ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactVI3614 good M KOG1268 Cell wall/membrane/envelope biogenesis Glucosamine 6-phosphate synthetases, contain amidotransferase and phosphosugar isomerase domains
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactVI3614 1259744 1261855 704
(704 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL104c [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 1175 0.0
SPBC12C2.11 [M] KOG1268 Glucosamine 6-phosphate synthetases cont... 835 0.0
Hs4826742 [M] KOG1268 Glucosamine 6-phosphate synthetases contai... 772 0.0
Hs4503981 [M] KOG1268 Glucosamine 6-phosphate synthetases contai... 762 0.0
7289004 [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 745 0.0
7301670 [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 731 0.0
CE27915 [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 713 0.0
CE03255 [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 713 0.0
CE03144 [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 709 0.0
ECU07g1280 [M] KOG1268 Glucosamine 6-phosphate synthetases conta... 687 0.0
At3g24090 [M] KOG1268 Glucosamine 6-phosphate synthetases contai... 658 0.0
YMR085w [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 546 e-155
YMR084w [M] KOG1268 Glucosamine 6-phosphate synthetases contain ... 314 3e-85
Hs19923227 [F] KOG0572 Glutamine phosphoribosylpyrophosphate ami... 67 9e-11
CE01074 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidot... 65 3e-10
7298959 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidot... 62 4e-09
>YKL104c [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 717
Score = 1175 bits (3040), Expect = 0.0
Identities = 590/717 (82%), Positives = 643/717 (89%), Gaps = 13/717 (1%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDETVIYKQIGKVS 60
MCGIFGYCN+LVE+SRGEIIDTLV+GLQRLEYRGYDSTGIAIDGD D T IYKQIGKVS
Sbjct: 1 MCGIFGYCNYLVERSRGEIIDTLVDGLQRLEYRGYDSTGIAIDGDEADSTFIYKQIGKVS 60
Query: 61 ALKKEIEAHKPNRDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVVHNGIITN 120
ALK+EI PNRD FV+HCGIAHTRWATHG P+QVNCHP RSDP FVVVHNGIITN
Sbjct: 61 ALKEEITKQNPNRDVTFVSHCGIAHTRWATHGRPEQVNCHPQRSDPEDQFVVVHNGIITN 120
Query: 121 FRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQELEGSYG 180
FR+L+ LL NKGYKFESDTDTECIAKL+ H+Y+TNL+NGHD DFHELT VL ELEGSYG
Sbjct: 121 FRELKTLLINKGYKFESDTDTECIAKLYLHLYNTNLQNGHDLDFHELTKLVLLELEGSYG 180
Query: 181 LLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPDSEQ-LPDLPV--NNECNL 237
LLCKS HYPNE+IATRKGSPLLIGVKSEKKLKVDFVDVEFP+ P++P+ NN+
Sbjct: 181 LLCKSCHYPNEVIATRKGSPLLIGVKSEKKLKVDFVDVEFPEENAGQPEIPLKSNNKSFG 240
Query: 238 LN----------DADRSLLPLAGDESTLRRSQSRAFLSEDGSPSPIEFFLSSDAASIVKH 287
L + +LLP+A +E LR SQSRAFLSEDGSP+P+EFF+SSDAAS+VKH
Sbjct: 241 LGPKKAREFEAGSQNANLLPIAANEFNLRHSQSRAFLSEDGSPTPVEFFVSSDAASVVKH 300
Query: 288 TKKVLFLEDDDIAHIYDGELHIHRANKKLTESATRSIQTLEMELAQIMKGPYQHFMQKEI 347
TKKVLFLEDDD+AHIYDGELHIHR+ +++ S TRSIQTLEMELAQIMKGPY HFMQKEI
Sbjct: 301 TKKVLFLEDDDLAHIYDGELHIHRSRREVGASMTRSIQTLEMELAQIMKGPYDHFMQKEI 360
Query: 348 YEQPESTLNTMRGRIDFEHNLVNLGGLKSRLSAIRKARRLIMIACGTSYHSCLATRAIFE 407
YEQPEST NTMRGRID+E+N V LGGLK+ L +R+ARRLIMIACGTSYHSCLATRAIFE
Sbjct: 361 YEQPESTFNTMRGRIDYENNKVILGGLKAWLPVVRRARRLIMIACGTSYHSCLATRAIFE 420
Query: 408 ELTEIPVSVELASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLNYCLERGALTLGIVNS 467
EL++IPVSVELASDFLDRKCP+FRDDVC+FVSQSGETADTML+LNYCLERGALT+GIVNS
Sbjct: 421 ELSDIPVSVELASDFLDRKCPVFRDDVCVFVSQSGETADTMLALNYCLERGALTVGIVNS 480
Query: 468 VGSSISRSTHCGVHINAGPEIGVASTKAYTSQYIALVMVALSLSDDRVSKIERRNEIIQG 527
VGSSISR THCGVHINAGPEIGVASTKAYTSQYIALVM ALSLSDDRVSKI+RR EIIQG
Sbjct: 481 VGSSISRVTHCGVHINAGPEIGVASTKAYTSQYIALVMFALSLSDDRVSKIDRRIEIIQG 540
Query: 528 LKLIPGQIKEVLNVEPRIKELCAKELKDQKSLLLLGRGYQFASALEGALKIKEISYMHSE 587
LKLIPGQIK+VL +EPRIK+LCA ELKDQKSLLLLGRGYQFA+ALEGALKIKEISYMHSE
Sbjct: 541 LKLIPGQIKQVLKLEPRIKKLCATELKDQKSLLLLGRGYQFAAALEGALKIKEISYMHSE 600
Query: 588 GVLAGELKHGVLALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARKGHPIIICNENDEVWQ 647
GVLAGELKHGVLALVDE+LPIIAFGTRDSLFPKV+SSIEQV ARKGHPIIICNENDEVW
Sbjct: 601 GVLAGELKHGVLALVDENLPIIAFGTRDSLFPKVVSSIEQVTARKGHPIIICNENDEVWA 660
Query: 648 NKAKANNLITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVDFPRNLAKSVTVE 704
K+K+ +L TLEVPQTVDCLQGL+NIIPLQL SYWLAVN GIDVDFPRNLAKSVTVE
Sbjct: 661 QKSKSIDLQTLEVPQTVDCLQGLINIIPLQLMSYWLAVNKGIDVDFPRNLAKSVTVE 717
>SPBC12C2.11 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 696
Score = 835 bits (2157), Expect = 0.0
Identities = 422/709 (59%), Positives = 536/709 (75%), Gaps = 18/709 (2%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDETVIYKQIGKVS 60
MCGIFGY N+LVE+ RG I+ TLV+GL+RLEYRGYDS+G A+DGD ++ +++K++G VS
Sbjct: 1 MCGIFGYINYLVERDRGYILKTLVKGLKRLEYRGYDSSGCAVDGDEGEDFIMFKEVGNVS 60
Query: 61 ALKKEIEAHKPNRDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVVHNGIITN 120
L+ I+ N+ F+ HC I+HTRWATHG P +NCHP RSDP F+VVHNGI+TN
Sbjct: 61 KLEASIKGSNVNKSTKFINHCAISHTRWATHGIPSPINCHPQRSDPHSEFIVVHNGILTN 120
Query: 121 FRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQELEGSYG 180
+R+LR +L ++G FES+TDTEC+AKL K IYDT DF L V +ELEG+Y
Sbjct: 121 YRELRTVLESRGMVFESETDTECVAKLAKFIYDTT----PGVDFTSLAKLVFRELEGAYA 176
Query: 181 LLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPD-SEQLPDLPVNNECNLLN 239
LL KS+HYP E++ATR+GSPL++GVKSE+KLKVDFVDVEFP+ +E LP P + +
Sbjct: 177 LLIKSSHYPGEVVATRRGSPLIVGVKSEQKLKVDFVDVEFPEPAEGLPGTPKPTSLHPVF 236
Query: 240 DADRSLLPLAGDE-STLRRSQSRAFLSEDGSPSPIEFFLSSDAASIVKHTKKVLFLEDDD 298
+ L GD+ L R+QSRAF+S +G P PIE+F +SDA I+++TK+V+FLEDDD
Sbjct: 237 SNPATNGMLRGDKPDLLHRAQSRAFVSGEGVPGPIEYFFASDATPIIEYTKRVMFLEDDD 296
Query: 299 IAHIYDGELHIHRANKKLTESATRSIQTLEMELAQIMKGPYQHFMQKEIYEQPESTLNTM 358
IAH+ DGELH+HR ++ S TR+I+TLEME+A +MKG Y H+M KEI EQP+S LNTM
Sbjct: 297 IAHVRDGELHVHRLRREGGGSTTRTIETLEMEIASVMKGNYDHYMIKEICEQPDSLLNTM 356
Query: 359 RGRIDFEHNLVNLGGLKSRLSAIRKARRLIMIACGTSYHSCLATRAIFEELTEIPVSVEL 418
RGR++F + LV LGGL+S IRK+RRLI +ACGTSYHSC+A R +FEELT IPV VEL
Sbjct: 357 RGRVNFVNRLVTLGGLESYYDIIRKSRRLIFVACGTSYHSCVAVRPLFEELTNIPVVVEL 416
Query: 419 ASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLNYCLERGALTLGIVNSVGSSISRSTHC 478
ASDF+DR +FRDD IFVSQSGETAD++L+L Y LE GAL +G+VN VGSSISR THC
Sbjct: 417 ASDFVDRCPSVFRDDTFIFVSQSGETADSLLALQYTLENGALAIGVVNCVGSSISRKTHC 476
Query: 479 GVHINAGPEIGVASTKAYTSQYIALVMVALSLSDDRVSKIERRNEIIQGLKLIPGQIKEV 538
GVHINAGPEI VASTKAYTSQY+ALV++AL LS D VS++ERRNEII GL I +++E
Sbjct: 477 GVHINAGPEICVASTKAYTSQYVALVLMALYLSRDSVSRLERRNEIIDGLAEIGEKVQET 536
Query: 539 LNVEPRIKELCAKELKDQKSLLLLGRGYQFASALEGALKIKEISYMHSEGVLAGELKHGV 598
L++ IK+ ++L ++ +L++GRGY +A+ALEGALK+KEISY H+EGVLAGELKHGV
Sbjct: 537 LHLNAAIKQTAIEQLINKDKMLIIGRGYHYATALEGALKVKEISYTHAEGVLAGELKHGV 596
Query: 599 LALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARKGHPIIICNENDEVWQNKAKANNL--- 655
LALVD D+PI+ D FPK ++ EQV AR G PIII ++ K +NL
Sbjct: 597 LALVDNDMPIVMLLPDDYNFPKAWNAFEQVRARGGKPIIITDK---------KLDNLEGF 647
Query: 656 ITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVDFPRNLAKSVTVE 704
++VP+TVDCLQG+LN+IP QL SYWLAV G +VD PRNLAKSVTVE
Sbjct: 648 TIIKVPKTVDCLQGILNVIPFQLLSYWLAVKRGHNVDQPRNLAKSVTVE 696
>Hs4826742 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 682
Score = 772 bits (1993), Expect = 0.0
Identities = 402/709 (56%), Positives = 521/709 (72%), Gaps = 32/709 (4%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGD----REDETVIYKQI 56
MCGIF Y N+ V ++R EI +TL++GLQRLEYRGYDS G+AIDG+ +E + K+
Sbjct: 1 MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNHEVKERHIQLVKKR 60
Query: 57 GKVSALKKEI-EAHKPNRDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVVHN 115
GKV AL +E+ + + F TH GIAHTRWATHG P VN HP RSD FVV+HN
Sbjct: 61 GKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVVIHN 120
Query: 116 GIITNFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQEL 175
GIITN++DLR+ L +KGY+FES+TDTE IAKL K+++D + D F L +V+Q+L
Sbjct: 121 GIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDN--RETEDITFSTLVERVIQQL 178
Query: 176 EGSYGLLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPDSEQLPDLPVNNEC 235
EG++ L+ KS HYP E +ATR+GSPLLIGV+S+ KL +EQ+P L C
Sbjct: 179 EGAFALVFKSVHYPGEAVATRRGSPLLIGVRSKYKLS----------TEQIPIL--YRTC 226
Query: 236 NLLNDADRSLLPLAGDESTLRRSQSRAFLSEDGSPSPIEFFLSSDAASIVKHTKKVLFLE 295
L N + ++ ++R S A L G + +EFF +SDA++I++HT +V+FLE
Sbjct: 227 TLENVKNIC-------KTRMKRLDSSACLHAVGDKA-VEFFFASDASAIIEHTNRVIFLE 278
Query: 296 DDDIAHIYDGELHIHRANKKLTESATRSIQTLEMELAQIMKGPYQHFMQKEIYEQPESTL 355
DDDIA + DG+L IHR + ++ +R+IQTL+MEL QIMKG + FMQKEI+EQPES
Sbjct: 279 DDDIAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVF 338
Query: 356 NTMRGRIDFEHNLVNLGGLKSRLSAIRKARRLIMIACGTSYHSCLATRAIFEELTEIPVS 415
NTMRGR++FE N V LGGLK L IR+ RRLI+I CGTSYH+ +ATR + EELTE+PV
Sbjct: 339 NTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVM 398
Query: 416 VELASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLNYCLERGALTLGIVNSVGSSISRS 475
VELASDFLDR P+FRDDVC F+SQSGETADT+L+L YC +RGALT+G+ N+VGSSISR
Sbjct: 399 VELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGVTNTVGSSISRE 458
Query: 476 THCGVHINAGPEIGVASTKAYTSQYIALVMVALSLSDDRVSKIERRNEIIQGLKLIPGQI 535
T CGVHINAGPEIGVASTKAYTSQ+I+LVM L +S+DR+S RR EII+GL+ +P I
Sbjct: 459 TDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELI 518
Query: 536 KEVLNVEPRIKELCAKELKDQKSLLLLGRGYQFASALEGALKIKEISYMHSEGVLAGELK 595
KEVL++E +I +L A EL Q+SLL++GRGY +A+ LEGALKIKEI+YMHSEG+LAGELK
Sbjct: 519 KEVLSLEEKIHDL-ALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELK 577
Query: 596 HGVLALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARKGHPIIICNENDEVWQNKAKANNL 655
HG LAL+D+ +P+I +D F K ++++QV AR+G PII+C+++D ++
Sbjct: 578 HGPLALIDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDD----TESSKFAY 633
Query: 656 ITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVDFPRNLAKSVTVE 704
T+E+P TVDCLQG+L++IPLQL S+ LAV G DVDFPRNLAKSVTVE
Sbjct: 634 KTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE 682
>Hs4503981 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 681
Score = 762 bits (1968), Expect = 0.0
Identities = 386/713 (54%), Positives = 511/713 (71%), Gaps = 41/713 (5%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDE-------TVIY 53
MCGIF Y N+ V ++R EI++TL++GLQRLEYRGYDS G+ DG + + T +
Sbjct: 1 MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKTQLI 60
Query: 54 KQIGKVSALKKEIEAHKP-NRDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVV 112
K+ GKV AL +E+ + + D F H GIAHTRWATHGEP VN HP RSD + F+V
Sbjct: 61 KKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIV 120
Query: 113 VHNGIITNFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVL 172
+HNGIITN++DL++ L +KGY FES+TDTE IAKL K++YD + D F L +V+
Sbjct: 121 IHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDN--RESQDTSFTTLVERVI 178
Query: 173 QELEGSYGLLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPDSEQLPDLPVN 232
Q+LEG++ L+ KS H+P + + TR+GSPLLIGV+SE KL D + + + +
Sbjct: 179 QQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTGKDK-----K 233
Query: 233 NECNLLN-DADRSLLPLAGDESTLRRSQSRAFLSEDGSPSPIEFFLSSDAASIVKHTKKV 291
CNL D+ L P+ +E++ +SDA+++++HT +V
Sbjct: 234 GSCNLSRVDSTTCLFPV--------------------EEKAVEYYFASDASAVIEHTNRV 273
Query: 292 LFLEDDDIAHIYDGELHIHRANKKLTESATRSIQTLEMELAQIMKGPYQHFMQKEIYEQP 351
+FLEDDD+A + DG L IHR + + R++QTL+MEL QIMKG + FMQKEI+EQP
Sbjct: 274 IFLEDDDVAAVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQP 333
Query: 352 ESTLNTMRGRIDFEHNLVNLGGLKSRLSAIRKARRLIMIACGTSYHSCLATRAIFEELTE 411
ES +NTMRGR++F+ VNLGGLK + I++ RRLI+IACGTSYH+ +ATR + EELTE
Sbjct: 334 ESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTE 393
Query: 412 IPVSVELASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLNYCLERGALTLGIVNSVGSS 471
+PV VELASDFLDR P+FRDDVC F+SQSGETADT++ L YC ERGALT+GI N+VGSS
Sbjct: 394 LPVMVELASDFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSS 453
Query: 472 ISRSTHCGVHINAGPEIGVASTKAYTSQYIALVMVALSLSDDRVSKIERRNEIIQGLKLI 531
ISR T CGVHINAGPEIGVASTKAYTSQ+++LVM AL + DDR+S ERR EI+ GLK +
Sbjct: 454 ISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRL 513
Query: 532 PGQIKEVLNVEPRIKELCAKELKDQKSLLLLGRGYQFASALEGALKIKEISYMHSEGVLA 591
P IKEVL+++ I++L A EL QKS+L++GRGY +A+ LEGALKIKEI+YMHSEG+LA
Sbjct: 514 PDLIKEVLSMDDEIQKL-ATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILA 572
Query: 592 GELKHGVLALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARKGHPIIICNENDEVWQNKAK 651
GELKHG LALVD+ +P+I RD + K ++++QV+AR+G P++IC++ D +
Sbjct: 573 GELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKED----TETI 628
Query: 652 ANNLITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVDFPRNLAKSVTVE 704
N T++VP +VDCLQG+L++IPLQL ++ LAV G DVDFPRNLAKSVTVE
Sbjct: 629 KNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE 681
>7289004 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 694
Score = 745 bits (1924), Expect = 0.0
Identities = 376/707 (53%), Positives = 511/707 (72%), Gaps = 16/707 (2%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDETVIYKQIGKVS 60
MCGIF Y N+L KSR E++D LV GL+RLEYRGYDSTG+AID V+ K+ GKV
Sbjct: 1 MCGIFAYLNYLTPKSRQEVLDLLVTGLKRLEYRGYDSTGVAIDSPDNKNIVMVKRTGKVK 60
Query: 61 ALKKEIEAHKPNRDAH--FVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVVHNGII 118
L++ I+ H R+ +TH GIAHTRWATHG P + N HPHRSD FVVVHNGII
Sbjct: 61 VLEEAIQEHFSGREYSEPVLTHVGIAHTRWATHGVPCEKNSHPHRSDDENGFVVVHNGII 120
Query: 119 TNFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQELEGS 178
TN+ D++ L+ +GY+FESDTDTE AKL H++ T+ F EL Q + ++EG+
Sbjct: 121 TNYNDVKTFLSKRGYEFESDTDTEVFAKLVHHLWKTHPTYS----FRELVEQAILQVEGA 176
Query: 179 YGLLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPDSEQLPDLPVNNECNLL 238
+ + KS ++P E +A+R+ SPLL+G+K++ +L D + + + ++ L + + +
Sbjct: 177 FAIAVKSKYFPGECVASRRSSPLLVGIKTKTRLATDHIPILYGKDDK--KLCTDQDADSG 234
Query: 239 NDADRSLLPLAGDESTLRRSQSRA-FLSEDGSPSPIEFFLSSDAASIVKHTKKVLFLEDD 297
D + + L RS+S + F+ + +E+F +SDA+++++HT +V++LEDD
Sbjct: 235 KPQDIRPHGQSRELPVLPRSESTSEFMPLE--EKEVEYFFASDASAVIEHTNRVIYLEDD 292
Query: 298 DIAHIYDGELHIHRANKKLTESATRSIQTLEMELAQIMKGPYQHFMQKEIYEQPESTLNT 357
D+A + DG L IHR K L + R I TL+ME+ QIMKG Y +FMQKEI+EQP+S +NT
Sbjct: 293 DVAAVRDGTLSIHRLKKSLDDPHAREITTLKMEIQQIMKGNYDYFMQKEIFEQPDSVVNT 352
Query: 358 MRGRIDFEHNLVNLGGLKSRLSAIRKARRLIMIACGTSYHSCLATRAIFEELTEIPVSVE 417
MRGR+ F+ N + LGG+K + I++ RRL++I CGTSYHS +ATR + EELTE+PV VE
Sbjct: 353 MRGRVRFDGNAIVLGGIKDYIPEIKRCRRLMLIGCGTSYHSAVATRQLLEELTELPVMVE 412
Query: 418 LASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLNYCLERGALTLGIVNSVGSSISRSTH 477
LASDFLDR PIFRDDVC F+SQSGETADT+++L YC +RGAL +GI N+VGSSI R +H
Sbjct: 413 LASDFLDRNTPIFRDDVCFFISQSGETADTLMALRYCKQRGALIVGITNTVGSSICRESH 472
Query: 478 CGVHINAGPEIGVASTKAYTSQYIALVMVALSLSDDRVSKIERRNEIIQGLKLIPGQIKE 537
CGVHINAGPEIGVASTKAYTSQ+I+LVM AL +S+DR+S +RR EI+Q L + QI++
Sbjct: 473 CGVHINAGPEIGVASTKAYTSQFISLVMFALVMSEDRLSLQQRRLEILQALSKLADQIRD 532
Query: 538 VLNVEPRIKELCAKELKDQKSLLLLGRGYQFASALEGALKIKEISYMHSEGVLAGELKHG 597
VL ++ ++KEL AK+L KSLL++GRGY FA+ LEGALK+KE++YMHSEG++AGELKHG
Sbjct: 533 VLQLDSKVKEL-AKDLYQHKSLLIMGRGYNFATCLEGALKVKELTYMHSEGIMAGELKHG 591
Query: 598 VLALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARKGHPIIICNENDEVWQNKAKANNLIT 657
LALVD+ +P++ RD ++ K +++++QV +RKG PIIIC E DE + KA +
Sbjct: 592 PLALVDDSMPVLMIVLRDPVYVKCMNALQQVTSRKGCPIIICEEGDE----ETKAFSSRH 647
Query: 658 LEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVDFPRNLAKSVTVE 704
LE+P+TVDCLQG+L +IP+QL SY +AV G DVD PRNLAKSVTVE
Sbjct: 648 LEIPRTVDCLQGILTVIPMQLLSYHIAVLRGCDVDCPRNLAKSVTVE 694
>7301670 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 683
Score = 731 bits (1888), Expect = 0.0
Identities = 377/712 (52%), Positives = 504/712 (69%), Gaps = 37/712 (5%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDET---VIYKQIG 57
MCGIF Y N+L KSR E++D L++GL+RLEYRGYDSTGIAID E ++ K+ G
Sbjct: 1 MCGIFAYLNYLTPKSRQEVLDLLLQGLKRLEYRGYDSTGIAIDALNSGEAQSIMLVKRTG 60
Query: 58 KVSALKKEIEAHKPNRDAHFV--THCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVVHN 115
KV L+ + +D TH GIAHTRWATHG P +VN HP RSD +FVVVHN
Sbjct: 61 KVKVLEDAVAEVCRGQDYSLPIDTHIGIAHTRWATHGVPSEVNSHPQRSDEDNSFVVVHN 120
Query: 116 GIITNFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQEL 175
GIITN++D++ LL +GY FESDTDTE IAKL H++ + G+ F EL Q +Q+L
Sbjct: 121 GIITNYKDVKTLLEKRGYVFESDTDTEVIAKLVHHLWQQH--PGYT--FGELVEQAIQQL 176
Query: 176 EGSYGLLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPDSEQLPDLPVNNEC 235
EG++ + KS H+P E +A+R+GSPLL+G+K++ KL D + + + + + P
Sbjct: 177 EGAFAIAFKSKHFPGECVASRRGSPLLVGIKAKTKLATDHIPILYAKAHRPHGQPQQQAY 236
Query: 236 NLL--NDADRSLLPLAGDESTLRRSQSRAFLSEDGSPSPIEFFLSSDAASIVKHTKKVLF 293
LL D + PL E +E+F +SDA+++++HT +V++
Sbjct: 237 QLLPPGDCNAEFQPLERKE--------------------VEYFFASDASAVIEHTNRVIY 276
Query: 294 LEDDDIAHIY-DGELHIHRANKKLTESATRSIQTLEMELAQIMKGPYQHFMQKEIYEQPE 352
LEDDD+A + DG L IHR NK + R I TL+ME+ QIMKG Y +FM KEI+EQPE
Sbjct: 277 LEDDDVAAVKSDGTLSIHRLNKSSDDPHAREIITLKMEIQQIMKGNYDYFMLKEIFEQPE 336
Query: 353 STLNTMRGRIDFEHNLVNLGGLKSRLSAIRKARRLIMIACGTSYHSCLATRAIFEELTEI 412
S +NTMRGR+ F+ V LGG+K + I++ RRL++IACGTSYHS +ATR + EELTE+
Sbjct: 337 SVVNTMRGRMRFDTQTVVLGGIKEYIPEIKRCRRLMLIACGTSYHSAVATRQLLEELTEL 396
Query: 413 PVSVELASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLNYCLERGALTLGIVNSVGSSI 472
PV VELASDFLDR PIFRDDVC F+SQSGETADT+++L YC +RGAL +G+ N+VGSSI
Sbjct: 397 PVMVELASDFLDRNTPIFRDDVCFFISQSGETADTLMALRYCKQRGALIVGVTNTVGSSI 456
Query: 473 SRSTHCGVHINAGPEIGVASTKAYTSQYIALVMVALSLSDDRVSKIERRNEIIQGLKLIP 532
R +HCGVHINAGPEIGVASTKAYTSQ+I+LVM AL +S+DR+S +RR EII GL +
Sbjct: 457 CRESHCGVHINAGPEIGVASTKAYTSQFISLVMFALVMSEDRLSLQQRRLEIIDGLSQLD 516
Query: 533 GQIKEVLNVEPRIKELCAKELKDQKSLLLLGRGYQFASALEGALKIKEISYMHSEGVLAG 592
I+ VL + ++++L AKEL + KSLL++GRG+ FA+ LEGALK+KE++YMHSEG+LAG
Sbjct: 517 EHIRTVLKLNSQVQQL-AKELYEHKSLLIMGRGFNFATCLEGALKVKELTYMHSEGILAG 575
Query: 593 ELKHGVLALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARKGHPIIICNENDEVWQNKAKA 652
ELKHG LALVD+++P++ RD ++ K +++++QV +RKG PI+IC E D N+ +
Sbjct: 576 ELKHGPLALVDKEMPVLMIVLRDPVYTKCMNALQQVTSRKGRPILICEEGD----NETMS 631
Query: 653 NNLITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVDFPRNLAKSVTVE 704
+ +L++P+TVDCLQG+L +IPLQL SY +AV G DVD PRNLAKSVTVE
Sbjct: 632 FSTRSLQIPRTVDCLQGVLTVIPLQLLSYHIAVLRGCDVDCPRNLAKSVTVE 683
>CE27915 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 712
Score = 713 bits (1841), Expect = 0.0
Identities = 381/724 (52%), Positives = 503/724 (68%), Gaps = 32/724 (4%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDET-----VIYKQ 55
MCGIF Y NFL K R EI+D LV+GLQR+EYRGYDS GIAIDG E E+ + ++
Sbjct: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK 60
Query: 56 IGKVSALKKEIEAHKPN--RDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVV 113
GKVS L I+ + D + HCGIAHTRWATHG P+ VN HPHRS+ F+VV
Sbjct: 61 AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV 120
Query: 114 HNGIITNFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQ 173
HNGIITN+R++++ L KG+KFES+TDTE IAKL +HI+D D F +L V+Q
Sbjct: 121 HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHDRY----PDFSFRQLVETVIQ 176
Query: 174 ELEGSYGLLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPDSEQLPD----- 228
+LEG++ L KS+ +P +++A+R+GSPLL+G+KS +L+ + V F +
Sbjct: 177 QLEGAFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKGRRFMSNHATH 236
Query: 229 -------LPVNNECNLLNDADRSLLPLAGDESTLRRSQSRAFLSEDGSPSPIEFFLSSDA 281
+ N L+ A RS A E + + R F S+D +E+F++SDA
Sbjct: 237 LRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDWE---VEYFVASDA 293
Query: 282 ASIVKHTKKVLFLEDDDIAHIYDGELHIHRANKKLTESAT-RSIQTLEMELAQIMKGPYQ 340
A+I++HTK+VLFLEDDD+A + DG L IHR ++ R ++ LEMEL +IMKG ++
Sbjct: 294 AAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLLEMELQEIMKGSFK 353
Query: 341 HFMQKEIYEQPESTLNTMRGRIDFEHNLVNLGGLKSRLSAIRKARRLIMIACGTSYHSCL 400
+MQKEI+EQP+S +NTMRGR+ V LGG+K L I++ RRLIM+ACGTSYHS +
Sbjct: 354 TYMQKEIFEQPDSVVNTMRGRV-LPSGQVVLGGIKEYLPDIKRCRRLIMVACGTSYHSAI 412
Query: 401 ATRAIFEELTEIPVSVELASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLNYCLERGAL 460
A R I EEL+E+PV VELASDFLDR+ PIFRDDVC+F+SQSGETADT+L+L YC RGAL
Sbjct: 413 ACRQILEELSELPVVVELASDFLDRETPIFRDDVCLFISQSGETADTLLALRYCKPRGAL 472
Query: 461 TLGIVNSVGSSISRSTHCGVHINAGPEIGVASTKAYTSQYIALVMVALSLSDDRVSKIER 520
T+G+ N+VGSSI R +HCG+HINAGPEIGVASTKAYTSQ ++L+M AL+LSDDR+S +R
Sbjct: 473 TIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFALTLSDDRISMAKR 532
Query: 521 RNEIIQGLKLIPGQIKEVLNVEPRIKELCAKELKDQKSLLLLGRGYQFASALEGALKIKE 580
R EII L +P I+EVL ++ ++ ++ AK++ +KSLL++GRG FA+ LEGALKIKE
Sbjct: 533 REEIIDALNDLPELIREVLQLDEKVLDI-AKQIYKEKSLLIMGRGLNFATCLEGALKIKE 591
Query: 581 ISYMHSEGVLAGELKHGVLALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARKGHPIIICN 640
+SYMH EG+++GELKHG LA+VDE L I D ++ K L++++QV+ARKG PIII
Sbjct: 592 LSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQVVARKGAPIIIA- 650
Query: 641 ENDEVWQNKAKANNLITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVDFPRNLAKS 700
D A L VP+TVDC+Q +L +IPLQL SY +A NG +VD PRNLAKS
Sbjct: 651 --DCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAKS 708
Query: 701 VTVE 704
VTVE
Sbjct: 709 VTVE 712
>CE03255 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 710
Score = 713 bits (1841), Expect = 0.0
Identities = 377/724 (52%), Positives = 504/724 (69%), Gaps = 34/724 (4%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDET-----VIYKQ 55
MCGIF Y NFL K R EI+D LV+GLQR+EYRGYDS GIAIDG + E + ++
Sbjct: 1 MCGIFAYLNFLAPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNDIENPHSKIALLRK 60
Query: 56 IGKVSALKKEIEAH--KPNRDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVV 113
GKVS L I+ + K N D + HCGIAHTRWATHG P+ VN HPHRS+ + F+VV
Sbjct: 61 RGKVSVLNDYIKENNEKLNMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDNNEFLVV 120
Query: 114 HNGIITNFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQ 173
HNGIITN+R++++ L KG+KFES+TDTE IAKL +H++D D F +L V+Q
Sbjct: 121 HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLTQHVHDRY----PDFSFRQLVETVIQ 176
Query: 174 ELEGSYGLLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPDS---------- 223
+LEG++ L KS+ +P +++A+R+GSPLL+G+KS L V +
Sbjct: 177 QLEGAFALAFKSSRFPGQLVASRRGSPLLVGIKSNSTLHTSHFPVSYSKGRCFMSNNATH 236
Query: 224 --EQLPDLPVNNECNLLNDADRSLLPLAGDESTLRRSQSRAFLSEDGSPSPIEFFLSSDA 281
E+ + N L+ A R+ P + S +R F D + +E+F++SDA
Sbjct: 237 LREETSFVETPNNILDLSIAVRN--PSGSAKLPDNNSTTRPF---DSTDFEVEYFIASDA 291
Query: 282 ASIVKHTKKVLFLEDDDIAHIYDGELHIHRANKKLTESAT-RSIQTLEMELAQIMKGPYQ 340
A+I++HTK+VLFLEDDD+A + DG L IHR ++ R +Q LE+E+ +IMKG Y+
Sbjct: 292 AAIIEHTKQVLFLEDDDVAFVEDGSLTIHRISRHADSGEQKREVQLLELEIQEIMKGSYK 351
Query: 341 HFMQKEIYEQPESTLNTMRGRIDFEHNLVNLGGLKSRLSAIRKARRLIMIACGTSYHSCL 400
FMQKEI+EQPES +NTMRGR+ V LGGLK L AI++ RRLIM+ACGTSYHS +
Sbjct: 352 TFMQKEIFEQPESVVNTMRGRV-LPSGQVVLGGLKEYLPAIKRCRRLIMVACGTSYHSAI 410
Query: 401 ATRAIFEELTEIPVSVELASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLNYCLERGAL 460
A R + EEL+E+PV VELASDFLDR+ PIFR+DVC+F+SQSGETADT+++L YC RGAL
Sbjct: 411 ACRQVLEELSELPVVVELASDFLDRETPIFRNDVCLFISQSGETADTLMALRYCKPRGAL 470
Query: 461 TLGIVNSVGSSISRSTHCGVHINAGPEIGVASTKAYTSQYIALVMVALSLSDDRVSKIER 520
T+G+ N+VGSSI R +HCG+HINAGPEIGVASTKAYTSQ ++L++ AL++S+DR+SK++R
Sbjct: 471 TIGVTNTVGSSIGRESHCGIHINAGPEIGVASTKAYTSQIVSLLLFALTISEDRISKMKR 530
Query: 521 RNEIIQGLKLIPGQIKEVLNVEPRIKELCAKELKDQKSLLLLGRGYQFASALEGALKIKE 580
R EII L +P I++VL+++ ++ ++ + KD KSLL++GRG FA+ LEGALKIKE
Sbjct: 531 RAEIIDALNNLPILIRDVLDLDDQVLKIAEQIYKD-KSLLIMGRGLNFATCLEGALKIKE 589
Query: 581 ISYMHSEGVLAGELKHGVLALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARKGHPIIICN 640
+SYMH EG+++GELKHG LA+VDE L I D ++ K L++++QV+ARKG PIII
Sbjct: 590 LSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDHVYKKSLNALQQVVARKGAPIIIA- 648
Query: 641 ENDEVWQNKAKANNLITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVDFPRNLAKS 700
D A L VP+TVDC+Q +L +IPLQL SY +A NG +VD PRNLAKS
Sbjct: 649 --DSSVPESDLAGMKHVLRVPRTVDCVQNILTVIPLQLLSYHIAELNGANVDRPRNLAKS 706
Query: 701 VTVE 704
VTVE
Sbjct: 707 VTVE 710
>CE03144 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 725
Score = 709 bits (1830), Expect = 0.0
Identities = 384/737 (52%), Positives = 506/737 (68%), Gaps = 45/737 (6%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDET-----VIYKQ 55
MCGIF Y NFL K R EI+D LV+GLQR+EYRGYDS GIAIDG E E+ + ++
Sbjct: 1 MCGIFAYLNFLTPKKRSEIVDILVQGLQRMEYRGYDSAGIAIDGSNEIESPHSSVALLRK 60
Query: 56 IGKVSALKKEIEAHKPN--RDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVV 113
GKVS L I+ + D + HCGIAHTRWATHG P+ VN HPHRS+ F+VV
Sbjct: 61 AGKVSVLSDFIKESSSDLDMDMEYNIHCGIAHTRWATHGSPRDVNSHPHRSNDKNEFLVV 120
Query: 114 HNGIITNFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQ 173
HNGIITN+R++++ L KG+KFES+TDTE IAKL +HI+D D F +L V+Q
Sbjct: 121 HNGIITNYREIKEYLEKKGHKFESETDTEVIAKLAQHIHD----RYPDFSFRQLVETVIQ 176
Query: 174 ELEGSYGLLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFP--------DSEQ 225
+LEG++ L KS+ +P +++A+R+GSPLL+G+KS +L+ + V F D +Q
Sbjct: 177 QLEGAFALAFKSSRFPGQLVASRRGSPLLVGIKSNSRLQTNHFPVSFSKDAGWKWGDEKQ 236
Query: 226 LPDLP-VNNECNLLND----------------ADRSLLPLAGDESTLRRSQSRAFLSEDG 268
++N L D A RS A E + + R F S+D
Sbjct: 237 TDGRRFMSNHATHLRDETSFVETPNNILDLSIAVRSSNGSAKMEISDSTTAVRPFDSDDW 296
Query: 269 SPSPIEFFLSSDAASIVKHTKKVLFLEDDDIAHIYDGELHIHRANKKLTE-SATRSIQTL 327
+E+F++SDAA+I++HTK+VLFLEDDD+A + DG L IHR ++ R ++ L
Sbjct: 297 E---VEYFVASDAAAIIEHTKQVLFLEDDDVAFVEDGALTIHRISRHADNGEQKREVKLL 353
Query: 328 EMELAQIMKGPYQHFMQKEIYEQPESTLNTMRGRIDFEHNLVNLGGLKSRLSAIRKARRL 387
EMEL +IMKG ++ +MQKEI+EQP+S +NTMRGR+ V LGG+K L I++ RRL
Sbjct: 354 EMELQEIMKGSFKTYMQKEIFEQPDSVVNTMRGRV-LPSGQVVLGGIKEYLPDIKRCRRL 412
Query: 388 IMIACGTSYHSCLATRAIFEELTEIPVSVELASDFLDRKCPIFRDDVCIFVSQSGETADT 447
IM+ACGTSYHS +A R I EEL+E+PV VELASDFLDR+ PIFRDDVC+F+SQSGETADT
Sbjct: 413 IMVACGTSYHSAIACRQILEELSELPVVVELASDFLDRETPIFRDDVCLFISQSGETADT 472
Query: 448 MLSLNYCLERGALTLGIVNSVGSSISRSTHCGVHINAGPEIGVASTKAYTSQYIALVMVA 507
+L+L YC RGALT+G+ N+VGSSI R +HCG+HINAGPEIGVASTKAYTSQ ++L+M A
Sbjct: 473 LLALRYCKPRGALTIGVTNTVGSSICRESHCGIHINAGPEIGVASTKAYTSQILSLLMFA 532
Query: 508 LSLSDDRVSKIERRNEIIQGLKLIPGQIKEVLNVEPRIKELCAKELKDQKSLLLLGRGYQ 567
L+LSDDR+S +RR EII L +P I+EVL ++ ++ ++ AK++ +KSLL++GRG
Sbjct: 533 LTLSDDRISMAKRREEIIDALNDLPELIREVLQLDEKVLDI-AKQIYKEKSLLIMGRGLN 591
Query: 568 FASALEGALKIKEISYMHSEGVLAGELKHGVLALVDEDLPIIAFGTRDSLFPKVLSSIEQ 627
FA+ LEGALKIKE+SYMH EG+++GELKHG LA+VDE L I D ++ K L++++Q
Sbjct: 592 FATCLEGALKIKELSYMHCEGIMSGELKHGPLAMVDEFLSICMVVCNDRVYKKSLNALQQ 651
Query: 628 VIARKGHPIIICNENDEVWQNKAKANNLITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNN 687
V+ARKG PIII D A L VP+TVDC+Q +L +IPLQL SY +A N
Sbjct: 652 VVARKGAPIIIA---DCTVPEGDLAGMKHILRVPKTVDCVQNILTVIPLQLLSYHIAELN 708
Query: 688 GIDVDFPRNLAKSVTVE 704
G +VD PRNLAKSVTVE
Sbjct: 709 GANVDRPRNLAKSVTVE 725
>ECU07g1280 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 699
Score = 687 bits (1774), Expect = 0.0
Identities = 369/719 (51%), Positives = 487/719 (67%), Gaps = 35/719 (4%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDETVIYKQIGKVS 60
MCGIFGY NF E+S+ EI + ++ GL+R+EYRGYDS G I + + + +GKV+
Sbjct: 1 MCGIFGYANFSKERSKDEIANIMINGLKRIEYRGYDSAGFCITDNTDRNFARIRAVGKVN 60
Query: 61 ALKKEIEAHKPNRDA--HFVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVVHNGII 118
+L EI+ + + D + H IAHTRWATHG+P N HP SD + +F+VVHNGII
Sbjct: 61 SLY-EIKNSQTSVDLTRKVLNHVSIAHTRWATHGQPSIENSHPLSSDENNSFLVVHNGII 119
Query: 119 TNFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQELEGS 178
TN++DL+ L KG+ FESDTDTEC AKL + Y + + DF + V++ EG+
Sbjct: 120 TNYKDLKVYLKKKGFTFESDTDTECAAKLALYFYREMERKKEETDFVAIVKNVVKHCEGA 179
Query: 179 YGLLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPDSEQLPDLPVNNECNLL 238
+ + S+ +PNE++ RK SP+LIG+K K+ DF V + D
Sbjct: 180 FAFVFASSLFPNELVTVRKSSPVLIGLKPSGKMSFDFFGVNYGDPA-------------- 225
Query: 239 NDADRSLL--PLAGDESTLRR-SQSRAFLSED--------GSPSPIEFFLSSDAASIVKH 287
+D SLL PLA +S Q+ ++ D + P+E F++SDA+++++H
Sbjct: 226 DDTPTSLLDSPLAFSKSDRHGFDQNIDMMTRDVQDCTLHAHNKEPLEVFVASDASALIEH 285
Query: 288 TKKVLFLEDDDIAHIYDGELHIHRANKKLTESAT--RSIQTLEMELAQIMKGPYQHFMQK 345
T+KV+FLED+DI HI +G + IHR + K ES R ++T+E ELA IMKG Y H+M K
Sbjct: 286 TRKVIFLEDNDIVHISNGNISIHRMHSKAKESGPEIREVKTIETELAAIMKGNYDHYMIK 345
Query: 346 EIYEQPESTLNTMRGRIDFEHNLVNLGGLKSRLSAIRKARRLIMIACGTSYHSCLATRAI 405
EI EQ ES +NTMRGRI+FE V+LGGLK +S IRK++R+I +ACGTSYH+ LA RA+
Sbjct: 346 EINEQEESVVNTMRGRINFESLTVSLGGLKDHVSGIRKSQRIIFVACGTSYHASLANRAL 405
Query: 406 FEELTEIPVSVELASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLNYCLERGALTLGIV 465
EEL EIPVSVE+ASDFLDR PI R D FVSQSGETAD++++L YC+ GAL +GI
Sbjct: 406 LEELLEIPVSVEIASDFLDRAPPIMRSDCVFFVSQSGETADSVMALRYCMSMGALCVGIT 465
Query: 466 NSVGSSISRSTHCGVHINAGPEIGVASTKAYTSQYIALVMVALSLSDDRVSKIERRNEII 525
N+VGS+ISR T CGVHINAGPEIGVASTKAYTSQYIALV+VAL LSD + K RR EI+
Sbjct: 466 NTVGSTISRETACGVHINAGPEIGVASTKAYTSQYIALVLVALQLSDQNLVKQARRREIM 525
Query: 526 QGLKLIPGQIKEVLNVEPRIKELCAKELKDQKSLLLLGRGYQFASALEGALKIKEISYMH 585
+GLK I QI VL + +K L +KD SLLL+GRGYQ+ + +EGALKIKEI+Y+H
Sbjct: 526 EGLKNISSQINRVLELSTSVKSLANGPMKDDASLLLIGRGYQYPTCMEGALKIKEITYIH 585
Query: 586 SEGVLAGELKHGVLALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARKGHPIIICNENDEV 645
+EG+ AGELKHG +ALVD+ L II T+D L+ K +++EQ+ AR G PI+IC E ++
Sbjct: 586 AEGLAAGELKHGPIALVDDKLRIIFIATKDLLYDKTRNAMEQIFARGGRPIVICTE--DI 643
Query: 646 WQNKAKANNLITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVDFPRNLAKSVTVE 704
+ A+ + T VP+TVDCLQG+L +IPLQL SY LAV G + DFPRNLAKSVTVE
Sbjct: 644 SGDYAEYD---TFVVPKTVDCLQGILTVIPLQLLSYHLAVAKGYNADFPRNLAKSVTVE 699
>At3g24090 [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 691
Score = 658 bits (1698), Expect = 0.0
Identities = 358/718 (49%), Positives = 472/718 (64%), Gaps = 41/718 (5%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDET-VIYKQIGKV 59
MCGIF Y NF K R I+D L GL+RLEYRGYDS GIAID + ++++Q G +
Sbjct: 1 MCGIFAYLNFHANKERRYILDVLFNGLRRLEYRGYDSAGIAIDNSSPSSSPLVFRQAGNI 60
Query: 60 SALKKEIEAHKPNRDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVVHNGIIT 119
+L I N D F H GIAHTRWATHGEP N HP S P F+VVHNG+IT
Sbjct: 61 ESLVNSITNTDLNLDEVFYFHAGIAHTRWATHGEPAPRNSHPQSSGPGDDFLVVHNGVIT 120
Query: 120 NFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYD-TNLKNGHDPDFHELTMQVLQELEGS 178
N+ L++ L G+ FESDTDTE I KL K ++D N + G F E+ +V++ LEG+
Sbjct: 121 NYEVLKETLVRHGFTFESDTDTEVIPKLAKFVFDKANEEGGQTVTFCEVVFEVMRHLEGA 180
Query: 179 YGLLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPDSEQLPDLPVNNECNLL 238
Y L+ KS HYPNE+IA + GSPLL+GVK L ++ + F
Sbjct: 181 YALIFKSWHYPNELIACKLGSPLLLGVKVSNSLSLESRGLLFV----------------- 223
Query: 239 NDADRSLLPLAGDESTLRRSQSRAFLSEDGSPSPIEFFLSSDAASIVKHTKKVLFLEDDD 298
SLL L ES Q FLS++ P EFFLSSD ++V+HTKKVL +ED +
Sbjct: 224 -----SLLELDQGESNSHVFQDAHFLSKNDHPK--EFFLSSDPHALVEHTKKVLVIEDGE 276
Query: 299 IAHIYDGELHIHRANKKLTE--------SATRSIQTLEMELAQIMKGPYQHFMQKEIYEQ 350
+ ++ DG + I + + S R++ LEME+ QI KG Y H+MQKEI+EQ
Sbjct: 277 VVNLKDGGVSILKFENERGRCNGLSRPASVERALSVLEMEVEQISKGKYDHYMQKEIHEQ 336
Query: 351 PESTLNTMRGRI----DFEHNLVNLGGLKSRLSAIRKARRLIMIACGTSYHSCLATRAIF 406
PES TMRGR+ + V LGGLK L IR++RR++ I CGTSY++ LA+R I
Sbjct: 337 PESLTTTMRGRLIRGGSRKTKTVLLGGLKDHLKTIRRSRRIVFIGCGTSYNAALASRPIL 396
Query: 407 EELTEIPVSVELASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLNYCLERGALTLGIVN 466
EEL+ IPVS+E+ASD DR+ PI+R+D +FVSQSGETADT+L+L+Y E GAL +GI N
Sbjct: 397 EELSGIPVSMEIASDLWDRQGPIYREDTAVFVSQSGETADTLLALDYARENGALCVGITN 456
Query: 467 SVGSSISRSTHCGVHINAGPEIGVASTKAYTSQYIALVMVALSLSDDRVSKIERRNEIIQ 526
+VGSSI+R THCGVHINAG EIGVASTKAYTSQ + +VM+AL++ D +S +RR II
Sbjct: 457 TVGSSIARKTHCGVHINAGAEIGVASTKAYTSQIVVMVMLALAIGSDTISSQKRREAIID 516
Query: 527 GLKLIPGQIKEVLNVEPRIKELCAKELKDQKSLLLLGRGYQFASALEGALKIKEISYMHS 586
GL +P ++KEVL ++ +K+L A+ L D++SLL+ GRGY +A+ALEGALK+KE++ MHS
Sbjct: 517 GLLDLPYKVKEVLKLDDEMKDL-AQLLIDEQSLLVFGRGYNYATALEGALKVKEVALMHS 575
Query: 587 EGVLAGELKHGVLALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARKGHPIIICNENDEVW 646
EG+LAGE+KHG LALVDE+LPI TRD+ F K S I+Q+ ARKG I++C++ D
Sbjct: 576 EGILAGEMKHGPLALVDENLPIAVIATRDACFSKQQSVIQQLHARKGRLIVMCSKGDAA- 634
Query: 647 QNKAKANNLITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVDFPRNLAKSVTVE 704
+ + + + +EVPQ DCLQ ++NI+PLQL +Y L V G +VD PRNLAKSVT +
Sbjct: 635 -SVSSSGSCRAIEVPQVEDCLQPVINIVPLQLLAYHLTVLRGHNVDQPRNLAKSVTTQ 691
>YMR085w [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 432
Score = 546 bits (1407), Expect = e-155
Identities = 267/428 (62%), Positives = 341/428 (79%)
Query: 273 IEFFLSSDAASIVKHTKKVLFLEDDDIAHIYDGELHIHRANKKLTESATRSIQTLEMELA 332
+EF+LSSD AS+ ++ KV++LED+DIAHIYDGELHIH + + + R++Q LE+EL+
Sbjct: 1 MEFYLSSDCASLARYVSKVVYLEDNDIAHIYDGELHIHCSKIGSEDFSFRTVQKLELELS 60
Query: 333 QIMKGPYQHFMQKEIYEQPESTLNTMRGRIDFEHNLVNLGGLKSRLSAIRKARRLIMIAC 392
+I KGPY +FMQKEIYEQ E+T N MRGR+D N V LGGL++ L+ +R+A+R+IMIA
Sbjct: 61 KIKKGPYDNFMQKEIYEQCETTKNVMRGRVDAFTNRVVLGGLENWLTELRRAKRIIMIAS 120
Query: 393 GTSYHSCLATRAIFEELTEIPVSVELASDFLDRKCPIFRDDVCIFVSQSGETADTMLSLN 452
S+HSCLA R IFEEL E+PV+VELA DF+DR C IFR+DVCIFVS+SGET DT+ +LN
Sbjct: 121 KASFHSCLAARPIFEELMEVPVNVELALDFVDRNCCIFRNDVCIFVSRSGETTDTINALN 180
Query: 453 YCLERGALTLGIVNSVGSSISRSTHCGVHINAGPEIGVASTKAYTSQYIALVMVALSLSD 512
YC+++ A+T+G+VN GSSISR THCGVH N GPE G+A+TK+YTSQYIALVM+AL +S+
Sbjct: 181 YCIKKEAVTIGVVNCSGSSISRFTHCGVHTNTGPEKGIATTKSYTSQYIALVMIALWMSE 240
Query: 513 DRVSKIERRNEIIQGLKLIPGQIKEVLNVEPRIKELCAKELKDQKSLLLLGRGYQFASAL 572
D VSKIERR EIIQ L ++P QIKEVL +EP I ELC K+LK + LLLGRGYQFASAL
Sbjct: 241 DLVSKIERRKEIIQALTIVPSQIKEVLELEPLIIELCDKKLKQHDTFLLLGRGYQFASAL 300
Query: 573 EGALKIKEISYMHSEGVLAGELKHGVLALVDEDLPIIAFGTRDSLFPKVLSSIEQVIARK 632
EGA K+KEISY+HSE +L EL H VLA+ ++ PIIAF T+D+ PK+ S I+Q+I RK
Sbjct: 301 EGASKMKEISYVHSESILTNELGHRVLAVASDNPPIIAFATKDAFSPKIASCIDQIIERK 360
Query: 633 GHPIIICNENDEVWQNKAKANNLITLEVPQTVDCLQGLLNIIPLQLTSYWLAVNNGIDVD 692
G+PIIICN+ ++W+ + N++TLEVPQTVDCLQG+LN+IPLQL SYWLA+ I VD
Sbjct: 361 GNPIIICNKGHKIWEQDKQKGNVVTLEVPQTVDCLQGILNVIPLQLISYWLAIKKDIGVD 420
Query: 693 FPRNLAKS 700
PR+ A S
Sbjct: 421 LPRDSAMS 428
>YMR084w [M] KOG1268 Glucosamine 6-phosphate synthetases contain
amidotransferase and phosphosugar isomerase domains
Length = 262
Score = 314 bits (804), Expect = 3e-85
Identities = 144/225 (64%), Positives = 185/225 (82%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAIDGDREDETVIYKQIGKVS 60
MCGIFGYCNFL+EK+RGEIIDTL+EGLQ LEY+ YDS+GI+I GD + IYKQ GK+S
Sbjct: 1 MCGIFGYCNFLIEKTRGEIIDTLIEGLQALEYKEYDSSGISIQGDELESLNIYKQTGKIS 60
Query: 61 ALKKEIEAHKPNRDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDPSGTFVVVHNGIITN 120
+LK+EI+ + N++ F++HCGIAHTR ATHG ++ NCHPH SDPS FVVVHNG+ITN
Sbjct: 61 SLKEEIDLYNLNKNLPFISHCGIAHTRRATHGGLRRANCHPHNSDPSNEFVVVHNGVITN 120
Query: 121 FRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQELEGSYG 180
F +L+ LL KGY F+SDTDTECI KL+KHIYDT+++ G++ DFH LT VL+ELEGSYG
Sbjct: 121 FANLKALLMAKGYVFKSDTDTECIPKLYKHIYDTSIELGYNLDFHVLTNLVLKELEGSYG 180
Query: 181 LLCKSTHYPNEIIATRKGSPLLIGVKSEKKLKVDFVDVEFPDSEQ 225
LLC S+H+P+E++A RKGSPL+IGVK + + V+FV+VE+ D E+
Sbjct: 181 LLCTSSHFPDEVVAARKGSPLVIGVKGKTDMDVNFVEVEYLDQEE 225
>Hs19923227 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 517
Score = 67.0 bits (162), Expect = 9e-11
Identities = 52/183 (28%), Positives = 84/183 (45%), Gaps = 9/183 (4%)
Query: 2 CGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAI-DGDREDETVIYKQIGKVS 60
CG+FG ++ ++ + GL L++RG +S GI DG +K +G V+
Sbjct: 12 CGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKGMGLVN 71
Query: 61 ALKKEIEAHKPNRDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDP-SGTFVVVHNGIIT 119
+ E N +V++ GI HTR+AT G+ + NC P + G V HNG +
Sbjct: 72 HVFTE-----DNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELV 126
Query: 120 NFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQVLQELEGSY 179
N LR+ L G + +D+E I +L Y + PD+ +++E +Y
Sbjct: 127 NAARLRKKLLRHGIGLSTSSDSEMITQLL--AYTPPQEQDDTPDWVARIKNLMKEAPTAY 184
Query: 180 GLL 182
LL
Sbjct: 185 SLL 187
>CE01074 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 480
Score = 65.5 bits (158), Expect = 3e-10
Identities = 56/190 (29%), Positives = 91/190 (47%), Gaps = 17/190 (8%)
Query: 1 MCGIFGYCNFLVEKSRGEIIDTLV-EGLQRLEYRGYDSTG-IAIDGDREDETVIYKQIGK 58
MCGIFG +V E ++ L GL L++RG +STG + DG D I K G
Sbjct: 1 MCGIFG----IVAAGNYEHLNVLAANGLAALQHRGTESTGLVGSDGITRDHVEIIKGHGL 56
Query: 59 VSALKKEIEAHKPNRDAHFVTHCGIAHTRWATHGEPKQ-VNC-HPHRSDPS-GTFVVVHN 115
V + E + N + I H R++T G+ K +NC P + GT + HN
Sbjct: 57 VRDVITEDNISRMNGQSII-----IGHNRYSTAGKKKSGINCVQPFVVYTAMGTVAIAHN 111
Query: 116 GIITNFRDLRQLLTNKGYKFESDTDTECIAKLFKHIYDTNLKNGHDPDFHELTMQV---L 172
G + + + R+ + ++G +DTD+E IA++ N+K + + ++T ++ +
Sbjct: 112 GELVDAKQKRKEVLHEGVGLSTDTDSELIAQMIAKAIALNVKCKYGQEMGDITRELAVTM 171
Query: 173 QELEGSYGLL 182
L SY LL
Sbjct: 172 SALNMSYSLL 181
>7298959 [F] KOG0572 Glutamine phosphoribosylpyrophosphate amidotransferase
Length = 511
Score = 61.6 bits (148), Expect = 4e-09
Identities = 43/147 (29%), Positives = 70/147 (47%), Gaps = 8/147 (5%)
Query: 2 CGIFGYCNFLVEKSRGEIIDTLVEGLQRLEYRGYDSTGIAI-DGDREDETVIYKQIGKVS 60
CG+FG ++ +I + GL L++RG +S GIA +G ++K +G +S
Sbjct: 19 CGVFGAIACGDWPTQMDIAHVICLGLVALQHRGQESAGIATSEGKCSKNFNVHKGMGMIS 78
Query: 61 ALKKEIEAHKPNRDAHFVTHCGIAHTRWATHGEPKQVNCHPHRSDPS-GTFVVVHNGIIT 119
L + K + GI HTR++T G VNC P + G + HNG +
Sbjct: 79 TLFNDDSMKKLRGNL------GIGHTRYSTAGGSGVVNCQPFEVHTTHGALALAHNGELV 132
Query: 120 NFRDLRQLLTNKGYKFESDTDTECIAK 146
N LR+ + +G + +D+E IA+
Sbjct: 133 NNESLRREVLARGVGLSTHSDSELIAQ 159
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.137 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,896,654
Number of Sequences: 60738
Number of extensions: 1834280
Number of successful extensions: 4815
Number of sequences better than 1.0e-05: 16
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 4739
Number of HSP's gapped (non-prelim): 18
length of query: 704
length of database: 30,389,216
effective HSP length: 113
effective length of query: 591
effective length of database: 23,525,822
effective search space: 13903760802
effective search space used: 13903760802
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)