ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3553 suspect: HSP S KOG4643 Function unknown Uncharacterized coiled-coil protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3553 1240135 1244142 1336
(1336 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein 77 1e-13
YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115 73 3e-12
7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related... 73 3e-12
Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 71 1e-11
Hs19923757 [S] KOG4725 Uncharacterized conserved protein 71 1e-11
SPCC645.05c [Z] KOG0161 Myosin class II heavy chain 70 2e-11
YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein 68 1e-10
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 67 1e-10
CE02790 [T] KOG0976 Rho/Rac1-interacting serine/threonine kinase... 67 2e-10
Hs12667788 [Z] KOG0161 Myosin class II heavy chain 67 2e-10
7291892 [Z] KOG0161 Myosin class II heavy chain 66 4e-10
Hs11321579 [Z] KOG0161 Myosin class II heavy chain 65 6e-10
SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 65 7e-10
Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein 65 7e-10
Hs11342672 [Z] KOG0161 Myosin class II heavy chain 64 1e-09
CE26070 [Z] KOG0613 Projectin/twitchin and related proteins 64 1e-09
Hs4502443 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 64 2e-09
CE27133 [Z] KOG0161 Myosin class II heavy chain 64 2e-09
CE20196 [Z] KOG0161 Myosin class II heavy chain 62 5e-09
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 61 1e-08
YIL149c [S] KOG4674 Uncharacterized conserved coiled-coil protein 61 1e-08
SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil p... 61 1e-08
Hs15313972 [Z] KOG0161 Myosin class II heavy chain 61 1e-08
Hs7669506 [Z] KOG0161 Myosin class II heavy chain 60 2e-08
Hs8923940 [Z] KOG0161 Myosin class II heavy chain 60 2e-08
Hs13124879 [Z] KOG0161 Myosin class II heavy chain 60 3e-08
Hs13124875 [Z] KOG0161 Myosin class II heavy chain 60 3e-08
YNL250w [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC... 59 7e-08
Hs11024712 [Z] KOG0161 Myosin class II heavy chain 59 7e-08
CE22238 [S] KOG0992 Uncharacterized conserved protein 58 9e-08
7292701_2 [S] KOG4415 Uncharacterized conserved protein 58 9e-08
7303561 [S] KOG4674 Uncharacterized conserved coiled-coil protein 58 1e-07
Hs20532997 [Z] KOG0161 Myosin class II heavy chain 57 2e-07
CE21149 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC... 57 3e-07
Hs4557773 [Z] KOG0161 Myosin class II heavy chain 56 3e-07
7294543 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-intera... 56 3e-07
SPBC3D6.04c [D] KOG4593 Mitotic checkpoint protein MAD1 56 4e-07
SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 55 6e-07
SPAC29E6.03C [U] KOG0946 ER-Golgi vesicle-tethering protein p115 55 6e-07
YLR086w [BD] KOG0996 Structural maintenance of chromosome protei... 55 7e-07
Hs22045440 [T] KOG0612 Rho-associated coiled-coil containing pro... 55 7e-07
ECU04g1000 [Z] KOG0161 Myosin class II heavy chain 55 7e-07
CE07978 [Z] KOG4280 Kinesin-like protein 55 7e-07
7290766 [K] KOG4673 Transcription factor TMF TATA element modula... 55 1e-06
CE04618 [Z] KOG0161 Myosin class II heavy chain 54 1e-06
Hs7705348 [Z] KOG0247 Kinesin-like protein 54 2e-06
Hs17978507 [Z] KOG0161 Myosin class II heavy chain 54 2e-06
Hs13124877 [Z] KOG0161 Myosin class II heavy chain 54 2e-06
CE07306 [Z] KOG0161 Myosin class II heavy chain 54 2e-06
7302958 [Z] KOG0240 Kinesin (SMY1 subfamily) 54 2e-06
Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and relat... 53 3e-06
Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription fact... 52 6e-06
Hs4505983 [R] KOG0249 LAR-interacting protein and related proteins 52 6e-06
Hs4505065 [D] KOG4593 Mitotic checkpoint protein MAD1 52 6e-06
7303314 [S] KOG0992 Uncharacterized conserved protein 52 6e-06
7292323 [S] KOG4643 Uncharacterized coiled-coil protein 52 6e-06
YKL179c [K] KOG0963 Transcription factor/CCAAT displacement prot... 52 8e-06
CE27954 [Z] KOG0613 Projectin/twitchin and related proteins 52 8e-06
>Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 742
Score = 77.4 bits (189), Expect = 1e-13
Identities = 120/503 (23%), Positives = 212/503 (41%), Gaps = 74/503 (14%)
Query: 839 ASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQA 898
AS S C S + +TE Q+L+ E+ ++ KI L +L EK E+L +
Sbjct: 152 ASSSAQSPCGSP----GMKRTESRQHLSVELADAKAKIRRL---RQELEEKTEQLLDCKQ 204
Query: 899 KLVQ-ELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEK 957
+L Q E++ L+ + A+ A + +D+ +++ + R L + +S+ ++
Sbjct: 205 ELEQMEIELKRLQQENMNLLSDARSARMY-RDELDALREKAVRVDKLESE----VSRYKE 259
Query: 958 DLVEIEALNKNVTERLFEIKRIKDREVENHPIIK---QLRDTLEGERAHFESQLALEKQK 1014
L +IE F R+++ + +N +++ L D LEG RA + LEK+
Sbjct: 260 RLHDIE----------FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN 309
Query: 1015 VSNLKAALLSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHL--QT 1072
+ LKA L + D +D KK+EEL E + + + + + HL +
Sbjct: 310 L-QLKAKLHDMEMERD----------MDRKKIEELMEENMTLEMAQKQSMDESLHLGWEL 358
Query: 1073 ECSTYRNLLSEKKHKY--NELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNT 1130
E + + LSE K +E+N L S + +L N L ++ L V + N
Sbjct: 359 EQISRTSELSEAPQKSLGHEVNE---LTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA 415
Query: 1131 KSKLKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNG----AITYIDENE 1186
LK + + +++ +E+ Q + Q QN K L K I + EN
Sbjct: 416 SKILKMEKENQRLSKKVEILENEIVQEKQS-LQNCQNLSKDLMKEKAQLEKTIETLRENS 474
Query: 1187 ILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIK 1246
IL E LN TV L++R + E V + EKE + + IK
Sbjct: 475 ERQIKILEQENEHLNQTVSSLRQR--SQISAEARVKDI----EKENKILHES------IK 522
Query: 1247 RLESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNGEDPVAL 1306
S ++K+ EK + ++ L KEK +R EE ++ ++K + L
Sbjct: 523 ETSSKLSKIEFEK-------RQIKKELEHYKEKGERAEELENELHHLEK------ENELL 569
Query: 1307 KETIVRLLKERKKLTAILKNQAE 1329
++ I L +K+ A+ + +E
Sbjct: 570 QKKITNLKITCEKIEALEQENSE 592
Score = 54.3 bits (129), Expect = 1e-06
Identities = 72/358 (20%), Positives = 148/358 (41%), Gaps = 61/358 (17%)
Query: 858 KTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSA 917
K E+++N EI+Q + + + ++ L ++ +LEK +E+ S
Sbjct: 431 KVEILEN---EIVQEKQSLQNCQNLSKDLMKEKAQLEKT------------IETLRENSE 475
Query: 918 GTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVE-IEALNKNVTERLFEI 976
K E N+ +++++ + R + A K I K K L E I+ + +++ FE
Sbjct: 476 RQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEK 535
Query: 977 KRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVK 1036
++IK +E+E++ + + LE E H E + L ++K++NLK
Sbjct: 536 RQIK-KELEHYKEKGERAEELENELHHLEKENELLQKKITNLK----------------- 577
Query: 1037 PAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVA 1096
+ +K+E L+ E +E L + + L ++
Sbjct: 578 ----ITCEKIEALEQE------------------NSELERENRKLKKTLDSFKNLTFQLE 615
Query: 1097 LASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQ 1156
K+ +QL N LR ++SL K +S ++L+ + + ++ + + G E+ +
Sbjct: 616 SLEKENSQLDEENLELRRNVESL-----KCASMKMAQLQLENKELESEKEQLKKGLELLK 670
Query: 1157 SSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTL 1214
+S + + + + L N + EN L E++ L M LQ+ ++ L
Sbjct: 671 ASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 728
>YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1790
Score = 72.8 bits (177), Expect = 3e-12
Identities = 117/558 (20%), Positives = 241/558 (42%), Gaps = 93/558 (16%)
Query: 811 KKGKDELHFDPEKCED-VTQFRKEYLAL-RASISKDDTCSSSLVNEDLNKTEVIQNLTSE 868
+KG + + +K ED + + K+ AL R + ++ C + + ++ +K+ V ++
Sbjct: 845 EKGLETILSQKKKAEDGINKMGKDLFALSREMQAVEENCKN--LQKEKDKSNVNHQKETK 902
Query: 869 IIQSEM--KIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVN 926
++ ++ KI + IN L E + + +K + + L+E K F + A++
Sbjct: 903 SLKEDIAAKITEIKAINENLEEMKIQCNNL-SKEKEHISKELVEYKSRFQSHDNLVAKLT 961
Query: 927 NKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDR-EVE 985
K K+ + N K + A + LI VE+ E N+ ++ + + K+ ++E
Sbjct: 962 EKLKSLANNY-----KDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIE 1016
Query: 986 NHPI---IKQLRDTL--------------EGERAHFESQLALEKQKVSNLKAALLSRHGK 1028
I I+QL+ T+ + + +ESQ++L K+K+ A
Sbjct: 1017 RGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTA------- 1069
Query: 1029 NDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKY 1088
ND E V + L K EEL+AEL++ Y+NL
Sbjct: 1070 ND--ENVNKISELT-KTREELEAELAA---------------------YKNLK------- 1098
Query: 1089 NELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSI 1148
NEL +K+ + K +++ HL+ + LE K ++ TK +L + ++ ++
Sbjct: 1099 NELETKLETSEKALKEVKENEEHLKEEKIQLE----KEATETKQQLNSLRANLESLEK-- 1152
Query: 1149 SGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQ 1208
E + + +YE+ K + N I+ +++ EI + N+ ++K N +
Sbjct: 1153 ----EHEDLAAQLKKYEEQIANKERQYNEEISQLND-EITSTQQENESIKKKNDELEGEV 1207
Query: 1209 RRIKTLTKLETNVGPLSV------FCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADM 1262
+ +K+ ++ ++N+ + E +K + + L IK +ES K+ + +
Sbjct: 1208 KAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDEC 1267
Query: 1263 TAK---VKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNGEDPVALK-ETIVRLLKERK 1318
K V +LE L S++K +Y E +S+K+ + + ++ E I L K ++
Sbjct: 1268 NFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKITNLSKAKE 1327
Query: 1319 K----LTAILKNQAESKE 1332
K L+ + K +E ++
Sbjct: 1328 KSESELSRLKKTSSEERK 1345
Score = 70.9 bits (172), Expect = 1e-11
Identities = 159/809 (19%), Positives = 310/809 (37%), Gaps = 145/809 (17%)
Query: 651 LESPSNNFISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIERQIEDGN 710
LE +S+ +A + + K+ KD L+ S++ + + + ++++ + N
Sbjct: 844 LEKGLETILSQKKKAEDGINKMGKD-LFALSREMQAVEENCKN--------LQKEKDKSN 894
Query: 711 VSEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNRLEPDANTLSAHALPSSVI 770
V+ Q+ T S+ + D+ K+ E E L N L + +S +
Sbjct: 895 VNH---QKETKSL--KEDIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSR 949
Query: 771 GVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPEKCEDVTQF 830
+ + + S N + A+ + I+ E + + +L K + ++Q
Sbjct: 950 FQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQE 1009
Query: 831 RKEYLALRASISKD-DTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASL-------VGI 882
++ + R SI K+ + ++ + + K E+I S + E +I+ L
Sbjct: 1010 KENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTA 1069
Query: 883 NHQLREKLEELEKIQAKLVQELDTVL-----LESKGSFSAGTAKEAEVNN---------- 927
N + K+ EL K + +L EL LE+K S KE + N
Sbjct: 1070 NDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQL 1129
Query: 928 -KDKTES---INNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIK-RIKDR 982
K+ TE+ +N+ +A +SL H L ++++K +I + E + ++ I
Sbjct: 1130 EKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITST 1189
Query: 983 EVENHPIIKQLRDTLEGE----RAHFESQLALEKQKVSNLKAALLSRHGKNDINE----E 1034
+ EN I K+ D LEGE ++ E Q L+K ++ L + KN+ NE E
Sbjct: 1190 QQENESI-KKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLE 1248
Query: 1035 VKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSK 1094
+ + K++ELQ E + + K + + S Y L E + EL++K
Sbjct: 1249 SIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAK 1308
Query: 1095 VA---LASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQ-------NT 1144
+ ++ L ++L L+ S+ N + +L+ + Q
Sbjct: 1309 TTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKE 1368
Query: 1145 QRSISGGSE-------------------VQQSSLTPAQYEQNAPKKLPK---SNGAITYI 1182
++ ++ GS +Q + A+ N +L K SN +
Sbjct: 1369 RKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEE 1428
Query: 1183 DENEI--LTKDILN--DEVRKLNMTVLDLQRRIK---------------TLTKLETNVGP 1223
+N I L +IL+ D++ + + +L ++R K + K+E +
Sbjct: 1429 KQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKK 1488
Query: 1224 LSVFCEKEKLSIRDVVDRLHWIKRLEST-------------------------------- 1251
L KEK + + + K+LEST
Sbjct: 1489 LEEESSKEKAELEKSKEMM---KKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEED 1545
Query: 1252 IAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKV--------DKPRPNGEDP 1303
I + +EK+D+ +++ + E + + K K+ + S+ + V +K R N E+
Sbjct: 1546 IKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEEN 1605
Query: 1304 VALKETIVRLLKERKKLTAILKNQAESKE 1332
LK + + +E K A +K+ E KE
Sbjct: 1606 TVLKSKLEDIERELKDKQAEIKSNQEEKE 1634
>7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1690
Score = 72.8 bits (177), Expect = 3e-12
Identities = 132/612 (21%), Positives = 246/612 (39%), Gaps = 45/612 (7%)
Query: 676 ELYNGSKQKRRTRGSAPDSEGSKKPLIERQIEDGNVSEKTPQEPTTSIPGETDVNEKVLE 735
E+ K+ + R DS+ S+ L +G EK+ +E ++ + +V + E
Sbjct: 1017 EMLQKEKELQELRQQLQDSQDSQTKLKA----EGERKEKSFEESIKNL--QEEVTKAKTE 1070
Query: 736 PIEDIEMLPTFISSSNRLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPD 795
+E T I N H + +K L T+ + +
Sbjct: 1071 NLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISAT 1130
Query: 796 NAQASTEIETNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSL-VNE 854
NA+ ST +E + K E + E E E L + + K++ + L ++E
Sbjct: 1131 NAELSTVLEVLQAE----KSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDE 1186
Query: 855 DLNKTEVIQNLTSEIIQSEMKIAS--------LVGINHQLREKLEELEKIQAKLVQELDT 906
K E ++ + QSE K+ L I L+E L++ K + +LVQ L+
Sbjct: 1187 RQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQE-LQDSVKQKEELVQNLEE 1245
Query: 907 VLLESKGSFSAGTAK--EAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEA 964
+ ES A K E+ V ++KT + Q ++ L + K EK L E A
Sbjct: 1246 KVRESSSIIEAQNTKLNESNVQLENKTSCLKETQ--DQLLES------QKKEKQLQEEAA 1297
Query: 965 LNKNVTERLFEIKR-IKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALL 1023
+++ E IKD V+ ++K L + L+ + ++Q A K+ LL
Sbjct: 1298 KLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQE-----LL 1352
Query: 1024 SRHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSE 1083
+ +N+ N + + A + KL++L+ + + N K LQ + +L
Sbjct: 1353 VKSQENEGNLQGESLAVTE--KLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLES 1410
Query: 1084 KKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKL----KPSSY 1139
+K +NE+ K+ A ++ L+ + L +L L+ ++ + + K K + +
Sbjct: 1411 QKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF 1470
Query: 1140 DSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRK 1199
D+Q + +S+ A EQ ++ + A+ ++ + + R+
Sbjct: 1471 DTQLAEYQKVIDEMDDAASVKSALLEQ-LQNRVAELETALRQANDAQKTAYLETKELRRQ 1529
Query: 1200 LNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEK 1259
L L+ R + +L K + N G S + +++ D+ L I L S IA M +
Sbjct: 1530 LESLELEKSREVLSL-KAQMN-GASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKN 1587
Query: 1260 ADMTAKVKDLET 1271
+ AKV+ LET
Sbjct: 1588 DALKAKVQTLET 1599
Score = 63.5 bits (153), Expect = 2e-09
Identities = 119/632 (18%), Positives = 242/632 (37%), Gaps = 75/632 (11%)
Query: 735 EPIEDIEMLPTFISSSNRLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQP 794
E ++ E ++ +LE + L A ++ + ++ + S E L
Sbjct: 679 ELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQL-- 736
Query: 795 DNAQASTEIETNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISK----------- 843
A + E + K+ + E+H K ++ TQ E + S+ K
Sbjct: 737 ----ALKQNELEDFQKKQSESEVHLQEIKAQN-TQKDFELVESGESLKKLQQQLEQKTLG 791
Query: 844 DDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQE 903
+ ++L K +I+ E+ Q + K A ++ +LE+L++ A +E
Sbjct: 792 HEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEE 851
Query: 904 LDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIE 963
+ + S +AE + + +N +A+ K L AA+G L + +K
Sbjct: 852 GSKTVAKLHDEISQ-LKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKS----- 905
Query: 964 ALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFE-SQLALEKQKVSNLKAAL 1022
L +I ++K E + +E + E + ALEK K
Sbjct: 906 ------GHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVN----KEYA 955
Query: 1023 LSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLS 1082
SR +D+ ++VK + L AEL + R + A H E +T
Sbjct: 956 ESRAEASDLQDKVKEIT-------DTLHAELQAERSSSSALHTKLSKFSDEIAT------ 1002
Query: 1083 EKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQ 1142
+ EL SK S++ Q LR +LQ +D +K+ + + K K +
Sbjct: 1003 ----GHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIK 1058
Query: 1143 NTQRSISGGSEVQQSSLTPAQYE-QNAPKKLPKSNGAITY------IDENEILTKDILND 1195
N Q ++ T Q ++ ++L +N + + D +I L +
Sbjct: 1059 NLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVE 1118
Query: 1196 EVRKLNMTVLDLQRRIKTL------TKLETNVGPLSVFCEKEKLSIRDVVDRLHWIK-RL 1248
++ N + + T+ K ETN +F + ++ +++++ IK L
Sbjct: 1119 AIQVANANISATNAELSTVLEVLQAEKSETN-HIFELFEMEADMNSERLIEKVTGIKEEL 1177
Query: 1249 ESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQ----KVDKPRPNGEDPV 1304
+ T ++ + K ++LE L Q+++ + ++ S S+ ++ + +D V
Sbjct: 1178 KETHLQLDERQ----KKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSV 1233
Query: 1305 ALKETIVRLLKERKKLTAILKNQAESKERDPN 1336
KE +V+ L+E+ + ++ + +K + N
Sbjct: 1234 KQKEELVQNLEEKVRESSSIIEAQNTKLNESN 1265
>Hs4758200 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 2871
Score = 70.9 bits (172), Expect = 1e-11
Identities = 140/770 (18%), Positives = 313/770 (40%), Gaps = 103/770 (13%)
Query: 622 SNDICNIRNYESVEVHHLQKLPPRLRYLELESPSNNFISKPLRANNRVEKLR------KD 675
+ ++ N+RN E++ + K + ++ E S N ++ R + L+ D
Sbjct: 1200 NEEMSNLRNKYETEIN-ITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLND 1258
Query: 676 ELYNGSKQKRRTRGSAPDSEGSKKPLIER----QIEDGNVSEKTPQEPTTSIPGETDVNE 731
+ ++Q+RR +A + ++++ +IE V ++ ++ + +
Sbjct: 1259 SILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAK 1318
Query: 732 KVLEPIEDIEMLPT-FISSSNRLEPDANTLSA--HALPSSVIGVKKQ------PSLTTVN 782
+ + ++IE L F + R N LS + +I +K Q + TT++
Sbjct: 1319 TIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIH 1378
Query: 783 KFPASFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASIS 842
+ E AQ N S++ K + + E++ + ++ +A+ S
Sbjct: 1379 QLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGS 1438
Query: 843 KDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQ 902
+ L ++ +V Q T E ++ + SL +++K +E+E+++ + +
Sbjct: 1439 EVSQRKQQL---EVELRQVTQMRTEESVRYKQ---SLDDAAKTIQDKNKEIERLKQLIDK 1492
Query: 903 EL-DTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLT-------------AAH 948
E D LE + + + + N TE+IN + +E+ LT
Sbjct: 1493 ETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVK 1552
Query: 949 GKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQL 1008
+ I++ + L E++ + V E E+ R+K E+ K+L + LEG R + Q
Sbjct: 1553 DQDITRFQNSLKELQLQKQKVEE---ELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQA 1609
Query: 1009 ALEKQKVSNL-----KAALLSRHGKNDINEEVKPAAPLDG---------KKLEELQAELS 1054
K++NL +A+++ + ++D+ ++ LDG ++L L +E+
Sbjct: 1610 I----KITNLTQQLEQASIVKKRSEDDLRQQ---RDVLDGHLREKQRTQEELRRLSSEVE 1662
Query: 1055 STRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRN 1114
+ R + + K ++ + +K NE SK+ +
Sbjct: 1663 ALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNE--SKIEI----------------E 1704
Query: 1115 KLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTPAQYE-QNAPKKLP 1173
+LQSL + ++K + +L+ + + +R S + +++ + + Q + +
Sbjct: 1705 RLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTL 1764
Query: 1174 KSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRI--------KTLTKLETNVGPLS 1225
+ G I + ++ L E+ K L+ RI + + + E+ + +
Sbjct: 1765 ELQGLINDLQRE----RENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIK 1820
Query: 1226 VFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEE 1285
V E++K ++ + D L+ R +ST+ K + + + ++ L+Q K + R EE
Sbjct: 1821 VL-EQDKARLQRLEDELN---RAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEE 1876
Query: 1286 YSSKSQKVDKPRPNGE-DPVALKETIVRLLKERKKLTAILKNQAESKERD 1334
+K++ R E + +L+ I RL E K++ + + E R+
Sbjct: 1877 ---AIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRE 1923
>Hs19923757 [S] KOG4725 Uncharacterized conserved protein
Length = 990
Score = 70.9 bits (172), Expect = 1e-11
Identities = 107/541 (19%), Positives = 217/541 (39%), Gaps = 62/541 (11%)
Query: 821 PEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLV 880
P+ + + Q +E L A + + S+ + + + +NL E ++ +
Sbjct: 347 PDANQQLQQAMEERAQLEAHLGQ---VMESVRQLQMERDKYAENLKGESAMWRQRMQQMS 403
Query: 881 GINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAR 940
H LRE+ E VQEL+T L E + + E + + + E
Sbjct: 404 EQVHTLREEKE----CSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEH 459
Query: 941 -EKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEG 999
K L G+L ++V+ D + LN+ ERL E++R + E +Q+ +T++
Sbjct: 460 LRKELEGLAGQLQAQVQ-DNEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQN 518
Query: 1000 ERAHFESQLALE---KQKVSNLKAALLSRHGKN-DINEEVKPAAPLD---GKKLEELQAE 1052
+R L+ K++++ L++ + +N +I ++ + GKKL ELQ +
Sbjct: 519 DRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEK 578
Query: 1053 LSSTRLYARAQHNAAK-----------HLQTECSTYRNLLSEKKHKYNELNSKVALASKQ 1101
LS + + A+ HLQ + Y+ L SEK+ +N+L + L +
Sbjct: 579 LSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQL 638
Query: 1102 CAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLK----------PSSYDSQNTQRSISGG 1151
Q A Q L++ ++ + T+ + P D + +
Sbjct: 639 QQQEAQGKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREEEEDEE 698
Query: 1152 SEVQQSSLTPAQYEQNAPKKLPKS-------NGAITYIDENEILTKDILNDE---VRKLN 1201
E +++ P Q + P+ L N A+ +E + + L ++ R+L
Sbjct: 699 EEEEEAVAVP-QPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLA 757
Query: 1202 MTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKAD 1261
+ Q+ + G C + +++ ++ +L+S ++ EKAD
Sbjct: 758 HLLASAQKEPEAAAPAPGTGG--DSVCGETHRALQGAME------KLQSRFMELMQEKAD 809
Query: 1262 MTAKVKDLETALSQSKEKVDRYEEYSS--KSQKVDKPRPNGEDPVALKETIVRLLKERKK 1319
+ +V++LE Q + D EY + +SQ+ + E +E I RL +++++
Sbjct: 810 LKERVEELEHRCIQLSGETDTIGEYIALYQSQRAVLKERHREK----EEYISRLAQDKEE 865
Query: 1320 L 1320
+
Sbjct: 866 M 866
>SPCC645.05c [Z] KOG0161 Myosin class II heavy chain
Length = 1526
Score = 70.1 bits (170), Expect = 2e-11
Identities = 118/564 (20%), Positives = 246/564 (42%), Gaps = 93/564 (16%)
Query: 825 EDVTQFRKEYLA-LRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGIN 883
E++ + +E LA + S S+ + +L E + ++ L SE+++ K+ +L+
Sbjct: 879 EEILRRTQERLANIEDSFSETKQQNENLQRESASLKQINNELESELLEKTSKVETLLSEQ 938
Query: 884 HQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKT--ESINNEQARE 941
++L+EKL EK EL+++ + + + +++AE N + K+ E+I + A
Sbjct: 939 NELKEKLSLEEKDLLDTKGELESL----RENNATVLSEKAEFNEQCKSLQETIVTKDAEL 994
Query: 942 KSLTAAHGKLISKVEKDLVEIEALNKNVTERLFE--------IKRIKDREVENHPIIKQL 993
LT K IS + ++ E+ N+ + E+ + +KR+K E EN +I +
Sbjct: 995 DKLT----KYISDYKTEIQEMRLTNQKMNEKSIQQEGSLSESLKRVKKLERENSTLISDV 1050
Query: 994 RDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGKKLEELQAEL 1053
S L +K+++S LK + N++ E+V D K+L +L+ EL
Sbjct: 1051 ------------SILKQQKEELSVLKG--VQELTINNLEEKVN-YLEADVKQLPKLKKEL 1095
Query: 1054 SS----TRLYARAQHNAAKHLQT---ECSTYRNLLSEKKHKYNELNSKVALASKQCAQLR 1106
S +LY + Q K L+ EC L+++ E ++ AS + +L+
Sbjct: 1096 ESLNDKDQLY-QLQATKNKELEAKVKECLNNIKSLTKELENKEEKCQNLSDASLKYIELQ 1154
Query: 1107 STNAHLRNKLQSLEDVVSK---------------------------ISSNTKSKLKPSSY 1139
+ +L K+ LE+ K ++ N +S L+ S+
Sbjct: 1155 EIHENLLLKVSDLENYKKKYEGLQLDLEGLKDVDTNFQELSKKHRDLTFNHESLLRQSAS 1214
Query: 1140 DSQNTQRSISGGSEVQQ--SSLTPAQYEQNAPK--KLPKSNGAITYIDENEILTKDILND 1195
+ + S ++ SSLT Q + +PK K+P+ IT + D
Sbjct: 1215 YKEKLSLASSENKDLSNKVSSLT-KQVNELSPKASKVPELERKITNLMHEYSQLGKTFED 1273
Query: 1196 EVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKM 1255
E RK + D + ++LE+ K ++ + V++ + + L S + +
Sbjct: 1274 EKRKALIASRDNEELRSLKSELESK--------RKLEVEYQKVLEEVKTTRSLRSEVTLL 1325
Query: 1256 ANEKAD---MTAKVKDLETALSQSKEK----VDRYEEYSSKSQKVDKPRPNGED----PV 1304
N+ AD + +K+ ++E L ++++ +D ++ ++ ++ + RP+G++ V
Sbjct: 1326 RNKVADHESIRSKLSEVEMKLVDTRKELNSALDSCKKREAEIHRLKEHRPSGKENNIPAV 1385
Query: 1305 ALKETIVRLLKERKKLTAILKNQA 1328
E +++ + +RK + + + A
Sbjct: 1386 KTTEPVLKNIPQRKTIFDLQQRNA 1409
>YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1875
Score = 67.8 bits (164), Expect = 1e-10
Identities = 98/504 (19%), Positives = 206/504 (40%), Gaps = 59/504 (11%)
Query: 848 SSSLVNEDLNKTEVIQNLTSEII-QSEMKIASLVGINHQLREKLEELEKIQAKLVQELDT 906
+ L +++ + +Q + SE + +++ I +L L ++EEL+K ++EL T
Sbjct: 557 ADKLESKEKKSKQSLQKIESETVNEAKEAIITLKSEKMDLESRIEELQKE----LEELKT 612
Query: 907 VLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALN 966
+ S+S T K+ +D + + Q R +T + +S + K++ ++
Sbjct: 613 SVPNEDASYSNVTIKQLTETKRDLESQVQDLQTRISQITRESTENMSLLNKEIQDLYDSK 672
Query: 967 KNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRH 1026
+++ +L + K + E ++ D + E +++ L+ +L +
Sbjct: 673 SDISIKLGKEKSSRILAEERFKLLSNTLDLTKAENDQL-------RKRFDYLQNTILKQD 725
Query: 1027 GK--NDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEK 1084
K +NE V + KL ++ EL L + + HL+ N LS +
Sbjct: 726 SKTHETLNEYVSCKS-----KLSIVETEL----LNLKEEQKLRVHLEKNLKQELNKLSPE 776
Query: 1085 KHKYNELNSKVALASKQCAQ-LRSTNAHLRNKLQSLEDVVSKISSNTKSK---LKPSSYD 1140
K + +++ K+ L T + K+ LED +S++ T K +K D
Sbjct: 777 KDSLRIMVTQLQTLQKEREDLLEETRKSCQKKIDELEDALSELKKETSQKDHHIKQLEED 836
Query: 1141 SQNT----QRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDE 1196
+ + Q I + +S +T +Q +KL + + L K+I D+
Sbjct: 837 NNSNIEWYQNKIEALKKDYESVITSVDSKQTDIEKLQY---------KVKSLEKEIEEDK 887
Query: 1197 VRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIK--------RL 1248
+R V+D +T+ N L EK K+++ D ++ K L
Sbjct: 888 IRLHTYNVMD-----ETI-----NDDSLRKELEKSKINLTDAYSQIKEYKDLYETTSQSL 937
Query: 1249 ESTIAKMANEKADMTAKVKDLETALSQSKEKVDRY-EEYSSKSQKVDKPRPNGEDPVALK 1307
+ T +K+ D T ++K+L + ++K+ E+ + + ++D + E A
Sbjct: 938 QQTNSKLDESFKDFTNQIKNLTDEKTSLEDKISLLKEQMFNLNNELDLQKKGMEKEKADF 997
Query: 1308 ETIVRLLKERKKLTAILKNQAESK 1331
+ + +L+ K +K++ ESK
Sbjct: 998 KKRISILQNNNKEVEAVKSEYESK 1021
Score = 62.8 bits (151), Expect = 4e-09
Identities = 201/1108 (18%), Positives = 419/1108 (37%), Gaps = 142/1108 (12%)
Query: 256 SKGSAAVPAAPKTKNKTDSQVSKIANEIQNSNKS----RISKANSPIQRTTTTTSNIPSE 311
++ A+ K +S++ ++ E++ S S +N I++ T T ++ S+
Sbjct: 580 NEAKEAIITLKSEKMDLESRIEELQKELEELKTSVPNEDASYSNVTIKQLTETKRDLESQ 639
Query: 312 AKELYNMLS--SRLKRRNV---------LFDKKGTINSENNDKTGASVKVE------SSH 354
++L +S +R N+ L+D K I+ + + + + E S+
Sbjct: 640 VQDLQTRISQITRESTENMSLLNKEIQDLYDSKSDISIKLGKEKSSRILAEERFKLLSNT 699
Query: 355 VEIIGSKRDHTHTSFMELPSMQATIADLAKTTSLVKENSAQIEVDRNLIGPERSRKNEKE 414
+++ ++ D F L + + +KT + E + L E N KE
Sbjct: 700 LDLTKAENDQLRKRFDYLQN--TILKQDSKTHETLNE---YVSCKSKLSIVETELLNLKE 754
Query: 415 FQDLETRTSSPAKESL--ASPSADTPERKVPQLDLTSPSFDSTPGVTEKMDLKEVPSPEY 472
Q L K+ L SP D+ V QL + T K K++ E
Sbjct: 755 EQKLRVHLEKNLKQELNKLSPEKDSLRIMVTQLQTLQKEREDLLEETRKSCQKKIDELED 814
Query: 473 PSSAGQAVQQSESSQISHVIQQAEGADSGSHHGIQVESSELNIPTIFEKKDNPQAASASG 532
S + E+SQ H I+Q E ++ + Q + L KKD ++
Sbjct: 815 ALSE----LKKETSQKDHHIKQLEEDNNSNIEWYQNKIEAL-------KKDYESVITS-- 861
Query: 533 TFHHVDEKQSTEETAKLLALXXXXXXXXXXXXXXXHYVGDFQLLN-TMKARMVGPKVAKW 591
VD KQ+ E + + V D + + +++ + K+
Sbjct: 862 ----VDSKQTDIEKLQYKVKSLEKEIEEDKIRLHTYNVMDETINDDSLRKELEKSKINLT 917
Query: 592 KAFNKSK-FKDLMKYLIAEHTPLAARSDVSCSNDICNIRNYESVEVHHLQKLPPRLRYLE 650
A+++ K +KDL + ++ D S + I+N + K+ +
Sbjct: 918 DAYSQIKEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKNLTDEKTSLEDKISLLKEQMF 977
Query: 651 LESPSNNFISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIERQIEDGN 710
+ + K + K R L N +K+ + SK I+ ++
Sbjct: 978 NLNNELDLQKKGMEKEKADFKKRISILQNNNKEVEAVKSEYE----SKLSKIQNDLDQQT 1033
Query: 711 VSEKTPQEP-TTSIPGETDVNEKVLEPIEDIE----MLPTFISSSNRLEPDANTLSAHAL 765
+ T Q + DV++ + E E + + T S ++LE +A + +
Sbjct: 1034 IYANTAQNNYEQELQKHADVSKTISELREQLHTYKGQVKTLNLSRDQLE-NALKENEKSW 1092
Query: 766 PSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPEKCE 825
S + +Q L+ S +N L D Q T + NS G P
Sbjct: 1093 SSQKESLLEQLDLSNSRIEDLSSQNKLLYDQIQIYTAADKEVNNSTNG-------PGLNN 1145
Query: 826 DVTQFRKE--YLALRASISKDDTCSSSLVNEDLNKTEV-IQNLTSEIIQSEMKI---ASL 879
+ R+E L + ++++ D + ++ + ++ +V +Q+ +++ S ++ +S+
Sbjct: 1146 ILITLRRERDILDTKVTVAERD---AKMLRQKISLMDVELQDARTKLDNSRVEKENHSSI 1202
Query: 880 VGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQA 939
+ + + EKL +L + +E+ + +++ E+ NN
Sbjct: 1203 IQQHDDIMEKLNQLNLL------------------------RESNITLRNELENNNN--- 1235
Query: 940 REKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEG 999
++K L + KL V E+ AL ++ E+ E+K K+ E H K+ +D LE
Sbjct: 1236 KKKELQSELDKLKQNVAPIESELTALKYSMQEKEQELKLAKE---EVHRWKKRSQDILEK 1292
Query: 1000 ERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLY 1059
S + ++ NLK L ++ + EE + + Q L +++L
Sbjct: 1293 HEQLSSSDYEKLESEIENLKEELENKERQGAEAEEKF------NRLRRQAQERLKTSKLS 1346
Query: 1060 ARAQHNAAKHLQTECSTYRNLLSEKKHKYNEL-NSKVALASKQCAQLRSTNAHLRNKLQS 1118
+ L+ + N LSE + EL N+KVA + Q +R +
Sbjct: 1347 QDSLTEQVNSLRDAKNVLENSLSEANARIEELQNAKVAQGNNQLEAIRKLQEDAEKASRE 1406
Query: 1119 LEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGA 1178
L+ + + +++ +S + + + + I ++QQ + EQN + +S
Sbjct: 1407 LQAKLEESTTSYESTINGLNEEITTLKEEIEKQRQIQQQLQATSANEQNDLSNIVES--M 1464
Query: 1179 ITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDV 1238
+E++I + ++ +++N +L+ Q R+ P ++ E+ K
Sbjct: 1465 KKSFEEDKI---KFIKEKTQEVNEKILEAQERLNQ---------PSNINMEEIKKK---- 1508
Query: 1239 VDRLHWIKRLESTIAKMANEKADMTAKVKDLET------ALSQSKEKVDRYEEYSSK-SQ 1291
W E +++ E + K L T + + KE++++ E+ K +
Sbjct: 1509 -----WESEHEQEVSQKIREAEEALKKRIRLPTEEKINKIIERKKEELEK--EFEEKVEE 1561
Query: 1292 KVDKPRPNGEDPVALKETIVRLLKERKK 1319
++ +GE V L++ + ++E++K
Sbjct: 1562 RIKSMEQSGEIDVVLRKQLEAKVQEKQK 1589
Score = 60.8 bits (146), Expect = 1e-08
Identities = 101/453 (22%), Positives = 190/453 (41%), Gaps = 39/453 (8%)
Query: 648 YLELESPSNNFISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIER--Q 705
Y +LES N K N + +E +N + +R+ + S+ S+ L E+
Sbjct: 1301 YEKLESEIENL--KEELENKERQGAEAEEKFN--RLRRQAQERLKTSKLSQDSLTEQVNS 1356
Query: 706 IEDG-NVSEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNRLEPDANTL---S 761
+ D NV E + E I E N KV + +E + + + + S
Sbjct: 1357 LRDAKNVLENSLSEANARI--EELQNAKVAQGNNQLEAIRKLQEDAEKASRELQAKLEES 1414
Query: 762 AHALPSSVIGVKKQPSLTTVNKF---PASFENGLQPDNAQASTEIETNEGNSKKG--KDE 816
+ S++ G+ ++ +TT+ + + LQ +A ++ + KK +D+
Sbjct: 1415 TTSYESTINGLNEE--ITTLKEEIEKQRQIQQQLQATSANEQNDLSNIVESMKKSFEEDK 1472
Query: 817 LHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVN---EDLNKTEVIQNL--TSEIIQ 871
+ F EK ++V + + L + +++ + + E ++ EV Q + E ++
Sbjct: 1473 IKFIKEKTQEVNE---KILEAQERLNQPSNINMEEIKKKWESEHEQEVSQKIREAEEALK 1529
Query: 872 SEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKT 931
+++ + IN + K EELEK + V+E +E G K+ E ++K
Sbjct: 1530 KRIRLPTEEKINKIIERKKEELEKEFEEKVEER-IKSMEQSGEIDVVLRKQLEAKVQEKQ 1588
Query: 932 ESINNE---QAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHP 988
+ + NE + +E+ H IS E+D + E ++ E E++ IK + +
Sbjct: 1589 KELENEYNKKLQEELKDVPHSSHISDDERDKLRAEIESRLREEFNNELQAIKKKSFDEGK 1648
Query: 989 IIKQLRDTL-EGERAHFESQLALEKQK-------VSNLKAALLSRHGKNDINEEVKPAAP 1040
++ TL E + A ESQL+ KQ V+N++ LL K + N
Sbjct: 1649 QQAMMKTTLLERKLAKMESQLSETKQSAESPPKSVNNVQNPLLGLPRKIEENSNSPFNPL 1708
Query: 1041 LDGKKLEELQAELSSTRLYARAQHNAAKHLQTE 1073
L G+KL +L ++ SS + KHLQ +
Sbjct: 1709 LSGEKLLKLNSKSSSGGFNPFTSPSPNKHLQND 1741
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 67.4 bits (163), Expect = 1e-10
Identities = 147/737 (19%), Positives = 283/737 (37%), Gaps = 153/737 (20%)
Query: 660 SKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIERQIEDGNVS-EKTPQE 718
S R N+ ++ RK+E ++K T +E K +E++ + N EKT +E
Sbjct: 425 SPSCRENDSIQS-RKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKE 483
Query: 719 PTTSIPGETDVNEKVLEPIEDIEMLPTFISSSN---------------RLEPDANTLSAH 763
+ E + + V + +E + N LE D N+L
Sbjct: 484 ----LEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQ 539
Query: 764 ALPSSVIGVKKQPSLTTVNKFPASFE--NGLQPDNAQASTEIETNEGNSKKGKDELHFDP 821
Q S VN+ + N L + + + + S K +L +
Sbjct: 540 LEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNN 599
Query: 822 EKCEDVT--------QFRKEYLALRASIS---KDDTCSSSLVNEDLNKTEVIQNLTSEII 870
+D + KE++ L++++ +D T S ++N+ + I L ++
Sbjct: 600 RDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGR---ICGLEEDLK 656
Query: 871 QSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDK 930
++ +A + QL+E+ +LEK ++ + ++ L + S ++ E +K
Sbjct: 657 NGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSL-----EQEEAEHKAT 711
Query: 931 TESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKR------------ 978
+ ++ +S+ A + + ++EK L+E L + V L E ++
Sbjct: 712 KARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQS 771
Query: 979 -------IKDREVENHPIIKQLRDTLEGE---RAHFESQLALEKQKVSNLKAALLSRHGK 1028
+K ++V N + + L +E E R ++ L ++ Q+V+ LK + +
Sbjct: 772 QQKINELLKQKDVLNEDV-RNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQE 830
Query: 1029 NDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKY 1088
N+ E+K LE+ AEL R A Q K LQ + + + K +
Sbjct: 831 NNHLMEMK-------MNLEKQNAELRKERQDADGQ---MKELQDQLEAEQYFSTLYKTQV 880
Query: 1089 NELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSI 1148
EL ++C + L+ K Q L+D +++ + L + DS+ RSI
Sbjct: 881 RELK-------EECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKA--DSEQLARSI 931
Query: 1149 SGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQ 1208
+ QY +K+ K ++ E++ + E+ + + T+ L+
Sbjct: 932 A-----------EEQYSDLEKEKIMKE------LEIKEMMARH--KQELTEKDATIASLE 972
Query: 1209 RRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKD 1268
+TLT S +A +ANEK ++ K+KD
Sbjct: 973 ETNRTLT----------------------------------SDVANLANEKEELNNKLKD 998
Query: 1269 LETALSQSKE------------KVDRYEEYSSKSQKVDKPRP--NGEDPVAL-KETIVRL 1313
++ LS+ K+ + E + K+Q V+K N ++PV +T VR
Sbjct: 999 VQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRR 1058
Query: 1314 L-KERKKLTAILKNQAE 1329
KE +KL LK++ E
Sbjct: 1059 KEKENRKLHMELKSERE 1075
>CE02790 [T] KOG0976 Rho/Rac1-interacting serine/threonine kinase Citron
Length = 1286
Score = 67.0 bits (162), Expect = 2e-10
Identities = 118/578 (20%), Positives = 240/578 (41%), Gaps = 95/578 (16%)
Query: 793 QPDNAQASTEIETNEGN--------SKKGKD------ELHFDPEKCEDVTQFRKEYLALR 838
Q D + TE+E++ S K D +LH +K E++T FR EY+
Sbjct: 141 QDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLH---DKNEELTSFRMEYVTKL 197
Query: 839 ASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQ- 897
+ +++ + + N + + E+ + ++ +++ QL E L ++
Sbjct: 198 SEANREKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEVRQLSAHFEFLTPVRK 257
Query: 898 -AKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVE 956
A ++ELD + +AK E ES+N+ + + ++LT V+
Sbjct: 258 NASKIRELD--------EYHQLSAKVIE-------ESMNDLKIKNETLTKELSDKTELVK 302
Query: 957 KDLVEIEALNKNVTERLFEIKR-IKDREVENHPIIKQLRD----TLEGER---AHFESQL 1008
E+E L + T L + ++ K EN + +Q D LE R + +
Sbjct: 303 MKNEELEDLRQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEGFDKLKQ 362
Query: 1009 ALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGKK---LEELQAELSSTRLYARAQHN 1065
LEK++ L R K ++ E++ L ++ +EEL+ ++ S + + H
Sbjct: 363 ELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEM-IKKDHE 421
Query: 1066 AAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLR----STNAHLRNKLQSLED 1121
+AK N LS + K +++ + +A +QC+ + S R ++ +
Sbjct: 422 SAK----------NELSRTQEKLDQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQCNE 471
Query: 1122 VVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQS-SLTPAQYEQNAPK-KLPKSNGAI 1179
+V +I ++ Q S+ +V+Q + A+ + A K + K
Sbjct: 472 MVVRI---------------RDLQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQE 516
Query: 1180 TYIDENEILT----KDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSI 1235
++D + L+ K ++ L +T+ +++ K V + +K+ +
Sbjct: 517 VHLDYRQELSRLAEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVK-----ADNQKVQL 571
Query: 1236 RDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYE-EYSSKSQKVD 1294
V R H K LE + ++ AD AK+++ + + S+E +R E E ++K K+D
Sbjct: 572 MLVEVRQHQEKILEENV-RLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLD 630
Query: 1295 KPRPNGEDPVALKETIVRLLKERKKLTAILKNQAESKE 1332
K E+ + K+ + + E K+L L +Q ++K+
Sbjct: 631 KL----EEELQEKK---QQIAESKELVTYLHSQIDAKQ 661
>Hs12667788 [Z] KOG0161 Myosin class II heavy chain
Length = 1960
Score = 66.6 bits (161), Expect = 2e-10
Identities = 138/633 (21%), Positives = 251/633 (38%), Gaps = 123/633 (19%)
Query: 774 KQPSLTTVNKFPASFENGLQPDNAQASTEIETNEGNSKKGK----DELHFDPEKCEDVTQ 829
K+ L V + + EN L TE+ET + K ++L + E C + +
Sbjct: 850 KEEELVKVREKQLAAENRL--------TEMETLQSQLMAEKLQLQEQLQAETELCAEAEE 901
Query: 830 FRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREK 889
R A + + + + V E+ + + +Q ++ Q+ ++ + R+K
Sbjct: 902 LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQK 961
Query: 890 LEELEKI--QAKLVQ-ELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTA 946
L+ LEK+ +AKL + E + ++LE + A K E + T ++ E+ + KSL
Sbjct: 962 LQ-LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA- 1019
Query: 947 AHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFES 1006
KL +K E + ++E ERL RE + +++ R LEG+
Sbjct: 1020 ---KLKNKHEAMITDLE-------ERL-------RREEKQRQELEKTRRKLEGDSTDLSD 1062
Query: 1007 QLALEKQKVSNLKAALLSRHGKNDI------------NEEVKPAAPLD------------ 1042
Q+A + +++ LK L + + N +K L+
Sbjct: 1063 QIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLES 1122
Query: 1043 ---------------GKKLEELQAELSSTRLYARAQHN-----------AAKHLQTECST 1076
G++LE L+ EL T AQ K L+ E T
Sbjct: 1123 ERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKT 1182
Query: 1077 YRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKP 1136
+ + E + K+++ ++A +Q Q + A+L Q+LE+ ++++ K L+
Sbjct: 1183 HEAQIQEMRQKHSQAVEELA---EQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQG 1239
Query: 1137 SSYDSQNTQRSISGGSEVQQSSLTPAQYEQN--APK------KLPKSNGAITYID-ENEI 1187
DS++ ++ + + Q + + A K +L G ++ D ++
Sbjct: 1240 KG-DSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298
Query: 1188 LTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIK- 1246
LTKD L + D Q ++ + + ++ E EK S R+ ++ K
Sbjct: 1299 LTKDF-----SALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH 1353
Query: 1247 RLESTIAKMANEKADMTAKVKD----LETALSQSKEKVDRYEEYSSKSQK-VDKPRPNGE 1301
LE IA + + ADM K++D LETA EE K QK ++ E
Sbjct: 1354 NLEKQIATLHAQVADMKKKMEDSVGCLETA-----------EEVKRKLQKDLEGLSQRHE 1402
Query: 1302 DPVA----LKETIVRLLKERKKLTAILKNQAES 1330
+ VA L++T RL +E L L +Q +S
Sbjct: 1403 EKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 1435
Score = 52.8 bits (125), Expect = 4e-06
Identities = 162/782 (20%), Positives = 301/782 (37%), Gaps = 125/782 (15%)
Query: 634 VEVHHLQKLPPRLRYLELESPSNNF---ISKPLRANNRVEKLRKDELYNGSKQKRRTRGS 690
VE QK + ELES + + + N+ EK ++D L + +
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRD-LGEELEALKTELED 1150
Query: 691 APDSEGSKKPLIERQIEDGNVSEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSS 750
DS +++ L ++ ++ N+ +KT +E + E + E + + +E L + +
Sbjct: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKT--HEAQIQEMRQKHSQAVEELAEQLEQT 1208
Query: 751 NRLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETNEGNS 810
R++ AN A + G N+ + ++ + E + E
Sbjct: 1209 KRVK--ANLEKAKQTLENERG-------ELANEVKVLLQGKGDSEHKRKKVEAQLQELQV 1259
Query: 811 KKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEII 870
K + E E + VT+ + E + +S+ D+ SS L +D + E T E++
Sbjct: 1260 KFNEGE-RVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLT-KDFSALESQLQDTQELL 1317
Query: 871 QSE--------MKIASLVGINHQLREKLEELEKIQAKLVQELDTVL-----LESKGSFSA 917
Q E K+ + + RE+LEE E+ + L +++ T+ ++ K S
Sbjct: 1318 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSV 1377
Query: 918 GTAKEAEVNNKDKTESINNEQAREKSLTAAHGKL-------------------------- 951
G + AE + + + R + AA+ KL
Sbjct: 1378 GCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSAC 1437
Query: 952 -ISKVEKDLVEIEALNKNVTERLFEIK-----RIKDREVENHPIIKQLRDTLEGERAHFE 1005
+ K +K ++ A K ++ + E + +++E + + + L + +E ++A E
Sbjct: 1438 NLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAME-QKAELE 1496
Query: 1006 SQLALEKQKVSNLKAALLSRH--GKNDINEEVKPAAPLDGK------KLEELQAELSST- 1056
L KQ + ++ + S+ GK+ ++E K L+ + +LEEL+ EL +T
Sbjct: 1497 ---RLNKQFRTEMEDLMSSKDDVGKS-VHELEKSKRALEQQVEEMKTQLEELEDELQATE 1552
Query: 1057 --RLYARAQHNAAKHLQTECSTYRNLLSEKKHK-----YNELNSKVALASKQCAQLRSTN 1109
+L A K R+ SE+K K E+ +++ KQ RS
Sbjct: 1553 DAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQ----RSMA 1608
Query: 1110 AHLRNKLQ-SLEDVVSKISSNTKSK------LKPSSYDSQNTQRSISGGSEVQQSSLTPA 1162
R KL+ L+D+ + I S K++ L+ ++ R + ++ L A
Sbjct: 1609 VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEIL--A 1666
Query: 1163 QYEQNAPKKLPKSNGAITYIDENEILT----------KDILNDEV-RKLNMTVLDLQRRI 1211
Q ++N KKL + + E +D L DE+ L L+ +
Sbjct: 1667 QAKEN-EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK- 1724
Query: 1212 KTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLET 1271
+LE + L E+E+ + + DRL K AN + D +LE
Sbjct: 1725 ---RRLEARIAQLEEELEEEQGNTELINDRL-----------KKANLQIDQINTDLNLER 1770
Query: 1272 ALSQSKEKVDRYEEYSSKSQKVDKPRPNGEDPVALKETIVRLLKERKKLTAILKNQAESK 1331
+ +Q E + E +K KV G K +I L + +L L N E+K
Sbjct: 1771 SHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDN--ETK 1828
Query: 1332 ER 1333
ER
Sbjct: 1829 ER 1830
>7291892 [Z] KOG0161 Myosin class II heavy chain
Length = 2056
Score = 65.9 bits (159), Expect = 4e-10
Identities = 112/527 (21%), Positives = 224/527 (42%), Gaps = 51/527 (9%)
Query: 805 TNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQN 864
T++ N K K++ + E+ D++Q E ++K + ++E + Q
Sbjct: 1073 TDDQNQKLLKEKKLLE-ERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQ 1131
Query: 865 LTSEIIQSEMKIASLVG-INHQLREKLEELEKIQAKLV---QELDTVLLE-SKGSFSAGT 919
E +S+ KI + V + QL E+ +++++QA+L +EL LL + S + T
Sbjct: 1132 QRQESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKAT 1191
Query: 920 AKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVE-IEALNKNVTERLFEIKR 978
A++A+ + + I + EK+ A KV +DL E +EAL + + L
Sbjct: 1192 AQKAQRELESQLAEIQEDLEAEKAARAK----AEKVRRDLSEELEALKNELLDSLDTTAA 1247
Query: 979 IKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPA 1038
++ + + L+ +LE E + E LA + K S ++ ND E ++ A
Sbjct: 1248 QQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELNSI------NDQLENLRKA 1301
Query: 1039 APLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALA 1098
+ K L+AE + R+ +++ + + ++E + K E+ +
Sbjct: 1302 KTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSEL 1361
Query: 1099 SKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSS 1158
++C +L+ ++ N+L+ E K S+ KS S+ +SQ T E QQ
Sbjct: 1362 QEKCTKLQQEAENITNQLEEAE---LKASAAVKS---ASNMESQLT--------EAQQ-- 1405
Query: 1159 LTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLN--MTVLDLQRRIKTLTK 1216
E+ +KL S+ E E L + + D+ K N + ++ +++ + K
Sbjct: 1406 ----LLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKK 1461
Query: 1217 LETNVGPLSVFCEKEKLSI--------RDVVDRLHWIKRLESTIAKMANEKADMTAKVKD 1268
L+ E+ K + R V + + RL+ + K+ +E D T +++
Sbjct: 1462 KAEEDADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEA 1521
Query: 1269 LETALSQSKEKVDRYE----EYSSKSQKVDKPRPNGEDPVALKETIV 1311
T + + ++K ++ E + S+++ + R E KET V
Sbjct: 1522 QRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKV 1568
Score = 62.8 bits (151), Expect = 4e-09
Identities = 92/500 (18%), Positives = 212/500 (42%), Gaps = 74/500 (14%)
Query: 802 EIETNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEV 861
E+ E + +DEL EK + + + +EY + +LV KT +
Sbjct: 929 EVTKQEEKLVQKEDELKQVREKLDTLAKNTQEY---------ERKYQQALVE----KTTL 975
Query: 862 IQNLTSEI---IQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAG 918
+ L +EI ++E + L+ +L + ++ELE ++ +E + VL G
Sbjct: 976 AEQLQAEIELCAEAEESRSRLMARKQELEDMMQELE---TRIEEEEERVLA------LGG 1026
Query: 919 TAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKR 978
K+ E+N +D E + E+A + L +L +K++K E AL + ++L + K+
Sbjct: 1027 EKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKK-YEEDLALTDDQNQKLLKEKK 1085
Query: 979 IKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPA 1038
+ + ERA+ SQ E+++ + A L ++H
Sbjct: 1086 LLE------------------ERANDLSQTLAEEEEKAKHLAKLKAKHEAT--------- 1118
Query: 1039 APLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALA 1098
+ EL+ L + + + + ++TE + + L+E++ + +E+ +++A
Sbjct: 1119 -------ISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKR 1171
Query: 1099 SKQCAQL-------RSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGG 1151
++ Q +T A + + LE +++I + +++ K + ++ +R +S
Sbjct: 1172 EEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAE-KAARAKAEKVRRDLSEE 1230
Query: 1152 SEVQQSSL-----TPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLD 1206
E ++ L T A ++ K+ + ++E + + +L D K + +
Sbjct: 1231 LEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELNS 1290
Query: 1207 LQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEK-ADMTAK 1265
+ +++ L K +T + E E + + ++ ++ K A + A++ K
Sbjct: 1291 INDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVK 1350
Query: 1266 VKDLETALSQSKEKVDRYEE 1285
+ ++E A S+ +EK + ++
Sbjct: 1351 LAEIERARSELQEKCTKLQQ 1370
Score = 61.6 bits (148), Expect = 8e-09
Identities = 95/480 (19%), Positives = 203/480 (41%), Gaps = 73/480 (15%)
Query: 867 SEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVN 926
S+I + ++K+A + +L+EK +L++ + +L+ L++ + + + E+++
Sbjct: 1342 SQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLT 1401
Query: 927 NKDKTESINNEQAREKSLTAAHGKLISK----VEKDLVEIEALNKNVTERLFEI----KR 978
+ + + E+ R+K ++ + I +++ L E + +N +L E+ +
Sbjct: 1402 ---EAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQE 1458
Query: 979 IKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPA 1038
IK + E+ + K+L EG++ + ALE+Q + E +
Sbjct: 1459 IKKKAEEDADLAKELE---EGKKRLNKDIEALERQ-----------------VKELIAQN 1498
Query: 1039 APLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALA 1098
LD K +++Q+EL + AQ L+ + + +L+E+K
Sbjct: 1499 DRLD-KSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEK-----------AI 1546
Query: 1099 SKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSS 1158
S+Q AQ R T + ++ VS+ K++ D +N ++++ +E+ +
Sbjct: 1547 SEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIE----DLENKRKTLQ--NELDDLA 1600
Query: 1159 LTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLE 1218
T ++N +L K+ A+ E+++ N+E+ DLQ +LE
Sbjct: 1601 NTQGTADKNV-HELEKAKRAL----ESQLAELKAQNEELED------DLQLTEDAKLRLE 1649
Query: 1219 TNVGPLSVFCEKEKLSIRDVVD--RLHWIKRLESTIAKMANEKADMTAKV---------- 1266
N+ L E++ L+ + + R +K+L ++ E+ TA V
Sbjct: 1650 VNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLEGDL 1709
Query: 1267 KDLETALS-QSKEKVDRYEEYSSKSQKVDKPRPNGEDPVALKETIVRLLKERKKLTAILK 1325
K++ET + +K K D + +V + E+ A KE + L KE ++ L+
Sbjct: 1710 KEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEAERKVKALE 1769
>Hs11321579 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 65.5 bits (158), Expect = 6e-10
Identities = 135/750 (18%), Positives = 292/750 (38%), Gaps = 91/750 (12%)
Query: 649 LELESPSNNFISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSE-GSKKPLIERQIE 707
L+++S + N + A R E L K ++ +K K T + E S+ +R +E
Sbjct: 893 LQVQSETENLMD----AEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLE 948
Query: 708 DGNVSEKTPQEPT----TSIPGETDVNE-KVLEPIEDIEMLPTFISSSNRLEPDANTLSA 762
D S K + T + E E KV E++ L IS + +
Sbjct: 949 DKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQ 1008
Query: 763 HALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETN-EGNSKKGKDELHFDP 821
L + K L +N A E Q D+ + S E E + ++ K +L D
Sbjct: 1009 QTLDDLQVEEDKVNGLIKIN---AKLEQ--QTDDLEGSLEQEKKLRADLERAKRKLEGDL 1063
Query: 822 EKC-EDVTQFRKEYLALRASISKDDTCSSSL---VNEDLNKTEVIQNLTSEIIQSEMKIA 877
+ E + E + + K + S L ++++ + Q E+ ++
Sbjct: 1064 KMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELE 1123
Query: 878 SLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSA----GTAKEAEVN--NKDKT 931
+ H LR K+E+ A+ ++E+ L E+ G+ SA +EAE +D
Sbjct: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183
Query: 932 ESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIK 991
E+ +A +L ++++ + + ++ + + + + E+K D N +
Sbjct: 1184 EATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALS 1243
Query: 992 QLRDTLEGERAHFESQLALEKQK----------VSNLKAALLSRHG--------KNDINE 1033
+ + +E E Q + K K ++ KA L +++G K +
Sbjct: 1244 KSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLIS 1303
Query: 1034 EVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNS 1093
++ + ++LEEL+ ++ A +A + + +C R E++ EL
Sbjct: 1304 QLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQR 1363
Query: 1094 KVALASKQCAQLRST-NAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGS 1152
++ A+ + AQ ++ + + LE+ K++ + + T+ + S +
Sbjct: 1364 ALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEA-------EEKTETANSKCA 1416
Query: 1153 EVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIK 1212
++++ ++ + L +S+ A +D+ + +L + +KL+ + +L+ K
Sbjct: 1417 SLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQK 1476
Query: 1213 TLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKR------------------------- 1247
L T + K + + +VVD+L ++R
Sbjct: 1477 ESRSLSTEL-------FKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQE 1529
Query: 1248 LESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYE-EYSSKSQKVDKPRPNGEDPVAL 1306
E T + EK+D+ ++++E +L + K+ R + E S ++D+ +
Sbjct: 1530 AEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDR------KVIEK 1583
Query: 1307 KETIVRLLKERKKLTAILKNQAESKERDPN 1336
E I +L + ++ L++ +++ R N
Sbjct: 1584 DEEIEQLKRNSQRAAEALQSVLDAEIRSRN 1613
Score = 57.0 bits (136), Expect = 2e-07
Identities = 120/659 (18%), Positives = 268/659 (40%), Gaps = 94/659 (14%)
Query: 705 QIEDGNVSEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNRLEPDANTLSAHA 764
Q ++G +S + +E + I T + + + +E+++ E A AHA
Sbjct: 1285 QTQNGELSHRV-EEKESLISQLTKSKQALTQQLEELKR-------QMEEETKAKNAMAHA 1336
Query: 765 LPSS---------------VIGVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETNEGN 809
L SS + Q +L+ N A ++ + D Q + E+E +
Sbjct: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKK 1396
Query: 810 SKKGKDELHFDPE----KCEDVTQFRK----EYLALRASISKDDTCSSSLVNEDLNKTEV 861
+ E E KC + + ++ E L + + T ++L + N +V
Sbjct: 1397 LAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKV 1456
Query: 862 IQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKG-------- 913
+ ++ +S+ ++ + + L +L ++ ++V +L+T+ E+K
Sbjct: 1457 LAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDL 1516
Query: 914 ----SFSAGTAKEAEVNNK----DKTE----------SINNEQAR----EKSLTAAHGKL 951
+ + +EAE K +K++ S+ +E+++ + L+ +L
Sbjct: 1517 TEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL 1576
Query: 952 ISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALE 1011
KV + EIE L +N ++ + D E+ + +L+ +EG+ E QL
Sbjct: 1577 DRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHS 1636
Query: 1012 KQKVSNLKAALLSRHGK-NDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHL 1070
++++ + L + G+ D + A + E+L+ +L+ + N L
Sbjct: 1637 NRQMAETQRHLRTVQGQLKDSQLHLDDAL----RSNEDLKEQLAIVE-----RRNGL--L 1685
Query: 1071 QTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNT 1130
E + L + + ++ AS + L S N L N + LE +++ +
Sbjct: 1686 LEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEV 1745
Query: 1131 KSKLKPSSYDSQNTQRSISGGS----EVQQSSLTPAQYEQNAPKKLPKSNGAITY-IDEN 1185
++ ++ S + +++I+ + E+++ T A E+ K L ++ + + +DE
Sbjct: 1746 ENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER-MKKNLEQTVKDLQHRLDEA 1804
Query: 1186 EILTKDILNDEVRKLNMTVLDLQRR-----------IKTLTKLETNVGPLSVFCEKEK-- 1232
E L +++KL V +L+ +K K E V ++ E+++
Sbjct: 1805 EQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDRKN 1864
Query: 1233 -LSIRDVVDRLHWIKRLESTIAKMANEKAD-MTAKVKDLETALSQSKEKVDRYEEYSSK 1289
L ++D+VD+L + A+ A E+A+ ++ + ++ L ++ E+ D E +K
Sbjct: 1865 ILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNK 1923
>SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1957
Score = 65.1 bits (157), Expect = 7e-10
Identities = 238/1228 (19%), Positives = 442/1228 (35%), Gaps = 166/1228 (13%)
Query: 245 RARASSGGTPTSKGSAAVPAAPKTKNKTDSQVSKIANEIQNSNKSRISKANSPIQRTTTT 304
RA +S + SA + + N Q+ K ++ S +S + I
Sbjct: 468 RACLNSSSNELKEKSALIDKKDQELNNLREQI-KEQKKVSESTQSSLQSLQRDILNEKKK 526
Query: 305 TSNIPSEAKELYNMLSSRLKRRNVLFDKKGTINSENNDKTGASVKVESSHVEI---IGSK 361
S+ EL L + + L + T+ +E + ++ S + +
Sbjct: 527 HEVYESQLNELKGELQTEISNSEHLSSQLSTLAAEKEAAVATNNELSESKNSLQTLCNAF 586
Query: 362 RDHTHTSFMELPSMQATIADLAKTTSLVKENSAQIEVDRNLIGPERSRKNEKEFQDLETR 421
++ S M+L + + L + + E+ ++E + I + + K Q R
Sbjct: 587 QEKLAKSVMQLKENEQNFSSLDTSFKKLNESHQELENNHQTITKQLKDTSSKLQQLQLER 646
Query: 422 TSSPAKESLASPSADTPERKVPQLDLTSPSFDSTPGVTEKMDLKEVPSPEYPSSAGQAVQ 481
+ KES S + K+ +L+ ++ S + ++ E + +A++
Sbjct: 647 ANFEQKESTLSDENNDLRTKLLKLEESNKSLIKKQEDVDSLEKNIQTLKEDLRKSEEALR 706
Query: 482 QS--ESSQISHVIQQAEGADSGSHHGIQVESSELNIPTIFEKKDNPQAASASGTFHHVDE 539
S E+ + VI +G H ++ + ++L+ K N +S +
Sbjct: 707 FSKLEAKNLREVIDNLKG----KHETLEAQRNDLHSSLSDAKNTNAILSS--------EL 754
Query: 540 KQSTEETAKLLA-LXXXXXXXXXXXXXXXHYVGDFQLLNTMKARMVGPKVAKWKAFN--- 595
+S+E+ +L A + V +Q ++ + + V N
Sbjct: 755 TKSSEDVKRLTANVETLTQDSKAMKQSFTSLVNSYQSISNLYHELRDDHVNMQSQNNTLL 814
Query: 596 --KSKFKDLMKYLIAE------------HTPLAARSDVS--------CSNDICNIRNYES 633
+SK K + L + H + S VS S D+ N+R+ +
Sbjct: 815 ESESKLKTDCENLTQQNMTLIDNVQKLMHKHVNQESKVSELKEVNGKLSLDLKNLRSSLN 874
Query: 634 VEVH-------HLQKLPPRLRYLELESPSNNFISKPLRANNRVEKLRKDELY-NGSKQKR 685
V + L +L LE ES N K L A ++ +EL+ K
Sbjct: 875 VAISDNDQILTQLAELSKNYDSLEQESAQLNSGLKSLEAEKQLLHTENEELHIRLDKLTG 934
Query: 686 RTRGSAPDSEGSKKPLIERQIEDGNVSEK--TPQEPTTSIPGETDVNEKVLEPIE-DIEM 742
+ + S K L RQ E N+ E+ + + TS+ + D +E DIE
Sbjct: 935 KLKIEESKSSDLGKKLTARQEEISNLKEENMSQSQAITSVKSKLDETLSKSSKLEADIEH 994
Query: 743 LPTFIS-----------SSNRLEPDANTLSAHALPSSVIGVKK-------QPSLTTVNK- 783
L +S S+ RL D + KK Q L+ V+
Sbjct: 995 LKNKVSEVEVERNALLASNERLMDDLKNNGENIASLQTEIEKKRAENDDLQSKLSVVSSE 1054
Query: 784 -----FPASFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPEKC--------EDVTQF 830
+S N D IE N KD+ + + E+ E+ Q
Sbjct: 1055 YENLLLISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKLGEENAQI 1114
Query: 831 RKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSE-------IIQSEMKIASLVGIN 883
+ E LALR K ++ V++ K++ ++ LT+E + QS +LV
Sbjct: 1115 KDELLALRKKSKKQHDLCANFVDDLKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEER 1174
Query: 884 HQLREKLEELEK-----------IQAKLVQ---ELDTVLLESKGSFSAGTAKEAEVNNKD 929
L +L +++K I++ LV+ ELDT L + K S S ++ + + D
Sbjct: 1175 SDLANRLSDMKKSLSDSDNVISVIRSDLVRVNDELDT-LKKDKDSLSTQYSEVCQ-DRDD 1232
Query: 930 KTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNV---TERLFEIKRIKDREVEN 986
+S+ + + +L +K E D+ E L+ N E+ R+ +EN
Sbjct: 1233 LLDSLKGCEESFNKYAVSLRELCTKSEIDVPVSEILDDNFVFNAGNFSELSRLTVLSLEN 1292
Query: 987 HPII--------KQLRDTLEGERAHFESQLA-LEKQ---------KVSNLKAALLSRHGK 1028
+ +L + L A F +A LEK + +L+ AL K
Sbjct: 1293 YLDAFNQVNFKKMELDNRLTTTDAEFTKVVADLEKLQHEHDDWLIQRGDLEKALKDSE-K 1351
Query: 1029 NDINEEVKPAAPLDG---------KKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRN 1079
N + +E + + K++ EL + L +L N HL E +
Sbjct: 1352 NFLRKEAEMTENIHSLEEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHLNQEIRLKED 1411
Query: 1080 LLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISS-------NTKS 1132
+L EK+ L ++ Q S+ +N+L+ + D S+ +S + S
Sbjct: 1412 VLKEKESLIISLEESLS----NQRQKESSLLDAKNELEHMLDDTSRKNSSLMEKIESINS 1467
Query: 1133 KLKPSSYDSQNTQRSISGGSEVQQSSLTPAQ----YEQNAPKKLPKSNGAITYIDENEIL 1188
L S++ + + ++ SL+ + Q A +K+ I +D
Sbjct: 1468 SLDDKSFELASAVEKLGALQKLHSESLSLMENIKSQLQEAKEKIQVDESTIQELDHEITA 1527
Query: 1189 TKDILNDEVRKLNMTVLDLQRRIKTLTKL----ETNVGPLSVFCEKEKLSIRDVVDRLHW 1244
+K+ ++ + + DL I+ L L ++ V LS E E L + L +
Sbjct: 1528 SKNNYEGKLNDKDSIIRDLSENIEQLNNLLAEEKSAVKRLSTEKESEILQFNSRLADLEY 1587
Query: 1245 IK-RLESTIAKMANEKADMTAKVKDLET-ALSQSKEKVDRYEEYSSKSQKVDKPRPNGED 1302
K ++ES + + + A T +++ E LS + +D + S D +
Sbjct: 1588 HKSQVESELGRSKLKLASTTEELQLAENERLSLTTRMLDLQNQVKDLSNIKDSLSEDLRT 1647
Query: 1303 PVALKETIVRLLKERKKLTAILKNQAES 1330
+L++++ L KE K I N ES
Sbjct: 1648 LRSLEDSVASLQKECK----IKSNTVES 1671
Score = 58.9 bits (141), Expect = 5e-08
Identities = 118/536 (22%), Positives = 222/536 (41%), Gaps = 84/536 (15%)
Query: 797 AQASTEIETNEGNSKKGKDEL-HFDPE--KCEDVTQFRKEYL-ALRASISKDDTCSSSLV 852
A+ S+ +E N+ + K K++L H + E EDV + ++ + +L S+S SSL+
Sbjct: 1379 AELSSRLEDNQLATNKLKNQLDHLNQEIRLKEDVLKEKESLIISLEESLSNQRQKESSLL 1438
Query: 853 N--------------EDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQA 898
+ ++ + E I+++ S + ++AS V EKL L+K+ +
Sbjct: 1439 DAKNELEHMLDDTSRKNSSLMEKIESINSSLDDKSFELASAV-------EKLGALQKLHS 1491
Query: 899 K---LVQELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISK- 954
+ L++ + + L E+K + E+++ + T S NN + GKL K
Sbjct: 1492 ESLSLMENIKSQLQEAKEKIQVDESTIQELDH-EITASKNNYE----------GKLNDKD 1540
Query: 955 -VEKDLVE-IEALNKNVTERLFEIKRIK-DREVENHPIIKQLRDTLEGERAHFESQLALE 1011
+ +DL E IE LN + E +KR+ ++E E +L D LE ++ ES+L
Sbjct: 1541 SIIRDLSENIEQLNNLLAEEKSAVKRLSTEKESEILQFNSRLAD-LEYHKSQVESELGRS 1599
Query: 1012 KQKVSNLKAALLSRHGKN--------DINEEVKPAAPLDGKKLEELQAELSSTRLYARAQ 1063
K K+++ L + D+ +VK + + E+L+ R+
Sbjct: 1600 KLKLASTTEELQLAENERLSLTTRMLDLQNQVKDLSNIKDSLSEDLRT--------LRSL 1651
Query: 1064 HNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVV 1123
++ LQ EC K + L + + A+L + +K++ +D
Sbjct: 1652 EDSVASLQKECKI-------KSNTVESLQDVLTSVQARNAELEDEVSRSVDKIRRRDDRC 1704
Query: 1124 SKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYID 1183
+S K KL + T +Q +T + + KK K +
Sbjct: 1705 EHLSGKLK-KLHSQLEEQHETF------FRAEQQRMTQLGFLKETVKKQEKLLKKLNLRQ 1757
Query: 1184 ENEILTKDILNDE--VRKLNMTVLDLQRRIKTLT-KLETNVGPLSVFCEKEKLSIRDVVD 1240
E I IL E +R + ++ LQ R+ + + G F + ++ + +V+D
Sbjct: 1758 EQLIPRSSILVYESYIRDIEKEIIVLQERLNGIELSQQLPKGYFGYFFKTNRVEM-EVLD 1816
Query: 1241 RLHWIKRLESTIAKMANEKADMTAKVK-DLETALSQSKEKVDRYEEYSSKSQKVDK 1295
K+ + + +A A+ K K DLE ++ KEK ++ YS K + + K
Sbjct: 1817 SF---KQQVAKLQFLAG--AEFIVKFKEDLEKCAAEEKEKQATFDNYSEKVENLGK 1867
Score = 57.8 bits (138), Expect = 1e-07
Identities = 108/575 (18%), Positives = 234/575 (39%), Gaps = 61/575 (10%)
Query: 792 LQPDNAQASTEIETNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSL 851
L+ +N S ++ ++ K E EDV+ F+K+ + ++ S + + L
Sbjct: 149 LEHENGILSLQLSSSNKKDKNTSSVTTLTSE--EDVSYFQKKLTNMESNFSAKQSEAYDL 206
Query: 852 VNEDLNKTEVI-------QNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQEL 904
+ L TE + + + ++ + +A N LR + E LEK+ LV
Sbjct: 207 SRQLLTVTEKLDKKEKDYEKIKEDVSSIKASLAEEQASNKSLRGEQERLEKL---LVSSN 263
Query: 905 DTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEA 964
TV T ++ E + + + +++ E+ + ++ KL+ +++ ++
Sbjct: 264 KTV----------STLRQTENSLRAECKTLQ-EKLEKCAINEEDSKLLEELKHNVANYSD 312
Query: 965 LNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLS 1024
+ ++L E + E +N +K RDTL + E L + + +LK + S
Sbjct: 313 AIVH-KDKLIEDLSTRISEFDN---LKSERDTLSIKNEKLEKLL---RNTIGSLKDSRTS 365
Query: 1025 RHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEK 1084
+ E+K + +L + +++LSS ++ + Q S+ ++ +
Sbjct: 366 NSQLEEEMVELKESNRTIHSQLTDAESKLSSFEQENKSLKGSIDEYQNNLSSKDKMVKQV 425
Query: 1085 KHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKI-----SSNTKSKLKPSSY 1139
+ E S +A A+ + A++ S K++ E + + SS+ + K K +
Sbjct: 426 SSQLEEARSSLAHATGKLAEINSERDFQNKKIKDFEKIEQDLRACLNSSSNELKEKSALI 485
Query: 1140 DSQ-----NTQRSISGGSEVQQSSLTPAQYEQ----NAPKKLPKSNGAITYIDENEILTK 1190
D + N + I +V +S+ + Q Q N KK + + + E+ T
Sbjct: 486 DKKDQELNNLREQIKEQKKVSESTQSSLQSLQRDILNEKKKHEVYESQLNEL-KGELQT- 543
Query: 1191 DILNDEVRKLNMTVLDLQRR--IKTLTKLETNVGPLSVFC----EKEKLSIRDVVDRLHW 1244
+I N E ++ L ++ + T +L + L C EK S+ + +
Sbjct: 544 EISNSEHLSSQLSTLAAEKEAAVATNNELSESKNSLQTLCNAFQEKLAKSVMQLKENEQN 603
Query: 1245 IKRLESTIAK-------MANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPR 1297
L+++ K + N +T ++KD + L Q + + +E+ +S D+
Sbjct: 604 FSSLDTSFKKLNESHQELENNHQTITKQLKDTSSKLQQLQLERANFEQ--KESTLSDENN 661
Query: 1298 PNGEDPVALKETIVRLLKERKKLTAILKNQAESKE 1332
+ L+E+ L+K+++ + ++ KN KE
Sbjct: 662 DLRTKLLKLEESNKSLIKKQEDVDSLEKNIQTLKE 696
Score = 54.7 bits (130), Expect = 1e-06
Identities = 196/1163 (16%), Positives = 435/1163 (36%), Gaps = 157/1163 (13%)
Query: 248 ASSGGTPTSKGSAAVPAAPKTKNKTDSQVSKIANEIQNSNKSRISKANSPIQ--RTTTTT 305
A G + S S+A+P P++ + + R +SPI + T
Sbjct: 85 AKLGSSEGSTASSALPLTPRSPSNASWLLV------------RGGLLDSPILDINSVTQK 132
Query: 306 SNIPSEAKELYNMLSSRLKRRNVLFDKKGTINSENNDKTGASVKVESSHVEIIGSKRDHT 365
SN+ +E K++ + L++ +L + + N ++ + + + V K +
Sbjct: 133 SNLLNELKQVRSKLAALEHENGILSLQLSSSNKKDKNTSSVTTLTSEEDVSYFQKKLTNM 192
Query: 366 HTSFMELPSMQATIADLAKTTSLVKENSAQIEVDRNLIGPERSRKNEKEFQDLETRTSSP 425
++F + Q+ DL++ V E + E D EK +D+ + +S
Sbjct: 193 ESNFS---AKQSEAYDLSRQLLTVTEKLDKKEKDY-----------EKIKEDVSSIKASL 238
Query: 426 AKESLASPSADTPERKVPQLDLTSPSFDSTPGVTEKM----------DLKEVPSPEYPSS 475
A+E ++ S + ++ +L ++S ST TE L++ E S
Sbjct: 239 AEEQASNKSLRGEQERLEKLLVSSNKTVSTLRQTENSLRAECKTLQEKLEKCAINEEDSK 298
Query: 476 AGQAVQQSESSQISHVIQQAEGADSGSHHGIQVESSELNIPTIFEKKDNPQAASASGTFH 535
+ ++ + ++ ++ + + + S + ++ + T+ K + + +
Sbjct: 299 LLEELKHNVANYSDAIVHKDKLIEDLSTRISEFDNLKSERDTLSIKNEKLEKLLRNTIGS 358
Query: 536 HVDEKQSTEETAK-LLALXXXXXXXXXXXXXXXHYVGDFQLLNTMKARMVGPKVAKWKAF 594
D + S + + ++ L + F+ N + + + +++
Sbjct: 359 LKDSRTSNSQLEEEMVELKESNRTIHSQLTDAESKLSSFEQEN----KSLKGSIDEYQ-- 412
Query: 595 NKSKFKDLMKYLIAEHTPLAARSDVSCSNDICNI---RNYESVEVHHLQKLPPRLRYLEL 651
N KD M ++ A S + + I R++++ ++ +K+ LR L
Sbjct: 413 NNLSSKDKMVKQVSSQLEEARSSLAHATGKLAEINSERDFQNKKIKDFEKIEQDLRAC-L 471
Query: 652 ESPSNNFISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIERQIEDGNV 711
S SN K + +KD+ N +++ + + +S S ++R I +
Sbjct: 472 NSSSNELKEKSALID------KKDQELNNLREQIKEQKKVSESTQSSLQSLQRDILNEKK 525
Query: 712 SEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTF-------ISSSNRLEPDANTLSA-- 762
+ + + GE E + L T ++++N L N+L
Sbjct: 526 KHEVYESQLNELKGELQTEISNSEHLSS--QLSTLAAEKEAAVATNNELSESKNSLQTLC 583
Query: 763 ----HALPSSVIGVKKQP--------SLTTVNKFPASFENGLQP------DNAQASTEIE 804
L SV+ +K+ S +N+ EN Q D + +++
Sbjct: 584 NAFQEKLAKSVMQLKENEQNFSSLDTSFKKLNESHQELENNHQTITKQLKDTSSKLQQLQ 643
Query: 805 TNEGNSKKGKDELHFDP------------------EKCEDVTQFRKEYLALRASISKDDT 846
N ++ + L + +K EDV K L+ + K +
Sbjct: 644 LERANFEQKESTLSDENNDLRTKLLKLEESNKSLIKKQEDVDSLEKNIQTLKEDLRKSEE 703
Query: 847 CSSSLVNEDLNKTEVIQNL-----TSEIIQSEM--KIASLVGINHQLREKLEELEKIQAK 899
E N EVI NL T E ++++ ++ N L +L + + +
Sbjct: 704 ALRFSKLEAKNLREVIDNLKGKHETLEAQRNDLHSSLSDAKNTNAILSSELTKSSEDVKR 763
Query: 900 LVQELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREK-SLTAAHGKLISKVEKD 958
L ++T+ +SK + T+ VN+ ++ +E + ++ + + L+ K
Sbjct: 764 LTANVETLTQDSKAMKQSFTSL---VNSYQSISNLYHELRDDHVNMQSQNNTLLESESKL 820
Query: 959 LVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNL 1018
+ E L + + ++++ + V + +L++ +L+L+ + NL
Sbjct: 821 KTDCENLTQQNMTLIDNVQKLMHKHVNQESKVSELKEV--------NGKLSLD---LKNL 869
Query: 1019 KAALLSRHGKND--INEEVKPAAPLDGKKLEELQAELSSTRLYARAQ--HNAAKHLQTEC 1074
+++L ND + + + + D + E Q L A Q H + L
Sbjct: 870 RSSLNVAISDNDQILTQLAELSKNYDSLEQESAQLNSGLKSLEAEKQLLHTENEELHIRL 929
Query: 1075 STYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKL 1134
L ++ K ++L K+ ++ + L+ N ++ Q++ V SK+ T SK
Sbjct: 930 DKLTGKLKIEESKSSDLGKKLTARQEEISNLKEEN---MSQSQAITSVKSKL-DETLSKS 985
Query: 1135 KPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILN 1194
D ++ + +S EV++++L + + L K+NG + EI K N
Sbjct: 986 SKLEADIEHLKNKVS-EVEVERNALLAS--NERLMDDL-KNNGENIASLQTEIEKKRAEN 1041
Query: 1195 DEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAK 1254
D+++ ++V+ + L +TN + + D+ + +K +E + K
Sbjct: 1042 DDLQS-KLSVVSSEYENLLLISSQTN---------------KSLEDKTNQLKYIEKNVQK 1085
Query: 1255 MANEKADMTAKVKDLETALSQSKEK----VDRYEEYSSKSQKVDKPRPNGEDPVALK-ET 1309
+ +EK ++++L + + E+ D KS+K N D + K +
Sbjct: 1086 LLDEKDQRNVELEELTSKYGKLGEENAQIKDELLALRKKSKKQHDLCANFVDDLKEKSDA 1145
Query: 1310 IVRLLKERKKLTAILKNQAESKE 1332
+ +L E+ +L L+ + E
Sbjct: 1146 LEQLTNEKNELIVSLEQSNSNNE 1168
Score = 53.5 bits (127), Expect = 2e-06
Identities = 101/466 (21%), Positives = 183/466 (38%), Gaps = 70/466 (15%)
Query: 855 DLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGS 914
D+N NL +E+ Q K+A+L N L +L K + K + T+ E S
Sbjct: 125 DINSVTQKSNLLNELKQVRSKLAALEHENGILSLQLSSSNK-KDKNTSSVTTLTSEEDVS 183
Query: 915 FSAGTAKEAEVNNKDKTESINNEQAREKS---LTAAHGKLISKVEKDLVEIEALNKNVTE 971
+ + ++ N + S +A + S LT + + K EKD +I+
Sbjct: 184 YF-----QKKLTNMESNFSAKQSEAYDLSRQLLTVT--EKLDKKEKDYEKIKE------- 229
Query: 972 RLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDI 1031
++ IK E K LR GE Q LEK VS+ K R +N +
Sbjct: 230 ---DVSSIKASLAEEQASNKSLR----GE------QERLEKLLVSSNKTVSTLRQTENSL 276
Query: 1032 NEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKH-------------LQTECSTYR 1078
E K +KLE+ ++L +HN A + L T S +
Sbjct: 277 RAECKTLQ----EKLEKCAINEEDSKLLEELKHNVANYSDAIVHKDKLIEDLSTRISEFD 332
Query: 1079 NLLSEK---KHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSN-TKSKL 1134
NL SE+ K +L + R++N+ L ++ L++ I S T ++
Sbjct: 333 NLKSERDTLSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMVELKESNRTIHSQLTDAES 392
Query: 1135 KPSSYDSQNTQRSISGGSEVQQSSLTP--------AQYEQNAPKKLPKSNGAITYIDENE 1186
K SS++ +N +S+ G + Q++L+ + + A L + G + I+
Sbjct: 393 KLSSFEQEN--KSLKGSIDEYQNNLSSKDKMVKQVSSQLEEARSSLAHATGKLAEINSE- 449
Query: 1187 ILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIK 1246
+D N +++ DL+ L + S +K+ + ++ +++ K
Sbjct: 450 ---RDFQNKKIKDFEKIEQDLR---ACLNSSSNELKEKSALIDKKDQELNNLREQIKEQK 503
Query: 1247 RL-ESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQ 1291
++ EST + + + + D+ + K E SQ E + S S+
Sbjct: 504 KVSESTQSSLQSLQRDILNEKKKHEVYESQLNELKGELQTEISNSE 549
>Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2349
Score = 65.1 bits (157), Expect = 7e-10
Identities = 163/817 (19%), Positives = 323/817 (38%), Gaps = 142/817 (17%)
Query: 617 SDVSCSNDICN-----IRNYESVEVHHLQKLPPRLRYL-------ELESPSNNFISKPLR 664
+D+S S+++ + RN E ++ + Q+L LR L E E+ S+ L+
Sbjct: 524 ADISSSSEVISQHLVSYRNIEELQQQN-QRLLVALRELGETREREEQETTSSKITELQLK 582
Query: 665 ---ANNRVEKLRKDELYNGS------KQKRRTRGSAPDSEGSKKPLIERQIEDGNVSEKT 715
A +E+LRK + +Q+ R + G PL ++D +++ T
Sbjct: 583 LESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLAS-T 641
Query: 716 PQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNRLEPDANTLSAHALPSSVIGVKKQ 775
P+ P+TS T V+E E IE E + + + K Q
Sbjct: 642 PKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQ 701
Query: 776 PSLTTVNKFPASFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPEKCEDVTQFRKEYL 835
+T L+ N + ST+++ + +D +V +R+E
Sbjct: 702 EQVTD-----------LRSQNTKISTQLDFASKRYEMLQD----------NVEGYRREIT 740
Query: 836 ALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEK 895
+L K L + ++I +T ++ + K+A L+++ E L+
Sbjct: 741 SLHERNQK-------LTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKL 793
Query: 896 IQAKLVQELDTVLLESKGSFSAGTAKEA--EVNNKDKTESINNEQAREKSLTAAHGKLIS 953
+ +L Q+ +++L E +G T + + + +TE+ ++ + L L
Sbjct: 794 SEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKK 853
Query: 954 KVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQ 1013
K+E ++ + L +N+ +L + KR D E H K+L + E +A KQ
Sbjct: 854 KLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKE-------IATLKQ 906
Query: 1014 KVSNLKAALLS----RHGK---------NDINEEVKPAAPLDGKKLEELQAELSSTRLY- 1059
+SN++ + S R GK +D+ +++ E L+ S+ Y
Sbjct: 907 HLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQ 966
Query: 1060 ---ARAQHNAAKHLQTECSTYRNL---LSEKKHKYNELNSKVALASKQCAQL----RSTN 1109
+ + K Q +N+ L E +L K+ K+ +L R
Sbjct: 967 AMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAI 1026
Query: 1110 AHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSL-TPAQYE--- 1165
+ +L L+ +S + + + L+ +S N Q++ E + ++ +YE
Sbjct: 1027 ESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYEREL 1086
Query: 1166 ----------QNAPKKLPKSNGAITYID------ENEIL--------TKDILNDEVRKLN 1201
Q A +++ K +++ E+++L + +L DEV K
Sbjct: 1087 MLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCV 1146
Query: 1202 MTVLDLQRRIKTL----TKLETNV---------GPLSVFCEKEKLSIRDVVDRLHWIKRL 1248
DL+++ + L KL V GPL+V +E S +++ L +I+R
Sbjct: 1147 CRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRR- 1205
Query: 1249 ESTIAKMANEKADMTA------------KVKDLETALSQSKEKVDRYEEYSSKSQKVDKP 1296
E IA+ E A + + ++++LE +L+ +EKV + ++ +++ K
Sbjct: 1206 EKEIAETRFEVAQVESLRYRQRVELLERELQELEDSLNAEREKVQVTAKTMAQHEELMK- 1264
Query: 1297 RPNGEDPVALKETIVRLLKERKKLTAILKNQAESKER 1333
E + ET L +E+++L L+ Q ++K R
Sbjct: 1265 --KTETMNVVMETNKMLREEKERLEQDLQ-QMQAKVR 1298
Score = 62.4 bits (150), Expect = 5e-09
Identities = 91/451 (20%), Positives = 189/451 (41%), Gaps = 41/451 (9%)
Query: 838 RASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQ 897
R + KD+ EDL K + + E + ++ + G+ L L E K Q
Sbjct: 1134 RERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQ 1193
Query: 898 AKLVQELDTVLLESKGSFSAGTAKEAE-VNNKDKTESINNE-QAREKSLTAAHGKLISKV 955
++++ L + E + + + + E + + + E + E Q E SL A
Sbjct: 1194 EQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELEDSLNA--------- 1244
Query: 956 EKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKV 1015
E++ V++ A E L ++ E ++ + L E+ E L + KV
Sbjct: 1245 EREKVQVTAKTMAQHEELM-------KKTETMNVVMETNKMLREEKERLEQDLQQMQAKV 1297
Query: 1016 SNLKAALLSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECS 1075
L+ +L N E + K LEE R AR QH ++ +
Sbjct: 1298 RKLELDILPLQEANAELSEKSGMLQAEKKLLEE-----DVKRWKARNQHLVSQQKDPDTE 1352
Query: 1076 TYRNLLSEKK---HKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKS 1132
YR LLSEK+ + +L ++ + A+ ++ + +N +QSL++ ++K+ + ++
Sbjct: 1353 EYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKET 1412
Query: 1133 ---KLKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQ-NAPKKLPKSNGAITYIDENEIL 1188
L D Q ++I+ ++ + T QYE+ A + A + D E
Sbjct: 1413 IQKDLDAKIIDIQEKVKTITQVKKIGRRYKT--QYEELKAQQDKVMETSAQSSGDHQE-- 1468
Query: 1189 TKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRL 1248
+ + E+++L T+ + + K+ LE+ V L +++ R++ ++ +L
Sbjct: 1469 -QHVSVQEMQELKETLNQAETKSKS---LESQVENLQKTLSEKETEARNLQEQ---TVQL 1521
Query: 1249 ESTIAKMANEKADMTAKVKDLETALSQSKEK 1279
+S ++++ + D T + + L +++ +EK
Sbjct: 1522 QSELSRLRQDLQDRTTQEEQLRQQITEKEEK 1552
Score = 53.9 bits (128), Expect = 2e-06
Identities = 123/602 (20%), Positives = 246/602 (40%), Gaps = 92/602 (15%)
Query: 779 TTVNKFPASFENGLQPDNAQASTEIETNEGNSKKGK---DELHFDPEKCEDVTQFR---- 831
T +NK P S +N L+ A +EI+ +G +K K ++ +F+ EK +Q R
Sbjct: 12 TELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNE 71
Query: 832 -KEYLALRASISKDDTCSSSLVNEDLNKTEVIQN----------LTSEIIQSEMKIASLV 880
+E +LR + K + +L ++ + E+ Q+ T E +++E + L+
Sbjct: 72 TRECQSLRLELEKLNNQLKALTEKN-KELEIAQDRNIAIQSQFTRTKEELEAEKR--DLI 128
Query: 881 GINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAR 940
N +L ++LE L + +L ++L KE+ + ++ QA
Sbjct: 129 RTNERLSQELEYLTEDVKRLNEKL----------------KESNTTKGELQLKLDELQAS 172
Query: 941 EKSLTAAHGKLISKVEKDLVEIEA--LN---KNVTERLFEIKRIKDREVENHPIIKQLRD 995
+ S+ +L + EK+L+ + LN K T+ L + R K E I +L+
Sbjct: 173 DVSVKYREKRL--EQEKELLHSQNTWLNTELKTKTDELLALGREKGNE------ILELKC 224
Query: 996 TLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGKKLEELQAELSS 1055
LE +K++VS L+ + +G NE ++ KL+E + + +S
Sbjct: 225 NLEN-----------KKEEVSRLEEQM---NGLKTSNEHLQKHVEDLLTKLKEAKEQQAS 270
Query: 1056 TRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNK 1115
+ NA H++ + Y++ + + K NEL V K + N +++
Sbjct: 271 MEEKFHNELNA--HIKLS-NLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDH 327
Query: 1116 LQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISG----GSEVQQSSLTPAQYEQNAPKK 1171
L +E ++ K+ + +N +S G+ + + L A K
Sbjct: 328 LLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAK 387
Query: 1172 LPKSNGAITYIDENEILTKD--------------ILNDEVRKLNMTVLDLQRRIKTLTKL 1217
+ K +T + + T+D L++ V+++ L+R+ + +
Sbjct: 388 IVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERA 447
Query: 1218 ETNVGPLSVFCE---KEKLSIRDVVDRLH-WIKRLESTIAKMANEKADMTAKVKDLETAL 1273
+ V LSV E KE +++ D+ + LE +M + D++ +++ L L
Sbjct: 448 QKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMEL 507
Query: 1274 SQSK-EKVDRYEEYSSKSQKVDKPRPNGEDPVALKETIVRLLKERKKLTAILKNQAESKE 1332
+++ V R EE SS + + I L ++ ++L L+ E++E
Sbjct: 508 EEARGNHVIRDEEVSSAD--ISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETRE 565
Query: 1333 RD 1334
R+
Sbjct: 566 RE 567
>Hs11342672 [Z] KOG0161 Myosin class II heavy chain
Length = 1940
Score = 64.3 bits (155), Expect = 1e-09
Identities = 155/736 (21%), Positives = 292/736 (39%), Gaps = 109/736 (14%)
Query: 658 FISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIER------------- 704
F KPL + EK E+ ++ ++T+ SE +K L E+
Sbjct: 835 FKIKPLLKSAETEK----EMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQL 890
Query: 705 --QIEDGNV---SEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNR-LEPDAN 758
Q E N+ E+ Q E + E V E ED E + +++ R LE + +
Sbjct: 891 QVQAESENLLDAEERCDQLIKAKFQLEAKIKE-VTERAEDEEEINAELTAKKRKLEDECS 949
Query: 759 TLSAHA--LPSSVIGVKKQPSLTTVNKFPASFE--NGLQPDNAQASTEIETNEGNSKKGK 814
L L ++ V+K+ T NK E +GL A+ + E + + ++
Sbjct: 950 ELKKDIDDLELTLAKVEKEKHATE-NKVKNLTEELSGLDETIAKLTREKKALQEAHQQAL 1008
Query: 815 DELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQN---LTSEIIQ 871
D+L + +K V K L + + SSL E + ++ +N L ++
Sbjct: 1009 DDLQAEEDK---VNSLNKTKSKLEQQV---EDLESSLEQEKKLRVDLERNKRKLEGDLKL 1062
Query: 872 SEMKIASLVGINHQLREKLEELE----KIQAKLVQELDTVLLESKGSFSAGTAKEAEVNN 927
++ I L QL E+L++ + ++Q+K+ E L K KE +
Sbjct: 1063 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQK------KIKELQARI 1116
Query: 928 KDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVE-- 985
++ E I E+A +K EK + + ++ERL E + ++E
Sbjct: 1117 EELEEEIEAERATR-----------AKTEKQRSDYARELEELSERLEEAGGVTSTQIELN 1165
Query: 986 --NHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDG 1043
+LR LE E+ +A ++K ++ A L + D + VK
Sbjct: 1166 KKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQI---DNLQRVKQKLE--- 1219
Query: 1044 KKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCA 1103
K+ E + E+ + + +L+ C T + LSE + K E+ ++ + Q +
Sbjct: 1220 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 1279
Query: 1104 QLRSTNAHLRNKLQSLEDVVSKISSNTKS------KLKPSSYDSQNTQRSISGG--SEVQ 1155
+L++ L +L+ E +VS++S + ++ +LK + + +++ S
Sbjct: 1280 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 1339
Query: 1156 QSSLTPAQYEQNAPKK------LPKSNGAI----TYIDENEILTKDILNDEVRKLNMTVL 1205
L QYE+ K L K+N + T + + I + L + KL +
Sbjct: 1340 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQ 1399
Query: 1206 DLQRRI-----------KTLTKLETNVGPLSVFCEKEKLSIRDVVDR--LHWIKRLESTI 1252
D + ++ KT +L+ V L V E+ S+ +D+ ++ K L
Sbjct: 1400 DSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN-SLAAALDKKQRNFDKVLAEWK 1458
Query: 1253 AKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNGEDPVA-LKE--- 1308
K +A++ A +K+ + ++ + + YEE + + V + N E +A L E
Sbjct: 1459 TKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIA 1518
Query: 1309 ----TIVRLLKERKKL 1320
TI L K RK++
Sbjct: 1519 ENGKTIHELEKSRKQI 1534
Score = 60.8 bits (146), Expect = 1e-08
Identities = 107/506 (21%), Positives = 207/506 (40%), Gaps = 60/506 (11%)
Query: 814 KDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVN------EDLNKTEVIQNLTS 867
K + +FD E T+ + L AS+ + + S+ L E L++ E ++
Sbjct: 1445 KKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENK 1504
Query: 868 EIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNN 927
+ E +IA L + + + ELEK + ++ E + L +EAE
Sbjct: 1505 NL---EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQL---------ALEEAEA-- 1550
Query: 928 KDKTESINNEQAR----EKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDRE 983
++ +E+A+ + LT ++ K+ + EIE L +N + ++ D E
Sbjct: 1551 -----ALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAE 1605
Query: 984 VENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGK-NDINEEVKPAAPLD 1042
V + +L+ +EG+ E QL+ ++ + L S G+ D + A L
Sbjct: 1606 VRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDA--LR 1663
Query: 1043 GKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQC 1102
G+ E+L+ +L+ A + L+ + + + N +V L Q
Sbjct: 1664 GQ--EDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQN 1721
Query: 1103 AQLRSTNAHLRNKLQSLEDVV---SKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSL 1159
L T L L L+ V S+ + N + K K + D+ E+++
Sbjct: 1722 TSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMM------AEELKKEQD 1775
Query: 1160 TPAQYEQNAPKKLPKSNGAITY-IDENEILTKDILNDEVRKLNMTVLDLQ---------- 1208
T A E+ K L ++ + + +DE E L +++KL + +L+
Sbjct: 1776 TSAHLER-MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKN 1834
Query: 1209 -RRIKTLTKLETNVGPLSVFCEKEK---LSIRDVVDRLHWIKRLESTIAKMANEKADM-T 1263
+K L K E V L+ E+++ L ++D+VD+L + A+ A+E+A+
Sbjct: 1835 TESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHL 1894
Query: 1264 AKVKDLETALSQSKEKVDRYEEYSSK 1289
K + + L +++E+ D E +K
Sbjct: 1895 TKFRKAQHELEEAEERADIAESQVNK 1920
>CE26070 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 2083
Score = 64.3 bits (155), Expect = 1e-09
Identities = 144/751 (19%), Positives = 296/751 (39%), Gaps = 94/751 (12%)
Query: 632 ESVEVHHLQKLPPRLRYLELESPSNNFISKPLRANNRVEKLRKDELYNGSKQKRRTRGSA 691
ES E +++ ++ +PS+ K + + V + K + + +K+ G
Sbjct: 591 ESQETLNVEIAVTETTVQKITNPSDESAKKDVNEDTAVSSIVKKDDKDVNKKSLPESGLT 650
Query: 692 PDSEGSKKP---LIERQIE--DGNVSEKTP---QEPTTSIPGETDVNEKVLEP-IEDIEM 742
E KP +++++ E D ++SE + ++ T + E + ++ E ++D
Sbjct: 651 TKKEIQGKPEKKIMKKKTEKADSSISETSETLTKDLTQTKQSEPEPAKRTTETSVQDEVK 710
Query: 743 LPTFISSSNRLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQASTE 802
T +S ++ T H P G K S+++ + AS +Q ++A
Sbjct: 711 RKTETTSKSK-----QTTEEHPQP----GGKSDSSISSTSD--ASEVKQVQQSESEAQKV 759
Query: 803 IETNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVI 862
E E + K ++ D K D + E + + K T S + ++T +
Sbjct: 760 TEKPETAKLESKSKMTEDTTKESDNKETVDE--KPKKKVLKKKTEKSDSTISETSETSAV 817
Query: 863 QNLTSEIIQSEMKIASLVGINHQLREK-LEELEKIQAKLVQELDTVL---LESKGSFSAG 918
++ SE + ++ ++ + ++K +E +K++A++ + T LE++
Sbjct: 818 ESAGP----SESETQNVAAVDKEKKQKETDEKQKLEAEIAGKKSTEQKSKLEAEAKLKRA 873
Query: 919 TAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLV----EIEALNKNVTERLF 974
++A K+KTE+ + + A EK ++ E D V E++ NK +
Sbjct: 874 AEEDAAKKQKEKTEAASKKAAAEKLELEKQAQINKAAEADAVKKQNELDEQNKLEATKKL 933
Query: 975 EIKRIKDRE----VENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKND 1030
+++K E +Q + + + E Q LEK + SN + G N+
Sbjct: 934 AAEKLKLEEQSAAKSKQAAEEQAKLDAQTKAKAAEKQTGLEKDEKSNKDS------GSNE 987
Query: 1031 INEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNE 1090
EE KP + KK E+ + +S ++ +A ++E + S++K +
Sbjct: 988 TVEE-KPKKKVLKKKTEKSDSSISQKSDTSKTVAESAGSSESETQKVADATSKQKETDKK 1046
Query: 1091 LNSKVALASKQCAQLRS---TNAHL--------------RNKLQSLEDVVSKISSNTKSK 1133
+ + +K+ A +S T + L +KL+ DV SK ++ K +
Sbjct: 1047 QKLEAEITAKKSADEKSKLETESKLIKAAEDAAKKQKEKEDKLKLEADVASKKAAAEKLE 1106
Query: 1134 L-------KPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENE 1186
L K + D+ Q+ ++ +++ + T ++ A +KL ++E
Sbjct: 1107 LEKQAQIKKAAEADAVKKQKELAEKQKLESEAAT----KKAAAEKLK--------LEEQA 1154
Query: 1187 ILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIK 1246
+ K D V+K Q+ + KLE N + + E+ S +
Sbjct: 1155 QINKAAEADAVKK--------QKELDEKNKLEANKKSAAEKLKLEEESAAKSKQTVEEQA 1206
Query: 1247 RLESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNGEDPVAL 1306
+L++ + EK K D T S+SKE VD + +K +K +
Sbjct: 1207 KLDAQTKEKTAEKQTGLEK-DDKSTKDSESKETVDEKPKKKVLKKKTEKSDSSISQKSVT 1265
Query: 1307 KETIVR----LLKERKKLTAILKNQAESKER 1333
+T+V E +K+ + Q E+ E+
Sbjct: 1266 SKTVVESGGPSESETQKVADAARKQKETDEK 1296
Score = 63.9 bits (154), Expect = 2e-09
Identities = 202/1170 (17%), Positives = 430/1170 (36%), Gaps = 102/1170 (8%)
Query: 155 KVSSPPQSNIDKAPQRKPLERTGLSKRVVEDEVXXXXXXXXXXXGRIHKHIESPFQRNSK 214
K+++P D++ ++ E T +S V +D+ K I+ ++ K
Sbjct: 609 KITNPS----DESAKKDVNEDTAVSSIVKKDDKDVNKKSLPESGLTTKKEIQGKPEK--K 662
Query: 215 PVSKSIVKAPNKVNFAFETSLNDIDLNLLTRARASSGGTPTSKGSAAVPAAPKTKNKTDS 274
+ K KA + ++ ET D LT+ + S +V K K +T S
Sbjct: 663 IMKKKTEKADSSISETSETLTKD-----LTQTKQSEPEPAKRTTETSVQDEVKRKTETTS 717
Query: 275 QVSKIANEIQNSNKSRISKANSPIQRTTTTTSNIPSEAKELYNMLSSRLKRRNVLFDKKG 334
+ + E K++S I T S+A E+ + S + + V +K
Sbjct: 718 KSKQTTEEHPQPG----GKSDSSISST--------SDASEVKQVQQSESEAQKVT-EKPE 764
Query: 335 TINSENNDKTGASVKVESSHVEIIGSKRDHTHTSFMELPSMQATIADLAKTTSLVKENSA 394
T E+ K ES + E + K + +TI++ ++T+++ +
Sbjct: 765 TAKLESKSKMTEDTTKESDNKETVDEKPKKKVLK-KKTEKSDSTISETSETSAVESAGPS 823
Query: 395 QIEVDR-NLIGPERSRKNEKEFQDLETRTSSP-AKESLASPSADTPERKVPQLDLTSPSF 452
+ E + E+ +K E Q LE + + E + A+ ++ + D
Sbjct: 824 ESETQNVAAVDKEKKQKETDEKQKLEAEIAGKKSTEQKSKLEAEAKLKRAAEEDAAKKQK 883
Query: 453 DSTPGVTEKMDLKEVPSPEYPSSAGQAVQQSESSQISHVIQQAEGADSGSHHGIQVESSE 512
+ T ++K +A + ++ + +QI+ +A AD+ E ++
Sbjct: 884 EKTEAASKK-------------AAAEKLELEKQAQIN----KAAEADAVKKQNELDEQNK 926
Query: 513 LNIPTIF---EKKDNPQAASASGTFHHVDEKQSTEETAKLLALXXXXXXXXXXXXXXXHY 569
L + K Q+A+ S KQ+ EE AKL A
Sbjct: 927 LEATKKLAAEKLKLEEQSAAKS--------KQAAEEQAKLDAQTKAKAAEKQTGLEKDEK 978
Query: 570 VGDFQLLNTMKARMVGPKVAKWKAFNKSKFKDLMKYLIAEHTPLAARSDVSCSNDICNIR 629
N KV K K KS K ++ +A S S + + +
Sbjct: 979 SNKDSGSNETVEEKPKKKVLKKKT-EKSDSSISQKSDTSKTVAESAGSSESETQKVADAT 1037
Query: 630 NYESVEVHHLQKLPPRLRYLELESPSNNFISKPLRANNRVEKLRKDELYNGSKQKRRTRG 689
+ + E QKL E+ + + L +++ K +D KQK +
Sbjct: 1038 SKQK-ETDKKQKLEA-----EITAKKSADEKSKLETESKLIKAAEDA---AKKQKEKEDK 1088
Query: 690 SAPDSEGSKKPLIERQIEDGNVSEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISS 749
+++ + K ++E ++ ++ + ++ EK + +E +
Sbjct: 1089 LKLEADVASKKAAAEKLELEKQAQIKKAAEADAVKKQKELAEK--QKLESEAATKKAAAE 1146
Query: 750 SNRLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETNEGN 809
+LE A A + VKKQ L NK A+ ++ + + + ++ +
Sbjct: 1147 KLKLEEQAQINKA----AEADAVKKQKELDEKNKLEANKKSAAEKLKLEEESAAKSKQTV 1202
Query: 810 SKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEI 869
++ K + + E T K+ + + S SK+ KTE + S+
Sbjct: 1203 EEQAKLDAQTKEKTAEKQTGLEKDDKSTKDSESKETVDEKPKKKVLKKKTEKSDSSISQK 1262
Query: 870 IQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKD 929
+ + G + +K+ + + Q + + K A + + K
Sbjct: 1263 SVTSKTVVESGGPSESETQKVADAARKQKET---------DEKQKLEAEITAKKSADEKS 1313
Query: 930 KTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEI-KRIKDREVENHP 988
K E+ + ++ + A K K E+ ++ EA +K E+ K+ + ++
Sbjct: 1314 KLEA--ESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQAQIKKAAEAD 1371
Query: 989 IIKQLRDTLEGERAHFES--------QLALEKQKVSNLKAALLSRHGKNDINEEVKPAAP 1040
+K+ ++ E ++ E+ +L LE+QK + + A + + + + + +
Sbjct: 1372 AVKKEKELAEKQKLESEAATKKAAAEKLKLEEQKKKDAETASIEKQKEQEKLAQEQSKLE 1431
Query: 1041 LDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASK 1100
+D KK E Q S T+ ++ A K E + +L +K K + S+ + +K
Sbjct: 1432 VDAKKSAEKQKLESETK--SKKTEEAPKESVDE-KPKKKVLKKKTEKSDSSISQKSDTAK 1488
Query: 1101 QCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLT 1160
A+ + K+ + + S+ K KL+ ++ ++ +E + +
Sbjct: 1489 TVAESAGQSDSETQKVSEADKAHKQKESDEKQKLESEIAAKKSAEQKSKLETEAKTKKVI 1548
Query: 1161 PAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETN 1220
+ + ++ K G + + + K L E T + Q+ KT + +
Sbjct: 1549 EDESAKKQKEQEDKKKGDDSAKKQKDQKEKQKLESEATSKKPT-SEKQKDEKTPQEKAKS 1607
Query: 1221 VGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKV 1280
+ E ++L ++ + + +E +A + EK+D D +T + K+K+
Sbjct: 1608 ENETVMTTEPQQLEVKSEPKKSDKTETVEKEVAS-STEKSD------DSKTKEPKEKKKI 1660
Query: 1281 DRYEEYSSKSQKVDKPRPNGEDPVALKETI 1310
+ ++ ++K Q+ K + E + L+ I
Sbjct: 1661 IKKKKDTTKPQEASKELSSDESRIDLESDI 1690
>Hs4502443 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 2649
Score = 63.5 bits (153), Expect = 2e-09
Identities = 117/547 (21%), Positives = 224/547 (40%), Gaps = 61/547 (11%)
Query: 824 CEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGIN 883
C VT ++E+ +A K + N + ++ LT E+ +++ S
Sbjct: 1346 CRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQD--MRELTYELNALQLEKTSSEEKA 1403
Query: 884 HQLREKLEELEKIQAKLVQELDTVLLESKG------------SFSAGTAKEAEVNNKDKT 931
L++KL+E L EL+ KG + + G A+EA D
Sbjct: 1404 RLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLK 1463
Query: 932 ESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKD-REVENHPII 990
+ N Q +SL GKL +V++ KN+ +I +D +E+E I
Sbjct: 1464 KIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQIC 1523
Query: 991 KQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPA---APLDGKKLE 1047
++ D L+ + FE +Q + N+KA + +NEE++ + A + +K+E
Sbjct: 1524 QRKSDHLKEQ---FEKS---HEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVE 1577
Query: 1048 ELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRS 1107
EL + + T+L + +Q E N++ EK+ + A QLRS
Sbjct: 1578 ELTRQNNETKLMMQ-------RIQAESE---NIVLEKQTIQQRCEALKIQADGFKDQLRS 1627
Query: 1108 TNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQ--QSSLTPAQYE 1165
TN HL + ++ +D KI + K + S+ Q+ +Q + + E
Sbjct: 1628 TNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAE 1687
Query: 1166 QNAPKKLPKSNGAITYIDENEILTKDILNDEVRK----LNMTVLDLQRRIKTLTKLETNV 1221
NA K+ + + + ++ LN+ ++K L++ ++ Q + + +
Sbjct: 1688 LNASKEEKRRGEQKVQLQQAQV---QELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEES 1744
Query: 1222 GPLSVFCEK-----EKLSIRDVV--DRLHWIKRLESTIAKMANEKADMTAK-----VKDL 1269
G E+ EKL V+ + + I RL+ + N +A AK +K+L
Sbjct: 1745 GKFKQSAEEFRKKMEKLMESKVITENDISGI-RLDFVSLQQENSRAQENAKLCETNIKEL 1803
Query: 1270 ETALSQSKEKVDRYE----EYSSKSQKV-DKPRPNGEDPVALKETIVRLLKERKKLTAIL 1324
E L Q +E++ + + + K QK+ D+ + LK+ + + +KE + +L
Sbjct: 1804 ERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQLVLL 1863
Query: 1325 KNQAESK 1331
+ + + K
Sbjct: 1864 QCEIQKK 1870
>CE27133 [Z] KOG0161 Myosin class II heavy chain
Length = 2003
Score = 63.5 bits (153), Expect = 2e-09
Identities = 134/678 (19%), Positives = 261/678 (37%), Gaps = 90/678 (13%)
Query: 727 TDVNEKVLEPIEDIEMLPTFISSSNRLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPA 786
T++ + E +ED E S +L + N++ + G++ + S ++K
Sbjct: 959 TEMVRHLEENLEDEER------SRQKLLLEKNSIESRLKELEAQGLELEDSGNKLSKEKK 1012
Query: 787 SFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDT 846
+ E + +++ E+E ++ K K L + D + K+ R +
Sbjct: 1013 ALEERCEDLSSRLIDEVERSK-QLVKAKARLEATVAEINDELEKEKQQ---RHNAETARR 1068
Query: 847 CSSSLVNED----LNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQ 902
+ + + E+ L KT + LT+++++ E +++ + N + ++LE+ ++
Sbjct: 1069 AAETQLREEQESCLEKTRKAEELTNQLMRKESELSQISIRNDEELAARQQLEREIREIRA 1128
Query: 903 ELDTVLLES-KGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLV- 960
+LD + E+ K + A++A + ++ ES E T H +L +K +++
Sbjct: 1129 QLDDAIEETNKEKAARQKAEKARRDMAEELESYKQELEESNDKTVLHSQLKAKRDEEYAH 1188
Query: 961 ---EIEALNKNVTERLFEIKRIKDREVE--NHPIIKQLRDTLEGERAHFESQLALE--KQ 1013
++E K+ E + E+K +++E N I + R + ++A ++ E +
Sbjct: 1189 LQKQLEETVKSSEEVVEEMKAQNQKKIEELNETIDQLKRQKISADKAKSSAESDNENFRA 1248
Query: 1014 KVSNLKAALLSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTE 1073
++SN+ +A L K E + K+ E+Q+ L +N + +Q
Sbjct: 1249 ELSNIASARLEAEKKRKAAET---SLMEKDHKMREMQSNLDDLMAKLSKMNNELESIQKA 1305
Query: 1074 CSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLE------------- 1120
S L S K L+ +++ ++ + R T A L NK++ LE
Sbjct: 1306 KSADETLNSNLLKKNASLDMQLSELTEASEEDRRTRATLNNKIRQLEEDLAVAVEARDDA 1365
Query: 1121 -DVVSKISSNT--------------------------KSKLKPSSYDSQNTQRSISGGSE 1153
D KI K K K S + + + +
Sbjct: 1366 LDAQEKIEKEVKEVKSLLAEARKKLDEENREVMEELRKKKEKELSAEKERADMAEQARDK 1425
Query: 1154 VQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRR--- 1210
+++ Q ++ K+L + E E + + N T+L Q R
Sbjct: 1426 AERAKKKAIQEAEDVQKEL---TDVVAATREMERKMRKFDQQLAEERNNTLLAQQERDMA 1482
Query: 1211 IKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKR-LESTIAKMANEKADMTAKVKDL 1269
+ L ET LS E +D+VD+L KR L+ I +A+ K D V +L
Sbjct: 1483 HQMLRDAETKALVLS----NELSEKKDIVDQLEKDKRTLKLEIDNLASTKDDAGKNVYEL 1538
Query: 1270 ETALSQSKEKVDRYE----EYSSKSQKVDKPRPNGE-DPVALKETIVRLLKER------- 1317
E + E++ R E E Q D R E + A++ R L R
Sbjct: 1539 EKTKRRLDEELSRAEQQIIELEDALQLADDARSRVEVNMQAMRSEFERQLASREEDEDDR 1598
Query: 1318 -KKLTAILKNQAESKERD 1334
K LT+ ++N E E +
Sbjct: 1599 KKGLTSKIRNLTEELESE 1616
Score = 54.3 bits (129), Expect = 1e-06
Identities = 91/489 (18%), Positives = 194/489 (39%), Gaps = 56/489 (11%)
Query: 853 NEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEEL------------------- 893
+E TE++++L + E L+ + + +L+EL
Sbjct: 953 SESRKLTEMVRHLEENLEDEERSRQKLLLEKNSIESRLKELEAQGLELEDSGNKLSKEKK 1012
Query: 894 ------EKIQAKLVQELD--TVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLT 945
E + ++L+ E++ L+++K A A+ + K+K + N E AR + T
Sbjct: 1013 ALEERCEDLSSRLIDEVERSKQLVKAKARLEATVAEINDELEKEKQQRHNAETARRAAET 1072
Query: 946 AAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFE 1005
+ S +EK + E L + + E+ +I R E +QL + RA +
Sbjct: 1073 QLREEQESCLEKTR-KAEELTNQLMRKESELSQISIRNDEELAARQQLEREIREIRAQLD 1131
Query: 1006 SQL-ALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQH 1064
+ K+K + KA R ++ + + K + Q + YA Q
Sbjct: 1132 DAIEETNKEKAARQKAEKARRDMAEELESYKQELEESNDKTVLHSQLKAKRDEEYAHLQK 1191
Query: 1065 NAAKHLQTECSTYRNLLSEKKHKYNELNSKV-------ALASKQCAQLRSTNAHLRNKLQ 1117
+ +++ + ++ + K ELN + A K + S N + R +L
Sbjct: 1192 QLEETVKSSEEVVEEMKAQNQKKIEELNETIDQLKRQKISADKAKSSAESDNENFRAELS 1251
Query: 1118 SLEDVVSKISSNTKSKLKPSS-YDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSN 1176
++ +++ + K K +S + + R + + + L+ N + + K+
Sbjct: 1252 NIAS--ARLEAEKKRKAAETSLMEKDHKMREMQSNLDDLMAKLSKM---NNELESIQKAK 1306
Query: 1177 GAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLT----KLETNVGPLSVFCEKEK 1232
A ++ N + L+ ++ +L + +R TL +LE ++ ++V +
Sbjct: 1307 SADETLNSNLLKKNASLDMQLSELTEASEEDRRTRATLNNKIRQLEEDLA-VAVEARDDA 1365
Query: 1233 LSIRDVVDRLHWIKRLESTIAKMANEKAD------MTAKVKDLETALSQSKEKVDRYEEY 1286
L ++ +++ +K ++S +A+ A +K D M K E LS KE+ D E+
Sbjct: 1366 LDAQEKIEK--EVKEVKSLLAE-ARKKLDEENREVMEELRKKKEKELSAEKERADMAEQA 1422
Query: 1287 SSKSQKVDK 1295
K+++ K
Sbjct: 1423 RDKAERAKK 1431
>CE20196 [Z] KOG0161 Myosin class II heavy chain
Length = 1413
Score = 62.4 bits (150), Expect = 5e-09
Identities = 105/524 (20%), Positives = 220/524 (41%), Gaps = 77/524 (14%)
Query: 825 EDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINH 884
E + + E L L I + + + + E+L + ++ SE ++ + ++ +
Sbjct: 777 ERIEELENEKLKLEEEIQEMEIKNEEALKENLKLSMLLDREKSEKVKVQKELEE---VEK 833
Query: 885 QLREKLEELEKIQAKLVQELDTV-----LLESKGSFSAGTAKEAEVN------------- 926
Q REKL E E+ K ++E++ +LE K ++ K ++N
Sbjct: 834 QGREKLLEKEREFRKTMEEMEQNEEIFNVLERK--YNEQHKKVMKMNDVLREYERKIEQL 891
Query: 927 NKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVEN 986
N +KT+ + NE + + S +EK+++E +L + E +I+++ D E
Sbjct: 892 NMEKTD-LENENQKLRETQNRQDSHYSNLEKEVMEKSSL---IDELQNQIQKLSDENNEQ 947
Query: 987 HPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGKKL 1046
I +L LE E+A F A + + +++ + +++NE++ A D L
Sbjct: 948 RLTIAKLETALEDEKARF----ARQNNTIGDMQKLI------SELNEKI---ARFDNIAL 994
Query: 1047 EELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLR 1106
E +STR R + L E +T + ++ ++ K +EL ++C + +
Sbjct: 995 NER----NSTRKIEREKEK----LNEELTTAKEIIQKQAKKIDELK-------EECRKRK 1039
Query: 1107 STNAHLRNKLQSLE----DVVSKISSNTKSKLKPSSYDSQNTQR---SISGGSEVQQSSL 1159
+ + L KL+ E D V ++ + K +LK ++ +R + + Q+S +
Sbjct: 1040 NEASRLERKLEDKEAMMADCVKELKDSHKERLKEMEQKVEDVKRKNSKLENENSTQKSQI 1099
Query: 1160 TPAQYEQNAPKKLPK-SNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLE 1218
Q E + + S+G ++ + LT +R + L R +++ +
Sbjct: 1100 ETFQRESSVDSDYGRSSSGRLSTLGRQYSLTSIGSFSSIR-----TVGLGSRKDSISDMT 1154
Query: 1219 TNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEK--ADMTAKVKDLETALSQS 1276
+ S++ + + S D+ ++R ST M E+ ++ + + T L
Sbjct: 1155 S-----SMYSLRRRDSTYDMTSSTIGLQRSPSTSQVMEKERRILELEKEKAAINTDLQLV 1209
Query: 1277 KEKVDRYEEYSS--KSQKVDKPRPNGEDPVALKETIVRLLKERK 1318
K ++D Y+ S +S+K N + L+ET +L +K
Sbjct: 1210 KRELDVYKSQLSAVESEKESLQTANRKQSNQLQETTRQLNSAQK 1253
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 61.2 bits (147), Expect = 1e-08
Identities = 111/540 (20%), Positives = 218/540 (39%), Gaps = 81/540 (15%)
Query: 822 EKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEM------- 874
+K E + RK+ AL ++ DLN + + +L ++++ E
Sbjct: 518 QKVEQEIELRKKTEALLVETQRNLENEQKTRARDLNINDKVVSLEKQLLEMEQSYKTETE 577
Query: 875 ---------------------KIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKG 913
K+ +V + L++ EEL + A EL ++++ K
Sbjct: 578 NTQKLKKHNAELDFTVKSQEEKVRDMVDMIDTLQKHKEELGQENA----ELQALVVQEKN 633
Query: 914 SFSAGTAKEAEVNNKDKT--ESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTE 971
S E NK +T I RE+ + L+ K+ ++E + +
Sbjct: 634 LRSQLKEMHKEAENKMQTLINDIERTMCREQKAQEDNRALLEKIS----DLEKAHAGLD- 688
Query: 972 RLFEIKRIKDR---EVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGK 1028
FE+K + R EV+ H ++ R + E A+ + AL+ K++ K+A + K
Sbjct: 689 --FELKAAQGRYQQEVKAHQETEKSR-LVSREEANLQEVKALQ-SKLNEEKSARI----K 740
Query: 1029 NDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKY 1088
D + + K ++L L + +L + + + + ++ L ++ K
Sbjct: 741 ADQHSQEKE------RQLSMLSVDYRQIQLRLQKLEGECRQESEKVAALQSQLDQEHSKR 794
Query: 1089 NELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSI 1148
N L S+++L S + A LRS L+ +L + + + + ++LK + +++ R +
Sbjct: 795 NALLSELSLHSSEVAHLRSRENQLQKELSTQREAKRRFEEDL-TQLKSTHHEALANNREL 853
Query: 1149 SGGSEVQQ--SSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNM---- 1202
E +Q S L Q +N + + + I ++E + K + V + +
Sbjct: 854 QAQLEAEQCFSRLYKTQANENREESAERLS-KIEDLEEERVSLKHQVQVAVARADSEALA 912
Query: 1203 ------TVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMA 1256
TV DL++ KT+ +LE L F K + I L +K E+ + K
Sbjct: 913 RSIAEETVADLEKE-KTIKELE-----LKDFVMKHRNEINAKEAALATLKEAENELHKKL 966
Query: 1257 NEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNGEDPVALKETIVRLLKE 1316
+KA A+ +DL + +E++ SSK +++ K ++ V LK+ V L E
Sbjct: 967 GQKA---AEYEDLVQQHKKQQEELALMR--SSKDEEITKLLDKCKNEVLLKQVAVNKLAE 1021
Score = 52.8 bits (125), Expect = 4e-06
Identities = 112/556 (20%), Positives = 218/556 (39%), Gaps = 74/556 (13%)
Query: 781 VNKFPASFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPEKCE----------DVTQF 830
+N S E L TE E N KK EL F + E D Q
Sbjct: 554 INDKVVSLEKQLLEMEQSYKTETE-NTQKLKKHNAELDFTVKSQEEKVRDMVDMIDTLQK 612
Query: 831 RKEYLA-----LRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQ 885
KE L L+A + ++ S L +Q L ++I ++ + N
Sbjct: 613 HKEELGQENAELQALVVQEKNLRSQLKEMHKEAENKMQTLINDIERTMCREQKAQEDNRA 672
Query: 886 LREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLT 945
L EK+ +LEK A LD L ++G + + + Q EKS
Sbjct: 673 LLEKISDLEKAHA----GLDFELKAAQGRYQ---------------QEVKAHQETEKS-- 711
Query: 946 AAHGKLISKVEKDLVEIEALNKNVTE----RLFEIKRIKDREVENHPIIKQLRDTLEGER 1001
+L+S+ E +L E++AL + E R+ + +++E + + R ++
Sbjct: 712 ----RLVSREEANLQEVKALQSKLNEEKSARIKADQHSQEKERQLSMLSVDYRQ-IQLRL 766
Query: 1002 AHFESQLALEKQKVSNLKAALLSRHGK-----NDINEEVKPAAPLDGKKLEELQAELSST 1056
E + E +KV+ L++ L H K ++++ A L ++ +LQ ELS+
Sbjct: 767 QKLEGECRQESEKVAALQSQLDQEHSKRNALLSELSLHSSEVAHLRSRE-NQLQKELSTQ 825
Query: 1057 RLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVA---LASKQCAQLRSTNAHLR 1113
R A+ + L ST+ L+ + +L ++ L Q + R +A
Sbjct: 826 R---EAKRRFEEDLTQLKSTHHEALANNRELQAQLEAEQCFSRLYKTQANENREESAERL 882
Query: 1114 NKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGS------EVQQSSLTPAQYEQN 1167
+K++ LE+ ++S + ++ + DS+ RSI+ + E L +
Sbjct: 883 SKIEDLEE--ERVSLKHQVQVAVARADSEALARSIAEETVADLEKEKTIKELELKDFVMK 940
Query: 1168 APKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETN----VGP 1223
++ A+ + E E L + + V +++ + L + ++ +
Sbjct: 941 HRNEINAKEAALATLKEAENELHKKLGQKAAEYEDLVQQHKKQQEELALMRSSKDEEITK 1000
Query: 1224 LSVFCEKEKLSIRDVVDRL-HWIKRLESTIAKMANE---KADMTAKVKDLETALSQSKEK 1279
L C+ E L + V++L + R +S + K N+ A++ K K++ + ++
Sbjct: 1001 LLDKCKNEVLLKQVAVNKLAEVMNRRDSDLPKQKNKARSTAELRKKEKEMRRLQQELSQE 1060
Query: 1280 VDRYEEYSSKSQKVDK 1295
D++ + K Q + +
Sbjct: 1061 RDKFNQLLLKHQDLQQ 1076
>YIL149c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1679
Score = 60.8 bits (146), Expect = 1e-08
Identities = 139/694 (20%), Positives = 278/694 (40%), Gaps = 77/694 (11%)
Query: 632 ESVEVHHLQKLPPRLRYLELESPSNNFISKPLRANNRVEKLRKDELYNGSKQKRRTRGSA 691
E + H++ L +L ++ S +K L N+ +E K + T S
Sbjct: 206 EVTKSSHVENLEEKLYQMQSNYESVFTYNKFLLNQNKQLSQSVEEKVLEMKNLKDT-ASV 264
Query: 692 PDSEGSKKPLIERQIEDGNVSEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSN 751
+E SK+ +++ + D S+ T E S+ ++ E +++ I +
Sbjct: 265 EKAEFSKEMTLQKNMNDLLRSQLTSLEKDCSLRAIEKNDDNSCRNPEHTDVIDELIDTKL 324
Query: 752 RLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETNEGNSK 811
RLE N L + V+ K+ T + + P + ++I+ +
Sbjct: 325 RLEKSKN--ECQRLQNIVMDCTKEEEATMTT-------SAVSPTVGKLFSDIKVLKRQLI 375
Query: 812 KGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQ 871
K +++ + ED E+ K+ T SL +E TE+++ ++ +
Sbjct: 376 KERNQKFQLQNQLEDFI-LELEHKTPELISFKERT--KSLEHELKRSTELLETVSLTKRK 432
Query: 872 SEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKG--SFSAGTAKEAEVNNKD 929
E +I SL + + L K + L +++ +LL + ++ +++ ++ +
Sbjct: 433 QEREITSLRQKINGCEANIHSLVKQRLDLARQVKLLLLNTSAIQETASPLSQDELISLRK 492
Query: 930 KTESIN--NEQAREKSLTAAHGKLISKVEKDLVEIEALN--KNVTERL--FEIKRIKDRE 983
ES N NE + +T + + E +E LN + + ++L +E K+ K +
Sbjct: 493 ILESSNIVNENDSQAIITERLVEFSNVNELQEKNVELLNCIRILADKLENYEGKQDKTLQ 552
Query: 984 VENHPIIKQLRDT---LEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAP 1040
+ IK+ +D LE A E+++ + ++ + K + K + N A
Sbjct: 553 KVENQTIKEAKDAIIELENINAKMETRINILLRERDSYKLLASTEENKANTNSVTSMEAA 612
Query: 1041 LDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASK 1100
+ KK+ EL+AELSST++ A ++L+ E Y+ +KK + + LA +
Sbjct: 613 RE-KKIRELEAELSSTKVENSA---IIQNLRKELLIYKKSQCKKKTTLEDFENFKGLAKE 668
Query: 1101 QCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLT 1160
+ L HL+ +L+ K K SY +R+ +E+ QS +
Sbjct: 669 KERMLEEAIDHLKAELE-------------KQKSWVPSYIHVEKERA---STELSQSRIK 712
Query: 1161 PAQYEQNAPKKLPKSNGAITYIDENEILTKDI------------------LNDEVRKLNM 1202
E KL K ++I E LT+D ++ K++
Sbjct: 713 IKSLEYEI-SKLKKETA--SFIPTKESLTRDFEQCCKEKKELQMRLKESEISHNENKMDF 769
Query: 1203 TVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADM 1262
+ + Q + K + +LE N+ E+ + ++ + + I+ + + K A D
Sbjct: 770 SSKEGQYKAK-IKELENNL-------ERLRSDLQSKIQEIESIRSCKDSQLKWAQNTIDD 821
Query: 1263 T-AKVKDLETALSQSKEKVDRYEEYSSKSQKVDK 1295
T K+K L T LS + + E+ SS+ + +DK
Sbjct: 822 TEMKMKSLLTELSNKETTI---EKLSSEIENLDK 852
Score = 51.6 bits (122), Expect = 8e-06
Identities = 111/555 (20%), Positives = 225/555 (40%), Gaps = 93/555 (16%)
Query: 814 KDELHFDPEKCEDVT---QFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEII 870
K +LH E +V + ++EY ++ +D+ +N+DLNK + +
Sbjct: 102 KKQLHVSHEAMREVNDEKRVKEEYDIWQSRDQGNDS-----LNDDLNKENKLLRRKLMEM 156
Query: 871 QSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDK 930
++ ++ I+ QL+ EK +L+ + ++ E SFS T E EV K
Sbjct: 157 ENILQRCKSNAISLQLKYDTSVQEK---ELMLQSKKLIEEKLSSFSKKTLTE-EVT---K 209
Query: 931 TESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPII 990
+ + N + + + + + + + + L + + L+++V E++ E+K +KD
Sbjct: 210 SSHVENLEEKLYQMQSNYESVFTYNKFLLNQNKQLSQSVEEKVLEMKNLKD--------- 260
Query: 991 KQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRH--------GKNDINEEVKPAAPLD 1042
T E+A F ++ L+K L++ L S KND N P
Sbjct: 261 -----TASVEKAEFSKEMTLQKNMNDLLRSQLTSLEKDCSLRAIEKNDDNSCRNP----- 310
Query: 1043 GKKLEELQAELSSTRLYARAQHNAAKHLQT---ECSTYRN---LLSEKKHKYNELNSKVA 1096
+ ++ EL T+L N + LQ +C+ S +L S +
Sbjct: 311 --EHTDVIDELIDTKLRLEKSKNECQRLQNIVMDCTKEEEATMTTSAVSPTVGKLFSDIK 368
Query: 1097 LASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQ 1156
+ +Q + R+ L+N+ LED + ++ T +L +++ + + +E+ +
Sbjct: 369 VLKRQLIKERNQKFQLQNQ---LEDFILELEHKT-PELISFKERTKSLEHELKRSTELLE 424
Query: 1157 S-SLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTL- 1214
+ SLT + E+ K NG + L LDL R++K L
Sbjct: 425 TVSLTKRKQEREITSLRQKINGC---------------EANIHSLVKQRLDLARQVKLLL 469
Query: 1215 ---TKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLES------TIAKMANEKADMTAK 1265
+ ++ PLS + E +S+R +++ + + +S + + +N ++ K
Sbjct: 470 LNTSAIQETASPLS---QDELISLRKILESSNIVNENDSQAIITERLVEFSNVN-ELQEK 525
Query: 1266 VKDLETALSQSKEKVDRYEEYSSKS-QKVDKPR-PNGEDPV-------ALKETIVRLLKE 1316
+L + +K++ YE K+ QKV+ +D + A ET + +L
Sbjct: 526 NVELLNCIRILADKLENYEGKQDKTLQKVENQTIKEAKDAIIELENINAKMETRINILLR 585
Query: 1317 RKKLTAILKNQAESK 1331
+ +L + E+K
Sbjct: 586 ERDSYKLLASTEENK 600
>SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1727
Score = 60.8 bits (146), Expect = 1e-08
Identities = 234/1131 (20%), Positives = 427/1131 (37%), Gaps = 196/1131 (17%)
Query: 201 IHKHIESPFQRNSKPVSKSIVKAPNKVNFAF---ETSLNDIDLNLLTRARASSGGTPTSK 257
+ I + + NS +S+ I +++N + E+ LN+ NLL A+S + S
Sbjct: 570 VQYQISNAVKENSNTLSEQIKNLESELNSSKIKNESLLNE--RNLLKEMLATSRSSILSH 627
Query: 258 GSAAVPAAPKTKNKTDSQVSKIAN-EIQNSNKSRISKANSPIQRTTTTTSNIPSEAKELY 316
S+A K K+ +S N E+ + + I ++ S +R S + + KEL
Sbjct: 628 NSSAGNIDDKMKSIDESTRELEKNYEVYRNEMTAIQESLS--KRNQDLLSEMEAIRKELE 685
Query: 317 NMLSSRLKRRNVLFDKKGTINSENNDKTGASVKVESSHVEIIGSKRDHTHTSFMELPSMQ 376
N + + L + + E K ++ + +++ I S++D + F E
Sbjct: 686 NSKYQQQLSTDRLTNANNDV--EAFKKEAKELRSINQNLQDIISRQDQRASKFAE----- 738
Query: 377 ATIADLAKTTSLVKENSAQIEVDRNLIGPERSRKNEKEFQDLETRTSSPAKESLASPSAD 436
+L SL + L G + K EK DL RT +E L S +
Sbjct: 739 ----ELLHVNSLAER----------LKGELNASKGEK---DLRKRT----QERLISENDK 777
Query: 437 TPERKVPQLDLTSPSFDSTPGVTEKMDLKEVPSPEYPSSAGQAVQ-QSESSQISHVIQQA 495
+ + L S DL+ + + S A + V+ +SE +S +Q+
Sbjct: 778 LLAERERLMSLVS-------------DLQTFLNQQQLSDAARKVKFESEKESLSLSLQKL 824
Query: 496 EGADSGSHHGIQVESSELNIPTIFEKKDNPQAASASGTFHHVDEKQS-TEETAKLLALXX 554
+ ++ + + L +K + +S T + EKQS +E+ KLL
Sbjct: 825 KESNEKMSNDLHSLQKSL-------EKSGIEYSSRIKTL--MLEKQSLSEDNRKLLDNQQ 875
Query: 555 XXXXXXXXXXXXXHYVGDFQLLNTMKARMVGPKVAKW---KAFNKSKFKDLMKYLIAEHT 611
+ Q +T++A+ K + +A +S DL ++HT
Sbjct: 876 MMEIKLQELNGVIEL--EKQRFSTLEAKFTQQKNTSYSEREALLESSLSDLQ----SKHT 929
Query: 612 PLAARSDVSCSN----------------------DICNIRNYESVEVHHLQ--KLPPRLR 647
L ++ + S N D ++ ES+E +HL+ L R+
Sbjct: 930 SLESQYNYSLRNIEQLQAASKLAEEMVERVKTEYDEYRLQTSESLEKNHLKITSLEQRIV 989
Query: 648 YLELESPSNNFISKPLRANN--RVEKLRKDE--LYNGSKQKRRTRGSAPDSEGSKKPLIE 703
L+ E S++ + + ++ RV L ++ L N R + E K +
Sbjct: 990 ILQDEIASSSLRCENITKDSETRVALLLEENKHLNNELSSHRNAEKQHLEKENDYKQQLL 1049
Query: 704 RQIEDGNVSEKTPQEPTTSIPGETDVNE----------KVLEPIEDIEMLPTFISSSNRL 753
ED KT ++ + D K LE +ED+ + N
Sbjct: 1050 LVTED---LRKTREDYEKELLRHADARSTLQKLREDYTKALEQVEDLNKEIALKAGINES 1106
Query: 754 EPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDN---AQASTEIETNEGNS 810
+P + L V +KKQ ++ LQ N A+ ++ +
Sbjct: 1107 QPFPISEKEDPLRQEVYVLKKQNAMLLTQ---------LQSSNLNFAEITSPSPDLDSVM 1157
Query: 811 KKGKDELHFDPEKCE---DVTQFRKEYLALRASISKDDTCSSSLVNEDLNK--TEVIQNL 865
K G +L ++ ++ +++ L L K SS+ V DL + TE +
Sbjct: 1158 KLGLSDLQNHVKRISKEMEIISCQRQLLFLENKKLKRTVESSNRVIADLQRGITEKDVSS 1217
Query: 866 TSEIIQSEMKIASLVGI----NHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAK 921
TSE + ++V + N LRE LE E++ +L ++++T L +F
Sbjct: 1218 TSESVGERSNYLNMVALLNESNKSLRENLERNEEVITELREKIET-LKTDLANFRL---- 1272
Query: 922 EAEVNNKDKTES-INNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIK 980
NK++ ES + E+A K L ++ + ++ L+ + + T + R+K
Sbjct: 1273 -----NKEQLESQLQTEKAAVKKLENSNEEYKRHNQEILLSLNSS----TSTSSDASRLK 1323
Query: 981 DREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAP 1040
+ V +I++L E H +S+L K K +L+ NE +
Sbjct: 1324 NELVSKENLIEELNQ----EIGHLKSELETVKSKSEDLE------------NERAQ---- 1363
Query: 1041 LDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASK 1100
+ K+E+L EL +T+L A + + + + + + K +EL +KVA +
Sbjct: 1364 -NQSKIEQL--ELKNTKLAAAWRTKYEQVVNKSLEKHNQIRQQLSQKTSELEAKVAECHQ 1420
Query: 1101 QCAQLRSTNAHLRNKLQSLEDVVSKISSN-TKSKLKPSSYDSQNTQRSISGGSEVQQSSL 1159
QL +A QS VS N TK +L +TQR +S ++ ++
Sbjct: 1421 LNEQLNKPSATPTATTQSEPSTVSLEEFNSTKEEL-------SSTQRKLSEIMDILNTTK 1473
Query: 1160 TPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLET 1219
+ + K ++ +E E+ K ++ EV +L R K L K E
Sbjct: 1474 EELEKVRQNSNKSEGTSKDTEIPNEEEMERKKVMQQEVLRLR------SRIAKELQKNE- 1526
Query: 1220 NVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLE 1270
K+ ++D V L E+ ++ E A + A KDLE
Sbjct: 1527 -------LLRKQNQVLQDQVKALQ-----ETVVSSEEAESASVHADTKDLE 1565
>Hs15313972 [Z] KOG0161 Myosin class II heavy chain
Length = 1647
Score = 60.8 bits (146), Expect = 1e-08
Identities = 119/562 (21%), Positives = 235/562 (41%), Gaps = 89/562 (15%)
Query: 801 TEIETNEGNSKKGKDELHFDPEKCE-DVTQFRKEYLALRASIS--------KDDTCSSSL 851
+++E +K + EL K + + T + + L+A I K++ +L
Sbjct: 708 SDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGAL 767
Query: 852 VNED------LNKTEVIQNLTSEIIQS----EMKIASLVGINHQLREKLEELEKIQAKLV 901
D N +V++ L ++I + E + AS Q R+ EELE ++ +L
Sbjct: 768 ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELE 827
Query: 902 QELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVE 961
LDT TA + E+ K + E ++A E+ ++ ++
Sbjct: 828 DTLDT------------TAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATA 875
Query: 962 IEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAA 1021
+E L +E+L + KR K +N + LE + +LA E + + +KA
Sbjct: 876 LEEL----SEQLEQAKRFKANLEKN-------KQGLETD----NKELACEVKVLQQVKAE 920
Query: 1022 LLSRHGKNDINEEVKPAAPLDGKKLEELQAELS-STRLYARAQHNAAKHLQTECSTYRNL 1080
S H + ++ +V +EL A++S RL A+K LQ E L
Sbjct: 921 --SEHKRKKLDAQV-----------QELHAKVSEGDRLRVELAEKASK-LQNELDNVSTL 966
Query: 1081 LSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKIS--SNTKSKLKPSS 1138
L E + K + A +QL+ T L+ + + ++ S+I K+ L+
Sbjct: 967 LEEAEKKGIKFAKDAASLE---SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQ 1023
Query: 1139 YDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDE-- 1196
+ + ++++ QS L + KK+ G I ++E + K +L D
Sbjct: 1024 EEEEEARKNLEKQVLALQSQLA------DTKKKVDDDLGTIESLEEAK---KKLLKDAEA 1074
Query: 1197 -VRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRL----EST 1251
++L L + KT +L+ + L+V + ++ ++ + +L +S
Sbjct: 1075 LSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI 1134
Query: 1252 IAKMANEKADMTAKVKDLET-ALSQSK---EKVDRYEEYSSKSQKVDKPRPNGEDPVALK 1307
A+ A E+ A+ ++ ET ALS ++ E ++ EE+ +++++ R + ED ++ K
Sbjct: 1135 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQL---RADMEDLMSSK 1191
Query: 1308 ETIVRLLKERKKLTAILKNQAE 1329
+ + + + E +K L+ Q E
Sbjct: 1192 DDVGKNVHELEKSKRALEQQVE 1213
Score = 52.8 bits (125), Expect = 4e-06
Identities = 146/740 (19%), Positives = 293/740 (38%), Gaps = 103/740 (13%)
Query: 598 KFKDLMKYLIAEHTPLAARSDVSCSNDICNIRNYESVEVHHLQ---KLPPRLRYLELESP 654
K K LM+ IAE + A + N + IRN + V + L+ K + R ELE
Sbjct: 670 KEKKLMEDRIAECSSQLAEEEEKAKN-LAKIRNKQEVMISDLEERLKKEEKTRQ-ELEKA 727
Query: 655 SNNFISKPLRANNRVEKLRK--DEL-YNGSKQKRRTRGSAP--DSEGSKKPLIERQIEDG 709
+ +++ +L+ DEL +K++ +G+ D E K + + +
Sbjct: 728 KRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVREL 787
Query: 710 NVSEKTPQEPTTSIPGETDVNEKVLEPI-EDIEMLPTFISSSNRLEPDANTLSAHALPSS 768
QE S + EK + E++E L T LE +T +A
Sbjct: 788 QAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT------ELEDTLDTTAA------ 835
Query: 769 VIGVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPEKCEDVT 828
+Q T + A + L+ + +I+ +EL E+ E
Sbjct: 836 -----QQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELS---EQLEQAK 887
Query: 829 QFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLRE 888
+F+ + + D+ E + +V+Q + +E SE K L +L
Sbjct: 888 RFKANLEKNKQGLETDN-------KELACEVKVLQQVKAE---SEHKRKKLDAQVQELHA 937
Query: 889 KLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAH 948
K+ E ++++ +L + K +++ N+ S E+A +K + A
Sbjct: 938 KVSEGDRLRVELAE------------------KASKLQNELDNVSTLLEEAEKKGIKFAK 979
Query: 949 --GKLISKVE--KDLVEIEALNK-NVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAH 1003
L S+++ ++L++ E K N++ R+ +++ K+ E ++ R LE +
Sbjct: 980 DAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLA 1039
Query: 1004 FESQLALEKQKVSN-----------LKAALLSRHGKNDINEEVKPAAPLDGKKLEELQAE 1052
+SQLA K+KV + K L + EE A K LQ E
Sbjct: 1040 LQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQE 1099
Query: 1053 LSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKH---KYNELNSK------------VAL 1097
L + Q A +L+ + + LL+E+K +Y E + ++L
Sbjct: 1100 LDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSL 1159
Query: 1098 ASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQS 1157
A L + R Q D+ +SS K + + ++ + ++R++ E ++
Sbjct: 1160 ARALEEALEAKEEFERQNKQLRADMEDLMSS--KDDVGKNVHELEKSKRALEQQVEEMRT 1217
Query: 1158 SLTPAQYE----QNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKT 1213
L + E ++A +L + A+ E ++ T+D N+E ++L ++ R ++
Sbjct: 1218 QLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL---LIKQVRELEA 1274
Query: 1214 LTKLETNVGPLSVFCEKE-KLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETA 1272
+ E L+V +K+ ++ ++D+ ++ + + K + + A++KD +
Sbjct: 1275 ELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK---LQAQMKDYQRE 1331
Query: 1273 LSQSKEKVDRYEEYSSKSQK 1292
L +++ D S +S+K
Sbjct: 1332 LEEARASRDEIFAQSKESEK 1351
>Hs7669506 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 60.5 bits (145), Expect = 2e-08
Identities = 105/514 (20%), Positives = 217/514 (41%), Gaps = 58/514 (11%)
Query: 805 TNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLV---NEDLNKTEV 861
TN + K + +FD E + + + L AS + + S+ L N +
Sbjct: 1439 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQ 1498
Query: 862 IQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAK 921
++ L E + +I+ L + +++ ELEKI+ ++ QE K A +
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE--------KSELQAAL-E 1549
Query: 922 EAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVE----IEALNKNVTERLFEIK 977
EAE S+ +E+ + + ++ S+V++ + E I+ + +N + ++
Sbjct: 1550 EAEA-------SLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQ 1602
Query: 978 RIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKP 1037
D E+ + +L+ +EG+ E QL +N AA R+ +N
Sbjct: 1603 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQL-----NHANRMAAEALRNYRNTQAILKDT 1657
Query: 1038 AAPLDG--KKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKV 1095
LD + E+L+ +L+ A LQ E R L + + ++
Sbjct: 1658 QLHLDDALRSQEDLKEQLAMV-------ERRANLLQAEIEELRATLEQTERSRKIAEQEL 1710
Query: 1096 ALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGS--- 1152
AS++ L + N L N + LE +S+I + ++ + + +++I+ +
Sbjct: 1711 LDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMA 1770
Query: 1153 -EVQQSSLTPAQYEQNAPKKLPKSNGAITY-IDENEILTKDILNDEVRKLNMTVLDLQ-- 1208
E+++ T A E+ K L ++ + + +DE E L +++KL V +L+
Sbjct: 1771 EELKKEQDTSAHLER-MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGE 1829
Query: 1209 ---------RRIKTLTKLETNVGPLSVFCEKEK---LSIRDVVDRLHWIKRLESTIAKMA 1256
+K L K E V L+ E+++ L ++D+VD+L + A+ A
Sbjct: 1830 VESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEA 1889
Query: 1257 NEKADMT-AKVKDLETALSQSKEKVDRYEEYSSK 1289
E++++ +K + ++ L +++E+ D E +K
Sbjct: 1890 EEQSNVNLSKFRRIQHELEEAEERADIAESQVNK 1923
Score = 56.2 bits (134), Expect = 3e-07
Identities = 146/775 (18%), Positives = 302/775 (38%), Gaps = 130/775 (16%)
Query: 658 FISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIERQI----------- 706
F KPL + EK E+ N ++ +T+ +E +K L E+ +
Sbjct: 838 FKIKPLLKSAETEK----EMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL 893
Query: 707 -------EDGNVSEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNR-LEPDAN 758
+ E+ Q T I E + E V E ED E + +++ R LE + +
Sbjct: 894 QVQAEADSLADAEERCDQLIKTKIQLEAKIKE-VTERAEDEEEINAELTAKKRKLEDECS 952
Query: 759 TLSAHA--LPSSVIGVKKQPSLTTVNKFPASFEN--GLQPDNAQASTEIETNEGNSKKGK 814
L L ++ V+K+ T NK E GL A+ + E + + ++
Sbjct: 953 ELKKDIDDLELTLAKVEKEKHATE-NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1011
Query: 815 DELHFDPEKCEDVTQFRKEY-------------------------------LALRASISK 843
D+L + +K +T+ + + L L +
Sbjct: 1012 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAM 1071
Query: 844 DDTCSSSLVNEDLNKTEV-IQNLTSEI-------IQSEMKIASLVGINHQLREKLE---- 891
D ++E L K E + L S+I +Q + KI L +L E++E
Sbjct: 1072 DIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERA 1131
Query: 892 ---ELEKIQAKLVQELDTV---LLESKGSFSA----GTAKEAEVNN--KDKTESINNEQA 939
+ EK ++ L +EL+ + L E+ G+ SA +EAE +D E+ +A
Sbjct: 1132 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEA 1191
Query: 940 REKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEG 999
+L H ++++ + + ++ + + + + E+K D N + + + LE
Sbjct: 1192 TAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEK 1251
Query: 1000 ERAHFESQLAL------EKQKVSN----LKAALLSRHG--------KNDINEEVKPAAPL 1041
E QL+ E+Q++ N +A L + G K+ + ++
Sbjct: 1252 MCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQA 1311
Query: 1042 DGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQ 1101
+++EEL+ +L A +A + + +C R E++ EL ++ A+ +
Sbjct: 1312 FTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSE 1371
Query: 1102 CAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTP 1161
AQ R+ + + +Q E++ K KL D++ +++ + +
Sbjct: 1372 VAQWRT--KYETDAIQRTEEL-----EEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQR 1424
Query: 1162 AQYE-QNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETN 1220
Q E ++ + ++N A +D+ + IL + +K T +L+ K L T
Sbjct: 1425 LQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTE 1484
Query: 1221 VGPLSVFCEKE--------------KLSIRDVVDRL----HWIKRLESTIAKMANEKADM 1262
+ + E+ + I D+ +++ I LE ++ EK+++
Sbjct: 1485 LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSEL 1544
Query: 1263 TAKVKDLETALSQSKEKVDRYE-EYSSKSQKVDKPRPNGEDPV-ALKETIVRLLK 1315
A +++ E +L + K+ R + E + +VD+ ++ + +K +R+++
Sbjct: 1545 QAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVE 1599
>Hs8923940 [Z] KOG0161 Myosin class II heavy chain
Length = 1941
Score = 60.1 bits (144), Expect = 2e-08
Identities = 103/512 (20%), Positives = 203/512 (39%), Gaps = 54/512 (10%)
Query: 805 TNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLV---NEDLNKTEV 861
TN + K + +FD E + + + L AS + + + L N +
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
Query: 862 IQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQE---LDTVLLESKGSFSAG 918
++ L E + +I+ L + +++ ELEKI+ ++ QE L L E++ S
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
Query: 919 TAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKR 978
K + + L ++ K+ + EI+ L +N + ++
Sbjct: 1561 EGKILRI---------------QLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605
Query: 979 IKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPA 1038
D E+ + +L+ +EG+ E QL +N AA R+ +N
Sbjct: 1606 TLDAEIRSRNDAIRLKKKMEGDLNEMEIQL-----NHANRMAAEALRNYRNTQGILKDTQ 1660
Query: 1039 APLDG--KKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVA 1096
LD + E+L+ +L+ A LQ E R L + + ++
Sbjct: 1661 IHLDDALRSQEDLKEQLAMV-------ERRANLLQAEIEELRATLEQTERSRKIAEQELL 1713
Query: 1097 LASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGS---- 1152
AS++ L + N L N + LE +S++ + L+ + + +++I+ +
Sbjct: 1714 DASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAE 1773
Query: 1153 EVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQ---- 1208
E+++ T A E+ +DE E L +++KL V +L+
Sbjct: 1774 ELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 1833
Query: 1209 -------RRIKTLTKLETNVGPLSVFCEKEK---LSIRDVVDRLHWIKRLESTIAKMANE 1258
+K L K E V L+ E+++ L ++D+VD+L + A+ A E
Sbjct: 1834 SEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEE 1893
Query: 1259 KADMT-AKVKDLETALSQSKEKVDRYEEYSSK 1289
+++ AK + L+ L +++E+ D E +K
Sbjct: 1894 QSNTNLAKFRKLQHELEEAEERADIAESQVNK 1925
Score = 53.1 bits (126), Expect = 3e-06
Identities = 155/730 (21%), Positives = 283/730 (38%), Gaps = 120/730 (16%)
Query: 658 FISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIERQIE---------- 707
F KPL + EK E+ ++ ++ + SE +K L E+ +
Sbjct: 840 FKIKPLLKSAETEK----EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQL 895
Query: 708 ------DG--NVSEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNR-LEPDAN 758
+G + E+ Q T I E + E V E ED E + +++ R LE + +
Sbjct: 896 QVQAEAEGLADAEERCDQLIKTKIQLEAKIKE-VTERAEDEEEINAELTAKKRKLEDECS 954
Query: 759 TLSAHA--LPSSVIGVKKQPSLTTVNKFPASFEN--GLQPDNAQASTEIETNEGNSKKGK 814
L L ++ V+K+ T NK E GL A+ + E + + ++
Sbjct: 955 ELKKDIDDLELTLAKVEKEKHATE-NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1013
Query: 815 DELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNE-----DLNKTEVIQNLTSEI 869
D+L + +K +T K + L + D SL E DL + + + L ++
Sbjct: 1014 DDLQAEEDKVNTLT---KAKIKLEQQV---DDLEGSLEQEKKLRMDLERAK--RKLEGDL 1065
Query: 870 IQSEMKIASLVGINHQLREKLE----ELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEV 925
++ I + QL EKL+ E+ +Q+K+ E ++ G KE +
Sbjct: 1066 KLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE------QALGIQLQKKIKELQA 1119
Query: 926 NNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFE--------IK 977
++ E I E+A +K EK ++ + ++ERL E I+
Sbjct: 1120 RIEELEEEIEAERASR-----------AKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1168
Query: 978 RIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKP 1037
K RE E +++R LE E+ A ++K ++ A L + D + VK
Sbjct: 1169 MNKKREAE----FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQI---DNLQRVKQ 1221
Query: 1038 AAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVAL 1097
K+ E++ E+ A +L+ C T + LSE K K E +
Sbjct: 1222 KLE---KEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278
Query: 1098 ASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKS------KLKPSSYDSQNTQRSISGG 1151
+ Q +L++ + +L E +VS++S ++ +LK + + +++
Sbjct: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
Query: 1152 --SEVQQSSLTPAQYEQNAPKK------LPKSNGAI----TYIDENEILTKDILNDEVRK 1199
S L QYE+ K L K+N + T + + I + L + +K
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
Query: 1200 LNMTVLDLQRRIKTLTKLETNVGPLSVFC---EKEKLSIRDVVDRLHWIKRLESTIAKMA 1256
L + L E +V ++ C EK K +++ V+ L + +E T A
Sbjct: 1399 L----------AQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDL--MLDVERTNAAC- 1445
Query: 1257 NEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNGEDPVALKETIVRLLKE 1316
A + K ++ + L++ K+K + SQK + R G + +K L +
Sbjct: 1446 ---AALDKKQRNFDKILAEWKQKCEETHAELEASQK--EARSLGTELFKIKNAYEESLDQ 1500
Query: 1317 RKKLTAILKN 1326
+ L KN
Sbjct: 1501 LETLKRENKN 1510
>Hs13124879 [Z] KOG0161 Myosin class II heavy chain
Length = 1972
Score = 59.7 bits (143), Expect = 3e-08
Identities = 135/687 (19%), Positives = 262/687 (37%), Gaps = 81/687 (11%)
Query: 699 KPLIE--RQIEDGNVSE----KTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNR 752
KPL++ RQ E+ E KT + + ++ +K + E+ +L + +
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 901
Query: 753 LEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENG------LQPDN---AQASTEI 803
L +A + + KKQ +++ A E LQ + AQ ++
Sbjct: 902 LYAEAEEMRVR------LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 804 ETNEGNSKKGKDELHFDPEKCE-DVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVI 862
E + + +L + E + + E L + D ++ L E E I
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM-------DDQNNKLSKERKLLEERI 1008
Query: 863 QNLTSEIIQSEMKIASLVGINHQLREKLEELE---KIQAKLVQELDTVLLESKGSFS--- 916
+LT+ + + E K +L + ++ + ELE K + K QEL+ + + +G S
Sbjct: 1009 SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFH 1068
Query: 917 ------AGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNV- 969
E ++ K E + AR A + K+ + I L +++
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLD 1128
Query: 970 TERLFEIKRIKDRE---VENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRH 1026
+ER K K + E + +L DTL+ E + A +Q+V+ LK AL
Sbjct: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR-AKREQEVTVLKKALDEET 1187
Query: 1027 GKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQT----------ECST 1076
++ +V+ + +EEL +L + RA+ N K+ QT E
Sbjct: 1188 RSHEA--QVQEMRQKHAQAVEELTEQLEQ---FKRAKANLDKNKQTLEKENADLAGELRV 1242
Query: 1077 YRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKIS---SNTKSK 1133
E +HK +L ++V +C+ A L +K+ L++ V ++ + + K
Sbjct: 1243 LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1302
Query: 1134 LKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDIL 1193
+ D + + E+ Q ++L + ++ + E+ K L
Sbjct: 1303 AIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1362
Query: 1194 NDEVRKLNMTVLDLQRRIK----TLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLE 1249
+ LN+ + D +++++ T+ LE G E E L+ + ++ +LE
Sbjct: 1363 ERHISTLNIQLSDSKKKLQDFASTVEALEE--GKKRFQKEIENLT-QQYEEKAAAYDKLE 1419
Query: 1250 STIAKMANEKADMTAKVKDLETALSQSKEKVDRYE----EYSSKSQKVDKPRPNGEDPVA 1305
T ++ E D+ + + +S ++K +++ E + S K R E
Sbjct: 1420 KTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
Query: 1306 LKETIVRLLKERKKLTAILKNQAESKE 1332
KET + L L+ E+KE
Sbjct: 1480 EKET------KALSLARALEEALEAKE 1500
>Hs13124875 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 59.7 bits (143), Expect = 3e-08
Identities = 135/687 (19%), Positives = 262/687 (37%), Gaps = 81/687 (11%)
Query: 699 KPLIE--RQIEDGNVSE----KTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNR 752
KPL++ RQ E+ E KT + + ++ +K + E+ +L + +
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 901
Query: 753 LEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENG------LQPDN---AQASTEI 803
L +A + + KKQ +++ A E LQ + AQ ++
Sbjct: 902 LYAEAEEMRVR------LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 804 ETNEGNSKKGKDELHFDPEKCE-DVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVI 862
E + + +L + E + + E L + D ++ L E E I
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM-------DDQNNKLSKERKLLEERI 1008
Query: 863 QNLTSEIIQSEMKIASLVGINHQLREKLEELE---KIQAKLVQELDTVLLESKGSFS--- 916
+LT+ + + E K +L + ++ + ELE K + K QEL+ + + +G S
Sbjct: 1009 SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFH 1068
Query: 917 ------AGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNV- 969
E ++ K E + AR A + K+ + I L +++
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLD 1128
Query: 970 TERLFEIKRIKDRE---VENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRH 1026
+ER K K + E + +L DTL+ E + A +Q+V+ LK AL
Sbjct: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR-AKREQEVTVLKKALDEET 1187
Query: 1027 GKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQT----------ECST 1076
++ +V+ + +EEL +L + RA+ N K+ QT E
Sbjct: 1188 RSHEA--QVQEMRQKHAQAVEELTEQLEQ---FKRAKANLDKNKQTLEKENADLAGELRV 1242
Query: 1077 YRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKIS---SNTKSK 1133
E +HK +L ++V +C+ A L +K+ L++ V ++ + + K
Sbjct: 1243 LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1302
Query: 1134 LKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDIL 1193
+ D + + E+ Q ++L + ++ + E+ K L
Sbjct: 1303 AIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1362
Query: 1194 NDEVRKLNMTVLDLQRRIK----TLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLE 1249
+ LN+ + D +++++ T+ LE G E E L+ + ++ +LE
Sbjct: 1363 ERHISTLNIQLSDSKKKLQDFASTVEALEE--GKKRFQKEIENLT-QQYEEKAAAYDKLE 1419
Query: 1250 STIAKMANEKADMTAKVKDLETALSQSKEKVDRYE----EYSSKSQKVDKPRPNGEDPVA 1305
T ++ E D+ + + +S ++K +++ E + S K R E
Sbjct: 1420 KTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
Query: 1306 LKETIVRLLKERKKLTAILKNQAESKE 1332
KET + L L+ E+KE
Sbjct: 1480 EKET------KALSLARALEEALEAKE 1500
>YNL250w [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC superfamily
Length = 1312
Score = 58.5 bits (140), Expect = 7e-08
Identities = 114/531 (21%), Positives = 210/531 (39%), Gaps = 80/531 (15%)
Query: 807 EGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLT 866
E N K +H E E + F+ S+S D+ + L N K E +Q+
Sbjct: 438 EYNKKDRSKLIHDSEELAEKLKSFK--------SLSTQDSLNHELENLKTYK-EKLQSWE 488
Query: 867 SEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGS---FSAGTAKEA 923
SE I + +N ++ EK E+ ++ ++ + D ++ ++ + G K++
Sbjct: 489 SENI--------IPKLNQKIEEKNNEMIILENQIEKFQDRIMKTNQQADLYAKLGLIKKS 540
Query: 924 EVNNKDK----TESINNE-----------QAREKSLTAAHGKLISKVEKDLV----EIEA 964
D+ TE + N+ + + L KL ++K++ ++
Sbjct: 541 INTKLDELQKITEKLQNDSRIRQVFPLTQEFQRADLEMDFQKLFINMQKNIAINNKKMHE 600
Query: 965 LNKNVTERLFEI----KRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKA 1020
L++ T L+ + K ++D + +I+ L + L + E LE+ ++S K
Sbjct: 601 LDRRYTNALYNLNTIEKDLQDNQKSKEKVIQLLSENLPEDCTIDEYNDVLEETELS-YKT 659
Query: 1021 ALLSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAA--KHLQTECSTYR 1078
AL N ++ +K E+ S L +R N + L E T
Sbjct: 660 ALE--------NLKMHQTTLEFNRKALEIAERDSCCYLCSRKFENESFKSKLLQELKTKT 711
Query: 1079 NLLSEKKHKYNELNSK-----VALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSK 1133
+ EK K N K + L K L S N + N + LE + + +KSK
Sbjct: 712 DANFEKTLKDTVQNEKEYLHSLRLLEKHIITLNSINEKIDNSQKCLEKAKEE-TKTSKSK 770
Query: 1134 LKPSSYDSQNTQRSISGGSEVQQSSLTPA----QYEQNAPKKLPKSNGAITY------ID 1183
L DS + E+ +S + P Y + K L S+ I+
Sbjct: 771 LDELEVDSTK----LKDEKELAESEIRPLIEKFTYLEKELKDLENSSKTISEELSIYNTS 826
Query: 1184 ENEILTKDILNDEVRKLNMTVLDLQRRIKTLT-----KLETNVGPLSVFCEKEKLSIRDV 1238
E+ I T D L D+ RK+N ++ +L++ I L K+ N +++ EKE L++ ++
Sbjct: 827 EDGIQTVDELRDQQRKMNDSLRELRKTISDLQMEKDEKVRENSRMINLIKEKE-LTVSEI 885
Query: 1239 VDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSK 1289
L + ++ +I D+ ++VK+LE + K K D + K
Sbjct: 886 ESSLTQKQNIDDSIRSKRENINDIDSRVKELEARIISLKNKKDEAQSVLDK 936
>Hs11024712 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 58.5 bits (140), Expect = 7e-08
Identities = 148/694 (21%), Positives = 266/694 (38%), Gaps = 114/694 (16%)
Query: 658 FISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIERQI---EDGN---- 710
F KPL + EK E+ N ++ +T+ +E +K L E+ + ++ N
Sbjct: 838 FKIKPLLKSAETEK----EMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL 893
Query: 711 -----------VSEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNR-LEPDAN 758
E+ Q T I E + E V E ED E + +++ R LE + +
Sbjct: 894 QVQAEADALADAEERCDQLIKTKIQLEAKIKE-VTERAEDEEEINAELTAKKRKLEDECS 952
Query: 759 TLSAHA--LPSSVIGVKKQPSLTTVNKFPASFEN--GLQPDNAQASTEIETNEGNSKKGK 814
L L ++ V+K+ T NK E GL A+ + E + + ++
Sbjct: 953 ELKKDIDDLELTLAKVEKEKHATE-NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1011
Query: 815 DELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNE-----DLNKTEVIQNLTSEI 869
D+L + +K +T+ + + L + D SL E DL + + + L ++
Sbjct: 1012 DDLQMEEDKVNTLTKAKTK---LEQQV---DDLEGSLEQEKKLCMDLERAK--RKLEGDL 1063
Query: 870 IQSEMKIASLVGINHQLREKLE----ELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEV 925
++ QL EKL+ E+ +Q K+ E + K KE +
Sbjct: 1064 KLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQK------KIKELQA 1117
Query: 926 NNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFE--------IK 977
++ E I E+A +K EK ++ + ++ERL E I+
Sbjct: 1118 RIEELEEEIEAERASR-----------AKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1166
Query: 978 RIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKN-DINEEVK 1036
K RE E K RD E H + AL K+ ++ + GK D + VK
Sbjct: 1167 LNKKREAEFQ---KMRRDLEESTLQHEATAAALRKKHADSV-----AELGKQIDSLQRVK 1218
Query: 1037 PAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVA 1096
K+ EL+ E++ A + + C T + LSE K K E +
Sbjct: 1219 QKLE---KEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLIN 1275
Query: 1097 LASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKS------KLKPSSYDSQNTQRSISG 1150
S Q A+L + + +L + +VS++S ++ +LK + + +++
Sbjct: 1276 ELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAH 1335
Query: 1151 G--SEVQQSSLTPAQYEQNAPKK------LPKSNGAI----TYIDENEILTKDILNDEVR 1198
S L QYE+ K + K+N + T + + I + L + +
Sbjct: 1336 ALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395
Query: 1199 KLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANE 1258
KL + D + ++ V EK K +++ V+ L I S A +A +
Sbjct: 1396 KLAQRLQDAEEHVEA-------VNSKCASLEKTKQRLQNEVEDL-MIDVERSNAACIALD 1447
Query: 1259 KADMTAKVKDLETALSQSKEKVDRYEEYSSKSQK 1292
K K ++ + L++ K+K + + SQK
Sbjct: 1448 K-----KQRNFDKVLAEWKQKYEETQAELEASQK 1476
Score = 53.9 bits (128), Expect = 2e-06
Identities = 88/461 (19%), Positives = 182/461 (39%), Gaps = 74/461 (16%)
Query: 858 KTEVIQNLTSEIIQSEMKIASLVGINHQ----LREKLEELEKIQAKLVQELDTVLLESKG 913
+T+ IQ T E+ +++ K+A + + + K LEK + +L E++ ++++ +
Sbjct: 1380 ETDAIQR-TEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVER 1438
Query: 914 SFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNK---NVT 970
S +A A + + N DK A K K E+ E+EA K +++
Sbjct: 1439 SNAACIALDKKQRNFDKV--------------LAEWK--QKYEETQAELEASQKESRSLS 1482
Query: 971 ERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKND 1030
LF++K + +++ +K+ L+ E + Q+A G
Sbjct: 1483 TELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIA----------------EGGKH 1526
Query: 1031 INEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEK------ 1084
I+E K LD +K ELQ L + +Q E + ++ + K
Sbjct: 1527 IHELEKVKKQLDHEK-SELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDE 1585
Query: 1085 ---KHKYNELNSKVALASKQCAQLRSTNAHLR---------NKLQSLEDVVSKISSNTKS 1132
+ K N L ++ S A++RS N LR N+++ + ++ ++
Sbjct: 1586 ELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALR 1645
Query: 1133 KLKPSSYDSQNTQ----RSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEIL 1188
L+ + ++TQ +I G ++++ + ++ + ++ + +
Sbjct: 1646 NLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKM 1705
Query: 1189 TKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFC-----------EKEKLSIRD 1237
+ L D ++ + I T KLET++ + EK K +I D
Sbjct: 1706 AEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITD 1765
Query: 1238 VVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKE 1278
+K+ + T A + K +M VKDL+ L ++++
Sbjct: 1766 AAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLGEAEQ 1806
>CE22238 [S] KOG0992 Uncharacterized conserved protein
Length = 734
Score = 58.2 bits (139), Expect = 9e-08
Identities = 118/516 (22%), Positives = 204/516 (38%), Gaps = 101/516 (19%)
Query: 842 SKDDTCSSSLVNEDL-NKTEVIQNLTSEIIQSEMKIASLVGINHQLREKL---------- 890
++DD ++ V L +K +Q E ++S+ N + REKL
Sbjct: 31 NEDDVIPTTAVENSLYSKCNAVQEQEFERLESQ---------NAEYREKLLRTIRERDLN 81
Query: 891 -EELEKIQAKLVQELDTVL-------LESKGSFSAGTAKEAEVNNKDKTESINNEQAREK 942
E L+ +Q + +ELD + ++ K + G A+EA N K S A ++
Sbjct: 82 EELLKNVQNQHKKELDAQVRRIRELEVQLKTTTDRGLAQEAHFNVTTKEMSQKFNLALQQ 141
Query: 943 SLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGER- 1001
+ A + D + EA+ K R E+ +++D + +K +++ LE R
Sbjct: 142 ATKKAE-------QCDKEKNEAVVKYAM-REGEMMKLRDEISKKDSNMKVIKEELEAARK 193
Query: 1002 AHFESQLALEKQKVSNLKAALLS-RHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYA 1060
A + L ++ V NLK + +H + D +K A K++E L + LS ++
Sbjct: 194 AQSQENLDDLEKTVQNLKVEIEKLKHERFDFENRMKIAE----KRVESLSSNLSESKQQG 249
Query: 1061 ---RAQHNAAKH-----------LQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLR 1106
R Q AK LQT + L E +H L + + + +
Sbjct: 250 DMLRKQLIQAKDDKHIIQQYEVKLQTSTAELERRLRESEHDVERLRTSQLEMATKFEEAS 309
Query: 1107 STNAHLRNKLQSLEDVVSKISSNTK-------------SKLKPSSYDSQNTQRSISGGSE 1153
N L +K+ L+D +S K S ++ SS+ + T++ E
Sbjct: 310 RENTDLLSKIDILQDQLSLEEDRRKLCEEQIDRLKGVESFVESSSHRIEETEKERETAEE 369
Query: 1154 V-QQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKL--NMTVLDLQRR 1210
+Q+ L A+Y + K L K +T + N L + + ++E + N T+ LQ
Sbjct: 370 DREQAELEAAEYREQVEKML-KLTQELT--ERNMELQRKLKDEEGKNTSHNSTIEKLQVE 426
Query: 1211 IKTLTKL-----ETNVGPLSVFCEKEKLSI----------------RDVVDRLHWIKRLE 1249
+ T +L ETN L + E E L RD D ++LE
Sbjct: 427 LTTSLELCKSFEETN---LKISEELENLKTEMQKPVTLESLEENFYRDKYDEAS--RKLE 481
Query: 1250 STIAKMANEKADMTAKVKDLETALSQSKEKVDRYEE 1285
T AK+A EK + +A K L + K ++ Y +
Sbjct: 482 QTEAKLAEEKNNFSAFKKKTSATLKELKSELSGYRK 517
>7292701_2 [S] KOG4415 Uncharacterized conserved protein
Length = 1643
Score = 58.2 bits (139), Expect = 9e-08
Identities = 149/725 (20%), Positives = 273/725 (37%), Gaps = 87/725 (12%)
Query: 659 ISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIERQIEDGNVSEKTPQE 718
++KP + N+ K + +G+ + T + ++ +KK +Q G VSEK P++
Sbjct: 550 LNKP-KGNSNNNKTASQKSGSGTSEDEATT-TITLAKSAKKAKNNKQKTSGKVSEKKPEQ 607
Query: 719 PTTSIPGETDVNEKV-LEPIEDIEMLPTFISSSNRLEPDANTLSAHALPSSVIGVKKQPS 777
+ EKV +E E+ E + + E D++ S HA S++ K +
Sbjct: 608 TNLA-------EEKVAVEKEENEERAVPMVKKTINKEQDSDAESDHA--DSLLANKSSIA 658
Query: 778 LTTVNKFPASFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPEKCEDVTQFRKE---- 833
V+ A GL ++ + E E +G DE +P K +K+
Sbjct: 659 AVMVSSASA---QGLSLHVEMSAADAEQGEDEEIEGLDE---EPPKTMSKDNKKKQKPGD 712
Query: 834 -YLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSE------------IIQSEMKIASLV 880
+ K+ L ++ + +Q E ++ E K+
Sbjct: 713 AVATMTIDKEKEKAKEKELKLKEKEREAKLQEKEKEEKLKLKEREESLRMEREEKLKEEK 772
Query: 881 GINHQLREKLEELEKIQAKLVQE-LDTVLLESKGSFSAGTAKEAEVNNKDK--TESINNE 937
+ EKL+E EKI+ K +E L L+ K KE E K+K E + E
Sbjct: 773 IKEKEREEKLKE-EKIKEKQREEKLKEEKLKEKEREERMKEKEREEKAKEKQREEKLREE 831
Query: 938 QAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTL 997
+ +EK K+++ L E + K E+L + + K RE E IK+
Sbjct: 832 KIKEKERE-------EKLKEKLREEKIKEKEKEEKLRKEREEKMREKEREEKIKEKERVE 884
Query: 998 EGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTR 1057
+ + E +L EK++ K LL + K + E K +KL+E + E R
Sbjct: 885 KIKEKEREEKLKKEKEEKLKEKEELLKKKEKEEKEREEKLKEKERQEKLKEKEREEKLKR 944
Query: 1058 LYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQ 1117
Q + + + E+ K +L +V L K+ QL+ L+ K +
Sbjct: 945 ETEERQREKEREEKLK-------EKERAEKLKDLEKEVKLKEKE-EQLKEKEKELKLKEK 996
Query: 1118 SLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNG 1177
+D V + + +S+ S N R + + + PA + + K P
Sbjct: 997 KEKDKVKEKEKSLESEKLLISATVSNPWRRVVEDTPPK----LPAVQDYPSLGKKPTKAS 1052
Query: 1178 AITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLE--TNVGPLSV--FCEKEKL 1233
DE + L +++N T D +K L L + PL V +KE +
Sbjct: 1053 PEKKRDEKLL---PGLTTPPKEVNDTFEDFLSGLKPLEALPPLPALEPLEVKEDSKKESV 1109
Query: 1234 SIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKV 1293
S+ + L + I+ + + + +++++ R E + + V
Sbjct: 1110 SLINFESPLQETASIPRKISPPPRGFTEQNLILALCGSLHYENEQERIRETEAEVQPEVV 1169
Query: 1294 DKPRP---------------------NGEDPVALKETIVRLLKERKKLTAI-LKNQAESK 1331
P P E+ V ++E + +L K+ K+L + L+ Q + +
Sbjct: 1170 TTPEPVYITLDTLALQKSTSTSNNSSGSEEIVVMEEPVKKLSKKHKRLKQLQLQQQQQQR 1229
Query: 1332 ERDPN 1336
ER+P+
Sbjct: 1230 EREPD 1234
>7303561 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2346
Score = 57.8 bits (138), Expect = 1e-07
Identities = 152/833 (18%), Positives = 324/833 (38%), Gaps = 111/833 (13%)
Query: 576 LNTMKARMVGPKVAKWKAFNKSKFKDLMKYLIAEHTPLAARSDVSCSNDICNIRNYESVE 635
L T K V ++K + K F K + ++T S++ ++ + +
Sbjct: 588 LLTQKNNTVTTLLSKCDRYKKLYFAAQKK--LGQNTVDLDDSNLEPNDSALDTSEQPAAN 645
Query: 636 VHHLQKLPPRLRYLE--LESPSNNFISKPLRANNRVEKLRKD-----ELYNGSKQKRRTR 688
+KL R+R LE LE + S + + RK+ E ++ +++ R
Sbjct: 646 FEESRKLEKRVRQLEQQLEGEVKKYASLKENYDYYTSEKRKNDALAQEQFDSMRKEVREL 705
Query: 689 GSAPDSEGSKKPLIERQIEDGNVSEKTPQEPTTSIPGETDVNEK-VLEPIEDIEMLPTFI 747
S+ + + QIE + + T ++ T++ T EK +++ + + +L +
Sbjct: 706 TSSNCKLMNTTEFQKEQIELLHKNIGTYKQQVTTLEERTKNYEKTIIKHEQTVHLLKDEM 765
Query: 748 SSSNRLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETN- 806
+++R A+ A +L ++ S + K E Q + I+TN
Sbjct: 766 MAAHRKHAAADA-EAQSLRQENRILRDTSSRLQIEKETYHREQQSQSLLLNSLEFIKTNL 824
Query: 807 EGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLT 866
E + +G+ L ++ +D +E A R +++ +NE + E L
Sbjct: 825 ERSEMEGRQRLE---QRLDDTV---RELAAQRRHFQEEEEKFRESINEFKRQAETAIKLK 878
Query: 867 SEIIQSEMKI-ASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEV 925
E Q K A L + +L EK+ ++ ++ KL + L L ++ + + A+E E+
Sbjct: 879 DEEKQLADKWQAELTSVREELAEKVNKVNELSKKLQEVLTPTLNDNPITAANKRAREFEL 938
Query: 926 NNKDKT---ESINNEQARE------------------KSLTAAHGKLISKVEKDLVEIEA 964
T ES+ E A+ K L HG+L++K E+++ ++ +
Sbjct: 939 KLDQATVEIESLTKELAKTREHGEQFYKMSQSAESEIKRLHELHGELVAKQEEEIKKLRS 998
Query: 965 LNKNVTERL--FEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAAL 1022
+ R+ E + + E + Q G+ + L +K++ +
Sbjct: 999 SEAELKTRISDLEAEAMLSNVTEQSKTVNQ-----SGQLKSAQDDLKSLLEKLTEANCTI 1053
Query: 1023 LSRHGKNDINEEVKPAAPL-----------DGKKLEELQAELSSTRLYARAQHNAAKHLQ 1071
+ +N E AA + D ++L +AE + + LQ
Sbjct: 1054 RTLRSENTSLVESLNAAEVKYANGMIQHSADIQELTRYKAEFFKANDELNQLKSGRESLQ 1113
Query: 1072 TECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTK 1131
+ Y LL L+ + + K+ A L + N++L +++++L ++ ++S ++
Sbjct: 1114 ---AAYDELLRSNAEAQKLLDKEREESEKRVADLHALNSNLHDQIEALASKLAVLASQSQ 1170
Query: 1132 SKLKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQN-------------------APKKL 1172
+ +S + ++ G + S LT A+ +N A +
Sbjct: 1171 NP------NSSLNESAMDGDQSLNASGLTAAEEGRNNEQLLKIIKFLRKEKDLFAAKLDI 1224
Query: 1173 PKSNGAITYIDENEILTKDI------LNDEVRKLNMTVLDLQRRIKTLTKLET--NVGPL 1224
K+ A I E+ I K + LN E K V+ + + L K+ET +
Sbjct: 1225 LKAENA-RLISEHAIQQKKVDELNGYLNQERAKSQTDVVSANKHEEVLRKIETLNAITDS 1283
Query: 1225 SVFCEKEK----LSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKV 1280
+ +E+ L + ++ DR I +E + + ++T+K++++ + + +
Sbjct: 1284 NRILREERNALTLRVAELTDR---ISSVEKELFPLQCSNKELTSKIEEINVENTSLRTEA 1340
Query: 1281 DRYEEYSSKSQKVDKPRPNGEDPVALKETIVRLLKERKKLTAILKNQAESKER 1333
++ + + + V+K N E+ RL ER+ L +L + E ++
Sbjct: 1341 IKWRQRA--NALVEKSNRNPEE-------FKRLQAEREHLAKLLTAEKELNKK 1384
>Hs20532997 [Z] KOG0161 Myosin class II heavy chain
Length = 975
Score = 57.0 bits (136), Expect = 2e-07
Identities = 85/419 (20%), Positives = 178/419 (42%), Gaps = 64/419 (15%)
Query: 951 LISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFES--QL 1008
++ K EK+ E KN+TE + E N I K R + AH ++ L
Sbjct: 1 MLVKSEKEKRTTEHKVKNLTEEV---------EFLNEDISKLNRAAKVVQEAHQQTLDDL 51
Query: 1009 ALEKQKVSNLKAALLSRHGKND----INEEVKPAAPLDGKKLEELQAELSSTRLYARAQH 1064
+E++K+S+L A L + D E+ + A ++L +L+ L R
Sbjct: 52 HMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLE 111
Query: 1065 NAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVS 1124
++ +HL E L +K+ + +++NSKV AQL+ T L+ +++ L++ +
Sbjct: 112 SSQRHLAEE-------LRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKL- 163
Query: 1125 KISSNTKSKLKPSSYD------SQNTQRSISGGSEVQQSSLTPAQ--------------- 1163
+ T++K++ D N + GGS + Q +T Q
Sbjct: 164 EAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEAT 223
Query: 1164 --YEQNAPKKLPKSNGAITYID---ENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLE 1218
+E + + ++ ++ EN K L + L + V DL R++ +T+ +
Sbjct: 224 LHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAK 283
Query: 1219 TNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIA----KMANEKADMTAKVKDLETALS 1274
N L E+ + + +L + +L + +A K+ +E + ++++ E ++
Sbjct: 284 ANAEKLCTLYEER---LHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALIN 340
Query: 1275 Q-SKEKVDRYEEYSSKSQKVDKPRPNGEDPVALKETIVRLLKERKKLTAILKNQAESKE 1332
Q S+EK S+ +++++ R E + + L++ ++ +L+ Q E ++
Sbjct: 341 QLSREK-------SNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQ 392
>CE21149 [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC superfamily
Length = 1298
Score = 56.6 bits (135), Expect = 3e-07
Identities = 93/466 (19%), Positives = 198/466 (41%), Gaps = 61/466 (13%)
Query: 885 QLREKLEELEKIQAKLVQEL----------DTVLLESKGSFSAGTAKEAEVNNKDKTESI 934
++ EKLE L K K ++L D+ + ESK S+G + + K K E I
Sbjct: 624 EVSEKLENLRKRLKKARKDLAPLSAKSNLYDSYIEESK---SSGCCPLCDRDFKTKKE-I 679
Query: 935 NNEQAREKSLTAAHG-------KLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENH 987
N + +++T + KL+SK+EK+ + I E +K +K+
Sbjct: 680 NEFSKKLENMTLSFPTEQEELEKLVSKLEKEEIIIVKAEGQANELQRIVKELKE------ 733
Query: 988 PIIKQLRDTLEGERAHFESQLALEKQKVSNLKAAL-LSRHGKNDIN--EEVKPAAPLDGK 1044
+++ L E A +S L+ ++++ + A L L+ + D+ +++ + K
Sbjct: 734 --VREKNRKLSTEMAEEKSNLSKNEKQLETVNAKLKLAEDLQTDVGVIQQLYEQTEENEK 791
Query: 1045 KLEELQAE------LSSTRLYARAQHNAAKHLQ--------TECSTYRNLLSEKKHKYNE 1090
+ E+L +E LS T L + + ++ + +CS RN L + K NE
Sbjct: 792 RYEQLVSESDSSDGLSYTELRKKVEDKDEEYRKIVQEGEELQKCSEERNKL---QSKLNE 848
Query: 1091 LNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISG 1150
L + + AQ + L K++ +++ ++ IS L + + + R++S
Sbjct: 849 LGTHRVSLGEAAAQAGAFAEQLETKIKEIQECITAISQKRNEDLPDAQFKKDDLTRNVSS 908
Query: 1151 GSEVQQSSLTPAQ-YEQNAPKKLPKSNGAITYIDENEILTKDILNDE--VRKLNMTVLDL 1207
E ++ + Q ++ +K+ + E + + +++ E + LN ++ +
Sbjct: 909 KEEEKKKAEMEVQMMKKELDQKIFHRKSLFKKVQEGGLCERQLMDKENNIATLNASLEEN 968
Query: 1208 QRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRL---HWIKRLESTIAKMANE-KADMT 1263
Q+R K + E ++ ++E + ++D + R+ + IK L+ T+A + D
Sbjct: 969 QQRQK---RFEEDLRSFDSSHQRESI-LKDQLTRMIIENKIKELKRTLATFDGQINEDRI 1024
Query: 1264 AKVKDLETALSQSKEKVDRYE-EYSSKSQKVDKPRPNGEDPVALKE 1308
+ K L + E + ++ Q+ +K + E ++ KE
Sbjct: 1025 TEQKQAYNKLQNELRLIGNEEVKIYTQMQEYEKQKKIAEAKLSTKE 1070
>Hs4557773 [Z] KOG0161 Myosin class II heavy chain
Length = 1935
Score = 56.2 bits (134), Expect = 3e-07
Identities = 135/733 (18%), Positives = 293/733 (39%), Gaps = 93/733 (12%)
Query: 639 LQKLPPRLRYLELESPSNNFISKPLRANNRVEKLRKD---ELYNGSKQKRRTRGSAP-DS 694
L++L R+ LE E S A +VEKLR D EL S++ G+
Sbjct: 1108 LKELQARIEELEEELESER------TARAKVEKLRSDLSRELEEISERLEEAGGATSVQI 1161
Query: 695 EGSKKPLIERQIEDGNVSEKTPQEPTTSIPGETDVNEKVLEPIEDIEMLPTFISSSNRLE 754
E +KK E Q ++ E T Q T+ + V E E I+ L + E
Sbjct: 1162 EMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQR-VKQKLEKE 1220
Query: 755 PDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQAS-TEIETNEGNSKKG 813
L + S++ + K + + K + E+ + ++A T+ N+ S++
Sbjct: 1221 KSEFKLELDDVTSNMEQIIKAKA--NLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRA 1278
Query: 814 KDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSE 873
K + E L + + + S L L T+ +++L ++ E
Sbjct: 1279 K---------------LQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL---E 1320
Query: 874 MKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKTES 933
++ + + H L+ + + ++ + +E + E + S ++ A+ K +T++
Sbjct: 1321 EEVKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKANSEVAQWRTKYETDA 1379
Query: 934 INNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQL 993
I R + L A KL ++++ +EA+N + L + K E+E+ + +
Sbjct: 1380 IQ----RTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS-LEKTKHRLQNEIEDLMVDVER 1434
Query: 994 RDT----LEGERAHFESQLALEKQKVSNLKAALLSRHG------------KNDINEEVKP 1037
+ L+ ++ +F+ LA KQK ++ L S KN E ++
Sbjct: 1435 SNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEH 1494
Query: 1038 AAPL--DGKKLEE----LQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNEL 1091
+ K L+E L +L S+ K L+ E ++ L E +
Sbjct: 1495 LETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHE 1554
Query: 1092 NSKVALASKQCAQLRST------------NAHLRNKLQSLEDVVSKISSNTKSKLKPSSY 1139
K+ A + Q+++ RN L+ ++ + + + + T+S+
Sbjct: 1555 EGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSR-----N 1609
Query: 1140 DSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDIL--NDEV 1197
++ ++ + G + L+ A +K KS ++ + + +I D + ND++
Sbjct: 1610 EALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL--LKDTQIQLDDAVRANDDL 1667
Query: 1198 RKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEK----EKLSIRDVVDRLHWIKRLESTIA 1253
++ N+ +++ + + L+ + L E+ KL+ +++++ ++ L S
Sbjct: 1668 KE-NIAIVERRNNL-----LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1721
Query: 1254 KMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNGEDPVALKETIVRL 1313
+ N+K M A + L+T + ++ ++ EE + K+ + E+ ++T L
Sbjct: 1722 SLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA--ITDAAMMAEELKKEQDTSAHL 1779
Query: 1314 LKERKKLTAILKN 1326
+ +K + +K+
Sbjct: 1780 ERMKKNMEQTIKD 1792
>7294543 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting protein
Hip1
Length = 1087
Score = 56.2 bits (134), Expect = 3e-07
Identities = 107/472 (22%), Positives = 204/472 (42%), Gaps = 67/472 (14%)
Query: 854 EDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKG 913
E+ KT +I L +I + + KIA L + ++++EK +++ ++ K +QELD +
Sbjct: 433 EEKEKTNLI--LQKQIEEHKEKIAHLEAVKNEMKEKFDDV--VKQKEIQELDIISTSENL 488
Query: 914 SFSAGTAKEAEVNNKDKTESINNEQAR--------EKSLTAAHGK---LISKVEKDLVEI 962
+ +E N D E ++N +++ EK L A + L++++E+ VE
Sbjct: 489 RLNCLKVEELNGNLNDTLEKLSNAESQINAKTEDIEKMLKAFEAEKALLLTQIEQQSVES 548
Query: 963 EALNKNVTERLFEI-KRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSN---- 1017
++ ++ +L EI ++ ++ E + + QL ESQ++L+ ++ N
Sbjct: 549 KSHSEAQNAQLQEIMDNLEQKDKEFNEVKLQLSSA--------ESQISLKALEIQNNLKA 600
Query: 1018 ---LKAALLSRHGKNDI----NEEVKPA-APLDGKKLEELQAELSSTR--LYARAQHNAA 1067
K+ LL++ + I N E + A L LE+ ++ L T+ + Q NA+
Sbjct: 601 FEAEKSVLLTKIEQLGIEHKNNSEAQNAQLQLTLNNLEQNESALQQTQEIVNQLRQENAS 660
Query: 1068 -----KHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRS---------TNAHLR 1113
+ LQ++ S L++ + + + S + S ++LR N+ L
Sbjct: 661 AGQRNEDLQSKLSLTEVKLTQATQQIDAVTSSYQICSTDLSELRKLVIKTVKEICNSKLS 720
Query: 1114 NKLQSLEDVVSKISSNTKSKL-KPSSYDSQNTQRSISGGSEVQQSSLTPAQ-YEQNAPKK 1171
Q D V I ++ L K ++ + N S G V + Y+Q
Sbjct: 721 GSEQQPLDAVPNIIREMETILNKFNNASAINYVASTEGLQNVMYLGYVFIKLYDQ--CDV 778
Query: 1172 LPKSNGAI----TYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVF 1227
+ K+ AI + +L DI LN + +R+ KT+T ++T + +
Sbjct: 779 IYKTTTAIETGQEIFSKTNLLCTDICQLFQYLLNNETKEPERQ-KTITDIQTKLRDIEKL 837
Query: 1228 CEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEK 1279
EK K S +D K LE + +M D +K+ DL L++++EK
Sbjct: 838 IEKIKASFEQKID---LDKLLEIELREMDAAIDDAASKITDL---LAKAREK 883
>SPBC3D6.04c [D] KOG4593 Mitotic checkpoint protein MAD1
Length = 689
Score = 55.8 bits (133), Expect = 4e-07
Identities = 117/576 (20%), Positives = 238/576 (41%), Gaps = 109/576 (18%)
Query: 727 TDVNEKVLEPIEDIEMLPTFISSSNRLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPA 786
T + + +P + LP F+++S + +P+ K+PS+ + N+
Sbjct: 12 TSMADSPRDPFQSRSQLPRFLATSVK-KPNL----------------KKPSVNSANETK- 53
Query: 787 SFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDT 846
P A ++E + + K+ EL F+ E+ E + +E+ + +
Sbjct: 54 ------NPKLASLEFQLENLKNDLKR--KELEFEREQIELQRKLAEEHEQKNSLQLRLTL 105
Query: 847 CSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGIN-HQLREKLEELEKIQAKLVQELD 905
L + + + I+ + +E +++KI L+ ++ E ++EK L ++
Sbjct: 106 VEKQLEEQSTSYQKEIEEVRNEKEATQVKIHELLDAKWKEIAELKTQIEKNDQALSEKNH 165
Query: 906 TVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEAL 965
V++ ++ A K+ + N +K + + EQ K K ++ E+ L E+
Sbjct: 166 EVMVSNQ----ALQMKDTNLTNLEKLFADSREQLETKC------KELAAAEQQLQELSVH 215
Query: 966 NKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLAL-EKQKVSNLKAALLS 1024
N+ + E IKQ+ ++E E+ + E +L + E +K+ + +
Sbjct: 216 NQQLEES-----------------IKQVSSSIELEKINAEQRLQISELEKLKAAQEERIE 258
Query: 1025 RHGKNDINEEV--KPAAPLDGK--KLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNL 1080
+ N+ N E+ + L+ K + EE + ++++ L + +QTE +++++L
Sbjct: 259 KLSSNNRNVEILKEEKNDLESKLYRFEEYRDKVATLEL-------ENEKIQTELNSWKSL 311
Query: 1081 LSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSN----------- 1129
++ NEL + A+++K L++TNA+L ++ SLE +S +N
Sbjct: 312 IT------NELPTPEAVSNK-LVFLQNTNANLGERVSSLESQLSNKPANQPLGANEKDAA 364
Query: 1130 ----TKSKLKPSSYDSQNTQRSIS-GGSEVQQSSLTPAQYEQNAP---------KKLPKS 1175
++KLK ++ QR S E+ Y+ KKL +
Sbjct: 365 HITELETKLKELHEQNRRLQRQKSLATQEIDLLRENLKSYDDEEAILSEKNTDMKKLERI 424
Query: 1176 NGAITYIDENEI--------LTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVF 1227
G + +DE ++ L D +DEV + + +T+L L +F
Sbjct: 425 EGLVKLVDEYKLKLESMPVSLDVDETSDEVSLQKRRRKNEHKDAGYVTELYRKNQHL-LF 483
Query: 1228 CEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMT 1263
KEK +I + I LES+IA + E A +T
Sbjct: 484 QVKEKTNIEAFL--REQIITLESSIATLRQELAQVT 517
>SPCC162.08c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1837
Score = 55.5 bits (132), Expect = 6e-07
Identities = 168/904 (18%), Positives = 338/904 (36%), Gaps = 112/904 (12%)
Query: 288 KSRISKANSPIQRTTTTTSNIPSEAKELYNMLSSRLKRRNVLFDKKGTINSENNDKTGAS 347
+S I++ I T + + + EL L +R+ L K N + +
Sbjct: 884 QSNITELKQDITLQRTVRNQLEIQTTELKERLKFMEERQENLQSKLIAANKDTTQNPD-N 942
Query: 348 VKVESSHVEIIGSKRDHTHTSFMELPSMQATIADLAKTTSLVKENSAQIEVDRNLIGPER 407
V+VE+ +E+ +K + + +E ++Q KT ++ E Q ++L+ E
Sbjct: 943 VEVEAISIELERTK-EKLRMAELEKSNIQQKYLASEKTLEMMNETHEQF---KHLVESEI 998
Query: 408 SRKNEK------EFQDLETRTS--SPAKESLASPSADTPERKVPQLDLTSPSFDSTPGVT 459
S + EK E DL R KES + A E V + D +
Sbjct: 999 STREEKITSLRSELLDLNKRVEVLKEEKESSSKELAKQLEDAVREKDSALSFKKDYEKIR 1058
Query: 460 EKMDLKEVPSPEYPSSAGQAVQQSESSQISHVIQQAEGADSGSHHGIQVESSELNIPTIF 519
D E +++ S+ S ++ + G + ++ E E+N +
Sbjct: 1059 SDADRVITSLKEDIEKERSLMKECHSNYESEIV--SHGRTTQKLRDLRTEFDEVNTKYLK 1116
Query: 520 EKKDNPQAASA-SGTFH--HVDEKQSTEETAKL----LALXXXXXXXXXXXXXXXHYVGD 572
K + Q S SG ++ K +E + L L L +
Sbjct: 1117 LKANFEQQHSGLSGAEKDWNIQRKAMEDEISSLKDYILGLENQNKLLHSQFDSLSQQITV 1176
Query: 573 FQLLNTMKARMVGPKVAKWKAFNKSKFKDLMKYLIAEHTPLAARSDVSCSNDICNIRNYE 632
Q ++ + A +A + ++L+ YL E + + +++ ++ + +
Sbjct: 1177 LQQNSSENLNIS----ANLEAVQDNDLRELVSYLRHEKEIMDNKYELTILDNRGLNQQVK 1232
Query: 633 SVEVHHLQKLPPRLRYLELESPSNNFISKPLRANNRVEKLRKDELYNGSKQKRRTRGSAP 692
S++ + L L L+ SN+ P+ + ++ +L LY + R+
Sbjct: 1233 SLQ-STVDSLQLELNRLQSLPVSNDQTDTPIISGSQEVQL----LYESNSVLRKDN---- 1283
Query: 693 DSEGSKKPLIERQIEDGNVSEKTPQEPTTSIPGETDVNEKVLEPIEDIEM-----LPTFI 747
D++ K +E+++E N S Q + E L +++ + +
Sbjct: 1284 DAKLGKIQELEKEVEKLNASLNPLQTEINELKAEIGAKTASLNLMKEYNSRWKLRFQSVL 1343
Query: 748 SSSNRLEPDA-----NTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQASTE 802
+ R++P A + K Q + + F N L + E
Sbjct: 1344 NKYERVDPTQLEELKKNCEALEKEKQELETKLQETAKETDTFKQQV-NSLNEEVENLKKE 1402
Query: 803 IETNEGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVI 862
+E + N+K + ++ EKCE++ ++S+++ L N+ NK
Sbjct: 1403 VE--QANTKNTRLAAAWN-EKCENLK---------KSSLTRFAHLKQELTNK--NKELTS 1448
Query: 863 QNLTSEIIQSEMKIASLVGINHQLREKL-EELEKIQAKLVQELDTVLLESKGSFSAGTAK 921
+N +E +Q E I SL NHQL+E + E+I + ++L +
Sbjct: 1449 KNAENEAMQKE--IESLKDSNHQLQESASSDAEQITKEQFEQLKS--------------- 1491
Query: 922 EAEVNNKDKTESINNEQAREKSLTAAHGKL-ISKVEKDLVEI----EALNKNVTERLFEI 976
E E K+ +S N + + A GK IS +EK++ E+ E L + V E+
Sbjct: 1492 EKERTEKELADSKNELEHLQSEAVDADGKTEISNLEKEIHELRSDKEGLVQQVQNLSAEL 1551
Query: 977 KRIKDR-----EVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDI 1031
+++ +EN I +LR LE + ++E + ++ ++ ++ L++ K
Sbjct: 1552 AALREHSPTQGSLENADEIARLRSQLESTKQYYEKE---KETEILAARSELVAE--KEKT 1606
Query: 1032 NEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNEL 1091
EE++ ++++EL+ + AQ N++++ E+K K N
Sbjct: 1607 KEELENQLNEKSQRIKELEEQ---------AQKNSSENTHDNIDDMIKQQVEEKLKENSA 1657
Query: 1092 NSKVAL----------ASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDS 1141
N V L + + + L+NK+ LE+ + ++ + K S
Sbjct: 1658 NFDVKLKKVVAETEFRSKAKISVYEKKTRDLQNKITQLEETIENLNKQLSNPEKTDESTS 1717
Query: 1142 QNTQ 1145
T+
Sbjct: 1718 SVTE 1721
Score = 52.4 bits (124), Expect = 5e-06
Identities = 97/497 (19%), Positives = 198/497 (39%), Gaps = 84/497 (16%)
Query: 869 IIQSEMKIASLVGINHQLRE-------KLEELEKIQAKL---VQELDTVLLESKGSFSAG 918
II ++ L N LR+ K++ELEK KL + L T + E K A
Sbjct: 1262 IISGSQEVQLLYESNSVLRKDNDAKLGKIQELEKEVEKLNASLNPLQTEINELKAEIGAK 1321
Query: 919 TAK---EAEVNNK---------DKTESINNEQARE-----KSLTAAHGKLISKVEKDLVE 961
TA E N++ +K E ++ Q E ++L +L +K+++ E
Sbjct: 1322 TASLNLMKEYNSRWKLRFQSVLNKYERVDPTQLEELKKNCEALEKEKQELETKLQETAKE 1381
Query: 962 IEALNKNVTERLFEIKRIKDREVE-----NHPIIKQLRDTLEGERAHFESQLALEKQKVS 1016
+ + V E++ +K +EVE N + + E + ++ A KQ+++
Sbjct: 1382 TDTFKQQVNSLNEEVENLK-KEVEQANTKNTRLAAAWNEKCENLKKSSLTRFAHLKQELT 1440
Query: 1017 NLKAALLSRHGKN-----------DINEEVKPAAPLDGKKL-----EELQAELSSTRLYA 1060
N L S++ +N D N +++ +A D +++ E+L++E T
Sbjct: 1441 NKNKELTSKNAENEAMQKEIESLKDSNHQLQESASSDAEQITKEQFEQLKSEKERTEKEL 1500
Query: 1061 RAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLE 1120
N +HLQ+E ++++ K+ +LRS L ++Q+L
Sbjct: 1501 ADSKNELEHLQSEAVDADG------------KTEISNLEKEIHELRSDKEGLVQQVQNLS 1548
Query: 1121 DVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEV----QQSSLTPAQYEQNAPKKLPKSN 1176
++ + ++ TQ S+ E+ Q T YE+ ++ +
Sbjct: 1549 AELAALREHSP------------TQGSLENADEIARLRSQLESTKQYYEKEKETEILAAR 1596
Query: 1177 GAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLET--NVGPLSVFCEKEKLS 1234
+ E TK+ L +++ + + + +L+ + + + T N+ + +EKL
Sbjct: 1597 SELVAEKEK---TKEELENQLNEKSQRIKELEEQAQKNSSENTHDNIDDMIKQQVEEKLK 1653
Query: 1235 IRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVD 1294
+ K + T + + + K +DL+ ++Q +E ++ + S +K D
Sbjct: 1654 ENSANFDVKLKKVVAETEFRSKAKISVYEKKTRDLQNKITQLEETIENLNKQLSNPEKTD 1713
Query: 1295 KPRPNGED--PVALKET 1309
+ + + PV K T
Sbjct: 1714 ESTSSVTETKPVTSKPT 1730
>SPAC29E6.03C [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1044
Score = 55.5 bits (132), Expect = 6e-07
Identities = 105/463 (22%), Positives = 203/463 (43%), Gaps = 46/463 (9%)
Query: 852 VNEDLNKTEVIQNLTSEIIQSEM--KIASLVGINHQLREKLEELEKIQAK-LVQELDTVL 908
+ ++K++V +TS + + ++ L +N L +K+Q K L +E+D
Sbjct: 560 IESPVSKSDVYNAITSAVKRDVFINRLQRLRRMNLYEITFLSMKQKMQLKSLREEIDNTK 619
Query: 909 LESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEK--DL-VEIEAL 965
S + +E ++N KT N E+ + + H +L+ +K DL +E++
Sbjct: 620 EALDLSVKERSIQEEKLNESLKTSKTNLEEQTQLA-EKYHEELLDNQQKLYDLRIELDYT 678
Query: 966 NKNVTERLFEIK--------RIKDREVENHPIIKQLRDTLEGERAHFESQ-----LALEK 1012
N + E++ IKD E+ + KQL D ++ + S+ LEK
Sbjct: 679 KSNCKQMEEEMQVLREGHESEIKDFIEEHSKLTKQL-DDIKNQFGIISSKNRDLLSELEK 737
Query: 1013 QK-VSNLKAALLSRHGK--NDIN---EEV-KPAAPLDGKKLEELQAELSSTRLYARAQHN 1065
K ++N AAL S++ K ND+N E++ K A + K +AELS +A ++
Sbjct: 738 SKSLNNSLAALESKNKKLENDLNLLTEKLNKKNADTESFKNTIREAELSK-----KALND 792
Query: 1066 AAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSK 1125
+ + S +N LSE+ + EL S++ Q L + ++L S+E
Sbjct: 793 NLGNKENIISDLKNKLSEESTRLQELQSQLNQDKNQIETLNERISAAADELSSME----S 848
Query: 1126 ISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDEN 1185
I+ N ++LK + N Q I+ G+++ + + + K+ ++
Sbjct: 849 INKNQANELKLAKQKCSNLQEKINFGNKLAKEHTEKISSLEKDLEAATKTASTLS----K 904
Query: 1186 EILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRD-VVDRLHW 1244
E+ T ND ++ ++ D Q + K++ + ++ EKL+ RD ++RL
Sbjct: 905 ELKTVKSENDSLKSVSN---DDQNKEKSVNNEKFKEVSQALAEANEKLNARDEEIERLKV 961
Query: 1245 -IKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEEY 1286
I L++ M + K + DLE+ + ++K+ +EY
Sbjct: 962 DIIGLQNASLNMQSLKDSDNRTISDLESKNKELEKKLKEADEY 1004
>YLR086w [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1418
Score = 55.1 bits (131), Expect = 7e-07
Identities = 72/302 (23%), Positives = 133/302 (43%), Gaps = 30/302 (9%)
Query: 868 EIIQSEMKIAS-LVGINHQLREKLEELEKIQAKL--VQELDTVLLESKGSFSAGTAKEAE 924
+++QS K+AS L I+ ++ +E K Q L V E+ E K S+ ++KE
Sbjct: 399 KLLQSNSKLASTLEKISSSNKDLEDEKMKFQESLKKVDEIKAQRKEIKDRISSCSSKE-- 456
Query: 925 VNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREV 984
K + SL L+SK+EK +++ +++E ++ ++ ++
Sbjct: 457 ---KTLVLERRELEGTRVSLEERTKNLVSKMEKAEKTLKSTKHSISEAENMLEELRGQQT 513
Query: 985 ENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGK 1044
E+ IK L LE ER+ + K K N+ A ++ RH K E++P +
Sbjct: 514 EHETEIKDLTQLLEKERSILDDIKLSLKDKTKNISAEII-RHEK-----ELEPWDLQLQE 567
Query: 1045 KLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQ 1104
K ++Q S L Q K+++T +L++K HK EL + K+
Sbjct: 568 KESQIQLAESELSLLEETQAKLKKNVET---LEEKILAKKTHK-QELQDLILDLKKKLNS 623
Query: 1105 LRS---------TNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQ 1155
L+ T+AHL KL+ ++ V++ + + S +QN + ++ S +Q
Sbjct: 624 LKDERSQGEKNFTSAHL--KLKEMQKVLN-AHRQRAMEARSSLSKAQNKSKVLTALSRLQ 680
Query: 1156 QS 1157
+S
Sbjct: 681 KS 682
>Hs22045440 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 636
Score = 55.1 bits (131), Expect = 7e-07
Identities = 92/435 (21%), Positives = 179/435 (41%), Gaps = 62/435 (14%)
Query: 891 EELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHG- 949
+ + +QA +D L SK +E E K TES + EQ E++
Sbjct: 76 QSTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQEL 135
Query: 950 ----KLISKVEKDLVEIEALNKNVTERLFEI-KRIKDREVENHPIIKQLRDTLEGERAHF 1004
+ I EK + ++ +++ + L + +R+K++ K+L+D AH
Sbjct: 136 DDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQS-------KELKD------AHC 182
Query: 1005 ESQLALEK-----QKVSNL--KAALLSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTR 1057
+ +LA+++ ++++ L + L+RH + D EEV L +K+E L+ EL T
Sbjct: 183 QRKLAMQEFMEINERLTELHTQKQKLARHVR-DKEEEVD----LVMQKVESLRQELRRTE 237
Query: 1058 LYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKV-ALASKQCA------------Q 1104
+ + L E S R L + +H +L +++ L KQ + +
Sbjct: 238 RAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQE 297
Query: 1105 LRSTNAHLRNKLQSLEDVVSK---ISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTP 1161
+ L K E+ +SK I +N LK +DS+ Q +++ + + L
Sbjct: 298 ITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEK 357
Query: 1162 AQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNV 1221
+ E + ++ +S Y E +LT +E +KL L KL T
Sbjct: 358 TRRESQSEREEFESEFKQQYEREKVLLT-----EENKKLT----------SELDKLTTLY 402
Query: 1222 GPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVD 1281
LS+ ++ + ++D+ D+ + E+ I ++ +D L+ S+ E+++
Sbjct: 403 ENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQALASKMTEELE 462
Query: 1282 RYEEYSSKSQKVDKP 1296
S ++ D P
Sbjct: 463 ALRNSSLGTRATDMP 477
>ECU04g1000 [Z] KOG0161 Myosin class II heavy chain
Length = 1700
Score = 55.1 bits (131), Expect = 7e-07
Identities = 116/573 (20%), Positives = 217/573 (37%), Gaps = 83/573 (14%)
Query: 811 KKGKDELHFDPEKCEDVT----QFRKEYLALRASISKD----DTCSSSLVNEDLNKTEVI 862
KK D+L F+ + + + R EY A+ + K+ D+ SL+ + +
Sbjct: 1107 KKLLDDLEFERNRGSKLEKAFQELRGEYEAVEGQLQKERQFRDSTQESLLEKTRGLERRV 1166
Query: 863 QNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKE 922
++L ++ + EM L+ EK E +I +LD + G S +
Sbjct: 1167 KSLNEKLRREEMANRQLMS------EKDEMYREIHVLQQSKLDEIFDREAGFNSIKKNLQ 1220
Query: 923 AEVNNKD-KTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKD 981
E+ + + + ++ + K + A + IS E+ +E K E ++ ++
Sbjct: 1221 MEIQRLEMENQRLSVDLMEAKCMGEASEESISATERFCGMLEEERKKRKEIEYQASEHEN 1280
Query: 982 REVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAP- 1040
R V ++ LR+ +E ER E + +++ KA R D+ E+ A
Sbjct: 1281 RNVILSSEVEMLREMVEMERRSKEEVIRGHEKETGLCKAIAGVRKEVEDLGNEIDMAIEG 1340
Query: 1041 --------LDGKK--LEELQAELSSTRLYARAQHNAAKHLQTECSTYRNL---LSEKKH- 1086
LDG K L+E + ++ S + L E + + +S K H
Sbjct: 1341 FNGMYLNVLDGYKRDLKECKEQVMSKEQVIEELNGRIVRLGREVEERKEIEEEMSRKVHG 1400
Query: 1087 ---KYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQN 1143
+YN + + +L S +C+ L T + +++ + S+ + + + +N
Sbjct: 1401 LMKQYNGVMNDFSLLSTKCSSLERTVSEKEEEIKGYSERCSEYDKRFEGLVCRVDEEIEN 1460
Query: 1144 TQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDEN-----EILTKDILNDEVR 1198
+RS E ++ + + N S I +DE E + +L+ E R
Sbjct: 1461 LRRS----DEERRRCVEKLESGLNG------SIAGIRKLDERYKARIEECAQSVLDGERR 1510
Query: 1199 KL------------NMTVLD------LQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVD 1240
KL + L+ L ++K L ++E G L F E E V
Sbjct: 1511 KLKAMEELCEQLSKKLGELEEEHQGLLDEKMKGLLRIEQLEGELCAFRESE-------VH 1563
Query: 1241 RLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNG 1300
R I ES I+ + T ++ +LS + V + K Q +D+ R
Sbjct: 1564 RQDMISMYESEISTLKR----CTRFKDEVLGSLSGERNPVVVHVSDKEKCQVLDRKR--- 1616
Query: 1301 EDPVALKETIVRLLKERKKLTAILKNQAESKER 1333
+ ++ + R ER+ L AI K E E+
Sbjct: 1617 ---MTVEHELARANDERQSLMAINKKLREEVEK 1646
>CE07978 [Z] KOG4280 Kinesin-like protein
Length = 932
Score = 55.1 bits (131), Expect = 7e-07
Identities = 102/500 (20%), Positives = 201/500 (39%), Gaps = 73/500 (14%)
Query: 883 NHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREK 942
N L+ ++E EK +L +E + + + A + + ++ S + +
Sbjct: 445 NQTLQLEIEASEKRYQELQKETSALRNRYQENLDATILMQTPSAKERRSSSRPKRRETQY 504
Query: 943 SLTAAHGKLISKVEKD---LVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEG 999
+ A L ++VE +++++ N+ ++ E+ +KD+ E + L+G
Sbjct: 505 RPSPARMALFAEVETSEDAVLDLQCQNEKLS---CELSSLKDKHEEATSKSIETERLLQG 561
Query: 1000 ERAHFESQLAL----------------EKQKVSNLKAALLSRHGKNDINEEVKPAAPLDG 1043
E + ++++ EK +NL L H D + + L
Sbjct: 562 EIVALQKEVSIVSESLRKSEAVAEGYKEKVTANNLTLDKLLLH--IDASRKRIAELELSS 619
Query: 1044 KKLEELQAE-LSSTRLYARAQ-HNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQ 1101
K+ E +E L RLY + + + E + R L++K N L +V
Sbjct: 620 KESENRSSEELEEQRLYYVSMIEDLERKASDEYAALREELNQKTLSSNLLQVQVDELQLS 679
Query: 1102 CAQLRSTNAHLRNK---LQSLEDVVSKIS-----------------SNTKSKLKPSSYDS 1141
A ++ NA L K ++SLED + K S S+TK +L+ S ++
Sbjct: 680 NATIKKLNADLSTKAGLIRSLEDSIEKKSQMITRLEEQAVLDSSELSSTKRQLEHSRLEA 739
Query: 1142 QNTQRSISGGSEVQQSSLTPAQYEQNA---PKKLP------KSNGAITYIDENEILTKDI 1192
++ + Q+ L Q + + KKL + A + E+E + K +
Sbjct: 740 IQWRKISEETTSAMQTQLKDHQKDIDQCRHKKKLEIQSMQLSLDNANARVKESEAMMKKL 799
Query: 1193 LNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTI 1252
NDE +K +M + +++ K LSV +K++ +I R + + +
Sbjct: 800 QNDEKQKFDMKMSEIENTFKE---------KLSVSLKKQEDTI-----RRQSLAENQGKL 845
Query: 1253 AKMANEKADMTAKVKDLETALSQSKEKVDR-YEEYSSKSQKVDKPRPNGEDPVALKETIV 1311
M N+ ++ ++ L++ SQ E ++ + VDK R + AL+ETI
Sbjct: 846 EVMENKNRVLSETIESLQSQHSQDTEVINAGLRTRGDRVGYVDKLR---VEKKALEETIS 902
Query: 1312 RLLKERKKLTAILKNQAESK 1331
+L E KL I++ ++ +K
Sbjct: 903 QLRSENDKLKKIMRGESANK 922
>7290766 [K] KOG4673 Transcription factor TMF TATA element modulatory factor
Length = 933
Score = 54.7 bits (130), Expect = 1e-06
Identities = 112/555 (20%), Positives = 226/555 (40%), Gaps = 81/555 (14%)
Query: 775 QPSLTTVNKFPASFENGLQPDNAQASTE-----IETNEGNSKKGKDELHFDPEKCEDVTQ 829
Q ++ K PA + G D + +ST I G+S P+K +++
Sbjct: 221 QLQMSHKGKSPAPAKTGTV-DQSYSSTSSDIEIISNPNGDSSTNSTTTRTSPQKFKELAG 279
Query: 830 FRKEYLALRASISKDDTCSSSLVNED----LNK--------TEVIQNLTSEIIQSEMKIA 877
+ + L+A + SL++ED L+K +VI+ ++QSE + A
Sbjct: 280 GK---VCLKAKGHHREPSEISLLSEDSQSELDKLVQRISELNQVIEAREQRLLQSERQNA 336
Query: 878 SLVGINHQLREKLEELEKI-----QAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKTE 932
L+ N +LR ++E A VQ L LE K S + K +
Sbjct: 337 ELLERNQELRARVEAAANSANSPDAADAVQRLSA--LEKKFQASIRERDALRIQMKSLRD 394
Query: 933 SINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQ 992
+ N+ R++ A ++I+ ++ E E L+K + ++ IK+++ +E + ++K+
Sbjct: 395 ELQNKIPRDE--LAECNEMIAALQS---EGEKLSKEILQQSTIIKKLRAKEKTSDTLLKK 449
Query: 993 LRDTL-----EGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGKKLE 1047
+ + E ER S A E+ + + ++A K ++EE + ++E
Sbjct: 450 NGEQISLLSSESERLK-RSLAAKEEMERTQIEAVCRMTAEKKRVDEENAESR----SRIE 504
Query: 1048 ELQAELSSTRL-YARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCA--- 1103
+LQ+ L++ + + + + K + E + R E + ++L K+ LA A
Sbjct: 505 DLQSRLAALQASFDGLKGDLQKRTRLEQDSLRAEHQEYVQQVSDLREKLRLAEHSLARRE 564
Query: 1104 -QLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTPA 1162
Q+R N L +L++ E + + P ++ QR++ Q S
Sbjct: 565 QQMREENRQLMRRLEAAELRAESSTQELGATTTPLIRQIESLQRTL------DQRSAAWN 618
Query: 1163 QYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVG 1222
+ EQ +KL S + + + E + E ++L T L LE +
Sbjct: 619 REEQQLLQKLDDSQVQLRSLQQLE-----SVQGEKQELLRTRCGL---------LEEKLS 664
Query: 1223 PLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVDR 1282
+ E K+++R LE+ AN++ D ++ L+ + Q +E++
Sbjct: 665 SALMEAEAAKMALRQ--------HDLEA-----ANKENDHKKQLSLLQEEIQQQQERIAS 711
Query: 1283 YEEYSSKSQKVDKPR 1297
E+ + ++ ++ R
Sbjct: 712 LEQLCQRQKEEEEQR 726
>CE04618 [Z] KOG0161 Myosin class II heavy chain
Length = 1956
Score = 54.3 bits (129), Expect = 1e-06
Identities = 86/424 (20%), Positives = 177/424 (41%), Gaps = 64/424 (15%)
Query: 882 INHQLREKLE---ELEKIQAKLV---QELDTVLLESKGSFSAGTAKEAEVNNKDKTESIN 935
I QL+++ E EL+ I+ +L QEL+ ++ + + S ++ E NN ++ + +
Sbjct: 884 IQEQLQQESENSAELDDIRGRLQTRNQELEYIVNDMRDRLSE-EEQQNEKNNDERRKQME 942
Query: 936 NEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIKQLRD 995
+ E+ L + K+ D ++ +N+ ERL E++ D+ ++K+ R
Sbjct: 943 TVRDLEEQLEQEE-QARQKLLLDKTNVDQRLRNLEERLVELQDAYDK------LLKEKR- 994
Query: 996 TLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGK---KLEELQAE 1052
L ++KV L LL D E K G+ +L EL+ +
Sbjct: 995 --------------LLEEKVEGLTTQLL------DHEERAKHGVKAKGRLENQLHELEQD 1034
Query: 1053 LSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHL 1112
L+ R Y + L E ++ L+EK K ELN+ QL + L
Sbjct: 1035 LNRERQYKSELEQHKRKLLAELEDSKDHLAEKMGKVEELNN----------QLMKRDEEL 1084
Query: 1113 RNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTPAQY-EQNAPKK 1171
+++L ++ S + ++ D Q T + E ++++ A+ + +
Sbjct: 1085 QHQLTRYDE-----ESANVTLMQKQMRDMQTTIDELREDMETERNARNKAEMTRREVVAQ 1139
Query: 1172 LPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKE 1231
L K G + + + +D+++ + ++N T +R I+ + T G + K
Sbjct: 1140 LEKVKGDVLDKVDEATMLQDLMSRKDEEVNAT----KRAIEQIQ--HTMEGKIEEQKAKF 1193
Query: 1232 KLSIRDVVDRLHWIKRLESTIAKMAN----EKADMTAKVKDLETALSQSKEKVDRYEEYS 1287
+ ++ D++ K+ S + K N E+ADM ++ L+ + + +K +E +
Sbjct: 1194 SRQVEELHDQIEQHKKQRSQLEKQQNQADQERADMAQEIALLQASRADIDKKRKIHEAHL 1253
Query: 1288 SKSQ 1291
+ Q
Sbjct: 1254 MEIQ 1257
>Hs7705348 [Z] KOG0247 Kinesin-like protein
Length = 1780
Score = 53.9 bits (128), Expect = 2e-06
Identities = 108/526 (20%), Positives = 212/526 (39%), Gaps = 89/526 (16%)
Query: 849 SSLVNEDLNKTEVIQNLTSEIIQ-------SEMKIASLVGINHQLREKLEELEKIQAKLV 901
SS + ED K+E ++ +EI +E A L+ I ++L+ + EE ++ ++V
Sbjct: 814 SSAITEDQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLTIENELKNEKEEKAELNKQIV 873
Query: 902 QELDTVLLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVE 961
+ L K + + + +N D + E +KS + I K+ E
Sbjct: 874 HFQQELSLSEKKNLTLSKEVQQIQSNYDIAIA---ELHVQKSKNQEQEEKIMKLSN---E 927
Query: 962 IEALNKNVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAA 1021
IE +++T + +IK + H I +LR TL+ ++SN+
Sbjct: 928 IETATRSITNNVSQIKLM-------HTKIDELR-TLDSV------------SQISNIDLL 967
Query: 1022 LLSRHGKNDINEEVKPAAPLD--------GKKLEELQAELSSTRLYARAQHNAAKHLQTE 1073
L R N E+ P LD K+++E + + + + H++ + + E
Sbjct: 968 NL-RDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRE---NSFHSSIEAIWEE 1023
Query: 1074 CSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSK 1133
C S+K H+ EL ++ + + N L+ K +D + K +
Sbjct: 1024 CKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQ 1083
Query: 1134 LKPSSYDSQNT-----QRSISGG---SEVQQ-------------SSLTPAQYEQNAPKKL 1172
LK + T Q + G SE+ Q + L + E++ KL
Sbjct: 1084 LKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKL 1143
Query: 1173 P----KSNGAITYIDENEILTKDILNDEVRK---LNMTVLDLQRRIKTLTKLETNVGPLS 1225
+ I ++ N ++ L D V+ LN+ L L+ I LT ++ L
Sbjct: 1144 EQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLL 1203
Query: 1226 VFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVK---DLETALSQSKEKVDR 1282
E+E+ + R ++L + L ++ A+ N KAD+ K + DL+ L+ +K+++ +
Sbjct: 1204 QLKEEEEETNRQETEKLK--EELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQ 1261
Query: 1283 YEEYSS-----------KSQKVDKPRPNGEDPVALKETIVRLLKER 1317
++ S K +++K + + +K+ ++ LKE+
Sbjct: 1262 VQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQ 1307
>Hs17978507 [Z] KOG0161 Myosin class II heavy chain
Length = 1581
Score = 53.9 bits (128), Expect = 2e-06
Identities = 108/556 (19%), Positives = 229/556 (40%), Gaps = 101/556 (18%)
Query: 814 KDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSE 873
K L + E +V Q K L R + D+ S + L K Q LT+E+ ++
Sbjct: 928 KKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKK--CQRLTAELQDTK 985
Query: 874 MKIASLVGINHQLREKLEEL-------------EKIQAKLVQELDTVLLESKGSFSAGTA 920
+ + NH+L +K EK+Q + +Q +LL S
Sbjct: 986 LHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ-QL 1044
Query: 921 KEAEVNNKDKTESINNEQAREKSLTAAHGK---LISKVEKDLVEIEALNKNVTERLFEIK 977
+E +++ T+ + + +A + +++ K ++KV+K L ++EA
Sbjct: 1045 EEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEA------------- 1091
Query: 978 RIKDREVENHPIIKQLRDTLEG-ERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVK 1036
++KD+E E + + T++ E+A ++ +E+ + ++ K + SR +EEV+
Sbjct: 1092 KVKDQEEE----LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKE-MESR------DEEVE 1140
Query: 1037 PAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTY------RNLLSEKKHKYNE 1090
A KKL++++ +L + + L+ + +T R+ SEK+ + +
Sbjct: 1141 EARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDL 1200
Query: 1091 LNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISG 1150
+K LA Q HL+N S ++ + K++L+ S + ++
Sbjct: 1201 KRTKALLADAQLML-----DHLKNSAPSKREI-----AQLKNQLEESEFTCAAAVKARKA 1250
Query: 1151 GS--------EVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNM 1202
++ + E+ + + N ++E++ + +N+ ++K
Sbjct: 1251 MEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ----EDMNELMKKHKA 1306
Query: 1203 TVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEK--A 1260
V R + + L+ + + KEK +++ + L ++E M ++ +
Sbjct: 1307 AVAQASRDLAQINDLQAQLEEAN----KEKQELQEKLQALQ--SQVEFLEQSMVDKSLVS 1360
Query: 1261 DMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNGEDPVALKETIVRLLKERKKL 1320
AK+++LET L + +V R E +S+ LKE + +L +ER +
Sbjct: 1361 RQEAKIRELETRLEFERTQVKRLESLASR----------------LKENMEKLTEERDQR 1404
Query: 1321 TAILKNQAESKERDPN 1336
A AE++E++ N
Sbjct: 1405 IA-----AENREKEQN 1415
Score = 52.4 bits (124), Expect = 5e-06
Identities = 110/494 (22%), Positives = 199/494 (40%), Gaps = 73/494 (14%)
Query: 857 NKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFS 916
NK E IQ L S++ ++E + ++LR + LE ++L EL E S
Sbjct: 800 NKDEEIQQLRSKLEKAEKE-------RNELRLNSDRLESRISELTSELTD---ERNTGES 849
Query: 917 AGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEI 976
A +AE + + E K L + L K + +++E+E + + R EI
Sbjct: 850 ASQLLDAETAERLRAEK------EMKELQTQYDAL--KKQMEVMEMEVMEARLI-RAAEI 900
Query: 977 KRIKDRE-------VENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKN 1029
D + ++ ++++ T + + FE +L +E+Q L+ L
Sbjct: 901 NGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD- 959
Query: 1030 DINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYN 1089
+EE + A KK + L AEL T+L+ Q RN EKK +
Sbjct: 960 --SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQ------------VRNHELEKKQRRF 1005
Query: 1090 ELNSKVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQN-TQRSI 1148
+ A Q +L+ R KLQ +D++ + + K +L+ D TQ+ +
Sbjct: 1006 DSELSQAHEEAQREKLQ------REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVV 1059
Query: 1149 SGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYI-DENEIL-----TKDILNDEVRKLNM 1202
S +E+Q S ++ E + K + + D+ E L T +L +L M
Sbjct: 1060 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1119
Query: 1203 TVLDL-QRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKAD 1261
+ + Q K + + V C+K+ +K++E + + +K
Sbjct: 1120 EMERMRQTHSKEMESRDEEVEEARQSCQKK-------------LKQMEVQLEEEYEDKQK 1166
Query: 1262 MTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNGEDPVALKETIVRLLKE---RK 1318
+ + ++LE L+ ++V+R + S K + D R +A + ++ LK K
Sbjct: 1167 VLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKA--LLADAQLMLDHLKNSAPSK 1224
Query: 1319 KLTAILKNQAESKE 1332
+ A LKNQ E E
Sbjct: 1225 REIAQLKNQLEESE 1238
>Hs13124877 [Z] KOG0161 Myosin class II heavy chain
Length = 1266
Score = 53.9 bits (128), Expect = 2e-06
Identities = 90/422 (21%), Positives = 177/422 (41%), Gaps = 59/422 (13%)
Query: 814 KDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSE 873
+++L + E + + R A + + + + + E+ ++ + +Q ++ Q
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 952
Query: 874 MKIASLVGINHQLREKLEELEKI--QAKLVQELDTVL-LESKGSFSAGTAKEAEVNNKDK 930
+ + + R+KL+ LEK+ +AK+ + D +L ++ + + + K E D
Sbjct: 953 LDLEEQLEEEEAARQKLQ-LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011
Query: 931 TESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPII 990
T ++ E+ + K+LT KL +K E + E+E R+K +E ++ +
Sbjct: 1012 TTNLAEEEEKAKNLT----KLKNKHESMISELEV-------------RLK-KEEKSRQEL 1053
Query: 991 KQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGKKLEELQ 1050
++L+ LEG+ + F Q+A + +++ LK L KK EELQ
Sbjct: 1054 EKLKRKLEGDASDFHEQIADLQAQIAELKMQL--------------------AKKEEELQ 1093
Query: 1051 AELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNA 1110
A L+ ++NA K + R L +L+S+ A +K Q R
Sbjct: 1094 AALARLDDEIAQKNNALKKI-------RELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146
Query: 1111 HLRNKLQSLEDVVSKISSNTKSKLKPSS----YDSQNTQRSISGGSEVQQSSLTPAQYEQ 1166
L LED + ++ + + K + + S ++VQ+ AQ +
Sbjct: 1147 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVE 1206
Query: 1167 NAPKKLPKSNGAITYIDEN-EILTKD--ILNDEVRKLNMTVLDLQRRIKTLTKLETNVGP 1223
++L + A +D+N + L K+ L E+R L +++ + K KLE V
Sbjct: 1207 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK---KLEAQVQT 1263
Query: 1224 LS 1225
LS
Sbjct: 1264 LS 1265
Score = 53.1 bits (126), Expect = 3e-06
Identities = 73/324 (22%), Positives = 147/324 (44%), Gaps = 43/324 (13%)
Query: 1034 EVKPAAPLDGKKLEELQA---ELSSTRLYARAQHNAAKHLQ---TECSTYRNLLSEKKHK 1087
+VKP + ++ EE+QA EL T+ + N K L+ ++ + +NLL E+
Sbjct: 840 KVKPLLQVTRQE-EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA 898
Query: 1088 YNELNS-----KVALASKQCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQ 1142
EL + +V LA+K+ +L + +L+ ED ++ + K + +
Sbjct: 899 ETELYAEAEEMRVRLAAKK-QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 957
Query: 1143 NTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDE-NEILTKD--ILNDEVRK 1199
+ + ++Q +T A K+ K I +D+ N L+K+ +L + +
Sbjct: 958 QLEEEEAARQKLQLEKVT-------AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 1200 LNMTVLDLQRRIKTLTKL----ETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKM 1255
L + + + + K LTKL E+ + L V +KE+ S R +++L ++LE +
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS-RQELEKLK--RKLEGDASDF 1067
Query: 1256 ANEKADMTAKVKDLETALSQSKEKVDRY-----EEYSSKSQKVDKPRPNGEDPVALKETI 1310
+ AD+ A++ +L+ L++ +E++ +E + K+ + K R E
Sbjct: 1068 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE--------LEGH 1119
Query: 1311 VRLLKERKKLTAILKNQAESKERD 1334
+ L+E +N+AE ++RD
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRD 1143
>CE07306 [Z] KOG0161 Myosin class II heavy chain
Length = 1974
Score = 53.9 bits (128), Expect = 2e-06
Identities = 117/674 (17%), Positives = 266/674 (39%), Gaps = 95/674 (14%)
Query: 681 SKQKRRTRGSAPDSEGSKKPL--IERQIEDGNVSEKTPQEPTTSIPGETDVNEKVLEPIE 738
+KQK++ D+EG KK + +E I+ ++ S+ E ++V+ +
Sbjct: 947 TKQKKKIE---QDNEGLKKTVSDLETTIKKQESEKQAKDHQIRSLQDEIQSQDEVISKL- 1002
Query: 739 DIEMLPTFISSSNRLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQ 798
+ + + + N + + ++ + +NK A E+ L D +
Sbjct: 1003 ---------NKEKKHQEEVNRKLLEDIQA------EEDKVNHLNKTKAKLESTL--DELE 1045
Query: 799 ASTEIETN-----EGNSKKGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVN 853
+ E E E +K + EL E E++ + + E + I K D SS+ +
Sbjct: 1046 DTLEREKRGRQDCEKQRRKVEGELKIAQELIEELNRHKHEQEQV---IKKKDIELSSIQS 1102
Query: 854 EDLNKTEVIQNLTSEIIQSEMKIASL---VGINHQLREKLEELEKIQAKLVQELDTVLLE 910
++ ++ L +I + +I L + R K E+ ++EL L E
Sbjct: 1103 RLEDEQSLVAKLQRQIKELLARIQELEEELDAERNSRSKAEKARNEMQMELEELGDRLDE 1162
Query: 911 SKGSFSA----GTAKEAEVNN--KDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEA 964
+ G+ A +EAE+ +D ++ N + +L H ++++ L I+
Sbjct: 1163 AGGATQAQIELNKKREAELAKLRQDLEDAAINSETSMAALRKKHNDAVAELSDQLDTIQK 1222
Query: 965 LN------KNVTER-LFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSN 1017
+ KN +R + E+++ D E + +++ LE + + + + +
Sbjct: 1223 MRGKLEREKNDKQREVDELQQSADVEAKQRQNCERMAKQLEAQLTDMTLKSDEQARLIQE 1282
Query: 1018 LKAALLSRHGKN-DINEEVKPAAPL----------DGKKLEELQAELSSTRLYARAQHNA 1066
L H +N D+N +++ A +LEEL+ L ++ H+
Sbjct: 1283 LTMGKNKVHNENQDLNRQLEDAEAQLCALNRIKQQQHSQLEELKRTLDQETRERQSLHSQ 1342
Query: 1067 AKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRST-NAHLRNKLQSLEDVVSK 1125
+ Q EC +R L E++ ++ +++ A+ + Q R+ ++ + LE+ K
Sbjct: 1343 VSNYQLECEQFRESLEEEQDAKTDVQRQLSKANSEIQQWRAKFEGEGVSRAEELEETRRK 1402
Query: 1126 ISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDEN 1185
++ K++ +N + I ++++ A ++A ++N + +++
Sbjct: 1403 LT----HKVQEMQEQLENANQKI---GTLEKNKQRLAHDLEDAQVDADRANSIASSLEKK 1455
Query: 1186 EILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKL------------ 1233
+ +L++ RK V ++++ ++ ET F + +L
Sbjct: 1456 QKGFDKVLDEWRRKCEALVAEVEQ-----SQRETRAAATETFRLRNQLEESGEQTEAVKR 1510
Query: 1234 -------SIRDVVDRL----HWIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVDR 1282
++D+ D+L + L+ ++ EK ++ + + E AL + KV R
Sbjct: 1511 ENKALAQELKDIADQLGEGGKSVHDLQKMRRRLEIEKEELQQALDEAECALEAEEAKVMR 1570
Query: 1283 YE-EYSSKSQKVDK 1295
+ E S +++K
Sbjct: 1571 AQIEVSQIRSEIEK 1584
>7302958 [Z] KOG0240 Kinesin (SMY1 subfamily)
Length = 975
Score = 53.5 bits (127), Expect = 2e-06
Identities = 112/551 (20%), Positives = 212/551 (38%), Gaps = 112/551 (20%)
Query: 848 SSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTV 907
+S VNE + L ++ + +I QL+E++ E E++ A +E +T+
Sbjct: 427 ASVAVNEQARLATECERLYQQLDDKDEEINQQSQYAEQLKEQVMEQEELIANARREYETL 486
Query: 908 LLESKGSFSAGTAKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNK 967
E A+ + N K E QA E+ L + + +++ +I+ALN+
Sbjct: 487 QSEM--------ARIQQENESAKEEVKEVLQALEE-LAVNYDQKSQEIDNKNKDIDALNE 537
Query: 968 NVTERLFEIKRIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHG 1027
+ ++ ++QL+D ++ L + + + A+ G
Sbjct: 538 ELQQKQSVFNAASTE-------LQQLKDMSSHQKKRITEMLTNLLRDLGEVGQAIAP--G 588
Query: 1028 KNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHK 1087
++ I+ ++ A D K+EE + + RL+ AK++ CS ++ K
Sbjct: 589 ESSIDLKMSALAGTDASKVEE---DFTMARLFISKMKTEAKNIAQRCSNMETQQADSNKK 645
Query: 1088 YNELNSKVA----LASKQCAQLRSTNAHLR---NKLQSLEDV----------------VS 1124
+E + L S+ A+++S +R NK ++LE+ VS
Sbjct: 646 ISEYEKDLGEYRLLISQHEARMKSLQESMREAENKKRTLEEQIDSLREECAKLKAAEHVS 705
Query: 1125 KISSNTKSKLKP--SSYDSQNT--------------------QRSISGGSEVQQSSLTP- 1161
+++ K + + S +DSQ Q + +V Q L
Sbjct: 706 AVNAEEKQRAEELRSMFDSQMDELREAHTRQVSELRDEIAAKQHEMDEMKDVHQKLLLAH 765
Query: 1162 ----AQYEQNAPKKLPKSNGAITYI---DENEILTKDI--LNDEVRKLNMT--------V 1204
A YE+ + KS+ I + E KD+ L D V K T V
Sbjct: 766 QQMTADYEKVRQEDAEKSSELQNIILTNERREQARKDLKGLEDTVAKELQTLHNLRKLFV 825
Query: 1205 LDLQRRIKTLTKLETNVGPLSVFCEKEKLS-IRDVVDRLHWIKR--------LESTIAKM 1255
DLQ+RI+ E + +K+K+S + + +D+L + + L + K+
Sbjct: 826 QDLQQRIRKNVVNEESEEDGGSLAQKQKISFLENNLDQLTKVHKQLVRDNADLRCELPKL 885
Query: 1256 ANEKADMTAKVKDLETALSQSKE-----------KVDRYEEYSSKSQ--------KVDKP 1296
+VK LETAL ++KE +VDR +E + ++ KP
Sbjct: 886 EKRLRCTMERVKALETALKEAKEGAMRDRKRYQYEVDRIKEAVRQKHLGRRGPQAQIAKP 945
Query: 1297 RPNGEDPVALK 1307
+G+ +A++
Sbjct: 946 IRSGQGAIAIR 956
>Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1427
Score = 53.1 bits (126), Expect = 3e-06
Identities = 111/509 (21%), Positives = 207/509 (39%), Gaps = 66/509 (12%)
Query: 852 VNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLES 911
VN+ K E L+S++ + +A + + E+ E+L K + KL ++ ++ S
Sbjct: 867 VNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMS 926
Query: 912 KGSFSAGTAKEAEVNNKDK---------TESINNEQAREKSLTAAHGKLISKVEKDLVEI 962
+ S T E+ K++ T++ N +KS+ V+ + +
Sbjct: 927 GDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIED------MTVKAEQSQQ 980
Query: 963 EALNKNVTERLFEIKRIKDREVENHPIIKQLRD-TLEGERAHFESQLALEKQKVSNLKAA 1021
EA K+ E+ +++ D E + Q ++ ERA E++ E + + NL+
Sbjct: 981 EAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHE-EILQNLQKT 1039
Query: 1022 LLSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLL 1081
LL D +++K A + L+EL+ R Q + AK QT + +
Sbjct: 1040 LL------DTEDKLKGAREENSGLLQELEE--------LRKQADKAKAAQTAEDAMQIME 1085
Query: 1082 SEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSL-EDVVSKISSNTKSK--LKPSS 1138
K K L S + TNA L+N+L +L E+ + + KSK L +
Sbjct: 1086 QMTKEKTETLAS--------LEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVEN 1137
Query: 1139 YDSQNTQRSIS--GGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDE 1196
+ ++ I + Q+S A E+N KL + G +E+ + L +E
Sbjct: 1138 QKMEEFRKEIETLKQAAAQKSQQLSALQEENV--KLAEELGR----SRDEVTSHQKLEEE 1191
Query: 1197 VRKLNMTVLDLQRRIKTLTK--------LETNVGPLSVF-----CEKEKLSIRDVVDRLH 1243
LN +L++++R K L+ ++ S E EKL V R
Sbjct: 1192 RSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGE 1251
Query: 1244 --WIKRLESTIAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKVDKPRPNGE 1301
K L S + + ++K + KVK+LE L ++K ++ ++ +Q + R
Sbjct: 1252 NASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSS-SSGNTDTQADEDERAQES 1310
Query: 1302 DPVALKETIVRLLKERKKLTAILKNQAES 1330
L IV L ++ + L ++ +E+
Sbjct: 1311 QIDFLNSVIVDLQRKNQDLKMKVEMMSEA 1339
Score = 52.0 bits (123), Expect = 6e-06
Identities = 83/386 (21%), Positives = 156/386 (39%), Gaps = 44/386 (11%)
Query: 623 NDICNIRNYESVEVHHLQKLPPRLRYLELESPSNNFISKPLRANNRVEKLRKDELYNGSK 682
NDI I L K+ LR E + K +AN L+K K
Sbjct: 917 NDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQL--KLTKANENASFLQKSIEDMTVK 974
Query: 683 QKRRTRGSAPDSEGSKKPLIERQIEDGNVSEKTPQEPTTSIPGETD--------VNEKVL 734
++ + +A E KK L ER++ D +T + + +E++L
Sbjct: 975 AEQSQQEAAKKHEEEKKEL-ERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL 1033
Query: 735 EPIEDIEMLPT-------------FISSSNRLEPDANTLSAHALPSSVIGVKKQPSLTTV 781
+ ++ +L T + L A+ A + + +Q +
Sbjct: 1034 QNLQKT-LLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKT 1092
Query: 782 NKFPASFENGLQPDNAQASTEIETNEGNSKKGKDELHFDPE----KCEDVTQFRKEYLAL 837
AS E+ Q NA+ E++T + N+ K +EL+ E + + + +FRKE L
Sbjct: 1093 ETL-ASLEDTKQT-NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETL 1150
Query: 838 RASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQ 897
+ + ++ S+L E++ E + E+ + +N+QL E++K +
Sbjct: 1151 KQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLL----EMKKRE 1206
Query: 898 AKLVQELDTVLLESKGSFSAGTA----KEAEVNN-KDKTESINNEQAREKSLTAAHGKLI 952
+K +++ D + S S +A K+AE+ +++ + E A KSL + ++
Sbjct: 1207 SKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHS----VV 1262
Query: 953 SKVEKDLVEIEALNKNVTERLFEIKR 978
+E D V++E KN+ +L E KR
Sbjct: 1263 QTLESDKVKLELKVKNLELQLKENKR 1288
>Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription factor interacts
with stathmin
Length = 1591
Score = 52.0 bits (123), Expect = 6e-06
Identities = 108/500 (21%), Positives = 210/500 (41%), Gaps = 64/500 (12%)
Query: 860 EVIQNLTSEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGT 919
EV+QN +E + + +++ + ++ +KL E+E I Q + L+
Sbjct: 904 EVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHS--QNCEIKELKQSREIVLED 961
Query: 920 AKEAEVNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRI 979
K+ V N +K + + +A +SL +H K + + I+ K +T+ ++ +
Sbjct: 962 LKKLHVENDEKLQLL---RAELQSLEQSHLKELEDT-LQVRHIQEFEKVMTDHRVSLEEL 1017
Query: 980 KDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAA 1039
K EN II Q++++ E QL K KVS+L K ++ +K A
Sbjct: 1018 KK---ENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLS----DTRCKLEVELALKEAE 1070
Query: 1040 PLDGK-KLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYN----ELNSK 1094
+ K LEE +A+ T Q ++L+TE S + + Y EL +
Sbjct: 1071 TDEIKILLEESRAQQKETLKSLLEQE--TENLRTEISKLNQKIQDNNENYQVGLAELRTL 1128
Query: 1095 VALASKQC-AQLRSTNAHLRNKLQSLEDVVSKISSNT---KSKLKPSSYDSQNTQRSISG 1150
+ + QC ++L S + N L++ + V+ + + + LK + Q+ S
Sbjct: 1129 MTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELS 1188
Query: 1151 GSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRR 1210
E Q+ Q E + E + +++ D + ++ D ++
Sbjct: 1189 ALERQKDEKITQQEE------------------KYEAIIQNLEKDRQKLVSSQEQDREQL 1230
Query: 1211 IKTLTKLETNVGPLSVFCEKEKLSIRDVVDR--LHWIKRLESTIAK---MANEKADMTAK 1265
I+ KL KE R+VV++ L +K LE+ IAK + + + D ++
Sbjct: 1231 IQ---KLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSL 1287
Query: 1266 VKDLETALSQSKEK-VDRYEEYSS-KSQKVDKPRPNGEDPVALKETIVRLLKERKK---- 1319
V +L+ L + K K +++ EE K++++ R + +A ++T + R+K
Sbjct: 1288 VAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTS---LIAEQQTNFNTVLTREKMRKE 1344
Query: 1320 -----LTAILKNQAESKERD 1334
L+ LK+ + +ERD
Sbjct: 1345 NIINDLSDKLKSTMQQQERD 1364
>Hs4505983 [R] KOG0249 LAR-interacting protein and related proteins
Length = 1202
Score = 52.0 bits (123), Expect = 6e-06
Identities = 86/393 (21%), Positives = 152/393 (37%), Gaps = 87/393 (22%)
Query: 693 DSEGSKKPLIERQIEDGNVSEKTPQEP-TTSIPGETDVNEKVLEPIEDIEMLPTFISSSN 751
+ KK L + ++ + E TP S G E + + IE E++ +
Sbjct: 208 EQNNQKKTLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQS 267
Query: 752 RLEPDANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETNEGNSK 811
+++ +LS+H + + L T K E + +T+++ + +
Sbjct: 268 QMKERLASLSSHV-------TELEEDLDTARKDLIKSE--------EMNTKLQRDVREAM 312
Query: 812 KGKDELHFDPEKCEDVTQFRKEYLALRASISKDDTCSSSLVNEDLNKTEVIQNLTSEIIQ 871
K+++ E +T K YLA + + + L NE NK + + Q
Sbjct: 313 AQKEDME------ERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHR-------Q 359
Query: 872 SEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVNNKDKT 931
+E K N QL+E+LE E+ KL Q L A T E E +
Sbjct: 360 TEDK-------NRQLQERLELAEQ---KLQQTLR----------KAETLPEVEAELAQRV 399
Query: 932 ESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDREVENHPIIK 991
+++ + R HG + ++ + ++E N+ E++R + RE N K
Sbjct: 400 AALSKAEER-------HGNIEERLRQMEAQLEEKNQ-------ELQRARQREKMNEEHNK 445
Query: 992 QLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDGKKLEE--- 1048
+L DT++ + +L L +LK + + KN + EV+ A K+LEE
Sbjct: 446 RLSDTVDKLLSESNERLQL------HLKERMAALEDKNSLLREVESAK----KQLEETQH 495
Query: 1049 -----------LQAELSSTRLYARAQHNAAKHL 1070
L+AEL RL + H+ HL
Sbjct: 496 DKDQLVLNIEALRAELDHMRLRGASLHHGRPHL 528
>Hs4505065 [D] KOG4593 Mitotic checkpoint protein MAD1
Length = 803
Score = 52.0 bits (123), Expect = 6e-06
Identities = 83/407 (20%), Positives = 171/407 (41%), Gaps = 53/407 (13%)
Query: 932 ESINNEQAREKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEI--------KRIKDRE 983
+S+ E+ E+ + +H + +VE++ +++E +K L +R DR
Sbjct: 47 QSMQLEERAEQIRSKSH---LIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRN 103
Query: 984 VENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAPLDG 1043
E I+QL++ G + QL +Q NL AA K D + G
Sbjct: 104 QELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQA-------G 156
Query: 1044 KKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCA 1103
+ + L+ +S + Q K L++E + L + K E N K+
Sbjct: 157 ETINALKGRISELQWSVMDQEMRVKRLESEKQDVQEQLDLQHKKCQEANQKI-------Q 209
Query: 1104 QLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLTPAQ 1163
+L+++ + Q ++D+ K+S + + S+ R E++Q
Sbjct: 210 ELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKSE-LVRLPRLERELEQLR----- 263
Query: 1164 YEQNAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQR-----RIKTLTKLE 1218
E++A +++ ++NG + +E E L + + E + + L+L+ ++++ +L+
Sbjct: 264 -EESALREMRETNGLLQ--EELEGLQRKLGRQEKMQETLVGLELENERLLAKLQSWERLD 320
Query: 1219 TNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQSKE 1278
+G LSIR D ++ L+ + ++ + +T+ + LE A Q +E
Sbjct: 321 QTMG----------LSIRTPEDLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQE 370
Query: 1279 KVDRYEEYSSKSQKVDKPRPNGEDPV-ALKETIVRLLKERKKLTAIL 1324
++ + S + + K R E L++ ++ L KER + AIL
Sbjct: 371 EL---RQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAIL 414
>7303314 [S] KOG0992 Uncharacterized conserved protein
Length = 611
Score = 52.0 bits (123), Expect = 6e-06
Identities = 88/404 (21%), Positives = 164/404 (39%), Gaps = 56/404 (13%)
Query: 978 RIKDREVENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLKAALLSR--HGKNDINEEV 1035
R++ R V I D + G + ES+ E + N LS G + EE
Sbjct: 34 RLRSRRVS---INSNSADDVGGGGFYNESEQLCELRSQCNELTTKLSTVTQGLQQLQEEK 90
Query: 1036 KPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHK-------Y 1088
+ LE ++ + +Y Q Q E +NLLS ++ +
Sbjct: 91 TRVDKTNEILLESVRVAQTQKDIYCEEQEKIQNLQQIEIDKLKNLLSFREQESVDRMGLM 150
Query: 1089 NELNSKVALASKQCAQLR---STNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQ 1145
+ ++ S++ +LR S LR++L+ L + + + L ++++ +
Sbjct: 151 RQQTQQIESLSEELERLRPIESVAEDLRDELEQLRHSTQQEKNLLTTTLAAVQEENRHLK 210
Query: 1146 RSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKDI----------LND 1195
+ + E + SL EQ + + +++E + DI L
Sbjct: 211 KRMKIVEESRLESLGKLNSEQQVQALIREHKLLEQHLEEAHLQLSDIKGSWSGQNLALET 270
Query: 1196 EVRKLNMTVLD----LQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLEST 1251
+V +L+ V + ++ +K+ + +S EK K I+ D+ +K LE
Sbjct: 271 QVSRLSKQVAEETTEKRKALKSRDDAIESRKQVSFELEKAKDEIKQRDDK---VKLLEEE 327
Query: 1252 IAKMA------------------NEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKV 1293
I +++ N+ ++ +VKDL+T L+ + DR+ EYSS +++V
Sbjct: 328 IDELSVALKECREENEQQVLFERNKSQNLETEVKDLKTRLTAAD---DRFSEYSSNAEQV 384
Query: 1294 -DKPRPN-GEDPVALKETIVRLLKER-KKLTAILKNQAESKERD 1334
K R E L ETI++L ER +K+TAIL+N ++ D
Sbjct: 385 AQKLRVQVTEKQEQLDETIMQLEIEREEKMTAILRNAEIAQSED 428
>7292323 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 1381
Score = 52.0 bits (123), Expect = 6e-06
Identities = 99/479 (20%), Positives = 204/479 (41%), Gaps = 58/479 (12%)
Query: 867 SEIIQSEMKIASLVGINHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAEVN 926
SE ++ A L N +LR++LEE + +L +ELD + K F + E
Sbjct: 246 SESNHLAVECADLRSKNRKLRQELEEKSENLLELREELD----DKKARFDKLRQESQEWF 301
Query: 927 NKDKTESINNEQA---REKSLTAAHGKLISKVEKDLVEIEALNKNVTERLFEIKRIKDRE 983
+ K S ++ RE++ + ++ VE++ + + + F R+++
Sbjct: 302 TEAKRASAYRDEVDILRERA---------ERADRLEVEVQKYREKLGDSDFYKSRVEELR 352
Query: 984 VENHPII---KQLRDTLEGERAHFESQLALEKQKVSNLKAALLSRHGKNDINEEVKPAAP 1040
+N ++ + L + L+ R E ++LE + + K IN ++
Sbjct: 353 EDNRVLLESKEMLEEQLQRYRKRSEHAISLESEIIKY----------KQKIN-DMALERD 401
Query: 1041 LDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYRNLLSEKKHKYNELNSKVALASK 1100
+D KLEEL E S +L AR N+ L SE + N ++ ++
Sbjct: 402 VDRSKLEELLEENSQLQLVAR-NLNSTMDLDKS-------FSENEDDCNSGDNSLSEQLT 453
Query: 1101 QCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSKLKPSSYDSQNTQRSISGGSEVQQSSLT 1160
AQ R+ L N+ + +LK SS+ ++T + + E ++ SL
Sbjct: 454 NNAQTRALKLELENRRLTA----------ALEQLKESSF-HESTSKMLELEKEKKKLSLK 502
Query: 1161 PAQYEQNAPKKLPKSNGAI-----TYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLT 1215
Q ++N +L + N + ++EN+ L +D +++ + + L+ + + L+
Sbjct: 503 IEQMQENI-NRLTQQNVELEGVFKNALEENKKL-QDAVDNRQKSYDRQSLEREADRQKLS 560
Query: 1216 KLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLESTIAKMANEKADMTAKVKDLETALSQ 1275
E +V L+ ++ + + R ++RL + K + + + + + + L +
Sbjct: 561 DAEQHVETLNKEKQRIQTLNESIQRRADDLERLAESKTKELEQYLEKSRQYELTKQKLYE 620
Query: 1276 SKEKVDRYE-EYSSKSQKVDKPRPNGED-PVALKETIVRLLKERKKLTAILKNQAESKE 1332
+ +V YE E +S ++V K + E V L ++I RL + K+L + K +S++
Sbjct: 621 IEARVSTYERENASLLKEVSKLKEGSEQKSVQLDDSINRLDVQSKELQKLGKALEDSEQ 679
>YKL179c [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 679
Score = 51.6 bits (122), Expect = 8e-06
Identities = 112/544 (20%), Positives = 199/544 (35%), Gaps = 88/544 (16%)
Query: 756 DANTLSAHALPSSVIGVKKQPSLTTVNKFPASFENGLQPDNAQASTEIETNEGNSKKGKD 815
D TLS ++ S KK L K N + Q EI+ SK +
Sbjct: 34 DKETLSLNSRKSLATETKKFKKLEPEEKL-----NNVNKIIKQYQREIDNLTQRSKFSEK 88
Query: 816 ELHFDPEKCEDVTQFRKEYLALRASISKDDTCSS-----SLVNEDLNKTEVIQNLTSEII 870
L EK + + + + K D S + + L K + L S ++
Sbjct: 89 VLFDVYEKLSEAPDPQPLLQSSLEKLGKIDDSKELKEKISYLEDKLAKYADYETLKSRLL 148
Query: 871 QSEMKIASLVG---------INHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAK 921
E A + IN EK ++ +A L+++L V ++K + A +K
Sbjct: 149 DLEQSSAKTLAKRLTAKTQEINSTWEEKGRNWKEREADLLKQLTNVQEQNK-ALEAKISK 207
Query: 922 EAEVNNKDKTESINNEQAREKSLTAAHGKLISK----VEKDLVEIEALNKNVTERLFEIK 977
++ + +E S A L+++ + + ++E N+ ++ L +
Sbjct: 208 NIDIEGNGNEDGDQENNQKEVSTRIAEYNLVTQELETTQARIYQLEKRNEELSGALAKAT 267
Query: 978 RIKDREVENHPIIKQLR-DTLEGERAHFESQLALEKQKVSN----LKAALLS-------- 1024
++E E H K+L+ + LE E A + E++ S+ LK L S
Sbjct: 268 SEAEKETELHA--KELKLNQLESENALLSASYEQERKSTSHAINELKEQLNSVVAESESY 325
Query: 1025 -------RHGKNDINEEVKPAAPLDG-KKLE----------ELQAELSSTRLYARAQHNA 1066
R N+ ++ K L KK+E ++++E + + + +A
Sbjct: 326 KSELETVRRKLNNYSDYNKIKEELSALKKIEFGVNEDDSDNDIRSEDKNDNTFESSLLSA 385
Query: 1067 AKHLQTECSTYRNLLSEKKHKYNELNSKVALASKQCAQLRSTNAHLRNKLQSLEDV---- 1122
K LQ + YR+ + ++ + NEL V +Q A L+ N L L+ +E+V
Sbjct: 386 NKKLQATLAEYRSKSTAQEEERNELKKSVDQLKQQIATLKEANEKLETDLEKVENVSPHF 445
Query: 1123 ---VSKISSNTKSKLKPSSYDSQNTQRSI----SGGSEVQQSSLTPAQYEQ--------- 1166
S +S T+ +S+ T I G QS++ P +Q
Sbjct: 446 NETASMMSGVTRQMNNRTSHKMSPTSSIIGIPEDGELSGNQSTILPIVTKQRDRFRSRNM 505
Query: 1167 NAPKKLPKSNGAITYIDENEILTKDILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSV 1226
+ K+L + N K L E+ KL L RI+ L N P++
Sbjct: 506 DLEKQLRQGNS-----------EKGKLKLEISKLKGDNTKLYERIRYLQSYNNNNAPVNQ 554
Query: 1227 FCEK 1230
E+
Sbjct: 555 STER 558
>CE27954 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 3484
Score = 51.6 bits (122), Expect = 8e-06
Identities = 140/741 (18%), Positives = 283/741 (37%), Gaps = 99/741 (13%)
Query: 664 RANNRVEKLRKDELYNGSKQKRRTRGSAPDSEGSKKPLIE---RQIEDGNVSEKTPQEPT 720
R+ +K RK E +K+ + + + S + LIE +++++ +SE+ P +
Sbjct: 573 RSETPDDKSRKKEGLPPAKKSEK-KDEVTAEKQSTEALIESKKKEVDESKISEQQPSDKN 631
Query: 721 TS----IPGETDVNEKVLEPIEDIEMLPTFISSSNRLEPDANTLS--AHALPSSVIGVKK 774
S +P E + + + +IE +P + + E +++S ++ L + K
Sbjct: 632 KSEVVGVP-EKAAGPETKKDVSEIEEVPKKKTIKKKTEKSDSSISQKSNVLKPADDDKSK 690
Query: 775 QPSLTTVNKFPASFENGLQPDN-----AQASTEIETNEGNSKKGKDE-LHFDPEKCEDVT 828
+T +K + + D+ A + +IET K K + L EK +
Sbjct: 691 SDDVTDKSKKTTEDQTKVATDSKLEKAADTTKQIETETVVDDKSKKKVLKKKTEKSDSFI 750
Query: 829 QFRKEYLALRASISKDDTCSSSL--VNEDLNKTEVIQNLTSE-------IIQSEMKIASL 879
+ E + ++ + + VN+ + EV NL E I ++KI +
Sbjct: 751 SQKSETPPVVEPTKPAESEAQKIAEVNKAKKQKEVDDNLKREAEVAAKKIADEKLKIEAE 810
Query: 880 VGI---------------NHQLREKLEELEKIQAKLVQELDTVLLESKGSFSAGTAKEAE 924
I + QL+ + E + K A EL+ K + + K+ E
Sbjct: 811 ANIKKTAEVEAAKKQKEKDEQLKLETEVVSKKSAAEKLELEKQAQIKKAAEADAVKKQKE 870
Query: 925 VNNKDKTESINNEQAREKSLTAAHGKLISKVEKDLVE-------------IEALNKNVTE 971
+N K+K E+ A + L KV ++ V+ ++ ++ ++
Sbjct: 871 LNEKNKLEAAKKSAADKLKLEEESAAKSKKVSEESVKFGEEKKTKAGEKTVQVESEPTSK 930
Query: 972 RLFEIKRIKDRE-VENHPIIKQLRDTLEGERAHFESQLALEKQKVSNLK----------- 1019
+ + K + E + P K ++ E + + A + +KVS K
Sbjct: 931 KTIDTKDVGATEPADETPKKKIIKKKTEKSDSSISQKSATDSEKVSKQKEQDEPTKPAVS 990
Query: 1020 -AALLSRHGKNDINEEVKPAAPLDGKKLEELQAELSSTRLYARAQHNAAKHLQTECSTYR 1078
+++ K+ +E LD + + + E + + AQ K + + +
Sbjct: 991 ETQMVTEADKSKKQKETDEKLKLDAEIAAKTKQE-ADEKSKLDAQEKIKKVSEDDAARKE 1049
Query: 1079 NLLSEKKHKYNELNSKVALASK----QCAQLRSTNAHLRNKLQSLEDVVSKISSNTKSK- 1133
L++K +E+ +K A A K + AQ + K Q +D K+ + SK
Sbjct: 1050 KELNDKLKLESEIATKKASADKLKLEEQAQAKKAAEVEAAKKQKEKDEQLKLDTEAASKK 1109
Query: 1134 --LKPSSYDSQNTQRSISGGSEVQQSSLTPAQYEQNAPKKLPKSNGAITYIDENEILTKD 1191
+ + Q + +G V++ + + A KK + G + +E+ +K
Sbjct: 1110 AAAEKLELEKQAQIKKAAGADAVKKQKELDEKNKLEANKK--SAAGKLKIEEESAAKSKQ 1167
Query: 1192 ILNDEVRKLNMTVLDLQRRIKTLTKLETNVGPLSVFCEKEKLSIRDVVDRLHWIKRLEST 1251
+ ++ + LD Q + KT K +T + EK++ S ++ + ++ +
Sbjct: 1168 TVEEQAK------LDAQTKAKTAEK-QTKL-------EKDEKSTKESESKETVDEKPKKK 1213
Query: 1252 IAKMANEKADMTAKVKDLETALSQSKEKVDRYEEYSSKSQKV-DKPRPNGEDPVALKETI 1310
+ K EK+D + K SK V+ S++QKV D R E K+ +
Sbjct: 1214 VLKKKTEKSDSSISQKS-----ETSKTVVESAGPSESETQKVADAARKQKETDE--KQKL 1266
Query: 1311 VRLLKERKKLTAILKNQAESK 1331
+ +K K +AESK
Sbjct: 1267 EAEITAKKSADEKSKLEAESK 1287
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.307 0.124 0.327
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,170,113
Number of Sequences: 60738
Number of extensions: 3146070
Number of successful extensions: 14464
Number of sequences better than 1.0e-05: 58
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 14042
Number of HSP's gapped (non-prelim): 289
length of query: 1336
length of database: 30,389,216
effective HSP length: 119
effective length of query: 1217
effective length of database: 23,161,394
effective search space: 28187416498
effective search space used: 28187416498
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)