDIIP 148
++L + +L+ E+ +++A NGKP ++ +I SA F +F A + GD +
Sbjct: 150 KVLHKVADLIREHAEEIAIWEVKTNGKPIYEARCDIASSADTFDFFGGIATAVLQGDSLE 209
Query: 149 SAVSSDQKI-FTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSAL 207
Q+I +T R+P GV+G + WN+P K+AP +A GN V KP+ P S +
Sbjct: 210 LPGGPSQRIAYTRREPYGVVGCIGAWNYPFQTCVWKVAPALAAGNAVVYKPSPFAPASPV 269
Query: 208 ALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGK 267
LG I AG+P GV N++ E G +CEH LV K++FTGS G+ + Q++ K
Sbjct: 270 LLGEILTAAGVPKGVYNVIQGEQ--EAGVALCEHNLVAKVSFTGSVASGEAVQRQAAT-K 326
Query: 268 NIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSK 327
N+K ++ELGG + I+F D+D+ A+ + F GQ C A R+FV + + F++
Sbjct: 327 NVKPVTLELGGKSEIIIFDDSDVKSAVASAMLANFLNQGQVCTNATRVFVQKGILASFTE 386
Query: 328 RLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGP 387
+V + + K+GD + G I++ + ++ V+ AK +G VL GG R G
Sbjct: 387 AIVQEANDKLKVGDPLLEDTRVGANINEGHLQRILGYVESAKQEGGVVLRGGVRVHPTGV 446
Query: 388 ---LFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQN 444
+++P ++ +++ EEIFG V ++ F+ +EVI RAN+T GLA +S N
Sbjct: 447 EGGAYFEPAIITGLSDEARAVREEIFGAVMLILPFETEEEVIARANNTTYGLAAGVFSGN 506
Query: 445 ISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
++ A +L G V +NT +E VPFGG KNSG G+E + +T+ KAI V
Sbjct: 507 LARGHRVAARLQAGTVFINTYNDTEVNVPFGGFKNSGHGRENCIDTLRAHTQTKAIYV 564
>SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 251 bits (640), Expect = 2e-66
Identities = 161/480 (33%), Positives = 248/480 (51%), Gaps = 11/480 (2%)
Query: 28 QTKAFINGKWTETDDKFA----VTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF--GTFR 81
+ FI+GK+ + A + NP+T + I N D + A+E A++ F G +
Sbjct: 20 ENSLFIDGKFVSPIEPAAKPIPLINPATEEIIGTCANASAKDVDSAVENAYNTFRSGIWA 79
Query: 82 QTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPR 141
+ ++R +L I +M E ++ LA I T+ GKP +L +I A F+++AE A
Sbjct: 80 KWPGKQRGLVLRKIAKMMREKRELLAGIDTINCGKPTPYALFDIDSCADMFEYYAEVAET 139
Query: 142 IYGDI-IPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAH 200
+ +P + F R P GVIG++TPWNFP M KL P IA+GN V+KP+
Sbjct: 140 DNPTVKVPLPNNPGFCAFEKRFPRGVIGVITPWNFPLKMALWKLVPAIASGNCVVLKPSE 199
Query: 201 ETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLM 260
P S L +I ++AGLP GV N++ E G + H + + FTGS G+ +M
Sbjct: 200 LAPWSCLEFALICKEAGLPDGVLNVI-IGSGKESGAALSCHPKIAYLAFTGSLATGKKIM 258
Query: 261 GQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHED 320
+++ NI ++ELGG +P I+ +DADL A+ F G+ C A+R+ VHE
Sbjct: 259 HAAAE--NIVPLTLELGGKSPLIICEDADLSLAIPSAAFAIFFNQGEACTAASRLIVHES 316
Query: 321 LYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGS 380
+ DE LV + +K +G+G VT GP++ +K+ S +Q A +G ++GG
Sbjct: 317 VADEVLGGLVSEANKLI-IGNGLDPQVTLGPVVSKTQFEKIVSYIQSAINEGCKCVVGGL 375
Query: 381 RASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYF 440
S F PTV NV I+ EEIFGPV + F +E ++ AND++ GL
Sbjct: 376 PRSEQKGYFIPPTVFTNVQTHNKIWREEIFGPVLAVKTFHTNEEALELANDSEYGLGSGV 435
Query: 441 YSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
+S N T+ + + GM +N + +P+ G K+SGLG SK+G ++Y LK I
Sbjct: 436 FSTNPKTLEFFSNNIEAGMCSLNNYHVVTHELPWIGWKHSGLGVGLSKHGYNEYMRLKQI 495
>7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 816
Score = 240 bits (613), Expect = 3e-63
Identities = 131/357 (36%), Positives = 214/357 (59%), Gaps = 9/357 (2%)
Query: 27 IQTKAFINGKWTETDDK--FAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF-GTFRQT 83
+ T+ FING++ + + + + NP+ + + +V +D +KA+ AH AF G++RQ
Sbjct: 427 VPTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFYGSWRQI 486
Query: 84 NVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIV-YSAMFFKWFAEEAPRI 142
R+R Q++ N+ +LM NK++LA I ++++G Y +L V S +++FA +I
Sbjct: 487 TPRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKI 546
Query: 143 YGDIIPSAVSSDQKI--FTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAH 200
G+ IP + + FT ++P+GV G++TPWN+P M++ K+A IA GNTC+IKPA
Sbjct: 547 QGNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQ 606
Query: 201 ETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLM 260
PL+AL + +AG P GV N+LP S+ G+ V +HELV+K+ FTGST IG+ +M
Sbjct: 607 TCPLTALKFAELTVRAGFPPGVINVLP-GKGSDAGQAVADHELVRKLGFTGSTPIGKHIM 665
Query: 261 GQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHED 320
+S N+KK S+ELGG +P I+F D D+D+A+ + F G+ CI A R+FV +
Sbjct: 666 -KSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDR 724
Query: 321 LYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLI 377
++DEF +R++ + +T +GD HGP H DK+ + +GA +++
Sbjct: 725 IHDEFIRRVLKDL-RTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVV 780
>At1g74920 [C] KOG2450 Aldehyde dehydrogenase
Length = 481
Score = 237 bits (604), Expect = 3e-62
Identities = 159/485 (32%), Positives = 249/485 (50%), Gaps = 46/485 (9%)
Query: 32 FINGKWTET--DDKFAVTNPSTG------DTIREVTNCGVSDFNKAIEIAHDAFGTFRQT 83
FI+G+W E + + NP+T D I ++ D + A+ A A +
Sbjct: 11 FIDGEWREPILKKRIPIVNPATEEDLYVLDEIGDIPAATTEDVDVAVNAARRALSRNKGK 70
Query: 84 NVRE-----RAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEE 138
+ + RA+ L I + E K DLAK+ L+ GKP +++ ++ A F+++A+
Sbjct: 71 DWAKAPGAVRAKYLRAIAAKVNERKTDLAKLEALDCGKPLDEAVWDMDDVAGCFEFYADL 130
Query: 139 APRIYG-DIIPSAVSSDQ-KIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVI 196
A + P ++ + K + ++QPLGV+G++TPWN+P M K+AP +A G T ++
Sbjct: 131 AEGLDAKQKAPVSLPMESFKSYVLKQPLGVVGLITPWNYPLLMAVWKVAPSLAAGCTAIL 190
Query: 197 KPAHETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIG 256
KP+ ++ L L I + GLP GV N+L T SE G + H V KI FTGS G
Sbjct: 191 KPSELASVTCLELADICREVGLPPGVLNVL-TGFGSEAGAPLASHPGVDKIAFTGSFATG 249
Query: 257 QLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALD-GIIGCKFRQSGQTCICANRI 315
+M ++ + +K SMELGG +P IVF D DLD+A + + GC F +GQ C +R+
Sbjct: 250 SKVM--TAAAQLVKPVSMELGGKSPLIVFDDVDLDKAAEWALFGC-FWTNGQICSATSRL 306
Query: 316 FVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADV 375
VHE + EF ++LV K K K+ D ++G GP++ +KG +
Sbjct: 307 LVHESIASEFIEKLV-KWSKNIKISDPMEEGCRLGPVV----------------SKGQHL 349
Query: 376 LIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVG 435
G F +PT++ +VT SM I+ EE+FGPV + F DE I+ AND+ G
Sbjct: 350 EKG---------FFIEPTIITDVTTSMQIWREEVFGPVLCVKTFASEDEAIELANDSHYG 400
Query: 436 LAGYFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYT 495
L S + +E G+V +N + P+GGVK SG G+E ++G+D+Y
Sbjct: 401 LGAAVISNDTERCDRISEAFEAGIVWINCSQPCFTQAPWGGVKRSGFGRELGEWGLDNYL 460
Query: 496 ELKAI 500
+K +
Sbjct: 461 SVKQV 465
>CE06980 [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 224 bits (570), Expect = 3e-58
Identities = 148/476 (31%), Positives = 245/476 (51%), Gaps = 11/476 (2%)
Query: 32 FINGKWTETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQI 91
FI ++ ++ NPSTG ++ + + ++A+E A +AF T+++T V++R+ +
Sbjct: 31 FIGNEFARSEKLMDSVNPSTGKPWIKIPDGTAREVDQAVEAAKEAFKTWKKTTVQQRSAL 90
Query: 92 LDNIYNLMLENKQDLAKILTLENGKPYK-DSLGEIVYSAMFFKWFAEEAP-RIYGDIIPS 149
L+ + NL+ E D+A + + + GKP + +I F+ FA A + I
Sbjct: 91 LNKVANLIEEFNDDIAILESRDQGKPIGLAKVMDIPRCVQNFRDFANAALYSLSTSTILE 150
Query: 150 AVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALAL 209
+ + P+GV G+++PWN P +++ KLAP + GNT V KP+ T ++A L
Sbjct: 151 QPTGKFVNYVKNDPVGVAGLISPWNLPLYLLSFKLAPALVAGNTVVCKPSEMTSVTAWVL 210
Query: 210 GVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNI 269
+ G P GV N++ G+ + +H V I+FTGST IG+ + Q K
Sbjct: 211 MHAFKLVGFPPGVVNMV-IGEGKSAGQRLVDHVDVPLISFTGSTVIGKKI--QEDGAKLN 267
Query: 270 KKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRL 329
KK S+E+GG P IV+ + + I F G+ C+C +R+FV + ++ +F K
Sbjct: 268 KKVSLEMGGKNPGIVYSNYRKSD-IASIARSSFLNQGEICLCTSRLFVQKPIFADFVKSY 326
Query: 330 VDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLG--- 386
V++ K F +GD V G + +KV S ++ AK +GAD+L GG G
Sbjct: 327 VEEAKK-FTVGDPTTQ-VQIGAMNSKVHYEKVKSYIELAKKEGADILCGGVTTIQNGCEN 384
Query: 387 PLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNIS 446
F PTV+ + ++ + +EIFGPV + F +EVI+RAN T GL+ +S +
Sbjct: 385 GYFITPTVIVGLHDASKVMTDEIFGPVVCITPFDTAEEVIERANSTPYGLSATVWSSDSD 444
Query: 447 TIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
+ + A +L G V NT + ++PFGG K SG G+EG + Y++ K + V
Sbjct: 445 ELLNTANELRAGTVWCNTWLARDLSMPFGGCKQSGNGREGLHDSLHFYSDAKTVCV 500
>Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 535
Score = 214 bits (544), Expect = 3e-55
Identities = 144/482 (29%), Positives = 243/482 (49%), Gaps = 21/482 (4%)
Query: 30 KAFINGKWTET--DDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRE 87
K FI GK+ E+ D + NP+T + I V ++ + AI AF + T+V
Sbjct: 41 KLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAWADTSVLS 100
Query: 88 RAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDII 147
R Q+L L+ EN +++AK++TLE GK D+ G++ + + G+ +
Sbjct: 101 RQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETM 160
Query: 148 PSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPV-IATGNTCVIKPAHETPLSA 206
PS ++ D +++ R PLGV + P+NFP AMI + P+ + GNT ++KP+ P +
Sbjct: 161 PS-ITKDMDLYSYRLPLGVCAGIAPFNFP-AMIPLWMFPMAMVCGNTFLMKPSERVPGAT 218
Query: 207 LALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKG 266
+ L + + +G P G NI+ H E ++C+H +K I+F GS K G+ + + S
Sbjct: 219 MLLAKLLQDSGAPDGTLNIIHGQH--EAVNFICDHPDIKAISFVGSNKAGEYIFERGS-- 274
Query: 267 KNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFS 326
++ K+ +G +V DA+ + L+ ++G F +GQ C+ + L E
Sbjct: 275 RHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAV----LVGEAK 330
Query: 327 KRLVDKID--KTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASS 384
K L + ++ K ++ G Q G GPLI ++ ++V +L+ +GA +L+ G +
Sbjct: 331 KWLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKV 390
Query: 385 LG---PLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFY 441
G F PT++ NV +M + EEIFGPV +++ + +DE I+ N+ G +
Sbjct: 391 KGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIF 450
Query: 442 SQNISTIFDAAEKLNVGMVGVNTG-EISEPAVPFGGVKNSGLGKEG--SKYGIDDYTELK 498
+ N +T A ++VG VGVN + P F G ++S G K GI YT+LK
Sbjct: 451 TTNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLK 510
Query: 499 AI 500
I
Sbjct: 511 TI 512
>At2g24270 [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 211 bits (538), Expect = 2e-54
Identities = 149/482 (30%), Positives = 241/482 (49%), Gaps = 21/482 (4%)
Query: 30 KAFINGKW--TETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRE 87
K + +G+W + + A+ NP+T T +V C + N +E+A A ++ +T + +
Sbjct: 17 KYYADGEWKTSSSGKSVAIMNPATRKTQYKVQACTQEEVNAVMELAKSAQKSWAKTPLWK 76
Query: 88 RAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGD-- 145
RA++L ++ +NK +A+ L E KP KDS+ E+V S + AEE RI G+
Sbjct: 77 RAELLHKAAAILKDNKAPMAESLVKEIAKPAKDSVTEVVRSGDLISYCAEEGVRILGEGK 136
Query: 146 --IIPSAVSSDQKIF--TIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHE 201
+ S +D+ + T + PLGV+ + P+N+P + K+AP + GN+ V+KP +
Sbjct: 137 FLLSDSFPGNDRTKYCLTSKIPLGVVLAIPPFNYPVNLAVSKIAPALIAGNSLVLKPPTQ 196
Query: 202 TPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMG 261
+S L + AG P G+ + + T SEIG+++ H V I+FTG G +
Sbjct: 197 GAVSCLHMVHCFHLAGFPKGLISCI-TGKGSEIGDFLTMHPAVNCISFTG----GDTGIS 251
Query: 262 QSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDL 321
S K I MELGG IV DADLD II F SGQ C + V E +
Sbjct: 252 ISKKAGMI-PLQMELGGKDACIVLDDADLDLVASNIIKGGFSYSGQRCTAVKVVLVMESV 310
Query: 322 YDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSR 381
DE +++ K+ K +T ++ + S + + LV DAK KGA R
Sbjct: 311 ADELVEKVKAKVAKLTVGPPEENSDIT--AVVSESSANFIEGLVMDAKEKGATFCQEYKR 368
Query: 382 ASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFY 441
+L P +L NV M I +EE FGPV P+++ V+E I N ++ GL G +
Sbjct: 369 EGNL----IWPLLLDNVRPDMRIAWEEPFGPVVPVLRINSVEEGINHCNASNFGLQGCVF 424
Query: 442 SQNISTIFDAAEKLNVGMVGVNTGEISEP-AVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
+++I+ ++ + G V +N+ P PF G+K+SG+G +G I+ T++K
Sbjct: 425 TKDINKAILISDAMETGTVQINSAPARGPDHFPFQGLKDSGIGSQGVTNSINLMTKVKTT 484
Query: 501 IV 502
++
Sbjct: 485 VI 486
>CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 523
Score = 199 bits (506), Expect = 8e-51
Identities = 144/481 (29%), Positives = 247/481 (50%), Gaps = 19/481 (3%)
Query: 30 KAFINGKWTE--TDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRE 87
K +I+G+ E T D +TNP+T + I V N ++ A++ A +AF T++ T+
Sbjct: 31 KLWIDGQAVESKTTDFVELTNPATNEVIAMVPNATQAEMQAAVDSAKNAFNTWKNTSPLT 90
Query: 88 RAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDII 147
R Q + + L+ + + LA+ +T+E GK D+ G++ + + G+ +
Sbjct: 91 RQQCMFKLQALIKRDMKKLAESITIEQGKTLPDAEGDVSRGLQVVEHACSVPSLMMGETL 150
Query: 148 PSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPV-IATGNTCVIKPAHETPLSA 206
P+ VS D + R PLGV + P+NFP AMI + PV +ATGNT VIKP+ + P +A
Sbjct: 151 PN-VSRDMDTHSYRIPLGVTAGICPFNFP-AMIPLWMFPVALATGNTMVIKPSEQDPGAA 208
Query: 207 LALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKG 266
L +A++AG+P G NI+ H++ ++C++ +K I+F G G+ + + +
Sbjct: 209 QLLVELAKEAGVPDGCVNIIHGQHSAV--NFICDNPDIKAISFVGGDAAGKHIYERGA-- 264
Query: 267 KNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCIC-ANRIFVHEDLYDEF 325
KN K+ +G ++ DA+ ++ L+ + F +GQ C+ + V E +
Sbjct: 265 KNGKRVQSNMGAKNHGVIMADANKEQTLNQLTAAAFGAAGQRCMALTTAVLVGE--ARAW 322
Query: 326 SKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSL 385
LV+K K K+ G++ GPLI +S +V L++ AK +GA V + GS +
Sbjct: 323 LPELVEKA-KNLKVNAGWKPDTDIGPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVP 381
Query: 386 G---PLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYS 442
G F PT+L V +M + EEIFGPV +++ ++++E I+ N+ G ++
Sbjct: 382 GFENGNFVGPTILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPYGNGTAIFT 441
Query: 443 QNISTIFDAAEKLNVGMVGVNTG-EISEPAVPFGGVKNSGLGKEG--SKYGIDDYTELKA 499
N +T +++VG +G+N + P F G + S LG K GI YT+ K
Sbjct: 442 SNGATARKFTNEVDVGQIGINVPIPVPLPMFSFTGSRGSFLGDLNFYGKAGIQFYTQWKT 501
Query: 500 I 500
+
Sbjct: 502 V 502
>7293810 [C] KOG2453 Aldehyde dehydrogenase
Length = 594
Score = 189 bits (480), Expect = 8e-48
Identities = 137/478 (28%), Positives = 238/478 (49%), Gaps = 17/478 (3%)
Query: 34 NGKWTETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQILD 93
+G+W +P TG I +V V + I +A +A+ +RQ R +I+
Sbjct: 108 SGQWQGRGPSVTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVR 167
Query: 94 NIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDIIPSAVSS 153
I + + + K+ L K+++LE GK Y + GE V + +A RIY + ++ +
Sbjct: 168 QIGDELRKYKEPLGKLVSLEVGKIYSEGQGE-VQEFIDICDYAVGLSRIYSGQLINSERA 226
Query: 154 DQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALG-VI 212
D I +PLGV+G+++ +NFP+A+ A + TGN+ + K A TPL ++A ++
Sbjct: 227 DHSILEAWRPLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKIV 286
Query: 213 AE---KAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNI 269
AE + LP V +++G+ + + V ++FTGS + G+ + + +
Sbjct: 287 AEVLRRNNLPPVVTLC---QGGTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQR--RF 341
Query: 270 KKFSMELGGNAPYIVFKDADLDRALDG-IIGCKFRQSGQTCICANRIFVHEDLYDEFSKR 328
K +ELGGN I+ + A++ ALD + GC SGQ C RI VHE L+D+F K
Sbjct: 342 GKVILELGGNNALIIDESANVKMALDAALFGC-IGTSGQRCTTTRRIIVHEKLHDQFVKE 400
Query: 329 LVDKIDKTF-KLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGP 387
LV K + K+G + GP+ ++++ + + +AK+ G V GG+ G
Sbjct: 401 LVGKYKQLISKIGHQLEAQTLVGPVHTQQNVENYKAAIAEAKSLGGTVAFGGNVIQRDG- 459
Query: 388 LFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNIST 447
+ +PTV+ + + + E F P+ ++K K+VD+ I+ N+ + GL+ +++NI
Sbjct: 460 FYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLSSAIFTENIGQ 519
Query: 448 IFD--AAEKLNVGMVGVN-TGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIV 502
F A+ + G+V +N T +E FGG K +G G+E Y + I V
Sbjct: 520 AFKWIGAKGSDCGIVNINTTTNGAEIGGAFGGEKATGGGRESGSDAWKQYCKRATITV 577
>7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 552
Score = 189 bits (480), Expect = 8e-48
Identities = 136/482 (28%), Positives = 236/482 (48%), Gaps = 19/482 (3%)
Query: 29 TKAFINGKWTE--TDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVR 86
TK FI+GK+ E T++ V +P+T + V ++ A+E AF ++ ++
Sbjct: 58 TKLFIDGKFVESKTNEWIDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRSWSNQSIL 117
Query: 87 ERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDI 146
R Q++ + L+ EN +LAK +T E GK D+ G+++ + G+
Sbjct: 118 TRQQVMFKLQALIKENMGELAKNITKEQGKTLADAEGDVLRGLQVVEHCCSIPSLQMGET 177
Query: 147 IPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPV-IATGNTCVIKPAHETPLS 205
+ + V+ D +++ PLGV + P+NFP AMI + PV I TGNT ++KP+ P +
Sbjct: 178 VAN-VARDMDTYSLVLPLGVTAGVAPFNFP-AMIPLWMFPVAITTGNTMLLKPSERVPGA 235
Query: 206 ALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSK 265
+ L + +AG P GV N++ H + ++C+ +K ++F GS + G+ + ++
Sbjct: 236 TMLLMELLNEAGCPPGVVNVIHGQH--DAVNFICDAPEIKAVSFVGSDQAGKYIYERA-- 291
Query: 266 GKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCIC-ANRIFVHEDLYDE 324
GKN K+ +G I+ DA+ + L+ + G F +GQ C+ + +FV +
Sbjct: 292 GKNGKRVQSNMGAKNHGIILGDANKENTLNQLAGAAFGAAGQRCMALSTAVFVGD--AQA 349
Query: 325 FSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASS 384
+ LV++ K K+ G G GP+I S ++ L++ +GA +++ G + +
Sbjct: 350 WIPDLVERAQK-LKVNAGHVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITV 408
Query: 385 LG---PLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFY 441
G F PT+L +VT SM + EEIFGPV ++K +D+ I N G +
Sbjct: 409 PGYEDGYFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVF 468
Query: 442 SQNISTIFDAAEKLNVGMVGVNTG-EISEPAVPFGGVKNSGLGKEG--SKYGIDDYTELK 498
+ N + +++ G VGVN + P F G + S G K GI YT+ K
Sbjct: 469 TTNGAAARKFVNEIDAGQVGVNVPIPVPLPMFSFTGTRGSFRGDHHFYGKQGIKFYTQTK 528
Query: 499 AI 500
+
Sbjct: 529 TV 530
>Hs4557343 [C] KOG2453 Aldehyde dehydrogenase
Length = 511
Score = 187 bits (474), Expect = 4e-47
Identities = 131/467 (28%), Positives = 230/467 (49%), Gaps = 18/467 (3%)
Query: 28 QTKAFINGKWTETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRE 87
+ + NG W + P+ + I V V+D+ + ++ A +A+ + +
Sbjct: 22 ENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPK 81
Query: 88 RAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDII 147
R +I+ I + + E Q L +++LE GK + +GE+ + + I G I+
Sbjct: 82 RGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPIL 141
Query: 148 PSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSAL 207
PS S + P+G++GI+T +NFP A+ A + GN C+ K A T L ++
Sbjct: 142 PSE-RSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISV 200
Query: 208 ALGVIAEKA----GLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQL--LMG 261
A+ I K LP +C++ T ++IG + + E V ++FTGST++G+ LM
Sbjct: 201 AVTKIIAKVLEDNKLPGAICSL--TCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMV 258
Query: 262 QSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDL 321
Q G+++ +ELGGN I F+DADL + + +GQ C A R+F+HE +
Sbjct: 259 QERFGRSL----LELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESI 314
Query: 322 YDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSR 381
+DE RL K ++G+ + V +GPL +++ V++AK +G V+ GG
Sbjct: 315 HDEVVNRL-KKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKV 373
Query: 382 ASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFY 441
G + +PT++ + I + E F P+ + KFK+ +EV N+ GL+ +
Sbjct: 374 MDRPGN-YVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIF 432
Query: 442 SQNISTIFD--AAEKLNVGMVGVNTGEI-SEPAVPFGGVKNSGLGKE 485
++++ IF + + G+V VN +E FGG K++G G+E
Sbjct: 433 TKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRE 479
>At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 607
Score = 185 bits (470), Expect = 1e-46
Identities = 136/478 (28%), Positives = 232/478 (48%), Gaps = 19/478 (3%)
Query: 33 INGKWTETDDK--FAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQ 90
I G + E+ V NP+T + + +V +F A+ A AF +R T + R +
Sbjct: 118 IGGSFVESQSSSFIDVINPATQEVVSKVPLTTNEEFKAAVSAAKQAFPLWRNTPITTRQR 177
Query: 91 ILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDIIPSA 150
++ L+ +N LA +T E GK KDS G+I + A G+ +P+
Sbjct: 178 VMLKFQELIRKNMDKLAMNITTEQGKTLKDSHGDIFRGLEVVEHACGMATLQMGEYLPN- 236
Query: 151 VSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIAT-GNTCVIKPAHETPLSALAL 209
VS+ ++IR+PLGV + P+NFP AMI + PV T GNT ++KP+ + P +++ L
Sbjct: 237 VSNGVDTYSIREPLGVCAGICPFNFP-AMIPLWMFPVAVTCGNTFILKPSEKDPGASVIL 295
Query: 210 GVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQ-SSKGKN 268
+A +AGLP GV NI+ + T++ +C+ E ++ ++F GS G + + ++KGK
Sbjct: 296 AELAMEAGLPDGVLNIV--HGTNDTVNAICDDEDIRAVSFVGSNTAGMHIYARAAAKGKR 353
Query: 269 IKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKR 328
I+ +G +V DA++D L+ ++ F +GQ C+ + + D + +
Sbjct: 354 IQS---NMGAKNHGLVLPDANIDATLNALLAAGFGAAGQRCMALSTVVFVGDA-KSWEDK 409
Query: 329 LVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLG-- 386
LV++ K K+ G + GP+I ++ +++ L+Q GA +L+ G G
Sbjct: 410 LVERA-KALKVTCGSEPDADLGPVISKQAKERICRLIQSGVDDGAKLLLDGRDIVVPGYE 468
Query: 387 -PLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNI 445
F PT+L VT M+ + EEIFGPV ++ DE I N G ++ +
Sbjct: 469 KGNFIGPTILSGVTPDMECYKEEIFGPVLVCMQANSFDEAISIINKNKYGNGAAIFTSSG 528
Query: 446 STIFDAAEKLNVGMVGVNTG-EISEPAVPFGGVKNSGLGKEG--SKYGIDDYTELKAI 500
+ + G +G+N + P F G K S G K G+D +T++K +
Sbjct: 529 AAARKFQMDIEAGQIGINVPIPVPLPFFSFTGNKASFAGDLNFYGKAGVDFFTQIKTV 586
>At1g54100 [C] KOG2453 Aldehyde dehydrogenase
Length = 508
Score = 180 bits (456), Expect = 5e-45
Identities = 122/462 (26%), Positives = 218/462 (46%), Gaps = 15/462 (3%)
Query: 31 AFINGKWTETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQ 90
+++ GKW + NP+ I +V + D+ + ++ +A + Q +R
Sbjct: 23 SYVAGKWQANGPLVSTLNPANNQPIAQVVEASLEDYEQGLKACEEAAKIWMQVTAPKRGD 82
Query: 91 ILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDIIPSA 150
I+ I + + L ++L+LE GK + +GE+ + + ++ G +IPS
Sbjct: 83 IVRQIGDALRSKLDYLGRLLSLEMGKILAEGIGEVQEVIDMCDFAVGLSRQLNGSVIPSE 142
Query: 151 VSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALAL- 209
+ + + PLG++G++T +NFP A++ + GN V K A TPL +A+
Sbjct: 143 -RPNHMMLEMWNPLGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMT 201
Query: 210 ---GVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKG 266
+ EK LP + + +EIGE + + + ++FTGS+++G ++ Q +
Sbjct: 202 KLVAEVLEKNNLPGAIFTAMCGG--AEIGEAIAKDTRIPLVSFTGSSRVGSMV--QQTVN 257
Query: 267 KNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFS 326
K +EL GN IV DAD+ A ++ +GQ C R+ +HE +YD+
Sbjct: 258 ARSGKTLLELSGNNAIIVMDDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVYDKVL 317
Query: 327 KRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLG 386
++L+ K K+G+ + G GPL +S ++ K++G +L GG G
Sbjct: 318 EQLLTSY-KQVKIGNPLEKGTLLGPLHTPESKKNFEKGIEVIKSQGGKILTGGKAVEGEG 376
Query: 387 PLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNIS 446
F +PT++ ++ + EE+F PV ++KFK E + N GL+ +++N
Sbjct: 377 N-FVEPTII-EISADAAVVKEELFAPVLYVLKFKSFGEAVAINNSVPQGLSSSIFTRNPE 434
Query: 447 TIFDAAEKL--NVGMVGVN-TGEISEPAVPFGGVKNSGLGKE 485
IF L + G+V VN +E FGG K +G G+E
Sbjct: 435 NIFRWIGPLGSDCGIVNVNIPTNGAEIGGAFGGEKATGGGRE 476
>At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 578
Score = 177 bits (450), Expect = 3e-44
Identities = 132/466 (28%), Positives = 226/466 (48%), Gaps = 27/466 (5%)
Query: 35 GKWTETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQILDN 94
G+ ++D K P+T + ++ + + ++ A T+ Q++ + R Q L
Sbjct: 57 GRSQQSDKKVQCYEPATMKYLGYFPALSPTEVEERVTLSRKAQKTWAQSSFKLRRQFLRI 116
Query: 95 IYNLMLENKQDLAKILTLENGKPYKD-SLGEIVYSAMFFKWFAEEAPRIYGDIIPSAVSS 153
+ ++E+++ + ++ + + GK D SLGEI+ + W E R + P + SS
Sbjct: 117 LLKYIIEHQELICEVSSRDTGKTMVDASLGEIMTTCEKITWLLSEGERW---LKPESRSS 173
Query: 154 DQ----KIFTIR-QPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALA 208
+ K+ + PLGVIG + PWN+P I + + +GN VIK + S
Sbjct: 174 GRAMLHKVSRVEFHPLGVIGAIVPWNYPFHNIFNPMLAAVFSGNGIVIKVSEHASWSGCF 233
Query: 209 LGVIAEKA----GLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSS 264
I + A G P + +++ +E GE + V K+ F GST +G+++M ++
Sbjct: 234 YFRIIQAALAAVGAPENLVDVI--TGFAETGEALVSS--VDKMIFVGSTAVGKMIMRNAA 289
Query: 265 KGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDE 324
+ + ++ELGG +I+ +DAD+ + + SGQ C A R +VH+D+Y
Sbjct: 290 E--TLTPVTLELGGKDAFIICEDADVSHVAQVAVRGTLQSSGQNCAGAERFYVHKDIYTA 347
Query: 325 FSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASS 384
F + V KI K+ G G + + + + SLV DA KGA++ + GS
Sbjct: 348 FIGQ-VTKIVKSVSAGPPLTGRYDMGAICLQEHSEHLQSLVNDALDKGAEIAVRGS-FGH 405
Query: 385 LGP----LFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYF 440
LG ++ PTVL NV +M I EE FGP+ P+++F +EVIK AND+ L
Sbjct: 406 LGEDAVDQYFPPTVLINVNHNMKIMKEEAFGPIMPIMQFSTDEEVIKLANDSRYALGCAV 465
Query: 441 YSQNISTIFDAAEKLNVGMVGVN--TGEISEPAVPFGGVKNSGLGK 484
+S + A ++ G+ +N ++PFGGVK+SG G+
Sbjct: 466 FSGSKHRAKQIASQIQCGVAAINDFASNYMCQSLPFGGVKDSGFGR 511
>CE01232 [C] KOG2453 Aldehyde dehydrogenase
Length = 514
Score = 177 bits (449), Expect = 3e-44
Identities = 125/460 (27%), Positives = 221/460 (47%), Gaps = 14/460 (3%)
Query: 34 NGKWTETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQILD 93
+GKW + P+ I V N V D+ AI A A+ + + R +I+
Sbjct: 29 HGKWAASGQVVQSFAPANNSPIANVQNGNVQDYEIAISEAKKAYNDWCEVPAPRRGEIVR 88
Query: 94 NIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDIIPSAVSS 153
I + + Q+L K+++LE GK + +GE+ + + + G I PS
Sbjct: 89 QIGDKLRTQLQNLGKLVSLEMGKISAEGVGEVQEYVDICDYATGLSRSLEGKIFPSE-RP 147
Query: 154 DQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIA 213
+ PLGV+G+++ +NFP A+ A + TGN+ V KPA TPL+A+A+ +
Sbjct: 148 GHALLEQWNPLGVVGVISAFNFPCAVYGWNNALALVTGNSVVWKPAPSTPLTAIAVTKLV 207
Query: 214 EKA----GLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNI 269
E+ + +C+++ ++G+ + + + V ++FTGS++IG+ ++GQ + +
Sbjct: 208 EEVLVANNVNPALCSLVCGE--GDVGQALVKDKRVNLVSFTGSSEIGK-IVGQQVQAR-F 263
Query: 270 KKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRL 329
K +ELGGN IV +DADL+ + + +GQ C R+ VH+ +YD+ +RL
Sbjct: 264 GKLLLELGGNNAIIVNEDADLNMVVPATVFAAVGTAGQRCTTTRRLIVHDKVYDQVLERL 323
Query: 330 VDKIDK-TFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGPL 388
+ ++G GPL + +++ K + V +A G + GG G
Sbjct: 324 KKAYAQFESRIGCPLDSNTIIGPLHNQQAVGKYKASVAEAVASGGKIEYGGKVLERDGN- 382
Query: 389 FYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNISTI 448
F PT++ + + E F P+ ++KF ++E I N+ D GL+ ++ NI +
Sbjct: 383 FVLPTIVTGLKHDSPVVLRETFAPILYVLKFSTLEEAIAINNEVDQGLSSSLFTTNIQNV 442
Query: 449 FD--AAEKLNVGMVGVNTGEI-SEPAVPFGGVKNSGLGKE 485
F + + G+V VN +E FGG K +G G+E
Sbjct: 443 FKWMGPKGSDCGIVNVNIPTSGAEIGGAFGGEKETGGGRE 482
>YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G
Length = 644
Score = 172 bits (436), Expect = 1e-42
Identities = 135/490 (27%), Positives = 223/490 (44%), Gaps = 32/490 (6%)
Query: 37 WTETDDKFAVTN-PSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQILDNI 95
W + F + P+TG + + +D ++ + A A T+ ++ R ++L ++
Sbjct: 104 WNPEEPNFIQCHCPATGQYLGSFPSKTEADIDEMVSKAGKAQSTWGNSDFSRRLRVLASL 163
Query: 96 YNLMLENKQDLAKILTLENGKPYKD-SLGEIVYSAMFFKWFAEEAPRIYGDIIPSAVSSD 154
++ +L N+ +A++ ++GK D S+GEI+ + +W + R + PS
Sbjct: 164 HDYILNNQDLIARVACRDSGKTMLDASMGEILVTLEKIQWTIKHGQRA---LQPSRRPGP 220
Query: 155 QKIFT-------IR-QPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSA 206
F IR +PLGVI + WN+P + + + TGN V+K + + S+
Sbjct: 221 TNFFMKWYKGAEIRYEPLGVISSIVSWNYPFHNLLGPIIAALFTGNAIVVKCSEQVVWSS 280
Query: 207 LALGVIAEKAGLPA--------GVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQL 258
+ K L A +C LP + Y H K ITF GS +
Sbjct: 281 EFFVELIRKC-LEACDEDPDLVQLCYCLPPTENDDSANYFTSHPGFKHITFIGSQPVAHY 339
Query: 259 LMGQSSKGKNIKKFSMELGGNAPYIVFKDA-DLDRALDGIIGCKFRQSGQTCICANRIFV 317
++ K++ +ELGG +IV A +LD I+ F+ SGQ CI R+ V
Sbjct: 340 IL--KCAAKSLTPVVVELGGKDAFIVLDSAKNLDALSSIIMRGTFQSSGQNCIGIERVIV 397
Query: 318 HEDLYDEFSKRLVDKIDKT-FKLGDGFQ--DGVTHGPLIHDKSIDKVASLVQDAKTKGAD 374
++ YD+ K L D++ + G + V G +I D D++ +LV+DA KGA
Sbjct: 398 SKENYDDLVKILNDRMTANPLRQGSDIDHLENVDMGAMISDNRFDELEALVKDAVAKGAR 457
Query: 375 VLIGGSRASSLG---PLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRAND 431
+L GGSR ++QPT+L +VT M I E+FGP+ ++K K+ D ++ AN
Sbjct: 458 LLQGGSRFKHPKYPQGHYFQPTLLVDVTPEMKIAQNEVFGPILVMMKAKNTDHCVQLANS 517
Query: 432 TDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNT-GEISEPAVPFGGVKNSGLGKEGSKYG 490
GL G + +I A L G V +N +PFGG+ SG GK G + G
Sbjct: 518 APFGLGGSVFGADIKECNYVANSLQTGNVAINDFATFYVCQLPFGGINGSGYGKFGGEEG 577
Query: 491 IDDYTELKAI 500
+ K++
Sbjct: 578 LLGLCNAKSV 587
>SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 522
Score = 166 bits (420), Expect = 8e-41
Identities = 134/469 (28%), Positives = 219/469 (46%), Gaps = 28/469 (5%)
Query: 49 PSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAK 108
P G + EV SD +++I +A +A ++ T+ ER L + ++ N+ A+
Sbjct: 10 PGDGSLLGEVKLFNKSDIDQSIILAEEAQKEWKSTSFAERRNFLKALKENIIRNQDKYAE 69
Query: 109 ILTLENGKPYKDS-LGEIVYSAMFFKW-FAEEAPRIYGDIIPSAVSSDQKIFTIR-QPLG 165
I + GK D+ GEI+ + W A + P+++ + K ++ +PLG
Sbjct: 70 IACKDTGKTLVDAAFGEILVTLEKINWTLANGEQSLRPTKRPNSLLTSYKGGYVKYEPLG 129
Query: 166 VIGILTPWNFPSAMIARKLAPVIAT---GNTCVIKPAHETPLSA-----LALGVIAEKAG 217
VI L WN+P + L P+I+ GN V+K + T S + ++
Sbjct: 130 VIAALVSWNYP---LHNALGPIISALFAGNAIVVKGSELTAWSTHQYCEMVRSLLQSMGH 186
Query: 218 LPAGVCNI--LPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSME 275
P V I LP ++ +++ H +K ITF GS I +L+ +S K + +E
Sbjct: 187 SPELVQCITCLP-----DVADHLTSHSGIKHITFIGSQPIAKLVA--ASAAKQLTPLCLE 239
Query: 276 LGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDK 335
LGG P I+ D L+ L ++ F+ +GQ CI RI + +YD +L ++I
Sbjct: 240 LGGKDPCILTDDHRLEEILSIVMRGVFQSAGQNCIGIERIIALDGVYDTIITKLYNRIS- 298
Query: 336 TFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLG---PLFYQP 392
T +LG Q+ V G ++ + D + SL+QDA +KGA ++ GG R ++ P
Sbjct: 299 TMRLGMYTQNDVDMGAMVSNNRFDHLESLIQDAVSKGARLVYGGHRFQHPKYPKGNYFLP 358
Query: 393 TVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNISTIFDAA 452
T+L + T M I EE F P+A + + K + ++ AN T+ GL + ++
Sbjct: 359 TLLVDATNEMKIAQEECFAPIALVFRAKSPEHALEIANGTEFGLGASVFGRDKQLCQYFT 418
Query: 453 EKLNVGMVGVNT-GEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAI 500
+ L GMV VN G +PFGG K SG G+ G+ KAI
Sbjct: 419 DNLETGMVAVNDFGAFYLLQMPFGGCKKSGYGRFAGYEGLRGICNSKAI 467
>Hs21359829 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 156 bits (395), Expect = 6e-38
Identities = 119/451 (26%), Positives = 219/451 (48%), Gaps = 28/451 (6%)
Query: 63 VSDFNKAIEIAHDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGK-PYKDS 121
+S ++A++ A AF + R ++ R Q L+ + L+ E +Q+L L + K +
Sbjct: 1 MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY 60
Query: 122 LGEIVYSAMFFKWFAEEAPRIYGD--IIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAM 179
E+VY ++ ++ P D + + + +++ +PLGV+ ++ WN+P +
Sbjct: 61 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL 120
Query: 180 IARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPTN--HTSEIGEY 237
+ + IA GN V+KP+ + A L I + L + ++ T+E+ +
Sbjct: 121 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGVPETTELLKE 179
Query: 238 VCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGI 297
+H I +TGST +G+++M ++ K++ ++ELGG +P V K+ DLD A I
Sbjct: 180 RFDH-----ILYTGSTGVGKIIM--TAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRI 232
Query: 298 IGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFK--LGDGFQDGVTHGPLIHD 355
KF SGQTC+ + I + ++ +V+K+ K+ K G+ + +G +I
Sbjct: 233 AWGKFMNSGQTCVAPDYILCDPSIQNQ----IVEKLKKSLKEFYGEDAKKSRDYGRIISA 288
Query: 356 KSIDKVASLVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAP 415
+ +V L++ G V GG+ + PT+L +V + EEIFGPV P
Sbjct: 289 RHFQRVMGLIE-----GQKVAYGGT--GDAATRYIAPTILTDVDPQSPVMQEEIFGPVLP 341
Query: 416 LIKFKDVDEVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVN--TGEISEPAVP 473
++ + ++E I+ N + LA Y +S N I + + G V N I+ ++P
Sbjct: 342 IVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLP 401
Query: 474 FGGVKNSGLGKEGSKYGIDDYTELKAIIVAP 504
FGGV NSG+G K + ++ ++ +V P
Sbjct: 402 FGGVGNSGMGSYHGKKSFETFSHRRSCLVRP 432
>HsM4502035 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 156 bits (394), Expect = 8e-38
Identities = 119/451 (26%), Positives = 219/451 (48%), Gaps = 28/451 (6%)
Query: 63 VSDFNKAIEIAHDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGK-PYKDS 121
+S ++A++ A AF + R ++ R Q L+ + L+ E +Q+L L + K +
Sbjct: 1 MSKISEAVKRARAAFSSGRTRPLQFRFQQLEALQRLIQEQEQELVGALAADLHKNEWNAY 60
Query: 122 LGEIVYSAMFFKWFAEEAPRIYGD--IIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAM 179
E+VY ++ ++ P D + + + +++ +PLGV+ ++ WN+P +
Sbjct: 61 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL 120
Query: 180 IARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPTN--HTSEIGEY 237
+ + IA GN V+KP+ + A L I + L + ++ T+E+ +
Sbjct: 121 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGVPETTELLKE 179
Query: 238 VCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGI 297
+H I +TGST +G+++M ++ K++ ++ELGG +P V K+ DLD A I
Sbjct: 180 RFDH-----ILYTGSTGVGKIIM--TAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRI 232
Query: 298 IGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFK--LGDGFQDGVTHGPLIHD 355
KF SGQTC+ + I + ++ +V+K+ K+ K G+ + +G +I
Sbjct: 233 AWGKFMNSGQTCVAPDYILCDPSIQNQ----IVEKLKKSLKEFYGEDAKKSRDYGRIISA 288
Query: 356 KSIDKVASLVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAP 415
+ +V L++ G V GG+ + PT+L +V + EEIFGPV P
Sbjct: 289 RHFQRVMGLIE-----GQKVAYGGT--GDAATRYIAPTILTDVDPQSPVMQEEIFGPVLP 341
Query: 416 LIKFKDVDEVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVN--TGEISEPAVP 473
++ + ++E I+ N + LA Y +S N I + + G V N I+ ++P
Sbjct: 342 IVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLP 401
Query: 474 FGGVKNSGLGKEGSKYGIDDYTELKAIIVAP 504
FGGV NSG+G K + ++ ++ +V P
Sbjct: 402 FGGVGNSGMGSYHGKKSFETFSHRRSCLVRP 432
>CE27441 [C] KOG2456 Aldehyde dehydrogenase
Length = 493
Score = 149 bits (377), Expect = 7e-36
Identities = 125/451 (27%), Positives = 223/451 (48%), Gaps = 39/451 (8%)
Query: 66 FNKAIEIAHDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEI 125
F + +E F T V+ R Q L + + EN++ L++ + + + ++ + EI
Sbjct: 3 FTELVETQRKYFRTGETKPVKFRKQQLLKLKKFIEENREALSEAVWKDLRRRHEST--EI 60
Query: 126 VYSAMFFKWFAEEAPRIYGDIIPSAVSSDQKIFTI--------RQPLGVIGILTPWNFPS 177
+ M + I + P+ V +K FT + P GV+ I++PWN+P
Sbjct: 61 LEIGMTIQEIDYFLKNIDDWVKPTHV---EKTFTTALDKPVIEKDPKGVVLIISPWNYPV 117
Query: 178 AMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEY 237
+MI + P IA GNT VIKP S L+ V A L + + + + +
Sbjct: 118 SMILLPMVPAIAAGNTVVIKP------SELSENVAATFEKL---IPKYFESKYVTVVNGG 168
Query: 238 VCE-HELVKK----ITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDR 292
+ E +L+K+ I +TG + +++M ++ K++ ++ELGG P +V DAD+D
Sbjct: 169 IPETTDLLKERFDHILYTGCPPVAKIIM--TAAAKHLTPVTLELGGKCPVVVEDDADIDI 226
Query: 293 ALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPL 352
+ I K+ GQTC+ + I V+ + + + +++ + G+ + + +
Sbjct: 227 SAKRIAWGKWLNCGQTCLAPDYILVNSTVKPKLVAAIRKYVNEFY--GEDVKASKDYARM 284
Query: 353 IHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGP 412
I+ + D+++ L+ KT+GA VLIGG R L+ PTVL +V +S ++EIFGP
Sbjct: 285 INQRHFDRISGLLD--KTQGA-VLIGGER--DRADLYIPPTVL-DVEKSDPFMHDEIFGP 338
Query: 413 VAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVN--TGEISEP 470
V P+I + E ++ D + LA Y +++N + + + + G V VN I+
Sbjct: 339 VLPIITVQSFSESLEYIADGEKPLAAYIFTRNEAKVKRLLNETSSGGVTVNDVLMHITVD 398
Query: 471 AVPFGGVKNSGLGKEGSKYGIDDYTELKAII 501
+PFGGV SG+G+ KYG D +T K+++
Sbjct: 399 TLPFGGVGVSGMGRYRGKYGFDTFTHEKSVL 429
>CE13415 [C] KOG2456 Aldehyde dehydrogenase
Length = 437
Score = 144 bits (363), Expect = 3e-34
Identities = 117/450 (26%), Positives = 218/450 (48%), Gaps = 36/450 (8%)
Query: 67 NKAIEIAHDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYK------- 119
++ +E F T R + L + L+ EN+ L +++ + + ++
Sbjct: 4 HRIVEAQRAYFNTGATKPAEFRKEQLLQLKKLIEENRAALTEVVWKDLRRRHEVTEPMEL 63
Query: 120 -DSLGEIVYSAMFFKWFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSA 178
SL EI Y + K + Y + + + +D K + ++ P GV+ +++PWN+P +
Sbjct: 64 GGSLEEIAY---YLKNLDDWMKPTYVEPTVATLPTD-KPYIVKDPKGVVLVISPWNYPVS 119
Query: 179 MIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNI---LPTNHTSEIG 235
M+ + P IA GNT VIKP+ + +A+ + K P V + +P T+E+
Sbjct: 120 MVLLPMIPSIAAGNTIVIKPSELSENTAILFEKLIPKYFDPKYVTIVNGGIP--ETTELL 177
Query: 236 EYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALD 295
+ +H I +TG + +++M ++ K++ ++ELGG P +V DAD++ +
Sbjct: 178 KERFDH-----IIYTGCPPVAKIIM--AAAAKHLTPVTLELGGKCPVVVEDDADIEISAQ 230
Query: 296 GIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFK--LGDGFQDGVTHGPLI 353
I K+ GQTC+ + I V +F V I K K G ++ + +I
Sbjct: 231 RIARGKWLNCGQTCLAPDYILVSSATKPKF----VAAIQKCLKEFYGGNAKESKDYSRVI 286
Query: 354 HDKSIDKVASLVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPV 413
+ + D++++L+ ++K VL G + F PTVL +V ++ ++EIFGPV
Sbjct: 287 NQRHFDRISALLDESK---GVVLAGNEESRDRSDRFIPPTVL-DVEKTDPFMHDEIFGPV 342
Query: 414 APLIKFKDVDEVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVN--TGEISEPA 471
P+I K++ E I N + LA Y ++++ + + + G V VN ++
Sbjct: 343 LPIITVKNLCESIDFINKGEKPLAAYIFTKDEAKVQRFLNETTSGGVTVNDVIMHVAVIT 402
Query: 472 VPFGGVKNSGLGKEGSKYGIDDYTELKAII 501
+PFGGV SG+G+ K+G D +T K+++
Sbjct: 403 LPFGGVGVSGMGRYRGKFGFDTFTHEKSVL 432
>Hs4502045 [C] KOG2456 Aldehyde dehydrogenase
Length = 385
Score = 139 bits (351), Expect = 8e-33
Identities = 102/353 (28%), Positives = 176/353 (48%), Gaps = 23/353 (6%)
Query: 157 IFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKA 216
+F ++P G++ I+ PWN+P + L + GN V+KP+ +S V+AE
Sbjct: 17 VFIWKEPFGLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSE---ISQGTEKVLAEV- 72
Query: 217 GLPAGV---CNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFS 273
LP + C + E G+ + EH+L I FTGS ++G+++M ++K ++ +
Sbjct: 73 -LPQYLDQSCFAVVLGGPQETGQLL-EHKL-DYIFFTGSPRVGKIVMTAATK--HLTPVT 127
Query: 274 MELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKI 333
+ELGG P V + D + + + +GQTC+ + + ++ + L I
Sbjct: 128 LELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTI 187
Query: 334 DKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGPLFYQPT 393
+ + GD Q G +I+ K ++ +L+ + V IGG S+ + PT
Sbjct: 188 TRFY--GDDPQSSPNLGRIINQKQFQRLRALLGCGR-----VAIGGQ--SNESDRYIAPT 238
Query: 394 VLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNISTIFDAAE 453
VL +V E+ + EEIFGP+ P++ + VDE IK N + LA Y +S + + E
Sbjct: 239 VLVDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSRQVVNQMLE 298
Query: 454 KLNVGMVGVNTG--EISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIVAP 504
+ + G G N G IS +VPFGGV +SG+G+ K+ D ++ + ++AP
Sbjct: 299 RTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAP 351
>Hs4557303 [C] KOG2456 Aldehyde dehydrogenase
Length = 485
Score = 134 bits (336), Expect = 4e-31
Identities = 111/436 (25%), Positives = 206/436 (46%), Gaps = 28/436 (6%)
Query: 76 AFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMF-FKW 134
AF + R +R R Q L+ + ++ E ++D+ + + K + + V + + +
Sbjct: 11 AFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITVLGEIDF 70
Query: 135 FAEEAPR--IYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGN 192
E P + + ++ + + QPLGV+ I+ WN+P + + L IA GN
Sbjct: 71 MLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGN 130
Query: 193 TCVIKPAHETPLSALALGVIAEKAGLPAGVCNILP--TNHTSEIGEYVCEHELVKKITFT 250
+IKP+ + +A L + + L + ++ T+E+ + +H I +T
Sbjct: 131 AVIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELLKQRFDH-----IFYT 184
Query: 251 GSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCI 310
G+T +G+++M + K++ ++ELGG +P + KD DLD I K+ GQTCI
Sbjct: 185 GNTAVGKIVM--EAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCI 242
Query: 311 CANRIFVHEDLYDEFSKRLVDKIDKTFK--LGDGFQDGVTHGPLIHDKSIDKVASLVQDA 368
+ I L ++ +V KI +T K G+ ++ + +I+ + ++ SL++
Sbjct: 243 APDYILCEASLQNQ----IVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLE-- 296
Query: 369 KTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKR 428
G + GG + + PTVL +V + EEIFGP+ P++ K+VDE I
Sbjct: 297 ---GQKIAFGGETDEATR--YIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINF 351
Query: 429 ANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVN--TGEISEPAVPFGGVKNSGLGKEG 486
N+ + LA Y +S N I ++ + G V N + + PFGGV +SG+G
Sbjct: 352 INEREKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYH 411
Query: 487 SKYGIDDYTELKAIIV 502
K+ D ++ + ++
Sbjct: 412 GKHSFDTFSHQRPCLL 427
>Hs18603595 [C] KOG2456 Aldehyde dehydrogenase
Length = 508
Score = 134 bits (336), Expect = 4e-31
Identities = 111/436 (25%), Positives = 206/436 (46%), Gaps = 28/436 (6%)
Query: 76 AFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMF-FKW 134
AF + R +R R Q L+ + ++ E ++D+ + + K + + V + + +
Sbjct: 11 AFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITVLGEIDF 70
Query: 135 FAEEAPR--IYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGN 192
E P + + ++ + + QPLGV+ I+ WN+P + + L IA GN
Sbjct: 71 MLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGN 130
Query: 193 TCVIKPAHETPLSALALGVIAEKAGLPAGVCNILP--TNHTSEIGEYVCEHELVKKITFT 250
+IKP+ + +A L + + L + ++ T+E+ + +H I +T
Sbjct: 131 AVIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELLKQRFDH-----IFYT 184
Query: 251 GSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCI 310
G+T +G+++M + K++ ++ELGG +P + KD DLD I K+ GQTCI
Sbjct: 185 GNTAVGKIVM--EAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCI 242
Query: 311 CANRIFVHEDLYDEFSKRLVDKIDKTFK--LGDGFQDGVTHGPLIHDKSIDKVASLVQDA 368
+ I L ++ +V KI +T K G+ ++ + +I+ + ++ SL++
Sbjct: 243 APDYILCEASLQNQ----IVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLE-- 296
Query: 369 KTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKR 428
G + GG + + PTVL +V + EEIFGP+ P++ K+VDE I
Sbjct: 297 ---GQKIAFGGETDEATR--YIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINF 351
Query: 429 ANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVN--TGEISEPAVPFGGVKNSGLGKEG 486
N+ + LA Y +S N I ++ + G V N + + PFGGV +SG+G
Sbjct: 352 INEREKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYH 411
Query: 487 SKYGIDDYTELKAIIV 502
K+ D ++ + ++
Sbjct: 412 GKHSFDTFSHQRPCLL 427
>Hs4502043 [C] KOG2456 Aldehyde dehydrogenase
Length = 468
Score = 130 bits (327), Expect = 5e-30
Identities = 115/443 (25%), Positives = 201/443 (44%), Gaps = 40/443 (9%)
Query: 75 DAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDS--------LGEIV 126
+AF R RA L + + ENKQ L L + K +S GE+
Sbjct: 13 EAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVT 72
Query: 127 YSAMFFK-WFAEE-APRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKL 184
+ + W +E P+ + SA F ++P G++ I+ PWN+P + L
Sbjct: 73 LALRNLRAWMKDERVPKNLATQLDSA-------FIRKEPFGLVLIIAPWNYPLNLTLVPL 125
Query: 185 APVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGV---CNILPTNHTSEIGEYVCEH 241
+A GN V+KP+ +S ++AE LP V C + E G+ + EH
Sbjct: 126 VGALAAGNCVVLKPSE---ISKNVEKILAEV--LPQYVDQSCFAVVLGGPQETGQLL-EH 179
Query: 242 ELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCK 301
I FTGS ++G+++M ++ K++ ++ELGG P V + D + + +
Sbjct: 180 RF-DYIFFTGSPRVGKIVM--TAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFR 236
Query: 302 FRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKV 361
+ +GQTC+ + + ++ + L I + + GD Q G +I+ K ++
Sbjct: 237 YFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFY--GDDPQSSPNLGRIINQKQFQRL 294
Query: 362 ASLVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKD 421
+L+ + V IGG S + PTVL +V E + EEIFGP+ P++ +
Sbjct: 295 RALLGCGR-----VAIGGQSDES--DRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQS 347
Query: 422 VDEVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTG--EISEPAVPFGGVKN 479
+DE I+ N + LA Y +S + + + + G N G ++ ++PFGGV
Sbjct: 348 LDEAIEFINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGA 407
Query: 480 SGLGKEGSKYGIDDYTELKAIIV 502
SG+G+ K+ D ++ +A ++
Sbjct: 408 SGMGRYHGKFSFDTFSHHRACLL 430
>YMR110c [C] KOG2456 Aldehyde dehydrogenase
Length = 532
Score = 127 bits (318), Expect = 5e-29
Identities = 109/469 (23%), Positives = 208/469 (44%), Gaps = 59/469 (12%)
Query: 66 FNKAIEIAHDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEI 125
F K ++++H+ R+ ++ R L +Y + +++++L + YKD
Sbjct: 29 FEKQLKLSHE--NNPRKKDLEFRQLQLKKLYYAVKDHEEELIDAM-------YKDFHRNK 79
Query: 126 VYSAMFFKWFAEEAPRIYGDII-----------PSAVSSDQKIFTIRQPL------GVIG 168
+ S + E ++ DI+ P VS F + + G +
Sbjct: 80 IESVL------NETTKLMNDILHLIEILPKLIKPRRVSDSSPPFMFGKTIVEKISRGSVL 133
Query: 169 ILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNIL-- 226
I+ P+NFP + LA +A GNT V+KP+ TP +A+ + + AG P G+ ++
Sbjct: 134 IIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQG 193
Query: 227 ---PTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYI 283
T + G++ I +TGS ++G ++ +++ K++ +ELGG +P
Sbjct: 194 AIDETTRLLDCGKF-------DLIFYTGSPRVGSIVAEKAA--KSLTPCVLELGGKSPTF 244
Query: 284 V---FKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFKLG 340
+ FK +++ AL I F SGQ C+ + + VH+ +Y + K +++ +
Sbjct: 245 ITENFKASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFY--- 301
Query: 341 DGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIG--GSRASSLGPLFYQPTVLGNV 398
F + +IH+ + K + + T G+ ++ + + PT++ N+
Sbjct: 302 PSFDEQTDFTRMIHEPAYKKAVASIN--STNGSKIVPSKISINSDTEDLCLVPPTIVYNI 359
Query: 399 TESMDIFYEEIFGPVAPLIKFKDVDEVI-KRANDTDVGLAGYFYSQNISTIFDAAEKLNV 457
+ +E F PV P+I+++D+DE I K + D L Y +S + + I +L
Sbjct: 360 GWDDPLMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRS 419
Query: 458 G--MVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIVAP 504
G +VG + PFGG+ SG G G YG + ++ + I P
Sbjct: 420 GDCVVGDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTIFKQP 468
>At1g44170 [C] KOG2456 Aldehyde dehydrogenase
Length = 484
Score = 120 bits (302), Expect = 4e-27
Identities = 98/377 (25%), Positives = 176/377 (45%), Gaps = 32/377 (8%)
Query: 134 WFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNT 193
W A E + P++ + +PLGV+ +++ WN+P + + I+ GN
Sbjct: 89 WMAPEKAKTSLTTFPASAE------IVSEPLGVVLVISAWNYPFLLSIDPVIGAISAGNA 142
Query: 194 CVIKPAHETPLSALALGVIAEKAGLPAGVCNIL-PTNHTSEIGEYVCEHELVKKITFTGS 252
V+KP+ P S+ L + E+ P+ V + TS + E + KI +TGS
Sbjct: 143 VVLKPSELAPASSALLTKLLEQYLDPSAVRVVEGAVTETSALLEQKWD-----KIFYTGS 197
Query: 253 TKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLD----RALDGIIGCKFRQSGQT 308
+KIG+++M ++ K++ +ELGG +P +V D DL R + G GC +GQ
Sbjct: 198 SKIGRVIM--AAAAKHLTPVVLELGGKSPVVVDSDTDLKVTVRRIIVGKWGC---NNGQA 252
Query: 309 CICANRIFVHEDLYDEFSKRLVD--KIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQ 366
C+ + I + E++ +L+D K++ G + +++ D+++ L+
Sbjct: 253 CVSPDYILTTK----EYAPKLIDAMKLELEKFYGKNPIESKDMSRIVNSNHFDRLSKLL- 307
Query: 367 DAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVI 426
D K ++ GG + L PT+L +V I EEIFGP+ P++ +++E
Sbjct: 308 DEKEVSDKIVYGGEKDRE--NLKIAPTILLDVPLDSLIMSEEIFGPLLPILTLNNLEESF 365
Query: 427 KRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVN--TGEISEPAVPFGGVKNSGLGK 484
LA Y ++ N A ++ G + VN ++ +PFGGV SG+G
Sbjct: 366 DVIRSRPKPLAAYLFTHNKKLKERFAATVSAGGIVVNDIAVHLALHTLPFGGVGESGMGA 425
Query: 485 EGSKYGIDDYTELKAII 501
K+ D ++ KA++
Sbjct: 426 YHGKFSFDAFSHKKAVL 442
>CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 120 bits (301), Expect = 5e-27
Identities = 119/459 (25%), Positives = 205/459 (43%), Gaps = 30/459 (6%)
Query: 54 TIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQILDNIYNLML-ENKQDLAKILTL 112
T+ + T +AI++A A G + + ++ERA+IL +L + + L L
Sbjct: 90 TLAKYTYATGEQIQEAIDVALQARGAWERKPLKERAEILLRAADLAAGKYRMKLNASTML 149
Query: 113 ENGKPYK----DSLGEIVYSAMFFKWFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIG 168
GK D+ E++ F FA E P + + R G +
Sbjct: 150 GQGKNIIQAEIDAACELIDFFRFNAVFAMELEHYE----PISTKITKNTMQFRGMEGFVA 205
Query: 169 ILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPT 228
+ P+NF + AP + GN + KP++ LS + + E+AG+P G+ + LP+
Sbjct: 206 AIAPFNFTAIGGNLPTAPALM-GNVSLWKPSNTAVLSNYIIYELLEEAGMPPGILSFLPS 264
Query: 229 NHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKN----IKKFSMELGGNAPYIV 284
+ G+ + + + FTGS + + + ++ + K E GG + V
Sbjct: 265 D-GPVFGDVITASPHLSAVNFTGSVPTFKTIWRKVAENLDNYVTFPKLIGECGGKNFHFV 323
Query: 285 FKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQ 344
A +D G + SGQ C +R++ + ++ + ++ + I K KLGD
Sbjct: 324 HPSAHVDAVAAGTARSAWEYSGQKCSACSRMYAPKSIWPKILEK-ISAIHKEIKLGDVRD 382
Query: 345 DGVTHGPLIHDKSIDKVASLVQDAKT--KGADVLIGGSRASSLGPLFYQPTVLGNVTESM 402
V +I DK+ ++ + + AKT GA+V++GG G F +PT++
Sbjct: 383 GSVFLSAVIDDKAFARLKAYIDFAKTGADGANVVLGGKCDDKTG-YFIEPTLITVTDPKS 441
Query: 403 DIFYEEIFGPVAPLIKFKD--VDEVIKRAND-TDVGLAGYFYSQNISTIFDAAEKLN--V 457
+ EE+FGPV ++ ++D VDEV+ D T GL G +SQ+ ++ A + L V
Sbjct: 442 KLLTEEMFGPVVTVLVYEDSKVDEVLATVKDATPYGLTGAVFSQDKEFLYRARDVLRDAV 501
Query: 458 GMVGVN---TGEISEPAVPFGGVKNSGLGKE--GSKYGI 491
G + +N TG I PFGG + SG + G YG+
Sbjct: 502 GNMYLNDKSTGSIVGQQ-PFGGSRLSGTNDKAGGPHYGL 539
>YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 575
Score = 118 bits (296), Expect = 2e-26
Identities = 120/467 (25%), Positives = 202/467 (42%), Gaps = 36/467 (7%)
Query: 44 FAVTNPSTGDTI-REVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQILDNIYNLM-LE 101
F TNP+ + VT D A++ A DA + +R+ I +L+ +
Sbjct: 79 FPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTK 138
Query: 102 NKQDLAKILTLENGKP-YKDSLGEIVYSAMFFKWFAEEAPRIYGDIIPSAVSSDQKIFTI 160
+ D+ L GK Y+ + I + FF+++ + A +Y +
Sbjct: 139 YRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEY 198
Query: 161 RQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPA 220
R G + ++P+NF +A+ A + GNT V KP+ LS L + E+AGLP
Sbjct: 199 RPLEGFVYAVSPFNF-TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPK 257
Query: 221 GVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKG------KNIKKFSM 274
GV N +P + + + + + + FTGST + + L G+ G ++ +
Sbjct: 258 GVINFIPGDPVQVTDQVLADKDF-GALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIG 316
Query: 275 ELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEF--------- 325
E GG ++V A++ A+ I F GQ C A+R+++ E +EF
Sbjct: 317 ETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQ 376
Query: 326 SKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDA-KTKGADVLIGGSRASS 384
S+ +V + G G GP+IH++S DK+ +++DA K ++L GG S
Sbjct: 377 SQNVVPMNTSASPISGGNLRGFM-GPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKS 435
Query: 385 LGPLFYQPTVLGNVTESMDIFYEEIFGPVA-----PLIKFKDVDEVIKRANDTDVGLAGY 439
G F PTV+ E FGP+ P +F ++ ++I N + L G
Sbjct: 436 QG-WFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIID--NTSQYALTGA 492
Query: 440 FYSQNISTIFDAAEKL--NVGMVGVN---TGEISEPAVPFGGVKNSG 481
++++ I A EKL + G +N TG + FGG + SG
Sbjct: 493 IFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW-FGGARMSG 538
>SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 548
Score = 116 bits (291), Expect = 7e-26
Identities = 98/373 (26%), Positives = 166/373 (44%), Gaps = 19/373 (5%)
Query: 131 FFKWFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIAT 190
F ++ + A +Y P R G + +TP+NF +A+ A +
Sbjct: 150 FLRFNTKYASELYASQPPENTPGVWNRMEYRPLEGFVYAITPFNF-TAIAGNLAAAPLLM 208
Query: 191 GNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFT 250
GN ++KP+ LS+ + I +AGLPAG +P + E+ + H + FT
Sbjct: 209 GNVVLMKPSDHAVLSSYIVYQIFREAGLPAGALQFIPGDAV-EVSKVCFNHPEFAGLHFT 267
Query: 251 GSTKIGQLLMGQ------SSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQ 304
GST + + L G + K + K E GG ++V A++ A+ + F
Sbjct: 268 GSTAVFRSLWGTIGENVANGKYRTYPKIVGETGGKNFHLVHSSAEIKSAVVNAVRAAFEY 327
Query: 305 SGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTH-GPLIHDKSIDKVAS 363
GQ C +R++V + ++ + + K K+ K+G D GP+IH S +K+
Sbjct: 328 QGQKCSALSRLYVSKYAWENGFRDELTKQVKSLKVGAPLTDFANFVGPVIHQASFNKLKK 387
Query: 364 LVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKD-- 421
+++ A + ++ G +A F +PTVL + DIF E+FGPV + ++D
Sbjct: 388 VLESAASDSEIEVLAGGKADDSEGFFVEPTVLLSKNPKHDIFVNELFGPVLSVYVYEDDN 447
Query: 422 VDEVIKRAN-DTDVGLAGYFYSQNISTIFDAAEKLN--VGMVGVN---TGEISEPAVPFG 475
+D V + T GL G ++Q+ + ++L G +N TG + PFG
Sbjct: 448 LDAVCDLIDTTTPYGLTGSIFAQDRVVVRKLTDRLRNAAGNFYINDKCTGAVVGEQ-PFG 506
Query: 476 GVKNSGLG-KEGS 487
G + SG K GS
Sbjct: 507 GARASGTNDKAGS 519
>7304212 [C] KOG2456 Aldehyde dehydrogenase
Length = 561
Score = 116 bits (290), Expect = 9e-26
Identities = 99/415 (23%), Positives = 186/415 (43%), Gaps = 43/415 (10%)
Query: 63 VSDFNKAIEIAHDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSL 122
+++F+ ++ A AF + + NV R + L+N+ E++ ++ L + +P ++SL
Sbjct: 1 MANFDDTLQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESL 60
Query: 123 GEIVYSAMFFK------------WFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGIL 170
+ F K W E P S V+ + P GV+ ++
Sbjct: 61 ---IVETEFMKNDIRHILFQLDEWVQSEKPP------KSFVNMMDDVQIYNDPFGVVLVI 111
Query: 171 TPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPTNH 230
WN+P ++ +A IA GN VIKP+ A + + K C +
Sbjct: 112 GAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPK--YLDNDCYPVVCGG 169
Query: 231 TSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADL 290
SE E + ++ I +TGST++G+++ ++ K + ++ELGG +P + K D+
Sbjct: 170 PSETAELL--NQRFDYIFYTGSTRVGKII--HAAANKYLTPTTLELGGKSPCYIDKSVDM 225
Query: 291 DRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHG 350
A+ I+ K GQTCI + I +++ ++F D + + + G+ Q
Sbjct: 226 RTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEWY--GENIQSSPDLS 283
Query: 351 PLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIF 410
+I+ + ++ L++ + V +GG+ +S F +PT+L +V E+ I EEIF
Sbjct: 284 RVINANNFQRLLGLMKSGR-----VAVGGNYDAS--ERFIEPTILVDVKETDPIMEEEIF 336
Query: 411 GPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTG 465
GP+ P+ + + IK N + L Y ++ AE N+ + G +G
Sbjct: 337 GPILPIFNVESAYDAIKFINARESPLVLYIFT-------PTAEVQNLFINGTQSG 384
>Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 114 bits (285), Expect = 3e-25
Identities = 118/482 (24%), Positives = 213/482 (43%), Gaps = 26/482 (5%)
Query: 37 WTETDDKFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQILDNIY 96
WT +D ++ V+ + G + + S NKAIE A A + + +RAQI
Sbjct: 74 WT-SDVQYQVSPFNHGHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAA 132
Query: 97 NLML--ENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDIIPSAVSSD 154
+++ + LAK + + + + FF++ A+ A + G P +V
Sbjct: 133 DMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQ-PISVPPS 191
Query: 155 QKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAE 214
R G + ++P+NF + AP + GN + KP+ L++ A+ I
Sbjct: 192 TNSTVYRGLEGFVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILR 250
Query: 215 KAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKN----IK 270
+AGLP + +P + G+ V E + I FTGS + L Q ++ +
Sbjct: 251 EAGLPPNIIQFVPADGPL-FGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFP 309
Query: 271 KFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLV 330
+ + E GG + V + AD++ + G + F GQ C +R++V L+ + RL+
Sbjct: 310 RLAGECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLL 369
Query: 331 DKIDKTFKLGDGFQD-GVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGPLF 389
++ + K+GD +D G +I KS ++ ++ A++ + ++ G + F
Sbjct: 370 EEHSR-IKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYF 428
Query: 390 YQPTVLGNVTESMDIFYEEIFGPVA-----PLIKFKDVDEVIKRANDTDVGLAGYFYSQN 444
+P ++ + I EEIFGPV P K+K+ +++ + T GL G +SQ+
Sbjct: 429 VEPCIVESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVD--STTSYGLTGAVFSQD 486
Query: 445 ISTIFDAAEKL-----NVGMVGVNTGEISEPAVPFGGVKNSGLG-KEGSKYGIDDYTELK 498
+ +A + L N + +TG I PFGG + SG K G + I +T +
Sbjct: 487 KDVVQEATKVLRNAAGNFYINDKSTGSIVGQQ-PFGGARASGTNDKPGGPHYILRWTSPQ 545
Query: 499 AI 500
I
Sbjct: 546 VI 547
>Hs20546780 [C] KOG2450 Aldehyde dehydrogenase
Length = 637
Score = 108 bits (271), Expect = 1e-23
Identities = 85/333 (25%), Positives = 154/333 (45%), Gaps = 16/333 (4%)
Query: 164 LGVIGILTPWNFPSAMIARKLAPVIATGNTCV--IKPAHETPLSALALGVIAEKAGLPAG 221
+GVIG++ P F + ++ P +A G T V + PA PL L +A + G G
Sbjct: 1 MGVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPL---LLAQLAGELGPFPG 57
Query: 222 VCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAP 281
+ N+L + + + + ++K+ F G+ + G+ L + S + + LG +
Sbjct: 58 ILNVL--SGPASLVPILASQPGIRKVAFCGAPEEGRAL--RRSLAGECAELGLALGTESL 113
Query: 282 YIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFKLGD 341
++ AD+D A++G++ + G + R+ + E ++DE +RL +++ + + G
Sbjct: 114 LLLTDTADVDSAVEGVVDAAWSDRGPGGL---RLLIQESVWDEAMRRLQERMGR-LRSGR 169
Query: 342 GFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTES 401
G V G + D V V++A+++GA V G S FY PT++ N+ +
Sbjct: 170 GLDGAVDMGAR-GAAACDLVQRFVREAQSQGAQVFQAGDVPSERP--FYPPTLVSNLPPA 226
Query: 402 MDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVG 461
E+ PV F+ E + AN T G + +S+ + + L VG V
Sbjct: 227 SPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQALELGYGLQVGTVW 286
Query: 462 VNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDY 494
+N + +P+VP GG K SG G G+ +Y
Sbjct: 287 INAHGLRDPSVPTGGCKESGCSWHGGPDGLYEY 319
Score = 62.8 bits (151), Expect = 1e-09
Identities = 58/211 (27%), Positives = 96/211 (45%), Gaps = 7/211 (3%)
Query: 50 STGDTIREVTNCGVSDFNKAIEIAHDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKI 109
S+G+ V G D A+E AH AF + + RA +L + + K LA
Sbjct: 385 SSGNLHGYVAEGGAKDIRGAVEAAHQAFPGWAGQSPGARAALLWALAAALERRKSTLASR 444
Query: 110 LTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGI 169
L + G K + E+ SA + + + G + A + +R+PLGV+ +
Sbjct: 445 LERQ-GAELKAAEAEVELSARRLRAWGARV-QAQGHTLQVA-GLRGPVLRLREPLGVLAV 501
Query: 170 LTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGL-PAGVCNILPT 228
+ P +P LAP +A GNT V+ P+ PL LAL V + A + PAG+ N++ T
Sbjct: 502 VCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPL--LALEVCQDMATVFPAGLANVV-T 558
Query: 229 NHTSEIGEYVCEHELVKKITFTGSTKIGQLL 259
+ + H+ V+ + + GS + Q +
Sbjct: 559 GDRDHLTRCLALHQDVQAMWYFGSAQGSQFV 589
>7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 574
Score = 104 bits (259), Expect = 4e-22
Identities = 112/451 (24%), Positives = 192/451 (41%), Gaps = 24/451 (5%)
Query: 68 KAIEIAHDAFGTFRQTNVRERAQILDNIYNLMLEN-KQDLAKILTLENGKPYK----DSL 122
KAI+ A + + + ++ +R +I + +LM +QDL L K DS
Sbjct: 113 KAIKTAVETQPKWDRVSIADRLKIWEKAADLMATTYRQDLNAATMLGQSKTAIQAEIDSA 172
Query: 123 GEIVYSAMFFKWFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIAR 182
E++ +F +E + I + + R G I ++P+NF +
Sbjct: 173 AELIDFIRMNAYFLKEVTKYQP--ISENIKVTKNSLRYRGIDGFIAAVSPFNFTAIGGNL 230
Query: 183 KLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHE 242
P + GN + KP+ LS + I +AG+P GV N +P + G+ +
Sbjct: 231 SYTPALM-GNGVLWKPSDTAMLSNWIIFKIMREAGVPDGVVNFVPADGPV-FGDTITASP 288
Query: 243 LVKKITFTGSTKIGQLLMGQSSKG----KNIKKFSMELGGNAPYIVFKDADLDRALDGII 298
+ I FTGS L Q N + + E GG + + AD++ + I
Sbjct: 289 HLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPRLTGECGGKNFHFIHASADVESVVTSTI 348
Query: 299 GCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSI 358
F GQ C +R++V E L+ + + LV + K K+GD +I DK+
Sbjct: 349 RSAFEYCGQKCSACSRMYVPESLWPQIKEGLVCEAAK-LKIGDVQDFSSFTSAVIDDKAF 407
Query: 359 DKVASLVQDAK-TKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLI 417
++ ++ AK + ++L GG+ + S G F PT++ + I EEIFGPV +
Sbjct: 408 KRITGYIEHAKKSPNLEILAGGTYSDSKG-YFVNPTIVLSKDPKDRIMTEEIFGPVLSIY 466
Query: 418 KFKDVD--EVIKRAN-DTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAV-- 472
+K+ D E +K + T L G + Q+ + A ++ + + S +V
Sbjct: 467 VYKESDLLETMKLVHTSTKFALTGAVFGQDEDFVKCALQEFKMAAGNFYINDKSTGSVVG 526
Query: 473 --PFGGVKNSGLG-KEGSKYGIDDYTELKAI 500
PFGG + SG K G + I +T ++I
Sbjct: 527 QQPFGGGRMSGTNDKAGGPHYILRWTSPQSI 557
>At4g36250 [C] KOG2456 Aldehyde dehydrogenase
Length = 433
Score = 101 bits (251), Expect = 3e-21
Identities = 100/440 (22%), Positives = 188/440 (42%), Gaps = 79/440 (17%)
Query: 75 DAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGK----PYKDSLGEIVYSAM 130
+ F + R +++ R + IY ++ +N+ + L + GK ++D LG ++ +A
Sbjct: 17 ETFASGRTRSLKWRKAQIGAIYEMVKDNEDKICNALFQDLGKHSTEAFRDELGVVLRTAT 76
Query: 131 FF-----KWFAEEAPRIYGDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLA 185
KW + ++ P+ K I +P G + +L+ WNFP ++ L
Sbjct: 77 VAINCLDKWAVPKHSKLPLLFYPA------KGKVISEPYGTVLVLSSWNFPISLSLDPLI 130
Query: 186 PVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVK 245
IA GNT ++K + +P +A A A L ++ ++ + +H+
Sbjct: 131 GAIAAGNTVLLKSSELSP-NASAFLAKTIPAYLDTKAIKVIEGG--PDVATILLQHQW-D 186
Query: 246 KITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQS 305
KI FTGS KIG+++M +++ ++ ++ELGG
Sbjct: 187 KIFFTGSPKIGRIIMAAAAQ--HLTPVTLELGG--------------------------- 217
Query: 306 GQTCICANRIFVHEDLYDEFSKRLVDKIDKTFK--LGDGFQDGVTHGPLIHDKSIDKVAS 363
++CI + + + + F+ L+D + T K G+ ++ + + + +++
Sbjct: 218 -KSCISVDYVLIEKS----FAPTLIDMLKPTIKSFFGENPKESGCLSRIANKHHVQRLSR 272
Query: 364 LVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVD 423
L+ D + PT+L + +I EEIFGP+ P+I +D+
Sbjct: 273 LLSDPR----------------------PTILLDPPLDSEIMNEEIFGPILPIITVRDIQ 310
Query: 424 EVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTGEISE--PAVPFGGVKNSG 481
E I N LA Y ++ + + + + G V N I A+PFGGV SG
Sbjct: 311 ESIGIINTKPKPLAIYAFTNDENLKTRILSETSSGSVTFNDVMIQYMCDALPFGGVGESG 370
Query: 482 LGKEGSKYGIDDYTELKAII 501
+G+ KY D ++ KAI+
Sbjct: 371 IGRYHGKYSFDCFSHEKAIM 390
>7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 560
Score = 81.3 bits (199), Expect = 3e-15
Identities = 104/443 (23%), Positives = 182/443 (40%), Gaps = 37/443 (8%)
Query: 69 AIEIAHDAFGTFRQTNVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDS------- 121
AI+ A A GT+ + +R I ++ E++ L L + K D+
Sbjct: 105 AIKSALSAQGTWSLVPIAQRLAIWRRAATIIEEDELRLRVFLMMTLSKTADDATRDIRRL 164
Query: 122 LGEIVYSAMFFKWFAEEAPRIYGD--IIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAM 179
L + +A + + +E I GD + PS F +R G + L P+ +
Sbjct: 165 LTSLRANADYLEHLSELRFEIQGDMNVFPS--------FHLRPMDGFVAALAPFESVALS 216
Query: 180 IARKLAPVIATGNTCVIKPAHET-PLSALALGVIAEKAGLPAGVCNILPTNH---TSEIG 235
+ L P + GNT + P+ E P+S L E AGLP+GV N +P N I
Sbjct: 217 SSLALCPALM-GNTVLWNPSLEVAPVSYLIFRAFQE-AGLPSGVINFVPANERLFLDTIT 274
Query: 236 EYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSMELGGNAPYIVFKDADLDRALD 295
+ V L + + + +L+ + + + E G + V A ++ +
Sbjct: 275 DAVHFAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVS 334
Query: 296 GIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHD 355
+ F +GQ +R++V ++ + LV+ ++ +GD + G ++H
Sbjct: 335 ATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQ-LTIGDPIESETDIGAMVHI 393
Query: 356 KSIDKVASLVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMD-IFYEEIFGPVA 414
++ L+Q +TK + L GGS S G F PT++ V++ +D + E GP
Sbjct: 394 NDFRRMQKLLQ--RTKNMEQLCGGSCDDSTG-RFVDPTIV-RVSDPLDPLLCEPCCGPFL 449
Query: 415 PLIKFKD--VDEVIK-RANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTGE----I 467
P+ + D E +K AN + L+G ++ I +L + + E
Sbjct: 450 PVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTGS 509
Query: 468 SEPAVPFGGVKNSGLG-KEGSKY 489
+ PFGG + SG K GS Y
Sbjct: 510 TYGLTPFGGNRLSGTNDKSGSAY 532
>7300788 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 1590
Score = 79.7 bits (195), Expect = 9e-15
Identities = 89/359 (24%), Positives = 163/359 (44%), Gaps = 36/359 (10%)
Query: 165 GVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAGLPAGVCN 224
G + ++P+NF P + GN+ + KP+ LS + +AG+P GV N
Sbjct: 235 GFVAAISPFNFTGIAANLAYTPALM-GNSVIWKPSDSAILSNYFVFKALREAGVPDGVVN 293
Query: 225 ILPTNHTSEIGEYVCEHELVKKITFTGSTKI----GQLLMGQSSKGKNIKKFSMELGGNA 280
+P T+ V +H + I FTG++ + QL+ + +N + E GG
Sbjct: 294 FVPAEETT-FASVVTQHPKLAGINFTGTSTVLKVLWQLVAQNINFYQNYPRLVGEGGGKN 352
Query: 281 PYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYD--------EFSKRLVDK 332
+ V A+ + A+ I F +GQ C + ++V E L+ E + LV +
Sbjct: 353 FHFVHSSAEPETAVACTIRAAFEYAGQKCSSCSMLYVPESLWQNHIREPLLEITASLVVR 412
Query: 333 IDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDA-KTKGADVLIGGSRASSLGPLFYQ 391
D T+ D F V I+ ++ D++ ++ ++ +L+GGS G +
Sbjct: 413 QDATY--CDSFCSAV-----INRRAYDRIYMWLRYIDQSPSCQILVGGSCDKRRG-YYVD 464
Query: 392 PTVLGNVTESMD--IFYEEIFGPVAPLIKFKD--VDEVIKRANDTDVGLAGYFYSQNIST 447
PTV+ + + +D I EE+ P+ + + D + E +++ + GL G ++Q+ +
Sbjct: 465 PTVV--LVKDLDNIICREELLAPILGVYVYPDHKLKETMEKVAQINHGLTGSVFAQDQNF 522
Query: 448 IFDA--AEKLNVGMVGVN---TGEISEPAVPFGGVKNSGLG-KEGSKYGIDDYTELKAI 500
I +A A ++NVG + VN TG + PFG +G K G+ + + +T + I
Sbjct: 523 IEEAYDAFRVNVGNLNVNDKSTG-LMVGQQPFGAGHMTGTSDKLGTPHSLLRWTSPQVI 580
>Hs20481620 [C] KOG2456 Aldehyde dehydrogenase
Length = 292
Score = 73.9 bits (180), Expect = 5e-13
Identities = 54/211 (25%), Positives = 101/211 (47%), Gaps = 14/211 (6%)
Query: 158 FTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETPLSALALGVIAEKAG 217
F ++P G++ I+ PWN+P + L +A GN V+KP+ +S ++AE
Sbjct: 62 FIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSE---ISKNVEKILAEV-- 116
Query: 218 LPAGV---CNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQSSKGKNIKKFSM 274
LP V C + E G+ + EH I FTGS ++G+++M ++ K++ ++
Sbjct: 117 LPQYVDQSCFAVVLGGPQETGQ-LLEHRF-DYIFFTGSPRVGKIVM--TAAAKHLTPVTL 172
Query: 275 ELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYDEFSKRLVDKID 334
ELGG P V + D + + ++ +GQTC+ + + ++ + L I
Sbjct: 173 ELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTIT 232
Query: 335 KTFKLGDGFQDGVTHGPLIHDKSIDKVASLV 365
+ + GD Q G +I+ K ++ +L+
Sbjct: 233 RFY--GDDPQSSPNLGRIINQKQFQRLRALL 261
>At4g34240 [C] KOG2456 Aldehyde dehydrogenase
Length = 533
Score = 64.7 bits (156), Expect = 3e-10
Identities = 44/201 (21%), Positives = 94/201 (45%), Gaps = 11/201 (5%)
Query: 305 SGQTCICANRIFVHEDLYDEFSKRLVDKIDKTFK--LGDGFQDGVTHGPLIHDKSIDKVA 362
SGQ CI + + +D F+ +L+D + + G + +++ ++
Sbjct: 295 SGQACIGVDYVITTKD----FASKLIDALKTELETFFGQNALESKDLSRIVNSFHFKRLE 350
Query: 363 SLVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDV 422
S++++ A+ ++ G R + L PT+L +V E+ + EEIFGP+ P+I + +
Sbjct: 351 SMLKENGV--ANKIVHGGRITE-DKLKISPTILLDVPEASSMMQEEIFGPLLPIITVQKI 407
Query: 423 DEVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTG--EISEPAVPFGGVKNS 480
++ + LA Y ++ N + ++ G + +N ++ +PFGGV S
Sbjct: 408 EDGFQVIRSKPKPLAAYLFTNNKELEKQFVQDVSAGGITINDTVLHVTVKDLPFGGVGES 467
Query: 481 GLGKEGSKYGIDDYTELKAII 501
G+G K+ + ++ K ++
Sbjct: 468 GIGAYHGKFSYETFSHKKGVL 488
>Hs20479244 [C] KOG2450 Aldehyde dehydrogenase
Length = 292
Score = 63.2 bits (152), Expect = 9e-10
Identities = 40/136 (29%), Positives = 63/136 (45%), Gaps = 2/136 (1%)
Query: 359 DKVASLVQDAKTKGADVLIGGSRASSLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIK 418
D V V++A+++GA V G S FY PT++ N+ + E+ PV
Sbjct: 32 DLVQRFVREAQSQGAQVFQAGDVPSERP--FYPPTLVSNLPPASPCAQVEVPWPVVVASP 89
Query: 419 FKDVDEVIKRANDTDVGLAGYFYSQNISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVK 478
F+ E + AN T G + +S+ + + L VG V +N + +P+VP GG K
Sbjct: 90 FRTAKEALLVANGTPRGGSASVWSERLGQALELGYGLQVGTVWINAHGLRDPSVPTGGCK 149
Query: 479 NSGLGKEGSKYGIDDY 494
SG G G+ +Y
Sbjct: 150 ESGCSWHGGPDGLYEY 165
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.138 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,626,976
Number of Sequences: 60738
Number of extensions: 1322782
Number of successful extensions: 3265
Number of sequences better than 1.0e-05: 75
Number of HSP's better than 0.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2879
Number of HSP's gapped (non-prelim): 79
length of query: 504
length of database: 30,389,216
effective HSP length: 111
effective length of query: 393
effective length of database: 23,647,298
effective search space: 9293388114
effective search space used: 9293388114
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)