ORF      STATUS       Function Best COG  Functional category                                          Pathways and functional systems
r_klactVI3421   suspect: LH   L     KOG2538  Replication, recombination and repair                          Origin recognition complex, subunit 3

BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactVI3421 1199593 1197692 -634 
         (634 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YLL004w [L] KOG2538 Origin recognition complex subunit 3              470   e-132

>YLL004w [L] KOG2538 Origin recognition complex subunit 3
          Length = 616

 Score =  470 bits (1209), Expect = e-132
 Identities = 246/640 (38%), Positives = 390/640 (60%), Gaps = 39/640 (6%)

Query: 1   MELAAFAESQKQSFVFTPKFNRDSIDSYDNGSSPVPFVKLFDGLESDESVLSRWALYNKL 60
           M ++ FA++Q+  +   P     S+   +     +PFVKL  G ES+ +V  RW LY++L
Sbjct: 10  MNVSEFADAQRSHYTVYP-----SLPQSNKNDKHIPFVKLLSGKESEVNVEKRWELYHQL 64

Query: 61  HADFHTSVDTILDSIDREVVTNISNTIQSLISNPASEITRNDFKTLILLGSDAETKLEIP 120
           H+ FH  VD I+D+I+ ++   IS+ + S  +       R  F T+ LLGSD+ TK+E+ 
Sbjct: 65  HSHFHDQVDHIIDNIEADLKAEISDLLYSETTQK-----RRCFNTIFLLGSDSTTKIELK 119

Query: 121 ADTEDCYNVLVDIEPKDAPNVRLLLKRVIFKMLESMELKLQ-----SDPNSATEEFDEEV 175
            D    YNVL+++ PK++PNVR++L+R ++K+  + + +        D N    +F E+ 
Sbjct: 120 -DESSRYNVLIELTPKESPNVRMMLRRSMYKLYSAADAEEHPTIKYEDINDEDGDFTEQ- 177

Query: 176 MKSLRLYDMIVFQLFQPTYXXXXXXXXXXXETETFYMNVLQEFIDLMKATLKIKGIQVCF 235
             +   YD+ + + F+  +           + ++   N L  FI L+K+  K   +++  
Sbjct: 178 -NNDVSYDLSLVENFKRLFGKDLAMVFNFKDVDSINFNTLDNFIILLKSAFKYDHVKISL 236

Query: 236 VLNLTTNVEKFENNLDQSIIRALSYDLKTIDLSSTKGYKYSNLIFQSFLDCVDRKLNLSP 295
           + N+ TN+   E NL QS IR L  +   +D+SS KG+KY N IFQSFLD VD KLNLS 
Sbjct: 237 IFNINTNLSNIEKNLRQSTIRLLKRNYHKLDVSSNKGFKYGNQIFQSFLDTVDGKLNLSD 296

Query: 296 KFVKFVLEKMDXXXXXXXXXXXKILDYSLMSYFFNNPYSIFIDVANINFLDEKYLDRLTK 355
           +FV+F+L KM            K+LDYSLMSYFF N +S+FID  N++FL++ YL  L++
Sbjct: 297 RFVEFILSKMANNTNHNLQLLTKMLDYSLMSYFFQNAFSVFIDPVNVDFLNDDYLKILSR 356

Query: 356 CQTFLNFVETMVNSRAPREEIVSLLNNENDTLEQFFVDFLVAENPINDKLHQIVNILENK 415
           C TF+ FVE ++   AP +EI+SLL N+N  LE+FFV+FLV ENPIN     +   LE +
Sbjct: 357 CPTFMFFVEGLIKQHAPADEILSLLTNKNRGLEEFFVEFLVRENPINGHAKFVARFLEEE 416

Query: 416 LNIYDYNLIDLYYHMLNNRLVDYLSKWEACDKFRQEFDFENVQIVFQELFTLDNNNGLLS 475
           LNI ++NLI+LY+++L  +L  YL +W AC +++    FE +  +FQELFTLDN +GLL+
Sbjct: 417 LNITNFNLIELYHNLLIGKLDSYLDRWSACKEYKDRLHFEPIDTIFQELFTLDNRSGLLT 476

Query: 476 QGLFPFFRTNLEDNLLNSERILPRSKVIQRMANNDDEIRELDRKLNELIDPIICQVFTLY 535
           Q +FP +++N+EDNLL+ E++LP        + + +    L   L++++ P++ Q+F LY
Sbjct: 477 QSIFPSYKSNIEDNLLSWEQVLP--------SLDKENYDTLSGDLDKIMAPVLGQLFKLY 528

Query: 536 REARSFINVYDFFVAFKESLPKSEIYDLLKSVLAGDEVKTSVKDKSR-KIMEKLDQDEFM 594
           REA   IN+YDF++AF+E+LPK EI + ++            KD S  K++E  +  +  
Sbjct: 529 REANMTINIYDFYIAFRETLPKEEILNFIR------------KDPSNTKLLELAETPDAF 576

Query: 595 DKLALVWFIKGLTECQYVGILKTQRYQTYEIVEKIIWRGI 634
           DK+AL+ F++ +   + +G++K Q  ++Y++VEK +WRGI
Sbjct: 577 DKVALILFMQAIFAFENMGLIKFQSTKSYDLVEKCVWRGI 616


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.321    0.139    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,006,862
Number of Sequences: 60738
Number of extensions: 1484812
Number of successful extensions: 4505
Number of sequences better than 1.0e-05: 1
Number of HSP's better than  0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 4499
Number of HSP's gapped (non-prelim): 1
length of query: 634
length of database: 30,389,216
effective HSP length: 113
effective length of query: 521
effective length of database: 23,525,822
effective search space: 12256953262
effective search space used: 12256953262
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)