ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3363 good C KOG2617 Energy production and conversion Citrate synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3363 1177776 1179221 482
(482 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNR001c [C] KOG2617 Citrate synthase 761 0.0
YCR005c [C] KOG2617 Citrate synthase 683 0.0
SPAC6C3.04 [C] KOG2617 Citrate synthase 555 e-158
Hs4758076 [C] KOG2617 Citrate synthase 533 e-151
7290712 [C] KOG2617 Citrate synthase 516 e-146
CE00513 [C] KOG2617 Citrate synthase 497 e-140
At2g44350 [C] KOG2617 Citrate synthase 484 e-136
At3g60100 [C] KOG2617 Citrate synthase 482 e-136
YPR001w [C] KOG2617 Citrate synthase 370 e-102
7299562 [C] KOG2617 Citrate synthase 360 3e-99
At2g42790 [C] KOG2617 Citrate synthase 90 9e-18
At3g58750 [C] KOG2617 Citrate synthase 88 3e-17
At3g58740 [C] KOG2617 Citrate synthase 65 2e-10
Hs17434182 [C] KOG2617 Citrate synthase 59 1e-08
Hs18562547 [C] KOG2617 Citrate synthase 58 3e-08
>YNR001c [C] KOG2617 Citrate synthase
Length = 479
Score = 761 bits (1965), Expect = 0.0
Identities = 386/482 (80%), Positives = 416/482 (86%), Gaps = 9/482 (1%)
Query: 1 MSTTMLSTRNALARGLLRTSGGAAGASRNNLLLSLVASRYYSNG-EKTLKQRFAEIFPEK 59
+STT +++ L+RG R A L +L+ +R+YS+ E+TLK+RFAEI P K
Sbjct: 5 LSTT---SKSFLSRGSTRQCQNMQKA-----LFALLNARHYSSASEQTLKERFAEIIPAK 56
Query: 60 AEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIRFRGRTIPDIQKE 119
AEEIK+ KKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIRFRGRTIP+IQ+E
Sbjct: 57 AEEIKKFKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIRFRGRTIPEIQRE 116
Query: 120 LPKAADGEEPLPEAIFWLLLTGEVPTETQVKALSADLASRSELPAHVESLLDNLPKDLHP 179
LPKA EPLPEA+FWLLLTGE+PT+ QVKALSADLA+RSE+P HV LLD+LPKDLHP
Sbjct: 117 LPKAEGSTEPLPEALFWLLLTGEIPTDAQVKALSADLAARSEIPEHVIQLLDSLPKDLHP 176
Query: 180 MAQFSMAVTALESESKFAKAYAQGVSKKDYWNYTFEDSLDLLGKLPVIASKIYRNVFKDG 239
MAQFS+AVTALESESKFAKAYAQGVSKK+YW+YTFEDSLDLLGKLPVIASKIYRNVFKDG
Sbjct: 177 MAQFSIAVTALESESKFAKAYAQGVSKKEYWSYTFEDSLDLLGKLPVIASKIYRNVFKDG 236
Query: 240 KITSIDQNADYGKNLAHLLGYQNKEFVDLMRLYLTIHSDHEGGNVSAHTTHLVXXXXXXX 299
KITS D NADYGKNLA LLGY+NK+F+DLMRLYLTIHSDHEGGNVSAHTTHLV
Sbjct: 237 KITSTDPNADYGKNLAQLLGYENKDFIDLMRLYLTIHSDHEGGNVSAHTTHLVGSALSSP 296
Query: 300 XXXXXXXXXXXXXXXHGRANQEVLEWLFKLREEVKGDYSPATIEKYLWDTLNSGRVVPGY 359
HGRANQEVLEWLFKLREEVKGDYS TIEKYLWDTLN+GRVVPGY
Sbjct: 297 YLSLAAGLNGLAGPLHGRANQEVLEWLFKLREEVKGDYSKETIEKYLWDTLNAGRVVPGY 356
Query: 360 GHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPKVLTKHGKTKNPWPNVDSHS 419
GHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAP VLTKHGKTKNPWPNVDSHS
Sbjct: 357 GHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPGVLTKHGKTKNPWPNVDSHS 416
Query: 420 GVLLQYYGLTEASFYTVLFGVARAFGVLPQLIIDRAVGQPIERPKSFSTEKYIELVQSIN 479
GVLLQYYGLTEASFYTVLFGVARA GVLPQLIIDRAVG PIERPKSFSTEKY ELV+ I
Sbjct: 417 GVLLQYYGLTEASFYTVLFGVARAIGVLPQLIIDRAVGAPIERPKSFSTEKYKELVKKIE 476
Query: 480 AK 481
+K
Sbjct: 477 SK 478
>YCR005c [C] KOG2617 Citrate synthase
Length = 460
Score = 683 bits (1762), Expect = 0.0
Identities = 335/448 (74%), Positives = 380/448 (84%), Gaps = 2/448 (0%)
Query: 36 VASRYYSNG--EKTLKQRFAEIFPEKAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGL 93
VAS SN EKTLK+RF+EI+P A+++++ KEHGKT I +VLLEQ YGGMRGI G
Sbjct: 12 VASYLQSNSSQEKTLKERFSEIYPIHAQDVRQFVKEHGKTKISDVLLEQVYGGMRGIPGS 71
Query: 94 VWEGSVLDPEEGIRFRGRTIPDIQKELPKAADGEEPLPEAIFWLLLTGEVPTETQVKALS 153
VWEGSVLDPE+GIRFRGRTI DIQK+LPKA +PLPEA+FWLLLTGEVPT+ QV+ LS
Sbjct: 72 VWEGSVLDPEDGIRFRGRTIADIQKDLPKAKGSSQPLPEALFWLLLTGEVPTQAQVENLS 131
Query: 154 ADLASRSELPAHVESLLDNLPKDLHPMAQFSMAVTALESESKFAKAYAQGVSKKDYWNYT 213
ADL SRSELP+HV LLDNLPKDLHPMAQFS+AVTALESESKFAKAYAQG+SK+DYW+YT
Sbjct: 132 ADLMSRSELPSHVVQLLDNLPKDLHPMAQFSIAVTALESESKFAKAYAQGISKQDYWSYT 191
Query: 214 FEDSLDLLGKLPVIASKIYRNVFKDGKITSIDQNADYGKNLAHLLGYQNKEFVDLMRLYL 273
FEDSLDLLGKLPVIA+KIYRNVFKDGK+ +D NADY KNL +L+G ++++FVDLMRLYL
Sbjct: 192 FEDSLDLLGKLPVIAAKIYRNVFKDGKMGEVDPNADYAKNLVNLIGSKDEDFVDLMRLYL 251
Query: 274 TIHSDHEGGNVSAHTTHLVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLEWLFKLREEV 333
TIHSDHEGGNVSAHT+HLV HGRANQEVLEWLF L+EEV
Sbjct: 252 TIHSDHEGGNVSAHTSHLVGSALSSPYLSLASGLNGLAGPLHGRANQEVLEWLFALKEEV 311
Query: 334 KGDYSPATIEKYLWDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVST 393
DYS TIEKYLWDTLNSGRV+PGYGHAVLRKTDPRY AQR+FA+ HFPDYELFKLVS+
Sbjct: 312 NDDYSKDTIEKYLWDTLNSGRVIPGYGHAVLRKTDPRYMAQRKFAMDHFPDYELFKLVSS 371
Query: 394 IYEVAPKVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVLPQLIID 453
IYEVAP VLT+HGKTKNPWPNVD+HSGVLLQYYGL E+SFYTVLFGV+RAFG+L QLI D
Sbjct: 372 IYEVAPGVLTEHGKTKNPWPNVDAHSGVLLQYYGLKESSFYTVLFGVSRAFGILAQLITD 431
Query: 454 RAVGQPIERPKSFSTEKYIELVQSINAK 481
RA+G IERPKS+STEKY ELV++I +K
Sbjct: 432 RAIGASIERPKSYSTEKYKELVKNIESK 459
>SPAC6C3.04 [C] KOG2617 Citrate synthase
Length = 473
Score = 555 bits (1431), Expect = e-158
Identities = 277/478 (57%), Positives = 348/478 (71%), Gaps = 7/478 (1%)
Query: 1 MSTTMLSTRNALARGLLRTSGGAAGASRNNLLLSLVASRYYSNGEKTLKQRFAEIFPEKA 60
M+ T L++ LA LL + AS + L+ + + YS +LK R AE+ PEK
Sbjct: 1 MTNTRLASTRRLASSLL------SQASLRSRQLNPLFTSSYSTRSSSLKDRLAELIPEKQ 54
Query: 61 EEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIRFRGRTIPDIQKEL 120
EIK+ + EHG+ VIGEV + Q YGG RG++ L+WEGSVLDP EGIRFRG TIP+ QK L
Sbjct: 55 AEIKKFRAEHGQDVIGEVTINQMYGGARGVRSLIWEGSVLDPNEGIRFRGYTIPECQKLL 114
Query: 121 PKAADGEEPLPEAIFWLLLTGEVPTETQVKALSADLASRSELPAHVESLLDNLPKDLHPM 180
P + +G++PLPE++FWLL+TGE+PT +QV+ALSAD A+RS+LP VE L+D P LHPM
Sbjct: 115 PSSPNGKQPLPESLFWLLVTGEIPTLSQVQALSADWAARSQLPKFVEELIDRCPPTLHPM 174
Query: 181 AQFSMAVTALESESKFAKAYAQGVSKKDYWNYTFEDSLDLLGKLPVIASKIYRNVFKDGK 240
AQFS+AVTALE +S FAKAY +G++K DYW Y +ED +DL+ K IA +IYRN+++DG
Sbjct: 175 AQFSLAVTALEHDSAFAKAYERGMNKHDYWKYEYEDCMDLIAKTVPIAGRIYRNLYRDGV 234
Query: 241 ITSIDQNADYGKNLAHLLGY-QNKEFVDLMRLYLTIHSDHEGGNVSAHTTHLVXXXXXXX 299
+ I + D+ N A++LG+ N+EFV+LMRLYLTIH+DHEGGNVSAHT HLV
Sbjct: 235 VAPIQMDKDHSYNFANVLGFANNEEFVELMRLYLTIHADHEGGNVSAHTGHLVGSALSSP 294
Query: 300 XXXXXXXXXXXXXXXHGRANQEVLEWLFKLREEVKGDYSPATIEKYLWDTLNSGRVVPGY 359
HG ANQEVL +L +++E+ D S TI+ YLW LNSGRVVPGY
Sbjct: 295 FLSMAASLNGLAGPLHGLANQEVLNFLITMKKEIGDDLSEETIKSYLWKLLNSGRVVPGY 354
Query: 360 GHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPKVLTKHGKTKNPWPNVDSHS 419
GHAVLRKTDPRYTAQREFAL+H P +F+LVS +YE+ P VLT+HGKTKNP+PNVDSHS
Sbjct: 355 GHAVLRKTDPRYTAQREFALEHLPKDPMFQLVSRLYEIVPGVLTEHGKTKNPYPNVDSHS 414
Query: 420 GVLLQYYGLTEASFYTVLFGVARAFGVLPQLIIDRAVGQPIERPKSFSTEKYIELVQS 477
GVLLQYYGL E SFYTVLFGV+R GV QLI DRA+G PIERPKSFSTE ++V++
Sbjct: 415 GVLLQYYGLKEQSFYTVLFGVSRTLGVASQLIWDRALGLPIERPKSFSTEALKKMVET 472
>Hs4758076 [C] KOG2617 Citrate synthase
Length = 466
Score = 533 bits (1373), Expect = e-151
Identities = 257/444 (57%), Positives = 330/444 (73%), Gaps = 1/444 (0%)
Query: 35 LVASRYYSNGEKTLKQRFAEIFPEKAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLV 94
++A+R+ S LK A++ P++ IK +++HGKTV+G++ ++ YGGMRG+KGLV
Sbjct: 20 VLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLV 79
Query: 95 WEGSVLDPEEGIRFRGRTIPDIQKELPKAADGEEPLPEAIFWLLLTGEVPTETQVKALSA 154
+E SVLDP+EGIRFRG +IP+ QK LPKA GEEPLPE +FWLL+TG +PTE QV LS
Sbjct: 80 YETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLFWLLVTGCIPTEEQVSWLSK 139
Query: 155 DLASRSELPAHVESLLDNLPKDLHPMAQFSMAVTALESESKFAKAYAQGVSKKDYWNYTF 214
+ A R+ LP+HV ++LDN P +LHPM+Q S AVTAL SES FA+AYA+G+S+ YW +
Sbjct: 140 EWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESNFAQAYARGISRTKYWELIY 199
Query: 215 EDSLDLLGKLPVIASKIYRNVFKDGK-ITSIDQNADYGKNLAHLLGYQNKEFVDLMRLYL 273
EDS+DL+ KLP +A+KIYRN++ +G I +ID N D+ N ++LGY + +F +LMRLYL
Sbjct: 200 EDSVDLIAKLPCVAAKIYRNLYWEGSGIGAIDSNLDWSHNFTNMLGYTDHQFTELMRLYL 259
Query: 274 TIHSDHEGGNVSAHTTHLVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLEWLFKLREEV 333
TIHSDHEGGNVSAHT+HLV HG ANQEVL WL +L++EV
Sbjct: 260 TIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEV 319
Query: 334 KGDYSPATIEKYLWDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVST 393
D S + Y+W+TLNSGRVVPGYGHAVLRKTDPRYT QREFALKH P+ +FKLV+
Sbjct: 320 GKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPNDPMFKLVAQ 379
Query: 394 IYEVAPKVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVLPQLIID 453
+Y++ P VL + GK KNPWPNVD+HSGVLLQYYG+TE ++YTVLFGV+RA GVL QLI
Sbjct: 380 LYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWS 439
Query: 454 RAVGQPIERPKSFSTEKYIELVQS 477
RA+G P+ERPKS STE ++ V S
Sbjct: 440 RALGFPLERPKSMSTEGLMKFVDS 463
>7290712 [C] KOG2617 Citrate synthase
Length = 464
Score = 516 bits (1330), Expect = e-146
Identities = 252/432 (58%), Positives = 314/432 (72%), Gaps = 1/432 (0%)
Query: 46 KTLKQRFAEIFPEKAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEG 105
K+L+ A P++ E +K +K+HG T +GE ++ YGGMRGIK LV E SVLD +EG
Sbjct: 32 KSLRDVLAAKVPQEQERVKNFRKQHGATKMGETTIDMMYGGMRGIKALVTETSVLDADEG 91
Query: 106 IRFRGRTIPDIQKELPKAADGEEPLPEAIFWLLLTGEVPTETQVKALSADLASRSELPAH 165
IRFRG +IP+ QK LP A G EPLPE +FWLLLTGEVPT++QV+ LS + A R+ LP H
Sbjct: 92 IRFRGLSIPECQKVLPAADGGTEPLPEGLFWLLLTGEVPTKSQVQQLSREWAERAALPQH 151
Query: 166 VESLLDNLPKDLHPMAQFSMAVTALESESKFAKAYAQGVSKKDYWNYTFEDSLDLLGKLP 225
V ++L+N+P LHPM+QF+ AVTAL +SKFAKAY+ GV K YW Y +EDS+DL+ KLP
Sbjct: 152 VVTMLNNMPTTLHPMSQFAAAVTALNHDSKFAKAYSDGVHKSKYWEYVYEDSMDLIAKLP 211
Query: 226 VIASKIYRNVFKDGK-ITSIDQNADYGKNLAHLLGYQNKEFVDLMRLYLTIHSDHEGGNV 284
V+A+ IY N ++ GK SID + D+ N +LGY N F +LMRLYLTIHSDHEGGNV
Sbjct: 212 VVAATIYCNTYRGGKGSRSIDSSLDWSANFVKMLGYDNAPFTELMRLYLTIHSDHEGGNV 271
Query: 285 SAHTTHLVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLEWLFKLREEVKGDYSPATIEK 344
SAHT HLV HG ANQEVL WL KL++E + S +++
Sbjct: 272 SAHTVHLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLVWLRKLQKEAGNNPSEEQLKE 331
Query: 345 YLWDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPKVLTK 404
Y+W TL SG+VVPGYGHAVLRKTDPRYT QREFALKH P+ E F+LVS IY+V P +LT+
Sbjct: 332 YIWKTLKSGQVVPGYGHAVLRKTDPRYTCQREFALKHLPEDETFQLVSKIYKVVPPILTE 391
Query: 405 HGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVLPQLIIDRAVGQPIERPK 464
GK KNPWPNVD+HSGVLLQYYG+ E ++YTVLFGV+RA GVL L+ DRA+G PIERPK
Sbjct: 392 TGKVKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLASLVWDRALGLPIERPK 451
Query: 465 SFSTEKYIELVQ 476
SFST+ +++VQ
Sbjct: 452 SFSTDLLVKMVQ 463
>CE00513 [C] KOG2617 Citrate synthase
Length = 468
Score = 497 bits (1280), Expect = e-140
Identities = 246/442 (55%), Positives = 315/442 (70%), Gaps = 3/442 (0%)
Query: 42 SNGEKTLKQRFAEIFPEKAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLD 101
+ G LK+ ++ P ++K + EHG TV+ V ++ YGGMR +KG+V E SVLD
Sbjct: 29 AEGSTNLKEVLSKKIPAHNAKVKSFRTEHGSTVVQNVNIDMIYGGMRSMKGMVTETSVLD 88
Query: 102 PEEGIRFRGRTIPDIQKELPKAADGEEPLPEAIFWLLLTGEVPTETQVKALSADLASRSE 161
PEEGIRFRG +IP+ QK LPKA GEEPLPEAI+WLL TG+VP+E Q A++ + +R++
Sbjct: 89 PEEGIRFRGYSIPECQKLLPKAKGGEEPLPEAIWWLLCTGDVPSEAQTAAITKEWNARAD 148
Query: 162 LPAHVESLLDNLPKDLHPMAQFSMAVTALESESKFAKAYAQGVSKKDYWNYTFEDSLDLL 221
LP HV +LDN P +LHPMAQF A+ AL +ESKFA AYA+GV+K YW Y +EDS+DLL
Sbjct: 149 LPTHVVRMLDNFPDNLHPMAQFIAAIAALNNESKFAGAYARGVAKASYWEYAYEDSMDLL 208
Query: 222 GKLPVIASKIYRNVFKDGKITS-IDQNADYGKNLAHLLGYQNKEFVDLMRLYLTIHSDHE 280
KLP +A+ IYRN+++DG S ID D+ N + +LGY + F +LMRLYL IHSDHE
Sbjct: 209 AKLPTVAAIIYRNLYRDGSAVSVIDPKKDWSANFSSMLGYDDPLFAELMRLYLVIHSDHE 268
Query: 281 GGNVSAHTTHLVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLEWLFKLREEVKGDYSPA 340
GGNVSAHT+HLV HG ANQEVL +L K+ E+ +Y+
Sbjct: 269 GGNVSAHTSHLVGSALSDPYLSFSAAMAGLAGPLHGLANQEVLVFLNKIVGEIGFNYTEE 328
Query: 341 TIEKYLWDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPK 400
+++++W L SG+VVPGYGHAVLRKTDPRY QREFALKH P+ +LFKLVST+Y++ P
Sbjct: 329 QLKEWVWKHLKSGQVVPGYGHAVLRKTDPRYECQREFALKHLPNDDLFKLVSTLYKITPG 388
Query: 401 VLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVLPQLIIDRAVGQPI 460
+L + GK KNPWPNVDSHSGVLLQY+G+TE SFYTVLFGV+RA G L QLI R +G P+
Sbjct: 389 ILLEQGKAKNPWPNVDSHSGVLLQYFGMTEMSFYTVLFGVSRALGCLSQLIWARGMGLPL 448
Query: 461 ERPKSFSTEKYIELVQSINAKK 482
ERPKS ST+ I+L ++ AKK
Sbjct: 449 ERPKSHSTDGLIKL--ALAAKK 468
>At2g44350 [C] KOG2617 Citrate synthase
Length = 474
Score = 484 bits (1245), Expect = e-136
Identities = 228/428 (53%), Positives = 304/428 (70%)
Query: 42 SNGEKTLKQRFAEIFPEKAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLD 101
S+ + LK + E+ PE+ + +K+LK EHGK +G + ++ GGMRG+ GL+WE S+LD
Sbjct: 35 SSTDLDLKSQLQELIPEQQDRLKKLKSEHGKVQLGNITVDMVIGGMRGMTGLLWETSLLD 94
Query: 102 PEEGIRFRGRTIPDIQKELPKAADGEEPLPEAIFWLLLTGEVPTETQVKALSADLASRSE 161
PEEGIRFRG +IP+ QK LP A G EPLPE + WLLLTG+VP++ QV+ALS DLA+R+
Sbjct: 95 PEEGIRFRGLSIPECQKVLPTAQSGAEPLPEGLLWLLLTGKVPSKEQVEALSKDLANRAA 154
Query: 162 LPAHVESLLDNLPKDLHPMAQFSMAVTALESESKFAKAYAQGVSKKDYWNYTFEDSLDLL 221
+P +V + +D LP HPM QF+ V AL+ +S+F KAY G+ K +W T+ED L+L+
Sbjct: 155 VPDYVYNAIDALPSTAHPMTQFASGVMALQVQSEFQKAYENGIHKSKFWEPTYEDCLNLI 214
Query: 222 GKLPVIASKIYRNVFKDGKITSIDQNADYGKNLAHLLGYQNKEFVDLMRLYLTIHSDHEG 281
++PV+A+ +YR ++K+G D++ DYG N +H+LG+ +++ +LMRLY+TIHSDHEG
Sbjct: 215 ARVPVVAAYVYRRMYKNGDSIPSDKSLDYGANFSHMLGFDDEKVKELMRLYITIHSDHEG 274
Query: 282 GNVSAHTTHLVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLEWLFKLREEVKGDYSPAT 341
GNVSAHT HLV HG ANQEVL W+ + EE D S
Sbjct: 275 GNVSAHTGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKSVVEECGEDISKEQ 334
Query: 342 IEKYLWDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPKV 401
+++Y+W TLNSG+V+PGYGH VLR TDPRY QREFALKH PD LF+LVS +YEV P V
Sbjct: 335 LKEYVWKTLNSGKVIPGYGHGVLRNTDPRYVCQREFALKHLPDDPLFQLVSKLYEVVPPV 394
Query: 402 LTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVLPQLIIDRAVGQPIE 461
LT+ GK KNPWPNVD+HSGVLL +YGLTEA +YTVLFGV+R+ G+ QLI DRA+G +E
Sbjct: 395 LTELGKVKNPWPNVDAHSGVLLNHYGLTEARYYTVLFGVSRSLGICSQLIWDRALGLALE 454
Query: 462 RPKSFSTE 469
RPKS + +
Sbjct: 455 RPKSVTMD 462
>At3g60100 [C] KOG2617 Citrate synthase
Length = 433
Score = 482 bits (1241), Expect = e-136
Identities = 233/423 (55%), Positives = 298/423 (70%), Gaps = 6/423 (1%)
Query: 48 LKQRFAEIFPEKAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGIR 107
LK + EI PE+ + +K+LK E GK +G + ++ GGMRG+ GL+WE S+LD +EGIR
Sbjct: 6 LKSQMQEIIPEQQDRLKKLKSEQGKVPVGNITVDMVLGGMRGMTGLLWETSLLDADEGIR 65
Query: 108 FRGRTIPDIQKELPKAADGEEPLPEAIFWLLLTGEVPTETQVKALSADLASRSELPAHVE 167
FRG +IP+ QK LP A GEEPLPE++ WLLLTG+VPT+ Q ALS +LA R+ +PA
Sbjct: 66 FRGMSIPECQKILPSAESGEEPLPESLLWLLLTGKVPTKEQANALSTELAHRAAVPA--- 122
Query: 168 SLLDNLPKDLHPMAQFSMAVTALESESKFAKAYAQG-VSKKDYWNYTFEDSLDLLGKLPV 226
+D LP HPM QF+ V AL+ +S+F KAY QG +SK YW TFED+L+L+ ++PV
Sbjct: 123 --IDALPSTAHPMTQFASGVMALQVQSEFQKAYEQGDISKSKYWEPTFEDALNLIARVPV 180
Query: 227 IASKIYRNVFKDGKITSIDQNADYGKNLAHLLGYQNKEFVDLMRLYLTIHSDHEGGNVSA 286
+AS +YR ++KDG I +D + DYG N +H+LG+ + + +LMRLY+TIHSDHEGGNVSA
Sbjct: 181 VASYVYRRMYKDGSIIPLDDSLDYGANFSHMLGFDSPQMKELMRLYVTIHSDHEGGNVSA 240
Query: 287 HTTHLVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLEWLFKLREEVKGDYSPATIEKYL 346
H HLV HG ANQEVL W+ + EE S ++ Y+
Sbjct: 241 HAGHLVGSALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKLVVEECGESISKEQLKDYV 300
Query: 347 WDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPKVLTKHG 406
W TLNSG+VVPGYGH VLRKTDPRY QREFALKH PD LF+LVS +YEV P +LT+ G
Sbjct: 301 WKTLNSGKVVPGYGHGVLRKTDPRYICQREFALKHLPDDPLFQLVSKLYEVVPPILTELG 360
Query: 407 KTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVLPQLIIDRAVGQPIERPKSF 466
K KNPWPNVD+HSGVLL YYGLTEA +YTVLFGV+R+ G+ QLI DRA+G P+ERPKS
Sbjct: 361 KVKNPWPNVDAHSGVLLNYYGLTEARYYTVLFGVSRSLGICSQLIWDRALGLPLERPKSV 420
Query: 467 STE 469
+ +
Sbjct: 421 NMD 423
>YPR001w [C] KOG2617 Citrate synthase
Length = 486
Score = 370 bits (949), Expect = e-102
Identities = 196/471 (41%), Positives = 277/471 (58%), Gaps = 22/471 (4%)
Query: 34 SLVASRYYSNGEKTLKQRFAEIFPEKAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGL 93
S +S + TLK+ + P+K + +K+LK +G T +G + + GGMRG + +
Sbjct: 15 SFNSSAIIKSSALTLKEALENVIPKKRDAVKKLKACYGSTFVGPITISSVLGGMRGNQSM 74
Query: 94 VWEGSVLDPEEGIRFRGRTIPDIQKELPKAA-DGEEPLPEAIFWLLLTGEVPTETQVKAL 152
W+G+ LDPE GI+F+G TI + Q LP DG+ LPE++ WLL+TG VPT Q +
Sbjct: 75 FWQGTSLDPEHGIKFQGLTIEECQNRLPNTGIDGDNFLPESMLWLLMTGGVPTFQQAASF 134
Query: 153 SADLASRS-ELPAHVESLLDNLPKDLHPMAQFSMAVTALESESKFAKAYAQG-VSKKDYW 210
+LA R +LP + E +L +LPKD+HPM Q ++ + ++ S FA Y +G + K ++W
Sbjct: 135 RKELAIRGRKLPHYTEKVLSSLPKDMHPMTQLAIGLASMNKGSLFATNYQKGLIGKMEFW 194
Query: 211 NYTFEDSLDLLGKLPVIASKIYRNVFKDGK-ITSIDQNADYGKNLAHLLGY--------- 260
T EDSL+L+ LP++ +IY N+ +G + + D+ N+ LLG
Sbjct: 195 KDTLEDSLNLIASLPLLTGRIYSNITNEGHPLGQYSEEVDWCTNICSLLGMTNGTNSSNT 254
Query: 261 ------QNKEFVDLMRLYLTIHSDHEGGNVSAHTTHLVXXXXXXXXXXXXXXXXXXXXXX 314
Q+ +F++LMRLY IH DHEGGNVSAHTTHLV
Sbjct: 255 CNLTSQQSLDFINLMRLYTGIHVDHEGGNVSAHTTHLVGSALSDPYLSYSSGIMGLAGPL 314
Query: 315 HGRANQEVLEWLFKLREEVKGDYSPATIEKYLWDTLNSGRVVPGYGHAVLRKTDPRYTAQ 374
HG A QEV+ +L ++ + I+ YLW LNS RV+PGYGHAVLRK DPR+TA
Sbjct: 315 HGLAAQEVVRFLIEMNSNISSIAREQEIKDYLWKILNSNRVIPGYGHAVLRKPDPRFTAM 374
Query: 375 REFALKHFPDYELFK---LVSTIYEVAPKVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEA 431
EFA K ++E K L+ + E+APKVL +HGK+KNP+PNVDS SG+L +YG+ E
Sbjct: 375 LEFAQKRPIEFENDKNVLLMQKLAEIAPKVLLEHGKSKNPFPNVDSASGILFYHYGIREL 434
Query: 432 SFYTVLFGVARAFGVLPQLIIDRAVGQPIERPKSFSTEKYIELVQSINAKK 482
F+TV+FG +RA G L QL+ DR +G PIERPKS + E L ++ N K
Sbjct: 435 LFFTVIFGCSRAMGPLTQLVWDRILGLPIERPKSLNLEGLEALTKASNVNK 485
>7299562 [C] KOG2617 Citrate synthase
Length = 407
Score = 360 bits (923), Expect = 3e-99
Identities = 182/395 (46%), Positives = 255/395 (64%), Gaps = 5/395 (1%)
Query: 87 MRGIKGLVWEGSVLDPEEGIRFRGRTIPDIQKELPKAADG-EEPLPEAIFWLLLTGEVPT 145
MRG+ L E S LD +GI +RG+ + D+ +LP+ +G +E PE F+LL +G +PT
Sbjct: 1 MRGLPLLFCETSSLDKNKGIYYRGKLLKDVCAKLPRVQEGTQEGTPEGCFFLLTSGSMPT 60
Query: 146 ETQVKALSADLASRSELPAHVESLLDNLPKDLHPMAQFSMAVTALESESKFAKAYAQGVS 205
+ + + ++ + R +P + ++D++ K +HPMAQ A L +S+F +AY +G
Sbjct: 61 KKEAQEVTNEWLKRGSVPRYCLRMIDSMDKRVHPMAQLCAASACLNPQSQFVEAYTKGAR 120
Query: 206 KKDYWNYTFEDSLDLLGKLPVIASKIYRNVFKDGKIT-SIDQNADYGKNLAHLLGYQNKE 264
+ DYW Y++EDS++L+ LP +A+ IY NVF+DG+ + ++ D+ N +LG K+
Sbjct: 121 RADYWKYSYEDSMNLIAMLPTVAAAIYSNVFRDGEGSREVNYEEDWSGNFCRMLGLPEKD 180
Query: 265 FVDLMRLYLTIHSDHEGGNVSAHTTHLVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLE 324
FVDLMRLY+ +H+DHE GNVSAH HLV HG ANQEVL
Sbjct: 181 FVDLMRLYMILHADHESGNVSAHACHLVGTALSDPFLSFSASMCGLAGPLHGLANQEVLV 240
Query: 325 WLFKLREEVKGDYSPATIEKYLWDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPD 384
WL KLR+ + D S ++K++ DTL G+V+PGYGHAVLR TDPR+ Q EFA+KH D
Sbjct: 241 WLTKLRKAIGDDPSDEELKKFIDDTLKGGQVIPGYGHAVLRDTDPRFVLQNEFAMKHCKD 300
Query: 385 YELFKLVSTIYEVAPKVLTKHGKTKNPWPNVDSHSGVLLQYYGLTEASFYTVLFGVARAF 444
KLV+ ++++ P+VL K K NP+PNVD+HSGVLLQ+Y L E FYTVLFGV+RA
Sbjct: 301 DPGVKLVTRLWKIIPEVLKKLNKVANPYPNVDAHSGVLLQHYCLKELKFYTVLFGVSRAL 360
Query: 445 GVLPQLIIDRAVGQPIERPKSFSTEKYIELVQSIN 479
GVL QLI RA+G PIERPKSFS+ IE+ + IN
Sbjct: 361 GVLSQLIWSRALGAPIERPKSFSS---IEICKFIN 392
>At2g42790 [C] KOG2617 Citrate synthase
Length = 509
Score = 89.7 bits (221), Expect = 9e-18
Identities = 93/398 (23%), Positives = 162/398 (40%), Gaps = 33/398 (8%)
Query: 59 KAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGI-RFRGRTIPDIQ 117
KA + K++ GK G L + Y ++ + S +D +EGI R+RG I ++
Sbjct: 71 KAVDFKKIVT--GKEDKGLKLYDPGYLNTAPVRSSI---SYIDGDEGILRYRGYPIEEM- 124
Query: 118 KELPKAADGEEPLPEAIFWLLLTGEVPTETQVKALSADLASRSELPAHVESLLDNLPKDL 177
E + +LL+ G +P+E+Q+ ++ S +P V ++ ++P D
Sbjct: 125 --------AENSTFLEVAYLLMYGNLPSESQLSDWEFAVSQHSAVPQGVLDIIQSMPHDA 176
Query: 178 HPMAQFSMAVTALESESKFAKAYAQGVSKKDYWNYTFEDSLDLLGKLPVIASKIYRNVFK 237
HPM A++AL A +G D + + ++GK P IA+ Y +
Sbjct: 177 HPMGVLVSAMSALSIFHPDANPALRGQDIYDSKQVRDKQIIRIIGKAPTIAAAAYLRMAG 236
Query: 238 DGKITSIDQNADYGKNLAHLL------GYQ-NKEFVDLMRLYLTIHSDHEGGNVSAHTTH 290
+ N Y N ++L Y+ N ++ + +H++HE +A H
Sbjct: 237 RPPVLP-SGNLPYADNFLYMLDSLGNRSYKPNPRLARVLDILFILHAEHEMNCSTAAARH 295
Query: 291 LVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLEWLFKLREEVKGDYSPATIEKYLWDTL 350
L HG AN+ VL+ L ++ + I +++
Sbjct: 296 L-ASSGVDVYTAVAGAVGALYGPLHGGANEAVLKMLSEIG-------TVENIPEFIEGVK 347
Query: 351 NSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPKVLTKHGKTKN 410
N R + G+GH V + DPR + A + F L+ + L+ K
Sbjct: 348 NRKRKMSGFGHRVYKNYDPRAKVIKNLADEVFSIVGKDPLIEVAVALEKAALSDDYFVKR 407
Query: 411 P-WPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVL 447
+PNVD +SG++ + G F+TVLF + R G L
Sbjct: 408 KLYPNVDFYSGLIYRAMGF-PPEFFTVLFAIPRMAGYL 444
>At3g58750 [C] KOG2617 Citrate synthase
Length = 514
Score = 87.8 bits (216), Expect = 3e-17
Identities = 95/399 (23%), Positives = 165/399 (40%), Gaps = 35/399 (8%)
Query: 59 KAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLVWEGSVLDPEEGI-RFRGRTIPDIQ 117
KA ++K++ GK G L + Y ++ + +D +EGI R+RG I
Sbjct: 76 KAVDLKKITT--GKDDKGLKLYDPGYLNTAPVRSSI---CYIDGDEGILRYRGYPI---- 126
Query: 118 KELPKAADGEEPLPEAIFWLLLTGEVPTETQVKALSADLASRSELPAHVESLLDNLPKDL 177
+EL +++ E + +LL+ G +P+++Q+ ++ S +P V ++ ++P D
Sbjct: 127 EELAESSTFIE-----VAYLLMYGNLPSQSQLADWEFTVSQHSAVPQGVLDIIQSMPHDA 181
Query: 178 HPMAQFSMAVTALESESKFAKAYAQGVSKKDYWNYTFEDSLDLLGKLPVIASKIY-RNVF 236
HPM A++AL A G + + +LGK P IA+ Y R
Sbjct: 182 HPMGVLVSAMSALSIFHPDANPALSGQDIYKSKQVRDKQIVRILGKAPTIAAAAYLRTAG 241
Query: 237 KDGKITSIDQNADYGKNLAHLLGYQ-------NKEFVDLMRLYLTIHSDHEGGNVSAHTT 289
+ + S N Y +N ++L N ++ + +H++HE +A
Sbjct: 242 RPPVLPS--ANLSYSENFLYMLDSMGNRSYKPNPRLARVLDILFILHAEHEMNCSTAAAR 299
Query: 290 HLVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLEWLFKLREEVKGDYSPATIEKYLWDT 349
HL HG AN+ VL+ L ++ + I ++
Sbjct: 300 HL-ASSGVDVYTACAGAVGALYGPLHGGANEAVLKMLAEIG-------TAENIPDFIEGV 351
Query: 350 LNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFKLVSTIYEVAPKVLTKHGKTK 409
N R + G+GH V + DPR ++ A + F L+ + L+ K
Sbjct: 352 KNRKRKMSGFGHRVYKNYDPRAKVIKKLADEVFSIVGRDPLIEVAVALEKAALSDEYFVK 411
Query: 410 NP-WPNVDSHSGVLLQYYGLTEASFYTVLFGVARAFGVL 447
+PNVD +SG++ + G F+TVLF V R G L
Sbjct: 412 RKLYPNVDFYSGLIYRAMGF-PPEFFTVLFAVPRMAGYL 449
>At3g58740 [C] KOG2617 Citrate synthase
Length = 480
Score = 65.1 bits (157), Expect = 2e-10
Identities = 68/340 (20%), Positives = 136/340 (40%), Gaps = 27/340 (7%)
Query: 98 SVLDPEEGI-RFRGRTIPDIQKELPKAADGEEPLPEAIFWLLLTGEVPTETQVKALSADL 156
S +D +EGI R+RG + ++ E+ + +LL+ G +P++ Q+ +
Sbjct: 107 SYIDGDEGILRYRGYPVEEL---------AEKSTYTEVTYLLIYGNLPSQRQLADWEFAI 157
Query: 157 ASRSELPAHVESLLDNLPKDLHPMAQFSMAVTALESESKFAKAYAQGVSKKDYWNYTFED 216
+ S +P V ++ ++P D+HP+ A++AL A G+ +
Sbjct: 158 SQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQ 217
Query: 217 SLDLLGKLPVIASKIYRNVFKDGKITSIDQNADYGKNLAHLL------GYQ-NKEFVDLM 269
+ +LG+ P IA+ Y + + N Y +N +++ Y+ N ++
Sbjct: 218 IVRVLGQAPTIAAAAYLRKAGKPPVQPL-SNLSYSENFLYMVESMGDRSYKPNPRLARVL 276
Query: 270 RLYLTIHSDHEGGNVSAHTTHLVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLEWLFKL 329
+ + ++HE +A HL HG A + + L ++
Sbjct: 277 DILFILQAEHEMNCSTAAARHL-SSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEI 335
Query: 330 REEVKGDYSPATIEKYLWDTLNSGRVVPGYGHAVLRKTDPRYTAQREFALKHFPDYELFK 389
+ I +++ N R + G+GH + + DPR ++ A + F
Sbjct: 336 G-------TVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDP 388
Query: 390 LVSTIYEVAPKVLTKHGKTKNP-WPNVDSHSGVLLQYYGL 428
LV + L+ K +PNVD +SG++ + G+
Sbjct: 389 LVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGI 428
>Hs17434182 [C] KOG2617 Citrate synthase
Length = 264
Score = 59.3 bits (142), Expect = 1e-08
Identities = 32/85 (37%), Positives = 40/85 (46%)
Query: 273 LTIHSDHEGGNVSAHTTHLVXXXXXXXXXXXXXXXXXXXXXXHGRANQEVLEWLFKLREE 332
LTIHSDHE N+SAH HL HG ANQEVL WL +L++E
Sbjct: 174 LTIHSDHEHSNISAHARHLAGSTLSDPSLPFAAAMNGLAVPLHGLANQEVLVWLTQLQKE 233
Query: 333 VKGDYSPATIEKYLWDTLNSGRVVP 357
V D S ++ Y + R+ P
Sbjct: 234 VGKDVSDEKLQDYTELEMGCSRLWP 258
>Hs18562547 [C] KOG2617 Citrate synthase
Length = 93
Score = 58.2 bits (139), Expect = 3e-08
Identities = 29/74 (39%), Positives = 46/74 (61%)
Query: 35 LVASRYYSNGEKTLKQRFAEIFPEKAEEIKRLKKEHGKTVIGEVLLEQAYGGMRGIKGLV 94
++A+ + S + L+ A + P++ IK +++ GK V+G+ + YGG+RG KGLV
Sbjct: 20 VLAAWHASTSSRNLEDISAYLIPKEQARIKISRQQCGKRVVGQNTVGMMYGGLRGKKGLV 79
Query: 95 WEGSVLDPEEGIRF 108
+E SVLDP E I F
Sbjct: 80 YETSVLDPNESIHF 93
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.135 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,306,023
Number of Sequences: 60738
Number of extensions: 1153307
Number of successful extensions: 3085
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 3043
Number of HSP's gapped (non-prelim): 15
length of query: 482
length of database: 30,389,216
effective HSP length: 110
effective length of query: 372
effective length of database: 23,708,036
effective search space: 8819389392
effective search space used: 8819389392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)